Aliases & Classifications for Ideomotor Apraxia

MalaCards integrated aliases for Ideomotor Apraxia:

Name: Ideomotor Apraxia 12 15
Apraxia, Ideomotor 76 44 73
Transcortical Apraxia 12
Limb-Kinetic Apraxia 12
Ideomotor Dyspraxia 12
Classic Apraxia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4627
MeSH 44 D020240
UMLS 73 C0234523

Summaries for Ideomotor Apraxia

MalaCards based summary : Ideomotor Apraxia, also known as apraxia, ideomotor, is related to apraxia and aphasia, and has symptoms including other symbolic dysfunction An important gene associated with Ideomotor Apraxia is CBS (Cystathionine-Beta-Synthase), and among its related pathways/superpathways are Chromatin Regulation / Acetylation and Neuroscience. Affiliated tissues include brain, parietal lobe and cortex, and related phenotypes are hematopoietic system and immune system

Wikipedia : 76 Ideomotor Apraxia, often IMA, is a neurological disorder characterized by the inability to correctly... more...

Related Diseases for Ideomotor Apraxia

Diseases related to Ideomotor Apraxia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 apraxia 33.2 GRN MAPT PSEN1
2 aphasia 31.1 GRN MAPT PSEN1
3 frontotemporal lobar degeneration with tdp43 inclusions, grn-related 31.0 GRN MAPT
4 supranuclear palsy, progressive, 1 30.1 CBS GRN MAPT PSEN1 TARDBP
5 dementia 29.4 BCHE FUS GRN MAPT PSEN1 TARDBP
6 alzheimer disease 29.4 BCHE GRN MAPT PSEN1 RTN4 TARDBP
7 agraphia 28.6 BCHE CBS DEDD GRN MAPT MBP
8 gerstmann syndrome 10.6 CBS CMKLR1
9 amyotrophic lateral sclerosis type 6 10.6 FUS TARDBP
10 alexia 10.5 MBP PSEN1 TARDBP
11 progressive non-fluent aphasia 10.5 GRN MAPT PSEN1
12 familial idiopathic basal ganglia calcification 10.5 MAPT PSEN1
13 behavioral variant of frontotemporal dementia 10.5 GRN MAPT PSEN1
14 alzheimer disease 2 10.5 BCHE MAPT PSEN1
15 gait apraxia 10.5 CBS GRN PSEN1
16 phonagnosia 10.5 GRN PSEN1 TARDBP
17 associative agnosia 10.5 GRN PSEN1 TARDBP
18 amyotrophic lateral sclerosis 18 10.5 FUS TARDBP
19 writing disorder 10.5 GRN PSEN1 TARDBP
20 lethal congenital contracture syndrome 1 10.5 FUS MBP TARDBP
21 expressive language disorder 10.4 FUS PSEN1 TARDBP
22 kluver-bucy syndrome 10.4 ATP2B3 MAPT NAGLU PSEN1
23 multiple cranial nerve palsy 10.4 ATP2B3 MBP MMP3
24 prosopagnosia 10.3 EP300 GRN PSEN1
25 echolalia 10.3 CBS GRN MAPT PSEN1
26 vascular dementia 10.3 BCHE MAPT MBP PSEN1
27 amyotrophic lateral sclerosis type 14 10.3 FUS TARDBP
28 extraosseous chondrosarcoma 10.3 EWSR1 FUS
29 semantic dementia 10.3 GRN MAPT PSEN1 TARDBP
30 auditory agnosia 10.2 EP300 MEG8
31 pedophilia 10.2 GRN RTN4
32 paraphilia disorder 10.2 CBS GRN RTN4
33 cerebritis 10.2
34 partial fetal alcohol syndrome 10.1 EP300 RTN4
35 finger agnosia 10.1 EP300 MBP MEG8
36 motor neuron disease 10.1 FUS GRN MAPT TARDBP
37 juxtacortical chondroma 10.1 EWSR1 FUS
38 hemiplegia 10.0
39 neuronitis 10.0
40 alien hand syndrome 10.0
41 marchiafava bignami disease 10.0
42 classic progressive supranuclear palsy syndrome 10.0
43 specific developmental disorder 10.0 GRN PSEN1 RTN4
44 myxoid chondrosarcoma 10.0 EWSR1 MAPT
45 frontotemporal dementia and/or amyotrophic lateral sclerosis 1 9.9 CBS FUS GRN PSEN1 TARDBP
46 pick disease of brain 9.9 FUS GRN MAPT PSEN1 TARDBP
47 postencephalitic parkinson disease 9.9 IVL MAPT TARDBP
48 frontotemporal dementia 9.8 FUS GRN MAPT PSEN1 TARDBP
49 dementia, lewy body 9.8 BCHE CBS GRN MAPT PSEN1 TARDBP
50 nominal aphasia 9.7 CBS FUS GRN MAPT PSEN1 TARDBP

