Igg4-Related Disease disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: IGG007 MIFTS: 43	Igg4-Related Disease Categories: Rare diseases, Immune diseases, Genetic diseases
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Aliases & Classifications for Igg4-Related Disease

MalaCards integrated aliases for Igg4-Related Disease:

Name: Igg4-Related Disease ⁵³

Multifocal Fibrosclerosis ⁵³ ⁷³

Igg4-Positive Multiorgan Lymphoproliferative Syndrome ⁵³

Immunoglobulin G4-Related Sclerosing Disease ⁵³

Systemic Igg4-Related Plasmacytic Syndrome ⁵³

Systemic Igg4-Related Sclerosing Syndrome ⁵³

Igg4-Related Systemic Sclerosing Disease ⁵³

Multifocal Idiopathic Fibrosclerosis ⁵³

Retroperitoneal Fibrosis, Familial ⁵³

Igg4-Related Autoimmune Disease ⁵³

Igg4-Related Sclerosing Disease ⁵³

Mediastinal Fibrosis, Familial ⁵³

Igg4-Related Systemic Disease ⁵³

Igg4-Associated Disease ⁵³

Hyper-Igg4 Disease ⁵³

Igg4-Syndrome ⁵³

Classifications:

MalaCards categories:
Global: Rare diseases Genetic diseases
Anatomical: Immune diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the musculoskeletal system and connective tissue

Systemic connective tissue disorders

Other systemic involvement of connective tissue

Multifocal fibrosclerosis

External Ids:

ICD10 ³³ M35.5

UMLS ⁷³ C0494949

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Summaries for Igg4-Related Disease

NIH Rare Diseases : ⁵³ IgG4-related disease is an immune-mediated condition that can affect multiple organ systems. Common features include IgG4-related autoimmune pancreatitis, swelling of or within an organ system (an inflammatory pseudotumor), salivary gland disease (which can lead to enlargement of the salivary glands), swollen lymph nodes (lymphadenopathy), skin manifestations, and symptoms consistent with allergies or asthma. The cause of IgG4-related disease is unknown. Some researchers believe that it may be an autoimmune or allergic disorder. IgG4-related disease is usually treated with systemic steroids like prednisone. Immunosuppressive medications (azathioprine or mycophenolate mofetil) and biologics (rituximab or bortezomib) may be used in those who don't respond to steroids or for longer-term management. In severe cases, organ replacement therapy may be needed.

MalaCards based summary : Igg4-Related Disease, also known as multifocal fibrosclerosis, is related to autoimmune disease and idiopathic hypertrophic pachymeningitis. An important gene associated with Igg4-Related Disease is PDCD1 (Programmed Cell Death 1), and among its related pathways/superpathways are TRAF Pathway and Spinal Cord Injury. The drugs Prednisone and Prednisolone have been mentioned in the context of this disorder. Affiliated tissues include salivary gland, skin and lymph node, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : ⁷⁶ IgG4-related disease (IgG4-RD), formerly known as IgG4-related systemic disease, is a chronic... more...

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Related Diseases for Igg4-Related Disease

Diseases related to Igg4-Related Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 104)

#	Related Disease	Score	Top Affiliating Genes
1	autoimmune disease	27.4	PDCD1 TNFSF13 TNFSF13B
2	idiopathic hypertrophic pachymeningitis	11.3
3	igg4-related dacryoadenitis and sialadenitis	11.1
4	retroperitoneal fibrosis	10.1
5	pancreatitis	10.1
6	autoimmune pancreatitis	10.0
7	lymphoma	10.0
8	asthma	10.0
9	rosai-dorfman disease	10.0
10	castleman disease	9.9
11	prostatitis	9.9
12	aortitis	9.9
13	mediastinitis	9.9
14	wegener granulomatosis	9.8
15	membranous nephropathy	9.8
16	hepatitis	9.8
17	sialadenitis	9.8
18	interstitial nephritis	9.8
19	scleritis	9.8
20	purpura	9.8
21	thyroiditis	9.8
22	fibrosing mediastinitis	9.8
23	fibrosclerosis, multifocal	9.7
24	glomerulonephritis	9.7
25	multicentric castleman disease	9.7
26	sclerosing cholangitis	9.7
27	pericarditis	9.7
28	erdheim-chester disease	9.7
29	conjunctivitis	9.7
30	vasculitis	9.7
31	cholangitis	9.7
32	lipogranulomatosis	9.7
33	aneurysm	9.7
34	biliary cirrhosis, primary, 1	9.6
35	burkitt lymphoma	9.6
36	pulmonary hypertension, primary, 1	9.6
37	thrombocytopenic purpura, autoimmune	9.6
38	lung cancer	9.6
39	enterocolitis	9.6
40	autoimmune lymphoproliferative syndrome	9.6
41	aortic aneurysm, familial thoracic 1	9.6
42	autoimmune disease 1	9.6
43	alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity	9.6
44	cholangitis, primary sclerosing	9.6
45	psoriasis 14, pustular	9.6
46	cholangiocarcinoma	9.6
47	alopecia	9.6
48	autoimmune hepatitis	9.6
49	b-cell lymphomas	9.6
50	crohn's disease	9.6

Graphical network of the top 20 diseases related to Igg4-Related Disease:

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Symptoms & Phenotypes for Igg4-Related Disease

GenomeRNAi Phenotypes related to Igg4-Related Disease according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased shRNA abundance (Z-score > 2)	GR00366-A-115	9.28	PHB
2	Increased shRNA abundance (Z-score > 2)	GR00366-A-199	9.28	PHB
3	Increased shRNA abundance (Z-score > 2)	GR00366-A-214	9.28	PHB
4	Increased shRNA abundance (Z-score > 2)	GR00366-A-30	9.28	PDCD1
5	Increased shRNA abundance (Z-score > 2)	GR00366-A-36	9.28	PDCD1 PHB
6	Increased shRNA abundance (Z-score > 2)	GR00366-A-47	9.28	PDCD1
7	Increased shRNA abundance (Z-score > 2)	GR00366-A-57	9.28	PHB
8	Increased shRNA abundance (Z-score > 2)	GR00366-A-63	9.28	PDCD1

