Aliases & Classifications for Hyperlucent Lung

MalaCards integrated aliases for Hyperlucent Lung:

Name: Hyperlucent Lung 12 15
Lung, Hyperlucent 45 74

Classifications:



External Ids:

Disease Ontology 12 DOID:10032
MeSH 45 D019568
UMLS 74 C0524799

Summaries for Hyperlucent Lung

MalaCards based summary : Hyperlucent Lung, also known as lung, hyperlucent, is related to bronchiolitis obliterans and mitral valve disease, and has symptoms including hemoptysis An important gene associated with Hyperlucent Lung is XK (X-Linked Kx Blood Group), and among its related pathways/superpathways are Allograft rejection and Immune response NFAT in immune response. The drugs tannic acid and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include lung, t cells and kidney, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Hyperlucent Lung

Diseases related to Hyperlucent Lung via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 191)
# Related Disease Score Top Affiliating Genes
1 bronchiolitis obliterans 29.9 IFNG IL10
2 mitral valve disease 29.6 IL10 IL4
3 bronchiolitis 29.4 IFNG IL10 IL4
4 swyer-james syndrome 10.5
5 pneumonia 10.3
6 large granular lymphocyte leukemia 10.2 IFNG IL2RA
7 hypersplenism 10.2 IFNG IL2RA
8 posterior uveitis 10.2 IFNG IL2RA
9 osteomyelitis 10.1 IFNG IL10
10 lymphadenitis 10.1 IFNG IL10
11 eumycotic mycetoma 10.1 IFNG NELFCD
12 radiculopathy 10.1 IL10 IL2RA
13 cephalosporin allergy 10.1 IFNG IL10
14 ascaridiasis 10.1 IL10 NELFCD
15 sporotrichosis 10.1 IFNG IL10
16 clonorchiasis 10.1 IFNG IL10
17 tuberculoid leprosy 10.1 IFNG IL10
18 fungal meningitis 10.1 IFNG IL10
19 multicentric castleman disease 10.1 IFNG IL10
20 castleman disease 10.1 IFNG IL10
21 chronic active epstein-barr virus infection 10.1 IFNG IL10
22 peanut allergy 10.1 IFNG IL10
23 fascioliasis 10.1 IFNG IL10
24 idiopathic neutropenia 10.1 IL10 IL2RA
25 hand, foot and mouth disease 10.1 IFNG IL10
26 spotted fever 10.1 IFNG IL10
27 hematopoietic stem cell transplantation 10.1 IFNG IL10
28 aseptic meningitis 10.1 IFNG IL10
29 primary peritoneal carcinoma 10.0 IFNG IL10
30 plasmodium vivax malaria 10.0 IFNG IL10
31 polyradiculoneuropathy 10.0 IFNG IL10
32 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.0 IFNG IL10
33 extrapulmonary tuberculosis 10.0 IFNG IL10
34 leprosy 3 10.0 IFNG IL10
35 lepromatous leprosy 10.0 IFNG IL10
36 testicular disease 10.0 IFNG IL10
37 mixed connective tissue disease 10.0 IFNG IL10
38 echinococcosis 10.0 IFNG IL10
39 idiopathic interstitial pneumonia 10.0 IFNG IL4
40 mumps 10.0 IFNG IL2RA
41 conjunctivitis 10.0 IFNG IL4
42 herpes zoster 10.0 IFNG IL10
43 melioidosis 10.0 IFNG IL10
44 mcleod syndrome 10.0
45 patent ductus arteriosus 1 10.0
46 thrombosis 10.0
47 adenoid cystic carcinoma 10.0
48 viral pneumonia 10.0
49 pneumocystosis 10.0
50 mitral valve insufficiency 10.0

Graphical network of the top 20 diseases related to Hyperlucent Lung:



Diseases related to Hyperlucent Lung

Symptoms & Phenotypes for Hyperlucent Lung

UMLS symptoms related to Hyperlucent Lung:


hemoptysis

GenomeRNAi Phenotypes related to Hyperlucent Lung according to GeneCards Suite gene sharing:

