ISCH
MCID: IDP022
MIFTS: 17

Idiopathic Spinal Cord Herniation (ISCH)

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Idiopathic Spinal Cord Herniation

MalaCards integrated aliases for Idiopathic Spinal Cord Herniation:

Name: Idiopathic Spinal Cord Herniation 52
Isch 52

Classifications:



Summaries for Idiopathic Spinal Cord Herniation

MalaCards based summary : Idiopathic Spinal Cord Herniation, also known as isch, is related to arachnoid cysts, intracranial and brown-sequard syndrome. The drug Tissue Plasminogen Activator has been mentioned in the context of this disorder. Affiliated tissues include spinal cord, heart and testes.

Related Diseases for Idiopathic Spinal Cord Herniation

Diseases related to Idiopathic Spinal Cord Herniation via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
# Related Disease Score Top Affiliating Genes
1 arachnoid cysts, intracranial 10.5
2 brown-sequard syndrome 10.5
3 paraplegia 10.3
4 spastic paraparesis 10.3
5 spasticity 10.3
6 cerebrovascular disease 10.2
7 myeloid splenomegaly 10.2
8 splenomegaly 10.2
9 back pain 10.2
10 spondyloarthropathy 1 10.0
11 epidermoid cysts 10.0
12 spinal arachnoiditis 10.0
13 syringomyelia, noncommunicating isolated 10.0
14 spinal disease 10.0
15 inflammatory spondylopathy 10.0
16 arachnoiditis 10.0
17 neurilemmoma 10.0
18 syringomyelia 10.0
19 teratoma 10.0
20 radiculopathy 10.0
21 spondylitis 10.0
22 tarlov cysts 10.0
23 paresthesia 10.0
24 tremor 10.0
25 rare surgical neurologic disease 10.0

Graphical network of the top 20 diseases related to Idiopathic Spinal Cord Herniation:



Diseases related to Idiopathic Spinal Cord Herniation

Symptoms & Phenotypes for Idiopathic Spinal Cord Herniation

Drugs & Therapeutics for Idiopathic Spinal Cord Herniation

Drugs for Idiopathic Spinal Cord Herniation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Tissue Plasminogen Activator Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Multi-center, Rand., Double Blind, Sham Control, Parallel Arm Post Mech. Thrombectomy and/or rtPA Trial to Assess Safety and Effectiveness of the Ischemic Stroke System, as an Adjunct to Stand. of Care in Subjects With Acute Isch. Stroke Terminated NCT01874093 Phase 3
2 A NonRandomized, Multicenter, NonSig Risk Study With a NonInv, Passive PressureWave Method of Diagnosing Cerebral Anomalies to Develop a Diag. Algorithm for Cerebral Isch and to Test Sens./Spec. of This Algorithm in Determining Isch Stroke Terminated NCT01643525 Phase 2

Search NIH Clinical Center for Idiopathic Spinal Cord Herniation

Genetic Tests for Idiopathic Spinal Cord Herniation

Anatomical Context for Idiopathic Spinal Cord Herniation

MalaCards organs/tissues related to Idiopathic Spinal Cord Herniation:

40
Spinal Cord, Heart, Testes, Liver, Kidney, Bone, Brain

Publications for Idiopathic Spinal Cord Herniation

Articles related to Idiopathic Spinal Cord Herniation:

(show top 50) (show all 178)
# Title Authors PMID Year
1
Neuromuscular stimulation ameliorates ischemia-induced walking impairment in the rat claudication model. 61
31388976 2019
2
Protective effect of cyclosporine A in the treatment of severe hydronephrosis in a rabbit renal pelvic perfusion model 61
31652042 2019
3
Stronger correlation with myocardial ischemia of high-sensitivity troponin T than other biomarkers. 61
29380285 2019
4
Surgical Management of Idiopathic Thoracic Spinal Cord Herniation. 61
31158530 2019
5
Failure of Surgery in Idiopathic Spinal Cord Herniation: Case Report and Review of the Literature. 61
31449999 2019
6
Novel Strategy of Ventral Dural Repair for Idiopathic Thoracic Spinal Cord Herniation: Report of Outcomes and Review of Techniques. 61
30517700 2019
7
Zinc Supplementation and Ischemia Pre-conditioning in Renal Ischemia/Reperfusion Injury. 61
31496892 2019
8
HYPerspectral Enhanced Reality (HYPER): a physiology-based surgical guidance tool. 61
31309313 2019
9
Duplication of Ventral Dura as a Cause of Ventral Herniation of Spinal Cord-A Report of Two Cases and Review of the Literature. 61
30851464 2019
10
Thoracic idiopathic spinal cord herniation in a young patient: a diagnostic and therapeutic challenge. 61
31118170 2019
11
Operative Management of Idiopathic Spinal Cord Herniation: Case Series and Novel Technique for Repair of Recurrent Herniation. 61
30011010 2019
12
Painless local pressure application to test microvascular reactivity to ischemia. 61
30399363 2019
13
Clinico-radiological correlation and surgical outcome of idiopathic spinal cord herniation: A single centre retrospective case series. 61
30870118 2019
14
Expert's Comment concerning Grand Rounds case entitled "Idiopathic spinal cord herniation: consideration of its pathogenesis based on the histopathology of the dura mater'' by S. Shimizu et al. (Eur Spine J; 2017. DOI 10.1007/s00586-017-5147-y). 61
29675671 2019
15
Idiopathic spinal cord herniation: consideration of its pathogenesis based on the histopathology of the dura mater. 61
28593382 2019
16
Schwann Cell Precursors; Multipotent Glial Cells in Embryonic Nerves. 61
30971890 2019
17
Understanding Idiopathic Spinal Cord Herniation - A Comprehensive Review of Imaging and Literature. 61
31448173 2019
18
Factors Affecting the Severity of Neurological Disorders in Thoracic Idiopathic Spinal Cord Herniation. 61
30383724 2018
19
Letter to the Editor. Radiographic differentiation of idiopathic spinal cord herniation versus dorsal arachnoid webs. 61
29701570 2018
20
Ischemia-reperfusion injury alters skin microvascular responses to local heating of the index finger. 61
29438680 2018
21
Idiopathic thoracic spinal cord herniation. 61
29472069 2018
22
Disc herniation, occult on preoperative imaging but visualized microsurgically, as the cause of idiopathic thoracic spinal cord herniation. 61
29350292 2018
23
Spinal Cord Suspension Using Dentate Ligament Hitch Stitches: A Novel Technique for the Repair of Ventral Spinal Cord Herniation. 61
29462448 2018
24
Alpha linolenic acid decreases apoptosis and oxidized phospholipids in cardiomyocytes during ischemia/reperfusion. 61
28634855 2018
25
The effects of dexmedetomidine on biomarkers of oxidative stress and antioxidants in kidney. 61
30160154 2018
26
Reinforcement of the colon anastomosis with cyanoacrylate glue: a porcine model. 61
28595813 2017
27
Clinical and Radiographical Differences Between Thoracic Idiopathic Spinal Cord Herniation and Spinal Arachnoid Cyst. 61
27926670 2017
28
Idiopathic thoracic transdural intravertebral spinal cord herniation. 61
29021685 2017
29
Differentiation of idiopathic spinal cord herniation from dorsal arachnoid webs on MRI and CT myelography. 61
28338452 2017
30
Spinal cord herniation repair with microstaples: case report. 61
27813449 2017
31
[Coronary Artery Spasm during Anesthesia: Discussion of Cases Leading to Circulatory Collapse through 51 Reports of the Published Literature]. 61
30380291 2017
32
Idiopathic Spinal Cord Herniation: A Case Report. 61
27833524 2016
33
Surgical management of thoracic idiopathic spinal cord herniation. Technical case report and review. 61
27221089 2016
34
Visualization of NRAS RNA G-Quadruplex Structures in Cells with an Engineered Fluorogenic Hybridization Probe. 61
27508892 2016
35
Mystery Case: Brown-Séquard syndrome caused by idiopathic spinal cord herniation. 61
27462042 2016
36
Idiopathic spinal cord herniation of the cervical cord: unusual cause of proximal muscle weakness in upper limbs. 61
27190115 2016
37
The Efficacy of Hyperbaric Oxygen Therapy on Middle Cerebral Artery Occlusion in Animal Studies: A Meta-Analysis. 61
26859390 2016
38
History of diabetes mellitus is associated with elevated cardiac troponin I levels in patients with chest pain but no coronary heart disease. 61
26503081 2016
39
Optical Cryoimaging Reveals a Heterogeneous Distribution of Mitochondrial Redox State in ex vivo Guinea Pig Hearts and Its Alteration During Ischemia and Reperfusion. 61
27574574 2016
40
Assessing the intersection of cardiovascular disease, venous thromboembolism, and polycystic ovary syndrome. 61
26489726 2015
41
Acute hyperglycemia abolishes cardioprotection by remote ischemic perconditioning. 61
26581389 2015
42
Idiopathic spinal cord herniation: an imaging diagnosis with a significant delay. 61
25857588 2015
43
Idiopathic Spinal Cord Herniation Presented as Brown-Sequard Syndrome : A Case Report and Surgical Outcome. 61
26539277 2015
44
Spontaneous resolution of idiopathic thoracic spinal cord herniation: case report. 61
26023901 2015
45
Effect of morphine preconditioning in the delayed phase on the expression of p38 mitogen-activated protein kinase in a rabbit model of myocardial ischemia-reperfusion injury. 61
26125872 2015
46
Ankylosing spondylitis with idiopathic spinal cord herniation. 61
25463978 2015
47
RNA-Seq identifies novel myocardial gene expression signatures of heart failure. 61
25528681 2015
48
Cromoglycate, not ketotifen, ameliorated the injured effect of warm ischemia/reperfusion in rat liver: role of mast cell degranulation, oxidative stress, proinflammatory cytokine, and inducible nitric oxide synthase. 61
26396497 2015
49
Role of nitric oxide in kidney and liver (as distance organ) function in bilateral renal ischemia-reperfusion: Effect of L-Arginine and NG-nitro-L-Arginine methyl ester. 61
26645018 2015
50
Baclofen facilitates sleep, neuroplasticity, and recovery after stroke in rats. 61
25493268 2014

Variations for Idiopathic Spinal Cord Herniation

Expression for Idiopathic Spinal Cord Herniation

Search GEO for disease gene expression data for Idiopathic Spinal Cord Herniation.

Pathways for Idiopathic Spinal Cord Herniation

GO Terms for Idiopathic Spinal Cord Herniation

Sources for Idiopathic Spinal Cord Herniation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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