Aliases & Classifications for Hypertension, Diastolic

MalaCards integrated aliases for Hypertension, Diastolic:

Name: Hypertension, Diastolic 56
Hypertension, Diastolic, Resistance to 56 29 13 6 39
Diastolic Hypertension 54 71

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant


HPO:

31
hypertension, diastolic:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM 56 608622
MedGen 41 C1837739
SNOMED-CT via HPO 68 263681008
UMLS 71 C0235222

Summaries for Hypertension, Diastolic

OMIM : 56 Hypertension is a significant risk factor for cardiac and renal disease, arteriosclerosis, retinopathy, and stroke. Systolic hypertension reflects an increase in the force of cardiac contraction, whereas diastolic hypertension reflects an increase in peripheral vascular resistance. Normalization of blood pressure is associated with reductions in morbidity and mortality related to end-organ damage. (608622)

MalaCards based summary : Hypertension, Diastolic, also known as hypertension, diastolic, resistance to, is related to diastolic heart failure and renovascular hypertension. An important gene associated with Hypertension, Diastolic is KCNMB1 (Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 1), and among its related pathways/superpathways are Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics and Renin secretion. The drugs Angiotensin II and Amlodipine have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and thyroid, and related phenotypes are elevated diastolic blood pressure and renal/urinary system

Related Diseases for Hypertension, Diastolic

Diseases related to Hypertension, Diastolic via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 112, show less)
# Related Disease Score Top Affiliating Genes
1 diastolic heart failure 30.3 REN ACE
2 renovascular hypertension 29.6 REN ACE
3 carotid stenosis 29.5 REN ACE
4 hypertension, essential 28.3 REN KCNMB1 KCNMA1 GGT1 ACE
5 episodic ataxia, type 4 10.2 KCNMB1 KCNIP1
6 episodic ataxia, type 3 10.2 KCNMB1 KCNIP1
7 systolic heart failure 10.1
8 hypoaldosteronism 10.0 REN ACE
9 renal artery obstruction 10.0 REN ACE
10 orthostatic proteinuria 10.0 REN ACE
11 cholesterol embolism 10.0 REN ACE
12 potter's syndrome 10.0 REN ACE
13 hypertensive encephalopathy 10.0 REN ACE
14 kidney papillary necrosis 10.0 REN ACE
15 generalized atherosclerosis 10.0 REN ACE
16 vein disease 10.0 GGT1 ACE
17 severe nonproliferative diabetic retinopathy 10.0 REN ACE
18 fibromuscular dysplasia 10.0 REN ACE
19 kidney hypertrophy 10.0 REN ACE
20 hypertensive retinopathy 10.0 REN ACE
21 pure autonomic failure 10.0 REN ACE
22 renal artery disease 10.0 REN ACE
23 pseudohyperkalemia, familial, 2, due to red cell leak 10.0 REN ACE
24 left bundle branch hemiblock 10.0 REN ACE
25 central sleep apnea 10.0 REN ACE
26 sleep apnea 10.0 REN ACE
27 chronic pyelonephritis 10.0 REN ACE
28 anuria 10.0 REN ACE
29 alcoholic cardiomyopathy 10.0 REN ACE
30 diabetic autonomic neuropathy 10.0 REN ACE
31 cardiac tamponade 10.0 REN ACE
32 tricuspid valve insufficiency 10.0 REN ACE
33 pulmonary hypertension 10.0
34 vascular disease 10.0
35 tricuspid valve disease 10.0 REN ACE
36 microvascular complications of diabetes 3 10.0 REN ACE
37 aortic valve insufficiency 10.0 REN ACE
38 pyelitis 10.0 REN ACE
39 mitral valve stenosis 10.0 REN ACE
40 renal tubular dysgenesis 10.0 REN ACE
41 hepatorenal syndrome 10.0 REN ACE
42 mitral valve insufficiency 10.0 REN ACE
43 malignant hypertension 9.9 REN ACE
44 pericardium disease 9.9 REN ACE
45 autonomic nervous system disease 9.9 REN ACE
46 ureteral disease 9.9 REN ACE
47 apnea, obstructive sleep 9.9 REN ACE
48 hepatic vascular disease 9.9 REN GGT1
49 renal hypertension 9.9 REN ACE
50 renal dysplasia 9.9 REN ACE
51 coronavirus infectious disease 9.9 REN ACE
52 iga glomerulonephritis 9.9 REN ACE
53 pericardial effusion 9.9 REN ACE
54 hypertensive heart disease 9.9 REN ACE
55 mineral metabolism disease 9.9 REN ACE
56 acute cystitis 9.9 REN ACE
57 adrenal gland disease 9.9 REN ACE
58 obstructive jaundice 9.9 REN GGT1
59 interstitial nephritis 9.9 REN ACE
60 mitral valve disease 9.9 REN ACE
61 extrinsic cardiomyopathy 9.9 REN ACE
62 carotid artery disease 9.9 REN ACE
63 obstructive nephropathy 9.9 REN ACE
64 patent ductus arteriosus 1 9.9 REN ACE
65 oligohydramnios 9.9 REN ACE
66 sleep disorder 9.9 REN ACE
67 heart conduction disease 9.8 REN ACE
68 eclampsia 9.8 REN ACE
69 retinal vascular disease 9.8 REN ACE
70 macular dystrophy, dominant cystoid 9.8 KCNMA1 ACE
71 diabetes mellitus, noninsulin-dependent 9.8
72 hypercholesterolemia, familial, 1 9.8
73 pheochromocytoma 9.8
74 asplenia, isolated congenital 9.8
75 stroke, ischemic 9.8
76 wilms tumor 5 9.8
77 hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy 9.8
78 coronary heart disease 1 9.8
79 myocardial infarction 9.8
80 human immunodeficiency virus type 1 9.8
81 adrenal gland pheochromocytoma 9.8
82 cardiac arrest 9.8
83 cryptococcal meningitis 9.8
84 heart disease 9.8
85 hypertrophic cardiomyopathy 9.8
86 arteriosclerosis 9.8
87 lipid metabolism disorder 9.8
88 hyperglycemia 9.8
89 liver cirrhosis 9.8
90 congestive heart failure 9.8
91 cerebrovascular disease 9.8
92 chronic kidney disease 9.8
93 acute myocardial infarction 9.8
94 meningitis 9.8
95 macular retinal edema 9.8 KCNMA1 ACE
96 diabetic neuropathy 9.8 REN ACE
97 hypokalemia 9.8 REN ACE
98 pulmonary edema 9.8 REN ACE
99 sexual disorder 9.8 KCNMA1 ACE
100 vesicoureteral reflux 1 9.8 REN ACE
101 hyperuricemia 9.7 REN GGT1
102 heart valve disease 9.7 REN ACE
103 intrinsic cardiomyopathy 9.7 REN ACE
104 impotence 9.7 KCNMA1 ACE
105 uremia 9.7 REN ACE
106 polycystic kidney disease 1 with or without polycystic liver disease 9.6 REN ACE
107 acute kidney tubular necrosis 9.6 REN GGT1 ACE
108 urinary tract obstruction 9.6 REN GGT1 ACE
109 inherited metabolic disorder 9.6 REN GGT1 ACE
110 cardiovascular system disease 9.5 REN GGT1 ACE
111 aortic valve disease 2 9.5 REN ACE
112 orthostatic intolerance 9.4 REN ACE

Graphical network of the top 20 diseases related to Hypertension, Diastolic:



Diseases related to Hypertension, Diastolic

Symptoms & Phenotypes for Hypertension, Diastolic

Human phenotypes related to Hypertension, Diastolic:

31 (showing 1, show less)
# Description HPO Frequency HPO Source Accession
1 elevated diastolic blood pressure 31 HP:0005117

Symptoms via clinical synopsis from OMIM:

56
Cardiovascular Vascular:
resistance to moderate and severe diastolic hypertension

Clinical features from OMIM:

608622

MGI Mouse Phenotypes related to Hypertension, Diastolic:

45 (showing 1, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 9.02 ACE GGT1 KCNMA1 KCNMB1 REN

Drugs & Therapeutics for Hypertension, Diastolic

Drugs for Hypertension, Diastolic (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 95, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Angiotensin II Approved, Investigational Phase 4 4474-91-3, 11128-99-7, 68521-88-0 172198
2
Amlodipine Approved Phase 4 88150-42-9 2162
3
Lisinopril Approved, Investigational Phase 4 76547-98-3, 83915-83-7 5362119
4
Nebivolol Approved, Investigational Phase 4 99200-09-6, 118457-14-0, 152520-56-4 71301
5
Enalapril Approved, Vet_approved Phase 4 75847-73-3 40466924 5362032
6
Enalaprilat Approved Phase 4 76420-72-9 6917719
7
Simvastatin Approved Phase 4 79902-63-9 54454
8
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
9
Ranolazine Approved, Investigational Phase 4 142387-99-3, 95635-55-5 56959
10
Ambrisentan Approved, Investigational Phase 4 177036-94-1 6918493
11 Angiotensin II Type 1 Receptor Blockers Phase 4
12 Angiotensinogen Phase 4
13 Angiotensin Receptor Antagonists Phase 4
14 Giapreza Phase 4
15 Angiotensin-Converting Enzyme Inhibitors Phase 4
16 Adrenergic beta-Agonists Phase 4
17 Cardiotonic Agents Phase 4
18 Protective Agents Phase 4
19 Hypolipidemic Agents Phase 4
20 Lipid Regulating Agents Phase 4
21 Anticholesteremic Agents Phase 4
22 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
23 Antimetabolites Phase 4
24 Sodium Channel Blockers Phase 4
25 Diuretics, Potassium Sparing Phase 4
26
Hydrochlorothiazide Approved, Vet_approved Phase 3 58-93-5 3639
27
Benazepril Approved, Investigational Phase 3 86541-75-5 5362124
28
Guanfacine Approved, Investigational Phase 3 29110-47-2 3519
29
Doxorubicin Approved, Investigational Phase 3 23214-92-8 31703
30
Trastuzumab Approved, Investigational Phase 3 180288-69-1 9903
31
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
32
Docetaxel Approved, Investigational Phase 3 114977-28-5 148124
33
Clotrimazole Approved, Vet_approved Phase 3 23593-75-1 2812
34
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
35
Coal tar Approved Phase 3 8007-45-2
36
Etanercept Approved, Investigational Phase 3 185243-69-0
37 Darusentan Investigational Phase 3 171714-84-4
38 diuretics Phase 3
39 Endothelin Receptor Antagonists Phase 3
40 Mitogens Phase 3
41
Liposomal doxorubicin Phase 3 31703
42 Alkylating Agents Phase 3
43 Tubulin Modulators Phase 3
44 Anti-Bacterial Agents Phase 3
45 Antibiotics, Antitubercular Phase 3
46 Antimitotic Agents Phase 3
47 Antineoplastic Agents, Immunological Phase 3
48 Analgesics, Non-Narcotic Phase 3
49 Analgesics Phase 3
50 Anti-Inflammatory Agents Phase 3
51 Antirheumatic Agents Phase 3
52 Anti-Inflammatory Agents, Non-Steroidal Phase 3
53 Immunosuppressive Agents Phase 3
54 Immunologic Factors Phase 3
55 Anti-Infective Agents Phase 3
56 Dermatologic Agents Phase 3
57 Antifungal Agents Phase 3
58 Cyclosporins Phase 3
59 Calcineurin Inhibitors Phase 3
60 Gastrointestinal Agents Phase 3
61
Nitric Oxide Approved Phase 1 10102-43-9 145068
62 Grape Approved Phase 1
63
Resveratrol Investigational Phase 1 501-36-0 445154
64
Quercetin Experimental, Investigational Phase 1 117-39-5 5280343
65 Anthocyanidin Phase 1
66 Antioxidants Phase 1
67 Platelet Aggregation Inhibitors Phase 1
68 Grape Seed Extract Phase 1
69
Midazolam Approved, Illicit 59467-70-8 4192
70
Propofol Approved, Investigational, Vet_approved 2078-54-8 4943
71
Desflurane Approved 57041-67-5 42113
72
Sevoflurane Approved, Vet_approved 28523-86-6 5206
73
Telmisartan Approved, Investigational 144701-48-4 65999
74
Darunavir Approved 206361-99-1, 635728-49-3 213039
75
Rilpivirine Approved 500287-72-9
76
Dolutegravir Approved 1051375-16-6 54726191
77
Cobicistat Approved 1004316-88-4
78
Tenofovir Experimental, Investigational 147127-20-6 464205
79 Hypnotics and Sedatives
80 Psychotropic Drugs
81 Anti-Anxiety Agents
82 Anesthetics, General
83 Anesthetics
84 GABA Modulators
85 Anesthetics, Inhalation
86 Anesthetics, Intravenous
87 Sodium Chloride Symporter Inhibitors
88 HIV Protease Inhibitors
89
protease inhibitors
90 Anti-HIV Agents
91 Integrase Inhibitors
92 HIV Integrase Inhibitors
93 Reverse Transcriptase Inhibitors
94 Antiviral Agents
95 Anti-Retroviral Agents

Interventional clinical trials:

(showing 24, show less)
# Name Status NCT ID Phase Drugs
1 A Randomized, Double-blind, Parallel-Group Study to Evaluate the Effects of First-Line Treatment With a Free Combination of Nebivolol and Lisinopril Compared With Placebo and the Monotherapy Components on Blood Pressure in Patients With Stage 2 Diastolic Hypertension Completed NCT01218100 Phase 4 nebivolol and lisinopril (free combination);nebivolol monotherapy;lisinopril monotherapy;placebo
2 Effect of the Addition of Simvastatin to Enalapril in Hypertensive Individuals With Average Cholesterol Levels and Diastolic Dysfunction Completed NCT01061450 Phase 4 Simvastatin;Placebo
3 Valsartan Versus Amlodipine Effect on Left Ventricular Multidirectional Deformation and Adipocytokines Level in Hypertensive Patients: Speckle Tracking Echocardiography Completed NCT03990480 Phase 4 valsartan (160 mg/d);amlodipine (10 mg/d).
4 Proof of Concept Study of Ranolazine in the Treatment of Pulmonary Hypertension Associated With Diastolic Left Ventricular Dysfunction Completed NCT02133352 Phase 4 Ranolazine
5 Safety and Efficacy Trial Using Ambrisentan for Pulmonary Hypertension Associated With Congestive Heart Failure With Preserved Left Ventricular Ejection Fraction Terminated NCT00840463 Phase 4 Ambrisentan
6 A Multicenter, Group Study to Evaluate the Safety and Efficacy of Amlodipine and Benazepril Administered in Combination Compared to Amlodipine Monotherapy in Hypertensive Patients Not Adequately Controlled With Amlodipine Alone Completed NCT00171366 Phase 3 amlodipine/benazepril
7 An Eight-week Multicenter Study to Evaluate the Efficacy and Safety of the Combination of Aliskiren / HCTZ (150/25 mg and 300/25 mg) in Comparison With HCTZ 25 mg in Patients With Essential Hypertension Not Adequately Responsive to HCTZ 25 mg Monotherapy Completed NCT00387517 Phase 3 Aliskiren/HCTZ
8 An Eight-week Multicenter Study to Evaluate the Efficacy and Safety of the Combination of Aliskiren / HCTZ (300/12.5 mg and 300/25 mg) in Comparison With Aliskiren 300 mg in Patients With Essential Hypertension Not Adequately Responsive to Aliskiren 300 mg Monotherapy Completed NCT00386139 Phase 3 Aliskiren/HCTZ
9 A Phase 3 Randomized, Double-Blind, Placebo- and Active-Controlled, Multi-center, Parallel Group Study to Evaluate the Safety and Efficacy of Darusentan in Subjects With Resistant Hypertension Receiving Combination Therapy With Three or More Antihypertensive Drugs, Including a Diuretic, as Compared to Guanfacine or Placebo (Protocol DAR-312) Completed NCT00389779 Phase 3 Darusentan;Guanfacine;Darusentan Placebo
10 A Phase III, Randomized, Two-armed, Patient-outcome Assessor-data Analyzer Blinded, Parallel Active Controlled Non-Inferiority Clinical Trial Study of AryoTrust™ (Aryogen Trastuzumab ) Efficacy and Safety in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer in Comparison to Herceptin® (Genentech/Roche) Control. Recruiting NCT03425656 Phase 3 Trastuzumab plus docetaxel (for 4 21-day cycles) after four 14-day cycles of Doxorubicin plus cyclophosphamide
11 NATIENS: A Phase III Randomized Double-Blinded Placebo Controlled Study to Determine the Optimal Management and Mechanisms of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Not yet recruiting NCT02987257 Phase 3 Harmonized supportive care;Cyclosporine 5 mg/kg bid days 0-14;Etanercept 50 mg sc day 0 and day 3
12 Treatment Targets for Chronic Hypertension in Pregnancy Withdrawn NCT00194974 Phase 1, Phase 2 methyldopa;labetalol;nifedipine;clonidine
13 Mechanisms of the Relaxation Response in Elderly Hypertensives Completed NCT00913991 Phase 1
14 GRAPe Seed Extract and Ventriculovascular Investigation in Normal Ejection-Fraction Heart Failure Completed NCT01185067 Phase 1 grape seed extract (MegaNatural BP, Polyphenolics, Inc.)
15 Transcatheter Renal Denervation in Heart Failure With Normal Left Ventricular Ejection Fraction - a Safety and Efficacy Study of Irrigated Radiofrequency Catheter Unknown status NCT02115230
16 Post Operative Cognitive Recovery and Neuropsychological Complications After General Anesthesia. A Comparison Between Different Techniques of Anesthesia: A Multi-Center Observational Study Unknown status NCT00507195 Hypnotics: propofol, sevoflurane, desflurane,desflurane,midazolam
17 Observational Study in Everyday Medical Practice of the Effectiveness of Telmisartan for Treatment of Isolated Systolic Hypertension in Comparison With Systolic/Diastolic Hypertension in Patients Aged 55 or Older Completed NCT02242877 Telmisartan;Telmisartan combined with hydrochlorothiazide
18 Effects of Nebivolol on Exercise Tolerance and Left Ventricular Systolic and Diastolic Function Completed NCT01056718 Nebivolol
19 Does Treating Obstructive Sleep Apnea in Obese Canadian Youth Improve Blood Sugar Control? A Multi-Centered Prospective Cohort Study Completed NCT01116375
20 Impedance Cardiography in the Evaluation of Left Ventricular Diastolic Dysfunction in Patients With Arterial Hypertension Study (IMPEDDANS) Completed NCT03209141
21 Short Term Neurobehavioural Outcomes in Late Preterm Neonates Born to Pre Eclamptic Mothers : a Prospective Observational Study Completed NCT02443259
22 Prevalence of Thyroid Function Abnormalities in HIV-infected Patients: State of Play in 2012 Recruiting NCT03149354
23 What is the Impact of Current HIV Medication Regimens on Endothelial Dysfunction? Recruiting NCT03782142 Tenofovir;Rilpivirine;Prezcobix;Dolutegravir
24 Role of EECP Therapy in Patients With Resistant Hypertension Withdrawn NCT00953797

Search NIH Clinical Center for Hypertension, Diastolic

Genetic Tests for Hypertension, Diastolic

Genetic tests related to Hypertension, Diastolic:

# Genetic test Affiliating Genes
1 Hypertension, Diastolic, Resistance to 29 KCNMB1

Anatomical Context for Hypertension, Diastolic

MalaCards organs/tissues related to Hypertension, Diastolic:

40
Heart, Endothelial, Thyroid, Breast, Kidney, Testes, Lung

Publications for Hypertension, Diastolic

Articles related to Hypertension, Diastolic:

(showing 452, show less)
# Title Authors PMID Year
1
Gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertension. 6 56
15057310 2004
2
E65 K polymorphism in KCNMB1 gene is not associated with ischaemic heart disease in Spanish patients. 6
16155733 2005
3
A longitudinal study on the relationship between shift work and the progression of hypertension in male Japanese workers. 61 54
16269958 2005
4
Effects of perindopril on elastic and structural properties of large arteries in essential hypertension. 61 54
15229761 2004
5
[The TEAM study--a study of the effectiveness and tolerance of treatment of essential hypertension with a fixed combination of trandolapril and verapamil]. 61 54
9820054 1998
6
Treatment of senile hypertension: the Fosinopril in Old Patients Study (FOPS). 54 61
9366282 1997
7
I/D polymorphism of the angiotensin-converting enzyme gene does not predict isolated systolic or systolic-diastolic hypertension in the elderly. 54 61
8733034 1996
8
Angiotensin converting enzyme inhibitors as initial monotherapy in severe hypertension. Quinapril and captopril. 54 61
1747216 1991
9
Hemodynamic and renin responses to nifedipine in renovascular hypertension. 54 61
2405611 1990
10
A robust diving response in the laboratory mouse. 61
31552491 2019
11
Hypertension, diastolic stress test, and HFpEF: Does new scoring system change something? 61
31769582 2019
12
Microvascular decompression in patients with hemifacial spasm. 61
31617334 2019
13
Prevalence of diabetes and cardio-metabolic risk factors in young men in the United Arab Emirates: A cross-sectional national survey. 61
31592445 2019
14
Hypertension and its risk factors among male adolescents in intermediate and secondary schools in Sakaka City, Aljouf Region of Saudi Arabia. 61
31417059 2019
15
Ranolazine: Multifaceted Role beyond Coronary Artery Disease, a Recent Perspective. 61
31007857 2018
16
ASSOCIATION BETWEEN COMPONENTS OF METABOLIC SYNDROME AND COGNITIVE DYSFUNCTION: CROSS-SECTIONAL STUDY AMONG THE POPULATION OF THE TURKESTAN REGION. 61
29905556 2018
17
Factors associated with residual urine volume preservation in patients undergoing hemodialysis for end-stage kidney disease in Kinshasa. 61
29554877 2018
18
Sex Differences in Heart Failure. 61
30051405 2018
19
Anthropometric and cardiometabolic risk factors in parents and child obesity in Segamat, Malaysia. 61
29106558 2017
20
Mid-term results of bilateral lung transplant with postoperatively extended intraoperative extracorporeal membrane oxygenation for severe pulmonary hypertension. 61
28329232 2017
21
Chronic obstructive pulmonary disease and atrial fibrillation: An unknown relationship. 61
28188041 2017
22
Effects of pentoxifylline on hemodynamic, hemorheological, and microcirculatory parameters in young SHRs during arterial hypertension development. 61
28722518 2017
23
Role of Ranolazine in cardiovascular disease and diabetes: Exploring beyond angina. 61
27838121 2017
24
Global longitudinal strain predicts incident atrial fibrillation and stroke occurrence after acute myocardial infarction. 61
27858918 2016
25
The Inter-rater Reliability of Echocardiographic Diastolic Function Evaluation Among Emergency Physician Sonographers. 61
27614538 2016
26
Sickle cell anemia mice develop a unique cardiomyopathy with restrictive physiology. 61
27503873 2016
27
A Randomized, Double-blind, Candesartan-controlled, Parallel Group Comparison Clinical Trial to Evaluate the Antihypertensive Efficacy and Safety of Fimasartan in Patients with Mild to Moderate Essential Hypertension. 61
27161546 2016
28
The efficacy of resveratrol in controlling hypertension: study protocol for a randomized, crossover, double-blinded, placebo-controlled trial. 61
27339453 2016
29
Correlates of Blood Pressure According to Early, On Time, and Late Maturation in Adolescents. 61
26408345 2016
30
[Hypertension Control at the Primary Health Care: A Comparison Among Portuguese Natives and Portuguese Speaking African Coutries Immigrants]. 61
27285095 2016
31
Diminazene Aceturate Improves Cardiac Fibrosis and Diastolic Dysfunction in Rats with Kidney Disease. 61
27571511 2016
32
Pathophysiological effects of different risk factors for heart failure. 61
27042319 2016
33
Valacyclovir and Acyclovir Neurotoxicity With Status Epilepticus. 61
24368610 2016
34
Genotype Correlations With Blood Pressure and Efficacy From a Randomized Phase III Trial of Second-Line Axitinib Versus Sorafenib in Metastatic Renal Cell Carcinoma. 61
25816720 2015
35
Antibodies against native and oxidized cardiolipin and phosphatidylserine and phosphorylcholine in atherosclerosis development. 61
25473948 2014
36
Perceived racial discrimination and hypertension: a comprehensive systematic review. 61
24417692 2014
37
Cardiac mechanics and ventricular twist by three-dimensional strain analysis in relation to B-type natriuretic peptide as a clinical prognosticator for heart failure patients. 61
25545637 2014
38
Transarterial treatment of congenital renal arteriovenous fistulas. 61
23810295 2013
39
Probable carvedilol-induced thrombocytopenia. 61
23515512 2013
40
Effects of add-on nebivolol on blood pressure and glucose parameters in hypertensive patients with prediabetes. 61
23551727 2013
41
Blood pressure load in adults with treated hypertension. 61
23633274 2013
42
Progression of myocardial remodeling and mechanical dysfunction in the spontaneously hypertensive rat. 61
23001837 2012
43
Analysis of various etiologies of hypertension in patients hospitalized in the endocrinology division. 61
22212439 2012
44
Prediction of individuals prone to suffer from early onset of hypertension. 61
23671955 2012
45
Aldosterone and the heart: from basic research to clinical evidence. 61
22095099 2012
46
Clinical and echocardiographic correlates of intra-atrial conduction delay. 61
21846646 2011
47
Switching patients with uncontrolled hypertension on amlodipine 10 mg to single-pill combinations of telmisartan and amlodipine: results of the TEAMSTA-10 study. 61
21955225 2011
48
Telmisartan and amlodipine single-pill combinations vs amlodipine monotherapy for superior blood pressure lowering and improved tolerability in patients with uncontrolled hypertension: results of the TEAMSTA-5 study. 61
21762357 2011
49
Increased serum S-100B and neuron specific enolase - Potential markers of early nervous system involvement in essential hypertension. 61
21130083 2011
50
Do we need a pulmonary artery catheter in cardiac anesthesia? - An Indian perspective. 61
21196671 2011
51
Smokers are over-represented in subjects with ahaptoglobinemia in Ghana. 61
20720373 2010
52
Increased potassium intake from fruit and vegetables or supplements does not lower blood pressure or improve vascular function in UK men and women with early hypertension: a randomised controlled trial. 61
20673378 2010
53
Pregnancy outcome in eclamptics at the University of Abuja Teaching Hospital, Gwagwalada, Abuja: a 3 year review. 61
21220852 2010
54
Diastolic dysfunction predicts new-onset atrial fibrillation and cardiovascular events in patients with acute myocardial infarction and depressed left ventricular systolic function: a CARISMA substudy. 61
20304839 2010
55
Efficacy and safety of irbesartan/HCTZ in severe hypertension according to cardiometabolic factors. 61
20629810 2010
56
Obstructive sleep apnea and atrial fibrillation. 61
23616697 2010
57
Obesity-related cardiorenal syndrome. 61
20047633 2010
58
Effect of valsartan or olmesartan addition to amlodipine on ankle edema in hypertensive patients. 61
20174905 2010
59
Doppler-derived myocardial performance index in patients with impaired left ventricular relaxation and preserved systolic function. 61
19486117 2009
60
Effects of fixed-dose isosorbide dinitrate/hydralazine on diastolic function and exercise capacity in hypertension-induced diastolic heart failure. 61
19620510 2009
61
Endovascular revascularization of renal artery stenosis in the solitary functioning kidney. 61
19217744 2009
62
Fixed-dose manidipine/delapril versus losartan/hydrochlorothiazide in hypertensive patients with type 2 diabetes and microalbuminuria. 61
19330493 2009
63
Reference values for cardiopulmonary exercise testing in healthy volunteers: the SHIP study. 61
18768575 2009
64
Hypertension in an urban HIV-positive population compared with the general population: influence of combination antiretroviral therapy. 61
18854751 2008
65
The long-term outcomes of percutaneous therapy for renal artery fibromuscular dysplasia. 61
18692345 2008
66
Dilated cardiomyopathy in children and adults: what is new? 61
18690380 2008
67
Antihypertensive effect of zofenopril plus hydrochlorothiazide versus zofenopril monotherapy in patients with essential hypertension according to their cardiovascular risk level: A post hoc analysis. 61
24692801 2008
68
[Oral inhibitors of renin and their potential use as therapeutic agents in treating hypertension]. 54
18693632 2008
69
Efficacy and safety profiles of a new S(-)-amlodipine nicotinate formulation versus racemic amlodipine besylate in adult Korean patients with mild to moderate hypertension: an 8-week, multicenter, randomized, double-blind, double-dummy, parallel-group, phase III, noninferiority clinical trial. 61
18555932 2008
70
Development of a nomogram to predict occurrence of preeclampsia. 61
17669579 2008
71
Blood pressure is associated with cognitive impairment in young hypertensives. 61
17853255 2008
72
Evaluation of aortic stiffness in children with chronic renal failure. 61
17710441 2007
73
Inhibition of renin-angiotensin system and advanced glycation end products formation: a promising therapeutic approach targeting on cardiovascular diseases. 61
17979687 2007
74
Antihypertensive efficacy of zofenopril plus hydrochlorothiazide fixed combination for treatment in metabolic syndrome. 61
18029326 2007
75
Metabolic and antihypertensive effects of moxonidine and moxonidine plus irbesartan in patients with type 2 diabetes mellitus and mild hypertension: a sequential, randomized, double-blind clinical trial. 61
17617283 2007
76
Association of ACE genotype and predominantly diastolic hypertension: a preliminary study. 54
17487825 2007
77
Pharmacodynamic Effects of an Angiotensin II Receptor-Antagonist in Phase I-Comparison between Healthy Subjects and Patients with Hypertension. 61
19662194 2007
78
Effect on the development of ankle edema of adding delapril to manidipine in patients with mild to moderate essential hypertension: a three-way crossover study. 61
17577462 2007
79
Antibodies of IgM subclass to phosphorylcholine and oxidized LDL are protective factors for atherosclerosis in patients with hypertension. 61
16307748 2006
80
The 2006 Canadian Hypertension Education Program recommendations for the management of hypertension: Part II - Therapy. 54
16755313 2006
81
A placebo-controlled comparison of the efficacy and tolerability of candesartan cilexetil, 8 mg, and losartan, 50 mg, as monotherapy in patients with essential hypertension, using 36-h ambulatory blood pressure monitoring. 61
16620350 2006
82
An open-label, randomized, controlled, 4-week comparative clinical trial of barnidipine hydrochloride, a calcium-channel blocker, and benazepril, an angiotensin-converting enzyme inhibitor, in Chinese patients with renal parenchymal hypertension. 61
16749407 2006
83
Left atrial volume, geometry, and function in systolic and diastolic heart failure of persons > or =65 years of age (the cardiovascular health study). 61
16377289 2006
84
The importance of 24 hour ambulatory blood pressure monitoring after thoracic organ transplantation. 61
16297780 2005
85
New-onset cardiovascular risk factors in lung transplant recipients. 61
16210127 2005
86
Felodipine-metoprolol combination tablet: maintained health-related quality of life in the presence of substantial blood pressure reduction. 61
16202854 2005
87
Effect of successful hypertension control by manidipine or lisinopril on albuminuria and left ventricular mass in diabetic hypertensive patients with microalbuminuria. 61
16021438 2005
88
[Actual condition of alcohol intake and its effects on lifestyle-related disease in health checkup]. 61
16038425 2005
89
The 2005 Canadian Hypertension Education Program recommendations for the management of hypertension: part II - therapy. 54
16003449 2005
90
Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients. 61
16097363 2005
91
Early age-related maculopathy and risk factors of cardiovascular disease in middle-aged Lithuanian urban population. 61
15812769 2005
92
Manidipine versus enalapril monotherapy in patients with hypertension and type 2 diabetes mellitus: a multicenter, randomized, double-blind, 24-week study. 61
15811479 2005
93
Comparison of the efficacy and tolerability of telmisartan 40 mg vs. enalapril 10 mg in the treatment of mild-to-moderate hypertension: a multicentre, double-blind study in Taiwanese patients. 61
15617456 2004
94
Prevalence of hypertension, hypercholesterolemia, smoking and overweight in older Belgian adolescents. 61
15542870 2004
95
Maternal blood pressure in pregnancy, birth weight, and perinatal mortality in first births: prospective study. 61
15561733 2004
96
Heart failure in women. 61
15331319 2004
97
Effect of amlodipine-atorvastatin combination on fibrinolysis in hypertensive hypercholesterolemic patients with insulin resistance. 61
15363826 2004
98
Effects of telmisartan compared with eprosartan on blood pressure control, glucose metabolism and lipid profile in hypertensive, type 2 diabetic patients: a randomized, double-blind, placebo-controlled 12-month study. 61
15302981 2004
99
Advanced glycation end product cross-linking: pathophysiologic role and therapeutic target in cardiovascular disease. 61
15184729 2004
100
The beta1 subunit of the Ca2+-sensitive K+ channel protects against hypertension. 54
15057299 2004
101
Serum cholesterol levels, blood pressure response to stress and incidence of stable hypertension in young subjects with high normal blood pressure. 61
15076183 2004
102
Advanced glycation endproduct crosslinking in the cardiovascular system: potential therapeutic target for cardiovascular disease. 61
14977384 2004
103
Antiphospholipid antibodies and hypertension. 61
15540508 2004
104
The 2004 Canadian recommendations for the management of hypertension: Part II--Therapy. 54
14968142 2004
105
Effect of valsartan and atenolol on sexual behavior in hypertensive postmenopausal women. 61
14700518 2004
106
Efficacy and Safety of Valsartan 160mg/Hydrochlorothiazide 25mg Combination in Patients with Hypertension not Adequately Controlled by Valsartan 160mg/Hydrochlorothiazide 12.5mg. 61
17523721 2004
107
Circulating oxidized low-density lipoprotein is increased in hypertension. 61
12837127 2003
108
Diabetic autonomic neuropathy is associated with an increased incidence of strokes. 61
14614967 2003
109
Serum heat shock protein 70 levels predict the development of atherosclerosis in subjects with established hypertension. 61
12900429 2003
110
Comparative effect of lercanidipine, felodipine, and nifedipine GITS on blood pressure and heart rate in patients with mild to moderate arterial hypertension: the Lercanidipine in Adults (LEAD) Study. 61
12939564 2003
111
Distribution of risk factors in parents and siblings of patients with early coronary artery disease. 61
12856068 2003
112
[A1166C polymorphism of the angiotensin II type 1 receptor gene and essential hypertension in Han, Tibetan and Yi populations]. 61
12778448 2003
113
Systolic hypertension in hemodialysis patients. 61
12753679 2003
114
[Effect of atherogenic risk factors on the state of complex intima-media of common carotid artery]. 61
12891258 2003
115
Treatment of mild-to-moderate hypertension with calcium channel blockers: a multicentre comparison of once-daily nifedipine GITS with once-daily amlodipine. 61
12803737 2003
116
Cardiovascular physiology-changes with aging. 61
12502909 2003
117
A1166C polymorphism of the angiotensin II type 1 receptor gene and essential hypertension in Han, Tibetan and Yi populations. 61
12358135 2002
118
[Hypertension management in patients with stable coronary disease]. 61
12365075 2002
119
Isolated systolic hypertension is associated with adverse outcomes from coronary artery bypass grafting surgery. 61
11973166 2002
120
Losartan and perindopril effects on plasma plasminogen activator inhibitor-1 and fibrinogen in hypertensive type 2 diabetic patients. 61
11991216 2002
121
Factors influencing the systolic blood pressure response to drug therapy. 61
11821635 2002
122
Evaluation of the safety and efficacy of telmisartan and enalapril, with the potential addition of frusemide, in moderate-renal failure patients with mild-to-moderate hypertension. 61
11881131 2001
123
Sustained improvement of renal graft function for two years in hypertensive renal transplant recipients treated with nifedipine as compared to lisinopril. 61
11740389 2001
124
Cardiac and vascular remodeling in older adults with borderline isolated systolic hypertension: the ICARe Dicomano Study. 61
11751720 2001
125
Efficacy of nifedipine or lisinopril in the treatment of hypertension after renal transplantation: a double-blind randomised comparative trial. 61
11737121 2001
126
The effects of an ACE inhibitor and a calcium antagonist on the progression of renal disease: the Nephros Study. 61
11682661 2001
127
[Primary aldosteronism presented with intracranial hemorrhage]. 54
11681014 2001
128
Arterial compliance abnormalities in isolated systolic hypertension. 61
11710778 2001
129
Treatment with irbesartan or atenolol improves endothelial function in essential hypertension. 61
11593101 2001
130
A forced titration study of antihypertensive efficacy of candesartan cilexetil in comparison to losartan: CLAIM Study II. 61
11464257 2001
131
Reduction of left ventricular mass by lisinopril and nifedipine in hypertensive renal transplant recipients: a prospective randomized double-blind study. 61
11468543 2001
132
Systolic and pulse blood pressures (but not diastolic blood pressure and serum cholesterol) are associated with alterations in carotid intima-media thickness in the moderately hypercholesterolaemic hypertensive patients of the Plaque Hypertension Lipid Lowering Italian Study. PHYLLIS study group. 61
11204308 2001
133
Treatment of hypertension in patients > or =65 years of age: experience with amlodipine. 61
11192138 2000
134
Dose response and safety of telmisartan in patients with mild to moderate hypertension. 61
11185637 2000
135
Pilot study of combined blockade of the renin-angiotensin system in essential hypertensive patients. 61
10954007 2000
136
Strong and significant relationships between aggregation of major coronary risk factors and the acceleration of carotid atherosclerosis in the general population of a Japanese city: the Suita Study. 61
10927726 2000
137
Influence of diabetes and type of hypertension on response to antihypertensive treatment. 61
10818061 2000
138
Study of V(1)-vascular vasopressin receptor gene microsatellite polymorphisms in human essential hypertension. 61
10756113 2000
139
Evaluation of the aldosterone synthase (CYP11B2) gene polymorphism in patients with myocardial infarction. 61
10720582 2000
140
Pre-operative control of arterial hypertension using ketoconazole in pediatric patients with adrenocortical tumors. 61
10711667 2000
141
How do South African obstetricians manage hypertensive disorders of pregnancy--a survey. 61
10745971 2000
142
Isolated systolic hypertension; diastolic dysfunction. 61
10977448 2000
143
Elevated systolic blood pressure as a cardiovascular risk factor. 61
10955386 2000
144
Candesartan Cilexetil, a Novel Angiotensin II Type 1 (AT1) Receptor Blocker, Reduces Microalbuminuria in Patients with Type II Diabetes Mellitus and Mild Hypertension. 61
28425802 2000
145
Effects of a single dose of oral estrogen on left ventricular diastolic function in hypertensive postmenopausal women with diastolic dysfunction. 61
10632414 2000
146
Atorvastatin for the management of Type 2 diabetic patients with dyslipidaemia. A mid-term (9 months) treatment experience. 61
10782562 1999
147
Clinical implications of white coat hypertension: an ambulatory blood pressure monitoring study. 61
10618670 1999
148
Change in paternity: a risk factor for preeclampsia in multiparous women? 61
10660264 1999
149
Candesartan cilexetil in combination with low-dose hydrochlorothiazide is effective in severe hypertension. 61
10588093 1999
150
Felodipine-metoprolol combination tablet: a valuable option to initiate antihypertensive therapy? 61
10509550 1999
151
Perindopril 2mg/indapamide 0.625mg. Fixed low-dose combination. 61
10473021 1999
152
Nifedipine and arotinolol in combination for accelerated-malignant hypertension: results of one year follow-up. 61
10487322 1999
153
Can echocardiography identify mildly hypertensive patients at high risk, left untreated based on current guidelines? 61
10459880 1999
154
Essential arterial hypertension and stone disease. 61
10354288 1999
155
Diastolic dysfunction and baroreflex sensitivity in hypertension. 61
10334801 1999
156
Metabolic effects of temocapril in hypertensive patients with diabetes mellitus type 2. 61
10218721 1999
157
Beta-blocker effects on plasma lipids during prolonged treatment of hypertensive patients with hypercholesterolemia. 61
10218722 1999
158
[The role of nitric oxide and blood platelets in pathogenesis of preeclampsia]. 61
10390913 1999
159
[Clinical study of the month. The CAPPP study: "The Captopril Prevention Project"]. 61
10321112 1999
160
[New requirements in the primary treatment of arterial hypertension: why do we need fixed low-dose combination therapy?]. 61
10189913 1999
161
Is initial dose titration of amlodipine worthwhile in patients with mild to moderate hypertension? 61
10216810 1999
162
[A critical analysis of the Hypertension Optimal Treatment (HOT) Study (appeared in Lancet 1998; 351: 1755-1762)]. 61
10721156 1999
163
Candesartan cilexetil in hypertension: effects of six weeks' treatment on haemodynamics, baroreceptor sensitivity and the renin-angiotensin-aldosterone system. 61
10697305 1999
164
Double-blind, randomized, multicentre comparison of the effects of amlodipine and perindopril on 24 h therapeutic coverage and beyond in patients with mild to moderate hypertension. General Physicians Investigators' Group. 61
10100105 1999
165
Quality of life and calcium channel blockade with nifedipine GITS versus amlodipine in hypertensive patients in Spain. Gastrointestinal Therapeutic System. 61
9869019 1998
166
Different effects of nifedipine and amlodipine on circulating catecholamine levels in essential hypertensive patients. 61
9856375 1998
167
Amlodipine, felodipine, and isradipine in the treatment of Chinese patients with mild-to-moderate hypertension. 61
9916609 1998
168
Differences among geriatricians, general internists, and cardiologists in the care of patients with heart failure: a cautionary tale of quality assessment. 61
9809755 1998
169
[Types of hypertension in pregnant women of Benin admitted to the National University Hospital of Cotonou]. 61
9854012 1998
170
Acute effects of candesartan cilexetil (the new angiotensin II antagonist) on systemic and renal haemodynamics in hypertensive patients. 61
9832289 1998
171
Bisoprolol in the treatment of hypertension in the elderly. 61
9783498 1998
172
Different effects of nifedipine and amlodipine on circulating catecholamine levels in essential hypertensive patients. 61
9746123 1998
173
Effect of single-drug therapy on reduction of left atrial size in mild to moderate hypertension: comparison of six antihypertensive agents. 61
9679720 1998
174
Acute hypertension impairs endothelium-dependent vasodilation. 61
9854457 1998
175
Effects of amlodipine and lisinopril on left ventricular mass and diastolic function in previously untreated patients with mild to moderate diastolic hypertension. 54
9657538 1998
176
The prevalence of silent myocardial ischaemia in patients with white-coat hypertension. 61
9655656 1998
177
Effect of enalapril therapy on ventilatory pulmonary function tests in hypertensive patients. 61
11273316 1998
178
Accuracy of noninvasive oxyhemoglobin saturation, end-tidal carbon dioxide concentration, and blood pressure monitoring during experimentally induced hypoxemia, hypotension, or hypertension in anesthetized dogs. 61
9492938 1998
179
Ligation of medically refracted patent ductus arteriosus (PDA) in an extremely low body weight premature infant. 61
9872552 1998
180
Efficacy and tolerability of amlodipine in the general practice treatment of essential hypertension in an asian multinational population. 61
18370538 1998
181
Health status of senior civil servants in Kuala Lumpur. 61
10968112 1997
182
Posttransplant diastolic hypertension: associations with intragraft transforming growth factor-beta, endothelin, and renin transcription. 54
9422408 1997
183
Risk factors associated with preeclampsia in healthy nulliparous women. The Calcium for Preeclampsia Prevention (CPEP) Study Group. 61
9396883 1997
184
[Behavior of arterial blood pressure in patients with cerebrovascular diseases]. 61
9462982 1997
185
Patterns of compliance with once versus twice daily antihypertensive drug therapy in primary care: a randomized clinical trial using electronic monitoring. 61
9374947 1997
186
Randomised, double blind, multicentre comparison of hydrochlorothiazide, atenolol, nitrendipine, and enalapril in antihypertensive treatment: results of the HANE study. HANE Trial Research Group. 61
9251545 1997
187
Fixed-dose combination therapy with trandolapril and verapamil SR is effective in primary hypertension. Trandolapril Study Group. 54
9231890 1997
188
Felodipine use in pregnancy. Report of three cases. 61
9219129 1997
189
Efficacy of combination therapy with trandolapril and verapamil sr in primary hypertension: a 4 x 4 trial design. The Trandolapril Study Group. 54
9107443 1997
190
Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. 61
9133508 1997
191
[Ambulatory monitoring of arterial pressure in the treatment of mild-moderate arterial hypertension with lisinopril vs. enalapril]. 61
9221708 1997
192
Hemodynamics in white coat hypertension compared to ambulatory hypertension and normotension. 61
8931834 1996
193
Re-examining the clinical safety and roles of calcium antagonists in cardiovascular medicine. 61
8903280 1996
194
Screening for abdominal aortic aneurysms in a hypertensive patient population. 61
8862100 1996
195
Urapidil treatment decreases plasma fibrinogen concentration in essential hypertension. 61
8843176 1996
196
Missed opportunities for the prevention of cardiovascular disease among British hypertensives in primary care. 61
8945793 1996
197
Regression of left ventricular hypertrophy in experimental renovascular hypertension: diastolic dysfunction depends more on myocardial collagen than it does on myocardial mass. 61
8986913 1996
198
Nitrendipine and enalapril in the treatment of diabetic hypertensive patients with microalbuminuria. 61
8743519 1996
199
Effect of the ACE inhibitor ceronapril on cerebral blood flow in hypertensive patients. 61
8792940 1996
200
[Antihypertensive effect and adverse effects of isradipine in patients with sever hypertension. Results of an open multicenter study]. 61
8767350 1996
201
Long-term effects on plasma lipids of diet and drugs to treat hypertension. Treatment of Mild Hypertension Study (TOMHS) Research Group. 61
8622245 1996
202
Prediction of the left ventricular mass from the electrocardiogram in systemic hypertension. 61
8644648 1996
203
Factors associated with the development of stable hypertension in young borderline hypertensives. 61
8761902 1996
204
Perinatal morbidity in chronic hypertension. 61
8616127 1996
205
[Endomyocardial fibrosis (its clinico-echocardiographic characteristics)]. 61
9005618 1996
206
Oral therapy with combined enalapril, prazosin and hydrochlorothiazide in the acute treatment of severe hypertension in Nigerians. 61
8880050 1996
207
Quality of life in hypertensive patients treated with either carvedilol or enalapril. 61
8777472 1996
208
Hypertension and left ventricular hypertrophy. 61
8742911 1996
209
Omega-3 polyunsaturated fatty acid supplements and ambulatory blood pressure monitoring parameters in patients with mild essential hypertension. 61
8903660 1995
210
Combined treatment with captopril, hydrochlorothiazide and pravastatin in dyslipidemic hypertensive patients. 61
8746603 1995
211
Comparative efficacy of two long-acting formulations of nifedipine in the treatment of hypertension. The Switch Study Investigators. 61
7489530 1995
212
[Comparison of blood pressure profile during exercise with benazepril 10 mg and benazepril 5 mg/hydrochlorothiazide 6.25 mg fixed combination]. 61
7482386 1995
213
Comparative evaluation of the antihypertensive efficacy of once-daily sustained-release isradipine and lacidipine using 24-hour ambulatory blood-pressure monitoring. 61
7589766 1995
214
Different hemodynamic effects of celipropol and atenolol in patients with mild to moderate hypertension. 61
8573224 1995
215
[Efficacy and tolerability of the captopril and hydrochlorothiazide combination in the treatment of mild to moderate hypertension. Multicenter study]. 61
8561680 1995
216
Angiotensin-converting enzyme gene polymorphism has no influence on the circulating renin-angiotensin-aldosterone system or blood pressure in normotensive subjects. 54
7796503 1995
217
Platelet function and fibrinolytic activity during rest and exercise in borderline hypertensive patients. 61
7601202 1995
218
[Hypertension diagnosis by the family physician: measurements according to the NHG-standard (Dutch College of General Practitioners) compared with ambulatory blood pressure determination]. 61
7862217 1995
219
Contrasting effects of angiotensin converting inhibitor and alpha-1-antagonist on albuminuria in insulin-dependent diabetes mellitus patients with nephropathy. 61
7830033 1995
220
Carotid intima-media thickness and plaque in borderline hypertension. 61
7839394 1995
221
Urinary albumin and N-acetyl-beta-D-glucosaminidase excretions in mild hypertension. 61
7848623 1994
222
Dyslipoproteinemic changes in borderline hypertension. 61
7960021 1994
223
Diabetic cardiomyopathy: experimental and clinical observations. 61
7808691 1994
224
[Stenotic-obliterative carotid lesions and arterial hypertension. An analysis of 16,379 subjects from the OPI program. Obiettivo Prevenzione Ictus]. 61
7816234 1994
225
Increased basal concentrations of plasma endothelin in borderline hypertension. 61
7852751 1994
226
[Baroreceptor reflex function in young normotensive men with a family history of hypertension]. 61
7933653 1994
227
A large, prospective, open-label study of isradipine in patients with essential hypertension. The Isradipine Investigators Group. 61
7982252 1994
228
A comparison of intravenous nicardipine and sodium nitroprusside in the immediate treatment of severe hypertension. 61
7946164 1994
229
Reduction of left ventricular mass by short-term antihypertensive treatment with isradipine: a double-blind comparison with enalapril. 61
7921533 1994
230
[Treatment of mild and moderate hypertension with fosinopril. Comparison of adverse effects with other antihypertensive agents]. 61
7998871 1994
231
[Possible influence of hemodynamic and neurohormonal factors on the heart's response to arterial hypertension]. 61
8062298 1994
232
Maximal vascular conductance in right ventricular myocardial circulation. 61
8184914 1994
233
Quinapril hydrochloride effects on renal function in patients with renal dysfunction and hypertension: a drug-withdrawal study. 61
7918140 1994
234
[Renal insufficiency in arterial hypertension in black Africa]. 61
8078835 1994
235
[Comparative and double-blind study of the efficacy and safety of cilazapril compared to nifedipine retard in the treatment of mild and moderate arterial hypertension]. 61
7980076 1994
236
[Excretion of beta-2-microglobulin in hypertension]. 61
7862587 1994
237
Hemodynamic effects of 3,4-diaminopyridine in a swine model of verapamil toxicity. 61
8135425 1994
238
High-dose epinephrine results in greater early mortality after resuscitation from prolonged cardiac arrest in pigs: a prospective, randomized study. 61
8306688 1994
239
Ambulatory blood pressure in normotensive and hypertensive subjects: results from an international database. 61
7769499 1994
240
The 24-hour efficacy of a new once-daily formulation of nifedipine. Italian Nifedipine GITS Study Group. 61
7533703 1994
241
Single daily administration of spirapril in the treatment of essential hypertension. A multicentre double-blind comparison of 1, 6, 12 and 24 mg of spirapril once daily. 61
8061845 1994
242
24-hour ambulatory blood pressure monitoring and spirapril in mild to severe essential hypertension: a randomized dose comparison. 61
8061842 1994
243
Hypertension and silent myocardial ischemia: their influence on cardiovascular mortality and morbidity. 61
7736483 1994
244
Short report: ambulatory blood pressure in normotensive compared with hypertensive subjects. The Ad-Hoc Working Group. 61
8301112 1993
245
Conversion from sustained-release to immediate-release calcium entry blockers: outcome in patients with mild-to-moderate hypertension. 61
8111798 1993
246
The association between hypertension and sleep apnea in obese patients. 61
8365288 1993
247
The incidence of first-dose hypotension with quinapril in patients with mild to moderate hypertension. 61
8292465 1993
248
[Experience with amlodipine (Norvasc) in the management of arterial hypertension]. 61
8146352 1993
249
[The diagnostic confirmation of mild arterial hypertension via ambulatory monitoring]. 61
8374017 1993
250
Large prospective study of ramipril in patients with hypertension. CARE Investigators. 61
8269447 1993
251
Sex differences in cardiac adaptation to isolated systolic hypertension. 61
8342510 1993
252
[Hypertension in patients with post-streptococcal glomerulonephritis]. 61
8273303 1993
253
Can garlic lower blood pressure? A pilot study. 61
8361870 1993
254
Sublingual nifedipine and captopril in hypertensive urgencies and emergencies. 61
8314271 1993
255
Clinical features of benign hypertensive nephrosclerosis at time of renal biopsy. 61
8327642 1993
256
Low-dose aspirin in prevention and treatment of intrauterine growth retardation and pregnancy-induced hypertension. Italian study of aspirin in pregnancy. 61
8094168 1993
257
A double-blind comparison of the effects of carvedilol and captopril on serum lipid concentrations in patients with mild to moderate essential hypertension and dyslipidaemia. 61
8223847 1993
258
[24-hour effect and tolerance for perindopril (Prestarium) in mild and moderate essential hypertension]. 61
1494869 1992
259
Factors associated with hypertension in Nigerian civil servants. 61
1438117 1992
260
Clinical prognostic factors in lupus nephritis. The importance of hypertension and smoking. 61
1417382 1992
261
Neuropeptide Y-like immunoreactivity and hypertension. 61
1335004 1992
262
Relationship between insulin sensitivity and degree of obesity in mild hypertension. 61
1415317 1992
263
Resting blood pressure and cardiovascular response to sympathetic stimulation in adolescents. 61
1512058 1992
264
Acetylation status using hydralazine in African hypertensives at Kenyatta National Hospital. 61
1396201 1992
265
[Slow release diltiazem as monotherapy in primary mild to moderate hypertension. A multicenter study]. 61
1340718 1992
266
Serial changes in blood pressure from adolescence into adulthood. 61
1632426 1992
267
Endothelin-induced venoconstriction is unaffected by type 2-diabetes: in vivo effect of histamine on the endothelin action on veins. 61
1530376 1992
268
Candoxatril, an orally active neutral endopeptidase inhibitor, raises plasma atrial natriuretic factor and is natriuretic in essential hypertension. 61
1315825 1992
269
Enalapril monotherapy in essential hypertension. 61
1629142 1992
270
Nitrendipine in the therapeutic management of elderly hypertensive patients: results of a multicenter trial. Andalousian Hypertension Group. 61
1377302 1992
271
Flow resistance and its components in hypertensive men treated with the calcium antagonist isradipine. 61
1483483 1992
272
Protection: risk ratio of antihypertensive drug treatment in the elderly. 61
1590663 1992
273
Could CAPD modulate the hemodynamic changes induced by rHuEPO treatment? 61
1361842 1992
274
Effect of antihypertensive treatment with nitrendipine on left ventricular mass and diastolic filling in patients with mild to moderate hypertension. 61
1375682 1992
275
Caffeine restriction: effect on mild hypertension. 61
1747643 1991
276
Blood pressure in hemodialysis patients during amelioration of anemia with erythropoietin. 61
1751794 1991
277
Opportunities to improve the cost-effectiveness of treatment for hypertension. 61
1909687 1991
278
Correlations between left ventricular mass and systolic blood pressure at rest and during maximal exercise in moderately hypertensive men. 61
1920338 1991
279
A parallel group randomised comparative study of felodipine and nifedipine in hypertension. 61
1800302 1991
280
[Doppler analysis of mitral flow in mild to moderate hypertension]. 61
1852962 1991
281
Coronary risk factors six to twelve months after coronary artery bypass surgery. 1986 compared with 1990. 61
1888353 1991
282
The cost-effectiveness of treating mild-to-moderate hypertension: a reappraisal. 61
1851782 1991
283
Effect of drug and diet treatment of mild hypertension on diastolic blood pressure. The TAIM Research Group. 61
1671380 1991
284
A comparison of Chinese traditional and Western medical approaches for the treatment of mild hypertension. 61
1897264 1991
285
Treatment of mild-to-moderate hypertension: comparison between a calcium-channel blocker and a potassium-sparing diuretic. 61
1725543 1991
286
Optimising drug management of individuals with cryptogenic hypertension. 61
2029155 1991
287
[The results of the comparative study of nadolol, propranolol, prazosin and hydrochlorothiazide in patients with arterial hypertension in a 12-month stepped-plan treatment (cooperative research). The Working Group of the Cooperative Program to Study New Preparations in the Prevention of Arterial Hypertension. I. The research protocol and results of monotherapy]. 61
1792612 1991
288
The results of the comparative study of nadolol, propranolol, prazosin and hydrochlorothiazide in patients with arterial hypertension in a 12-month stepped-plan treatment (cooperative research). The Working Group of the Cooperative Program to Study New Preparations in the Prevention of Arterial Hypertension. II. The results of combined therapy. Side effects. The reasons for dropouts. Conclusion. 61
1792613 1991
289
Left ventricular diastolic dysfunction in patients with congestive heart failure. 61
1994065 1991
290
Long-term antihypertensive treatment with lacidipine, a new long-acting calcium antagonist. 61
1725446 1991
291
[Treatment of hypertension in arteritic patients]. 61
1791378 1991
292
A double-blind comparative study of doxazosin and prazosin when administered with beta-blockers or diuretics. 61
1670744 1991
293
Treatable complications in undiagnosed cases of autosomal dominant polycystic kidney disease. 61
1670785 1991
294
A double-blind comparison of the efficacy and safety of lacidipine with atenolol in the treatment of essential hypertension. The United Kingdom Lacidipine Study Group. 61
1726002 1991
295
Exercise and mild essential hypertension. Recommendations for adults. 61
2291033 1990
296
Sustained calcium channel blockade in the treatment of severe hypertension. A two year experience. 61
1964056 1990
297
Use of quinapril in the elderly patient. 61
2261146 1990
298
[Spirapril and nitrendipine in arterial hypertension. A comparison of therapeutic effects and tolerance]. 61
2238185 1990
299
[Clinical-instrumental evaluation of the effects of quinapril treatment in mild-to-moderate hypertension]. 61
2149311 1990
300
Efficacy of potassium and magnesium in essential hypertension: a double-blind, placebo controlled, crossover study. 61
2207419 1990
301
A comparison of the efficacy and safety of a beta-blocker, a calcium channel blocker, and a converting enzyme inhibitor in hypertensive blacks. 61
2200382 1990
302
Prevalence, awareness & treatment status of hypertension in urban population of Delhi. 61
2228067 1990
303
Cerebral blood flow during the acute therapy of severe hypertension with oral clonidine. 61
2363750 1990
304
Hypertension control in Harare municipal clinics. 61
2272087 1990
305
[Echocardiographic control of treatment of mild hypertension with trimepranol]. 61
1978953 1990
306
Spironolactone and altizide versus converting enzyme inhibitor (enalapril). 61
2191586 1990
307
Clinical update: spironolactone and altizide as monotherapy in systemic hypertension. 61
2191585 1990
308
Quality of life on antihypertensive therapy: a randomized double-blind controlled trial of captopril and atenolol. 61
2163421 1990
309
[Role of a beta adrenergic blocking agent nadolol (corgard) in prevention of arterial hypertension: a 6-month treatment (cooperative study)]. 61
2202853 1990
310
Assessment of intravenous fenoldopam mesylate in the management of severe systemic hypertension. 61
1970283 1990
311
[A computerized support system for the ambulatory treatment of patients with arterial hypertension]. 61
2197159 1990
312
Screening and surveillance of pregnancy hypertension--an economic approach to the use of daycare. 61
2119266 1990
313
Isolated systolic hypertension: does it really exist on ambulatory blood pressure monitoring? 61
2340642 1990
314
Verapamil but not nifedipine impairs left ventricular function during exercise in hypertensive patients. 61
2309606 1990
315
[Efficacy and tolerance of a new calcium-channel blocking agent (nitrendipine) in the treatment of arterial hypertension]. 61
2288512 1990
316
Left ventricular hypertrophy and impaired diastolic filling in essential hypertension. Diastolic mechanisms for systolic dysfunction during exercise. 61
2137735 1990
317
[The significance of cGMP and dopamine receptor on the natriuretic and hypotensive activities of synthetic atrial natriuretic polypeptide in essential hypertension]. 61
2158911 1990
318
Pulsatile flow and oscillating wall shear stress in the brachial artery of normotensive and hypertensive subjects. 61
2328518 1990
319
Efficacy and safety of carvedilol in comparison with atenolol in hypertensive patients pretreated with hydrochlorothiazide. 61
1974506 1990
320
Effects of sustained-release diltiazem on blood pressure and serum lipids: a multicenter, randomized, placebo-controlled study. 61
1706012 1990
321
The calcium antagonist isradipine in the therapy of hypertension. A double-blind crossover comparison with nifedipine. 61
2150644 1990
322
Treating mild to moderate hypertension: cost-effectiveness and policy implications. 61
1708013 1990
323
Effect of bisoprolol and acebutolol on resting blood pressure and on exercise blood pressure profile in hypertensive patients: a comparative, single-blind study. 61
11527124 1990
324
[Hypertension in the aged person. Numerous questions, few responses]. 61
2090962 1990
325
Prognostic factors in malignant hypertension selected by multivariate analysis. 61
23275987 1990
326
Antihypertensive effects of tertatolol. A comparative study versus atenolol. 61
2573377 1989
327
Diltiazem as monotherapy in treatment of mild to moderate essential hypertension. 61
2699494 1989
328
Effort blood pressure control in the course of antihypertensive treatment. 61
2782327 1989
329
Five years experience of haemodialysis at the Lagos University Teaching Hospital--November 1981 to November 1986. 61
2551160 1989
330
Predictive value of increased plasma levels of fibronectin in gestational hypertension. 61
2504045 1989
331
Hypertension registers in general practice: levels of control and nondrug management. 61
2761880 1989
332
Controlled clinical trials of drug treatment for hypertension. A review. 61
2490827 1989
333
South Birmingham Coronary Prevention Project: a district approach to the prevention of heart disease. 61
2752725 1989
334
A multicenter evaluation of the safety, tolerability, and efficacy of isradipine in the treatment of essential hypertension. 61
2523665 1989
335
New insights and new approaches for the treatment of essential hypertension: selection of therapy based on coronary heart disease risk factor analysis, hemodynamic profiles, quality of life, and subsets of hypertension. 61
2648781 1989
336
Sensitivity to insulin during treatment with atenolol and metoprolol: a randomised, double blind study of effects on carbohydrate and lipoprotein metabolism in hypertensive patients. 61
2500169 1989
337
Sex steroid hormones are altered in essential hypertension. 61
2523421 1989
338
Trial of antihypertensive interventions and management. Design, methods, and selected baseline results. 61
2649308 1989
339
Stability of renal allograft function associated with long-term cyclosporine immunosuppressive therapy--five year follow-up. 61
2645711 1989
340
Management of hypertension in actively exercising patients. Implications for drug selection. 61
2649357 1989
341
Effect of diltiazem on left ventricular mass and diastolic filling in mild to moderate hypertension. 61
2642633 1989
342
Bopindolol in the treatment of hypertension: a double blind study comparing bopindolol and metoprolol. 61
2575480 1989
343
The benefits of treating mild to moderate hypertension. A quantitative estimation of the life expectancy gains from pharmacological reduction of blood pressure. 61
2506315 1989
344
Blood pressure load--a better determinant of hypertension. 61
3193818 1988
345
University of California, Davis, conference: Mild hypertension. 61
3055978 1988
346
Comparison of antihypertensive efficacy and perinatal safety of labetalol and methyldopa in the treatment of hypertension in pregnancy: a randomized controlled trial. 61
3056503 1988
347
Renal effects of fenoldopam in refractory hypertension. 61
2903190 1988
348
Efficacy and safety of cilazapril, a new angiotensin-converting enzyme inhibitor. 61
2970856 1988
349
The atrial natriuretic factor in hypertension. 61
2966581 1988
350
Short-term behavioral effects of beta-adrenergic medications in men with mild hypertension. 61
3356086 1988
351
Efficacy and safety of rilmenidine for arterial hypertension. 61
2894168 1988
352
Nitrendipine monotherapy in severe hypertension. 61
3341610 1988
353
Hypertension therapy: current and future strategies. 61
3065098 1988
354
Analysis of well-being and 24-hour blood pressure recording in a comparative study between indapamide and captopril. 61
3277419 1988
355
[Prolonged treatment of hypertension in diabetic patients with enalapril. 1-year follow-up]. 61
2825079 1987
356
Beta-blockers versus diuretics in hypertensive men: main results from the HAPPHY trial. 61
2892881 1987
357
Anesthesia and hypertension: the effect of clonidine on perioperative hemodynamics and isoflurane requirements. 61
3605732 1987
358
Reversible hypertension associated with unrecognised high pressure chronic retention of urine. 61
2883394 1987
359
Relaxation training for essential hypertension at the worksite: I. The untreated mild hypertensive. 61
3299442 1987
360
Use of nuclear magnetic resonance imaging to show regression of hypertrophy with ramipril treatment. 61
3034042 1987
361
Enalapril as first choice treatment of mild, moderate and severe essential hypertension: results of an open multicentre clinical trial. New Zealand Hypertension Study Group. 61
2837697 1987
362
[Potentiation of the hypotensive effect of labetalol in hypertensive patients treated to maintain sodium balance in the body]. 61
3573527 1987
363
Treatment of severe hypertension with peroral labetalol. 61
3590400 1987
364
Treatment of high blood pressure in overweight patients. 61
2962005 1987
365
Effects of intravenous ketanserin on severely hypertensive patients with double-blind crossover assessment of central side-effects. 61
2434787 1987
366
[Hypertension management in practice, 1986]. 61
2878492 1986
367
Comparison of bevantolol and atenolol for systemic hypertension. 61
2878597 1986
368
Course of blood pressure in mild hypertensives after withdrawal of long term antihypertensive treatment. Medical Research Council Working Party on Mild Hypertension. 61
2876745 1986
369
Relations between erythrocyte lithium efflux, blood pressure and family histories of hypertension and cardiovascular disease: studies in a factory workforce and hypertension clinic. 61
3794334 1986
370
Strokes in mild hypertension: diastolic rules. 61
2876293 1986
371
Financial cost as an obstacle to hypertension therapy. 61
3740334 1986
372
Role of diuretics in treatment of essential hypertension. 61
3524184 1986
373
[Therapeutic use of lowering blood pressure, especially in mild hypertension. Results of a hypertension detection and treatment program]. 61
3765731 1986
374
Characteristics of blood flow velocity in the hypertensive canine pulmonary artery. 61
3521028 1986
375
Effects of two antihypertensive agents on lipids, lipoproteins, and apoproteins A and B. Comparison of prazosin and atenolol. 61
3511689 1986
376
Comparative hypotensive effects of acebutolol and hydrochlorothiazide in patients with mild to moderate essential hypertension: a double-blind multicenter evaluation. 61
3511650 1986
377
Reversibility of cerebral symptoms in severe hypertension in relation to acute antihypertensive therapy. Danish Multicenter Study. 61
3532694 1986
378
Antihypertensive effect of indapamide given in conjunction with captopril in severe hypertension. 61
3545687 1986
379
Effect of a high carbohydrate, low sodium and low fat diet in type 2 diabetics with moderate hypertension. 61
3011689 1986
380
Transdermal clonidine therapy in elderly mild hypertensives: effects on blood pressure, plasma norepinephrine and fasting plasma glucose. 61
3868715 1985
381
Evaluation and management of childhood hypertension. 61
4071363 1985
382
Is insulin the link between hypertension and obesity? 61
3908323 1985
383
The influence of food intake on pharmacodynamics and plasma concentration of captopril. 61
3910768 1985
384
Increased renal reabsorption of inorganic sulfate in third-trimester high-risk pregnancies. 61
4047539 1985
385
Cardiovascular risk and risk factors in a randomized trial of treatment based on the beta-blocker oxprenolol: the International Prospective Primary Prevention Study in Hypertension (IPPPSH). The IPPPSH Collaborative Group. 61
2864374 1985
386
[Controlled study on the treatment of hypertension with verapamil in retard form]. 61
3901562 1985
387
Need to prevent and control high-normal and high blood pressure, particularly so-called "mild" hypertension: epidemiological and clinical data. 61
3877923 1985
388
Comparison of weight reduction with metoprolol in treatment of hypertension in young overweight patients. 61
2860441 1985
389
Comparison of acebutolol and hydrochlorothiazide in essential hypertension. 61
2859781 1985
390
Once-daily acebutolol and atenolol in essential hypertension: double-blind crossover comparison. 61
3993534 1985
391
Effects of drug therapy on hypertensive left ventricular hypertrophy. 61
3161673 1985
392
A randomized controlled trial of weight reduction and metoprolol in the treatment of hypertension in young overweight patients. 61
3896595 1985
393
Detection and treatment of hypertension in older individuals. 61
4014126 1985
394
Overweight and obesity in hypertension. 61
3991876 1985
395
Comparison of acebutolol and propranolol in essential hypertension. 61
3880995 1985
396
The relationship between blood lead levels and blood pressure and its cardiovascular risk implications. 61
4014119 1985
397
Mild Hypertension: Should it be Treated? 61
21274101 1985
398
[Treatment of hypertension in the diabetic with captopril]. 61
3883242 1985
399
Effects of a lack of aortic "Windkessel" properties on the left ventricle. 61
2857795 1985
400
The case for treating mild hypertension. 61
2580160 1985
401
Muzolimine and nitrendipine in the treatment of arterial hypertension. 61
3159163 1985
402
[Comparative study of the effects of prazosin and atenolol on plasma lipids of hypertensive patients]. 61
3890049 1985
403
Blood pressure lowering and potassium conservation by triamterene-hydrochlorothiazide and amiloride-hydrochlorothiazide in hypertension. 61
3880686 1985
404
Antihypertensive efficacy and tolerance of penbutolol: results of a co-operative study in 227 patients. 61
3886307 1985
405
Hydrochlorothiazide and potassium chloride in comparison with hydrochlorothiazide and amiloride in the treatment of mild hypertension. 61
3911735 1985
406
Antihypertensive efficacy of two low dosages of hydrochlorothiazide in patients treated with captopril. 61
3907843 1985
407
Low-dose captopril for the treatment of mild to moderate hypertension. I. Results of a 14-week trial. Veterans Administration Cooperative Study Group on Antihypertensive Agents. 61
6237623 1984
408
Correlation between lymphocyte beta 2-adrenoceptor density and mean arterial blood pressure: elevated beta-adrenoceptors in essential hypertension. 61
6206325 1984
409
Step-down treatment of mild systemic hypertension. 61
6711432 1984
410
Peripheral renal vascular disease in essential hypertension: hemodynamic, angiographic, and endocrine assessment. 61
6388838 1984
411
Comparison of blood pressure, plasma lipid and cardiac performance responses to prazosin versus propranolol in thiazide-treated hypertensive patients. 61
6364760 1984
412
Long-term antihypertensive therapy with captopril. 61
6354930 1983
413
Comparison of intramuscularly and intravenously administered clonidine in the treatment of severe hypertension. 61
6678385 1983
414
[Electro- and phonocardiographic diagnosis of interatrial septal defect and pulmonary hypertension in patients over 20 years old]. 61
6620841 1983
415
Prazosin and oxprenolol therapy in pregnancy hypertension. 61
6879369 1983
416
Pregnancy outcome in 211 patients with mild chronic hypertension. 61
6835611 1983
417
Hypertension: prevalence, risks, and effect of therapy. 61
6847007 1983
418
[Treatment of accelerated arterial or malignant hypertension with captopril. Value, efficacy and outcome of visceral complications]. 61
6351694 1983
419
Propranolol-hydralazine combination in essential hypertension. 61
6352036 1983
420
Relation of arterial pressure with body sodium, body potassium and plasma potassium in essential hypertension. 61
7047050 1982
421
Hypertension treated by sodium restriction. 61
7033744 1981
422
Treatment of mild hypertension in the elderly. A study initiated and administered by the National Heart Foundation of Australia. 61
7033745 1981
423
Indapamide in a single daily dose in the treatment of hypertension. A multicentre trial in private practice. 61
7015538 1981
424
[Treatment of severe resistant arterial hypertension with captopril. 58 patients, including 38 treated for more than 6 months (author's transl)]. 61
7025847 1981
425
Multiclinic comparison of amiloride, hydrochlorothiazide, and hydrochlorothiazide plus amiloride in essential hypertension. Multicenter Diuretic Cooperative Study Group. 61
7011237 1981
426
Labour-onset pre-eclampsia. 61
6942818 1981
427
Effect of diazoxide on the antepartum cardiotocograph in severe pregnancy-associated hypertension. 61
6942817 1981
428
Treatment of severe essential hypertension with labetalol: effect on active and inactive renin. 61
7033992 1981
429
Renin levels and cardiovascular morbidity: a prospective study of the effect of beta-adrenergic blocking drugs. 61
6114813 1981
430
Plasma noradrenaline concentration in hypertensive and normotensive forty-year-old individuals: relationship to plasma renin concentration. 61
6997978 1980
431
Psychological distress and hypertension control. 61
7373028 1980
432
Cardiac performance in hypertension re-evaluated through a combined haemodynamic ultrasonic method. 61
6449209 1980
433
Evaluation of the antihypertensive effect of atenolol in fixed or free combination with chlorthalidone. 61
7010382 1980
434
Ischaemic heart disease in young hypertensive women. 61
7356866 1980
435
Erythrocyte acetylcholinesterase in essential hypertension. 61
7441235 1980
436
Cardiac load and function in hypertension. Ultrasonic and hemodynamic study. 61
495482 1979
437
Sample-size estimation: a sensitivity analysis in the context of a clinical trial for treatment of mild hypertension. 61
375722 1979
438
Labetalol in severe and resistant hypertension. 61
26635156 1979
439
Approach to drug therapy for hypertension. 61
35278 1979
440
Labetalol in severe and resistant hypertension. 61
526395 1979
441
Treatment of mild hypertension. 61
282073 1978
442
Relation of plasma noradrenaline to blood pressure, age, sex and sodium balance in patients with stable essential hypertension and in normotensive subjects. 61
282104 1978
443
[Therapy of hypertension in general practice. Comments on the recommendations of the German Antihypertension League (author's transl)]. 61
306037 1978
444
Managing hypertension: the postgraduate medicine lecture. 61
840801 1977
445
Deoxyribonucleic acid repair synthesis: a new factor for defining high blood pressure. 61
1071712 1976
446
Patient acceptance of guanethidine as therapy for mild to moderate hypertension. A comparison with reserpine. 61
776441 1976
447
Low-tension glaucoma. 61
937430 1976
448
A prospective study of patients with radiological pyelonephritis, papillary necrosis and obstructive atrophy. 61
940921 1976
449
Mild hypertension--a review of 126 cases. 61
819674 1976
450
Borderline hypertension discovered during screening: effect of twelve months' treatment. 61
776582 1976
451
An epidemiologic study of hypertension in Newfoundland. 61
4704904 1973
452
[Treatment of hypertension diastolic blood pressure]. 61
18108273 1948

Variations for Hypertension, Diastolic

ClinVar genetic disease variations for Hypertension, Diastolic:

6 (showing 1, show less) ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 KCNMB1 NM_004137.4(KCNMB1):c.193G>A (p.Glu65Lys)SNV protective 5941 rs11739136 5:169810796-169810796 5:170383792-170383792

Expression for Hypertension, Diastolic

Search GEO for disease gene expression data for Hypertension, Diastolic.

Pathways for Hypertension, Diastolic

Pathways related to Hypertension, Diastolic according to GeneCards Suite gene sharing:

(showing 3, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.06 REN ACE
2 10.64 REN KCNMA1 ACE
3
Show member pathways
10.58 KCNMB1 KCNMA1

GO Terms for Hypertension, Diastolic

Cellular components related to Hypertension, Diastolic according to GeneCards Suite gene sharing:

(showing 2, show less)
# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.43 REN KCNMB1 KCNMA1 KCNIP1 GGT1 ACE
2 voltage-gated potassium channel complex GO:0008076 8.8 KCNMB1 KCNMA1 KCNIP1

Biological processes related to Hypertension, Diastolic according to GeneCards Suite gene sharing:

(showing 6, show less)
# Name GO ID Score Top Affiliating Genes
1 response to calcium ion GO:0051592 9.37 KCNMB1 KCNMA1
2 potassium ion transport GO:0006813 9.33 KCNMB1 KCNMA1 KCNIP1
3 regulation of blood pressure GO:0008217 9.32 REN ACE
4 amyloid-beta metabolic process GO:0050435 9.26 REN ACE
5 potassium ion transmembrane transport GO:0071805 9.13 KCNMB1 KCNMA1 KCNIP1
6 angiotensin maturation GO:0002003 8.62 REN ACE

Molecular functions related to Hypertension, Diastolic according to GeneCards Suite gene sharing:

(showing 5, show less)
# Name GO ID Score Top Affiliating Genes
1 peptidase activity GO:0008233 9.43 REN GGT1 ACE
2 endopeptidase activity GO:0004175 9.32 REN ACE
3 potassium channel activity GO:0005267 9.16 KCNMA1 KCNIP1
4 potassium channel regulator activity GO:0015459 8.96 KCNMB1 KCNIP1
5 calcium-activated potassium channel activity GO:0015269 8.62 KCNMB1 KCNMA1

Sources for Hypertension, Diastolic

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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