Sources

Drugs & Therapeutics for Igg4-Related Disease

Drugs for Igg4-Related Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 43)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Prednisone

Approved, Vet_approved

Phase 4,Phase 2,Phase 3

53-03-2

5865

Synonyms:

(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione

(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione

.delta. E

.delta.(sup1)-Cortisone

.delta.1-Cortisone

.delta.1-Dehydrocortisone

.delta.-Cortelan

.delta.-Cortisone

.delta.-Cortone

.delta.-E

.delta.sone

1,2-Dehydrocortisone

1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione

1,4-Pregnadiene-17a,21-diol-3,11,20-trione

1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione

1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione

1,4-Pregnadiene-17α,21-diol-3,11,20-trione

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione

17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione

1-Cortisone

1-Dehydrocortisone

53-03-2

68-59-7

81552_FLUKA

AC-11112

AC1L1LB2

AC1Q29EZ

Acis brand OF prednisone

ACon0_000082

ACon1_000297

Adasone

AI3-52939

Ancortone

apo-Prednisone

Apo-prednisone

Apo-Prednisone

Apotex brand OF prednisone

Aventis brand OF prednisone

Betapar

Bicortone

Bio-0649

BPBio1_000323

BRD-K85883481-001-04-2

BSPBio_000293

C07370

C21H26O5

Cartancyl

CCRIS 2646

CHEBI:8382

CHEMBL635

CID5865

Colisone

Cortan

Cortancyl

Cortidelt

Cotone

CPD001227202

Cutason

Dacorten

Dacortin

DB00635

Decortancyl

Decortin

Decortisyl

Dehydrocortisone

Dekortin

Delcortin

Dellacort

Dellacort A

delta cortelan

Delta Cortelan

Delta E

Delta E.

delta(sup 1)-Cortisone

delta(sup 1)-Dehydrocortisone

delta-1-Cortisone

delta-1-Dehydrocortisone

Delta-cortelan

Delta-Cortelan

Deltacortene

delta-Cortisone

Deltacortisone

Delta-cortisone

delta-Cortone

Deltacortone

Delta-cortone

Delta-dome

Delta-Dome

Deltasone

Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone

Deltison

Deltisona

Deltisone

Deltra

Diadreson

Di-Adreson

Diba brand OF prednisone

Econosone

EINECS 200-160-3

Encorton

Encortone

Enkortolon

Enkorton

Fawns and mcallan brand OF prednisone

Fernisone

Ferring brand OF prednisone

Fiasone

GALENpharma brand OF prednisone

Halsey drug brand OF prednisone

Hexal brand OF prednisone

HMS1568O15

HMS2090J13

Hoechst brand OF prednisone

Hostacortin

HSDB 3168

ICN brand OF prednisone

Incocortyl

In-Sone

Juvason

Kortancyl

Lichtenstein brand OF prednisone

Liquid pred

Liquid Pred

Lisacort

LMST02030180

Lodotra

LS-1325

MEGxm0_000443

Me-Korti

Merck brand OF prednisone

Merz brand OF prednisone

Metacortandracin

Meticorten

Meticorten (Veterinary)

Metrevet (Veterinary)

Mibe brand OF prednisone

MLS001061265

MLS001304073

MLS001335907

MLS001335908

MLS002154191

MLS002207083

MolPort-001-740-041

NCGC00090766-01

NCGC00090766-02

NCGC00090766-03

NCI60_000008

NCI-C04897

Nisona

Nizon

Novoprednisone

NSC 10023

NSC10023

Nurison

Orasone

Origen Prednisone

P1276

P6254_SIGMA

Panafcort

Panasol

Paracort

Parmenison

Pehacort

Pharmacia brand OF prednisone

PRD

Precort

Predeltin

Predni tablinen

Prednicen-M

Prednicorm

Prednicort

Prednicot

Prednidib

Prednilonga

Predniment

Prednison

Prednison acsis

Prednison galen

Prednison hexal

Prednisona

Prednisona [INN-Spanish]

Prednisone

Prednisone [INN:BAN]

Prednisone Intensol

Prednisonum

Prednisonum [INN-Latin]

Prednitone

Prednizon

Prednovister

Presone

Prestwick_405

Prestwick0_000077

Prestwick1_000077

Prestwick2_000077

Prestwick3_000077

Pronison

Pronisone

Rectodelt

Retrocortine

S1622_Selleck

SAM002264641

Schering-plough brand OF prednisone

Seatrace brand OF prednisone

Servisone

SK-Prednisone

SMR000718760

SMR001227202

Solvay brand OF prednisone

Sone

SPBio_002214

Sterapred

Supercortil

Trommsdorff brand OF prednisone

U 6020

Ultracorten

Ultracortene

UNII-VB0R961HZT

Winpred

WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ

Wojtab

Zenadrid

Zenadrid (veterinary)

Zenadrid [veterinary]

ZINC03875357

Prednisolone

Approved, Vet_approved

Phase 4,Phase 2

50-24-8

5755

Synonyms:

(11b)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione

(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione

(11β)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione

.DELTA.1-Cortisol

.DELTA.1-Dehydrocortisol

.DELTA.1-Dehydrohydrocortisone

.DELTA.1-Hydrocortisone

.delta.-Cortef

.delta.-Stab

1,2-Dehydrohydrocortisone

1,4-Pregnadiene-11b,17a,21-triol-3,20-dione

1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione

1,4-Pregnadiene-11β,17α,21-triol-3,20-dione

1,4-Pregnadiene-3,20-dione-11b,17a,21-triol

1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol

1,4-Pregnadiene-3,20-dione-11β,17α,21-triol

1-Dehydrocortisol

1-Dehydrohydrocortisone

3,20-dioxo-11b,17a,21-Trihydroxy-1,4-pregnadiene

3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene

3,20-dioxo-11β,17α,21-trihydroxy-1,4-pregnadiene

46656_FLUKA

46656_RIEDEL

50-24-8

58201-11-9

8056-11-9

AC-1773

AC1L1L2E

Ak-Pred

Ak-Tate

Alphadrol

Articulose-50

Bio-0666

BPBio1_000164

BRD-K98039984-001-03-0

BRN 1354103

BSPBio_000148

Bubbli-Pred

C07369

CCRIS 980

CHEBI:8378

CHEMBL131

CID5755

Codelcortone

Co-Hydeltra

CO-Hydeltra

component of Ataraxoid

component of K-Predne-Dome

Cordrol

Cortalone

Cotogesic

Cotolone

CPD000718761

D00472

D011239

DB00860

Decaprednil

Decortin H

Delcortol

Delta F

delta(1)-Cortisol

delta(1)-Dehydrocortisol

Delta(1)-Dehydrocortisol

delta(1)-Dehydrohydrocortisone

Delta(1)-dehydrohydrocortisone

Delta(1)-Dehydrohydrocortisone

delta(1)-Hydrocortisone

Delta(1)-Hydrocortisone

delta(sup 1)-Cortisol

delta(sup 1)-Dehydrocortisol

delta(sup 1)-Dehydrohydrocortisone

delta(sup 1)-Hydrocortisone

Delta-Cortef

Delta-Cortef (TN)

Deltacortenol

Deltacortril

Deltacortril Enteric

delta-dehydrocortisol

delta-dehydrohydrocortisone

Delta-Ef-Cortelan

delta-hydrocortisone

Deltahydrocortisone

Deltasolone

Delta-stab

Delta-Stab

Deltisilone

Depo-Medrol

Derpo Pd

Derpo PD

Dexa-Cortidelt hostacortin H

Dexa-Cortidelt Hostacortin H

Di adreson F

Di Adreson F

Di-adreson F

Di-Adreson F

Di-adreson-F

DiAdresonF

Di-Adreson-F

Dicortol

Donisolone

Dydeltrone

Eazolin D

Econopred

Econopred Plus

EINECS 200-021-7

Erbacort

Erbasona

Estilsona

Fernisolone

Fernisolone P

Fernisolone-P

Flamasone

HMS1568H10

HMS2090J05

Hostacortin H

HSDB 3385

Hydeltra

Hydeltrasol

Hydeltra-Tba

Hydeltrone

Hydrodeltalone

Hydrodeltisone

Hydroretrocortin

Hydroretrocortine

Inflamase Forte

Inflamase Mild

I-Pred

K 1557

Key-Pred

Klismacort

Lentosone

Lite Pred

LMST02030179

LS-7669

Medrol

Medrol Acetate

Metacortandralone

Methylprednisolone acetate

Methylprednisolone Acetate

Meticortelone

Meti-Derm

Metreton

MLS001304083

MLS002154250

MLS002207037

MolPort-002-507-147

M-Predrol

NCGC00179649-01

Neo-Delta-Cortef

Nisolone

Nor-Pred T.B.A.

NSC 9120

NSC9120

NSC9900

Ocu-Pred

Ocu-Pred Forte

Ophtho-Tate

Orapred

P0152_SIGMA

P0637

P6004_SIGMA

Panafcortelone

Paracortol

Paracotol

Pediapred

Poly-Pred

PRDL

Precortalon

Precortancyl

Precortilon

Precortisyl

Pred Forte

Pred Mild

Predair

Predair A

Predair Forte

Predalone 50

Predalone T.B.A.

Predate

Predate Tba

Predate-50

Predcor-25

Predcor-50

Predcor-Tba

PRED-G

Predisolone sodium phosphate

Predisolone Sodium Phosphate

Predne-Dome

Prednelan

Prednicen

Predni-Dome

Predniliderm

Predniretard

Prednis

Prednisolona

Prednisolona [INN-Spanish]

prednisolone

Prednisolone (anhydrous)

Prednisolone (JP15/USP/INN)

Prednisolone [INN:BAN:JAN]

Prednisolone acetate

Prednisolone Acetate

Prednisolone sodium phosphate

Prednisolone Sodium Phosphate

Prednisolone tebutate

Prednisolone Tebutate

Prednisolonum

Prednisolonum [INN-Latin]

Predonin

Predonine

Prelone

Prenolone

Prestwick_404

Prestwick0_000274

Prestwick1_000274

Prestwick2_000274

Prestwick3_000274

Rolisone

S1737_Selleck

SAM002264639

Scherisolon

SMR000718761

Solone

SPBio_002367

Steran

Sterane

Sterolone

Supercortisol

Ulacort

Ultra Pred

Ultracorten H

Ultracortene H

Ultracortene-H

Ultracortene-hydrogen

Ultracortene-Hydrogen

UNII-9PHQ9Y1OLM

ZINC03833821

δ(1)-dehydrocortisol

δ(1)-dehydrohydrocortisone

δ(1)-hydrocortisone

Leflunomide

Approved, Investigational

Phase 4

75706-12-6

3899

Synonyms:

210165-51-8

4-Isoxazolecarboxamide, 5-methyl-N-(4-(trifluoromethyl)phenyl

4-isoxazolecarboxamide,5-methyl-N-(4-(trifluoromethyl)phenyl)

5-Methylisoxazole-4-(4-trifluoromethyl)carboxanilide

5-Methylisoxazole-4-(4-trifluoromethylcarboxanilide)