27 (show all 35)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.94 IL10
2 Increased shRNA abundance (Z-score > 2) GR00366-A-113 9.94 IL10
3 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.94 IL2RA
4 Increased shRNA abundance (Z-score > 2) GR00366-A-121 9.94 FBXW7 IL2RA
5 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.94 FBXW7
6 Increased shRNA abundance (Z-score > 2) GR00366-A-125 9.94 IL10
7 Increased shRNA abundance (Z-score > 2) GR00366-A-128 9.94 IL10
8 Increased shRNA abundance (Z-score > 2) GR00366-A-130 9.94 IL2RA
9 Increased shRNA abundance (Z-score > 2) GR00366-A-132 9.94 IL10
10 Increased shRNA abundance (Z-score > 2) GR00366-A-138 9.94 IL2RA
11 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.94 FBXW7 IL10
12 Increased shRNA abundance (Z-score > 2) GR00366-A-157 9.94 FBXW7
13 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.94 IL10
14 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.94 IL2RA
15 Increased shRNA abundance (Z-score > 2) GR00366-A-174 9.94 IL2RA
16 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.94 FBXW7
17 Increased shRNA abundance (Z-score > 2) GR00366-A-183 9.94 FBXW7
18 Increased shRNA abundance (Z-score > 2) GR00366-A-185 9.94 IL2RA
19 Increased shRNA abundance (Z-score > 2) GR00366-A-19 9.94 IL2RA
20 Increased shRNA abundance (Z-score > 2) GR00366-A-198 9.94 IL10
21 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.94 IL2RA
22 Increased shRNA abundance (Z-score > 2) GR00366-A-202 9.94 IL2RA
23 Increased shRNA abundance (Z-score > 2) GR00366-A-210 9.94 IL10
24 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.94 IL10
25 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.94 IL10 IL2RA
26 Increased shRNA abundance (Z-score > 2) GR00366-A-43 9.94 FBXW7
27 Increased shRNA abundance (Z-score > 2) GR00366-A-46 9.94 IL2RA
28 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.94 IL2RA
29 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.94 FBXW7 IL10 IL2RA
30 Increased shRNA abundance (Z-score > 2) GR00366-A-65 9.94 IL10
31 Increased shRNA abundance (Z-score > 2) GR00366-A-67 9.94 IL10 IL2RA
32 Increased shRNA abundance (Z-score > 2) GR00366-A-80 9.94 IL10
33 Increased shRNA abundance (Z-score > 2) GR00366-A-82 9.94 IL10
34 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.94 IL10
35 Increased shRNA abundance (Z-score > 2) GR00366-A-9 9.94 IL2RA

MGI Mouse Phenotypes related to Hyperlucent Lung:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.77 FBXW7 IFNG IL10 IL2RA IL4
2 hematopoietic system MP:0005397 9.73 FBXW7 IFNG IL10 IL2RA IL4 XK
3 endocrine/exocrine gland MP:0005379 9.72 FBXW7 IFNG IL10 IL2RA IL4
4 craniofacial MP:0005382 9.71 FBXW7 IFNG IL10 IL4
5 integument MP:0010771 9.55 FBXW7 IFNG IL10 IL4 XK
6 respiratory system MP:0005388 9.35 FBXW7 IFNG IL10 IL2RA IL4
7 vision/eye MP:0005391 9.02 FBXW7 IFNG IL10 IL2RA IL4

Drugs & Therapeutics for Hyperlucent Lung

Drugs for Hyperlucent Lung (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
tannic acid Approved Phase 4 1401-55-4
2
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
3 Calamus Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Non Invasive Mechanical Ventilation Versus Respiratory Rehabilitation in Hypercapnic COPD Completed NCT01377818 Phase 4

Search NIH Clinical Center for Hyperlucent Lung

Cochrane evidence based reviews: lung, hyperlucent

Genetic Tests for Hyperlucent Lung

Anatomical Context for Hyperlucent Lung

MalaCards organs/tissues related to Hyperlucent Lung:

42
Lung, T Cells, Kidney, Skin, Bone, Heart, Thyroid

Publications for Hyperlucent Lung

Articles related to Hyperlucent Lung:

(show top 50) (show all 75)
# Title Authors Year
1
Swyer-James-Macleod syndrome as a rare cause of unilateral hyperlucent lung: Three case reports. ( 30732141 )
2019
2
Unilateral hyperlucent lung. ( 30043881 )
2018
3
A unilateral hyperlucent lung - Swyer-James syndrome: A case report and literature review. ( 28138424 )
2017
4
Unilateral hyperlucent lung. ( 26933332 )
2016
5
Unilateral hyperlucent lung: An unusual cause. ( 26628784 )
2015
6
Asymptomatic Unilateral Hyperlucent Lung in a Prospective Kidney Donor. ( 27608883 )
2015
7
Unilateral hyperlucent lung associated with bronchial atresia mimicking Swyer-James syndrome. ( 25053829 )
2014
8
A case of unilateral hyperlucent lung. ( 24575998 )
2014
9
Differential diagnosis of unilateral hyperlucent lung in children. ( 23255778 )
2013
10
Unilateral hyperlucent lung: Always think ACROSS. ( 24339504 )
2013
11
Unilateral hyperlucent lung in children. ( 22528920 )
2012
12
Unilateral hyperlucent lung in a child caused by a foreign body identified with v/q scintigraphy. ( 22889792 )
2012
13
Collateral ventilation to congenital hyperlucent lung lesions assessed on xenon-enhanced dynamic dual-energy CT: an initial experience. ( 21228937 )
2011
14
Usefulness of combination of pulmonary ventilation and perfusion scintigraphy on the diagnosis of children with unilateral hyperlucent lung. ( 21869729 )
2011
15
Diagnostic approach to unilateral hyperlucent lung. ( 22279605 )
2011
16
Swyer-James-MacLeod syndrome with ipsilateral herniation of hyperinflated hyperlucent lung. ( 22679043 )
2011
17
Bronchial adenoid cystic carcinoma presenting as unilateral hyperlucent lung (Swyer-James-McLeod syndrome). ( 18157603 )
2007
18
Unilateral hyperlucent lung: MacLeod versus Swyer-James. ( 15488856 )
2004
19
An extrathoracic cause for a unilateral hyperlucent lung on a chest radiograph. ( 14732797 )
2003
20
Utility of ventilation and perfusion scan in the diagnosis of young military recruits with an incidental finding of hyperlucent lung. ( 11388574 )
2001
21
Mediastinal esophageal cyst causing unilateral hyperlucent lung. ( 10226415 )
1999
22
Hyperlucent lung in a patient with mitral valve disease. ( 9824031 )
1998
23
Hyperlucent lung secondary to homocystinuria. ( 8781109 )
1996
24
Scintigraphy, angiography and computed tomography in unilateral hyperlucent lung due to obliterative bronchiolitis. ( 7824812 )
1994
25
Congenital pulmonary lymphangiectasis presenting as a unilateral hyperlucent lung. ( 8181508 )
1994
26
A patient with a chronic cough and one hyperlucent lung. ( 1541644 )
1992
27
Transient unilateral hyperlucent lung due to mucus plugs. ( 1865034 )
1991
28
A case report of unilateral hyperlucent lung syndrome. ( 1890083 )
1991
29
Ventilation-perfusion scintigraphy in an adult with congenital unilateral hyperlucent lung. ( 2225670 )
1990
30
Presentation of bronchial mucoepidermoid carcinoma as unilateral hyperlucent lung. ( 2371078 )
1990
31
Idiopathic unilateral hyperlucent lung. ( 2666886 )
1989
32
Unilateral hyperlucent lung due to interstitial pulmonary hemorrhage from aortic dissection. ( 2913792 )
1989
33
Hyperlucent lung due to a calcium-containing bronchogenic cyst. ( 3243755 )
1988
34
Presentation of Pneumocystis carinii pneumonia as unilateral hyperlucent lung. ( 3260171 )
1988
35
Ventilation-perfusion scan in the acutely ill patient with unilateral hyperlucent lung. ( 3335918 )
1988
36
Unilateral hyperlucent lung due to bullous disease. ( 3743158 )
1986
37
Swyer-James syndrome--unilateral hyperlucent lung syndrome. A case report and review. ( 6723187 )
1984
38
Hyperlucent lung: long-term complication of adenovirus type 7 pneumonia. ( 6291737 )
1983
39
Chronic unilateral hyperlucent lung. A consecutive series of 40 patients. ( 6212408 )
1982
40
Unilateral hyperlucent lung. Non-invasive diagnosis of pulmonary artery agenesis. ( 7224230 )
1981
41
The unilateral hyperlucent lung. ( 7360420 )
1980
42
Unilateral hyperlucent lung: the case for investigation. ( 7466723 )
1980
43
Unilateral hyperlucent lung. Patent ductus arteriosus coexisting with bronchial carcinoid. ( 223818 )
1979
44
A case of hyperlucent lung. ( 470052 )
1979
45
Unilateral hyperlucent lung (Swyer-James syndrome) after severe Mycoplasma pneumoniae infection. ( 619715 )
1978
46
Unilateral hyperlucent lung associated to mitral regurgitation. ( 889471 )
1977
47
Unilateral hyperlucent lung field in subcutaneous emphysema. ( 975967 )
1976
48
Unilateral hyperlucent lung (Swyer-James syndrome). ( 1070312 )
1976
49
Unilateral hyperlucent lung with decreased vascular markings (Swyer-James syndrome). ( 1124208 )
1975
50
Hyperlucent lung after radiation therapy. ( 1155850 )
1975

