MCID: IDP068
MIFTS: 12

Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

Categories: Gastrointestinal diseases, Liver diseases, Metabolic diseases, Rare diseases

Aliases & Classifications for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

MalaCards integrated aliases for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects:

Name: Idiopathic Malabsorption Due to Bile Acid Synthesis Defects 59
Idiopathic Bile Acid Malabsorption 59

Classifications:



External Ids:

ICD10 via Orphanet 34 K90.8
Orphanet 59 ORPHA84065

Summaries for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

MalaCards based summary : Idiopathic Malabsorption Due to Bile Acid Synthesis Defects, also known as idiopathic bile acid malabsorption, is related to diarrhea and irritable bowel syndrome.

Related Diseases for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

Diseases related to Idiopathic Malabsorption Due to Bile Acid Synthesis Defects via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 diarrhea 10.5
2 irritable bowel syndrome 10.3
3 chylomicron retention disease 10.2
4 bile acid malabsorption, primary 10.2
5 gallbladder disease 1 10.0
6 inflammatory bowel disease 10.0
7 gastrointestinal system disease 10.0

Graphical network of the top 20 diseases related to Idiopathic Malabsorption Due to Bile Acid Synthesis Defects:



Diseases related to Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

Symptoms & Phenotypes for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

Drugs & Therapeutics for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase I, Double-Blind, Placebo-Controlled, Randomized, Parallel-Group Study to Evaluate the Safety and Efficacy of a Combination Herbal Therapy (CHT), Versus Placebo in Improving the Overall Quality of Life and Symptoms in Patients With Irritable Bowel Syndrome (IBS) Completed NCT00130741 Phase 1 CHT - herbal therapy

Search NIH Clinical Center for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

Genetic Tests for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

Anatomical Context for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

Publications for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

Articles related to Idiopathic Malabsorption Due to Bile Acid Synthesis Defects:

(show all 24)
# Title Authors PMID Year
1
Randomised clinical trial: colestyramine vs. hydroxypropyl cellulose in patients with functional chronic watery diarrhoea. 38
25858478 2015
2
Bile acid malabsorption investigated by selenium-75-homocholic acid taurine ((75)SeHCAT) scans: causes and treatment responses to cholestyramine in 298 patients with chronic watery diarrhoea. 38
22075299 2011
3
Managing bile acid diarrhoea. 38
21180614 2010
4
Defining primary bile acid diarrhea: making the diagnosis and recognizing the disorder. 38
20932141 2010
5
Bile acid malabsoption: a forgotten diagnosis? 38
20437979 2010
6
A new mechanism for bile acid diarrhea: defective feedback inhibition of bile acid biosynthesis. 38
19426836 2009
7
Chronic diarrhea caused by idiopathic bile acid malabsorption: an explanation at last. 38
19817666 2009
8
Systematic review: the prevalence of idiopathic bile acid malabsorption as diagnosed by SeHCAT scanning in patients with diarrhoea-predominant irritable bowel syndrome. 38
19570102 2009
9
Indirect evidence for increased mechanosensitivity of jejunal secretomotor neurones in patients with idiopathic bile acid malabsorption. 38
19432585 2009
10
Exploring possible mechanisms for primary bile acid malabsorption: evidence for different regulation of ileal bile acid transporter transcripts in chronic diarrhoea. 38
18403943 2008
11
Bile Acid malabsorption. 38
17298762 2007
12
Analysis of ileal sodium/bile acid cotransporter and related nuclear receptor genes in a family with multiple cases of idiopathic bile acid malabsorption. 38
17171805 2006
13
Accelerated regional bowel transit and overweight shown in idiopathic bile acid malabsorption. 38
15089906 2004
14
Absence of dysfunctional ileal sodium-bile acid cotransporter gene mutations in patients with adult-onset idiopathic bile acid malabsorption. 38
11589382 2001
15
Prognosis of adult-onset idiopathic bile acid malabsorption. 38
10440608 1999
16
Progress in idiopathic bile acid malabsorption. 38
9824594 1998
17
Biliary lipid composition in idiopathic bile acid malabsorption. 38
9824609 1998
18
Idiopathic bile acid malabsorption: qualitative and quantitative clinical features and response to cholestyramine. 38
9768525 1998
19
Postinfective diarrhoea and bile acid malabsorption. 38
9044199 1997
20
Idiopathic bile acid malabsorption: long-term outcome. 38
8590159 1995
21
Idiopathic bile acid malabsorption--a review of clinical presentation, diagnosis, and response to treatment. 38
1916479 1991
22
Primary bile acid diarrhoea without an ileal carrier defect: quantification of active bile acid transport across the ileal brush border membrane. 38
2040472 1991
23
[Causes and clinical diagnosis of chologenic diarrhea]. 38
2667263 1989
24
Diarrhoea associated with idiopathic bile acid malabsorption. Fact or fantasy? 38
4777749 1973

Variations for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

Expression for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

Search GEO for disease gene expression data for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects.

Pathways for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

GO Terms for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

Sources for Idiopathic Malabsorption Due to Bile Acid Synthesis Defects

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69 SNOMED-CT via HPO
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71 Tocris
72 UMLS
73 UMLS via Orphanet
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