MCID: IGG009
MIFTS: 18

Igg4-Related Ophthalmic Disease

Categories: Bone diseases, Eye diseases, Rare diseases

Aliases & Classifications for Igg4-Related Ophthalmic Disease

MalaCards integrated aliases for Igg4-Related Ophthalmic Disease:

Name: Igg4-Related Ophthalmic Disease 58

Characteristics:

Orphanet epidemiological data:

58
igg4-related ophthalmic disease
Inheritance: Not applicable; Age of onset: Adult,Elderly;

Classifications:

Orphanet: 58  
Rare eye diseases
Rare systemic and rhumatological diseases


External Ids:

ICD10 via Orphanet 33 H05.1
Orphanet 58 ORPHA449563

Summaries for Igg4-Related Ophthalmic Disease

MalaCards based summary : Igg4-Related Ophthalmic Disease is related to igg4-related disease and exophthalmos. The drugs Immunoglobulin G and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include eye, bone and b cells.

Related Diseases for Igg4-Related Ophthalmic Disease

Diseases related to Igg4-Related Ophthalmic Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 34)
# Related Disease Score Top Affiliating Genes
1 igg4-related disease 10.4
2 exophthalmos 10.3
3 orbital disease 10.3
4 dacryoadenitis 10.3
5 myositis 10.2
6 marginal zone b-cell lymphoma 10.2
7 paranasal sinus disease 10.1
8 optic nerve disease 10.1
9 b-cell lymphoma 10.1
10 neuropathy 10.1
11 orbital plasma cell granuloma 10.1
12 hypereosinophilic syndrome 10.1
13 lymphoma, mucosa-associated lymphoid type 9.9
14 lacrimal duct defect 9.9
15 sarcoidosis 1 9.9
16 strabismus 9.9
17 ptosis 9.9
18 nodal marginal zone lymphoma 9.9
19 alternating exotropia 9.9
20 exotropia 9.9
21 panuveitis 9.9
22 aseptic meningitis 9.9
23 mikulicz disease 9.9
24 uveitis 9.9
25 hypothyroidism 9.9
26 kidney disease 9.9
27 intraocular lymphoma 9.9
28 hyperthyroidism 9.9
29 herpes simplex 9.9
30 mechanical strabismus 9.9
31 iridocyclitis 9.9
32 meningitis 9.9
33 hypertropia 9.9
34 progressive transformation of germinal centers 9.9

Graphical network of the top 20 diseases related to Igg4-Related Ophthalmic Disease:



Diseases related to Igg4-Related Ophthalmic Disease

Symptoms & Phenotypes for Igg4-Related Ophthalmic Disease

Drugs & Therapeutics for Igg4-Related Ophthalmic Disease

Drugs for Igg4-Related Ophthalmic Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Immunoglobulin G
2 Immunologic Factors
3 Immunoglobulins
4 Antibodies

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Infraorbital Nerve Involvement on Magnetic Resonance Imaging in European Patients With IgG4-related Ophthalmic Disease Completed NCT03690908
2 Infraorbital Nerve Involvement on Magnetic Resonance Imaging in European Patients With IgG4-related Ophthalmic Disease Completed NCT02900859

Search NIH Clinical Center for Igg4-Related Ophthalmic Disease

Genetic Tests for Igg4-Related Ophthalmic Disease

Anatomical Context for Igg4-Related Ophthalmic Disease

MalaCards organs/tissues related to Igg4-Related Ophthalmic Disease:

40
Eye, Bone, B Cells, Thyroid, T Cells

Publications for Igg4-Related Ophthalmic Disease

Articles related to Igg4-Related Ophthalmic Disease:

(show top 50) (show all 61)
# Title Authors PMID Year
1
Orbital inflammation and colitis in pediatric IgG4-related disease: A case report and review of the literature. 61
31804176 2019
2
[Clinical and pathological study on IgG4-related ophthalmic disease involving the lacrimal gland]. 61
31715680 2019
3
IgG4-related Ophthalmic Disease in Idiopathic Sclerosing and Non-Sclerosing Orbital Inflammation: A 25-Year Experience. 61
31154852 2019
4
IgG4-related Ophthalmic Disease with Proptosis. 61
31666463 2019
5
Long-term outcomes of ocular adnexal lesions in IgG4-related ophthalmic disease. 61
31272957 2019
6
MULTIMODAL IMAGING OF IGG4-RELATED PAPILLITIS AND RETINAL DISEASE. 61
31343561 2019
7
IGG4-RELATED OPHTHALMIC DISEASE PRESENTING AS CHOROIDAL AND ORBITAL LESIONS. 61
28346259 2019
8
Magnetic resonance imaging indicator of the causes of optic neuropathy in IgG4-related ophthalmic disease. 61
31215395 2019
9
Occult Nasolacrimal Duct Obstruction Secondary to IgG4-Related Ophthalmic Disease. 61
30882590 2019
10
IgG4-positive Cell Quantification Distinguishes Between Inflammatory and Noninflammatory Diseases of the Orbit. 61
30950839 2019
11
Distinguishing IgG4-Related Ophthalmic Disease From Graves Orbitopathy. 61
30124607 2019
12
Ocular adnexal marginal zone lymphoma arising in a patient with IgG4-related ophthalmic disease. 61
27686866 2019
13
A case of fatal osteolytic hypercalcemia complicated with IgG4-related ophthalmic disease leading to renal failure. 61
30109565 2019
14
IgG4-Related Ophthalmic Disease Presenting as Meningitis and Panuveitis. 61
31392068 2019
15
The natural course of IgG4-related ophthalmic disease after debulking surgery: a single-centre retrospective study. 61
31523717 2019
16
Clinical outcomes and pathological characteristics of immunoglobulin G4-related ophthalmic disease versus orbital inflammatory pseudotumor. 61
29050463 2019
17
Clinicoserological factors associated with response to steroid treatment and recurrence in patients with IgG4-related ophthalmic disease. 61
29420193 2018
18
Purpura fulminans with Lemierre's syndrome caused by Gemella bergeri and Eikenella corrodens: a case report. 61
30340466 2018
19
Longstanding IgG4-related Ophthalmic Disease Dramatically Improved after Steroid Therapy. 61
29780105 2018
20
The Case of IgG4-related Ophthalmic Disease Accompanied by Compressive Optic Neuropathy. 61
30042797 2018
21
The Case of IgG4-Related Ophthalmic Disease with Perivascular Lesions of Superior Ophthalmic Vein Associated with Optic Nerve Disturbance. 61
30042798 2018
22
[Clinical analysis of patients with orbital nonspecific inflammatory response diseases whose CT or MR images show enlargement of the infraorbital nerves]. 61
29996613 2018
23
IgG4-related ophthalmic disease involving extraocular muscles: case series. 61
29970061 2018
24
Risk factors for extraophthalmic involvement and treatment outcomes in patients with IgG4-related ophthalmic disease. 61
28972022 2018
25
Diagnosis of IgG4 - related ophthalmic disease in a group of patients with various lesions of the eye and orbits. 61
30701891 2018
26
Infraorbital Nerve Involvement on Magnetic Resonance Imaging in Igg4-Related Ophthalmic Disease: A Highly Suggestive Sign. 61
29566870 2018
27
Immunoglobulin G4-Related Disease: An Update. 61
29657677 2018
28
The 2017 Doyne Lecture: the orbit as a window to systemic disease. 61
29125145 2018
29
Immunoglobulin G4-related ophthalmic disease. 61
29675343 2018
30
Repeat Biopsy of IgG4-Related Ophthalmic Disease Identifies Superimposed Herpes Simplex Virus Infection: A Case Report. 61
28960118 2018
31
Orbital progressive transformation of germinal centers as part of the spectrum of IgG4-related ophthalmic disease: Clinicopathologic features of three cases. 61
29755273 2018
32
A clinicopathological study on IgG4-related ophthalmic disease. 61
30225231 2018
33
Frequency and distribution of CD4+CXCR5+ follicular B helper T cells within involved tissues in IgG4‑related ophthalmic disease. 61
29039547 2017
34
IgG4-related disease in the eye and ocular adnexa. 61
28858963 2017
35
Usefulness of Flow Cytometry in Diagnosis of IgG4-Related Ophthalmic Disease and Extranodal Marginal Zone B-Cell Lymphoma of the Ocular Adnexa. 61
28870925 2017
36
Change of Serum IgG4 in Patients with Ocular Adnexal Marginal Zone B Cell Lymphoma Associated with IgG4-Related Ophthalmic Disease After Treatment. 61
28514197 2017
37
Immunophenotypic profiles for distinguishing orbital mucosa-associated lymphoid tissue lymphoma from benign lymphoproliferative tumors. 61
28421369 2017
38
IgG4 Staining in Thyroid Eye Disease. 61
26359702 2017
39
Infraorbital nerve involvement on magnetic resonance imaging in European patients with IgG4-related ophthalmic disease: a specific sign. 61
27436015 2017
40
Clinical implications of serum IgG4 levels in patients with IgG4-related ophthalmic disease. 61
27215743 2017
41
Ophthalmic manifestations in IgG4-related disease: Clinical presentation and response to treatment in a French case-series. 61
28272212 2017
42
Orbital Involvement and Ocular Surface Changes in IgG4-Related Systemic Disease. 61
27467041 2016
43
Immunoglobulin G4-Related Ophthalmic Disease Involving the Sclera Misdiagnosed as Intraocular Tumor: Report of One Case. 61
27843911 2016
44
Bilateral IgG4-related ophthalmic disease: a strong indication for systemic imaging. 61
26719494 2016
45
Intraorbital corticosteroid injection for the treatment of IgG4-related ophthalmic disease. 61
26297732 2016
46
[Diagnostic Criteria for IgG4-related Ophthalmic Disease]. 61
27311268 2016
47
Immunoglobulin G4-related ophthalmic disease presenting as uveitis. 61
26188666 2015
48
Genome-Wide Analysis of Ocular Adnexal Lymphoproliferative Disorders Using High-Resolution Single Nucleotide Polymorphism Array. 61
26120819 2015
49
IgG4-Related Ophthalmic Disease: Pooling of Published Cases and Literature Review. 61
26141575 2015
50
Erratum to: Diagnostic criteria for IgG4-related ophthalmic disease. 61
25707353 2015

Variations for Igg4-Related Ophthalmic Disease

Expression for Igg4-Related Ophthalmic Disease

Search GEO for disease gene expression data for Igg4-Related Ophthalmic Disease.

Pathways for Igg4-Related Ophthalmic Disease

GO Terms for Igg4-Related Ophthalmic Disease

Sources for Igg4-Related Ophthalmic Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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