MCID: HYP047
MIFTS: 23

Hypertropia

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Hypertropia

MalaCards integrated aliases for Hypertropia:

Name: Hypertropia 12 77 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:9837
ICD9CM 36 378.31
MeSH 45 D013285
NCIt 51 C34716
SNOMED-CT 69 40608009
ICD10 34 H50.2
UMLS 74 C0020575

Summaries for Hypertropia

MalaCards based summary : Hypertropia is related to hypotropia and fourth cranial nerve palsy, familial congenital. An important gene associated with Hypertropia is KIF21A (Kinesin Family Member 21A). The drugs Acetylcholine and Botulinum Toxins have been mentioned in the context of this disorder. Affiliated tissues include eye.

Wikipedia : 77 Hypertropia is a condition of misalignment of the eyes (strabismus), whereby the visual axis of one eye... more...

Related Diseases for Hypertropia

Diseases related to Hypertropia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)
# Related Disease Score Top Affiliating Genes
1 hypotropia 11.3
2 fourth cranial nerve palsy, familial congenital 11.1
3 alternating exotropia 10.4
4 exotropia 10.4
5 strabismus 10.1
6 abducens palsy 10.0
7 retinal detachment 10.0
8 cataract 10.0
9 hemangioma 10.0
10 monocular esotropia 10.0
11 suppression amblyopia 10.0
12 amblyopia 10.0
13 synostosis 10.0
14 intramuscular hemangioma 10.0
15 mechanical strabismus 10.0
16 esotropia 10.0
17 ocular motility disease 9.7 KIF21A NT5C3A

Graphical network of the top 20 diseases related to Hypertropia:



Diseases related to Hypertropia

Symptoms & Phenotypes for Hypertropia

Drugs & Therapeutics for Hypertropia

Drugs for Hypertropia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved, Investigational 51-84-3 187
2 Botulinum Toxins
3 Acetylcholine Release Inhibitors
4 abobotulinumtoxinA
5 Neurotransmitter Agents
6 Cholinergic Agents
7 Botulinum Toxins, Type A

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Prospective Observational Study of Adult Strabismus Completed NCT02510040
2 Routine Care Study Evaluating Ocular Torsion Recruiting NCT02894411

Search NIH Clinical Center for Hypertropia

Genetic Tests for Hypertropia

Anatomical Context for Hypertropia

MalaCards organs/tissues related to Hypertropia:

42
Eye

Publications for Hypertropia

Articles related to Hypertropia:

(show top 50) (show all 65)
# Title Authors Year
1
Surgical Outcome of Single Inferior Oblique Myectomy in Small and Large Hypertropia of Unilateral Superior Oblique Palsy. ( 30371917 )
2019
2
Superior Oblique Palsy: Efficacy of Isolated Inferior Oblique Recession in Cases with Ipsilateral Hypertropia in Abduction. ( 30615559 )
2019
3
Optic Nerve Sheath Tethering in Adduction Occurs in Esotropia and Hypertropia, But Not in Exotropia. ( 30025141 )
2018
4
Inferior Oblique Belly Transposition for Small Angle Hypertropia With Inferior Oblique Overaction: A Pilot Study. ( 28991348 )
2018
5
Treatment of Small Angle Hypertropia With Inferior Oblique Overaction. ( 29378079 )
2018
6
Adult-onset nonparalytic, small-angle hypertropia. ( 30321668 )
2018
7
Trapdoor orbital floor fracture and inferior rectus entrapment with minimal infraduction deficit and hypertropia. ( 30503008 )
2018
8
Comparing Hypertropia in Upgaze and Downgaze Distinguishes Congenital From Acquired Fourth Nerve Palsies. ( 27787462 )
2017
9
Resolution of hypertropia with correction of consecutive horizontal deviation. ( 28499831 )
2017
10
Teaching Video NeuroImages: Alternating skew deviation with abducting hypertropia following superior colliculus infarction. ( 26928363 )
2016
11
Hypertropia in unilateral isolated abducens palsy. ( 24924275 )
2014
12
Inferior oblique anterior transposition for the unilateral hypertropia associated with bilateral inferior rectus muscle aplasia. ( 24767828 )
2014
13
Accuracy of double Maddox rod with induced hypertropia in normal subjects. ( 25313115 )
2014
14
Isolated inferior oblique myectomy for hypertropia. ( 25603661 )
2014
15
Resolution of hypertropia with correction of intermittent exotropia. ( 23934140 )
2013
16
Relationship of hypertropia and excyclotorsion in superior oblique palsy. ( 23372378 )
2013
17
Inferior oblique transposition for large hypertropia after vertical rectus transposition. ( 23618631 )
2013
18
Combined resection and anterior transposition of the inferior oblique muscle for treatment of large primary position hypertropia caused by unilateral superior oblique muscle palsy. ( 23993717 )
2013
19
Hypertropia following Spontaneous Resolution of Brown's Syndrome. ( 22855678 )
2012
20
Adult hypertropia: a guide to diagnostic evaluation based on review of 300 patients. ( 21057518 )
2011
21
Functional imaging of human extraocular muscles in head tilt dependent hypertropia. ( 21282574 )
2011
22
Surgical management of clinically significant hypertropia associated with exotropia. ( 20603056 )
2010
23
Scleral Graft and Muscle Transposition in the Treatment of Scleromalacia and Hypertropia Following Retinal Detachment Surgery. ( 20337346 )
2010
24
Unilateral myelinated nerve fibers associated with hypertropia, strabismus and amblyopia? Reverse straatsma syndrome? ( 19132949 )
2008
25
'Surgical outcomes of intermittent exotropia associated with concomitant hypertropia including simulated superior oblique palsy after horizontal muscles surgery only' by YA Cho and S-H Kim. ( 18670464 )
2008
26
Surgical management for large hypertropia and exotropia after disinsertion of inferior rectus muscle. ( 19065984 )
2008
27
Surgical outcomes of intermittent exotropia associated with concomitant hypertropia including simulated superior oblique palsy after horizontal muscles surgery only. ( 17016462 )
2007
28
Treatment of incomitant hypertropia and diplopia with recession of the inferior rectus and superior rectus muscles of the same eye. ( 17572341 )
2007
29
Incidence and types of childhood hypertropia: a population-based study. ( 16647125 )
2006
30
Hypertropia associated with superolateral translation of the superior rectus muscle pulley in unilateral coronal synostosis. ( 16908815 )
2006
31
A case of intramuscular hemangioma presenting with large-angle hypertropia. ( 17004637 )
2006
32
Unilateral anterior transposition and resection of the inferior oblique muscle for the treatment of hypertropia. ( 15977869 )
2005
33
Inferior rectus pulley hindrance: a mechanism of restrictive hypertropia following lower lid surgery. ( 15314594 )
2004
34
Graded partial tenotomy of vertical rectus muscles for treatment of hypertropia. ( 15747755 )
2004
35
Unilateral anterior transposition of the inferior oblique muscle for correction of hypertropia in primary position. ( 12917609 )
2003
36
Grand rounds #66: a case of a residual left hypertropia after surgery for a paralysis of the inferior division of the 3rd nerve. ( 12067267 )
2002
37
Grand rounds #65: a case of a left hypertropia which decreases markedly in both upgaze and downgaze. ( 11874381 )
2002
38
Two entities in which a dissociative hypertropia may present after surgery. ( 11874375 )
2002
39
Monofixation with eso-, exo-, or hypertropia: is there a difference? ( 21149032 )
2001
40
Anterior transposition of the superior oblique tendon in the treatment of oculomotor nerve palsy and its influence on postoperative hypertropia. ( 10845415 )
2000
41
Grand rounds #52: a case of a residual left exotropia and hypertropia after previous surgery for a third nerve palsy. ( 9852443 )
1998
42
Hypertropia and the posterior blowout fracture. ( 8684811 )
1996
43
Ipsilateral hypertropia after cataract surgery. ( 8637680 )
1996
44
Hypertropia and the posterior blowout fracture: Mechanism and management. ( 8628546 )
1996
45
Unilateral congenital fibrosis syndrome presenting with hypertropia. ( 8154269 )
1993
46
Hypertropia after implantation of a Molteno drainage device. ( 1728155 )
1992
47
Hypertropia following trochlear trauma. ( 1432500 )
1992
48
Hypertropia following insertion of inferiorly sited double-plate Molteno tubes. ( 1286718 )
1992
49
Alternating skew on lateral gaze (bilateral abducting hypertropia). ( 3377440 )
1988
50
Superior oblique strengthening procedures in hypertropia I and II. ( 438930 )
1979

Variations for Hypertropia

Expression for Hypertropia

Search GEO for disease gene expression data for Hypertropia.

Pathways for Hypertropia

GO Terms for Hypertropia

Sources for Hypertropia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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