MCID: ICH023
MIFTS: 30

Ichthyosis, Acquired

Categories: Eye diseases, Fetal diseases, Genetic diseases, Rare diseases, Skin diseases

Aliases & Classifications for Ichthyosis, Acquired

MalaCards integrated aliases for Ichthyosis, Acquired:

Name: Ichthyosis, Acquired 52
Acquired Ichthyosis 52 58 32
Fish Scale Disease, Acquired 52
Ichthyosis Acquisita 52

Characteristics:

Orphanet epidemiological data:

58
acquired ichthyosis
Inheritance: Not applicable; Age of onset: Adult;

Classifications:

Orphanet: 58  
Rare skin diseases


Summaries for Ichthyosis, Acquired

NIH Rare Diseases : 52 The following summary is from Orphanet , a European reference portal for information on rare diseases and orphan drugs. Orpha Number: 454 Definition A rare epidermal disease characterized by rough, dry skin with prominent, plate-like scaling. It is non-hereditary and usually arises during adulthood in the context of a variety of diseases or conditions, like various types of cancer , autoimmune diseases , endocrine disorders , nutritional deficiencies, but also as a side effect of certain medications. Severity depends on the underlying disease or condition. Visit the Orphanet disease page for more resources.

MalaCards based summary : Ichthyosis, Acquired, also known as acquired ichthyosis, is related to ichthyosis vulgaris and ichthyosis. Affiliated tissues include skin, t cells and breast, and related phenotypes are ichthyosis and pruritus

Related Diseases for Ichthyosis, Acquired

Diseases in the Ichthyosis family:

Ichthyosis, Congenital, Autosomal Recessive 2 Ichthyosis, Congenital, Autosomal Recessive 1
Ichthyosis, Congenital, Autosomal Recessive 4b Ichthyosis, Congenital, Autosomal Recessive 4a
Ichthyosis, Congenital, Autosomal Recessive 11 Ichthyosis, Congenital, Autosomal Recessive 5
Ichthyosis, Congenital, Autosomal Recessive 3 Ichthyosis, Congenital, Autosomal Recessive 6
Ichthyosis, Congenital, Autosomal Recessive 8 Ichthyosis, Congenital, Autosomal Recessive 7
Ichthyosis, Congenital, Autosomal Recessive 9 Ichthyosis, Congenital, Autosomal Recessive 10
Ichthyosis, Congenital, Autosomal Recessive 12 Ichthyosis, Congenital, Autosomal Recessive 14
Ichthyosis, Congenital, Autosomal Recessive 13 Autosomal Recessive Congenital Ichthyosis
Ichthyosis, Acquired Inherited Ichthyosis
Autosomal Ichthyosis Syndrome

Diseases related to Ichthyosis, Acquired via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 98)
# Related Disease Score Top Affiliating Genes
1 ichthyosis vulgaris 11.6
2 ichthyosis 10.5
3 systemic lupus erythematosus 10.3
4 lupus erythematosus 10.3
5 keratosis 10.2
6 lymphoma 10.2
7 kaposi sarcoma 10.2
8 sarcoidosis 1 10.2
9 mycosis fungoides 10.2
10 dermatomyositis 10.2
11 anaplastic large cell lymphoma 10.1
12 sarcoma 10.1
13 spindle cell sarcoma 10.1
14 suppression of tumorigenicity 12 10.1
15 pityriasis rosea 10.1
16 autoimmune disease 10.1
17 graft-versus-host disease 10.1
18 hypothyroidism 10.1
19 adenocarcinoma 10.1
20 palmoplantar keratosis 10.1
21 acquired immunodeficiency syndrome 10.1
22 alopecia 10.1
23 lymphomatoid papulosis 10.1
24 breast cancer 10.0
25 hashimoto thyroiditis 10.0
26 dowling-degos disease 1 10.0
27 lymphoma, hodgkin, classic 10.0
28 immune deficiency disease 10.0
29 polycythemia vera 10.0
30 reticulum cell sarcoma 10.0
31 human immunodeficiency virus type 1 10.0
32 hyperparathyroidism 10.0
33 skin disease 10.0
34 connective tissue disease 10.0
35 thyroiditis 10.0
36 polycythemia 10.0
37 hodgkin's lymphoma, lymphocytic-histiocytic predominance 10.0
38 hepatocellular carcinoma 9.8
39 esophageal cancer 9.8
40 renal cell carcinoma, nonpapillary 9.8
41 scleroderma, familial progressive 9.8
42 lung cancer 9.8
43 eosinophilic fasciitis 9.8
44 epidermodysplasia verruciformis 1 9.8
45 hemangiopericytoma, malignant 9.8
46 hypoadrenocorticism, familial 9.8
47 hypoascorbemia 9.8
48 leprosy 3 9.8
49 myeloma, multiple 9.8
50 pituitary hormone deficiency, combined, 2 9.8

Graphical network of the top 20 diseases related to Ichthyosis, Acquired:



Diseases related to Ichthyosis, Acquired

Symptoms & Phenotypes for Ichthyosis, Acquired

Human phenotypes related to Ichthyosis, Acquired:

58 31 (show all 15)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 ichthyosis 58 31 hallmark (90%) Very frequent (99-80%) HP:0008064
2 pruritus 58 31 hallmark (90%) Very frequent (99-80%) HP:0000989
3 dry skin 58 31 hallmark (90%) Very frequent (99-80%) HP:0000958
4 palmoplantar keratoderma 58 31 frequent (33%) Frequent (79-30%) HP:0000982
5 erythema 58 31 frequent (33%) Frequent (79-30%) HP:0010783
6 papule 58 31 frequent (33%) Frequent (79-30%) HP:0200034
7 recurrent skin infections 58 31 frequent (33%) Frequent (79-30%) HP:0001581
8 immunologic hypersensitivity 58 31 frequent (33%) Frequent (79-30%) HP:0100326
9 renal insufficiency 58 31 occasional (7.5%) Occasional (29-5%) HP:0000083
10 autoimmunity 58 31 occasional (7.5%) Occasional (29-5%) HP:0002960
11 sarcoma 58 31 occasional (7.5%) Occasional (29-5%) HP:0100242
12 lymphoma 58 31 occasional (7.5%) Occasional (29-5%) HP:0002665
13 multiple myeloma 58 31 occasional (7.5%) Occasional (29-5%) HP:0006775
14 hyperkeratosis 58 Frequent (79-30%)
15 neoplasm 58 Occasional (29-5%)

Drugs & Therapeutics for Ichthyosis, Acquired

Search Clinical Trials , NIH Clinical Center for Ichthyosis, Acquired

Genetic Tests for Ichthyosis, Acquired

Anatomical Context for Ichthyosis, Acquired

MalaCards organs/tissues related to Ichthyosis, Acquired:

40
Skin, T Cells, Breast, Lung, Lymph Node, Thyroid, Bone Marrow

Publications for Ichthyosis, Acquired

Articles related to Ichthyosis, Acquired:

(show top 50) (show all 202)
# Title Authors PMID Year
1
Paraneoplastic eczematous eruption associated with Hodgkin's lymphoma. 61
31656430 2019
2
Lymphomatoid Papulosis Type B in a Patient with Crohn's Disease Treated with TNF-Alpha Inhibitors Infliximab and Adalimumab. 61
31542070 2019
3
[Paraneoplastic skin diseases]. 61
31273399 2019
4
Cutaneous paraneoplastic syndromes. 61
30736994 2019
5
Acquired Ichthyosis in the Setting of Active Pulmonary Tuberculosis. 61
31360287 2019
6
Acquired ichthyosis as a paraneoplastic feature of ALK-negative anaplastic large cell lymphoma. 61
30407628 2019
7
Acquired Ichthyosis. 61
30322306 2018
8
Acquired ichthyosis associated with gastric adenocarcinoma. 61
29603207 2018
9
Porphyria Cutanea Tarda Presenting with Scleroderma, Ichthyosis, Alopecia, and Vitiligo. 61
29928199 2018
10
Factors Affecting Dermatological Manifestations in Patients with End Stage Renal Disease. 61
29394966 2018
11
A Possible Case of Statin-Induced Ichthyosis in an Elderly Woman. 61
29383212 2018
12
Ponatinib-induced ichthyosiform drug eruption: insights into acquired ichthyosis. 61
29469781 2017
13
Nutritional Deficiency and Acquired Ichthyosis. 61
28470548 2017
14
Successful Treatment of Primary Cutaneous Peripheral T-Cell Lymphoma Presenting Acquired Ichthyosis with Oral Bexarotene Monotherapy. 61
28512419 2017
15
Cutaneous manifestations of breast cancer. 61
27178684 2016
16
[Eczematous lesions and acquired ichthyosis as a presenting finding of CD30+ anaplastic large cell lymphoma]. 61
25817852 2016
17
Acquired ichthyosis during acitretin therapy for psoriasis vulgaris. 61
25175920 2016
18
Paraneoplastic acquired ichthyosis in lung cancer. 61
26143135 2015
19
[Acquired ichthyosis revealing an Hodgkin's disease]. 61
25707575 2015
20
Acquired ichthyosis and secondary hyperparathyroidism with systemic lupus erythematosus. 61
25297552 2015
21
Kava dermopathy in Fiji: an acquired ichthyosis? 61
25069767 2014
22
Dermatosis as the initial presentation of gastric cancer: two cases. 61
25400431 2014
23
Beware of underlying malignancy: acquired ichthyosis. 61
24355352 2014
24
Acquired ichthyosis associated with primary cutaneous CD30+ lymphoproliferative disorders. 61
24491290 2014
25
Multiple paraneoplastic syndromes revealing non-small cell lung carcinoma. 61
25838865 2014
26
Acquired ichthyosis triggered by an osseous hemangiopericytoma: a case report and review of the literature. 61
24575005 2014
27
High prevalence of skin disorders among HTLV-1 infected individuals independent of clinical status. 61
24244779 2013
28
[Dermatomyositis and acute interstitial lung disease associated with MDA-5 antibodies: an atypical case]. 61
24090894 2013
29
The skin landscape in diabetes mellitus. Focus on dermocosmetic management. 61
23696712 2013
30
Type II reaction without erythema nodosum leprosum masquerading as lymphoma. 61
23614256 2012
31
Acquired ichthyosis as a presenting finding of Hodgkin's lymphoma. 61
22983647 2012
32
Hydroxyurea-induced dermatomyositis: true amyopathic dermatomyositis or dermatomyositis-like eruption? 61
22515579 2012
33
A case of lymphomatoid papulosis with extensive limb disease followed by extracutaneous involvement and acquired ichthyosis. 61
22334164 2012
34
[Acquired ichthyosis and livedoid palmoplantar keratoderma: two unusual skin manifestations of systemic lupus erythematosus]. 61
21429634 2012
35
[Acquired ichthyosis and haematological malignancies: five cases]. 61
22225737 2012
36
Tumor lysis syndrome and acquired ichthyosis occurring after chemotherapy for lung adenocarcinoma. 61
22042943 2011
37
Cutaneous paraneoplasia. 61
21855730 2011
38
Paraneoplastic Addisonian pigmentation and acquired ichthyosis as presenting features of multiple myeloma. 61
21276385 2011
39
Clinicopathologic characteristics of cutaneous chronic graft-versus-host diseases: a retrospective study in Korean patients. 61
21155089 2010
40
Cutaneous manifestations associated with HTLV-1 infection. 61
20883400 2010
41
Cutaneous manifestations of internal malignancies in a tertiary health care hospital of a developing country. 61
21152807 2010
42
Ichthyosiform sarcoidosis: A case report and review of the literature. 61
20804682 2010
43
Acquired ichthyosis in a child with autoimmune thyroiditis. 61
20653873 2010
44
Dermatosis as the Initial Manifestation of Malignant Breast Tumors: Retrospective Analysis of 4 Cases. 61
21049066 2010
45
Acquired ichthyosis as a paraneoplastic syndrome in Hodgkin's disease. 61
19661032 2009
46
Pityriasis rotunda. 61
19891922 2009
47
Juvenile folliculotropic and ichthyosiform mycosis fungoides. 61
19094122 2009
48
Ichthyosiform eruptions in association with primary cutaneous T-cell lymphomas. 61
19416265 2009
49
Myelopathy and adult T-cell leukemia associated with HTLV-1 in a young patient with hearing loss as the initial manifestation of disease. 61
19684985 2009
50
Acquired ichthyosis as the primary manifestation of renal cell carcinoma. 61
19432045 2009

Variations for Ichthyosis, Acquired

Expression for Ichthyosis, Acquired

Search GEO for disease gene expression data for Ichthyosis, Acquired.

Pathways for Ichthyosis, Acquired

GO Terms for Ichthyosis, Acquired

Sources for Ichthyosis, Acquired

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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