Variations for Hyperlucent Lung

Expression for Hyperlucent Lung

Search GEO for disease gene expression data for Hyperlucent Lung.

Pathways for Hyperlucent Lung

Pathways related to Hyperlucent Lung according to GeneCards Suite gene sharing:

(show all 28)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.61 IFNG IL10 IL2RA IL4
2
Show member pathways
12.39 IFNG IL10 IL2RA IL4
3
Show member pathways
12.35 IFNG IL10 IL2RA IL4
4
Show member pathways
12.32 IFNG IL10 IL4
5 12.27 IFNG IL10 IL2RA IL4
6
Show member pathways
12.07 IFNG IL10 IL2RA IL4
7
Show member pathways
12.02 IFNG IL10 IL4
8
Show member pathways
12.01 IFNG IL10 IL2RA IL4
9
Show member pathways
11.84 IFNG IL10 IL2RA IL4
10
Show member pathways
11.78 IFNG IL2RA IL4
11 11.68 IFNG IL10 IL2RA
12
Show member pathways
11.53 IFNG IL2RA IL4
13 11.52 IFNG IL10 IL2RA IL4
14
Show member pathways
11.46 IL2RA IL4
15 11.46 IFNG IL10 IL4
16 11.43 IL10 IL4
17
Show member pathways
11.41 IFNG IL2RA
18 11.31 IL10 IL4
19 11.31 IFNG IL10
20 11.18 IFNG IL10
21 11.16 IFNG IL10 IL2RA IL4
22 11.1 IFNG IL4
23 11.06 IFNG IL2RA IL4
24
Show member pathways
11.05 IFNG IL2RA
25 11.03 IFNG IL2RA
26 10.96 IFNG IL10 IL4
27 10.85 IFNG IL10 IL4
28 10.59 IFNG IL10 IL2RA IL4

GO Terms for Hyperlucent Lung

Biological processes related to Hyperlucent Lung according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.61 IL10 IL2RA IL4
2 immune response GO:0006955 9.56 IFNG IL10 IL2RA IL4
3 positive regulation of T cell proliferation GO:0042102 9.49 IL2RA IL4
4 interleukin-12-mediated signaling pathway GO:0035722 9.48 IFNG IL10
5 negative regulation of T cell proliferation GO:0042130 9.46 IL10 IL2RA
6 negative regulation of endothelial cell apoptotic process GO:2000352 9.4 IL10 IL4
7 positive regulation of T cell differentiation GO:0045582 9.37 IL2RA IL4
8 regulation of regulatory T cell differentiation GO:0045589 9.32 IFNG IL2RA
9 positive regulation of MHC class II biosynthetic process GO:0045348 9.16 IL10 IL4
10 regulation of isotype switching GO:0045191 8.96 IL10 IL4
11 type 2 immune response GO:0042092 8.62 IL10 IL4

Molecular functions related to Hyperlucent Lung according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.8 IFNG IL10 IL4

Sources for Hyperlucent Lung

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....