MCID: ILM001
MIFTS: 39

Ileum Cancer

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Ileum Cancer

MalaCards integrated aliases for Ileum Cancer:

Name: Ileum Cancer 12 15
Ileal Neoplasms 44 73
Ileal Neoplasm 12 15
Malignant Neoplasm of Ileum 12
Ileal Cancer 73
Ileal Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10153 DOID:10156
ICD10 33 C17.2
ICD9CM 35 152.2
SNOMED-CT 68 93832004
MeSH 44 D007078
NCIt 50 C3130

Summaries for Ileum Cancer

Disease Ontology : 12 A small intestine cancer that is located in the ileum.

MalaCards based summary : Ileum Cancer, also known as ileal neoplasms, is related to cystic teratoma and teratoma. An important gene associated with Ileum Cancer is ERBIN (Erbb2 Interacting Protein), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Lymphoid Cell Differentiation Pathways. The drugs Liver Extracts and Cola have been mentioned in the context of this disorder. Affiliated tissues include small intestine, lung and ovary, and related phenotypes are immune system and digestive/alimentary

Related Diseases for Ileum Cancer

Diseases related to Ileum Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 122)
# Related Disease Score Top Affiliating Genes
1 cystic teratoma 29.7 KRT7 GFAP ENO2
2 teratoma 29.7 KRT7 GFAP ENO2
3 type c thymoma 10.3 SST CD5
4 lymphomatoid granulomatosis 10.3 TIA1 GZMB
5 lichen sclerosus et atrophicus 10.3 TIA1 GZMB
6 viral esophagitis 10.3 TIA1 GZMB
7 tracheal lymphoma 10.3 CD5 MME
8 lymphocytic gastritis 10.3 TIA1 GZMB
9 encapsulated thymoma 10.2 SST MME
10 intravascular large b-cell lymphoma 10.2 MME CD5
11 primary cutaneous anaplastic large cell lymphoma 10.2 TIA1 GZMB
12 large cell acanthoma 10.2 KRT7 KRT10
13 mongolian spot 10.2 SST ENO2
14 lethal midline granuloma 10.2 TIA1 NCAM1
15 intracranial cysts 10.2 GFAP ENO2
16 balloon cell malignant melanoma 10.2 MME KRT7
17 retroperitoneal neuroblastoma 10.2 SST ENO2
18 pancreatic somatostatinoma 10.2 SST ENO2
19 duodenal somatostatinoma 10.2 SST ENO2
20 composite lymphoma 10.2 TIA1 GZMB CD5
21 primitive neuroectodermal tumor of the cervix uteri 10.2 GFAP ENO2
22 nodular hidradenoma 10.2 KRT10 KRT7
23 melanotic medulloblastoma 10.2 GFAP ENO2
24 parachordoma 10.2 KRT7 GFAP
25 b-cell expansion with nfkb and t-cell anergy 10.2 CD5 GZMB TIA1
26 papillary transitional carcinoma 10.2 KRT7 ENO2
27 small cell carcinoma of the bladder 10.2 KRT7 ENO2
28 gastric leiomyosarcoma 10.2 PDGFRA ENO2
29 middle ear adenoma 10.2 KRT7 ENO2
30 clear cell papillary renal cell carcinoma 10.2 MME KRT7
31 rhinosporidiosis 10.2 TIA1 NCAM1
32 parasitic ichthyosporea infectious disease 10.2 TIA1 NCAM1
33 sensory organ benign neoplasm 10.2 KRT7 ENO2
34 multiple mucosal neuroma 10.2 ENO2 NCAM1
35 lung meningioma 10.2 NCAM1 ENO2
36 choriocarcinoma of the testis 10.2 TIA1 KRT7 GZMB
37 mixed glioma 10.2 GFAP PDGFRA
38 cerebellar medulloblastoma 10.2 GFAP ENO2
39 renal adenoma 10.2 NCAM1 KRT7
40 gastrointestinal neuroendocrine benign tumor 10.2 SST GAST
41 pylorospasm 10.2 SST GAST
42 gallbladder small cell carcinoma 10.2 NCAM1 ENO2
43 choriocarcinoma of ovary 10.2 NCAM1 ENO2
44 central nervous system primitive neuroectodermal neoplasm 10.2 ENO2 GFAP
45 cutaneous ganglioneuroma 10.2 NCAM1 ENO2
46 gastric neuroendocrine neoplasm 10.2 SST GAST
47 mucinous tubular and spindle renal cell carcinoma 10.2 MME KRT7 KRT10
48 angioimmunoblastic t-cell lymphoma 10.2 GZMB MME TIA1
49 bladder lymphoma 10.2 MME KRT7 CD5
50 eccrine sweat gland neoplasm 10.2 MME KRT7 KRT10

Graphical network of the top 20 diseases related to Ileum Cancer:



Diseases related to Ileum Cancer

Symptoms & Phenotypes for Ileum Cancer

MGI Mouse Phenotypes related to Ileum Cancer:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 10.03 CD5 CTSB GAST GFAP ID2 MME
2 digestive/alimentary MP:0005381 9.92 CTSB GAST GFAP ID2 PDGFRA SOCS1
3 integument MP:0010771 9.76 CD5 CTSB ERBIN ID2 MME PDGFRA
4 neoplasm MP:0002006 9.43 CTSB GAST ID2 PDGFRA SOCS1 TLR4
5 normal MP:0002873 9.23 CD5 CTSB GFAP ID2 PDGFRA SOCS1

Drugs & Therapeutics for Ileum Cancer

Drugs for Ileum Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Liver Extracts Phase 1
2 Cola Phase 1
3 Fluorodeoxyglucose F18
4 Immunoglobulins
5 Antibodies

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study of TCM Syndrome of Hepatocellular Carcinoma and Colorectal Cancer Based on System Science Recruiting NCT03189992 Phase 1 Bushen-Jianpi Dedoction;cinobufotalin injection
2 Defining PET / CT Protocols With Optimized F18-FDG (Fluorodeoxyglucose) Dose, Focusing on Reduced Radiation Dose and Improved Image Quality Completed NCT02378337
3 Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer Terminated NCT00899132

Search NIH Clinical Center for Ileum Cancer

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: ileal neoplasms

Genetic Tests for Ileum Cancer

Anatomical Context for Ileum Cancer

MalaCards organs/tissues related to Ileum Cancer:

41
Small Intestine, Lung, Ovary, Testis, T Cells, B Cells, Thymus

The Foundational Model of Anatomy Ontology organs/tissues related to Ileum Cancer:

19
The Ileum

Publications for Ileum Cancer

Articles related to Ileum Cancer:

# Title Authors Year
1
Spindle cell tumour with glandular elements: an unusual ileal neoplasm. ( 19474356 )
2009
2
Recurrent lower gastrointestinal hemorrhage: ileal neoplasm diagnosed by scintigraphy with Tc 99m red blood cells and angiography. ( 8969358 )
1996

Variations for Ileum Cancer

Expression for Ileum Cancer

Search GEO for disease gene expression data for Ileum Cancer.

Pathways for Ileum Cancer

GO Terms for Ileum Cancer

Cellular components related to Ileum Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.47 CALD1 ENO2 ERBIN GFAP GZMB ID2

Biological processes related to Ileum Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 embryonic digestive tract morphogenesis GO:0048557 9.16 ID2 PDGFRA
2 astrocyte development GO:0014002 8.96 GFAP TLR4
3 regulation of cytokine secretion GO:0050707 8.62 SOCS1 TLR4

Molecular functions related to Ileum Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.55 ACAP1 CALD1 CD5 CTSB ENO2 ERBIN

Sources for Ileum Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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