Hypotrichosis Simplex disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

HHS MCID: HYP137 MIFTS: 35	Hypotrichosis Simplex (HHS) Categories: Rare diseases, Skin diseases
Genes Variations Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs Expand all tables

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Aliases & Classifications for Hypotrichosis Simplex

MalaCards integrated aliases for Hypotrichosis Simplex:

Name: Hypotrichosis Simplex ⁵² ⁵⁸ ⁷¹

Hereditary Hypotrichosis Simplex ⁵⁸ ³⁶ ⁶

Hhs ⁵²

Characteristics:

Orphanet epidemiological data:

⁵⁸

hypotrichosis simplex
Inheritance: Autosomal dominant,Autosomal recessive; Prevalence: <1/1000000 (Worldwide); Age of onset: Childhood; Age of death: normal life expectancy;

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Skin diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the skin and subcutaneous tissue

Disorders of skin appendages

Other nonscarring hair loss

Other specified nonscarring hair loss

Orphanet: ⁵⁸

Rare skin diseases

External Ids:

KEGG ³⁶ H00786

MESH via Orphanet ⁴⁴ C537160

ICD10 via Orphanet ³³ L65.8

UMLS via Orphanet ⁷² C1854310

Orphanet ⁵⁸ ORPHA55654

SNOMED-CT via HPO ⁶⁸ 278040002 56317004

UMLS ⁷¹ C1854310

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Summaries for Hypotrichosis Simplex

NIH Rare Diseases : ⁵² Hypotrichosis simplex is a rare form of hereditary hair loss without other abnormalities. Affected individuals typically show normal hair at birth, but experience hair loss and thinning of the hair shaft that starts during early childhood and progresses with age. Hypotrichosis simplex can be divided into 2 forms: the scalp-limited form and the generalized form , in which all body hair is affected. The progressive thinning of the hair shaft is a typical feature of androgenetic alopecia . Hypotrichosis simplex can be inherited either as an autosomal dominant or autosomal recessive trait . Some cases are caused by mutations in the APCDD1 gene on chromosome 18p11. To date, there is no treatment for this condition.

MalaCards based summary : Hypotrichosis Simplex, also known as hereditary hypotrichosis simplex, is related to hypotrichosis 3 and hypotrichosis 2. An important gene associated with Hypotrichosis Simplex is LIPH (Lipase H), and among its related pathways/superpathways are Regulation of FZD by ubiquitination and Wnt signaling network. The drugs Anti-Bacterial Agents and Gentamicins have been mentioned in the context of this disorder. Affiliated tissues include skin, and related phenotypes are alopecia and sparse body hair

KEGG : ³⁶ Hereditary hypotrichosis (HSS) is a rare autosomal dominant form of non-syndromic hair loss that affects men and women equally. It is characterized by progressing hair loss from childhood, culminating in an almost complete loss of scalp hair by the third decade.

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Related Diseases for Hypotrichosis Simplex

Diseases related to Hypotrichosis Simplex via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 200)

#	Related Disease	Score	Top Affiliating Genes
1	hypotrichosis 3	33.8	LPAR6 LIPH
2	hypotrichosis 2	33.5	LSS CDSN
3	hypotrichosis 8	31.8	LPAR6 LIPH DSG4 CDSN
4	hypotrichosis 11	29.9	SNRPE LPAR6 LIPH
5	familial woolly hair syndrome	29.7	LPAR6 LIPH DSG4 CDSN
6	hypotrichosis	27.0	WNT3A SNRPE RPL21 LSS LRP5 LPAR6
7	hypotrichosis simplex of the scalp	12.6
8	hypotrichosis 1	12.4
9	tumoral calcinosis, hyperphosphatemic, familial, 1	12.0
10	hemochromatosis, type 1	11.8
11	hypogonadotropic hypogonadism 7 with or without anosmia	11.8
12	dyskeratosis congenita, x-linked	11.8
13	heart-hand syndrome, slovenian type	11.7
14	hypogonadotropic hypogonadism	11.7
15	hypogonadotropic hypogonadism 15 with or without anosmia	11.4
16	hypothalamic hamartomas	11.3
17	marie unna congenital hypotrichosis	11.3
18	charge syndrome	11.3
19	dyskeratosis congenita, autosomal dominant 1	11.2
20	hypogonadotropic hypogonadism 2 with or without anosmia	11.2
21	dyskeratosis congenita, autosomal recessive 5	11.2
22	kallmann syndrome	11.2
23	hoyeraal hreidarsson syndrome	11.2
24	hyperinsulinemic hypoglycemia, familial, 6	11.2
25	hypogonadotropic hypogonadism 3 with or without anosmia	11.0
26	hypogonadotropic hypogonadism 4 with or without anosmia	11.0
27	hypogonadotropic hypogonadism 5 with or without anosmia	11.0
28	hypogonadotropic hypogonadism 6 with or without anosmia	11.0
29	hypogonadotropic hypogonadism 8 with or without anosmia	11.0
30	hypogonadotropic hypogonadism 9 with or without anosmia	11.0
31	hypogonadotropic hypogonadism 10 with or without anosmia	11.0
32	hypogonadotropic hypogonadism 11 with or without anosmia	11.0
33	hypogonadotropic hypogonadism 12 with or without anosmia	11.0
34	hypogonadotropic hypogonadism 13 with or without anosmia	11.0
35	hypogonadotropic hypogonadism 14 with or without anosmia	11.0
36	hypogonadotropic hypogonadism 16 with or without anosmia	11.0
37	hypogonadotropic hypogonadism 17 with or without anosmia	11.0
38	hypogonadotropic hypogonadism 18 with or without anosmia	11.0
39	hypogonadotropic hypogonadism 19 with or without anosmia	11.0
40	hypogonadotropic hypogonadism 20 with or without anosmia	11.0
41	hypogonadotropic hypogonadism 21 with or without anosmia	11.0
42	hypogonadotropic hypogonadism 22 with or without anosmia	11.0
43	bombay phenotype	11.0
44	tumoral calcinosis, hyperphosphatemic, familial, 2	11.0
45	tumoral calcinosis, hyperphosphatemic, familial, 3	11.0
46	human immunodeficiency virus type 1	10.5
47	alopecia	10.4
48	substance abuse	10.3
49	multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly	10.3
50	global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies	10.2

Graphical network of the top 20 diseases related to Hypotrichosis Simplex:

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Symptoms & Phenotypes for Hypotrichosis Simplex

Human phenotypes related to Hypotrichosis Simplex:

⁵⁸ ³¹ (show all 8)

#	Description	HPO Frequency	Orphanet Frequency	HPO Source Accession
1	alopecia ⁵⁸ ³¹	hallmark (90%)	Very frequent (99-80%)	HP:0001596
2	sparse body hair ⁵⁸ ³¹	hallmark (90%)	Very frequent (99-80%)	HP:0002231
3	sparse eyelashes ⁵⁸ ³¹	hallmark (90%)	Very frequent (99-80%)	HP:0000653
4	sparse scalp hair ³¹	hallmark (90%)		HP:0002209
5	sparse and thin eyebrow ³¹	hallmark (90%)		HP:0000535
6	sparse hair ⁵⁸		Frequent (79-30%)
7	sparse eyebrow ⁵⁸		Very frequent (99-80%)
8	hypotrichosis of the scalp ⁵⁸		Very frequent (99-80%)

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Drugs & Therapeutics for Hypotrichosis Simplex

Drugs for Hypotrichosis Simplex (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

#	Name	Status	Phase	Clinical Trials	Cas Number	PubChem Id
1	Anti-Bacterial Agents		Phase 2
2	Gentamicins		Phase 2
3	Anti-Infective Agents		Phase 2

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	The Efficacy of Topical Gentamycin for the Treatment of Hereditary Hypotrichosis Simplex Caused by Heterozygous Nonsense Mutations in CDSN Encoding Corneodesmosin	Unknown status	NCT03492866	Phase 2	Gentamicin Sulfate

Search NIH Clinical Center for Hypotrichosis Simplex

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Genetic Tests for Hypotrichosis Simplex

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Anatomical Context for Hypotrichosis Simplex

MalaCards organs/tissues related to Hypotrichosis Simplex:

⁴⁰

Skin

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Publications for Hypotrichosis Simplex

Articles related to Hypotrichosis Simplex:

(show top 50) (show all 62)

#	Title	Authors	PMID	Year
1	Mutations in SNRPE, which encodes a core protein of the spliceosome, cause autosomal-dominant hypotrichosis simplex. ⁶¹ ⁶	Pasternack SM...Betz RC	23246290	2013
2	A recurrent mutation in the APCDD1 gene responsible for hereditary hypotrichosis simplex in a large Chinese family. ⁶¹ ⁶	Li M...Yao Z	22512811	2012
3	Mutation in ribosomal protein L21 underlies hereditary hypotrichosis simplex. ⁶ ⁶¹	Zhou C...Zhang J	21412954	2011
4	A novel mutation in LPAR6 causes autosomal recessive hypotrichosis of the scalp. ⁶ ⁶¹	Nahum S...Sprecher E	21070332	2011
5	A new locus for hereditary hypotrichosis simplex maps to chromosome 13q12.12 approximately 12.3 in a Chinese family. ⁶¹ ⁶	Xu C...Song HD	19751230	2010
6	APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex. ⁶ ⁶¹	Shimomura Y...Christiano AM	20393562	2010
7	Novel mutations in G protein-coupled receptor gene (P2RY5) in families with autosomal recessive hypotrichosis (LAH3). ⁶ ⁶¹	Azeem Z...Ahmad W	18461368	2008
8	G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth. ⁶ ⁶¹	Pasternack SM...Betz RC	18297070	2008
9	An autosomal dominant form of hereditary hypotrichosis simplex maps to 18p11.32-p11.23 in an Italian family. ⁶¹ ⁶	Baumer A...Schinzel A	10878665	2000
10	Hereditary hypotrichosis simplex. ⁶ ⁶¹	Just M...Ferrandiz C	9621144	1998
11	Mutations in the LPAR6 and LIPH genes underlie autosomal recessive hypotrichosis/woolly hair in 17 consanguineous families from Pakistan. ⁶	Khan S...Ahmad W	21426374	2011
12	Mutations in the lipase H gene underlie autosomal recessive woolly hair/hypotrichosis. ⁶	Shimomura Y...Christiano AM	18830268	2009
13	The effect of inbreeding on the distribution of compound heterozygotes: a lesson from Lipase H mutations in autosomal recessive woolly hair/hypotrichosis. ⁶	Petukhova L...Christiano AM	19365138	2009
14	A novel deletion mutation in LIPH gene causes autosomal recessive hypotrichosis (LAH2). ⁶	Jelani M...Ahmad W	18445047	2008
15	Disruption of P2RY5, an orphan G protein-coupled receptor, underlies autosomal recessive woolly hair. ⁶	Shimomura Y...Christiano AM	18297072	2008
16	Localized autosomal recessive hypotrichosis due to a frameshift mutation in the desmoglein 4 gene exhibits extensive phenotypic variability within a Pakistani family. ⁶	Wajid M...Christiano AM	17392831	2007
17	A mutation in the lipase H (LIPH) gene underlie autosomal recessive hypotrichosis. ⁶	Ali G...Ahmad W	17333281	2007
18	Human hair growth deficiency is linked to a genetic defect in the phospholipase gene LIPH. ⁶	Kazantseva A...Rogaev EI	17095700	2006
19	Mutations in the desmoglein 4 gene are associated with monilethrix-like congenital hypotrichosis. ⁶	Shimomura Y...Ito M	16439973	2006
20	An autosomal recessive form of monilethrix is caused by mutations in DSG4: clinical overlap with localized autosomal recessive hypotrichosis. ⁶	Zlotogorski A...Pras E	16575393	2006
21	Mutations in the desmoglein 4 gene underlie localized autosomal recessive hypotrichosis with monilethrix hairs and congenital scalp erosions. ⁶	Schaffer JV...Christiano AM	16543896	2006
22	Desmoglein 4 in hair follicle differentiation and epidermal adhesion: evidence from inherited hypotrichosis and acquired pemphigus vulgaris. ⁶	Kljuic A...Christiano AM	12705872	2003
23	Mutations in the CDSN gene cause peeling skin disease and hypotrichosis simplex of the scalp. ⁶¹	van der Velden JJAJ...Steijlen PM	31663161	2020
24	Treatment of hereditary hypotrichosis simplex of the scalp with topical gentamicin. ⁶¹	Peled A...Sprecher E	31746457	2019
25	Biallelic pathogenic variants in the lanosterol synthase gene LSS involved in the cholesterol biosynthesis cause alopecia with intellectual disability, a rare recessive neuroectodermal syndrome. ⁶¹	Besnard T...Isidor B	30723320	2019
26	[Involvement of cholesterol metabolism in hypotrichosis simplex]. ⁶¹	Dereure O	30745120	2019
27	Autosomal-dominant hypotrichosis with woolly hair: Novel gene locus on chromosome 4q35.1-q35.2. ⁶¹	Schlaweck AE...Betz RC	31790498	2019
28	Bi-allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex. ⁶¹	Romano MT...Betz RC	30401459	2018
29	A novel insertion mutation of CDSN responsible for hypotrichosis simplex of scalp in a Chinese family. ⁶¹	Huang H...Zhang X	29797736	2018
30	Hereditary hypotrichosis simplex of the scalp. ⁶¹	Farah RS...Swick BL	28873114	2017
31	Hereditary hypotrichosis simplex of the scalp. ⁶¹	Moravvej-Farshi H...Hejazi S	25484430	2014
32	[Alopecia and hypotrichosis in childhood: clinical features and diagnosis]. ⁶¹	Betz RC	24898506	2014
33	Autosomal recessive transmission of a rare KRT74 variant causes hair and nail ectodermal dysplasia: allelism with dominant woolly hair/hypotrichosis. ⁶¹	Raykova D...Dahl N	24714551	2014
34	A novel nonsense mutation in the CDSN gene underlying hypotrichosis simplex of the scalp in a Chinese family. ⁶¹	Yang SX...Yang Y	23746069	2014
35	Homozygous missense mutation in the LIPH gene causing autosomal recessive hypotrichosis simplex in a Chinese patient. ⁶¹	Liu LH...Zhang XJ	24354445	2014
36	[Clinical investigation of a Chinese family with hypotrichosis simplex of the scalp and mutational analysis of CDSN gene]. ⁶¹	Huang XS...Quan QL	22875505	2012
37	'Black dots' seen under trichoscopy are not specific for alopecia areata. ⁶¹	Kowalska-Oledzka E...Rudnicka L	22681306	2012
38	Autosomal recessive hypotrichosis simplex with woolly hair: a report of a new family. ⁶¹	Al Aboud K...Al Aboud D	25386265	2011
39	Corneodesmosomes and corneodesmosin: from the stratum corneum cohesion to the pathophysiology of genodermatoses. ⁶¹	Jonca N...Serre G	21628128	2011
40	Mutations in two genes on chromosome 13 resulting in a complex hair and skin phenotype due to two rare genodermatoses: KLICK and autosomal recessive woolly hair/hypotrichosis simplex. ⁶¹	Horev L...Zlotogorski A	21275938	2011
41	A new amyloidosis caused by fibrillar aggregates of mutated corneodesmosin. ⁶¹	Caubet C...Serre G	20448140	2010
42	Marie Unna hereditary hypotrichosis caused by a novel mutation in the human hairless transcript. ⁶¹	Ramot Y...Zlotogorski A	20163456	2010
43	Loss of corneodesmosin leads to severe skin barrier defect, pruritus, and atopy: unraveling the peeling skin disease. ⁶¹	Oji V...Hennies HC	20691404	2010
44	In vitro analysis of LIPH mutations causing hypotrichosis simplex: evidence confirming the role of lipase H and lysophosphatidic acid in hair growth. ⁶¹	Pasternack SM...Betz RC	19536142	2009
45	Mutations in lipase H cause autosomal recessive hypotrichosis simplex with woolly hair. ⁶¹	Horev L...Zlotogorski A	19766349	2009
46	Novel mutations in the P2RY5 gene in one Turkish and two Indian patients presenting with hypotrichosis and woolly hair. ⁶¹	Pasternack SM...Betz RC	19529952	2009
47	Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction. ⁶¹	Leclerc EA...Guerrin M	19596793	2009
48	A large duplication in LIPH underlies autosomal recessive hypotrichosis simplex in four Middle Eastern families. ⁶¹	Nahum S...Sprecher E	18820939	2009
49	[Involvement of receptor P2Y5 and its ligand LPA in hypotrichosis simplex and autosomal recessive wooly hair syndrome]. ⁶¹	Dereure O	19061667	2008
50	Hypotrichosis simplex of the scalp. ⁶¹	Kanitakis J	17958879	2007

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Genes for Hypotrichosis Simplex

Genes related to Hypotrichosis Simplex (7 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	LIPH	Lipase H	Protein Coding	765.41	Pathogenic/Likely pathogenic ⁶ Causative germline mutation ⁵⁸ GeneCards inferred via : Publications Variants (show sections)	17333281 18830268 18445047 (more) 19365138 17095700 21426374
2	APCDD1	APC Down-Regulated 1	Protein Coding	366.38	Causative germline mutation ⁵⁸ GeneCards inferred via : Publications Summaries (show sections)
3	LPAR6	Lysophosphatidic Acid Receptor 6	Protein Coding	356.42	Causative germline mutation ⁵⁸ GeneCards inferred via : Publications (show sections)
4	LSS	Lanosterol Synthase	Protein Coding	356.42	Causative germline mutation ⁵⁸ GeneCards inferred via : Publications (show sections)
5	RPL21	Ribosomal Protein L21	Protein Coding	356.42	Causative germline mutation ⁵⁸ GeneCards inferred via : Publications (show sections)
6	SNRPE	Small Nuclear Ribonucleoprotein Polypeptide E	Protein Coding	356.42	Causative germline mutation ⁵⁸ GeneCards inferred via : Publications (show sections)
7	DSG4	Desmoglein 4	Protein Coding	350	Causative germline mutation ⁵⁸
8	CDSN	Corneodesmosin	Protein Coding	7.32	GeneCards inferred via : Publications (show sections)
9	LRP5	LDL Receptor Related Protein 5	Protein Coding	6.42	GeneCards inferred via : Publications (show sections)
10	WNT3A	Wnt Family Member 3A	Protein Coding	6.42	GeneCards inferred via : Publications (show sections)

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Variations for Hypotrichosis Simplex

ClinVar genetic disease variations for Hypotrichosis Simplex:

⁶ ‎‎

#	Gene	Name	Type	Significance	ClinVarId	dbSNP ID	GRCh37 Pos	GRCh38 Pos
1	LIPH	NM_139248.3(LIPH):c.736T>A (p.Cys246Ser)	SNV	Pathogenic/Likely pathogenic	225403	rs201249971	3:185237080-185237080	3:185519292-185519292

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Expression for Hypotrichosis Simplex

Search GEO for disease gene expression data for Hypotrichosis Simplex.

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Pathways for Hypotrichosis Simplex

Pathways related to Hypotrichosis Simplex according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Regulation of FZD by ubiquitination ⁶⁵ Show member pathways RNF mutants show enhanced WNT signaling and proliferation ⁶⁵	10.65	WNT3A LRP5
2	Wnt signaling network ¹	10.4	WNT3A LRP5
3	Negative regulation of TCF-dependent signaling by WNT ligand antagonists ⁶⁵ Show member pathways Misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling ⁶⁵	9.95	WNT3A LRP5

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GO Terms for Hypotrichosis Simplex

Cellular components related to Hypotrichosis Simplex according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cornified envelope	GO:0001533	9.16	DSG4 CDSN
2	desmosome	GO:0030057	8.96	DSG4 CDSN
3	Wnt-Frizzled-LRP5/6 complex	GO:1990851	8.62	WNT3A LRP5

Biological processes related to Hypotrichosis Simplex according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	canonical Wnt signaling pathway	GO:0060070	9.26	WNT3A LRP5
2	keratinocyte differentiation	GO:0030216	9.16	DSG4 CDSN
3	hair follicle development	GO:0001942	8.96	DSG4 APCDD1
4	Wnt signaling pathway	GO:0016055	8.8	WNT3A LRP5 APCDD1

Molecular functions related to Hypotrichosis Simplex according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	Wnt-protein binding	GO:0017147	8.62	LRP5 APCDD1

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Sources for Hypotrichosis Simplex

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia

Hypotrichosis Simplex (HHS)

Aliases & Classifications for Hypotrichosis Simplex

MalaCards integrated aliases for Hypotrichosis Simplex:

Characteristics:

Orphanet epidemiological data:

Classifications:

External Ids:

Summaries for Hypotrichosis Simplex

Related Diseases for Hypotrichosis Simplex

Diseases related to Hypotrichosis Simplex via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Hypotrichosis Simplex:

Symptoms & Phenotypes for Hypotrichosis Simplex

Human phenotypes related to Hypotrichosis Simplex:

Drugs & Therapeutics for Hypotrichosis Simplex

Drugs for Hypotrichosis Simplex (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Genetic Tests for Hypotrichosis Simplex

Anatomical Context for Hypotrichosis Simplex

MalaCards organs/tissues related to Hypotrichosis Simplex:

Publications for Hypotrichosis Simplex

Articles related to Hypotrichosis Simplex:

Genes for Hypotrichosis Simplex

Genes related to Hypotrichosis Simplex (7 elite genes):

Variations for Hypotrichosis Simplex

ClinVar genetic disease variations for Hypotrichosis Simplex:

Expression for Hypotrichosis Simplex

Pathways for Hypotrichosis Simplex

Pathways related to Hypotrichosis Simplex according to GeneCards Suite gene sharing:

GO Terms for Hypotrichosis Simplex

Cellular components related to Hypotrichosis Simplex according to GeneCards Suite gene sharing:

Biological processes related to Hypotrichosis Simplex according to GeneCards Suite gene sharing:

Molecular functions related to Hypotrichosis Simplex according to GeneCards Suite gene sharing:

Sources for Hypotrichosis Simplex