MCID: ICH023
MIFTS: 33

Ichthyosis, Acquired

Categories: Eye diseases, Fetal diseases, Genetic diseases, Rare diseases, Skin diseases

Aliases & Classifications for Ichthyosis, Acquired

MalaCards integrated aliases for Ichthyosis, Acquired:

Name: Ichthyosis, Acquired 54
Acquired Ichthyosis 54 60
Fish Scale Disease, Acquired 54
Ichthyosis Acquisita 54

Characteristics:

Orphanet epidemiological data:

60
acquired ichthyosis
Inheritance: Not applicable; Age of onset: Adult;

Classifications:

Orphanet: 60  
Rare skin diseases


Summaries for Ichthyosis, Acquired

MalaCards based summary : Ichthyosis, Acquired, also known as acquired ichthyosis, is related to ichthyosis vulgaris and ichthyosis. Affiliated tissues include skin, lung and thyroid, and related phenotypes are ichthyosis and pruritus

Related Diseases for Ichthyosis, Acquired

Diseases in the Ichthyosis family:

Ichthyosis, Congenital, Autosomal Recessive 2 Ichthyosis, Congenital, Autosomal Recessive 1
Ichthyosis, Congenital, Autosomal Recessive 4b Ichthyosis, Congenital, Autosomal Recessive 4a
Ichthyosis, Congenital, Autosomal Recessive 11 Ichthyosis, Congenital, Autosomal Recessive 5
Ichthyosis, Congenital, Autosomal Recessive 3 Ichthyosis, Congenital, Autosomal Recessive 6
Ichthyosis, Congenital, Autosomal Recessive 8 Ichthyosis, Congenital, Autosomal Recessive 7
Ichthyosis, Congenital, Autosomal Recessive 9 Ichthyosis, Congenital, Autosomal Recessive 10
Ichthyosis, Congenital, Autosomal Recessive 12 Ichthyosis, Congenital, Autosomal Recessive 14
Ichthyosis, Congenital, Autosomal Recessive 13 Autosomal Recessive Congenital Ichthyosis
Ichthyosis, Acquired

Diseases related to Ichthyosis, Acquired via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 61)
# Related Disease Score Top Affiliating Genes
1 ichthyosis vulgaris 11.4
2 ichthyosis 10.4
3 systemic lupus erythematosus 10.2
4 lymphoma 10.2
5 lupus erythematosus 10.2
6 mycosis fungoides 10.0
7 dermatomyositis 10.0
8 adenocarcinoma 10.0
9 suppression of tumorigenicity 12 10.0
10 graft-versus-host disease 9.9
11 anaplastic large cell lymphoma 9.9
12 hyperparathyroidism 9.9
13 thyroiditis 9.9
14 lymphomatoid papulosis 9.9
15 lymphomatous thyroiditis 9.9
16 pityriasis rotunda 9.9
17 breast cancer 9.8
18 hepatocellular carcinoma 9.8
19 renal cell carcinoma, nonpapillary 9.8
20 kaposi sarcoma 9.8
21 scleroderma, familial progressive 9.8
22 lung cancer 9.8
23 eosinophilic fasciitis 9.8
24 epidermodysplasia verruciformis 1 9.8
25 hemangiopericytoma, malignant 9.8
26 myeloma, multiple 9.8
27 reticulum cell sarcoma 9.8
28 bazex syndrome 9.8
29 psoriasis 7 9.8
30 leukemia, chronic myeloid 9.8
31 lung cancer susceptibility 3 9.8
32 psoriasis 11 9.8
33 factor v and factor viii, combined deficiency of, 2 9.8
34 psoriasis 13 9.8
35 myelodysplastic syndrome 9.8
36 autoimmune lymphoproliferative syndrome, type v 9.8
37 alopecia 9.8
38 diabetes mellitus 9.8
39 leukemia 9.8
40 peripheral t-cell lymphoma 9.8
41 renal tubular acidosis 9.8
42 anhidrosis 9.8
43 secondary hyperparathyroidism 9.8
44 leiomyosarcoma 9.8
45 transitional cell carcinoma 9.8
46 rhabdomyosarcoma 9.8
47 purpura 9.8
48 gastric adenocarcinoma 9.8
49 hypertrichosis 9.8
50 pyoderma 9.8

Graphical network of the top 20 diseases related to Ichthyosis, Acquired:



Diseases related to Ichthyosis, Acquired

Symptoms & Phenotypes for Ichthyosis, Acquired

Human phenotypes related to Ichthyosis, Acquired:

60 33 (show all 15)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 ichthyosis 60 33 hallmark (90%) Very frequent (99-80%) HP:0008064
2 pruritus 60 33 hallmark (90%) Very frequent (99-80%) HP:0000989
3 dry skin 60 33 hallmark (90%) Very frequent (99-80%) HP:0000958
4 palmoplantar keratoderma 60 33 frequent (33%) Frequent (79-30%) HP:0000982
5 erythema 60 33 frequent (33%) Frequent (79-30%) HP:0010783
6 papule 60 33 frequent (33%) Frequent (79-30%) HP:0200034
7 recurrent skin infections 60 33 frequent (33%) Frequent (79-30%) HP:0001581
8 immunologic hypersensitivity 60 33 frequent (33%) Frequent (79-30%) HP:0100326
9 renal insufficiency 60 33 occasional (7.5%) Occasional (29-5%) HP:0000083
10 autoimmunity 60 33 occasional (7.5%) Occasional (29-5%) HP:0002960
11 sarcoma 60 33 occasional (7.5%) Occasional (29-5%) HP:0100242
12 lymphoma 60 33 occasional (7.5%) Occasional (29-5%) HP:0002665
13 multiple myeloma 60 33 occasional (7.5%) Occasional (29-5%) HP:0006775
14 hyperkeratosis 60 Frequent (79-30%)
15 neoplasm 60 Occasional (29-5%)

Drugs & Therapeutics for Ichthyosis, Acquired

Search Clinical Trials , NIH Clinical Center for Ichthyosis, Acquired

Genetic Tests for Ichthyosis, Acquired

Anatomical Context for Ichthyosis, Acquired

MalaCards organs/tissues related to Ichthyosis, Acquired:

42
Skin, Lung, Thyroid, Breast, T Cells, Bone, Bone Marrow

Publications for Ichthyosis, Acquired

Articles related to Ichthyosis, Acquired:

(show top 50) (show all 85)
# Title Authors Year
1
Acquired ichthyosis as a paraneoplastic feature of ALK-negative anaplastic large cell lymphoma. ( 30407628 )
2019
2
Acquired ichthyosis associated with gastric adenocarcinoma. ( 29603207 )
2018
3
Acquired Ichthyosis. ( 30322306 )
2018
4
Nutritional Deficiency and Acquired Ichthyosis. ( 28470548 )
2017
5
Successful Treatment of Primary Cutaneous Peripheral T-Cell Lymphoma Presenting Acquired Ichthyosis with Oral Bexarotene Monotherapy. ( 28512419 )
2017
6
Ponatinib-induced ichthyosiform drug eruption: insights into acquired ichthyosis. ( 29469781 )
2017
7
Acquired ichthyosis during acitretin therapy for psoriasis vulgaris. ( 25175920 )
2016
8
Acquired ichthyosis and secondary hyperparathyroidism with systemic lupus erythematosus. ( 25297552 )
2015
9
Paraneoplastic acquired ichthyosis in lung cancer. ( 26143135 )
2015
10
Beware of underlying malignancy: acquired ichthyosis. ( 24355352 )
2014
11
Acquired ichthyosis associated with primary cutaneous CD30+ lymphoproliferative disorders. ( 24491290 )
2014
12
Acquired ichthyosis triggered by an osseous hemangiopericytoma: a case report and review of the literature. ( 24575005 )
2014
13
Kava dermopathy in Fiji: an acquired ichthyosis? ( 25069767 )
2014
14
A case of lymphomatoid papulosis with extensive limb disease followed by extracutaneous involvement and acquired ichthyosis. ( 22334164 )
2012
15
Acquired ichthyosis as a presenting finding of Hodgkin's lymphoma. ( 22983647 )
2012
16
Paraneoplastic Addisonian pigmentation and acquired ichthyosis as presenting features of multiple myeloma. ( 21276385 )
2011
17
Tumor lysis syndrome and acquired ichthyosis occurring after chemotherapy for lung adenocarcinoma. ( 22042943 )
2011
18
Acquired ichthyosis in a child with autoimmune thyroiditis. ( 20653873 )
2010
19
Granulomatous slack skin presenting as acquired ichthyosis and muscle masses. ( 19170408 )
2009
20
Acquired ichthyosis as the primary manifestation of renal cell carcinoma. ( 19432045 )
2009
21
Acquired ichthyosis as a paraneoplastic syndrome in Hodgkin's disease. ( 19661032 )
2009
22
Acquired ichthyosis associated with type 1 diabetes mellitus. ( 20046586 )
2009
23
Acquired ichthyosis with systemic lupus erythematosus: both dermatoses in a single skin biopsy specimen. ( 18441769 )
2008
24
Ichthyosiform mycosis fungoides: a neoplastic acquired ichthyosis. ( 17225024 )
2007
25
Acquired ichthyosis as a manifestation of acute cutaneous graft-versus-host disease. ( 17300650 )
2007
26
Acquired ichthyosis with pravastatin. ( 17373993 )
2007
27
Acquired ichthyosis disclosing non-Hodgkin's malignant lymphoma. ( 17409605 )
2007
28
Acquired ichthyosis associated with an overlap syndrome of systemic sclerosis and systemic lupus erythematosus. ( 16469086 )
2006
29
Myelodysplastic syndrome presenting as acquired ichthyosis. ( 16864016 )
2006
30
Acquired ichthyosis. ( 17010746 )
2006
31
Acquired ichthyosis and hypertrichosis due to autoimmune thyroiditis: therapeutic response to thyroxine replacement. ( 16190999 )
2005
32
Acquired ichthyosis associated with systemic lupus erythematosus. ( 15176664 )
2004
33
Granulomatous mycosis fungoides presenting as an acquired ichthyosis. ( 12653708 )
2003
34
Hereditary and acquired ichthyosis vulgaris. ( 12708996 )
2003
35
Histopathological and immunohistochemical assessment of acquired ichthyosis in patients with human T-cell lymphotropic virus type I-associated myelopathy. ( 14616369 )
2003
36
Acquired ichthyosis associated with dermatomyositis in a patient with hepatocellular carcinoma. ( 11251586 )
2001
37
Erythema gyratum repens and acquired ichthyosis associated with transitional cell carcinoma of the kidney. ( 11678878 )
2001
38
Anaplastic large-cell lymphoma associated with acquired ichthyosis. ( 10767704 )
2000
39
Acquired ichthyosis associated with chronic graft-versus-host disease following allogeneic peripheral blood stem cell transplantation in a patient with chronic myelogenous leukemia. ( 9645582 )
1998
40
Acquired ichthyosis, alopecia and loss of hair pigment associated with leiomyosarcoma. ( 9553915 )
1998
41
Dermatomyositis and acquired ichthyosis as paraneoplastic manifestations of ovarian tumor. ( 9329895 )
1997
42
Acquired ichthyosis associated with eosinophilic fasciitis. ( 8647977 )
1996
43
Mycosis fungoides presenting as an acquired ichthyosis. ( 8621821 )
1996
44
Acquired ichthyosis in bone marrow transplant recipients. ( 8682957 )
1996
45
Acrokeratosis paraneoplastica (Bazex syndrome) occurring with acquired ichthyosis in Hodgkin's disease. ( 7547410 )
1995
46
Lymphomatoid papulosis associated with acquired ichthyosis. ( 7909544 )
1994
47
Acquired ichthyosis as a manifestation of abdominal recurrence of non-Hodgkin's lymphoma. ( 8141127 )
1994
48
Acquired ichthyosis in concomitant HIV-1 and HTLV-II infection: a new association with intravenous drug abuse. ( 8227542 )
1993
49
Acquired ichthyosis and pityriasis rotunda. ( 8339196 )
1993
50
Acquired ichthyosis and pyoderma gangrenosum in a patient with systemic lupus erythematosus. ( 8348724 )
1993

Variations for Ichthyosis, Acquired

Expression for Ichthyosis, Acquired

Search GEO for disease gene expression data for Ichthyosis, Acquired.

Pathways for Ichthyosis, Acquired

GO Terms for Ichthyosis, Acquired

Sources for Ichthyosis, Acquired

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63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
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74 UMLS
75 UMLS via Orphanet
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