ISCH
MCID: IDP022
MIFTS: 17

Idiopathic Spinal Cord Herniation (ISCH)

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Idiopathic Spinal Cord Herniation

MalaCards integrated aliases for Idiopathic Spinal Cord Herniation:

Name: Idiopathic Spinal Cord Herniation 52
Isch 52

Classifications:



Summaries for Idiopathic Spinal Cord Herniation

MalaCards based summary : Idiopathic Spinal Cord Herniation, also known as isch, is related to arachnoid cysts, intracranial and brown-sequard syndrome. The drug Tissue Plasminogen Activator has been mentioned in the context of this disorder. Affiliated tissues include spinal cord, heart and testes.

Related Diseases for Idiopathic Spinal Cord Herniation

Diseases related to Idiopathic Spinal Cord Herniation via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 24)
# Related Disease Score Top Affiliating Genes
1 arachnoid cysts, intracranial 10.5
2 brown-sequard syndrome 10.5
3 paraplegia 10.3
4 spastic paraparesis 10.3
5 spasticity 10.3
6 cerebrovascular disease 10.2
7 myeloid splenomegaly 10.2
8 splenomegaly 10.2
9 spondyloarthropathy 1 10.0
10 epidermoid cysts 10.0
11 spinal arachnoiditis 10.0
12 syringomyelia, noncommunicating isolated 10.0
13 spinal disease 10.0
14 inflammatory spondylopathy 10.0
15 arachnoiditis 10.0
16 neurilemmoma 10.0
17 syringomyelia 10.0
18 teratoma 10.0
19 radiculopathy 10.0
20 spondylitis 10.0
21 tarlov cysts 10.0
22 back pain 10.0
23 paresthesia 10.0
24 tremor 10.0

Graphical network of the top 20 diseases related to Idiopathic Spinal Cord Herniation:



Diseases related to Idiopathic Spinal Cord Herniation

Symptoms & Phenotypes for Idiopathic Spinal Cord Herniation

Drugs & Therapeutics for Idiopathic Spinal Cord Herniation

Drugs for Idiopathic Spinal Cord Herniation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Tissue Plasminogen Activator Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Multi-center, Rand., Double Blind, Sham Control, Parallel Arm Post Mech. Thrombectomy and/or rtPA Trial to Assess Safety and Effectiveness of the Ischemic Stroke System, as an Adjunct to Stand. of Care in Subjects With Acute Isch. Stroke Terminated NCT01874093 Phase 3
2 A NonRandomized, Multicenter, NonSig Risk Study With a NonInv, Passive PressureWave Method of Diagnosing Cerebral Anomalies to Develop a Diag. Algorithm for Cerebral Isch and to Test Sens./Spec. of This Algorithm in Determining Isch Stroke Terminated NCT01643525 Phase 2

Search NIH Clinical Center for Idiopathic Spinal Cord Herniation

Genetic Tests for Idiopathic Spinal Cord Herniation

Anatomical Context for Idiopathic Spinal Cord Herniation

MalaCards organs/tissues related to Idiopathic Spinal Cord Herniation:

40
Spinal Cord, Heart, Testes, Liver, Kidney, Bone, Brain

Publications for Idiopathic Spinal Cord Herniation

Articles related to Idiopathic Spinal Cord Herniation:

(show top 50) (show all 182)
# Title Authors PMID Year
1
Idiopathic Spinal Cord Herniation Associated With a Thoracic Disc Herniation: Case Report, Surgical Video, and Literature Review. 61
32101990 2020
2
Idiopathic spinal cord herniation. 61
32499121 2020
3
Transdural thoracic disc herniation with longitudinal slit-like dural defect causing intracranial hypotension. Report of two cases. 61
32439561 2020
4
Idiopathic Ventral Spinal Cord Herniation: Video Report and Systematic Review. 61
32376383 2020
5
HYPerspectral Enhanced Reality (HYPER): a physiology-based surgical guidance tool. 61
31309313 2020
6
Failure of Surgery in Idiopathic Spinal Cord Herniation: Case Report and Review of the Literature. 61
31449999 2020
7
Neuromuscular stimulation ameliorates ischemia-induced walking impairment in the rat claudication model. 61
31388976 2019
8
Protective effect of cyclosporine A in the treatment of severe hydronephrosis in a rabbit renal pelvic perfusion model 61
31652042 2019
9
Stronger correlation with myocardial ischemia of high-sensitivity troponin T than other biomarkers. 61
29380285 2019
10
Surgical Management of Idiopathic Thoracic Spinal Cord Herniation. 61
31158530 2019
11
Novel Strategy of Ventral Dural Repair for Idiopathic Thoracic Spinal Cord Herniation: Report of Outcomes and Review of Techniques. 61
30517700 2019
12
Zinc Supplementation and Ischemia Pre-conditioning in Renal Ischemia/Reperfusion Injury. 61
31496892 2019
13
Duplication of Ventral Dura as a Cause of Ventral Herniation of Spinal Cord-A Report of Two Cases and Review of the Literature. 61
30851464 2019
14
Thoracic idiopathic spinal cord herniation in a young patient: a diagnostic and therapeutic challenge. 61
31118170 2019
15
Operative Management of Idiopathic Spinal Cord Herniation: Case Series and Novel Technique for Repair of Recurrent Herniation. 61
30011010 2019
16
Painless local pressure application to test microvascular reactivity to ischemia. 61
30399363 2019
17
Clinico-radiological correlation and surgical outcome of idiopathic spinal cord herniation: A single centre retrospective case series. 61
30870118 2019
18
Expert's Comment concerning Grand Rounds case entitled "Idiopathic spinal cord herniation: consideration of its pathogenesis based on the histopathology of the dura mater'' by S. Shimizu et al. (Eur Spine J; 2017. DOI 10.1007/s00586-017-5147-y). 61
29675671 2019
19
Idiopathic spinal cord herniation: consideration of its pathogenesis based on the histopathology of the dura mater. 61
28593382 2019
20
Schwann Cell Precursors; Multipotent Glial Cells in Embryonic Nerves. 61
30971890 2019
21
Understanding Idiopathic Spinal Cord Herniation - A Comprehensive Review of Imaging and Literature. 61
31448173 2019
22
Factors Affecting the Severity of Neurological Disorders in Thoracic Idiopathic Spinal Cord Herniation. 61
30383724 2018
23
Letter to the Editor. Radiographic differentiation of idiopathic spinal cord herniation versus dorsal arachnoid webs. 61
29701570 2018
24
Ischemia-reperfusion injury alters skin microvascular responses to local heating of the index finger. 61
29438680 2018
25
Idiopathic thoracic spinal cord herniation. 61
29472069 2018
26
Disc herniation, occult on preoperative imaging but visualized microsurgically, as the cause of idiopathic thoracic spinal cord herniation. 61
29350292 2018
27
Spinal Cord Suspension Using Dentate Ligament Hitch Stitches: A Novel Technique for the Repair of Ventral Spinal Cord Herniation. 61
29462448 2018
28
Alpha linolenic acid decreases apoptosis and oxidized phospholipids in cardiomyocytes during ischemia/reperfusion. 61
28634855 2018
29
The effects of dexmedetomidine on biomarkers of oxidative stress and antioxidants in kidney. 61
30160154 2018
30
Reinforcement of the colon anastomosis with cyanoacrylate glue: a porcine model. 61
28595813 2017
31
Clinical and Radiographical Differences Between Thoracic Idiopathic Spinal Cord Herniation and Spinal Arachnoid Cyst. 61
27926670 2017
32
Idiopathic thoracic transdural intravertebral spinal cord herniation. 61
29021685 2017
33
Differentiation of idiopathic spinal cord herniation from dorsal arachnoid webs on MRI and CT myelography. 61
28338452 2017
34
Spinal cord herniation repair with microstaples: case report. 61
27813449 2017
35
[Coronary Artery Spasm during Anesthesia: Discussion of Cases Leading to Circulatory Collapse through 51 Reports of the Published Literature]. 61
30380291 2017
36
Idiopathic Spinal Cord Herniation: A Case Report. 61
27833524 2016
37
Surgical management of thoracic idiopathic spinal cord herniation. Technical case report and review. 61
27221089 2016
38
Visualization of NRAS RNA G-Quadruplex Structures in Cells with an Engineered Fluorogenic Hybridization Probe. 61
27508892 2016
39
Mystery Case: Brown-Séquard syndrome caused by idiopathic spinal cord herniation. 61
27462042 2016
40
Idiopathic spinal cord herniation of the cervical cord: unusual cause of proximal muscle weakness in upper limbs. 61
27190115 2016
41
The Efficacy of Hyperbaric Oxygen Therapy on Middle Cerebral Artery Occlusion in Animal Studies: A Meta-Analysis. 61
26859390 2016
42
History of diabetes mellitus is associated with elevated cardiac troponin I levels in patients with chest pain but no coronary heart disease. 61
26503081 2016
43
Optical Cryoimaging Reveals a Heterogeneous Distribution of Mitochondrial Redox State in ex vivo Guinea Pig Hearts and Its Alteration During Ischemia and Reperfusion. 61
27574574 2016
44
Assessing the intersection of cardiovascular disease, venous thromboembolism, and polycystic ovary syndrome. 61
26489726 2015
45
Acute hyperglycemia abolishes cardioprotection by remote ischemic perconditioning. 61
26581389 2015
46
Idiopathic Spinal Cord Herniation Presented as Brown-Sequard Syndrome : A Case Report and Surgical Outcome. 61
26539277 2015
47
Idiopathic spinal cord herniation: an imaging diagnosis with a significant delay. 61
25857588 2015
48
Spontaneous resolution of idiopathic thoracic spinal cord herniation: case report. 61
26023901 2015
49
Effect of morphine preconditioning in the delayed phase on the expression of p38 mitogen-activated protein kinase in a rabbit model of myocardial ischemia-reperfusion injury. 61
26125872 2015
50
Ankylosing spondylitis with idiopathic spinal cord herniation. 61
25463978 2015

Variations for Idiopathic Spinal Cord Herniation

Expression for Idiopathic Spinal Cord Herniation

Search GEO for disease gene expression data for Idiopathic Spinal Cord Herniation.

Pathways for Idiopathic Spinal Cord Herniation

GO Terms for Idiopathic Spinal Cord Herniation

Sources for Idiopathic Spinal Cord Herniation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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