MCID: HYP080
MIFTS: 50

Hypogonadism

Categories: Endocrine diseases

Aliases & Classifications for Hypogonadism

MalaCards integrated aliases for Hypogonadism:

Name: Hypogonadism 12 74 29 54 43 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:1924
MeSH 43 D007006
NCIt 49 C9227
SNOMED-CT 67 48130008
UMLS 71 C0020619

Summaries for Hypogonadism

Disease Ontology : 12 A gonadal disease that is characterized by diminished functional activity of the gonads.

MalaCards based summary : Hypogonadism is related to hypogonadotropic hypogonadism 7 with or without anosmia and hypogonadotropic hypogonadism 23 without anosmia. An important gene associated with Hypogonadism is GNRH1 (Gonadotropin Releasing Hormone 1), and among its related pathways/superpathways are Signaling by GPCR and Peptide ligand-binding receptors. The drugs Liraglutide and Dihydrotachysterol have been mentioned in the context of this disorder. Affiliated tissues include pituitary, bone and prostate, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 74 Hypogonadism means diminished functional activity of the gonads-the testes or the ovaries-that may... more...

Related Diseases for Hypogonadism

Diseases related to Hypogonadism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 897)
# Related Disease Score Top Affiliating Genes
1 hypogonadotropic hypogonadism 7 with or without anosmia 34.5 SPRY4 PROKR2 GNRHR GNRH1 FGFR1 FGF17
2 hypogonadotropic hypogonadism 23 without anosmia 34.3 PROKR2 NSMF LHB GNRHR GNRH1 ANOS1
3 congenital hypogonadotropic hypogonadism 34.0 GNRHR FGFR1 DUSP6 CHD7 ANOS1
4 hypogonadotropism 33.1 TACR3 TAC3 PROKR2 KISS1R KISS1 GNRHR
5 hypogonadotropic hypogonadism 32.9 TACR3 TAC3 SPRY4 PROKR2 PROK2 NSMF
6 normosmic congenital hypogonadotropic hypogonadism 32.9 TACR3 TAC3 SPRY4 PROKR2 PROK2 NSMF
7 premature ovarian failure 1 32.8 NR0B1 LHCGR KISS1R KISS1 GNRH1 FSHB
8 kallmann syndrome 32.7 TACR3 TAC3 SPRY4 PROKR2 PROK2 NSMF
9 charge syndrome 32.1 TACR3 TAC3 PROKR2 PROK2 NSMF KISS1R
10 amenorrhea 31.3 LHCGR LHB GNRHR GNRH1 FSHB
11 infertility 31.3 LHCGR LHB GNRH1 FSHB
12 hypopituitarism 31.2 PROKR2 PROK2 GNRH1 FSHB
13 precocious puberty 31.0 LHCGR KISS1R KISS1 GNRH1
14 renal hypodysplasia/aplasia 1 30.7 PROKR2 PROK2 GNRH1 FGFR1 ANOS1
15 ovarian hyperstimulation syndrome 30.6 LHCGR GNRH1 FSHB
16 coloboma of macula 30.6 TACR3 PROKR2 PROK2 NSMF KISS1R GNRHR
17 pseudohermaphroditism 30.6 NR0B1 LHCGR LHB
18 cryptorchidism, unilateral or bilateral 30.5 TACR3 TAC3 SPRY4 PROKR2 PROK2 NSMF
19 anovulation 30.5 KISS1 GNRH1 FSHB
20 choanal atresia, posterior 30.3 TACR3 PROKR2 PROK2 NSMF GNRHR CHD7
21 central precocious puberty 30.2 KISS1R KISS1 GNRH1
22 sex development disorder 30.1 LHCGR KISS1 GNRH1
23 pseudovaginal perineoscrotal hypospadias 29.9 LHCGR GNRH1
24 septooptic dysplasia 29.8 PROKR2 PROK2 GNRHR GNRH1 FSHB FGFR1
25 hypogonadotropic hypogonadism 1 with or without anosmia 12.6
26 hypogonadotropic hypogonadism 21 with or without anosmia 12.6
27 hypogonadotropic hypogonadism 10 with or without anosmia 12.6
28 hypogonadotropic hypogonadism 8 with or without anosmia 12.6
29 hypogonadotropic hypogonadism 12 with or without anosmia 12.6
30 hypogonadotropic hypogonadism 20 with or without anosmia 12.6
31 hypogonadotropic hypogonadism 14 with or without anosmia 12.6
32 hypogonadotropic hypogonadism 15 with or without anosmia 12.6
33 hypogonadotropic hypogonadism 11 with or without anosmia 12.6
34 hypogonadotropic hypogonadism 13 with or without anosmia 12.6
35 hypogonadotropic hypogonadism 16 with or without anosmia 12.6
36 cardiomyopathy, dilated, with hypergonadotropic hypogonadism 12.6
37 hypogonadotropic hypogonadism 9 with or without anosmia 12.6
38 hypogonadotropic hypogonadism 4 with or without anosmia 12.6
39 hypogonadotropic hypogonadism 5 with or without anosmia 12.6
40 hypogonadotropic hypogonadism 17 with or without anosmia 12.6
41 hypogonadotropic hypogonadism 19 with or without anosmia 12.6
42 hypogonadotropic hypogonadism 22 with or without anosmia 12.6
43 hypogonadotropic hypogonadism 18 with or without anosmia 12.6
44 hypogonadotropic hypogonadism 3 with or without anosmia 12.6
45 hypogonadotropic hypogonadism 2 with or without anosmia 12.6
46 hypogonadotropic hypogonadism 6 with or without anosmia 12.6
47 leukodystrophy, hypomyelinating, 8, with or without oligodontia and/or hypogonadotropic hypogonadism 12.5
48 hypogonadism, male 12.5
49 leukodystrophy, hypomyelinating, 7, with or without oligodontia and/or hypogonadotropic hypogonadism 12.5
50 hypogonadotropic hypogonadism 24 without anosmia 12.5

Graphical network of the top 20 diseases related to Hypogonadism:



Diseases related to Hypogonadism

Symptoms & Phenotypes for Hypogonadism

GenomeRNAi Phenotypes related to Hypogonadism according to GeneCards Suite gene sharing:

26 (show all 23)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.74 FGFR1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-125 9.74 FGFR1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-126 9.74 FGFR1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-132 9.74 KISS1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-137 9.74 KISS1R
6 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.74 KISS1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.74 FGFR1 KISS1 KISS1R LHB
8 Increased shRNA abundance (Z-score > 2) GR00366-A-180 9.74 KISS1R
9 Increased shRNA abundance (Z-score > 2) GR00366-A-183 9.74 FGFR1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.74 LHB
11 Increased shRNA abundance (Z-score > 2) GR00366-A-205 9.74 KISS1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-26 9.74 FGFR1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-43 9.74 FGFR1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-47 9.74 FGFR1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-49 9.74 LHB
16 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.74 FGFR1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-56 9.74 KISS1R
18 Increased shRNA abundance (Z-score > 2) GR00366-A-57 9.74 KISS1
19 Increased shRNA abundance (Z-score > 2) GR00366-A-60 9.74 KISS1R
20 Increased shRNA abundance (Z-score > 2) GR00366-A-73 9.74 FGFR1
21 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.74 KISS1R
22 Increased shRNA abundance (Z-score > 2) GR00366-A-83 9.74 FGFR1
23 Increased shRNA abundance (Z-score > 2) GR00366-A-97 9.74 LHB

MGI Mouse Phenotypes related to Hypogonadism:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 10.17 CHD7 FGFR1 FSHB GNRH1 GNRHR KISS1
2 growth/size/body region MP:0005378 10.03 CHD7 DUSP6 FGFR1 GNRH1 GNRHR KISS1
3 homeostasis/metabolism MP:0005376 10.03 CHD7 DUSP6 FGFR1 FSHB GNRH1 GNRHR
4 digestive/alimentary MP:0005381 10.02 CHD7 FGFR1 GNRH1 GNRHR KISS1 KISS1R
5 nervous system MP:0003631 9.7 CHD7 FGF17 FGFR1 GNRH1 KISS1 KISS1R
6 reproductive system MP:0005389 9.5 CHD7 DCAF17 FGFR1 FSHB GNRH1 GNRHR

Drugs & Therapeutics for Hypogonadism

Drugs for Hypogonadism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 191)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Liraglutide Approved Phase 4 204656-20-2 44147092
2
Dihydrotachysterol Approved Phase 4 67-96-9 5281010 5311071
3
Metformin Approved Phase 4 657-24-9 14219 4091
4
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
5 Nutmeg Approved Phase 4
6
Menotropins Approved Phase 4 9002-68-0, 61489-71-2 5360545
7
N,N-dimethylarginine Experimental Phase 4 30315-93-6 123831
8
Deslorelin Investigational, Vet_approved Phase 4 57773-65-6
9 Hypoglycemic Agents Phase 4
10 Incretins Phase 4
11 Luteolytic Agents Phase 4
12 Triptorelin Pamoate Phase 4
13 Fenugreek seed meal Phase 4
14 Fenugreek Phase 4
15 Tranquilizing Agents Phase 4
16 Dopamine D2 Receptor Antagonists Phase 4
17 Psychotropic Drugs Phase 4
18 Serotonin 5-HT2 Receptor Antagonists Phase 4
19 Serotonin 5-HT1 Receptor Agonists Phase 4
20 Dopamine Antagonists Phase 4
21 Serotonin Agents Phase 4
22 Antipsychotic Agents Phase 4
23 Antidepressive Agents Phase 4
24 Dopamine agonists Phase 4
25 Serotonin Receptor Agonists Phase 4
26 Serotonin Antagonists Phase 4
27 Hypolipidemic Agents Phase 4
28 Rosuvastatin Calcium Phase 4 147098-20-2
29 Anticholesteremic Agents Phase 4
30 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
31 Antimetabolites Phase 4
32 Lipid Regulating Agents Phase 4
33 Mace Phase 4
34 Follicle Stimulating Hormone Phase 4
35 Pharmaceutical Solutions Phase 4
36 Phosphodiesterase 5 Inhibitors Phase 4
37 Phosphodiesterase Inhibitors Phase 4
38 Vardenafil Dihydrochloride Phase 4
39 Vasodilator Agents Phase 4
40
Serotonin Investigational, Nutraceutical Phase 4 50-67-9 5202
41
Dopamine Approved Phase 3 51-61-6, 62-31-7 681
42
Bromocriptine Approved, Investigational Phase 3 25614-03-3 31101
43
Mirtazapine Approved Phase 3 85650-52-8, 61337-67-5 4205
44
Amphetamine Approved, Illicit, Investigational Phase 3 300-62-9 5826 3007
45
Histamine Approved, Investigational Phase 3 51-45-6 774
46
Alendronate Approved Phase 3 121268-17-5, 66376-36-1 2088
47
Letrozole Approved, Investigational Phase 3 112809-51-5 3902
48
Tadalafil Approved, Investigational Phase 3 171596-29-5 110635
49
tannic acid Approved Phase 3 1401-55-4
50
Benzocaine Approved, Investigational Phase 3 1994-09-7, 94-09-7 2337

Interventional clinical trials:

(show top 50) (show all 395)
# Name Status NCT ID Phase Drugs
1 Human Menopausal Gonadotropin Combining With Human Chorionic Gonadotropin is Superior to Human Chorionic Gonadotropin in Therapeutic Efficacy in Adolescent Boys With Congenital Hypogonadotropic Hypogonadism Unknown status NCT02880280 Phase 4 Human Menopausal Gonadotropin;Human Chorionic Gonadotropin
2 The Effect of Testim and Training in a Population Based, Randomized, Placebo-controlled, Double-blinded Study of Hypogonadal Men Unknown status NCT00700024 Phase 4 Testim;placebo
3 Effect of Androgel on Inflammatory Mediators and Oxidative Stress in Type 2 Diabetic Males With Hypogonadism Unknown status NCT00350701 Phase 4 androgel;androgel 10g;placebo
4 Aromatase Inhibitors and Weight Loss in Severely Obese Hypogonadal Male Veterans (Pilot) Unknown status NCT02959853 Phase 4 Anastrazole
5 Study on the Efficacy and Safety of Pulsatile Gonadotropin Releasing Hormone Pump Treatment in Patients With Idiopathic Hypogonadotropic Hypogonadism Unknown status NCT02310074 Phase 4 Pulsatile Gonadotropin Releasing Hormone;Human chorionic gonadotropin;Urinary Follicle-Stimulating Hormone
6 Comparison of Assisted Reproductive Technology (ART) Outcomes Between Two Protocols of Induction of Ovulation by Using Recombinant Luteinizing Hormone (rLH) and Recombinant Follicle Stimulating Hormone (rFSH) in Patients With Hypogonadotropic Hypogonadism Unknown status NCT02140515 Phase 4 Lutropin alfa;Follitropin alfa and Lutropin alfa
7 Phase IV Study to Investigate the Effect of Testosterone Treatment on Paraoxonase Level in Male Patients With Hypogonadotrophic Hypogonadism Completed NCT01107067 Phase 4 Sustanon
8 Phase 4 Study of About the Effect of Testosterone Treatment on the Components of Metabolic Syndrome Completed NCT01160341 Phase 4 Testosteron
9 Effects of Three Different Medications on Metabolic Parameters and Testicular Volume in Patients With Hypogonadotropic Hypogonadism-Last Three Years Experience Completed NCT01601327 Phase 4 Testosterone enanthate (Sustanon 250 mg);Human chorionic gonadotropin (hCG) (Pregnyl 5000 IU);Testosteron gel (Testojel 50 mg)
10 Effects of Liraglutide and Testosterone Replacement Therapy on Features of Hypogonadism and Weight Loss in Obese Men With Persistent Features of Hypogonadism. Completed NCT03619330 Phase 4 liraglutide;Testosterone
11 Phase 4 Study of Effect of Testosteron Treatment on the Visceral Adiposity Index and Triglyceride/High-density Lipoprotein Cholesterol Ratio in the Congenital Hypogonadotropic Hypogonadism Completed NCT02111434 Phase 4 Testosterone
12 Phase 4 Study That Evaluates the Presence of Endothelial Dysfunction, Inflammation and Insulin Resistance in Male Subjects With Hypogonadotrophic Hypogonadism and Effects of Two Different Testosterone Replacement Regiments on These Parameters. Completed NCT02171390 Phase 4 Testosterone 250mg injection;Testosteron 50 mg transdermal gel
13 Phase 4 Study That Evaluates the Effects of Two Different Testosterone Replacement Regiments on Endothelial Dysfunction, Inflammation and Insulin Resistance in Male Subjects With Hypogonadotrophic Hypogonadism. Completed NCT01533129 Phase 4 Testogel 50 mg transdermal gel;Testosterone 250mg injection
14 The Effect of Testosterone Topical Solution (LY900011) in Hypogonadal Men With Suboptimal Response to a Topical Testosterone Gel Completed NCT01893281 Phase 4 Topical Testosterone Solution
15 Phase 4 Study That Compares the High Density Lipoprotein Cholesterol (HDL) Cholesterol Subgroups of the Patients With Congenital Hypogonadotrophic Hypogonadism With That of the Healthy Control Subjects, and Investigates the Effect of Testosterone Treatment on HDL Subgroups. Completed NCT01454011 Phase 4 Testosteron 250mg injection;Testosterone 50mg transdermal application
16 Efficacy and Safety of Human Chorionic Gonadotropin (HCG) and Follicle Stimulating Hormone (FSH) in the Treatment of Hypogonadotropic Hypogonadism Completed NCT01403532 Phase 4 Traditional intervention for HH using HCG and FSH;Sequential intervention for HH using HCG and FSH;Sequential intervention for HH using HCG and FSH plus zinc
17 Study on Effects of Testosterone Replacement Therapy in Hypogonadal Type 2 Completed NCT03792321 Phase 4 Testosterone Undecanoate;Placebo
18 A Randomised, Double Blind, Placebo Controlled, Parallel Pilot Study to Test the Effect of Testosterone Treatment on Peripheral Vascular Disease in Hypogonadal Men With Type 2 Diabetes Mellitus Completed NCT00504712 Phase 4 Testosterone;saline
19 MRI Substudy; Metabolic Changes Due to Iatrogenic Hypogonadism in Patients With Prostate Cancer: Orchiectomy vs. Triptorelin Completed NCT02102646 Phase 4 Triptorelin
20 Phase 4 Study of Effect of Testosteron Replacement Treatment on the Fibroblast Growth Factor-23, Asymmetric Dimethylarginine and Vitamin D Levels in the Congenital Hypogonadotropic Hypogonadism Completed NCT02111473 Phase 4 Testosterone
21 A Randomised, Double Blind, Placebo-controlled Parallel Study to Test the Effect of Testosterone Treatment on Peripheral Vascular Disease in Hypogonadal Men With Type 2 Diabetes Mellitus Completed NCT00355537 Phase 4 Testosterone;0.9% saline
22 Testosterone Replacement and Dutasteride Effectiveness (TRADE) Completed NCT00194675 Phase 4 Dutasteride;Testosterone gel;Placebo dutasteride
23 Effect of Testosterone Replacement on Insulin Resistance in Hypogonadal, Non-obese Men With Metabolic Syndrome Completed NCT00487734 Phase 4 Placebo for testosterone gel
24 Phase IV Study of The Therapy of Long-acting Testosterone Undecanoate,1000mg in 4 ml Oily Solution for i.m.Injection(Nebido) as Mono or in Combination With PDE-5 Inhibitors in Hypogonadal Patients With Erectile Dysfunction Completed NCT00421460 Phase 4 Testosterone Undecanoate,1000mg
25 A Randomized, Double-blind, Placebo Controlled Trial to Evaluate the Effects of Vitamin D Supplementation on Androgen Levels in Hypogonadal Men Completed NCT01748370 Phase 4 Vitamin D supplementation in hypogonadal men;Vitamin D supplementation in eugonadal men;Placebo hypogonadal;Placebo eugonadal
26 Testosterone Replacement in Metabolic Syndrome and Inflammation of Fat Tissue Completed NCT01123278 Phase 4 Testosterone;Placebo
27 A Randomised Double Blind Placebo Controlled, Parallel Pilot Study to Test the Effect of Testosterone Replacement on Glycaemic Control and Arterial Wall Properties of Hypogonadal Men With Type 2 Diabetes Treated With Insulin Completed NCT00349362 Phase 4 Testosterone;0.9% saline
28 Effect of Hypogonadotrophic Hypogonadism and Treatment With Testosterone on Insulin Sensitivity, Inflammation, Body Composition and Sexual Function in Obese and Type 2 Diabetic Men Completed NCT01127659 Phase 4 testosterone;placebo
29 Aripiprazole Treatment for Antipsychotic Induced Hyperprolactinaemia in Patients With Severe Mental Illness and Learning Disabilities Completed NCT01085383 Phase 4 Aripiprazole
30 Testosterone Therapy of Men With Type 2 Diabetes Mellitus (T2DM) - a Randomised, Doubleblinded and Placebocontrolled Trial of Men With Subnormal Testosterone Levels and T2DM. Completed NCT01560546 Phase 4 Testosterone;Placebo
31 A 150-Day, Prospective, Phase 4, Open-Label Study, Evaluating Patient Satisfaction and Symptom Improvement When Treating Male Hypogonadism With Testosterone Nasal Gel (Natesto™) Completed NCT02937740 Phase 4 NATESTO Testosterone Nasal Gel
32 Dutasteride in Men Receiving Testosterone Therapy: Impact on Serum PSA, Testosterone, DHT Levels and Prostate Volume: "Implications for Prostate Safety" Completed NCT00752869 Phase 4 dutasteride;placebo
33 Effects of Testosterone on Myocardial Repolarization in Patients With Hypogonadism With/Without Chronic Heat Failure (NYHA Class I-II) Completed NCT03126656 Phase 4 Testosterone Undecanoate
34 Effectiveness of Testosterone Replacement Therapy (TRT) on Prostatic Gland in Hypogonadal Patients Affected by Benign Prostatic Hyperplasia (BPH) and Metabolic Syndrome (MetS). Florence-PROTEST Completed NCT02366975 Phase 4 Testosterone gel 2%
35 Statin Therapy is Associated With Low Testosterone and Sexual Function in Men With Type 2 Diabetes Completed NCT02612714 Phase 4 Rosuvastatin
36 To Define the Individual Need of Exogenous LH During Ovarian Stimulation for Severe LH Suppressed Patients After Administration of a GnRH Antagonist Completed NCT01936077 Phase 4 Recombinant LH (Luveris)
37 Subcutaneous Testosterone Therapy in Men Compared to Intramuscular Testosterone Therapy in Men Completed NCT03091348 Phase 4 Testosterone
38 Estrogen Dosing in Turner Syndrome:Pharmacology & Metabolism Completed NCT00837616 Phase 4 17 B estradiol orally;17 B estradiol
39 Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy Completed NCT01201863 Phase 4 Androgel (Testosterone Gel);Androgel Placebo
40 Efficacy and Safety of a Mixed Extract of Fenugreek Seed and Lespedeza Cuneata in the Treatment of Testosterone Deficiency Syndrome: A Randomized, Double-blind, Placebo-Controlled Clinical Trial Completed NCT03057899 Phase 4 TFG capsules (200 mg /capsule);Placebo oral capsule
41 Final Oocyte Maturation Via Administration of GnRH Agonists Followed By Luteal Support With hCG Completed NCT01638026 Phase 4 TRIPTORELIN ACETATE, hCG
42 Combined Influence of Puberty and Obesity on Insulin Resistance in Adolescents Completed NCT01775813 Phase 4 Metformin
43 Effects of Testosterone Replacement on Atherosclerosis Progression in Older Men With Low Testosterone Levels Completed NCT00287586 Phase 4 Testosterone Gel (Androgel);Placebo
44 FSH/LH Ratio as a Predictor of IVF Outcome in Young and Older Women Completed NCT02674178 Phase 4
45 An Integrated Approach With Vardenafil Orodispersible and Cognitive-behavioral Sex Therapy for the Treatment of Erectile Dysfunction (STEDOV) Completed NCT02450188 Phase 4 Vardenafil
46 Testosterone Replacement Therapy for Assessment of Long-term Vascular Events and Efficacy ResponSE in Hypogonadal Men (TRAVERSE) Study Recruiting NCT03518034 Phase 4 Testosterone;Placebo
47 The Effect of Testosterone Replacement in Patients With Hypogonadotrophic Hypogonadism Due to Opioid Treatment for Non-malignant Disease Recruiting NCT02433730 Phase 4 Testosterone;placebo
48 Natesto Effects on Testosterone, Luteinizing Hormone, Follicle Stimulating Hormone and Semen Parameters Recruiting NCT03203681 Phase 4 NATESTO® (4.5% nasal testosterone) Nasal Gel
49 Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism Recruiting NCT03490513 Phase 4 anastrozole (1 mg/day);Placebo
50 Testosterone Therapy and Bone Quality in Men With Diabetes and Hypogonadism Recruiting NCT03887936 Phase 4 Testosterone gel 1.62%;Placebo

Search NIH Clinical Center for Hypogonadism

Inferred drug relations via UMLS 71 / NDF-RT 50 :


2-Bromoergocryptine Mesylate
Black Cohosh Extract
Bromocriptine
Chlorotrianisene
Estradiol
Estradiol acetate
estradiol cypionate
ESTRADIOL PWDR
estradiol valerate
Estrogens
Estrogens, Conjugated (USP)
Estrogens, Esterified (USP)
Estrone
estropipate
Ethinyl Estradiol
Ethynodiol Diacetate
Fluoxymesterone
Methyltestosterone
METHYLTESTOSTERONE PWDR
Norethindrone
norethindrone acetate
polyestradiol
polyestradiol phosphate
Sodium estrone sulfate
synthetic conjugated estrogens, A
synthetic conjugated estrogens, B
Testosterone
testosterone cypionate
testosterone enanthate
Testosterone Propionate
TESTOSTERONE PROPIONATE PWDR
TESTOSTERONE PWDR
testosterone undecanoate

Cochrane evidence based reviews: hypogonadism

Genetic Tests for Hypogonadism

Genetic tests related to Hypogonadism:

# Genetic test Affiliating Genes
1 Hypogonadism 29

Anatomical Context for Hypogonadism

MalaCards organs/tissues related to Hypogonadism:

40
Pituitary, Bone, Prostate, Testes, Liver, Brain, Thyroid

Publications for Hypogonadism

Articles related to Hypogonadism:

(showing 10214, show less)
# Title Authors PMID Year
1
Novel insights in FGFR1 regulation: lessons from Kallmann syndrome. 54 61
20117945 2010
2
Emotional disorders in testicular cancer survivors in relation to hypogonadism, androgen receptor polymorphism and treatment modality. 54 61
19656574 2010
3
[Case of progressive prostatic carcinoma in a patient with acquired hypogonadism]. 54 61
20448451 2010
4
A new FSHbeta mutation in a 29-year-old woman with primary amenorrhea and isolated FSH deficiency: functional characterization and ovarian response to human recombinant FSH. 54 61
19966036 2010
5
Management of erectile dysfunction. 54 61
20112889 2010
6
Recombinant follitropin alfa/lutropin alfa in fertility treatment. 54 61
20161981 2010
7
The relationship of testosterone to prostate-specific antigen in men with sexual dysfunction. 54 61
19912506 2010
8
Narrative review: the role of leptin in human physiology: emerging clinical applications. 54 61
20083828 2010
9
Hypogonadism, ED, metabolic syndrome and obesity: a pathological link supporting cardiovascular diseases. 54 61
19226407 2009
10
Relationship between insulin and hypogonadism in men with metabolic syndrome. 54 61
20126854 2009
11
Prostate cancer and acromegaly. 54 61
20126848 2009
12
Adiponectin and testosterone in patients with symptoms of late-onset hypogonadism: is there a link? 54 61
19719531 2009
13
Effects of rhIGF-1 administration on surrogate markers of bone turnover in adolescents with anorexia nervosa. 54 61
19523548 2009
14
Preservation of GHRH and GH-releasing peptide-2 efficacy in young men with experimentally induced hypogonadism. 54 61
19458139 2009
15
Dimeric PROP1 binding to diverse palindromic TAAT sequences promotes its transcriptional activity. 54 61
19524124 2009
16
The emerging link between hypogonadism and metabolic syndrome. 54 61
18772486 2009
17
Bone mineral density and disorders of mineral metabolism in chronic liver disease. 54 61
19630107 2009
18
Peptide YY in adolescent athletes with amenorrhea, eumenorrheic athletes and non-athletic controls. 54 61
19344792 2009
19
Prostate-specific antigen changes and prostate cancer in hypogonadal men treated with testosterone replacement therapy. 54 61
19154450 2009
20
Androgen receptor roles in spermatogenesis and fertility: lessons from testicular cell-specific androgen receptor knockout mice. 54 61
19176467 2009
21
Leptin: a pivotal regulator of human energy homeostasis. 54 61
19211814 2009
22
Gonadal function in male patients after treatment for malignant lymphomas, with emphasis on chemotherapy. 54 61
19156143 2009
23
Non-functioning pituitary adenomas: clinical feature, laboratorial and imaging assessment, therapeutic management and outcome. 54 61
19347183 2009
24
Has prolactin a role in the hypogonadal status of HIV-infected patients? 54 61
19171915 2009
25
Inactivating mutations of luteinizing hormone beta-subunit or luteinizing hormone receptor cause oligo-amenorrhea and infertility in women. 54 61
19129711 2009
26
FSHbeta gene mutation in a female with delayed puberty and hypogonadism: response to recombinant human FSH. 54 61
20067895 2009
27
Changes in insulin sensitivity during leptin replacement therapy in leptin-deficient patients. 54 61
18854428 2008
28
Laboratory diagnosis of late-onset male hypogonadism andropause. 54 61
19197450 2008
29
Relationship of prostate-specific antigen to age and testosterone in men with type 2 diabetes mellitus. 54 61
19095599 2008
30
[Long-term steroid therapy in children: is adjunct therapy relevant in nephrotic syndrome?]. 54 61
18951767 2008
31
Left ventricular dysfunction in Klinefelter syndrome is associated to insulin resistance, abdominal adiposity and hypogonadism. 54 61
18248650 2008
32
Testosterone and erectile dysfunction. 54 61
18641415 2008
33
Endocrine and metabolic disorders in young adult survivors of childhood acute lymphoblastic leukaemia (ALL) or non-Hodgkin lymphoma (NHL). 54 61
18429947 2008
34
Acylated ghrelin and leptin in adolescent athletes with amenorrhea, eumenorrheic athletes and controls: a cross-sectional study. 54 61
18331605 2008
35
[Testosterone replacement in hypogonadotropic hypogonadal young male improves insulin sensitivity]. 54 61
19080648 2008
36
Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor. 54 61
18449947 2008
37
Kisspeptin and GPR54: discovery of a novel pathway in reproduction. 54 61
18601695 2008
38
Bone density in the adolescent athlete. 54 61
18409004 2008
39
The ratio of serum testosterone-to-prostate specific antigen predicts prostate cancer in hypogonadal men. 54 61
18343420 2008
40
Prevalence of metabolic syndrome in long-term survivors of hematopoietic stem cell transplantation. 54 61
18195686 2008
41
Prevalence of androgen deficiency in men with erectile dysfunction. 54 61
18313109 2008
42
[Phenotype of patients with gynecomastia]. 54 61
18465688 2008
43
The role of cyclase activating (CAP) and cyclase inhibiting (CIP) parathormone fractions in the assessment of bone metabolism disturbances in women with hyperprolactinemia of various origin. 54 61
18283239 2008
44
Seminiferous tubule function in delayed-onset X-linked adrenal hypoplasia congenita associated with incomplete hypogonadotrophic hypogonadism. 54 61
17803711 2008
45
Secondary hypothyroidism in hereditary hemochromatosis: recovery after iron depletion. 54 61
18205549 2008
46
Cholestasis and metabolic bone disease - a clinical review. 54 61
18998071 2008
47
Kisspeptins: a multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system. 54 61
19554077 2008
48
Metabolic syndrome and reproduction: I. testicular function. 54 61
18224542 2008
49
The complex genetics of Kallmann syndrome: KAL1, FGFR1, FGF8, PROKR2, PROK2, et al. 54 61
18987492 2008
50
Androgen deficiency as a predictor of metabolic syndrome in aging men: an opportunity for intervention? 54 61
18447401 2008
51
[Pathogenetically complicated case of osteoporosis in a young man]. 54 61
19097362 2008
52
Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism. 54 61
17726076 2007
53
Bicycle riding, perineal trauma, and erectile dysfunction: data and solutions. 54 61
18042330 2007
54
Testosterone deficiency and the metabolic syndrome. 54 61
17558968 2007
55
Skeletal effects of long-term estrogen and testosterone replacement treatment in a man with congenital aromatase deficiency: evidences of a priming effect of estrogen for sex steroids action on bone. 54 61
17400043 2007
56
Therapeutic uses of aromatase inhibitors in men. 54 61
17940445 2007
57
Martsolf syndrome in Japanese siblings. 54 61
17394201 2007
58
Effects of testosterone on erectile function: implications for the therapy of erectile dysfunction. 54 61
17309554 2007
59
[Insulin-like growth factor I (IGF-I) and liver cirrhosis]. 54 61
17516829 2007
60
Growth hormone reserve in adult beta thalassemia patients. 54 61
17709895 2007
61
Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor. 54 61
17236139 2007
62
Testosterone replacement for hypogonadism after treatment of early prostate cancer with brachytherapy. 54 61
17183557 2007
63
Hypoandrogen-metabolic syndrome: a potentially common and underdiagnosed condition in men. 54 61
17263722 2007
64
Clinical assessment and molecular analysis of GnRHR and KAL1 genes in males with idiopathic hypogonadotrophic hypogonadism. 54 61
17223984 2007
65
Role of endogenous androgen against insulin resistance and athero- sclerosis in men with type 2 diabetes. 54 61
18220653 2007
66
Autosomal-recessive syndrome with alopecia, hypogonadism, progressive extra-pyramidal disorder, white matter disease, sensory neural deafness, diabetes mellitus, and low IGF1. 54 61
17167799 2007
67
Clinical effects of treatment for hypogonadism in male adolescents with Prader-Labhart-Willi syndrome. 54 61
17374959 2007
68
Hypogonadism and reduced bone mineral density in heterozygous H63D mutation in the HFE gene: an unusual presentation of hereditary hemochromatosis. 54 61
16988327 2007
69
Use of cognitive behavior therapy for functional hypothalamic amenorrhea. 54 61
17308138 2006
70
PROP1 gene analysis in Portuguese patients with combined pituitary hormone deficiency. 54 61
16984240 2006
71
Treatment-related osteoporosis in men with prostate cancer. 54 61
17062721 2006
72
Hormonal control of inhibin B in men. 54 61
17033259 2006
73
The evolving role of testosterone in the treatment of erectile dysfunction. 54 61
16939550 2006
74
The impact of genotype on endocrine complications in thalassaemia major. 54 61
16800840 2006
75
Prostate-specific antigen testing in hypogonadism: implications for the safety of testosterone-replacement therapy. 54 61
16831134 2006
76
[Hypogonadism may cause insulin resistance in young males]. 54 61
16894938 2006
77
Hypogonadism in male patients with cancer. 54 61
16688773 2006
78
[Gene as a cause of adrenal hypoplasia, hypogonadism and short height novel mutation of DAX-1 gene (pGly168fsX17)]. 54 61
16792969 2006
79
Prostatic cancer, hypogonadism, and insulin resistance: A case report. 54 61
16644663 2006
80
Characteristic features of 20 patients with Sheehan's syndrome. 54 61
16785150 2006
81
Hypothalamic and gonadal components of hypogonadism in boys with Prader-Labhart- Willi syndrome. 54 61
16352691 2006
82
Hyperglycemia and insulin resistance in men with prostate carcinoma who receive androgen-deprivation therapy. 54 61
16388523 2006
83
A rational approach to androgen therapy for hypogonadal men with prostate cancer. 54 61
16208401 2006
84
Therapy Insight: osteoporosis during hormone therapy for prostate cancer. 54 61
16474548 2005
85
[The application of gonadotropin in treatment of male central hypogonadism]. 54 61
16316564 2005
86
Testosterone therapy in erectile dysfunction and hypogonadism. 54 61
16422803 2005
87
[GnRH resistance and the GPR54 gene]. 54 61
16302709 2005
88
Regulation of expression of mammalian gonadotrophin-releasing hormone receptor genes. 54 61
16159375 2005
89
Hyperprolactinaemia in 271 women: up to three decades of clinical follow-up. 54 61
16181238 2005
90
Ovulation induction: a mini review. 54 61
16006478 2005
91
Effect of gender and gonadal status on the long-term response to somatostatin analogue treatment in acromegaly. 54 61
16117824 2005
92
Hypogonadism and metabolic syndrome: implications for testosterone therapy. 54 61
16093964 2005
93
Oxytocin mediates the estrogen-dependent contractile activity of endothelin-1 in human and rabbit epididymis. 54 61
15860558 2005
94
Effect of gonadotropin-releasing-hormone-induced hypogonadism on insulin action as assessed by euglycemic clamp studies in men. 54 61
16009176 2005
95
Sex steroids and sexual desire in a man with a novel mutation of aromatase gene and hypogonadism. 54 61
15721053 2005
96
Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men. 54 61
15713702 2005
97
Hypogonadism in hereditary hemochromatosis. 54 61
15657376 2005
98
A novel mouse model of hypogonadotrophic hypogonadism: N-ethyl-N-nitrosourea-induced gonadotropin-releasing hormone receptor gene mutation. 54 61
15625238 2005
99
Prostatic specific antigen in patients with hypogonadism: effect of testosterone replacement. 54 61
16422891 2005
100
Effect of aromatase inhibition on lipids and inflammatory markers of cardiovascular disease in elderly men with low testosterone levels. 54 61
15670201 2005
101
Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. 54 61
15665093 2005
102
Antipsychotic drugs: a new risk factor for osteoporosis in young women with schizophrenia? 54 61
15643097 2005
103
Endocrine alterations in critically ill patients with stroke during the early recovery period. 54 61
16377833 2005
104
The effect of testosterone supplement on insulin sensitivity, glucose effectiveness, and acute insulin response after glucose load in male type 2 diabetics. 54 61
16353672 2005
105
Human chorionic gonadotropin therapy in adolescent boys with constitutional delayed puberty vs those with beta-thalassemia major. 54 61
15562375 2005
106
Dominant transmission of prepubertal gynecomastia due to serum estrone excess: hormonal, biochemical, and genetic analysis in a large kindred. 54 61
15483104 2005
107
Kallmann syndrome: 14 novel mutations in KAL1 and FGFR1 (KAL2). 54 61
15605412 2005
108
Acromegaly: effects on bone metabolism and mass. 54 61
16550720 2005
109
Prevalence of osteopenia in men with prolactinoma. 54 61
15816365 2005
110
Selective estrogen receptor modulators to prevent treatment-related osteoporosis. 54 61
16985877 2005
111
High incidence of neuroendocrine dysfunction in long-term survivors of aneurysmal subarachnoid hemorrhage. 54 61
15499033 2004
112
Frequent occurrence of hypogonadotropic hypogonadism in type 2 diabetes. 54 61
15531498 2004
113
A novel polymerase gamma mutation in a family with ophthalmoplegia, neuropathy, and Parkinsonism. 54 61
15534189 2004
114
[Hormone therapy in the aging male. Estrogen, DHEA, melatonin, somatotropin]. 54 61
15309306 2004
115
Impaired insulin secretion in the Turner metabolic syndrome. 54 61
15240640 2004
116
Endocrine aspects of sexual dysfunction in men. 54 61
16422986 2004
117
Occurrence of pituitary dysfunction following traumatic brain injury. 54 61
15253797 2004
118
The formation of an intrachain disulfide bond in the leptin protein is necessary for efficient leptin secretion. 54 61
15358050 2004
119
[Three patients with gynaecomastia]. 54 61
15141644 2004
120
Elevated leptin fragments in renal failure correlate with BMI and haematopoiesis and are normalized by haemodialysis. 54 61
15049957 2004
121
Effect of gonadotropin-releasing hormone hypogonadism on insulin action as assessed by hyperglycemic clamp studies in men. 54 61
15066469 2004
122
Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults. 54 61
15070752 2004
123
Misrouted cell surface GnRH receptors as a disease aetiology for congenital isolated hypogonadotrophic hypogonadism. 54 61
15073146 2004
124
Effects of aromatase inhibition in elderly men with low or borderline-low serum testosterone levels. 54 61
15001605 2004
125
Clinical-biochemical correlations in acromegaly at diagnosis and the real prevalence of biochemically discordant disease. 54 61
15542931 2004
126
Pulsatile gonadotrophin releasing hormone for ovulation induction in subfertility associated with polycystic ovary syndrome. 54 61
14973957 2004
127
Antipsychotic-induced hyperprolactinaemia: mechanisms, clinical features and management. 54 61
15456328 2004
128
Clinical and molecular analysis of human reproductive disorders in Brazilian patients. 54 61
14689055 2004
129
Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency. 54 61
14617756 2003
130
Clinical and molecular genetics of the human GnRH receptor. 54 61
14714589 2003
131
Endocrine effects of nasal continuous positive airway pressure in male patients with obstructive sleep apnoea. 54 61
14535966 2003
132
Hypothyroidism associated with anti-human chorionic gonadotropin antibodies secondarily produced by gonadotropin therapy in a case of idiopathic hypothalamic hypogonadism. 54 61
15008254 2003
133
Risk factors for male osteoporosis. 54 61
14670549 2003
134
Leptin concentrations in semen are correlated with serum leptin and elevated in hypergonadotrophic hypogonadism. 54 61
12950408 2003
135
Growth retardation, developmental delay, distinctive face, multiple endocrine abnormalities, and adenylyl cyclase dysfunction: a new syndrome? 54 61
12838561 2003
136
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome: time to review diagnostic criteria? 54 61
12843157 2003
137
Molecular pathogenesis of lipoid adrenal hyperplasia and adrenal hypoplasia congenita. 54 61
12943739 2003
138
Steroids in adult men with type 1 diabetes: a tendency to hypogonadism. 54 61
12766115 2003
139
Changes in serum leptin levels during GnRH agonist therapy. 54 61
12940465 2003
140
Mono-ovulatory cycles: a key goal in profertility programmes. 54 61
12859047 2003
141
Prostate cancer in patients with Hansen's disease. 54 61
12622716 2003
142
A novel loss of function mutation in exon 10 of the FSH receptor gene causing hypergonadotrophic hypogonadism: clinical and molecular characteristics. 54 61
12571157 2003
143
Analysis of the Cys82Arg mutation in follicle-stimulating hormone beta (FSHbeta) using a novel FSH expression vector. 54 61
12568849 2003
144
Pituitary tumor endocrinopathies and their endocrine evaluation. 54 61
12690978 2003
145
The pleiotropic expression of the myotonic dystrophy protein kinase gene illustrates the complex relationships between genetic, biological and clinical covariates of male aging. 54 61
12630069 2002
146
The effects of gender and gonadal steroids on the neuroendocrine and temperature response to m-chlorophenylpiperazine in leuprolide-induced hypogonadism in women and men. 54 61
12431854 2002
147
Maintenance of spermatogenesis in hypogonadotropic hypogonadal men with human chorionic gonadotropin alone. 54 61
12444893 2002
148
Prostate-specific antigen changes in hypogonadal men treated with testosterone replacement. 54 61
12399540 2002
149
The novel use of very high doses of cabergoline and a combination of testosterone and an aromatase inhibitor in the treatment of a giant prolactinoma. 54 61
12364416 2002
150
Progressive onset of adrenal insufficiency and hypogonadism of pituitary origin caused by a complex genetic rearrangement within DAX-1. 54 61
12213854 2002
151
Hypoparathyroidism in transfusion-dependent patients with beta-thalassemia. 54 61
11972098 2002
152
GnRH neuronal development: insights into hypogonadotrophic hypogonadism. 54 61
11893524 2002
153
Endocrine and metabolic abnormalities involved in obesity associated with typical antipsychotic drug administration. 54 61
11778142 2001
154
Depression: a major, unrecognized risk factor for osteoporosis? 54 61
11397644 2001
155
Neurophysiological regulation and target-tissue impact of the pulsatile mode of growth hormone secretion in the human. 54 61
11527085 2001
156
Pituitary prolactin-secreting macroadenoma combined with bilateral breast cancer in a 45-year-old male. 54 61
11434671 2001
157
Recombinant human growth hormone and recombinant human insulin-like growth factor I diminish the catabolic effects of hypogonadism in man: metabolic and molecular effects. 54 61
11344229 2001
158
A novel homozygous mutation in the second transmembrane domain of the gonadotrophin releasing hormone receptor gene. 54 61
11318785 2001
159
The 'hook effect' on serum prolactin estimation in a patient with macroprolactinoma. 54 61
11303248 2001
160
Hypogonadism in patients with acromegaly: data from the multi-centre acromegaly registry pilot study. 54 61
11207632 2001
161
Central control of bone formation. 54 61
11368306 2001
162
Use of the dopamine agonists bromocriptine and cabergoline in the management of risperidone-induced hyperprolactinemia in patients with psychotic disorders. 54 61
11194712 2000
163
Reproductive hormones after pancreas transplantation. 54 61
11063337 2000
164
X-linked congenital adrenal hypoplasia: new mutations and long-term follow-up in three patients. 54 61
10931108 2000
165
Adipocyte insulin action in hypogonadotrophic hypogonadism. 54 61
10920084 2000
166
Prolonged activation of the hypothalamus-pituitary-gonadal axis in a child with X-linked adrenal hypoplasia congenita. 54 61
10931089 2000
167
Testosterone modulates serum leptin concentrations in a male patient with hypothalamic hypogonadism. 54 61
10853711 2000
168
Endocrine status in elderly men with lower urinary tract symptoms: correlation of age, hormonal status, and lower urinary tract function. The Prostate Study Group of the Austrian Society of Urology. 54 61
10699620 2000
169
Testosterone treatment in hypogonadal men: prostate-specific antigen level and risk of prostate cancer. 54 61
11421528 2000
170
Multiple endocrine abnormalities in a child with Blackfan-Diamond anemia and hemochromatosis. Significant improvement of growth velocity and predicted adult height following growth hormone treatment despite liver damage. 54 61
10714760 2000
171
Pulsatile luteinising hormone releasing hormone for ovulation induction in subfertility associated with polycystic ovary syndrome. 54 61
10796718 2000
172
[The significance of the androgen-estrogen ratios in the clinical picture of sexual disorders in men]. 54 61
10878975 2000
173
Prevalence of endocrine dysfunction in HIV-infected men. 54 61
11595820 2000
174
Fasting hyperinsulinemia in human immunodeficiency virus-infected men: relationship to body composition, gonadal function, and protease inhibitor use. 54 61
10634360 2000
175
[Pathologic manifestations of hormonal receptor mutations]. 54 61
10989556 2000
176
Obesity in the Prader-Labhart-Willi syndrome is not due to leptin deficiency but is accentuated by hypogonadism in male patients. 54 61
10619990 1999
177
Combined pituitary hormone deficiency: role of Pit-1 and Prop-1. 54 61
10626543 1999
178
The effects of treatment and the individual responsiveness to growth hormone (GH) replacement therapy in 665 GH-deficient adults. KIMS Study Group and the KIMS International Board. 54 61
10566630 1999
179
Male pseudohermaphroditism due to inactivating luteinizing hormone receptor mutations. 54 61
10714363 1999
180
Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects. 54 61
10523015 1999
181
Combined hypothalamic-pituitary-gonadal defect in a hypogonadic man with a novel mutation in the DAX-1 gene. 54 61
10522996 1999
182
Physiologic and genetic insights into the pathophysiology and management of hypogonadotropic hypogonadism. 54 61
10456179 1999
183
GH/IGF-I axis in azoospermia in primary and secondary hypogonadism: a study before and during replacement therapy. 54 61
10367239 1999
184
A microdeletion within DAX-1 in X-linked adrenal hypoplasia congenita and hypogonadotrophic hypogonadism. 54 61
10361383 1999
185
Relationship between hormone levels and testicular biopsies of azoospermic men. 54 61
10407645 1999
186
Clinical endocrinology of human leptin. 54 61
10193859 1999
187
The same molecular defects of the gonadotropin-releasing hormone receptor determine a variable degree of hypogonadism in affected kindred. 54 61
10022417 1999
188
Novel DAX1 mutations in X-linked adrenal hypoplasia congenita and hypogonadotrophic hypogonadism. 54 61
10341858 1999
189
Intracerebral Whipple's disease diagnosed by stereotactic biopsy: a case report and review of the literature. 54 61
9894983 1999
190
Effects of androgen administration on the growth hormone-insulin-like growth factor I axis in men with acquired immunodeficiency syndrome wasting. 54 61
9851759 1998
191
Effect of testosterone replacement on whole body glucose utilisation and other cardiovascular risk factors in males with idiopathic hypogonadotrophic hypogonadism. 54 61
9851674 1998
192
Pulsatile GnRH or human chorionic gonadotropin/human menopausal gonadotropin as effective treatment for men with hypogonadotropic hypogonadism: a review of 42 cases. 54 61
9758439 1998
193
Proteinuria, hypertension and chronic renal failure in X-linked Kallmann's syndrome, a defined genetic cause of solitary functioning kidney. 54 61
9719154 1998
194
Gonadotropin-releasing hormone receptor gene mutation: a new cause of hereditary hypogonadism and another mutated G-protein-coupled receptor. 54 61
9678526 1998
195
Hyperleptinaemia is associated with impaired gonadotrophin response to GnRH during late puberty in obese girls, not boys. 54 61
9678532 1998
196
Mid-follicular phase pulses of inhibin B are absent in polycystic ovarian syndrome and are initiated by successful laparoscopic ovarian diathermy: a possible mechanism regulating emergence of the dominant follicle. 54 61
9589683 1998
197
Hypothalamic amenorrhea and cardiovascular hormones: changes of plasma calcitonin gene-related peptide and atrial natriuretic peptide levels. 54 61
9624600 1998
198
A leptin missense mutation associated with hypogonadism and morbid obesity. 54 61
9500540 1998
199
Endocrine secretions under abnormal light-dark cycles and in the blind. 54 61
9550117 1998
200
[Disorders of gonadal function in hypothalamic-pituitary diseases]. 54 61
9396297 1997
201
Effects of leuprolide-induced hypogonadism and testosterone replacement on sleep, melatonin, and prolactin secretion in men. 54 61
9329339 1997
202
Short stature and failure of pubertal development in thalassaemia major: evidence for hypothalamic neurosecretory dysfunction of growth hormone secretion and defective pituitary gonadotropin secretion. 54 61
9365067 1997
203
Delayed puberty and hypogonadism caused by mutations in the follicle-stimulating hormone beta-subunit gene. 54 61
9271483 1997
204
Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene. 54 61
9207799 1997
205
Subcutaneous self-administration of highly purified follicle stimulating hormone and human chorionic gonadotrophin for the treatment of male hypogonadotrophic hypogonadism. Spanish Collaborative Group on Male Hypogonadotropic Hypogonadism. 54 61
9194651 1997
206
A functional determinant in human luteinizing hormone and chorionic gonadotropin: differential effect of mutations about beta-GLN-54. 54 61
9075724 1997
207
Adult-onset idiopathic hypogonadotropic hypogonadism--a treatable form of male infertility. 54 61
9010147 1997
208
The pituitary-gonadal axis and health in elderly men: a study of men born in 1913. 54 61
8866567 1996
209
Autoimmune polyglandular syndrome and primary biliary cirrhosis. 54 61
8983326 1996
210
[Endocrinologic problems of the male adolescent]. 54 61
9045225 1996
211
Testosterone-induced increase of insulin-like growth factor I levels depends upon normal levels of growth hormone. 54 61
8810735 1996
212
Endocrine screening for sexual dysfunction using free testosterone determinations. 54 61
8683690 1996
213
Serum levels of insulin-like growth factor I and insulin-like growth factor-binding protein 1 correlate with serum free testosterone and sex hormone binding globulin levels in healthy young and middle-aged men. 54 61
8801037 1996
214
Neuroendocrine mechanisms mediating awakening of the human gonadotropic axis in puberty. 54 61
8792395 1996
215
Severe ovarian hyperstimulation syndrome despite low plasma oestrogen concentrations in a hypogonadotrophic, hypogonadal patient. 54 61
8671418 1996
216
A family with an unusual myotonic and myopathic phenotype and no CTG expansion (proximal myotonic myopathy syndrome): a challenge for future molecular studies. 54 61
8784800 1996
217
Evidence for the Bauman variant in Kallmann's syndrome. 54 61
8706281 1996
218
[Delayed puberty and hypogonadotrophic hypogonadism: differential diagnosis with prolactin stimulation probe with chlorpromazine]. 54 61
8733264 1995
219
Evaluation of human chorionic gonadotropin stimulation tests in prepubertal and early pubertal boys. 54 61
8582400 1995
220
Alcoholic hypogonadism: hormonal response to clomiphene. 54 61
8590623 1995
221
Primary hypogonadism in females with infantile onset spinocerebellar ataxia. 54 61
8552218 1995
222
Identification of a putative steroidogenic factor-1 response element in the DAX-1 promoter. 54 61
7677767 1995
223
Isolated combined growth hormone and gonadotrophin deficiency due to hypothalamic dysfunction, associated with insulin resistance. 54 61
7554320 1995
224
Variable penetrance of hypogonadism in a sibship with Kallmann syndrome due to a deletion of the KAL gene. 54 61
7677154 1995
225
Hormonal substitution in older men. 54 61
7721255 1995
226
Changes in anterior pituitary response in patients with idiopathic hypothalamic hypogonadism caused by pulsatile GnRH therapy and testosterone replacement. 54 61
7584521 1995
227
Turner's syndrome and hypogonadotrophic hypogonadism: thalassemia major and hemochromatosis. 54 61
7584702 1995
228
Parathyroid hormone for the prevention of bone loss induced by estrogen deficiency. 54 61
7969342 1994
229
Hormonal therapy of male hypogonadism. 54 61
7705324 1994
230
[Endocrinological problems in male adolescents]. 54 61
7708535 1994
231
Diurnal rhythm of testosterone induced by human chorionic gonadotrophin (hCG) therapy in isolated hypogonadotrophic hypogonadism: a comparison between subcutaneous and intramuscular hCG administration. 54 61
8075787 1994
232
Gonadal function and response to human chorionic and menopausal gonadotrophin therapy in male patients with idiopathic hypogonadotrophic hypogonadism. 54 61
7914153 1994
233
Gene deletion causing adrenal hypoplasia congenita and hypogonadotrophic hypogonadism. 54 61
8033374 1994
234
Hyposomatomedinemia and hypogonadism in hemiplegic men who live in nursing homes. 54 61
8185456 1994
235
Male hypogonadism in myotonic dystrophy is related to (CTG)n triplet mutation. 54 61
8077624 1994
236
Endogenous opioids and hypogonadism in human obesity. 54 61
7922600 1994
237
Isolation and characterization of the gene responsible for the X chromosome-linked Kallmann syndrome. 54 61
7999985 1994
238
The direct pituitary effect of testosterone to inhibit gonadotropin secretion in men is partially mediated by aromatization to estradiol. 54 61
8188534 1994
239
Pulsatile administration of gonadotrophin releasing hormone as a diagnostic tool to distinguish hypothalamic from pituitary hypogonadism following neurosurgery. 54 61
8276962 1993
240
Pulsatile gonadotrophin releasing hormone versus gonadotrophin treatment of hypothalamic hypogonadism in males. 54 61
8276954 1993
241
Pulsatile GnRH treatment in boys and girls with idiopathic hypogonadotrophic hypogonadism. 54 61
8276956 1993
242
Environment, human reproduction, menopause, and andropause. 54 61
8243411 1993
243
Anterior pituitary function after adrenalectomy in patients with Cushing's syndrome. 54 61
8415342 1993
244
Familial insulin resistant diabetes associated with acanthosis nigricans, polycystic ovaries, hypogonadism, pigmentary retinopathy, labyrinthine deafness, and mental retardation. 54 61
8456839 1993
245
Regional obesity and NIDDM. 54 61
8249691 1993
246
[Heterogeneity of immunoreactive prolactin in hyperprolactinemia of various origin]. 54 61
1302839 1992
247
Excessive L-thyroxine therapy decreases femoral bone mineral densities in the male rat: effect of hypogonadism and calcitonin. 54 61
1456090 1992
248
Risk of osteoporosis in men with chronic bronchitis. 54 61
1392267 1992
249
Physiologic testosterone levels in normal men suppress high-density lipoprotein cholesterol levels. 54 61
1586105 1992
250
The role of treatment with growth hormone in infertile patients. 54 61
1424324 1992
251
Progressive high frequency hearing loss: an additional feature in the syndrome of congenital adrenal hypoplasia and gonadotrophin deficiency. 54 61
1601004 1992
252
Circadian rhythm of plasma testosterone in men with idiopathic hypogonadotrophic hypogonadism before and during pulsatile administration of gonadotrophin-releasing hormone. 54 61
1559297 1992
253
Pathophysiology of cancer: hormonal and metabolic abnormalities. 54 61
1461623 1992
254
Comparison of gonadotropin-releasing hormone and gonadotropin therapy in male patients with idiopathic hypothalamic hypogonadism. 54 61
1743335 1991
255
Subcutaneous gonadotropin therapy in male patients with hypogonadotropic hypogonadism. 54 61
1906410 1991
256
Simultaneous occurrence of SIADH, secondary hypogonadism and alopecia universalis in a woman with IDDM. 54 61
1666359 1991
257
Cushing's disease and hyperprolactinemia due to a mixed ACTH- and prolactin-secreting pituitary macroadenoma. 54 61
1656408 1991
258
[Metabolic cirrhosis (hemochromatosis, Wilson's disease, erythropoietic protoporphyria)]. 54 61
2063117 1991
259
Migratory arrest of gonadotropin-releasing hormone neurons in transgenic mice. 54 61
2014260 1991
260
Hypogonadism of male prolactinomas: relation to pulsatile secretion of LH. 54 61
2099670 1990
261
Sex hormone binding globulin: origin, function and clinical significance. 54 61
2080856 1990
262
Congenital cerebellar hypoplasia and hypogonadotropic hypogonadism. 54 61
2243234 1990
263
[The effect of acute ACTH1-24 loading on the steroid hormone and prolactin content of the blood serum in women with hyperprolactinemia and hyperandrogenism]. 54 61
2080142 1990
264
Induction of ovulation with pulsatile GnRH. 54 61
2282743 1990
265
[Pulsatile administration of gonadotropin releasing hormone in the female. Diagnostic and therapeutic indications]. 54 61
2143826 1990
266
Serum inhibin concentrations before and during gonadotropin treatment in men with hypogonadotropic hypogonadism: physiological and clinical implications. 54 61
2110576 1990
267
Hypogonadism and its treatment following ischaemic stroke in men with type 2 diabetes mellitus. 61
30064273 2020
268
The complex phenotype of spinocerebellar ataxia type 48 in eight unrelated Italian families. 61
31571321 2020
269
Long-term treatment with testosterone undecanoate injections in men with hypogonadism alleviates erectile dysfunction and reduces risk of major adverse cardiovascular events, prostate cancer, and mortality. 61
30782054 2020
270
Endocrinopathies complicating transfusion-dependent hemoglobinopathy. 61
32020146 2020
271
Low bone mineral density is associated with hypogonadism and cranial irradiation in male childhood cancer survivors. 61
32008156 2020
272
Pituitary Dysfunction after Radiation for Anterior Skull Base Malignancies: Incidence and Screening. 61
32021753 2020
273
Prolactinomas in pregnancy: considerations before conception and during pregnancy. 61
31792668 2020
274
The CHD4-related syndrome: a comprehensive investigation of the clinical spectrum, genotype-phenotype correlations, and molecular basis. 61
31388190 2020
275
Role of gut microbiota in sex- and diet-dependent metabolic disorders that lead to early mortality of androgen receptor-deficient male mice. 61
32017595 2020
276
Spontaneous fertility and variable spectrum of reproductive phenotype in a family with adult-onset X-linked adrenal insufficiency harboring a novel DAX-1/NR0B1 mutation. 61
32028936 2020
277
Prolactinomas and menopause: any changes in management? 61
31686376 2020
278
Traditional signs and symptoms commonly attributed to hypogonadism do not correlate with testosterone levels: the Cooper Center Longitudinal Study Experience. 61
31540967 2020
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Factors Affecting Loss to Follow-Up in Children and Adolescents with Chronic Endocrine Conditions. 61
32023623 2020
280
European Academy of Andrology (EAA) guidelines on investigation, treatment and monitoring of functional hypogonadism in males. 61
32026626 2020
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Hypogonadism is not being sufficiently recognised in 99% of general practices/family doctor surgeries. 61
31713967 2020
282
Stem Leydig Cells in the Adult Testis: Characterization, Regulation and Potential Applications. 61
31673697 2020
283
Prolactinomas in males: any differences? 61
31802331 2020
284
Congenital hypogonadotropic hypogonadism/Kallmann syndrome is associated with statural gain in both men and women: a monocentric study. 61
31770102 2020
285
Differentiation of human umbilical cord mesenchymal stem cells into Leydig-like cells with defined molecular compounds. 61
32034722 2020
286
Exon 3-deleted growth hormone receptor isoform is not related to worse bone mineral density or microarchitecture or to increased fracture risk in acromegaly. 61
31392573 2020
287
A novel splice site variant in ANOS1 gene leads to Kallmann syndrome in three siblings. 61
31669640 2020
288
Male hypogonadism: a review. 61
31988219 2020
289
Diabetes: a metabolic and reproductive disorder in women. 61
31635966 2020
290
Surgical management of clinically silent thyrotropin pituitary adenomas: A single center series of 20 patients. 61
31668712 2020
291
Long-term testosterone undecanoate replacement therapy: Impact of ethnicity. 61
31943322 2020
292
Re: Effects of Bariatric Surgery in Male Obesity-Associated Hypogonadism. 61
31625794 2020
293
Optimizing Aging Male Symptom Questionnaire Through Genetic Algorithms Based Machine Learning Techniques. 61
32009307 2020
294
Neuron-Derived Neurotrophic Factor Is Mutated in Congenital Hypogonadotropic Hypogonadism. 61
31883645 2020
295
Expanding the mutational spectrum of monogenic hypogonadotropic hypogonadism: novel mutations in ANOS1 and FGFR1 genes. 61
31996231 2020
296
An assessment of current penile prosthesis reimbursement guidelines for insurance plans nationwide. 61
31896830 2020
297
Symptoms of sexual dysfunction among men from infertile couples: prevalence and association with testosterone deficiency. 61
31325248 2020
298
Prevalence of endocrine complications in transfusion dependent thalassemia in Hospital Pulau Pinang: A pilot study. 61
32008017 2020
299
WDR11 is another causative gene for coloboma, cardiac anomaly and growth retardation in 10q26 deletion syndrome. 61
30711679 2020
300
An update on clinical, pathological, diagnostic, and therapeutic perspectives of childhood leukodystrophies. 61
31829048 2020
301
Testosterone Replacement Therapy for Patients with Hypogonadism after High Dose-Rate Brachytherapy for High-Risk Prostate Cancer: A Report of Six Cases and Literature Review. 61
31081296 2020
302
Effect of testosterone replacement therapy on sarcopenia: Case report of an older man with late-onset hypogonadism. 61
31916696 2020
303
Prolonged hormonal therapy and external beam radiation independently increase the risk of Persistent Hypogonadism in men treated with prostate brachytherapy. 61
31959519 2020
304
Increased Medical Complications, Revisions, In-Hospital Lengths of Stay, and Cost in Patients With Hypogonadism Undergoing Primary Total Knee Arthroplasty. 61
31542267 2020
305
FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. 61
31959736 2020
306
Opioid-induced endocrinopathies. 61
31624023 2020
307
Efficacy and Safety of Testosterone Treatment in Men: An Evidence Report for a Clinical Practice Guideline by the American College of Physicians. 61
31905375 2020
308
Anosmin-1 activates vascular endothelial growth factor receptor and its related signaling pathway for olfactory bulb angiogenesis. 61
31932617 2020
309
A single-nucleotide polymorphism induced alternative splicing in Tacr3 involves in hypoxic-ischemic brain damage. 61
31722250 2020
310
Characterization of the human GnRH neuron developmental transcriptome using a GNRH1-TdTomato reporter line in human pluripotent stem cells. 61
31996360 2020
311
Late-Onset Hypogonadism and Lifestyle-Related Metabolic Disorders. 61
31991053 2020
312
Fertility issues in aggressive pituitary tumors. 61
31984458 2020
313
Identification of ROBO1/2 and SCEL as candidate genes in Kallmann syndrome with emerging bioinformatic analysis. 61
31325086 2020
314
Mutations within The Transcription Factor PROP1 in a Cohort of Turkish Patients with Combined Pituitary Hormone Deficiency 61
31948187 2020
315
CTG expansion in the DMPK gene: semen quality assessment and outcome of Preimplantation Genetic Diagnosis. 61
31996899 2020
316
Genotypic and phenotypic spectra of FGFR1, FGF8, and FGF17 mutations in a Chinese cohort with idiopathic hypogonadotropic hypogonadism. 61
31748124 2020
317
Monoamino oxidase alleles correlate with the presence of essential hypertension among hypogonadic patients. 61
31743621 2020
318
Testosterone Therapy in Relation to Prostate Cancer in a U.S. Commercial Insurance Claims Database. 61
31641011 2020
319
A novel missense variant in the BBS7 gene underlying Bardet-Biedl syndrome in a consanguineous Pakistani family. 61
31469663 2020
320
Multiple genetic mutations implicate spectrum of phenotypes in Bardet-Biedl syndrome. 61
31639430 2020
321
European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity. 61
31855556 2020
322
Diagnosis and Management of Intratubular Germ Cell Neoplasia in Situ: A Systematic Review. 61
31967523 2020
323
Reproductive health issues in female patients with beta-thalassaemia major: a narrative literature review. 61
31999213 2020
324
Klinefelter syndrome and testosterone treatment: a national cohort study on thrombosis risk. 61
31829966 2020
325
A report of congenital adrenal hyperplasia due to 17α-hydroxylase deficiency in two 46,XX sisters. 61
31464148 2020
326
Prevalence of endocrine disorders in obese patients: systematic review and meta-analysis. 61
31652416 2020
327
46,XX male disorder of sexual development. 61
32029971 2020
328
Study of expression of genes potentially responsible for reduced fitness in patients with myotonic dystrophy type 1 and identification of new biomarkers of testicular function. 61
31840338 2020
329
Age-related presence of spermatogonia in patients with Klinefelter syndrome: a systematic review and meta-analysis. 61
31822886 2020
330
Testosterone Therapy: What We Have Learned From Trials. 61
31928918 2020
331
Trends and Patterns of Testosterone Therapy Among US Male Medicare Beneficiaries, 1999-2014. 61
31928462 2020
332
Weight loss more than glycemic control may improve testosterone in obese type 2 diabetes mellitus men with hypogonadism. 61
31919991 2020
333
(D)evolving attitudes toward late onset hypogonadism. 61
32033739 2020
334
Testosterone Management in Aging Males: Surveying Clinical Practices of Urologists and Endocrinologists in Israel. 61
31400964 2019
335
Changes in protein function underlie the disease spectrum in patients with CHIP mutations. 61
31619515 2019
336
Perrault syndrome with amenorrhea, infertility, Tarlov cyst, and degenerative disc. 61
31274036 2019
337
A novel truncating variant in ring finger protein 113A (RNF113A) confirms the association of this gene with X-linked trichothiodystrophy. 61
31880405 2019
338
Induced pluripotent stem cells (iPSCs) derived from a renpenning syndrome patient with c.459_462delAGAG mutation in PQBP1 (PEIi001-A). 61
31698189 2019
339
Bardet-Biedl Syndrome in rhesus macaques: A nonhuman primate model of retinitis pigmentosa. 61
31589838 2019
340
Prevalence of endocrine disorders and their associated factors in transfusion-dependent thalassemia patients: a historical cohort study in Southern Iran. 61
31228105 2019
341
Acute effects of insulin on skeletal muscle growth and differentiation genes in men with type 2 diabetes. 61
31618707 2019
342
Male and female sexual dysfunction in diabetic subjects: Focus on new antihyperglycemic drugs. 61
31863254 2019
343
Clinicopathologic Characteristics and Endoscopic Surgical Outcomes of Symptomatic Rathke's Cleft Cysts. 61
31493602 2019
344
Management of ovulation induction and intrauterine insemination in infertile patients with hypogonadotropic hypogonadism. 61
30930300 2019
345
Opioid-induced hypogonadism: Pathophysiology, clinical and therapeutics review. 61
31886562 2019
346
Frequency of Hypogonadism in Type 2 Diabetes Mellitus Patients with and without Coronary Artery Disease. 61
32025421 2019
347
Novel synonymous and missense variants in FGFR1 causing Hartsfield syndrome. 61
31512363 2019
348
A case of Kallmann syndrome associated to a novel missense mutation of the FGFR1 gene. 61
31910188 2019
349
Evaluation of endocrine complications in beta-thalassemia intermedia (β-TI): a cross-sectional multicenter study. 61
31853840 2019
350
Re: Adverse Health Outcomes in Relationship to Hypogonadism after Chemotherapy: A Multicenter Study of Testicular Cancer Survivors. 61
31512965 2019
351
Re: Increased Medical Complications, Revisions, In-Hospital Lengths of Stay, and Cost in Patients with Hypogonadism Undergoing Primary Total Knee Arthroplasty. 61
31821074 2019
352
Re: Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study. 61
31821075 2019
353
The Role of Diet and Weight Loss in Improving Secondary Hypogonadism in Men with Obesity with or without Type 2 Diabetes Mellitus. 61
31817436 2019
354
Influence of testosterone substitution on glycemic control and endothelial markers in men with newly diagnosed functional hypogonadism and type 2 diabetes mellitus: a randomized controlled trial. 61
30235049 2019
355
HASPIN kinase inhibitor CHR-6494 suppresses intestinal polyp development, cachexia, and hypogonadism in Apcmin/+ mice. 61
31833958 2019
356
Hypogonadism in Pediatric Health: Adult Medicine Concepts Fail. 61
31471249 2019
357
The PROK2/PROKR2 signaling pathway is required for the migration of most olfactory bulb interneurons. 61
31132148 2019
358
Testicular Cancer Survivorship. 61
31805527 2019
359
Effect of education about andropause health on level of the knowledge and attitude of men referring to the education and training retirement center of Shiraz. 61
31793386 2019
360
Testicular Function of Childhood Cancer Survivors: Who Is Worse? 61
31847212 2019
361
Effects of transdermal administration of testosterone gel on the urinary steroid profile in hypogonadal men: Implications in antidoping analysis. 61
31499075 2019
362
Endocrinopathies and cancer cachexia. 61
31567482 2019
363
Testosterone replacement therapy is associated with an increased risk of urolithiasis. 61
30903351 2019
364
Testosterone Therapy in Adolescent Boys: The Need for a Structured Approach. 61
31851967 2019
365
Hyperprolactinaemia. 61
31847209 2019
366
Primary aldosteronism in Klinefelter's syndrome: two cases. 61
31841437 2019
367
Testosterone Increases the Expression and Phosphorylation of AMP kinase α in Men with Hypogonadism and Type 2 Diabetes. 61
31858126 2019
368
FSH treatment of male idiopathic infertility: Time for a paradigm change. 61
31872552 2019
369
Digit ratio (2D:4D) and testosterone supplementation. 61
31493670 2019
370
Hypogonadism and prostate cancer detection on multiparametric MRI and mpMRI-TRUS fusion biopsy. 61
31807974 2019
371
Testosterone, testosterone therapy and prostate cancer. 61
30614347 2019
372
Identification of KISS1R gene mutations in disorders of non-obstructive azoospermia in the northeast population of China. 61
31821609 2019
373
Management of Hypopituitarism. 61
31817511 2019
374
Cre/lox generation of a novel whole-body Kiss1r KO mouse line recapitulates a hypogonadal, obese, and metabolically-impaired phenotype. 61
31442544 2019
375
Kallmann Syndrome with Syndactyly. 61
31779756 2019
376
The spectrum of clinical and subclinical endocrinopathies in treatment-naïve patients with celiac disease. 61
31879833 2019
377
The effects of age and obesity on postprandial dynamics of serum testosterone levels in men. 61
31821582 2019
378
Quantitative Analysis of the Seminal Plasma Proteome in Secondary Hypogonadism. 61
31816910 2019
379
Monitoring testosterone replacement therapy with transdermal gel: when and how? 61
31267510 2019
380
Effects of hypogonadism on brain development during adolescence in girls with Turner syndrome. 61
31389646 2019
381
Reduced uterine volume after induction of puberty in women with hypogonadism. 61
31487390 2019
382
Misuse of testosterone replacement therapy in men in infertile couples and its influence on infertility treatment. 61
31739658 2019
383
A Phenotypic Female Adolescent with Primary Amenorrhea and Dysmorphic Features. 61
31830290 2019
384
Pituitary gland recovery following fully endoscopic transsphenoidal surgery for nonfunctioning pituitary adenoma: results of a prospective multicenter study. 61
31731279 2019
385
A case of premature ovarian insufficiency in Nijmegen breakage syndrome patient and review of literature. From gene mutation to clinical management. 61
31187634 2019
386
Obesity and metabolic syndrome associated with systemic inflammation and the impact on the male reproductive system. 61
31373727 2019
387
Overt Hypogonadism May Not Be a Sentinel Sign of RING Finger Protein 216: Two Novel Mutations Associated with Ataxia, Chorea, and Fertility. 61
31745488 2019
388
Pituitary Dysfunction Among Men Presenting with Hypogonadism. 61
31734886 2019
389
Efficacy of follitropin-alpha versus human menopausal gonadotropin for male patients with congenital hypogonadotropic hypogonadism. 61
31905120 2019
390
Evaluation of gonadotropin-replacement therapy in male patients with hypogonadotropic hypogonadism. 61
31062720 2019
391
Impact of hypogonadotropic hypogonadism on ovarian reserve and response. 61
31625035 2019
392
Testosterone levels after treatment with urofollitropin in infertile patients with idiopathic mild reduction of testicular volume. 61
31240459 2019
393
BBS5 and INPP5E mutations associated with ciliopathy disorders in families from Pakistan. 61
31173343 2019
394
Woodhouse-Sakati Syndrome: First report of a Portuguese case. 61
31347785 2019
395
A novel DCAF17 homozygous mutation in a girl with Woodhouse-Sakati syndrome and review of the current literature. 61
31472064 2019
396
Phenotypic spectrum of idiopathic hypogonadotropic hypogonadism patients with CHD7 variants from a large Chinese cohort. 61
31689711 2019
397
Prader-Willi syndrome and Angelman syndrome: Visualisation of the molecular pathways for two chromosomal disorders. 61
29425059 2019
398
An approach that someday may boost testosterone biosynthesis in males with late-onset hypogonadism (low testosterone). 61
31653760 2019
399
Long-Term Safety and Efficacy of Clomiphene Citrate for the Treatment of Hypogonadism. 61
31216250 2019
400
Association of Testosterone Therapy With Risk of Venous Thromboembolism Among Men With and Without Hypogonadism. 61
31710339 2019
401
Male sickle cell patients, compensated transpubertal hypogonadism and normal final growth. 61
31408198 2019
402
Aromatase inhibitors and selective estrogen receptor modulators: Unconventional therapies for functional hypogonadism? 61
31696669 2019
403
The effects of hypogonadism on quality of life in survivors of germ cell tumors treated with surgery alone versus surgery plus platinum-based chemotherapy. 61
31707501 2019
404
Expanding the clinical and molecular spectrum of the CWC27-related spliceosomopathy. 61
31481716 2019
405
Directing differentiation of human induced pluripotent stem cells toward androgen-producing Leydig cells rather than adrenal cells. 61
31591190 2019
406
Modulatory effects of ghrelin on sperm quality alterations induced by a fructose-enriched diet. 61
31844755 2019
407
Is Testosterone Replacement Therapy in Older Men Effective and Safe? 61
31595418 2019
408
Leydig cell failure with testicular radiation doses <20Gy: The clinical effects of total body irradiation conditioned haematopoietic stem cell transplantation for childhood leukaemia during long-term follow-up. 61
31295360 2019
409
Low serum testosterone levels and the incidence of chronic kidney disease among male adults: A prospective population-based study. 61
31697870 2019
410
Three Siblings with Idiopathic Hypogonadotropic Hypogonadism in a Nonconsanguineous Family: A Novel KISS1R/GPR54 Loss-of-Function Mutation 61
30905142 2019
411
Hypogonadotrophic hypogonadism, delayed puberty and risk for neurodevelopmental disorders. 61
31630461 2019
412
mTOR and autophagy pathways are dysregulated in murine and human models of Schaaf-Yang syndrome. 61
31685878 2019
413
Prevention and management of osteoporosis and osteoporotic fractures in persons with a spinal cord injury or disorder: A systematic scoping review. 61
29745791 2019
414
Laboratory evaluation of secondary causes of bone loss in Veterans with spinal cord injury and disorders. 61
31410501 2019
415
Clinical characterization of men with long QT syndrome and torsades de pointes associated with hypogonadism: A review and pharmacovigilance study. 61
31477476 2019
416
Mechanistic insights into the aetiology of post-prandial decline in testosterone in reproductive-aged men. 61
31475727 2019
417
Gender differences and temporal trends over two decades in acromegaly: a single center study in 112 patients. 61
31677093 2019
418
Relationships between eating disorder psychopathology, sexual hormones and sexual behaviours. 61
31026479 2019
419
Adverse Effects of Common Sports and Recreational Activities on Male Reproduction. 61
29731401 2019
420
ESR1 polymorphism (rs2234693) influences femoral bone mass in patients with Turner syndrome. 61
31671406 2019
421
Endocrine-related adverse events associated with immune-checkpoint inhibitors in patients with melanoma. 61
31518074 2019
422
Sulforaphane Protects the Male Reproductive System of Mice from Obesity-Induced Damage: Involvement of Oxidative Stress and Autophagy. 61
31591291 2019
423
A Descriptive Study to Find Possible Correlation between Pituitary Magnetic Resonance Image Findings and Abnormal Pituitary Hormones: A Retrospective Single Centre Study in Saudi Community Based Hospital. 61
31571448 2019
424
Factors predicting endocrine late effects in childhood cancer survivors from a Japanese hospital. 61
31656261 2019
425
Diet and Female Sexual Health. 61
31669123 2019
426
A Clinical Perspective of Sleep and Andrological Health: Assessment, Treatment Considerations, and Future Research. 61
31042277 2019
427
Delayed-onset adrenal hypoplasia congenita and hypogonadotropic hypogonadism caused by a novel mutation in DAX1. 61
31642359 2019
428
Noninvasive evaluation of anterior segment and tear film parameters and morphology of meibomian glands in a pediatric population with hypogonadism. 61
31499236 2019
429
Review of Hormone Replacement Therapy in Girls and Adolescents with Hypogonadism. 61
31059821 2019
430
Longitudinal changes in bone density in adolescents and young adults with cerebral palsy: A case for early intervention. 61
31246317 2019
431
Oncological safety of testosterone replacement therapy in prostate cancer survivors after definitive local therapy: A systematic literature review and meta-analysis. 61
31296421 2019
432
Fertility in Adolescents with Klinefelter Syndrome: A Survey of Current Clinical Practice. 61
31608942 2019
433
Chronic testosterone deprivation sensitizes the middle-aged rat brain to damaging effects of testosterone replacement. 61
31671430 2019
434
Insights into the molecular regulatory network of pathomechanisms in osteochondroma. 61
31211456 2019
435
A TAC3 Missense Variant in a Domestic Shorthair Cat with Testicular Hypoplasia and Persistent Primary Dentition. 61
31615056 2019
436
A novel heterozygous intron mutation in SEMA7A causing kallmann syndrome in a female. 61
31650878 2019
437
A de novo frameshift FGFR1 mutation extending the protein in an individual with multiple epiphyseal dysplasia and hypogonadotropic hypogonadism without anosmia. 61
31605817 2019
438
Addressing gaps in care of people with conditions affecting sex development and maturation. 61
31406344 2019
439
Gender Affirming Hormone Replacement for the Adolescent and Young Adult Cancer Survivor with Hypogonadism. 61
31580768 2019
440
Rln3a is a prerequisite for spermatogenesis and fertility in male fish. 61
31678357 2019
441
Autoimmune phenomena involving the pituitary gland in children: New developing data about diagnosis and treatment. 61
31401342 2019
442
Cystic fibrosis bone disease treatment: Current knowledge and future directions. 61
31679730 2019
443
Primary Bullous Keratopathy in a Patient With Werner Syndrome Treated With Corneal Transplant. 61
29534662 2019
444
A review of hypogonadotropic hypogonadism cases followed up in our clinic in the last decade. 61
31622170 2019
445
Understanding the functions of kisspeptin and kisspeptin receptor (Kiss1R) from clinical case studies. 61
30339828 2019
446
Thyroid function in Klinefelter syndrome: a multicentre study from KING group. 61
30912057 2019
447
Slipped Capital Femoral Epiphysis in an Adult Patient With Kabuki Syndrome. 61
31773073 2019
448
Recognizable type of pituitary, heart, kidney and skeletal dysplasia mostly caused by SEMA3A mutation: A case report. 61
31667184 2019
449
Androgens and Androgen Receptor Actions on Bone Health and Disease: From Androgen Deficiency to Androgen Therapy. 61
31731497 2019
450
Correlation of anti-Mullerian hormone with humanchorionic gonadotropin test in the evaluation of testicular function of children with 46 XY male hypogonadism: Use of anti-Mullerian hormone as abiomarker. 61
31614067 2019
451
MY-T study: Symptom-based titration decisions when using testosterone nasal gel, Natesto®. 61
31364978 2019
452
ENDOCRINOLOGY AND ADOLESCENCE: Dealing with transition in young patients with pituitary disorders. 61
31370006 2019
453
Late-onset hypogonadism: a concept comes of age. 61
31639279 2019
454
A systematic review and meta-analysis of clinical trials implementing aromatase inhibitors to treat male infertility. 61
31621654 2019
455
Turner syndrome: mechanisms and management. 61
31213699 2019
456
Bone Densitometry in Transgender and Gender Non-Conforming (TGNC) Individuals: 2019 ISCD Official Position. 61
31327665 2019
457
A rare case of obesity. Can it be Bardet-Biedl Syndrome? 61
31534736 2019
458
[A comparative characteristics of treatment results of patiens with benign prostatic hyperplasia in combination with hypogonadism]. 61
31535806 2019
459
Neural Crest Cell Failure as Embryogenesis for Fusiform Aneurysm of the Anterior Communicating Artery: Case Report and Review of the Literature. 61
31203061 2019
460
Syndromic infertility. 61
31577259 2019
461
POEMS syndrome: a rare cause of adrenal insufficiency in a young male. 61
31967972 2019
462
History of cerebral localization and the emigration plight of three neuroscience giants from Nazi Germany: Josef Gerstmann, Adolf Wallenberg, and Franz Josef Kallmann. 61
31473673 2019
463
Opioids and their endocrine effects: A systematic review and meta-analysis. 61
31511863 2019
464
Case report of 49,XXXXY syndrome with cleft palate, diabetes, hypothyroidism, and cataracts. 61
31574874 2019
465
Laurence-Moon-Bardet-Biedl Syndrome: A Case Report. 61
31696011 2019
466
Opioid-Induced Hypogonadism in the United States. 61
31485565 2019
467
Late-onset hypogonadism: metabolic impact. 61
31502758 2019
468
Efficacy of combined treatment of intramuscular testosterone injection and testosterone ointment application for late-onset hypogonadism: an open-labeled, randomized, crossover study. 61
31532277 2019
469
Adjuvant carboplatin therapy in patients with clinical stage 1 testicular seminoma: is long-term morbidity increased? 61
31286241 2019
470
Ciliochoroidal effusion syndrome with central serous-like chorioretinopathy and secondary angle closure following exogenous testosterone use. 61
31198887 2019
471
Melatonin appears to protect against steroidogenic collapse in both mice fed with high-fat diet and H2 O2 -treated TM3 cells. 61
31134680 2019
472
Cardiovascular and Cerebrovascular Safety of Testosterone Replacement Therapy Among Aging Men with Low Testosterone Levels: A Cohort Study. 61
30953635 2019
473
PITUITARY IMAGING BY MRI AND ITS CORRELATION WITH BIOCHEMICAL PARAMETERS IN THE EVALUATION OF MEN WITH HYPOGONADOTROPIC HYPOGONADISM. 61
31170366 2019
474
Characteristic dynamics of height and weight in preschool boys with constitutional delay of growth and puberty or hypogonadotropic hypogonadism. 61
31211864 2019
475
Association between duration of obesity and severity of ovarian dysfunction in rat-cafeteria diet approach. 61
31349120 2019
476
Gonadal hormone-dependent vs. -independent effects of kisspeptin signaling in the control of body weight and metabolic homeostasis. 61
31226351 2019
477
Deletion of the Homeodomain Protein Six6 From GnRH Neurons Decreases GnRH Gene Expression, Resulting in Infertility. 61
31211355 2019
478
[Autoimmune polyglandular disorders in myotonic dystrophy]. 61
31566311 2019
479
Targeted Gene Panel Sequencing for Molecular Diagnosis of Kallmann Syndrome and Normosmic Idiopathic Hypogonadotropic Hypogonadism. 61
30216942 2019
480
The Global Prader-Willi Syndrome Registry: Development, Launch, and Early Demographics. 61
31540108 2019
481
Impact of genetic subtypes of Prader-Willi syndrome with growth hormone therapy on intelligence and body mass index. 61
31313492 2019
482
Testosterone Replacement Therapy and the Risk of Prostate Cancer in Men With Late-Onset Hypogonadism. 61
31145457 2019
483
Androgenic Effects on Ventricular Repolarization: A Translational Study From the International Pharmacovigilance Database to iPSC-Cardiomyocytes. 61
31378084 2019
484
CRISPR/dCas9-mediated activation of multiple endogenous target genes directly converts human foreskin fibroblasts into Leydig-like cells. 61
31264792 2019
485
Mechanism and chain specificity of RNF216/TRIAD3, the ubiquitin ligase mutated in Gordon Holmes syndrome. 61
31087003 2019
486
Despite Genetic Iron Overload, Hfe-Hemochromatosis Mice Do Not Show Bone Loss. 61
31667458 2019
487
[Cerebral palsy associated urological pathologies. Nurse´s role.] 61
31475673 2019
488
Association Between Post-Ejaculatory Refractory Time (PERT) and Premature Ejaculation (PE). 61
31405769 2019
489
Fucoxanthin-Rich Brown Algae Extract Improves Male Reproductive Function on Streptozotocin-Nicotinamide-Induced Diabetic Rat Model. 61
31514311 2019
490
Investigation and management of subfertility. 61
31296604 2019
491
Human Chorionic Gonadotropin monotherapy for the treatment of hypogonadal symptoms in men with total testosterone > 300 ng/dL. 61
31408289 2019
492
Growth hormone secretion, fatigue and quality of life after childhood traumatic brain injury. 61
31319378 2019
493
Efficacy and safety of fractionated conformal radiation therapy in acromegaly: a long-term follow-up study. 61
31098940 2019
494
Male Obesity-related Secondary Hypogonadism - Pathophysiology, Clinical Implications and Management. 61
31616498 2019
495
Novel mutations and spectrum of the disease of NR0B1 (DAX1)-related adrenal insufficiency in Indian children. 61
31219797 2019
496
Novel frameshift mutation of the NR0B1(DAX1) in two tall adult brothers. 61
31280422 2019
497
Angiotensin blockade attenuates diabetic nephropathy in hypogonadal adult male rats. 61
30970225 2019
498
Pathogenic variants in USP7 cause a neurodevelopmental disorder with speech delays, altered behavior, and neurologic anomalies. 61
30679821 2019
499
New insights into human prolactin pathophysiology: genomics and beyond. 61
31045655 2019
500
Functional Hypogonadotropic Hypogonadism in Men: Underlying Neuroendocrine Mechanisms and Natural History. 61
31220265 2019
501
Possible role of androgen receptor gene in therapeutic response of infertile men with hypogonadotropic hypogonadism. 61
31030566 2019
502
New genetic findings in a large cohort of congenital hypogonadotropic hypogonadism. 61
31200363 2019
503
Optimal treatment for spermatogenesis in male patients with hypogonadotropic hypogonadism. 61
31374027 2019
504
Metastatic MEN1 Syndrome Treated with Lutetium-177 - A Case Report. 61
31616499 2019
505
A case of Woodhouse-Sakati syndrome with pituitary iron deposition, cardiac and intestinal anomalies, with a novel mutation in DCAF17. 61
31152917 2019
506
Testosterone for Androgen Deficiency-Like Symptoms in Men Without Pathologic Hypogonadism: A Randomized, Placebo-Controlled Cross-Over with Masked Choice Extension Clinical Trial. 61
31425577 2019
507
Synthesis and biological evaluation of methylpyrimidine-fused tricyclic diterpene analogs as novel oral anti-late-onset hypogonadism agents. 61
31091478 2019
508
Hypogonadism in Men With Hepatitis C: What Is a Clinician to Do? 61
30715228 2019
509
Sperm Count and Hypogonadism as Markers of General Male Health. 61
31427194 2019
510
High-Density Lipoprotein Function Is Reduced in Patients Affected by Genetic or Idiopathic Hypogonadism. 61
30835274 2019
511
Changes in total sperm count after gastric bypass and sleeve gastrectomy: the BARIASPERM prospective study. 61
31147284 2019
512
The Link between Estradiol and Neuroplasticity in Transgender Women after Gender-affirming Surgery: a Bimodal Hypothesis. 61
31461715 2019
513
Identification of a pituitary ERα-activated enhancer triggering the expression of Nr5a1, the earliest gonadotrope lineage-specific transcription factor. 61
31391075 2019
514
Treatment of Functional Hypogonadism Besides Pharmacological Substitution. 61
31496147 2019
515
Adrenal morphology and associated comorbidities in congenital adrenal hyperplasia. 61
31001843 2019
516
[Differential diagnoses of osteoporosis]. 61
31297588 2019
517
Gonadotropin treatment for male partial congenital hypogonadotropic hypogonadism in Chinese patients. 61
31464203 2019
518
A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2. 61
31219578 2019
519
Pituitary involvement in patients with granulomatosis with polyangiitis: case series and literature review. 61
31203400 2019
520
Conversion of human fibroblasts into functional Leydig-like cells by small molecules and a single factor. 61
31182281 2019
521
Obesity and male hypogonadism: Tales of a vicious cycle. 61
31035310 2019
522
Erectile Dysfunction: A Primer for in Office Management. 61
31470566 2019
523
Exome Sequencing of a Primary Ovarian Insufficiency Cohort Reveals Common Molecular Etiologies for a Spectrum of Disease. 61
31042289 2019
524
Effects of Bariatric Surgery in Male Obesity-Associated Hypogonadism. 61
31065918 2019
525
Panhypopituitarism- An unusual presenation of tuberculous meningitis. 61
31439193 2019
526
Lack of Improvement of Sperm Characteristics in Obese Males After Obesity Surgery Despite the Beneficial Changes Observed in Reproductive Hormones. 61
30806913 2019
527
A Rare Case of Swyer Syndrome in Two Sisters with Successful Pregnancy Outcome in Both. 61
31576088 2019
528
Pituitary magnetic resonance imaging abnormalities in young female patients with hypogonadotropic hypogonadism. 61
31338342 2019
529
Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism. 61
31291191 2019
530
RF9: May it be a new therapeutic option for hypogonadotropic hypogonadism? 61
31203909 2019
531
Isolated Hypogonadotropic Hypogonadism Secondary to Anti-Programmed Death Ligand 1 Inhibitor. 61
31235040 2019
532
Late-onset hypogonadism (LOH), masculinity and relationship and sexual satisfaction: are sexual symptoms of LOH mediators of traditional masculinity on relationship and sexual satisfaction? 61
31287968 2019
533
Androgen deficiency in older men. 61
31256511 2019
534
Reversible male hypogonadotropic hypogonadism due to energy deficit. 61
30903626 2019
535
Contribution of Liver Fat to Weight Loss-Induced Changes in Serum Hepatokines: A Randomized Controlled Trial. 61
30753672 2019
536
Severe hypoglycemia and hyponatremia caused by hypopituitarism in a female patient with type 1 diabetes: A case report. 61
31305453 2019
537
[Reflexions on 50 Years of Sexual Medicine in Urology Focusing on Male Sexual Dysfunctions]. 61
31342492 2019
538
Testosterone undecanoate supplementation together with human chorionic gonadotropin does not impair spermatogenesis in males with isolated hypogonadotropic hypogonadism: a retrospective study. 61
30604694 2019
539
Possibility of early diagnosis in a fetus affected by Prader‑Willi syndrome with maternal hetero‑UPD15: A lesson to be learned. 61
31115529 2019
540
Ovotesticular Disorder of Sex Development: A Rare Case of Lateral Subtype 45X/46XY kariotype Diagnosed in Adulthood. 61
31005658 2019
541
Comparison of Anthropometric Measures for Evaluating the Association Between Hypogonadism and Hypothalamic-Pituitary-Gonadal Hormones in a Taiwanese Population. 61
31084407 2019
542
Effects of SHBG rs1799941 Polymorphism on Free Testosterone Levels and Hypogonadism Risk in Young Non-Diabetic Obese Males. 61
31370189 2019
543
Late-onset Hypogonadism and Testosterone Therapy - A Summary of Guidelines from the American Urological Association and the European Association of Urology. 61
30858073 2019
544
Chronic high-dose testosterone treatment: impact on rat cardiac contractile biology. 61
31353833 2019
545
Measuring testosterone in women and men. 61
31133215 2019
546
Klinefelter Syndrome and Diabetes. 61
31367971 2019
547
Kisspeptin recombinant oral vaccine: A master gene vaccine inhibiting the reproductive physiology and behavior of ram lambs. 61
29097006 2019
548
Combined Pituitary Hormone Deficiency Caused by a Synonymous HESX1 Gene Mutation. 61
30888394 2019
549
S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation. 61
31265437 2019
550
Oocyte quality in women with thalassaemia major: insights from IVF cycles. 61
31404374 2019
551
A 10-year longitudinal study of evaluation of ovarian reserve in women with transfusion-dependent beta thalassaemia major. 61
31082742 2019
552
Why Do Normal Children Have Acromegalic Levels of IGF-I During Puberty? 61
30840065 2019
553
Metabolic Effects of Testosterone Therapy in Men with Type 2 Diabetes and Metabolic Syndrome. 61
30803918 2019
554
Insulin-like factor 3, luteinizing hormone and testosterone in testicular cancer patients: effects of β-hCG and cancer treatment. 61
30609309 2019
555
Neuropsychiatric and Behavioral Involvement in AAS Abusers. A Literature Review. 61
31336641 2019
556
Challenges in the Diagnosis of Medulloblastoma Recurrence at an Unusual Site in a Patient With Prader-Willi Syndrome. 61
31306337 2019
557
Pheochromocytoma, paragangliomas, and pituitary adenoma: An unusual association in a patient with an SDHD mutation. Case report. 61
31348302 2019
558
Association of bifid epiglottis and laryngeal web with Bardet-Biedl syndrome: A case report. 61
31022684 2019
559
Male hypogonadism: 14-year prospective outcome in 550 men with type 2 diabetes. 61
31294081 2019
560
Dietary vs. pharmacological doses of zinc: A clinical review. 61
31303527 2019
561
MECHANISMS IN ENDOCRINOLOGY: Estradiol as a male hormone. 61
31096185 2019
562
Pubertal and Adult Testicular Functions in Nonclassic Lipoid Congenital Adrenal Hyperplasia: A Case Series and Review. 61
31286101 2019
563
Replacement of Male Mini-Puberty. 61
31240270 2019
564
46,XX Testicular Disorder of Sex Development (DSD): A Case Report and Systematic Review. 61
31336995 2019
565
Genotypic and phenotypic spectra of hemojuvelin mutations in primary hemochromatosis patients: a systematic review. 61
31286966 2019
566
Testicular ultrasound inhomogeneity is an informative parameter for fertility evaluation. 61
31274478 2019
567
An industry update in therapeutics: what is the latest news? 61
31232184 2019
568
Mayer-Rokitansky-Küster-Hauser syndrome with a uterine cervix and normal vagina associated with gonadal dysgenesis in a 46,XX female. 61
30912224 2019
569
Presentation, Morbidity and Treatment Outcome of Acromegaly Patients at a Single Centre. 61
31741902 2019
570
Germ cell arrest associated with aSETX mutation in ataxia oculomotor apraxia type 2. 61
30642639 2019
571
[Manifestation of Graves' disease, resulting from radiosurgical treatment of acromegaly, in a patient with panhypopituitarism]. 61
31271712 2019
572
Laurence-Moon-Bardet-Biedl Syndrome with Coexisting Abdominal Distension and Positive Fluid Thrill: A Rare Manifestation Reported in Karachi, Pakistan. 61
31497414 2019
573
Detailed retinal phenotype of Boucher-Neuhäuser syndrome associated with mutations in PNPLA6 mimicking choroideremia. 61
31135245 2019
574
Prevalence and Course of Endocrinopathy in POEMS Syndrome. 61
30239770 2019
575
Functional analysis of SOX10 mutations identified in Chinese patients with Kallmann syndrome. 61
30914325 2019
576
The changing burden of long-term health outcomes in survivors of childhood acute lymphoblastic leukaemia: a retrospective analysis of the St Jude Lifetime Cohort Study. 61
31078468 2019
577
NAFLD in Some Common Endocrine Diseases: Prevalence, Pathophysiology, and Principles of Diagnosis and Management. 61
31212642 2019
578
Effect of Testosterone on FGF2, MRF4, and Myostatin in Hypogonadotropic Hypogonadism: Relevance to Muscle Growth. 61
30629183 2019
579
Constitutional delay of puberty versus congenital hypogonadotropic hypogonadism: Genetics, management and updates. 61
31522908 2019
580
A comprehensive diagnostic approach to detect underlying causes of obesity in adults. 61
30821060 2019
581
Isolated hypoaldosteronism as first sign of X-linked adrenal hypoplasia congenita caused by a novel mutation in NR0B1/DAX-1 gene: a case report. 61
31164167 2019
582
Testosterone Therapy in Men With Hypogonadism Prevents Progression From Prediabetes to Type 2 Diabetes: Eight-Year Data From a Registry Study. 61
30862651 2019
583
The impact of childhood cancer and its treatment on puberty and subsequent hypothalamic pituitary and gonadal function, in both boys and girls. 61
31327697 2019
584
Early puberty in end stage renal failure and renal transplant recipients. 61
31141486 2019
585
Benefits and risks of testosterone therapy in older men. 61
30700083 2019
586
ENDOCRINE HISTORY: The history of discovery, synthesis and development of testosterone for clinical use. 61
30959485 2019
587
Mutation profile of BBS genes in patients with Bardet-Biedl syndrome: an Italian study. 61
31196119 2019
588
Effect of treatment with testosterone on endothelial function in hypogonadal men: a systematic review and meta-analysis. 61
31235898 2019
589
[Prevalence of anabolic androgenic steroid use, its effect on the male pituitary-gonadal axis, and the possibility of reproductive rehabilitation]. 61
31271715 2019
590
Acute myeloid leukaemia presenting with diabetes insipidus. 61
31185522 2019
591
Prader- Willi syndrome: An uptodate on endocrine and metabolic complications. 61
31065942 2019
592
Testosterone levels in men with chronic migraine. 61
31281602 2019
593
Prospective evaluation of hypogonadism in male metastatic renal cell carcinoma patients treated with targeted therapies. 61
29774795 2019
594
Chronic tyrosine kinase inhibitor (TKI) use in metastatic renal cell carcinoma (mRCC): can this lead to the adverse effect of hypogonadism? 61
30995130 2019
595
Nonstop mutation in the Kisspeptin 1 receptor (KISS1R) gene causes normosmic congenital hypogonadotropic hypogonadism. 61
31073722 2019
596
Severe Fanconi Anemia phenotypes in Fancd2 depletion mice. 61
31078270 2019
597
Are hypothyroidism and hypogonadism clinically relevant in patients with malignant gliomas? A longitudinal trial in patients with glioma. 61
30712840 2019
598
A critical assessment of case reports describing absent uterus in subjects with oestrogen deficiency. 61
30820975 2019
599
A toddler with a novel LEPR mutation. 61
30778850 2019
600
Pituitary pathology in traumatic brain injury: a review. 61
30927184 2019
601
Clinical Characteristics and Postoperative Recovery of Hypopituitarism in Patients with Nonfunctional Pituitary Adenoma. 61
30880207 2019
602
Risk factors for hypogonadism in young men with erectile dysfunction. 61
30932936 2019
603
Trends in erectile dysfunction research from 2008 to 2018: a bibliometric analysis. 61
31235897 2019
604
Current stepwise recommendations for hypogonadism screening in erectile dysfunction are not cost-effective. 61
31243352 2019
605
Undiagnosed prediabetes is highly prevalent in primary infertile men - results from a cross-sectional study. 61
30328251 2019
606
A rare case in literature: Isochromosome Xq in Klinefelter syndrome. 61
30746732 2019
607
Indications and outcomes of varicocele repair. 61
30990285 2019
608
Re: Trends in Testosterone Prescribing for Age-Related Hypogonadism in Men with and without Heart Disease. 61
30888894 2019
609
An analysis of online content related to testosterone supplementation. 61
29921150 2019
610
Improvements in semen parameters in men treated with clomiphene citrate-A retrospective analysis. 61
30779195 2019
611
[A four-generation pedigree affected with X-linked adrenal hypoplasia congenita due to a novel missense DAX1 mutation]. 61
31030432 2019
612
The association between body mass index and testosterone deficiency in aging Chinese men with benign prostatic hyperplasia: results from a cross-sectional study. 61
31058560 2019
613
Prostate Cancer, Gender Identity, and Testosterone Replacement Therapy in Klinefelter Syndrome: A Case Report and Literature Review. 61
31312556 2019
614
Screening for mutations in selected miRNA genes in hypogonadotropic hypogonadism patients. 61
30999277 2019
615
Testosterone replacement in congenital hypogonadotropic hypogonadism maintains bone density but has only limited osteoanabolic effects. 61
30851011 2019
616
Familial GATA6 mutation causing variably expressed diabetes mellitus and cardiac and renal abnormalities. 61
31051468 2019
617
Growth hormone deficiency and neurocognitive function in adult survivors of childhood acute lymphoblastic leukemia. 61
30690723 2019
618
Comparing the role of anti-Müllerian hormone as a marker of FSH action in male and female fertility. 61
30880521 2019
619
Clinical Translational Studies of Kisspeptin and Neurokinin B. 61
31869839 2019
620
Defective DNA Polymerase α-Primase Leads to X-Linked Intellectual Disability Associated with Severe Growth Retardation, Microcephaly, and Hypogonadism. 61
31006512 2019
621
Re: Clomiphene Citrate and Human Chorionic Gonadotropin are Both Effective in Restoring Testosterone in Hypogonadism: A Short-Course Randomized Study. 61
30747887 2019
622
Experimental hypogonadism: insulin resistance, biochemical changes and effect of testosterone substitution. 61
31054251 2019
623
A new compound heterozygous mutation in a female with 17α-hydroxylase/17,20-lyase deficiency, slipped capital femoral epiphysis, and adrenal myelolipoma. 61
30614301 2019
624
Endocrine implications of bariatric surgery: a review on the intersection between incretins, bone, and sex hormones. 61
31134746 2019
625
Luteinizing hormone signaling is involved in synchronization of Leydig cell's clock and is crucial for rhythm robustness of testosterone production†. 61
30722003 2019
626
Low testosterone is associated with frailty, muscle wasting and physical dysfunction among men receiving hemodialysis: a longitudinal analysis. 61
30085235 2019
627
Correlation of Olfactory Phenotype by Indian Smell Identification Test and Quantitative MRI of Olfactory Apparatus in Idiopathic Hypogonadotropic Hypogonadism. 61
31641641 2019
628
Adverse Health Outcomes in Relationship to Hypogonadism After Chemotherapy: A Multicenter Study of Testicular Cancer Survivors. 61
31085753 2019
629
Pathogenesis of Thalassemia Major-associated Osteoporosis: A Review with Insights from Clinical Experience 61
29991466 2019
630
Small cell lung cancer with panhypopituitarism due to ectopic adrenocorticotropic hormone syndrome: A case report. 61
31183350 2019
631
Clinical and genetic analysis in males with 46,XX disorders of sex development: A reproductive centre experience of 144 cases. 61
30623467 2019
632
Treatment of gonadotropin deficiency during the first year of life: long-term observation and outcome in five boys. 61
31067328 2019
633
Obesity and Hypogonadism-A Narrative Review Highlighting the Need for High-Quality Data in Adolescents. 61
31052376 2019
634
Enclomiphene citrate: A treatment that maintains fertility in men with secondary hypogonadism. 61
31063005 2019
635
Substance Abuse and Male Hypogonadism. 61
31121993 2019
636
Paediatric and adult-onset male hypogonadism. 61
31147556 2019
637
Paediatric and adult-onset male hypogonadism. 61
31147553 2019
638
Adverse events during testosterone replacement therapy in 95 young hypogonadal thalassemic men. 61
31125000 2019
639
High rates of ovarian function preservation after hematopoietic cell transplantation with melphalan-based reduced intensity conditioning for pediatric acute leukemia: an analysis from the Japan Association of Childhood Leukemia Study (JACLS). 61
30864117 2019
640
Metabolic Syndrome Is an Independent Risk Factor for Acquired Premature Ejaculation. 61
30588783 2019
641
Tribulus terrestris versus placebo in the treatment of erectile dysfunction and lower urinary tract symptoms in patients with late-onset hypogonadism: A placebo-controlled study. 61
30253697 2019
642
A New Case of PCSK1 Pathogenic Variant With Congenital Proprotein Convertase 1/3 Deficiency and Literature Review. 61
30383237 2019
643
Testosterone and Benign Prostatic Hyperplasia. 61
30803920 2019
644
How much does obesity affect the male reproductive function? 61
31391924 2019
645
Observational study of clinical outcomes for testosterone treatment of pubertal delay in Duchenne muscular dystrophy. 61
31023296 2019
646
Impact of pituitary dysfunction on cognitive and global outcome after traumatic brain injury and aneurysmal subarachnoid haemorrhage. 61
30761404 2019
647
The Health Threat Posed by the Hidden Epidemic of Anabolic Steroid Use and Body Image Disorders Among Young Men. 61
30239802 2019
648
Clinical Management of Congenital Hypogonadotropic Hypogonadism. 61
30698671 2019
649
Hyperprolactinemia associated with macroprolactinoma in a 17-year-old: A case report. 61
31016137 2019
650
Association of total and calculated free testosterone with androgen deficiency symptoms in patients with type 2 diabetes. 61
31000814 2019
651
The prevalence of low serum free testosterone and the short-term effect of anti-retroviral therapy in male Japanese treatment-naïve HIV patients. 61
30292767 2019
652
Increasing hypothalamic nucleobindin 2 levels and decreasing hypothalamic inflammation in obese male mice via diet and exercise alleviate obesity-associated hypogonadism. 61
30503692 2019
653
Testosterone Profiles After Brachytherapy for Localized Prostate Cancer. 61
30716344 2019
654
DIAGNOSIS OF ENDOCRINE DISEASE: Evaluation of bone fragility in endocrine disorders. 61
31042675 2019
655
Jaundice and anaemia as presenting features of an incomplete autoimmune polyglandular syndrome type II. 61
30962212 2019
656
Molecular diagnostics of disorders of sexual development: an Indian survey and systems biology perspective. 61
30550360 2019
657
Duplication of 10q24 locus: broadening the clinical and radiological spectrum. 61
30622331 2019
658
The ability of an LC-MS/MS-based erythrocyte GALT enzyme assay to predict the phenotype in subjects with GALT deficiency. 61
30718057 2019
659
An update on heart disease risk associated with testosterone boosting medications. 61
30998433 2019
660
Vitamin D, bone mineral density and risk of fracture in people with intellectual disabilities. 61
30569589 2019
661
Male infertility in renal failure and transplantation. 61
31080778 2019
662
Clomiphene Citrate for the Treatment of Hypogonadism. 61
30522888 2019
663
Re: Effects of Clomiphene Citrate on Male Obesity-Associated Hypogonadism: . 61
30759646 2019
664
Effects of liraglutide on obesity-associated functional hypogonadism in men. 61
30707677 2019
665
Primary amenorrhoea secondary to two different syndromes: a case study. 61
30878957 2019
666
Coexistence of Gonadal Dysgenesis and Mullerian Agenesis in a Female with 46 XX Karyotype: A Case Report. 61
31477946 2019
667
Physical activity counteracts metabolic syndrome-induced hypogonadotropic hypogonadism and erectile dysfunction in the rabbit. 61
30645174 2019
668
[Monitoring of the treatment of hypogonadotropic hypogonadism in the infant]. 61
29891229 2019
669
Osteoprotective Effects of Tribulus terrestris L.: Relationship Between Dehydroepiandrosterone Levels and Ca2+-Sparing Effect. 61
30888914 2019
670
Prevalence of Low Bone Density and Comorbid Hypogonadism in Patients With Chronic Pancreatitis. 61
30768576 2019
671
EXTREMELY LOW TESTOSTERONE DUE TO RELATIVE ENERGY DEFICIENCY IN SPORT: A CASE REPORT. 61
31967017 2019
672
Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model. 61
30833616 2019
673
Prospective Study on Sexual Dysfunction in Male Chinese Liver Transplant Recipients. 61
30836839 2019
674
Sexual Dysfunction in Men with Prediabetes. 61
30852183 2019
675
Clarifying the link between ibuprofen and hypogonadism. 61
30664744 2019
676
Xyosted--a testosterone auto-injector for hypogonadism. 61
30845097 2019
677
Management of Anabolic Steroid-Induced Infertility: Novel Strategies for Fertility Maintenance and Recovery. 61
30929329 2019
678
Cryptozoospermia after treatment with clomiphene citrate following long-term use of intramuscular testosterone undecanoate depot injection (Nebido®). 61
30870141 2019
679
Ablating astrocyte insulin receptors leads to delayed puberty and hypogonadism in mice. 61
30893295 2019
680
Pituitary-testicular Axis Dysfunction in Methimazole-induced Hypothyroidism in Rats. 61
30989148 2019
681
Kisspeptin and Prolactin. 61
31847029 2019
682
Sertoli Cell Function in Young Males with Metabolic Syndrome. 61
31161113 2019
683
AMH and INSL3 in testicular and extragonadal pathophysiology: what do we know? 61
30793542 2019
684
Successful in vitro maturation of oocytes in a woman with gonadotropin-resistant ovary syndrome associated with a novel combination of FSH receptor gene variants: a case report. 61
30610662 2019
685
Long-term testosterone therapy in type 2 diabetes is associated with reduced mortality without improvement in conventional cardiovascular risk factors. 61
30216622 2019
686
A 52-Week Study of Dose Adjusted Subcutaneous Testosterone Enanthate in Oil Self-Administered via Disposable Auto-Injector. 61
30296416 2019
687
Bone accrual in oligo-amenorrheic athletes, eumenorrheic athletes and non-athletes. 61
29758361 2019
688
Abaloparatide, a novel osteoanabolic PTHrP analog, increases cortical and trabecular bone mass and architecture in orchiectomized rats by increasing bone formation without increasing bone resorption. 61
30343166 2019
689
Bardet-Biedl syndrome: Antenatal presentation of forty-five fetuses with biallelic pathogenic variants in known Bardet-Biedl syndrome genes. 61
30614526 2019
690
Regulation of anti-Müllerian hormone (AMH) in males and the associations of serum AMH with the disorders of male fertility. 61
30381580 2019
691
Endocrine Manifestations in POEMS Syndrome: a case report and literature review. 61
30902082 2019
692
PROKR2 mutations in idiopathic hypogonadotropic hypogonadism: selective disruption of the binding to a Gα-protein leads to biased signaling. 61
30576231 2019
693
Klinefelter Syndrome: Clinical Spectrum Based on 44 Consecutive Cases from a South Indian Tertiary Care Center. 61
31161115 2019
694
Nivolumab-induced hypophysitis leading to hypopituitarism and secondary empty sella syndrome in a patient with non-small cell lung cancer. 61
30850565 2019
695
Gordon Holmes syndrome due to compound heterozygosity of two new PNPLA6 variants - A diagnostic challenge. 61
30555943 2019
696
Nonalcoholic Fatty Liver Disease, Male Sexual Dysfunction, and Infertility: Common Links, Common Problems. 61
30898592 2019
697
Vitamin D3 supplementation improves testicular function in diabetic rats through peroxisome proliferator-activated receptor-γ/transforming growth factor-beta 1/nuclear factor-kappa B. 61
29953732 2019
698
Differentiation of human induced pluripotent stem cells into Leydig-like cells with molecular compounds. 61
30833541 2019
699
Risk of Erythrocytosis During Concomitant Testosterone and SGLT2-Inhibitor Treatment: A Warning From Two Clinical Cases. 61
30395251 2019
700
DNA LIGASE IV SYNDROME: A RARE CAUSE OF GROWTH FAILURE & HYPOGONADISM. 61
31967023 2019
701
Trends in Testosterone Prescribing for Age-related Hypogonadism in Men With and Without Heart Disease. 61
30592484 2019
702
Cardiometabolic health in Turner syndrome. 61
30775849 2019
703
Sex hormone replacement therapy for individuals with Turner syndrome. 61
30809949 2019
704
Quality of life and chronic health conditions in childhood acute leukaemia survivors. 61
30017209 2019
705
[Implication in Paediatrics of the First International Consensus Statement for the Diagnosis and management of pseudohypoparathyroidism and related disorders]. 61
30591400 2019
706
Bifocal germinoma in a patient with 16p11.2 microdeletion syndrome. 61
30738016 2019
707
Rarity of Laurence Moon Bardet Biedl Syndrome and its Poor Management in the Pakistani Population. 61
31058008 2019
708
[Infertility Due to Hyperprolactinemia in Empty Sella : A Case Report]. 61
31067844 2019
709
Galactocele of adult male breast: A cytopathologist's perspective. 61
30461216 2019
710
High frequency of CHD7 mutations in congenital hypogonadotropic hypogonadism. 61
30733481 2019
711
The Optimal Indication for Testosterone Replacement Therapy in Late Onset Hypogonadism. 61
30736442 2019
712
An Internet-Based Survey to Assess Clinicians' Knowledge and Attitudes Towards Opioid-Induced Hypogonadism. 61
30269435 2019
713
Medical Treatments for Hypogonadism do not Significantly Increase the Risk of Deep Vein Thrombosis Over General Population Risk. 61
30447269 2019
714
Hormone Replacement Therapy and Opioid Tapering for Opioid-Induced Hypogonadism Among Patients with Chronic Noncancer Pain: A Systematic Review. 61
29727002 2019
715
Aggressiveness of Localized Prostate Cancer: the Key Value of Testosterone Deficiency Evaluated by Both Total and Bioavailable Testosterone: AndroCan Study Results. 61
30293206 2019
716
Sexual Identity Disorder and Psychosis in Klinefelter Syndrome: A Synthesis of Literature and a Case Report. 61
30672880 2019
717
Delayed hypopituitarism following Russell's viper envenomation: a case series and literature review. 61
30317419 2019
718
Glu2.53(90) of the GnRH receptor is part of the conserved G protein-coupled receptor structure and does not form a salt-bridge with Lys3.32(121). 61
30476558 2019
719
Role of Relative Malnutrition in Exercise Hypogonadal Male Condition. 61
30212398 2019
720
Dopamine agonist-responsive Cushing's disease. 61
30765454 2019
721
Exploring the spectrum of late effects following radical orchidectomy for stage I testicular seminoma: a systematic review of the literature. 61
30350189 2019
722
The My-T study: Patient satisfaction and preference comparing topical and nasal testosterone therapies. 61
30817284 2019
723
Can the positive association of osteocalcin with testosterone be unmasked when the preeminent hypothalamic-pituitary regulation of testosterone production is impaired? The model of spinal cord injury. 61
29729005 2019
724
Prevalence and associated phenotypes of PLXNA1 variants in normosmic and anosmic idiopathic hypogonadotropic hypogonadism. 61
30467832 2019
725
Thyroid function in patients with Prader-Willi syndrome: an Italian multicenter study of 339 patients. 61
30703060 2019
726
Implementation of a Pilot Pharmacist Testosterone Therapy Management Service. 61
30791810 2019
727
The protective effects of Crocin on testopathy in fat-fed and streptozotocin-treated diabetic rats: An experimental study. 61
31435592 2019
728
Use of medicinal doses of zinc as a safe and efficient coadjutant in the treatment of male hypogonadism. 61
30767598 2019
729
Endocrine complications of celiac disease: a case report and review of the literature. 61
30198791 2019
730
Endocrine aspects of Klinefelter syndrome. 61
30507702 2019
731
Endocrine and metabolic complications in children and adolescents with Sickle Cell Disease: an Italian cohort study. 61
30744584 2019
732
Osteogenesis Imperfecta Due to Combined Heterozygous Mutations in Both COL1A1 and COL1A2, Coexisting With Pituitary Stalk Interruption Syndrome. 61
30984112 2019
733
Correlation between serum P450arom and sex hormones in males with late-onset hypogonadism: a pilot study. 61
30657548 2019
734
Elevated Body Mass Index Is Associated with Secondary Hypogonadism Among Men Presenting to a Tertiary Academic Medical Center. 61
30350484 2019
735
The paradox of marrow adipose tissue in anorexia nervosa. 61
29458121 2019
736
Final Height and Endocrine Complications in Patients with β-Thalassemia Intermedia: Our Experience in Non-Transfused Versus Infrequently Transfused Patients and Correlations with Liver Iron Content. 61
31205630 2019
737
Selective Androgen Receptor Modulators: Current Knowledge and Clinical Applications. 61
30503797 2019
738
Remission of type 2 diabetes and pleiotropic effects of long-term testosterone treatment for "late-onset" hypogonadism: A case report. 61
30719309 2019
739
CYSTIC PROLACTINOMA: A SURGICAL DISEASE? 61
31967004 2019
740
Androgen Deficiency and Phosphodiesterase Type 5 Expression Changes in Aging Male: Therapeutic Implications. 61
31110491 2019
741
Werner's Syndrome: Understanding the Phenotype of Premature Aging-First Case Described in Colombia. 61
30891318 2019
742
A Follow-Up from Infancy to Puberty in a Japanese Male with SRY-Negative 46,XX Testicular Disorder of Sex Development Carrying a p.Arg92Trp Mutation in NR5A1. 61
30739115 2019
743
Sex hormones, obesity and type 2 diabetes: is there a link? 61
30533003 2019
744
Ginsenoside Rg3 protects mouse leydig cells against triptolide by downregulation of miR-26a. 61
31296984 2019
745
Gonadal failure among female patients after hematopoietic stem cell transplantation for non-malignant diseases. 61
31666763 2019
746
Dual-release hydrocortisone improves hepatic steatosis in patients with secondary adrenal insufficiency: a real-life study. 61
31489172 2019
747
Pituitary Involvement in Granulomatosis with Polyangiitis: A Retrospective Analysis in a Single Chinese Hospital and a Literature Review. 61
31781205 2019
748
[Relation between sexual dysfunction and metabolic syndrome]. 61
30640528 2019
749
Corrigendum: Hypogonadism and Sexual Dysfunction in Testicular Tumor Survivors: A Systematic Review. 61
31258516 2019
750
Investigating the basis of sexual dysfunction during late-onset hypogonadism. 61
30984376 2019
751
Obstructive Sleep Apnea and Testosterone Deficiency. 61
29774669 2019
752
Effects of CPAP on Testosterone Levels in Patients With Obstructive Sleep Apnea: A Meta-Analysis Study. 61
31496991 2019
753
Patients presenting to a Men's Health clinic are at higher risk for depression, insomnia, and sleep apnea. 61
30171191 2019
754
Glucose Abnormalities Associated to Prolactin Secreting Pituitary Adenomas. 61
31191454 2019
755
Are hypothyroidism and hypogonadism clinically relevant in patients with malignant gliomas? A longitudinal trial in patients with glioma. 61
30389240 2019
756
46 XX male syndrome with hypogonadotropic hypogonadism: A case report. 61
31650121 2019
757
Investigation of treatment for azoospermia due to male hypogonadotropic hypogonadism in Japan. 61
30302833 2019
758
Psychological Aspects of Congenital Hypogonadotropic Hypogonadism. 61
31333578 2019
759
Metabolic Disorders and Male Hypogonadotropic Hypogonadism. 61
31402895 2019
760
Long-Term Follow Up of the Erectile Function of Testicular Cancer Survivors. 61
31001201 2019
761
Growth in CHARGE syndrome: optimizing care with a multidisciplinary approach. 61
31534343 2019
762
Hormone Replacement Therapy in Cancer Survivors - Review of the Literature. 61
30617760 2019
763
Type 1 Diabetes Mellitus and Klinefelter Syndrome. 61
30146555 2019
764
Evidence for long noncoding RNA GAS5 up-regulationin patients with Klinefelter syndrome. 61
30612561 2019
765
Extensive Phenotyping for Potential Weight-Inducing Factors in an Outpatient Population with Obesity. 61
31216558 2019
766
Gonadotropin- and Adrenocorticotropic Hormone-Independent Precocious Puberty of Gonadal Origin in a Patient with Adrenal Hypoplasia Congenita Due to DAX1 Gene Mutation - A Case Report and Review of the Literature: Implications for the Pathomechanism. 61
30537713 2019
767
The Pulsatile Gonadorelin Pump Induces Earlier Spermatogenesis Than Cyclical Gonadotropin Therapy in Congenital Hypogonadotropic Hypogonadism Men. 61
30569789 2019
768
The severity of hypogonadism symptoms and its risk factors among male employees of Tehran University of Medical Sciences. 61
30651006 2019
769
Effect of Korean Herbal Formula (Modified Ojayeonjonghwan) on Androgen Receptor Expression in an Aging Rat Model of Late Onset Hypogonadism. 61
30584994 2019
770
Important lessons about testosterone therapy- weight loss vs. testosterone therapy for symptom resolution, classical vs. functional hypogonadism, and shortterm vs. lifelong testosterone therapy. 61
30651008 2019
771
Hypogonadism in Children with a Previous History of Cancer: Endocrine Management and Follow-Up. 61
30703774 2019
772
Re: Testosterone Therapy in Men with Hypogonadism: An Endocrine Society Clinical Practice Guideline. 61
30577344 2019
773
Age Induced Nitroso-Redox Imbalance Leads to Subclinical Hypogonadism in Male Mice. 61
30984111 2019
774
A study on hypogonadism in male HIV patients in northeastern part of India. 61
31143855 2019
775
Rutin ameliorates carbon tetrachloride (CCl4)-induced hepatorenal toxicity and hypogonadism in male rats. 61
31179192 2019
776
Late-Onset Hypogonadism as Primary Testicular Failure. 61
31244778 2019
777
Congenital Hypogonadotrophic Hypogonadism: Minipuberty and the Case for Neonatal Diagnosis. 61
30846970 2019
778
Type 2 Diabetes and Testosterone Therapy. 61
30079639 2019
779
Impact of Sleep Deprivation on the Hypothalamic-Pituitary-Gonadal Axis and Erectile Tissue. 61
30621925 2019
780
Nasal Placode Development, GnRH Neuronal Migration and Kallmann Syndrome. 61
31355196 2019
781
[Reproductive disorders and preservation of fertility in males with benign and malignant brain tumors]. 61
31166318 2019
782
Association of low testosterone with changes in non-cardiovascular biomarkers in adult men. 61
30670838 2019
783
Testosterone replacement therapy and the risk of adverse cardiovascular outcomes and mortality. 61
30976419 2019
784
A new genetic variant of hereditary apolipoprotein A-I amyloidosis: a case-report followed by discussion of diagnostic challenges and therapeutic options. 61
30665372 2019
785
Effects of Estradiol Therapy on Resting-State Functional Connectivity of Transgender Women After Gender-Affirming Related Gonadectomy. 61
31440128 2019
786
Opioid-mediated Sertoli cells apoptosis is involved in testicular homeostasis and/or reproductive dysfunction. 61
31023050 2019
787
[Venous thromboembolism and urological cancer: Epidemiology and therapeutically management]. 61
30316671 2019
788
Hypothalamic-Pituitary-Ovarian Axis Disorders Impacting Female Fertility. 61
30621143 2019
789
Gonadotropin replacement in male thalassemia major patients with arrested puberty and acquired hypogonadotropic hypogonadism (AAH): preliminary results and potential factors affecting induction of spermatogenesis. 61
30298384 2019
790
Whole Exome Sequencing Revealed a Novel Nonsense Variant in the GNRHR Gene Causing Normosmic Hypogonadotropic Hypogonadism in a Pakistani Family. 61
30947225 2019
791