1 |
A novel point mutation in the insulin gene giving rise to hyperproinsulinemia.
61
57
6
|
Warren-Perry MG...Turner RC
|
9141561 |
1997 |
2 |
A mutation in the B chain coding region is associated with impaired proinsulin conversion in a family with hyperproinsulinemia.
57
6
61
|
Chan SJ...Steiner DF
|
3470784 |
1987 |
3 |
Familial hyperproinsulinemia due to a proposed defect in conversion of proinsulin to insulin.
6
57
61
|
Gruppuso PA...Schwartz R
|
6382002 |
1984 |
4 |
Studies on mutant human insulin genes: identification and sequence analysis of a gene encoding [SerB24]insulin.
57
6
|
Haneda M...Steiner DF
|
6312455 |
1983 |
5 |
Three mutant insulins in man.
6
57
|
Shoelson S...Tager H
|
6339950 |
1983 |
6 |
Loss of a restriction endonuclease cleavage site in the gene of a structurally abnormal human insulin.
6
57
|
Kwok SC...Steiner DF
|
6261753 |
1981 |
7 |
Diabetes due to secretion of an abnormal insulin.
57
6
|
Given BD...Poucher R
|
7350438 |
1980 |
8 |
A structurally abnormal insulin causing human diabetes.
57
6
|
Tager H...Poucher R
|
381941 |
1979 |
9 |
Hyperproinsulinemia in a three-generation Caucasian family due to mutant proinsulin (Arg65-His) not associated with imparied glucose tolerance: the contribution of mutant proinsulin to insulin bioactivity.
6
61
|
Roder ME...Nauck MA
|
8636380 |
1996 |
10 |
A novel point mutation in the human insulin gene giving rise to hyperproinsulinemia (proinsulin Kyoto).
6
61
|
Yano H...Seino Y
|
1601997 |
1992 |
11 |
A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway.
61
6
|
Carroll RJ...Steiner DF
|
3057496 |
1988 |
12 |
A superactive insulin: [B10-aspartic acid]insulin(human).
6
61
|
Schwartz GP...Katsoyannis PG
|
3306677 |
1987 |
13 |
Hyperproinsulinemia in a family with a proposed defect in conversion is linked to the insulin gene.
6
61
|
Elbein SC...Permutt MA
|
2991050 |
1985 |
14 |
Posttranslational cleavage of proinsulin is blocked by a point mutation in familial hyperproinsulinemia.
6
61
|
Shibasaki Y...Takaku F
|
4019786 |
1985 |
15 |
Familial hyperproinsulinemia. Two cohorts secreting indistinguishable type II intermediates of proinsulin conversion.
6
61
|
Robbins DC...Tager HS
|
6368587 |
1984 |
16 |
Familial hyperproinsulinemia: partial characterization of circulating proinsulin-like material.
57
61
|
Gabbay KH...Rubenstein AH
|
288074 |
1979 |
17 |
Familial hyperproinsulinemia. An autosomal dominant defect.
61
57
|
Gabbay KH...Rubenstein AH
|
815812 |
1976 |
18 |
Familial hyperproinsulinaemia due to a mutation substituting histidine for arginine at position 65 in proinsulin: identification of the mutation by restriction enzyme mapping.
6
|
Collinet M...Robert JJ
|
9667398 |
1998 |
19 |
Paradoxical structure and function in a mutant human insulin associated with diabetes mellitus.
6
|
Hua QX...Weiss MA
|
8421693 |
1993 |
20 |
Structurally abnormal insulin in a diabetic patient. Characterization of the mutant insulin A3 (Val----Leu) isolated from the pancreas.
6
|
Sakura H...Hirata H
|
3537011 |
1986 |
21 |
Familial hyperinsulinemia associated with secretion of an abnormal insulin, and coexistence of insulin resistance in the propositus.
57
|
Vinik AI...Tsai ST
|
3512591 |
1986 |
22 |
Diabetes due to secretion of a structurally abnormal insulin (insulin Wakayama). Clinical and functional characteristics of [LeuA3] insulin.
6
|
Nanjo K...Given BD
|
3511099 |
1986 |
23 |
Familial hyperinsulinemia due to a structurally abnormal insulin. Definition of an emerging new clinical syndrome.
57
|
Haneda M...Zeidler A
|
6371526 |
1984 |
24 |
Identification of a mutant human insulin predicted to contain a serine-for-phenylalanine substitution.
57
|
Shoelson S...Tager H
|
6424111 |
1983 |
25 |
A human proinsulin variant at arginine 65.
6
|
Robbins DC...Tager HS
|
7242673 |
1981 |
26 |
The insulinopathies.
57
|
Gabbay KH
|
7350441 |
1980 |
27 |
Beta Cell Function is Disrupted in Patients with Systemic Lupus Erythematosus.
61
|
Garcia-Dorta A...Ferraz-Amaro I
|
33369681 |
2020 |
28 |
Plasma levels of acylated ghrelin in patients with insulinoma and expression of ghrelin and its receptor in insulinomas.
61
|
Wu HY...Chen YJ
|
32124259 |
2020 |
29 |
eIF4G1 and carboxypeptidase E axis dysregulation in O-GlcNAc transferase-deficient pancreatic β-cells contributes to hyperproinsulinemia in mice.
61
|
Jo S...Alejandro EU
|
31300553 |
2019 |
30 |
[Diagnostics value and regulatory functions of roinsulin.]
61
|
Poteryaeva ON...Usynin IF
|
31408590 |
2019 |
31 |
Increased β-Cell Workload Modulates Proinsulin-to-Insulin Ratio in Humans.
61
|
Mezza T...Giaccari A
|
30131390 |
2018 |
32 |
Hyperproinsulinemia in obesity and in type 2 diabetes and its relation to cardiovascular disease.
61
|
Roder ME
|
30058886 |
2017 |
33 |
Dissecting carboxypeptidase E: properties, functions and pathophysiological roles in disease.
61
|
Ji L...Lan R
|
28348001 |
2017 |
34 |
How does radiotherapy impact swallowing function in nasopharynx and oropharynx cancer? Short-term results of a prospective study.
61
|
Ursino S...Fattori B
|
27070541 |
2016 |
35 |
Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes.
61
|
Yang Y...Chan L
|
27035557 |
2016 |
36 |
Both fasting and glucose-stimulated proinsulin levels predict hyperglycemia and incident type 2 diabetes: a population-based study of 9,396 Finnish men.
61
|
Vangipurapu J...Laakso M
|
25853252 |
2015 |
37 |
GLP-1 analog liraglutide enhances proinsulin processing in pancreatic β-cells via a PKA-dependent pathway.
61
|
Wang L...Hong T
|
25051441 |
2014 |
38 |
Role of dietary fats in modulating cardiometabolic risk during moderate weight gain: a randomized double-blind overfeeding trial (LIPOGAIN study).
61
|
Iggman D...Riserus U
|
25319187 |
2014 |
39 |
Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells.
61
|
Liew CW...Kulkarni RN
|
24843127 |
2014 |
40 |
Estimated proinsulin processing activity of prohormone convertase (PC) 1/3 rather than PC2 is decreased in pancreatic β-cells of type 2 diabetic patients.
61
|
Ozawa S...Ishida H
|
24705588 |
2014 |
41 |
HPRI data tracks. Urology workforce trends.
61
|
Neuwahl S...Ricketts T
|
22315881 |
2012 |
42 |
Admission proinsulin is associated with mortality in patients with admission hyperglycemia during acute coronary syndrome: results from a pilot observational study.
61
|
Farhan S...Huber K
|
21784763 |
2011 |
43 |
Differential regulation and localization of carboxypeptidase D and carboxypeptidase E in human and mouse β-cells.
61
|
Chu KY...Johnson JD
|
21628999 |
2011 |
44 |
Proinsulin maturation disorder is a contributor to the defect of subsequent conversion to insulin in β-cells.
61
|
Wang J...Osei K
|
21723250 |
2011 |
45 |
HPRI data tracks. Developing an index of surgical underservice.
61
|
Ricketts TC...McGee V
|
22315900 |
2011 |
46 |
The ACS HPRI: shaping surgical workforce policy through evidence-based analyses.
61
|
Fraher EP...Thompson KW
|
22312822 |
2011 |
47 |
Independent relationships of obesity and insulin resistance with serum proinsulin level in prepubertal children with normal glucose tolerance.
61
|
Lee YA...Yang SW
|
21214701 |
2011 |
48 |
Insulin gene mutations and diabetes.
61
|
Nishi M...Nanjo K
|
24843467 |
2011 |
49 |
Bileopancreatic diversion with duodenal switch lowers both early and late phases of glucose, insulin and proinsulin responses after meal.
61
|
Johansson HE...Zethelius B
|
20198453 |
2010 |
50 |
Mutant proinsulin proteins associated with neonatal diabetes are retained in the endoplasmic reticulum and not efficiently secreted.
61
|
Park SY...Bell GI
|
20034470 |
2010 |