MCID: IDM001
MIFTS: 36

Ideomotor Apraxia

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Ideomotor Apraxia

MalaCards integrated aliases for Ideomotor Apraxia:

Name: Ideomotor Apraxia 12 15 17
Apraxia, Ideomotor 77 45 74
Transcortical Apraxia 12
Limb-Kinetic Apraxia 12
Ideomotor Dyspraxia 12
Classic Apraxia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4627
MeSH 45 D020240
SNOMED-CT 69 39746003
UMLS 74 C0234523

Summaries for Ideomotor Apraxia

MalaCards based summary : Ideomotor Apraxia, also known as apraxia, ideomotor, is related to frontotemporal lobar degeneration with tdp43 inclusions, grn-related and supranuclear palsy, progressive, 1, and has symptoms including other symbolic dysfunction An important gene associated with Ideomotor Apraxia is RD3 (Retinal Degeneration 3, GUCY2D Regulator), and among its related pathways/superpathways is Neurotransmitter Clearance In The Synaptic Cleft. Affiliated tissues include brain, cortex and parietal lobe, and related phenotypes are hematopoietic system and immune system

Wikipedia : 77 Ideomotor Apraxia, often IMA, is a neurological disorder characterized by the inability to correctly... more...

Related Diseases for Ideomotor Apraxia

Diseases related to Ideomotor Apraxia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 61)
# Related Disease Score Top Affiliating Genes
1 frontotemporal lobar degeneration with tdp43 inclusions, grn-related 30.9 GRN MAPT
2 supranuclear palsy, progressive, 1 30.6 GRN MAPT SLC6A3
3 dementia 29.9 BCHE FUS GRN MAPT SLC6A3 TARDBP
4 agraphia 29.9 BCHE DEDD GRN MAPT MBP TARDBP
5 apraxia 11.9
6 alzheimer disease 10.6
7 aphasia 10.5
8 progressive non-fluent aphasia 10.4 GRN MAPT
9 behavioral variant of frontotemporal dementia 10.4 GRN MAPT
10 phonagnosia 10.4 GRN TARDBP
11 associative agnosia 10.4 GRN TARDBP
12 writing disorder 10.4 GRN TARDBP
13 prosopagnosia 10.4 EP300 GRN
14 akinetic mutism 10.3 MAPT SLC6A3
15 alexia 10.3 MBP TARDBP
16 echolalia 10.3 GRN MAPT
17 expressive language disorder 10.3 FUS TARDBP
18 mutism 10.3 GRN SLC6A3
19 panencephalitis, subacute sclerosing 10.3 MAPT MBP
20 kluver-bucy syndrome 10.3 ATP2B3 MAPT NAGLU
21 amyotrophic lateral sclerosis type 6 10.3 FUS TARDBP
22 vascular dementia 10.3 BCHE MAPT MBP
23 nominal aphasia 10.3 GRN MAPT TARDBP
24 semantic dementia 10.3 GRN MAPT TARDBP
25 amyotrophic lateral sclerosis 18 10.3 FUS TARDBP
26 myxoid chondrosarcoma 10.3 EWSR1 MAPT
27 cellular myxoid liposarcoma 10.3 EWSR1 FUS
28 amyotrophic lateral sclerosis type 14 10.3 FUS TARDBP
29 speech and communication disorders 10.2 GRN MAPT TARDBP
30 extraosseous chondrosarcoma 10.2 EWSR1 FUS
31 multiple system atrophy 1 10.2 MAPT MBP SLC6A3
32 parkinson disease, late-onset 10.2
33 juxtacortical chondroma 10.2 EWSR1 FUS
34 lethal congenital contracture syndrome 1 10.2 FUS MBP TARDBP
35 amyotrophic lateral sclerosis 21 10.2 FUS TARDBP
36 perry syndrome 10.2 GRN SLC6A3 TARDBP
37 specific developmental disorder 10.2 EP300 GRN SLC6A3
38 hemiplegia 10.2
39 dysgraphia 10.2
40 alien hand syndrome 10.2
41 corticobasal degeneration 10.2
42 marchiafava bignami disease 10.2
43 striatonigral degeneration 10.2 ATP2B3 SLC6A3
44 extraskeletal ewing sarcoma 10.1 EWSR1 FUS
45 auditory agnosia 10.1 EP300 MEG8
46 frontotemporal dementia and/or amyotrophic lateral sclerosis 1 10.1 FUS GRN MAPT TARDBP
47 frontotemporal dementia 10.1 FUS GRN MAPT TARDBP
48 amyotrophic lateral sclerosis 11 10.1 FUS TARDBP
49 postencephalitic parkinson disease 10.1 IVL MAPT TARDBP
50 motor neuron disease 10.1 FUS GRN MAPT TARDBP

