MCID: ITR001
MIFTS: 20

Iatrogenic Botulism

Categories: Eye diseases, Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Iatrogenic Botulism

MalaCards integrated aliases for Iatrogenic Botulism:

Name: Iatrogenic Botulism 58
Inadvertent Botulism 58

Characteristics:

Orphanet epidemiological data:

58
iatrogenic botulism
Prevalence: <1/1000000 (Worldwide); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 58  
Rare neurological diseases
Rare eye diseases
Rare infectious diseases


Summaries for Iatrogenic Botulism

MalaCards based summary : Iatrogenic Botulism, also known as inadvertent botulism, is related to foodborne botulism and spasticity. Affiliated tissues include eye and colon, and related phenotypes are fatigue and cranial nerve paralysis

Related Diseases for Iatrogenic Botulism

Diseases related to Iatrogenic Botulism via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 foodborne botulism 10.5
2 spasticity 10.3
3 ptosis 10.2
4 cerebral palsy 10.2
5 dystonia 10.2
6 dysphagia 10.1
7 migraine with or without aura 1 10.0
8 corpus callosum, partial agenesis of, x-linked 10.0
9 focal dystonia 10.0
10 constipation 10.0
11 blepharospasm 10.0
12 dysautonomia 10.0

Graphical network of the top 20 diseases related to Iatrogenic Botulism:



Diseases related to Iatrogenic Botulism

Symptoms & Phenotypes for Iatrogenic Botulism

Human phenotypes related to Iatrogenic Botulism:

58 31 (show all 13)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 fatigue 58 31 hallmark (90%) Very frequent (99-80%) HP:0012378
2 cranial nerve paralysis 58 31 hallmark (90%) Very frequent (99-80%) HP:0006824
3 dysphagia 58 31 hallmark (90%) Very frequent (99-80%) HP:0002015
4 xerostomia 58 31 hallmark (90%) Very frequent (99-80%) HP:0000217
5 ptosis 58 31 hallmark (90%) Very frequent (99-80%) HP:0000508
6 cerebral palsy 58 31 hallmark (90%) Very frequent (99-80%) HP:0100021
7 diaphragmatic paralysis 58 31 hallmark (90%) Very frequent (99-80%) HP:0006597
8 orthostatic hypotension 58 31 hallmark (90%) Very frequent (99-80%) HP:0001278
9 mydriasis 58 31 hallmark (90%) Very frequent (99-80%) HP:0011499
10 dyspnea 58 31 frequent (33%) Frequent (79-30%) HP:0002094
11 constipation 58 31 frequent (33%) Frequent (79-30%) HP:0002019
12 urinary retention 58 31 frequent (33%) Frequent (79-30%) HP:0000016
13 muscle weakness 58 Very frequent (99-80%)

Drugs & Therapeutics for Iatrogenic Botulism

Search Clinical Trials , NIH Clinical Center for Iatrogenic Botulism

Genetic Tests for Iatrogenic Botulism

Anatomical Context for Iatrogenic Botulism

MalaCards organs/tissues related to Iatrogenic Botulism:

40
Eye, Colon

Publications for Iatrogenic Botulism

Articles related to Iatrogenic Botulism:

(show all 21)
# Title Authors PMID Year
1
Repurposing of FDA-Approved Drugs for Treating Iatrogenic Botulism: A Paired 3D-QSAR/Docking Approach†. 61
31774239 2020
2
Lambert-Eaton Myasthenic Syndrome, Botulism, and Immune Checkpoint Inhibitor-Related Myasthenia Gravis. 61
31794471 2019
3
Cosmetic Injection of Botulinum Toxin Unmasking Subclinical Myasthenia Gravis: A Case Report and Literature Review. 61
31572161 2019
4
Electrophysiological abnormalities in iatrogenic botulism: Two case reports and review of the literature. 61
30348587 2019
5
Notes from the Field: Intestinal Colonization and Possible Iatrogenic Botulism in Mouse Bioassay-Negative Serum Specimens - Los Angeles County, California, November 2017. 61
30383741 2018
6
Iatrogenic Botulism Outbreak in Egypt due to a Counterfeit Botulinum Toxin A Preparation - A Descriptive Series of Patient Features and Outcome. 61
29786953 2018
7
Case of iatrogenic botulism after botulinotherapy in clinical practice. 61
30701823 2018
8
Tetanus, Botulism, and Diphtheria. 61
30273248 2018
9
Identification of Cross Reactive Antigens of C. botulinum Types A, B, E & F by Immunoproteomic Approach. 61
29332140 2018
10
Iatrogenic botulism after the therapeutic use of botulinum toxin-A: a case report and review of the literature. 61
22986799 2012
11
[Practice of botulism]. 61
21747147 2011
12
Iatrogenic botulism after botulinum toxin type A injections. 61
20150804 2010
13
Iatrogenic botulism in a child with spastic quadriparesis. 61
17940253 2007
14
Iatrogenic botulism due to therapeutic botulinum toxin a injection in a pediatric patient. 61
17909312 2007
15
Botulism in 4 adults following cosmetic injections with an unlicensed, highly concentrated botulinum preparation. 61
17119144 2006
16
Iatrogenic botulism in an amateur weight-lifter. 61
16639740 2006
17
Botulism: the challenge of diagnosis and treatment. 61
17224901 2006
18
Botulism. 61
16163636 2005
19
[Iatrogenic botulism: a complication to be taken into account in the treatment of child spasticity]. 61
14533094 2003
20
[Botulism disease]. 61
12170559 2002
21
Clinical spectrum of botulism. 61
9585323 1998

Variations for Iatrogenic Botulism

Expression for Iatrogenic Botulism

Search GEO for disease gene expression data for Iatrogenic Botulism.

Pathways for Iatrogenic Botulism

GO Terms for Iatrogenic Botulism

Sources for Iatrogenic Botulism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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