5-Methylisoxazole-4-carboxylate (4-trifluoromethyl)anilide

5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide

5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide

5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide

5-methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide

5-methyl-N-[4-(trifluoromethyl)phenyl]isoxazole-4-carboxamide

75706-12-6

a,a,a-trifluoro-5-Methyl-4-isoxazolecarboxy-P-toluidide

A77 1486

AB00052389

AC1L1GYK

AC1Q2EVA

AC-6796

AKOS000265193

alpha,alpha,alpha-trifluoro-5-Methyl-4-isoxazolecarboxy-P-toluidide

alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide

alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-P-toluidide

AP-501/42475599

Arava

Arava (TN)

Arava, Leflunomide

Aventis behring brand OF leflunomide

Aventis Behring Brand of Leflunomide

Aventis brand OF leflunomide

Aventis Brand of Leflunomide

Aventis pharma brand OF leflunomide

Aventis Pharma Brand of Leflunomide

BIDD:PXR0189

BPBio1_000930

BRD-K78692225-001-03-9

BSPBio_000844

C045463

C07905

CAS-75706-12-6

CHEBI:6402

CHEMBL960

CID3899

D00749

DB01097

DivK1c_000916

EU-0100649

HMS1570K06

HMS1922M06

HMS2090O12

HMS502N18

Hoechst brand OF leflunomide

Hoechst Brand of Leflunomide

HSDB 7289

HWA 486

HWA-486

I06-2131

IDI1_000916

KBio1_000916

KBio2_000802

KBio2_003370

KBio2_005938

KBioSS_000802

L 5025

L5025_SIGMA

Leflunomid

Leflunomida

Leflunomida [INN-Spanish]

leflunomide

Leflunomide

Leflunomide (JAN/USAN/INN)

Leflunomide [USAN:INN]

Leflunomidum

Leflunomidum [INN-Latin]

lefunamide

Lefunomide

Lefunomide [Inn-Spanish]

Lefunomide [INN-Spanish]

Lopac0_000649

Lopac-L-5025

LS-86580

MLS000069648

MLS-0003109.0001

MLS001076267

MolPort-002-345-613

N-(4'-Trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide

N-(4-trifluoromethyphenyl)-5-methylisoxazole-4-carboxamide

N-(4-Trifluoromethyphenyl)-5-methylisoxazole-4-carboxamide

NCGC00015610-01

NCGC00015610-02

NCGC00015610-03

NCGC00015610-07

NCGC00015610-12

NCGC00022625-03

NCGC00022625-04

NCGC00022625-05

NCGC00022625-06

NCGC00022625-07

NCGC00022625-08

NINDS_000916

NSC677411

Prestwick_87

Prestwick0_000772

Prestwick1_000772

Prestwick2_000772

Prestwick3_000772

RS-34821

S1247_Selleck

SMR000058209

SPBio_002783

Spectrum_000322

SPECTRUM1503927

Spectrum5_000850

SU 101

SU 101 (pharmaceutical)

SU101

SU-101

TL8005179

UNII-G162GK9U4W

ZINC00004840

α,α,α-trifluoro-5-methyl-4-isoxazolecarboxy-P-toluidide

Betamethasone

Approved, Vet_approved

Phase 4

378-44-9

9782

Synonyms:

.beta.-Methasone

.beta.-Methasone alcohol

1,4-Pregnadiene-3,20-dione-9alpha-fluoro-16 beta-methyl-11 beta,17alpha,21-triol

16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione

16b-Methyl-1,4-pregnadiene-9a-fluoro-11b,17a,21-triol-3,20-dione

16β-methyl-1,4-pregnadiene-9α-fluoro-11β,17α,21-triol-3,20-dione

16β-Methyl-1,4-pregnadiene-9α-fluoro-11β,17α,21-triol-3,20-dione

24024-03-1

34166_FLUKA

34166_RIEDEL

378-44-9

4-08-00-03501 (Beilstein Handbook Reference)

9.alpha.-Fluoro-16.beta.-methylprednisolone

9a-fluoro-16b-Methylprednisolone

9alpha-Fluoro-16 beta-methyl-prednisolone

9alpha-fluoro-16beta-Methylprednisolone

9alpha-Fluoro-16beta-methylprednisolone

9-alpha-Fluoro-16-beta-methylprednisolone

9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione

9-Fluoro-11.beta.,17,21-trihydroxy-16.beta.-methylpregna-1,4-diene-3,20-dione

9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione

9-Fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione

9-Fluoro-16.beta.-methylprednisolone

9-fluoro-16beta-Methylprednisolone

9-Fluoro-16beta-methylprednisolone

9-fluoro-16b-Methylprednisolone

9-fluoro-16β-methylprednisolone

9-Fluoro-16β-methylprednisolone

9α-fluoro-16β-methylprednisolone

9α-Fluoro-16β-methylprednisolone

AC1L1EYE

AC1L1TT4

AC1Q5HJZ

AKOS001582690

AR-1A7284

AR-1H5595

B1837

B7005_SIAL

B7005_SIGMA

B9675_SIAL

Bebate

Becort

Bedifos

Betacorlan

Betacortril

Betadexamethasone

Betafluorene

Betamamallet

Betametasona

Betametasona [INN-Spanish]

Betametasone

Betametasone [DCIT]

betamethasone

beta-Methasone

Betamethasone

Betamethasone (JP15/USP/INN)

Betamethasone [USAN:BAN:INN:JAN]

Betamethasone [USAN:INN:BAN:JAN]

beta-Methasone alcohol

Betamethasone alcohol

Betamethasone Base

Betamethasone cream

Betamethasone Valearate

Betamethasonum

Betamethasonum [INN-Latin]