Graphical network of the top 20 diseases related to Ideomotor Apraxia:



Diseases related to Ideomotor Apraxia

Symptoms & Phenotypes for Ideomotor Apraxia

UMLS symptoms related to Ideomotor Apraxia:


other symbolic dysfunction

MGI Mouse Phenotypes related to Ideomotor Apraxia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.9 EP300 GRN MAPT MBP MMP3 NAGLU
2 immune system MP:0005387 9.7 ELP1 EP300 GRN MAPT MBP MMP3
3 nervous system MP:0003631 9.36 ELP1 EP300 GRN MAPT MBP MMP3

Drugs & Therapeutics for Ideomotor Apraxia

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Electrical Polarization of the Brain in Corticobasal Syndrome Completed NCT00273897 Phase 2
2 Functional Rehabilitation of Upper Limb Apraxia in Patients Poststroke Unknown status NCT02199093 Not Applicable
3 EEG and EMG Analysis of Ideomotor Apraxia Completed NCT00024999
4 Using fMRI to Understand the Roles of Brain Areas for Fine Hand Movements Completed NCT00063115
5 Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks Recruiting NCT03153371

Search NIH Clinical Center for Ideomotor Apraxia

Cochrane evidence based reviews: apraxia, ideomotor

Genetic Tests for Ideomotor Apraxia

Anatomical Context for Ideomotor Apraxia

MalaCards organs/tissues related to Ideomotor Apraxia:

41
Brain, Parietal Lobe, Cortex, Testes

Publications for Ideomotor Apraxia

Articles related to Ideomotor Apraxia:

(show top 50) (show all 71)
# Title Authors Year
1
Unilateral Apraxic Agraphia without Ideomotor Apraxia from a callosal lesion in a patient with Marchiafava-Bignami disease. ( 29482459 )
2018
2
Callosal ideomotor apraxia in Alzheimer's disease. ( 27829324 )
2017
3
Motor Adaptation Deficits in Ideomotor Apraxia. ( 28205499 )
2017
4
Ideomotor Apraxia Due to Injury of the Superior Longitudinal Fasciculus: A Case Report. ( 27003199 )
2016
5
Dysfunction of the Human Mirror Neuron System in Ideomotor Apraxia: Evidence from Mu Suppression. ( 26942323 )
2016
6
Association of ideomotor apraxia with lesion site, etiology, neglect, and functional independence in patients with first ever stroke. ( 25936541 )
2015
7
Crossover learning of gestures in two ideomotor apraxia patients: A single case experimental design study. ( 26610072 )
2015
8
Response interference between functional and structural object-related actions is increased in patients with ideomotor apraxia. ( 22515637 )
2013
9
Inter- and intrahemispheric dissociations in ideomotor apraxia: a large-scale lesion-symptom mapping study in subacute brain-damaged patients. ( 22989580 )
2013
10
Ideomotor apraxia in agrammatic and logopenic variants of primary progressive aphasia. ( 23358624 )
2013
11
Teaching video neuroimages: callosal apraxia: a straightforward model of ideomotor apraxia. ( 23713093 )
2013
12
Tool-use and the left hemisphere: what is lost in ideomotor apraxia? ( 23262173 )
2013
13
Coordination deficits in ideomotor apraxia during visually targeted reaching reflect impaired visuomotor transformations. ( 20875439 )
2010
14
A new approach to rhythm cueing of cognitive functions: the case of ideomotor apraxia. ( 19673816 )
2009
15
Association of ideomotor apraxia with frontal gray matter volume loss in corticobasal syndrome. ( 19822784 )
2009
16
Effects of ideomotor apraxia on functional outcomes in patients with right hemiplegia. ( 18467934 )
2008
17
Cortico-cortical networks in patients with ideomotor apraxia as revealed by EEG coherence analysis. ( 18249498 )
2008
18
Ideomotor apraxia and functional ability. ( 17533759 )
2007
19
Ideomotor apraxia: a review. ( 17507030 )
2007
20
Impaired imitation of meaningless gestures in ideomotor apraxia: a conceptual problem not a disorder of action control? A single case investigation. ( 17306847 )
2007
21
Tapping, grasping and aiming in ideomotor apraxia. ( 16298401 )
2006
22
Evaluation of ideomotor apraxia in patients with stroke: a study of reliability and validity. ( 16546767 )
2006
23
Deficits in movement planning and intrinsic coordinate control in ideomotor apraxia. ( 17129191 )
2006
24
Goal-directed imitation in patients with Ideomotor Apraxia. ( 21038259 )
2005
25
Ecological implications of ideomotor apraxia: evidence from physical activities of daily living. ( 12578932 )
2003
26
Upper and lower face and ideomotor apraxia in patients with Alzheimer's disease. ( 12719633 )
2003
27
Cognitive representations of hand posture in ideomotor apraxia. ( 12667544 )
2003
28
Does the presence of ideomotor apraxia affect the prognosis of functional recovery in a woman who has had a stroke? ( 12211238 )
2002
29
Ideomotor apraxia in patients with Alzheimer disease: why do they use their body parts as objects? ( 11234908 )
2001
30
Ideomotor apraxia: a call to action. ( 11788737 )
2001
31
Cortical and subcortical contributions to ideomotor apraxia: analysis of task demands and error types. ( 11701604 )
2001
32
Critical dimensions affecting imitation performance of patients with ideomotor apraxia. ( 11804229 )
2001
33
Ideomotor apraxia, visuomotor control and the explicit representation of posture. ( 10775703 )
2000
34
Role of somatosensory feedback from tools in realizing movements by patients with ideomotor apraxia. ( 10023108 )
1999
35
Ideomotor apraxia in Alzheimer disease and left hemisphere stroke: limb transitive and intransitive movements. ( 10456799 )
1999
36
Ideomotor apraxia in progressive supranuclear palsy: a case study. ( 9918365 )
1999
37
Ideomotor apraxia test: a new test of imitation of gestures for elderly people. ( 10210892 )
1998
38
Ideomotor apraxia in early Alzheimer's disease: time and accuracy measures. ( 9853098 )
1998
39
Selective deficit of praxis imagery in ideomotor apraxia. ( 9270580 )
1997
40
Ideomotor apraxia: behavioral dimensions and neuroanatomical basis. ( 9184099 )
1997
41
Alien hand syndrome of the dominant hand and ideomotor apraxia of the nondominant hand. ( 8719649 )
1996
42
Ideomotor apraxia and cerebral dominance for motor control. ( 8713550 )
1996
43
Imitating gestures and manipulating a mannikin--the representation of the human body in ideomotor apraxia. ( 7731541 )
1995
44
Sensorimotor learning in ideomotor apraxia. ( 8684903 )
1995
45
Progressive ideomotor apraxia: evidence for a selective impairment of the action production system. ( 7772334 )
1995
46
Error types in ideomotor apraxia: a qualitative analysis. ( 7917246 )
1994
47
Motor performance in aphasia and ideomotor apraxia. ( 7532853 )
1994
48
Ideomotor apraxia in Alzheimer's disease. ( 8372621 )
1993
49
Ideomotor apraxia without aphasia and aphasia without apraxia: the anatomical support for a double dissociation. ( 7681472 )
1993
50
Neuropsychological and neuroanatomical dimensions of ideomotor apraxia. ( 1559165 )
1992

Variations for Ideomotor Apraxia

Expression for Ideomotor Apraxia

Search GEO for disease gene expression data for Ideomotor Apraxia.

Pathways for Ideomotor Apraxia

Pathways related to Ideomotor Apraxia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.86 ELP1 EP300 EWSR1 FUS
2 11.56 MAPT MBP PSEN1 RTN4 TARDBP
3
Show member pathways
10.95 MMP3 PSEN1 RTN4

GO Terms for Ideomotor Apraxia

Cellular components related to Ideomotor Apraxia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuronal cell body GO:0043025 9.02 FUS MAPT MBP PSEN1 RTN4

Biological processes related to Ideomotor Apraxia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of axonogenesis GO:0050771 9.26 PSEN1 RTN4
2 regulation of calcium-mediated signaling GO:0050848 9.16 CMKLR1 MAPT
3 internal protein amino acid acetylation GO:0006475 8.96 EP300 MAPT
4 astrocyte activation GO:0048143 8.62 MAPT PSEN1

Molecular functions related to Ideomotor Apraxia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.17 BCHE CBS EWSR1 FUS MAPT TARDBP
2 transcription coregulator activity GO:0003712 9.13 EP300 EWSR1 FUS
3 protein binding GO:0005515 10.09 ATP2B3 CBS CMKLR1 DEDD ELP1 EP300

Sources for Ideomotor Apraxia

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70 SNOMED-CT via Orphanet
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74 UMLS via Orphanet
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