Graphical network of the top 20 diseases related to Ideomotor Apraxia:



Diseases related to Ideomotor Apraxia

Symptoms & Phenotypes for Ideomotor Apraxia

UMLS symptoms related to Ideomotor Apraxia:


other symbolic dysfunction

MGI Mouse Phenotypes related to Ideomotor Apraxia:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10 CBSL CTBS DEDD EP300 GRN MAPT
2 immune system MP:0005387 9.9 CBSL CTBS DEDD EP300 GRN MAPT
3 nervous system MP:0003631 9.7 CBSL DEDD EP300 GRN MAPT MBP
4 vision/eye MP:0005391 9.17 CBSL EP300 GRN MAPT MBP NAGLU

Drugs & Therapeutics for Ideomotor Apraxia

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Electrical Polarization of the Brain in Corticobasal Syndrome Completed NCT00273897 Phase 2
2 EEG and EMG Analysis of Ideomotor Apraxia Completed NCT00024999
3 Using fMRI to Understand the Roles of Brain Areas for Fine Hand Movements Completed NCT00063115
4 Functional Rehabilitation of Upper Limb Apraxia in Patients Poststroke Completed NCT02199093 Not Applicable
5 Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks Recruiting NCT03153371

Search NIH Clinical Center for Ideomotor Apraxia

Cochrane evidence based reviews: apraxia, ideomotor

Genetic Tests for Ideomotor Apraxia

Anatomical Context for Ideomotor Apraxia

MalaCards organs/tissues related to Ideomotor Apraxia:

42
Brain, Cortex, Parietal Lobe, Testes

Publications for Ideomotor Apraxia

Articles related to Ideomotor Apraxia:

(show top 50) (show all 73)
# Title Authors Year
1
Unilateral Apraxic Agraphia without Ideomotor Apraxia from a callosal lesion in a patient with Marchiafava-Bignami disease. ( 29482459 )
2018
2
Callosal ideomotor apraxia in Alzheimer's disease. ( 27829324 )
2017
3
Motor Adaptation Deficits in Ideomotor Apraxia. ( 28205499 )
2017
4
Crossover learning of gestures in two ideomotor apraxia patients: A single case experimental design study. ( 26610072 )
2017
5
Ideomotor Apraxia Due to Injury of the Superior Longitudinal Fasciculus. ( 27003199 )
2016
6
Dysfunction of the Human Mirror Neuron System in Ideomotor Apraxia: Evidence from Mu Suppression. ( 26942323 )
2016
7
Association of ideomotor apraxia with lesion site, etiology, neglect, and functional independence in patients with first ever stroke. ( 25936541 )
2015
8
Tool-use and the left hemisphere: what is lost in ideomotor apraxia? ( 23262173 )
2013
9
Teaching video neuroimages: callosal apraxia: a straightforward model of ideomotor apraxia. ( 23713093 )
2013
10
Response interference between functional and structural object-related actions is increased in patients with ideomotor apraxia. ( 22515637 )
2013
11
Inter- and intrahemispheric dissociations in ideomotor apraxia: a large-scale lesion-symptom mapping study in subacute brain-damaged patients. ( 22989580 )
2013
12
Ideomotor apraxia in agrammatic and logopenic variants of primary progressive aphasia. ( 23358624 )
2013
13
Coordination deficits in ideomotor apraxia during visually targeted reaching reflect impaired visuomotor transformations. ( 20875439 )
2010
14
Association of ideomotor apraxia with frontal gray matter volume loss in corticobasal syndrome. ( 19822784 )
2009
15
A new approach to rhythm cueing of cognitive functions: the case of ideomotor apraxia. ( 19673816 )
2009
16
Cortico-cortical networks in patients with ideomotor apraxia as revealed by EEG coherence analysis. ( 18249498 )
2008
17
Effects of ideomotor apraxia on functional outcomes in patients with right hemiplegia. ( 18467934 )
2008
18
Impaired imitation of meaningless gestures in ideomotor apraxia: a conceptual problem not a disorder of action control? A single case investigation. ( 17306847 )
2007
19
Ideomotor apraxia: a review. ( 17507030 )
2007
20
Ideomotor apraxia and functional ability. ( 17533759 )
2007
21
Tapping, grasping and aiming in ideomotor apraxia. ( 16298401 )
2006
22
Evaluation of ideomotor apraxia in patients with stroke: a study of reliability and validity. ( 16546767 )
2006
23
Deficits in movement planning and intrinsic coordinate control in ideomotor apraxia. ( 17129191 )
2006
24
Goal-directed imitation in patients with Ideomotor Apraxia. ( 21038259 )
2005
25
Ecological implications of ideomotor apraxia: evidence from physical activities of daily living. ( 12578932 )
2003
26
Cognitive representations of hand posture in ideomotor apraxia. ( 12667544 )
2003
27
Upper and lower face and ideomotor apraxia in patients with Alzheimer's disease. ( 12719633 )
2003
28
Does the presence of ideomotor apraxia affect the prognosis of functional recovery in a woman who has had a stroke? ( 12211238 )
2002
29
Cortical and subcortical contributions to ideomotor apraxia: analysis of task demands and error types. ( 11701604 )
2001
30
Ideomotor apraxia: a call to action. ( 11788737 )
2001
31
Critical dimensions affecting imitation performance of patients with ideomotor apraxia. ( 11804229 )
2001
32
Ideomotor apraxia in patients with Alzheimer disease: why do they use their body parts as objects? ( 11234908 )
2001
33
Ideomotor apraxia, visuomotor control and the explicit representation of posture. ( 10775703 )
2000
34
Ideomotor apraxia in progressive supranuclear palsy: a case study. ( 9918365 )
1999
35
Role of somatosensory feedback from tools in realizing movements by patients with ideomotor apraxia. ( 10023108 )
1999
36
Ideomotor apraxia in Alzheimer disease and left hemisphere stroke: limb transitive and intransitive movements. ( 10456799 )
1999
37
Ideomotor apraxia in early Alzheimer's disease: time and accuracy measures. ( 9853098 )
1998
38
Ideomotor apraxia test: a new test of imitation of gestures for elderly people. ( 10210892 )
1998
39
Ideomotor apraxia: behavioral dimensions and neuroanatomical basis. ( 9184099 )
1997
40
Selective deficit of praxis imagery in ideomotor apraxia. ( 9270580 )
1997
41
Alien hand syndrome of the dominant hand and ideomotor apraxia of the nondominant hand. ( 8719649 )
1996
42
Ideomotor apraxia and cerebral dominance for motor control. ( 8713550 )
1996
43
Imitating gestures and manipulating a mannikin--the representation of the human body in ideomotor apraxia. ( 7731541 )
1995
44
Progressive ideomotor apraxia: evidence for a selective impairment of the action production system. ( 7772334 )
1995
45
Sensorimotor learning in ideomotor apraxia. ( 8684903 )
1995
46
Motor performance in aphasia and ideomotor apraxia. ( 7532853 )
1994
47
Error types in ideomotor apraxia: a qualitative analysis. ( 7917246 )
1994
48
Ideomotor apraxia without aphasia and aphasia without apraxia: the anatomical support for a double dissociation. ( 7681472 )
1993
49
Ideomotor apraxia in Alzheimer's disease. ( 8372621 )
1993
50
Neuropsychological and neuroanatomical dimensions of ideomotor apraxia. ( 1559165 )
1992

Variations for Ideomotor Apraxia

Expression for Ideomotor Apraxia

Search GEO for disease gene expression data for Ideomotor Apraxia.

Pathways for Ideomotor Apraxia

GO Terms for Ideomotor Apraxia

Biological processes related to Ideomotor Apraxia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 internal protein amino acid acetylation GO:0006475 8.62 EP300 MAPT

Molecular functions related to Ideomotor Apraxia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.1 BCHE EWSR1 FUS MAPT TARDBP YWHAQ

Sources for Ideomotor Apraxia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
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43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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