Betamethasonvalerat Mikron

Betamethazone

Betapredol

Betasolon

Betnelan

Betsolan

BIDD:PXR0047

b-Methasone alcohol

BPBio1_000533

BRD-A35108200-001-04-7

BRD-K39188321-001-03-9

BRN 3176546

BSPBio_000483

C22H29FO5

Celestene

Celeston

Celestona

Celestone

Celestone Syrup and Tablets

Celestone, Betadexamethasone, Flubenisolone, Sch-4831, NCS-39470, Betamethasone

Cellestoderm

CHEBI:3077

CHEMBL632

CID3003

CID9782

Cidoten

CPD000339803

D00244

D1961

DB00443

Desacort-Beta

EINECS 206-825-4

Flubenisolone

HMS1569I05

Hormezon

HSDB 3015

I06-0121

KST-1A3042

LS-118466

LT00441022

Luxiq

Luxiqo

Methazon

MLS000686794

MLS000859943

MLS001066413

MLS001332616

MLS002153244

MLS-0310139.0001

MolPort-003-845-025

MolPort-007-981-051

NCGC00164401-01

NCGC00164401-02

NSC 39470

NSC39470

NSC-39470

Prestwick_703

Prestwick0_000362

Prestwick1_000362

Prestwick2_000362

Prestwick3_000362

Rinderon

Rinderon (TN)

Rinderon A

S1500_Selleck

SAM002589959

SCH 4831

SCH-4831

SMP1_000043

SMR000058601

SMR000339803

SPBio_002404

UNII-9842X06Q6M

Valisone

Visubeta

ZINC03876136

β-methasone alcohol

Methylprednisolone

Approved, Vet_approved

Phase 4,Phase 2

83-43-2

6741

Synonyms:

(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione

(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione

(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione

.DELTA.1-6.alpha.-Methylhydrocortisone

11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione

11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione

11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione

11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione

121673-01-6

1-dehydro-6alpha-Methylhydrocortisone

1-Dehydro-6alpha-methylhydrocortisone

1-dehydro-6a-Methylhydrocortisone

1-dehydro-6α-methylhydrocortisone

4-08-00-03498 (Beilstein Handbook Reference)

46436_FLUKA

46436_RIEDEL

570-35-4

6 Methylprednisolone

6.alpha.-Methylprednisolone

6923-42-8

6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione

6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione

6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione

6alpha-Methylprednisolone

6-alpha-Methylprednisolone

6a-Methyl-11b,17a,21-triol-1,4-pregnadiene-3,20-dione

6-Methylprednisolone

6α-methyl-11β,17α,21-triol-1,4-pregnadiene-3,20-dione

83-43-2

AC1L1N7A

Artisone-wyeth

Artisone-Wyeth

Besonia

Bio-0658

BPBio1_000174

BRD-K35240538-001-03-1

BRN 2340300

BSPBio_000158

CHEBI:6888

CHEMBL650

CID6741

CPD000058330

D00407

D008775

DB00959

delta(1)-6alpha-Methylhydrocortisone

Delta(1)-6alpha-Methylhydrocortisone

delta(1)-6a-Methylhydrocortisone

delta(sup 1)-6-alpha-Methylhydrocortisone

Depo-Medrol (acetate)

Dopomedrol

EINECS 201-476-4

Esametone

Firmacort

HMS1568H20

HMS2090B13

HSDB 3127

Lemod

LMST02030178

LS-118498

M0639_SIGMA

M1665

Medesone

Medixon

Medlone 21

Medrate

Medric acid

Medrol

Medrol (TN)

Medrol adt pak

Medrol Adt Pak

Medrol dosepak

Medrol Dosepak

Medrol, Solu-Medrol, Medrone, Methylprednisolone

Medrone

MEPRDL

Mesopren

Metastab

Methyleneprednisolone

Methylprednisolon

methylprednisolone

Methylprednisolone

Methylprednisolone (JP15/USP/INN)

Methylprednisolone [USAN:INN:BAN:JAN]

Methylprednisolone, 6-alpha

Methylprednisolonum

Methylprednisolonum [INN-Latin]

methylprenisolone

Metilbetasone

Metilprednisolona

Metilprednisolona [INN-Spanish]

Metilprednisolone

Metilprednisolone [Dcit]

Metilprednisolone [DCIT]

Metipred

Metrisone

Metrocort

Metysolon

MLS000028541

MLS001148159

MLS002207191

Moderin

MolPort-002-528-554

NCGC00022735-03

NCI60_001657

Nirypan

Noretona

NSC19987

NSC-19987

Predni N Tablinen

Prednol- L

Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)

Prestwick_622

Prestwick0_000279

Prestwick1_000279

Prestwick2_000279

Prestwick3_000279

Promacortine

Reactenol

S1733_Selleck

SAM002589984

Sieropresol

SMR000058330

Solomet

SPBio_002377

Summicort

Suprametil

U 7532

UNII-X4W7ZR7023

Urbason

Urbasone

Wyacort

ZINC03875560

δ(1)-6a-methylhydrocortisone

δ(1)-6α-methylhydrocortisone

glucocorticoids

Phase 4,Phase 2,Phase 3

Hormone Antagonists

Phase 4,Phase 2,Phase 3

Hormones

Phase 4,Phase 2,Phase 3

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 4,Phase 2,Phase 3

Immunoglobulin G

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1

Antibodies

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1

Immunoglobulins

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1

Anti-Inflammatory Agents

Phase 4,Phase 2,Phase 3

Antineoplastic Agents, Hormonal

Phase 4,Phase 2,Phase 3

Antirheumatic Agents

Phase 4,Phase 1,Phase 2

Prednisolone acetate

Phase 4,Phase 2

Betamethasone Valerate

Phase 4

2152-44-5

Methylprednisolone acetate

Phase 4,Phase 2

Methylprednisolone Hemisuccinate

Phase 4,Phase 2

Immunosuppressive Agents

Phase 4,Phase 2,Phase 1

Prednisolone hemisuccinate

Phase 4,Phase 2

Prednisolone phosphate

Phase 4,Phase 2

Liver Extracts

Phase 4

Betamethasone benzoate

Phase 4

Betamethasone dipropionate, betamethasone sodium phosphate drug combination

Phase 4

Betamethasone sodium phosphate

Phase 4

Betamethasone-17,21-dipropionate

Phase 4

rituximab

Approved

Phase 1, Phase 2

174722-31-7

10201696

Mycophenolic acid

Approved

Phase 2

24280-93-1

446541

Synonyms:

(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate

(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid

Acid, mycophenolic

Acide mycophenolique

acido Micofenolico

Acido micofenolico

Acidum mycophenolicum

Melbex

micofenolico acido

Micofenolico acido

Mycophenoic acid

Mycophenolate

Mycophenolsaeure

Mycophenolsäure

Myfortic

Mycophenolate mofetil

Approved, Investigational

Phase 2

128794-94-5

5281078

Synonyms:

115007-34-6

128794-94-5

140401-05-4

2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate

2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate

2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate

2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate

2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate

2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate

2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid

4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)

AC-1562

AC1NQXZW

AC1Q6O6X

AR-1J6939

BB_NC-2566

C07908

C23H31NO7

Cellcept

CellCept

Cellcept (TN)

CellCept, RS 61443, TM-MMF, Mycophenolate mofetil

CHEMBL1456

CID5281078

D00752

DB00688

HMS2090A03

HSDB 7436

I01-0898

I06-1947

LS-172272

LS-75572

ME-MPA

MMF

MMF CellCept(TM)

MolPort-000-883-800

Munoloc

mycophenolate mofetil

Mycophenolate mofetil (JAN/USAN)

Mycophenolate mofetil hydrochloride

Mycophenolate morpholinoethyl ester

Mycophenolate sodium

Mycophenolic acid mofetil

Mycophenolic acid morpholinoethyl ester

Mycophenylate mofetil

Myfortic

NCGC00159459-02

NCGC00159459-03

NSC724229

R-99

RS 61443

RS-61443

RS-61443-190

S1501_Selleck

Sodium mycophenolate

TL8000648

TM-MMF

UNII-9242ECW6R0

ZINC21297660

Anti-Bacterial Agents

Phase 2,Phase 1

Antibiotics, Antitubercular

Phase 2

Anti-Infective Agents

Phase 2,Phase 1

Antitubercular Agents

Phase 2

Lenalidomide

Approved

Phase 1

191732-72-6

216326

Synonyms:

191732-72-6

1-oxo-2-(2,6-Dioxopiperidin-3-yl)-4-aminoisoindoline

3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione

3-(4-amino-1-Oxoisoindolin-2-yl)piperidine-2,6-dione

3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione

3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione

3-(7-Amino-3-oxo-1H-isoindol-2-yl)-piperidine-2,6-dione

346670-73-3

443912-14-9

AC1L50II

AC-914

AKOS005146276

ALBB-015321

Bio-0168

C467567

CC 5013

CC5013

CC-5013

CC-5013, Revlimid, Lenalidomide

CDC 501

CDC-501

CDC-5013

Celgene brand of lenalidomide

Celgene brand OF lenalidomide

CHEMBL848

CID216326

D04687

DB00480

EC-000.2340

ENMD-0997

I06-0831

IMid-1

IMID-1

IMiD3

IMiD3 cpd

IMiD3 CPD

IMID-5013

lenalidomide

Lenalidomide

Lenalidomide (USAN/INN)

Lenalidomide [USAN]

LS-184040

MolPort-003-848-370

NCGC00167491-01

NSC747972

Revamid

Revimid

Revlimid

Revlimid (Celgene)

Revlimid (TN)

S1029_Selleck

STK639603

Thalidomide analog CC-5013

UNII-F0P408N6V4

Angiogenesis Inhibitors

Phase 1

Angiogenesis Modulating Agents

Phase 1

Fluorides

Early Phase 1

Fluorodeoxyglucose F18

Early Phase 1

Deoxyglucose

Early Phase 1

Radiopharmaceuticals

Early Phase 1

Vaccines

Autoantibodies

Interventional clinical trials:

(show all 19)

#	Name	Status	NCT ID	Phase	Drugs
1	To Evaluate the Clinical Efficacy of Iguratimod in the Treatment of IgG4 Related Disease (IgG4-RD) With Mild Symptom	Recruiting	NCT03368274	Phase 4	T 614
2	Leflunomide for Maintenance of Remission in IgG4 Related Disease	Recruiting	NCT02703194	Phase 4	Prednisone;Leflunomide
3	Glucocorticoids in Patients With IgG4-RD	Unknown status	NCT01758393	Phase 2, Phase 3	Prednisone
4	Study to Evaluate the Effect of XmAb®5871 on Disease Activity in Patients With IgG4-Related Disease (RD)	Completed	NCT02725476	Phase 2
5	Rituximab in IgG4-RD: A Phase 1-2 Trial	Completed	NCT01584388	Phase 1, Phase 2	Rituximab
6	Study of Treatment Response on IgG4 Related Disease (IgG4RD)	Recruiting	NCT02458196	Phase 2	Prednisone;Prednisone and Mycophenolate mofetil
7	Treatment of IgG4-Related Disease With Revlimid and Rituximab	Recruiting	NCT02705638	Phase 1	Rituximab;Lenalidomide
8	Follicular Helper T Cells: Biological Marker and Involvement in the Physiopathology of the IgG4-related Disease	Completed	NCT02899039	Not Applicable
9	Retrospective Study for Diagnosis of Undetected IgG4 Related Diseases in Patients With High Serum IgG4 Levels.	Completed	NCT02229448
10	A Prospective Cohort Study of IgG4RD in China	Recruiting	NCT01670695
11	18F-FDG PET/CT for IgG4-Related Disease	Recruiting	NCT01665196	Early Phase 1	18F-FDG
12	National Registry of IgG4-RD in China	Recruiting	NCT03023371
13	Bile Usefulness for Detecting IgG4-related Sclerosing Cholangitis	Recruiting	NCT02616705
14	Comparative Autoantibody and Immunologic Cell Marker Study	Enrolling by invitation	NCT02422875
15	Plasmablast Detection From IgG4-Related Disease Patients	Not yet recruiting	NCT03466970
16	A Laboratory Scan of Patients With Aortic Aneurysms to IgG4 Levels in the Blood	Not yet recruiting	NCT03267875	Not Applicable
17	Meir Medical Center Rheumatologic Biobank	Not yet recruiting	NCT03473912
18	Characterization of Tissular T Follicular Helper Cells in IgG4-RD	Not yet recruiting	NCT02872441	Not Applicable
19	Evaluation Of Pleural Effusion At Assiut University Hospital	Not yet recruiting	NCT03260088

Search NIH Clinical Center for Igg4-Related Disease

Sources

Genetic Tests for Igg4-Related Disease

Sources

Anatomical Context for Igg4-Related Disease

MalaCards organs/tissues related to Igg4-Related Disease:

⁴¹

Salivary Gland, Skin, Lymph Node, Thyroid, T Cells, Lung, Liver

Sources

Publications for Igg4-Related Disease

Articles related to Igg4-Related Disease:

(show top 50) (show all 271)

#	Title	Authors	Year
1	Treatment and outcomes in patients with IgG4-related disease using the IgG4 responder index. ( 29452298 )	FernA!ndez-Codina A....MartA-nez-Valle F.	2018
2	Interleukin-4 contributes to the shift of balance of IgG subclasses toward IgG4 in IgG4-related disease. ( 29861381 )	Akiyama M....Takeuchi T.	2018
3	Paratesticular Fibrous Pseudotumor: A New Entity of IgG4-Related Disease? ( 29970445 )	ChangChien Y.C....Magyar L.	2018
4	IgG4-related disease presenting with scarring alopecia of the scalp. ( 29892674 )	Hoesly P.M....Sluzevich J.C.	2018
5	Orbital Granulomatosis With Polyangiitis Mimicking IgG4-Related Disease in a 12-Year-Old Male. ( 29366363 )	Drobysheva A....Rakheja D.	2018
6	IgG4-Related Disease Mimicking Crohn's Disease: A Case Report and Review of Literature. ( 29417330 )	Ciccone F....Latella G.	2018
7	IgG4-Related Disease of the Thyroid Gland Requiring Emergent Total Thyroidectomy: A Case Report. ( 29855801 )	Zhao Z....Lim K.H.	2018
8	IgG4-related disease and intracranial hypertenstion: Case report of a novel mechanistic association. ( 29406918 )	Healy J....Tagg N.T.	2018
9	Risk factors of relapse following glucocorticoid tapering in IgG4-related disease. ( 29846165 )	Sasaki T....Takeuchi T.	2018
10	Glucocorticoid receptor expression in resident and hematopoietic cells in IgG4-related disease. ( 29434340 )	Iguchi T....Yanagita M.	2018
11	IgG4-related disease: features and treatment response in a multi-ethnic cohort in Singapore. ( 29846168 )	Fong W....Leung Y.Y.	2018
12	The Clinicopathologic Spectrum of IgG4-Related Disease. ( 29866638 )	Obiorah I.E....A9zdemirli M.	2018
13	IgG4-Related Disease with Lung Involvement. ( 29935778 )	Fernandez GarcA-a D....Benavent Corai V.	2018
14	Two cases of generalized pustular psoriasis complicated by IgG4-related disease. ( 29709076 )	Miyazawa H....Shimizu H.	2018
15	Clivus lesion revealed inflammatory pseudotumor associated with IgG4-related disease: a case report. ( 29966794 )	Tang H....Gong Y.	2018
16	IgG4-related disease with skin, submaxillary and pulmonary involvement. ( 29938895 )	Tous-Romero F....Postigo-Llorente C.	2018
17	Sustained clinical response after single course of rituximab as first-line monotherapy in adult-onset asthma and periocular xanthogranulomas syndrome associated with IgG4-related disease: A case report. ( 29952960 )	Pomponio G....Gabrielli A.	2018
18	Comment on the article entitled &quot;Antineutrophil cytoplasmic antibody-associated vasculitides and IgG4-related disease: A new overlap syndrome&quot; (Autoimmunity Reviews 16 (2017) 1036-1043). ( 29427824 )	Goulabchand R....Guilpain P.	2018
19	The Utility of FDG PET/CT in IgG4-Related Disease with a Focus on Coronary Artery Involvement. ( 29391913 )	Huang H.L....Lam W.W.	2018
20	Idiopathic thrombocytopenic purpura in a patient with IgG4-related disease. ( 29888414 )	Jimura N....Kanekura T.	2018
21	IgG4-related disease: review of the histopathologic features, differential diagnosis, and therapeutic approach. ( 29924455 )	Bledsoe J.R....Deshpande V.	2018
22	Combined membranous nephropathy and tubulointerstitial nephritis as a rare renal manifestation of IgG4-related disease: a case-based literature review. ( 29388171 )	Zhang W....Wynne D.	2018
23	Factors in glucocorticoid regimens associated with treatment response and relapses of IgG4-related disease: a multicentre study. ( 29980706 )	Shirakashi M....Mimori T.	2018
24	Retroperitoneal fibrosis associated with IgG4-related disease diagnosed by prostate biopsy developed with acute post-renal renal failure: A case report. ( 29034178 )	Inui K....Tomita Y.	2018
25	Hepatobiliary and Pancreatic: Burkitt lymphoma mimicking IgG4-related disease. ( 29808497 )	Azuma S....Yazumi S.	2018
26	IgG4-related disease of the central and peripheral nervous systems. ( 29413316 )	AbdelRazek M.A....Stone J.H.	2018
27	Rituximab for retroperitoneal fibrosis due toA IgG4-related disease: A case report and literature review. ( 29845002 )	Almeqdadi M....Jaber B.L.	2018
28	No specific imaging pattern can help differentiate IgG4-related disease from idiopathic retroperitoneal fibrosis: 18 histologically proven cases. ( 29465374 )	Forestier A....Lambert M.	2018
29	LatY136F knock-in mouse model for human IgG4-related disease. ( 29902238 )	Yamada K....Kawano M.	2018
30	Hepatitis B virus Reactivation During Steroid Treatment of IgG4-Related Disease. ( 29311390 )	Shingina A....Gulamhusein A.	2018
31	IgG4-related disease of the mitral valve demonstrated by immunohistochemistry. ( 29437558 )	Tiong B.K....Brahn E.	2018
32	IgG4-related disease: association between chronic rhino-sinusitis and systemic symptoms. ( 29948263 )	Gao Y....Wang Z.G.	2018
33	The tarsal plate manifestation of IgG4-related disease. ( 29926366 )	Verhoekx J.S.N....Paridaens D.	2018
34	IgG4-related disease. ( 28871762 )	Vikse J....Norheim K.B.	2017
35	IgG4-related disease in autoimmune lymphoproliferative syndrome. ( 28478106 )	van de Ven A.A.J.M....Kollert F.	2017
36	IgG4-related disease with possible myocardial involvement. ( 29277579 )	LA^pez Vivancos J....GarcA-a Cors M.	2017
37	Antineutrophil cytoplasmic antibody-associated vasculitides and IgG4-related disease: A new overlap syndrome. ( 28780079 )	Danlos F.X....Terrier B.	2017
38	Lymphomas in IgG4-related disease: clinicopathologic features in a Western population. ( 29285637 )	Bledsoe J.R....Ferry J.A.	2017
39	Unexpected Fibrosing Mediastinitis Shown on FDG PET/CT in a Patient With IgG4-Related Disease. ( 28806261 )	Kan Y....Yang J.	2017
40	IgG4-related disease as the differential diagnosis of hypophysitis. ( 28898148 )	Jolobe O.M.	2017
41	Idiopathic retroperitoneal fibrosis and its overlap with IgG4-related disease. ( 28070877 )	Rossi G.M....Vaglio A.	2017
42	IL-1 family cytokines and receptors in IgG4-related disease. ( 28823915 )	Capecchi R....Migliorini P.	2017
43	IgG4-related disease: with emphasis on the biopsy diagnosis of autoimmune pancreatitis and sclerosing cholangitis. ( 29196804 )	Detlefsen S....KlAPppel G.	2017
44	IgG4-Related Disease Manifesting as Interstitial Nephritis Accompanied by Hypophysitis. ( 28552902 )	Matsuda K....Nagasawa T.	2017
45	IgG4-related disease and IgG4-mediated neurological autoimmune disorders: One and the same? ( 28778436 )	Delgado-GarcA-a G....Corona-VA!zquez T.	2017
46	IgG4-related disease of the lung: a rare differential diagnosis to lung cancer after positive positron emission tomography and biopsy. ( 28950319 )	Zehnder A....Schmid R.A.	2017
47	A Challenging Diagnosis of IgG4-Related Disease When Understanding Limitations of Laboratory Testing Was Pivotal. ( 28828007 )	Xu V.Y.Y....Chan P.C.	2017
48	IgG4-related Disease - A Patient with Multiple Organ Involvement. ( 28922106 )	PrA^cha M....SedlA!A8kovA! L.	2017
49	IgG4-related disease presenting as posterior scleritis and vitritis, progressing to multifocal orbital involvement. ( 28438752 )	Reynolds G.L....Sharma S.	2017
50	IgG4-Related Disease With Orbital Pseudotumors Treated With Rituximab Combined With Palpebral Surgery. ( 28055067 )	Aouidad I....Viguier M.	2017

Sources

Genes for Igg4-Related Disease

Genes related to Igg4-Related Disease (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	PDCD1	Programmed Cell Death 1	Protein Coding	16.82	GeneCards inferred via : Publications (show sections)
2	TNFSF13B	TNF Superfamily Member 13b	Protein Coding	16.82	GeneCards inferred via : Publications (show sections)
3	PHB	Prohibitin	Protein Coding	16.82	GeneCards inferred via : Publications (show sections)
4	TNFSF13	TNF Superfamily Member 13	Protein Coding	16.82	GeneCards inferred via : Publications (show sections)
5	MARCO	Macrophage Receptor With Collagenous Structure	Protein Coding	6.82	GeneCards inferred via : Publications (show sections)

Sources

Variations for Igg4-Related Disease

Sources

Expression for Igg4-Related Disease

Search GEO for disease gene expression data for Igg4-Related Disease.

Sources

Pathways for Igg4-Related Disease

Pathways related to Igg4-Related Disease according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	TRAF Pathway ⁶⁴ Show member pathways 14-3-3 Induced Apoptosis ⁶⁴ TNF Superfamily Pathway ⁶⁴ Toll-Like Receptors Pathway ⁶⁴	11.85	TNFSF13 TNFSF13B
2	Spinal Cord Injury ¹	11.34	TNFSF13 TNFSF13B
3	Rheumatoid arthritis ³⁷	11.11	TNFSF13 TNFSF13B
4	Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway ²² Show member pathways Apoptosis and survival Anti-apoptotic TNFs/NF-kB/IAP pathway ²²	10.82	TNFSF13 TNFSF13B
5	TNFs bind their physiological receptors ⁶⁶	10.1	TNFSF13 TNFSF13B

Sources

GO Terms for Igg4-Related Disease

Biological processes related to Igg4-Related Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	signal transduction	GO:0007165	9.26	PDCD1 PHB TNFSF13 TNFSF13B
2	tumor necrosis factor-mediated signaling pathway	GO:0033209	9.16	TNFSF13 TNFSF13B
3	T cell costimulation	GO:0031295	8.62	PDCD1 TNFSF13B

Molecular functions related to Igg4-Related Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cytokine activity	GO:0005125	8.96	TNFSF13 TNFSF13B
2	tumor necrosis factor receptor binding	GO:0005164	8.62	TNFSF13 TNFSF13B

Sources

Sources for Igg4-Related Disease

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia