Aliases & Classifications for Ileitis

MalaCards integrated aliases for Ileitis:

Name: Ileitis 12 55 44 15 73
Crohn's Ileitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0060189
ICD10 33 K52.9
MeSH 44 D007079
NCIt 50 C84782
SNOMED-CT 68 52457000
UMLS 73 C0020877

Summaries for Ileitis

Disease Ontology : 12 An inflammatory bowel disease characterized by inflammation located in ileum, has symptom diarrhea, has symptom abdominal pain, often in the right lower quadrant, has symptom weight loss.

MalaCards based summary : Ileitis, also known as crohn's ileitis, is related to crohn's disease and pouchitis, and has symptoms including diarrhea, abdominal pain and weight loss. An important gene associated with Ileitis is NOD2 (Nucleotide Binding Oligomerization Domain Containing 2), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Clarithromycin and Clofazimine have been mentioned in the context of this disorder. Affiliated tissues include ileum, colon and bone, and related phenotypes are homeostasis/metabolism and hematopoietic system

Wikipedia : 76 Ileitis is an inflammation of the ileum, a portion of the small intestine. Crohn\'s ileitis is a type of... more...

Related Diseases for Ileitis

Diseases related to Ileitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 178)
# Related Disease Score Top Affiliating Genes
1 crohn's disease 32.6 IL6 NOD2 TLR4 TNF
2 pouchitis 31.3 NOD2 TLR4
3 lymphadenitis 30.7 NOD2 TLR4 TNF
4 ileocolitis 30.6 NOD2 TNF
5 mesenteric lymphadenitis 30.6 IL6 NOD2 TLR2
6 cystitis 30.3 IL6 TLR4 TNF
7 appendicitis 29.9 IL6 MPO TNF
8 typhoid fever 29.7 IL6 TLR4 TLR5 TNF
9 ulcerative colitis 29.6 IL6 MPO NOD2 TLR4 TNF
10 peritonitis 29.2 IL6 MPO TLR2 TNF
11 colitis 29.1 IL17A IL6 MPO NOD2 TLR4 TNF
12 inflammatory bowel disease 27.3 IL17A IL6 MPO NOD2 TLR2 TLR4
13 scorpion envenomation 10.8 IL6 TNF
14 spondylarthropathy 10.8 TLR4 TNF
15 granulomatous dermatitis 10.8 NOD2 TNF
16 prosthetic joint infection 10.8 TLR2 TLR4
17 leukomalacia 10.8 IL6 TNF
18 angioimmunoblastic lymphadenopathy with dysproteinemia 10.8 IL6 TNF
19 critical limb ischemia 10.7 IL6 TNF
20 streptococcal toxic-shock syndrome 10.7 IL6 TNF
21 null-cell leukemia 10.7 IL6 TNF
22 periodontitis, chronic 10.7 IL6 TLR2
23 rheumatoid lung disease 10.7 IL17A TNF
24 retinitis pigmentosa 55 10.7 IL6 TNF
25 laryngitis 10.6 IL6 TNF
26 crohn's colitis 10.6 NOD2 TNF
27 anterior uveitis 10.6 IL6 TLR2
28 posterior urethral valves 10.6 IL6 TNF
29 haemophilus influenzae 10.6 TLR2 TNF
30 neurosyphilis 10.6 IL17A TLR2
31 poems syndrome 10.6 IL6 TNF
32 trench fever 10.6 TLR2 TLR4 TNF
33 penicilliosis 10.5 TLR2 TLR4 TNF
34 alveolar echinococcosis 10.5 TLR2 TLR4 TNF
35 idiopathic neutropenia 10.5 IL6 TLR4 TNF
36 uterine anomalies 10.5 IL6 TLR4 TNF
37 brucellosis 10.5 IL6 TLR4 TNF
38 scrub typhus 10.5 TLR2 TLR4 TNF
39 pyelonephritis 10.5 IL6 TLR4 TNF
40 aggressive periodontitis 10.5 IL6 TLR4 TNF
41 middle ear disease 10.5 TLR2 TLR4 TNF
42 chorioamnionitis 10.5 IL6 TLR4 TNF
43 toxoplasmosis 10.5 IL6 TLR4 TNF
44 bronchiolitis 10.5 IL6 TLR4 TNF
45 leprosy 3 10.5 NOD2 TLR2 TNF
46 hidradenitis suppurativa 10.5 IL17A NOD2 TNF
47 hidradenitis 10.5 IL17A NOD2 TNF
48 viral pneumonia 10.5 IL17A IL6
49 myositis fibrosa 10.5 IL17A TLR2 TLR4
50 rosacea 10.5 IL6 TLR2 TNF

Graphical network of the top 20 diseases related to Ileitis:



Diseases related to Ileitis

Symptoms & Phenotypes for Ileitis

Symptoms:

12
  • diarrhea
  • abdominal pain
  • weight loss

MGI Mouse Phenotypes related to Ileitis:

46 (show all 15)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.23 FABP2 MPO IL17A NOD2 CCR3 IL6
2 hematopoietic system MP:0005397 10.22 MPO IL17A NOD2 CCR3 IL6 CSF2
3 growth/size/body region MP:0005378 10.19 FABP2 IL17A CSF2 IL6 XPNPEP1 TNF
4 immune system MP:0005387 10.17 MPO IL17A NOD2 CCR3 IL6 CSF2
5 cardiovascular system MP:0005385 10.14 MPO CSF2 IL6 XPNPEP1 TNF TLR4
6 digestive/alimentary MP:0005381 10.13 IL17A NOD2 IL6 XPNPEP1 TNF TLR4
7 adipose tissue MP:0005375 10.09 FABP2 IL6 CSF2 TNF TLR4 TLR2
8 mortality/aging MP:0010768 10.07 MPO IL17A CSF2 IL6 XPNPEP1 TNF
9 endocrine/exocrine gland MP:0005379 10.05 CSF2 IL6 IL17A XPNPEP1 TLR2 TNF
10 liver/biliary system MP:0005370 9.95 FABP2 IL6 XPNPEP1 TNF TLR4 TLR5
11 muscle MP:0005369 9.8 IL6 MPO XPNPEP1 TNF TLR2 TLR4
12 neoplasm MP:0002006 9.73 CSF2 IL6 XPNPEP1 TNF TLR4 TLR2
13 renal/urinary system MP:0005367 9.7 FABP2 IL17A IL6 CSF2 XPNPEP1 TLR4
14 respiratory system MP:0005388 9.61 IL17A CCR3 IL6 CSF2 XPNPEP1 TLR4
15 skeleton MP:0005390 9.23 IL17A CSF2 IL6 XPNPEP1 TNF TLR4

Drugs & Therapeutics for Ileitis

Drugs for Ileitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 428)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clarithromycin Approved Phase 4,Phase 3 81103-11-9 84029
2
Clofazimine Approved, Investigational Phase 4,Phase 3 2030-63-9 2794
3
Rifabutin Approved, Investigational Phase 4,Phase 3 72559-06-9 6323490
4
Adalimumab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 331731-18-1 16219006
5
Infliximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 170277-31-3
6
Hydrocortisone Approved, Vet_approved Phase 4,Not Applicable 50-23-7 5754
7
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 53-03-2 5865
8
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 83-43-2 6741
9
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-24-8 5755
10
Certolizumab pegol Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 428863-50-7
11
Azathioprine Approved Phase 4,Phase 3,Phase 2,Not Applicable 446-86-6 2265
12
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1994-09-7, 94-09-7 2337
13
Iron Approved Phase 4,Phase 3,Phase 2,Not Applicable 7439-89-6 23925
14 Vedolizumab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 943609-66-3
15
Azithromycin Approved Phase 4 83905-01-5 55185 447043
16
Metronidazole Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 443-48-1 4173
17
Budesonide Approved Phase 4,Phase 3,Phase 2,Phase 1 51333-22-3 63006 5281004
18
Methotrexate Approved Phase 4,Phase 3,Phase 2,Not Applicable 1959-05-2, 59-05-2 126941
19
Etidronic acid Approved Phase 4 7414-83-7, 2809-21-4 3305
20
Natalizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 189261-10-7
21
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 85721-33-1 2764
22
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 22916-47-8 4189
23
Midazolam Approved, Illicit Phase 4,Phase 1 59467-70-8 4192
24
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 1,Phase 2 73590-58-6 4594
25
Ondansetron Approved Phase 4,Phase 3 99614-02-5 4595
26
Everolimus Approved Phase 4 159351-69-6 6442177
27
Sirolimus Approved, Investigational Phase 4 53123-88-9 5284616 6436030 46835353
28
Angiotensin II Approved, Investigational Phase 4 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
29
Dextromethorphan Approved Phase 4,Phase 1 125-71-3 5360696 5362449
30
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 1,Not Applicable 93-14-1 3516
31
Losartan Approved Phase 4 114798-26-4 3961
32
Thioguanine Approved Phase 4 154-42-7 2723601
33
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 564-25-0 54671203
34
Vancomycin Approved Phase 4,Phase 2 1404-90-6 441141 14969
35
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
36
Sulfamethazine Approved, Investigational, Vet_approved Phase 4 57-68-1 5327
37
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
38
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 50-14-6 5280793
39 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
40
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 1406-16-2
41
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59-30-3 6037
42
Vitamin D3 Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 67-97-0 6221 5280795
43
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Not Applicable 58-05-9 143 6006
44
Menadione Approved, Nutraceutical Phase 4,Phase 1 58-27-5 4055
45
Phytonadione Approved, Investigational, Nutraceutical Phase 4,Phase 1 84-80-0 4812 5284607
46
Caffeine Approved, Nutraceutical Phase 4,Phase 1 58-08-2 2519
47 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
48 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
49 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
50 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 1206)
# Name Status NCT ID Phase Drugs
1 Treatment of Crohn's Disease With an Antibiotic Regimen Directed Against Mycobacterium Avium Paratuberculosis Unknown status NCT00513552 Phase 4 Rifabutin, Clarithromycin, and Clofazimine
2 A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Unknown status NCT01632462 Phase 4 VSL#3
3 Use of Combined Measurements of Serum Infliximab and Anti-infliximab Antibodies in the Treatment of Patients With Crohns Disease Failing Infliximab Therapy Unknown status NCT00851565 Phase 4
4 The Effect of Probiotics on Exacerbation of Inflammatory Bowel Disease Exacerbation (Crohn's Disease) Unknown status NCT01765998 Phase 4 Probiotic;Placebo
5 Effects of Enteral Nutrition and Corticosteroid on Intestinal Flora in Induction Remission of Crohn Disease in Adult Unknown status NCT02056418 Phase 4 corticosteroid
6 Discontinuation of Infliximab Therapy in Patients With Crohn's Disease During Sustained Complete Remission Unknown status NCT01817426 Phase 4 Infliximab
7 Evaluation of PET CT in the Management of Patients With Crohn's Disease. Unknown status NCT00731809 Phase 4
8 Comparison of a Nutritional Anti-Inflammatory Treatment to Steroids for Pediatric Crohn's Disease - the Molecular Basis Unknown status NCT00265772 Phase 4 MODULEN IBD (R) (specific Enteral Nutrition);prednisolon
9 Adverse Effects of Glucocorticoid Therapy on Bone in Childhood Crohn's Disease Unknown status NCT00609752 Phase 4 prednisolone
10 VSL#3 Treatment in Children With Crohn's Disease Unknown status NCT00367705 Phase 4
11 Optimizing Cimzia in Crohn's Patients Unknown status NCT01024647 Phase 4
12 The Effect of Probiotics on the Rate of Recovery of Inflammatory Bowel Disease Exacerbation, Endothelial Function, and Markers of Inflammation Unknown status NCT01078935 Phase 4
13 "Efficacy and Safety of Infliximab-biosimilar (Inflectra) Compared to Infliximab-innovator (Remicade) in Patients With Inflammatory Bowel Disease in Remission: the SIMILAR Trial" Unknown status NCT02452151 Phase 4 Infliximab-Biosimilar;Infliximab-Innovator
14 Precision Dosing of Infliximab Versus Conventional Dosing of Infliximab Unknown status NCT02453776 Phase 4 PRECISION dosing Infliximab
15 Manipulation of Visceral Sensitivity and Immune System in IBS Unknown status NCT00418340 Phase 4 probiotic (bacterial/dietary supplement)
16 Prucalopride Prior to Small Bowel Capsule Endoscopy Unknown status NCT02806206 Phase 4 Prucalopride;Placebo
17 Infliximab for the Prevention of Recurrent Crohn's Disease After Surgery Completed NCT00688636 Phase 4 infliximab;placebo
18 SECOND GENERATION COLON CAPSULE ENDOSCOPY (CCE-2) IN PEDIATRIC CROHN'S DISEASE (CD). Completed NCT02199626 Phase 4
19 Efficacy Study of Pneumococcal Vaccination in Crohn's Disease Completed NCT01505855 Phase 4 23-valent polysaccharide pneumococcal vaccine
20 Rapidity of Response to Adalimumab Treatment in Patients With Crohn´s Disease Completed NCT02148718 Phase 4
21 Diagnostic Accuracy of Capsule Endoscopy in Small Bowel Crohn's Disease Completed NCT00588653 Phase 4
22 Trial of a Treatment Algorithm for the Management of Crohn's Disease Completed NCT01030809 Phase 4
23 A Study Comparing the Acceptability of Pentasa® Sachets Versus Pentasa® Tablets in Children With Crohn´s Disease Completed NCT00225810 Phase 4 Crohn's Disease
24 Study Investigating Tailored Treatment With Infliximab for Active Crohn's Disease Completed NCT01442025 Phase 4 Infliximab;Infliximab;Infliximab
25 The Efficacy of Open Label Infliximab for the Induction and Maintenance of Mucosal Healing in Small Bowel Crohn's Disease Assessed Through Wireless Camera Endoscopy Completed NCT01181765 Phase 4
26 VSL#3 Versus Placebo in Maintenance of Remission in Crohn's Disease Completed NCT00114465 Phase 4 VSL#3
27 Evaluation of the Applicability of the CDEIS to Data Obtained by the Colonic Capsule Endoscopy in Crohn Disease Completed NCT01183845 Phase 4
28 Azithromycin Based Therapy for Induction of Remission in Active Pediatric Crohn's Disease Completed NCT01596894 Phase 4 Azithromycin + Metronidazole;Metronidazole
29 Top Down Versus Step Up Strategies in Crohn's Disease Completed NCT00554710 Phase 4 infliximab+azathioprine;methylprednisolone or budesonide
30 Adalimumab-psoriasis and Small Bowel Lesions Completed NCT01556672 Phase 4 Adalimumab
31 The Effect of Vitamin D3 to Maintain Surgical Remission in Postoperative Crohn's Disease Completed NCT02010762 Phase 4 Vitamin D;Placebo
32 Risedronate Therapy in the Treatment of Low Bone Mineral Density in Crohn's Disease Completed NCT01215890 Phase 4 risedronate;placebo
33 Vitamin D Supplementation in Adult Crohn's Disease Completed NCT01369667 Phase 4
34 Early Immunosuppressants in Crohn's Disease Completed NCT00546546 Phase 4 early immunosuppressants (azathioprine, methotrexate)
35 Endoscopic Detection of Dysplasia in Crohn 's Disease Patient Completed NCT01180452 Phase 4
36 Open Label Natalizumab Safety Extension Study for Subjects With Crohn's Disease Completed NCT00280956 Phase 4 natalizumab
37 Vitamin D in Pediatric Crohn's Disease Completed NCT01187459 Phase 4
38 The Effect of Vitamin K Supplementation on Bone Health in Adult Crohn's Disease Patients Completed NCT01235325 Phase 4
39 Pneumococcal Vaccination of Crohn Patients Completed NCT01947010 Phase 4
40 Immune Modulation by Parenteral Fish Oil in Patients With Crohn's Disease Completed NCT02349594 Phase 4 Omegaven 10%;Intralipid 20%
41 Vitd and Barrier Function in IBD Completed NCT01792388 Phase 4
42 The NOR-SWITCH Study Completed NCT02148640 Phase 4 Innovator infliximab;Biosimilar infliximab
43 Endoscopic Ultrasound (EUS) Guided Treatment With Humira for Crohn's Perianal Fistulas Completed NCT00517296 Phase 4 adalimumab
44 Safety of Accelerated Infliximab Infusions in Patients With Inflammatory Bowel Disease (IBD) Completed NCT01346826 Phase 4 Standard 2 hours-infusion;Accelerated 1 hour-infusion;Accelerated 30 minutes-infusion
45 Centocor Microarray Study of Patients Completed NCT00462072 Phase 4 Infliximab
46 Treatment of Iron Deficiency Anaemia in Inflammatory Bowel Disease With Ferrous Sulphate Completed NCT01991314 Phase 4 Ferrous sulphate
47 Induction of Immunity Against Streptococcus Pneumoniae in Adults With Inflammatory Bowel Disease Completed NCT01908283 Phase 4
48 Immunogenicity of Hepatitis A Vaccine in Inflammatory Bowel Disease (IBD) Patients Completed NCT01341808 Phase 4
49 The Influence of 5–Aminosalicylates on Thiopurine Metabolite Levels Completed NCT00167882 Phase 4 5-aminosalicylate (Pentasa, Ferring)
50 Intestinal Inflammation in Ankylosing Spondylitis and the Effects of Adalimumab on Mucosal Healing Completed NCT01174186 Phase 4 Adalimumab

Search NIH Clinical Center for Ileitis

Cochrane evidence based reviews: ileitis

Genetic Tests for Ileitis

Anatomical Context for Ileitis

The Foundational Model of Anatomy Ontology organs/tissues related to Ileitis:

19
Ileum

MalaCards organs/tissues related to Ileitis:

41
Colon, Bone, T Cells, Small Intestine, Testes, Brain, Liver

Publications for Ileitis

Articles related to Ileitis:

(show top 50) (show all 168)
# Title Authors Year
1
Intestinal Perforation Due to Crohn's Ileitis Immunosuppression Related Lymphoma and Meckel's Diverticulum. ( 29730434 )
2018
2
Acute Terminal Ileitis in Children: A Retrospective Study in Pediatric Emergency Department. ( 29596286 )
2018
3
Endoscopic valvectomy of ileocecal valve stricture resulting in resolution of ileitis in Crohn's disease. ( 29476842 )
2018
4
Incidence and Long-Term Implications of Prepouch Ileitis: An Observational Study. ( 29369899 )
2018
5
Dietary Fiber Pectin Directly Blocks Toll-Like Receptor 2-1 and Prevents Doxorubicin-Induced Ileitis. ( 29545800 )
2018
6
Isolated Terminal Ileitis: When Is It Not Crohn's Disease? ( 29536222 )
2018
7
Microscopic ileitis in diverted and nondiverted enteric segments: an underrecognized condition with a multifactorial etiology. ( 29596895 )
2018
8
Severe Cytomegalovirus ileitis preceded by acute bacterial enteritis in an immunocompetent patient. ( 29562388 )
2018
9
Severe inflammatory ileitis resulting in ileal perforation in association with combination immune checkpoint blockade for metastatic malignant melanoma. ( 29622719 )
2018
10
Histologic features in pediatric ileitis: Is it possible to tip the balance towards Crohn's disease? ( 29397324 )
2018
11
The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn's Disease-Like Ileitis. ( 29554272 )
2018
12
Effective use of ustekinumab for prepouch ileitis without improvement of concomitant pouchitis. ( 29423578 )
2018
13
How do you treat this diversion ileitis and pouchitis? ( 29588334 )
2018
14
Death Receptor 3 Signaling Controls the Balance between Regulatory and Effector Lymphocytes in SAMP1/YitFc Mice with Crohn's Disease-Like Ileitis. ( 29545797 )
2018
15
Histological features of ileitis differentiating pediatric Crohn disease from ulcerative colitis with backwash ileitis. ( 29089273 )
2018
16
Diagnostic Value of Small Bowel Capsule Endoscopy in Isolated Ileitis: A Methodological Mistake. ( 28255834 )
2017
17
Histopathological findings of extra-ileal manifestations at initial diagnosis of Crohn's disease-related ileitis. ( 28108786 )
2017
18
Epicutaneous Tolerance Induction to a Bystander Antigen Abrogates Colitis and Ileitis in Mice. ( 29019858 )
2017
19
Epithelial-specific Toll-like Receptor (TLR)5 Activation Mediates Barrier Dysfunction in Experimental Ileitis. ( 28146004 )
2017
20
Tauroursodeoxycholic acid protects bile acid homeostasis under inflammatory conditions and dampens Crohn's disease-like ileitis. ( 28165466 )
2017
21
Laparoscopic ileocaecal resection versus infliximab for terminal ileitis in Crohn's disease: a randomised controlled, open-label, multicentre trial. ( 28838644 )
2017
22
Foreign body ileitis: a histopathological mimic of Crohn's disease? ( 28689632 )
2017
23
Intestinal, extra-intestinal and systemic sequelae of Toxoplasma gondii induced acute ileitis in mice harboring a human gut microbiota. ( 28414794 )
2017
24
Backwash Is Hogwash: The Clinical Significance of Ileitis in Ulcerative Colitis. ( 28631729 )
2017
25
Prepouch Ileitis After Ileal Pouch-anal Anastomosis: Patterns of Presentation and Risk Factors for Failure of Treatment. ( 29240877 )
2017
26
The Ileitis of Ulcerative Colitis. Why Is It Not Crohn's Disease? ( 28079623 )
2017
27
Yersinia Enterocolitica Ileitis Mimicking Pediatric Crohn's Disease. ( 28230560 )
2017
28
Aspecific ileitis: Crohn's disease or not Crohn's disease? A prospective study. ( 28161731 )
2017
29
Isolated Acute Terminal Ileitis Without Preexisting Inflammatory Bowel Disease Rarely Progresses to Crohn's Disease. ( 29064015 )
2017
30
An unexpected cause of terminal ileitis. ( 27729214 )
2017
31
A rare case of Crohn's ileitis in a patient with constitutional mismatch repair deficiency. ( 28469372 )
2017
32
Chronic ileitis with transmural migration of ingested foreign body treated by laparoscopy. ( 28920530 )
2017
33
A novel model of colitis-associated cancer in SAMP1/YitFc mice with Crohn's disease-like ileitis. ( 28301579 )
2017
34
Fistulating Crohn's terminal ileitis involving sigmoid colon, left salpinx and urinary bladder: a laparoscopic approach - a video vignette. ( 28603931 )
2017
35
Defective ATG16L1-mediated removal of IRE1I+ drives Crohn's disease-like ileitis. ( 28082357 )
2017
36
Post-inflammatory Ileitis Induces Non-neuronal Purinergic Signaling Adjustments of Cholinergic Neurotransmission in the Myenteric Plexus. ( 29167643 )
2017
37
Diagnostic Value of Small Bowel Capsule Endoscopy in Isolated Ileitis: A CAPENTRY Study. ( 27889847 )
2017
38
An Unusual Cause of Granulomatous Ileitis - With a Brief History of the Pathology of Typhoid. ( 29034754 )
2017
39
Acute ileitis facilitates infection with multidrug resistant Pseudomonas aeruginosa in human microbiota-associated mice. ( 28115993 )
2017
40
Uncovering Pathogenic Mechanisms of Inflammatory Bowel Disease Using Mouse Models of Crohn's Disease-Like Ileitis: What is the Right Model? ( 28560286 )
2017
41
Histopathological findings of extra-ileal manifestations at initial diagnosis of Crohn's disease-related ileitis. ( 28424866 )
2017
42
Two Cases of Capecitabine-Induced Ileitis in Patients Treated with Radiochemotherapy to the Pelvis and Review of the Literature. ( 28547118 )
2017
43
Tuberculosis terminal ileitis: A forgotten entity mimicking Crohn's disease. ( 27672643 )
2016
44
Facing Terminal Ileitis: Going Beyond Crohn's Disease. ( 27785317 )
2016
45
Nicotine Inhibits Clostridium difficile Toxin A-Induced Colitis but Not Ileitis in Rats. ( 26881175 )
2016
46
Isolated ileitis associated with primary sclerosing cholangitis in three patients with Crohn's disease. ( 26806276 )
2016
47
Dietary Creatine as a Possible Novel Treatment for Crohn's Ileitis. ( 28008406 )
2016
48
Emergency laparoscopic ileo-colic resection and primary intracorporeal anastomosis for Crohn's acute ileitis with free perforation and faecal peritonitis: first ever reported laparoscopic treatment. ( 26759755 )
2016
49
Genetic deletion of the bacterial sensor NOD2 improves murine Crohn's disease-like ileitis independent of functional dysbiosis. ( 27848951 )
2016
50
Visceral pain triggered by traction on the ileocecal ligament with ileitis. ( 27757049 )
2016

Variations for Ileitis

Expression for Ileitis

Search GEO for disease gene expression data for Ileitis.

Pathways for Ileitis

Pathways related to Ileitis according to GeneCards Suite gene sharing:

(show all 48)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.92 CSF2 IL17A IL6 MPO NOD2 TLR2
2
Show member pathways
13.3 CCR3 CSF2 IL17A IL6 TLR2 TLR4
3
Show member pathways
12.93 IL6 NOD2 TLR2 TLR4 TLR5 TNF
4
Show member pathways
12.63 IL6 TLR2 TLR4 TLR5 TNF
5
Show member pathways
12.56 CSF2 IL17A IL6 TNF
6
Show member pathways
12.51 IL17A IL6 MPO TNF
7 12.48 IL17A MPO TLR2 TNF
8
Show member pathways
12.45 TLR2 TLR4 TLR5 TNF
9
Show member pathways
12.43 CCR3 CSF2 IL6 TLR2 TLR4 TNF
10
Show member pathways
12.36 CSF2 IL17A IL6 TNF
11
Show member pathways
12.21 IL6 TLR2 TLR4 TLR5 TNF
12
Show member pathways
12.18 IL6 TLR4 TNF
13
Show member pathways
12.17 IL6 TLR2 TLR5 TNF
14 12.16 IL6 NOD2 TLR2 TLR4 TNF
15
Show member pathways
12.13 CSF2 IL17A IL6 TLR2 TLR5 TNF
16
Show member pathways
12.11 IL6 TLR2 TLR4 TLR5 TNF
17 12.09 IL6 TLR2 TLR4 TLR5 TNF
18 12.05 MPO TLR2 TLR4
19
Show member pathways
12.01 IL17A IL6 TLR2 TLR4 TLR5 TNF
20
Show member pathways
11.96 TLR2 TLR4 TLR5
21 11.94 IL6 TLR4 TNF
22
Show member pathways
11.92 IL17A IL6 NOD2 TLR2 TLR4 TLR5
23 11.91 IL17A IL6 TNF
24 11.91 CSF2 IL6 NOD2 TNF
25 11.87 CCR3 CSF2 IL6 MPO TNF
26
Show member pathways
11.84 CSF2 IL17A IL6 TLR4
27 11.83 CSF2 IL6 TNF
28 11.79 CSF2 IL6 TLR4 TLR5
29 11.76 TLR2 TLR4 TLR5
30 11.75 CSF2 IL6 TLR2 TLR4 TNF
31 11.71 IL6 TLR4 TNF
32 11.69 CSF2 IL6 TNF
33
Show member pathways
11.62 CSF2 IL6 TNF
34 11.62 CCR3 CSF2 IL6 TNF
35 11.5 CSF2 IL6 TNF
36 11.49 IL6 MPO TNF
37 11.49 TLR2 TLR4 TNF
38 11.45 IL6 TLR2 TLR4 TNF
39 11.33 IL6 TLR4 TNF
40 11.29 IL6 TLR2 TLR4 TLR5 TNF
41 11.27 IL17A IL6 TNF
42 11.24 CSF2 IL6 TNF
43 11.1 CCR3 TLR2
44 11.06 NOD2 TNF
45 11.05 CSF2 IL17A IL6 TLR2 TLR4 TNF
46 11.04 IL6 TNF
47 10.97 IL6 TNF
48 10.89 MPO TNF

GO Terms for Ileitis

Biological processes related to Ileitis according to GeneCards Suite gene sharing:

(show all 41)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.99 CSF2 IL17A IL6 TLR2 TLR4 TNF
2 regulation of signaling receptor activity GO:0010469 9.98 CSF2 IL17A IL6 TNF
3 positive regulation of gene expression GO:0010628 9.96 CSF2 IL6 TLR2 TLR4 TNF
4 cytokine-mediated signaling pathway GO:0019221 9.94 CSF2 IL17A IL6 TNF
5 defense response to bacterium GO:0042742 9.88 MPO NOD2 TLR4 TLR5 TNF
6 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.86 NOD2 TLR4 TNF
7 defense response GO:0006952 9.85 MPO NOD2 TNF
8 activation of MAPK activity GO:0000187 9.84 NOD2 TLR4 TNF
9 defense response to Gram-positive bacterium GO:0050830 9.83 IL6 TLR2 TNF
10 regulation of inflammatory response GO:0050727 9.8 NOD2 TLR4 TNF
11 positive regulation of JNK cascade GO:0046330 9.78 NOD2 TLR4 TNF
12 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.77 IL6 NOD2 TLR2 TLR4 TNF
13 positive regulation of tumor necrosis factor production GO:0032760 9.76 NOD2 TLR2 TLR4
14 positive regulation of nitric oxide biosynthetic process GO:0045429 9.75 TLR4 TLR5 TNF
15 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.72 TLR2 TLR4 TLR5
16 cellular response to lipopolysaccharide GO:0071222 9.72 CSF2 IL6 TLR4 TLR5 TNF
17 lipopolysaccharide-mediated signaling pathway GO:0031663 9.71 TLR2 TLR4 TNF
18 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.71 NOD2 TLR2 TLR4 TNF
19 positive regulation of interleukin-10 production GO:0032733 9.7 NOD2 TLR2 TLR4
20 positive regulation of interferon-beta production GO:0032728 9.68 TLR2 TLR4
21 positive regulation of interleukin-12 production GO:0032735 9.68 TLR2 TLR4
22 positive regulation of osteoclast differentiation GO:0045672 9.67 IL17A TNF
23 positive regulation of stress-activated MAPK cascade GO:0032874 9.67 NOD2 TLR4
24 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.67 IL17A NOD2 TLR4
25 negative regulation of growth of symbiont in host GO:0044130 9.66 MPO TNF
26 I-kappaB phosphorylation GO:0007252 9.65 TLR2 TLR4
27 positive regulation of podosome assembly GO:0071803 9.65 CSF2 TNF
28 cellular response to lipoteichoic acid GO:0071223 9.64 TLR2 TLR4
29 macrophage activation GO:0042116 9.63 CSF2 TLR4
30 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.63 NOD2 TLR2 TLR4
31 negative regulation of lipid storage GO:0010888 9.62 IL6 TNF
32 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.61 TLR4 TNF
33 regulation of cytokine secretion GO:0050707 9.61 TLR2 TLR4 TLR5
34 positive regulation of interleukin-23 production GO:0032747 9.6 CSF2 IL17A
35 positive regulation of toll-like receptor signaling pathway GO:0034123 9.59 TLR2 TLR5
36 cytokine secretion involved in immune response GO:0002374 9.57 NOD2 TLR2
37 positive regulation of chemokine production GO:0032722 9.56 IL6 TLR2 TLR4 TNF
38 inflammatory response GO:0006954 9.56 CCR3 IL17A IL6 NOD2 TLR2 TLR4
39 positive regulation of interleukin-6 production GO:0032755 9.55 IL6 NOD2 TLR2 TLR4 TNF
40 positive regulation of interleukin-8 production GO:0032757 9.02 NOD2 TLR2 TLR4 TLR5 TNF
41 positive regulation of transcription by RNA polymerase II GO:0045944 10.09 IL17A IL6 NOD2 TLR2 TLR4 TNF

Molecular functions related to Ileitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.26 CSF2 IL17A IL6 TNF
2 peptidoglycan binding GO:0042834 9.16 NOD2 TLR2
3 lipopolysaccharide receptor activity GO:0001875 8.62 TLR2 TLR4

Sources for Ileitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI