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ILEUS
MCID: ILS001
MIFTS: 51

Ileus (ILEUS)

Categories: Gastrointestinal diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Ileus

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MalaCards integrated aliases for Ileus:

Name: Ileus 12 43 15
Ileus of Intestine 12

Classifications:

MalaCards categories:
Anatomical: Gastrointestinal diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:8440
MeSH 43 D045823
NCIt 49 C37979
SNOMED-CT 67 81060008
ICD10 32 K56.7
UMLS 71 C1258215
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Summaries for Ileus

About this section
MalaCards based summary : Ileus, also known as ileus of intestine, is related to meconium ileus and paralytic ileus. An important gene associated with Ileus is GUCY2C (Guanylate Cyclase 2C), and among its related pathways/superpathways are Signaling by GPCR and Peptide ligand-binding receptors. The drugs Peppermint and Atracurium have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and liver, and related phenotypes are homeostasis/metabolism and behavior/neurological

Wikipedia : 74 Ileus is a disruption of the normal propulsive ability of the intestine due to the malfunction of... more...

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Related Diseases for Ileus

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Diseases related to Ileus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 905)
# Related Disease Score Top Affiliating Genes
1 meconium ileus 34.8 SLC9A3 SLC6A14 SLC26A9 GUCY2C CFTR
2 paralytic ileus 34.6 OPRM1 MLN F2 CRP
3 volvulus of midgut 32.3 GUCY2C F2 CRP
4 cystic fibrosis 32.1 VIP TNF SLC9A3 SLC26A9 INS IL6
5 intussusception 32.1 VIP IL6 CRP CFTR
6 cholelithiasis 31.5 SST INS CRP CCK
7 intestinal obstruction 31.3 SST SLC26A9 MLN IL6 GUCY2C GHRL
8 peritonitis 31.3 TNF IL6 IL10 F2 CRP
9 diverticulitis 31.3 TNF IL6 CRP
10 pain agnosia 31.2 OPRM1 IL6 CCK CALCA
11 appendicitis 31.1 TNF IL6 IL10 CRP
12 constipation 31.1 VIP SST OPRM1 MLN CCK CALCA
13 crohn's disease 31.1 TNF IL6 IL10 CRP
14 pneumatosis cystoides intestinalis 31.1 MLN CRP
15 colonic pseudo-obstruction 31.0 VIP SST MLN
16 choledocholithiasis 30.8 F2 CRP CCK
17 vipoma 30.6 VIP SST CALCA
18 ulcerative colitis 30.6 TNF IL6 IL10 CRP
19 obstructive jaundice 30.5 TNF IL6 F2 CRP
20 aortitis 30.5 TNF IL6 CRP
21 herpes zoster 30.5 TNF IL10 CRP
22 ileitis 30.5 TNF IL6 IL10
23 gastroparesis 30.5 SST MLN GHSR GHRL CCK
24 active peptic ulcer disease 30.5 SST F2 CRP
25 amyloidosis 30.4 TNF INS IL6 CRP
26 perinatal necrotizing enterocolitis 30.4 TNF IL6 IL10 CRP
27 aspiration pneumonia 30.4 INS IL6 F2 CRP
28 exocrine pancreatic insufficiency 30.4 TNF CFTR CCK
29 abdominal tuberculosis 30.4 TNF F2 CRP
30 toxic shock syndrome 30.4 TNF IL6 IL10 CRP
31 compartment syndrome 30.4 TNF IL6 F2 CRP
32 peptic ulcer disease 30.4 TNF SST IL10 GHRL
33 lymphadenitis 30.3 TNF IL10 CRP
34 gastroenteritis 30.3 TNF MLN IL6 IL10 CRP CALCA
35 gastric ulcer 30.3 TNF SST IL6 CALCA
36 pancreatitis 30.3 TNF SST INS IL6 CRP CFTR
37 echinococcosis 30.3 TNF IL6 IL10
38 pulmonary tuberculosis 30.3 TNF IL6 IL10 CRP
39 emphysematous cholecystitis 30.3 F2 CRP
40 congestive heart failure 30.3 TNF INS IL6 CRP
41 pheochromocytoma 30.2 VIP TNF SST MLN IL6 CRH
42 cholangitis, primary sclerosing 30.2 TNF IL6 F2 CFTR
43 short bowel syndrome 30.2 SST SLC9A3 IL6 GHRL CCK
44 exudative vitreoretinopathy 1 30.2 TNF INS IL6 CRP
45 cholangitis 30.2 TNF SST IL6 IL10 F2 CRP
46 pulmonary edema 30.2 TNF IL10 F2 CRP CFTR
47 duodenitis 30.2 INS CRP CCK
48 intermediate coronary syndrome 30.2 INS IL6 CRP
49 respiratory failure 30.2 TNF IL6 IL10 F2 CRP CFTR
50 hypothyroidism 30.1 TNF SST INS GHRL F2 CRP

Graphical network of the top 20 diseases related to Ileus:



Diseases related to Ileus
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Symptoms & Phenotypes for Ileus

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MGI Mouse Phenotypes related to Ileus:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.3 CCK CFTR CRH CRP F2 GHRL
2 behavior/neurological MP:0005386 10.27 CFTR CRH F2 GHRL GHSR GUCY2C
3 digestive/alimentary MP:0005381 10.25 CFTR F2 GHRL GHSR GUCY2C IL10
4 endocrine/exocrine gland MP:0005379 10.22 CCK CFTR CRH GHRL IL10 IL6
5 adipose tissue MP:0005375 10.13 CRH GHRL GHSR GUCY2C IL6 INS
6 immune system MP:0005387 10.13 CFTR CRH CRP F2 GUCY2C IL10
7 integument MP:0010771 9.91 CRH F2 GUCY2C IL10 IL6 INS
8 no phenotypic analysis MP:0003012 9.81 CCK CFTR CRH GHSR IL10 INS
9 normal MP:0002873 9.65 CFTR CRH F2 GHRL IL10 INS
10 reproductive system MP:0005389 9.32 CFTR F2 IL10 IL6 INS OPRM1
Sources

Drugs & Therapeutics for Ileus

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Drugs for Ileus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 291)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Peppermint Approved Phase 4
2
Atracurium Approved, Experimental, Investigational Phase 4 64228-79-1 47319
3
Orphenadrine Approved Phase 4 83-98-7 4601
4
Histamine Approved, Investigational Phase 4 51-45-6 774
5
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
6
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
7
Thiopental Approved, Vet_approved Phase 4 76-75-5 3000715
8
Povidone-iodine Approved Phase 4 25655-41-8
9
Succinylcholine Approved Phase 4 306-40-1 5314
10
Magnesium hydroxide Approved, Investigational Phase 4 1309-42-8
11
Bisacodyl Approved Phase 4 603-50-9
12
Bismuth subsalicylate Approved, Vet_approved Phase 4 14882-18-9 53629521
13
Loperamide Approved Phase 4 53179-11-6 3955
14
Dimenhydrinate Approved Phase 4 523-87-5 441281
15
Simethicone Approved Phase 4 8050-81-5
16
Sorbitol Approved Phase 4 50-70-4 5780
17
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
18
tannic acid Approved Phase 4 1401-55-4
19
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
20
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
21
Clonidine Approved Phase 4 4205-90-7 2803
22
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
23
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
24
Labetalol Approved Phase 4 36894-69-6 3869
25 Hydrotalcite Approved, Experimental, Investigational Phase 4 12304-65-3
26
Aluminum hydroxide Approved, Investigational Phase 4 21645-51-2
27
Sucralfate Approved Phase 4 54182-58-0
28
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
29
Naloxone Approved, Vet_approved Phase 4 465-65-6 5284596
30
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
31
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
32
Remifentanil Approved Phase 4 132875-61-7 60815
33
Ondansetron Approved Phase 4 99614-02-5 4595
34
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
35
Scopolamine Approved, Investigational Phase 4 51-34-3, 6533-68-2 5184
36
Cyclobenzaprine Approved Phase 4 303-53-7 2895
37
Pregabalin Approved, Investigational Phase 4 148553-50-8 5486971
38
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
39
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
40
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
41
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
42
Tapentadol Approved Phase 4 175591-23-8 9838022
43
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
44
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
45
Morphine Approved, Investigational Phase 4 57-27-2 5288826
46
Nicotine Approved Phase 4 54-11-5 942 89594
47
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
48
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
49
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
50
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826

Interventional clinical trials:

(show top 50) (show all 379)
# Name Status NCT ID Phase Drugs
1 Anti-inflammatory Effect of Pre-operative Stimulation of the Cholinergic Anti-Inflammatory Pathway: A Potential New Therapeutical Intervention for Postoperative Ileus Unknown status NCT02425774 Phase 4 Prucalopride;Placebo
2 Influence of Gum Chewing on Postoperative Bowel Activity After Complete Staging Surgery for Gynecological Malignancies Unknown status NCT01835119 Phase 4 gum
3 Effect of Mosapride on Postoperative Ileus in Patients Undergoing Colorectal Surgery Unknown status NCT02056405 Phase 4 Mosapride;Placebo
4 Effect of Intravenous Lidocaine on Postoperative Pain Management After Laparoscopy Cholecystectomy Unknown status NCT02997215 Phase 4 Lidocaine;Saline Placebo
5 Usefulness Of Flospan As A Premedication For Colonoscopy : A Randomized Double Blind Controlled Trial Unknown status NCT01842932 Phase 4 Phloroglucin;Cimetropium bromide;Placebo
6 Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery as Part of an Enhanced Recovery After Surgery Protocol: A Randomized Prospective Single- Center Trial. Unknown status NCT02958566 Phase 4 Acetaminophen;Gabapentin;Orphenadrine;Lidocaine;Marcaine;Ketamine;Methadone;Tramadol;Ketorolac;Morphine Sulfate;Fentanyl;Dilaudid;Hydrocodone-Acetaminophen Tab 5-325 MG;Morphine Sulfate;Fentanyl;Dilaudid;HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET
7 Comparative Randomized Controlled Trial Study of General Balanced Anesthesia Based on Opioid and Opioid Sparing Balanced Anesthesia for Cholecystectomy Surgery Via Laparoscopy: Intraoperative and Postoperative Outcomes Unknown status NCT02953210 Phase 4 dexter ketamine;Lidocaine Hydrochloride;Fentanyl Hydrochloride;Clonidine Hydrochloride;Midazolam Hydrochloride;Isoflurane Volatile Liquid;Rocuronium Injectable Solution;Propofol 1 % Injectable Suspension;Dexamethasone-21-Sulfobenzoate, Sodium Salt;Ranitidine Hydrochloride;Ondansetron Hydrochloride;Ketorolac Injectable Solution;Bupivacaine Hydrochloride
8 NK Activity Modulation by Intravenous Lidocaine During Laparoscopic Colorectal Surgery Unknown status NCT01841294 Phase 4 Intravenous Lidocaine;Normal saline infusion
9 Randomised Study to Compare the Regain of Gastrointestinal Motility After General Anaesthesia Versus Spinal Anaesthesia in Caesarean Section.Kasr El Ainy,Egypt Experience Unknown status NCT02504749 Phase 4
10 Chronic Significant Pain and Functional Outcome After Laparoscopic Versus Open Groin Hernia Mesh Repair: Design of a Randomized Controlled Clinical Trial Unknown status NCT00625534 Phase 4
11 COLITIS: Clostridial Infection and Oral Lavage -Improving Treatment Before Illness Becomes Severe Unknown status NCT01630096 Phase 4 Nu-Lytely
12 Prospective Randomized Double Blind Study of the Effect of Gastrografin on Postoperative Ileus After Colorectal Surgery Completed NCT01440712 Phase 4 Gastrografin;physiological serum
13 A Phase 4, Multicenter, Double-Blind, Placebo-Controlled, Parallel Study of Alvimopan for the Management of Postoperative Ileus in Subjects Undergoing Radical Cystectomy. Completed NCT00708201 Phase 4 Alvimopan;Placebo
14 A New Approach of Neostigmine in Unavoidable Post Operative Ileus After Surgery Completed NCT00676377 Phase 4 Neostigmine;Saline
15 A Randomized Controlled Trial of the Effect of Simethicone on Postoperative Ileus in Patients Undergoing Colorectal Surgery: A Pilot Study Completed NCT02161367 Phase 4 Simethicone;Oral Suspending Vehicle
16 Effect of Postoperative Laxative on Bowel Function After Colonic Surgery Completed NCT00427492 Phase 4 Magnesia;Placebo
17 Preoperative Bowel Preparation Versus no Preparation Before Spinal Surgery: a Randomised Clinical Trial Completed NCT01879605 Phase 4 Docusate natrium and sorbitol;Bisacodyl
18 Randomized Clinical Trial of Bisacodyl Versus Placebo on Postoperative Bowel Motility in Elective Colorectal Surgery Completed NCT00509327 Phase 4 bisacodyl;glucosemonohydricum
19 Influence of Epidural Analgesia in Elective Laparoscopic Colorectal Resections Completed NCT00512395 Phase 4 epidural analgesia (Duracain/Fentanyl/Naropin)
20 Opioid Free Anesthesia: What About Patient Comfort? Completed NCT02882035 Phase 4
21 Impact of Oral Application of Gastrografin on the Meconium Evacuation in Very Low Birth Weight Infants- a Phase 4 Study Completed NCT01515696 Phase 4 Gastrografin;Sterile water
22 Postoperative Analgesic Effects of Dexmedetomidine Added to Bupivacaine for Transversus Abdominis Plane Block for Lower Abdominal Surgery Completed NCT02064530 Phase 4 Bupivacaine;Dexmedetomidine;serum physiologic
23 Laparoscopic Versus Open Sigmoid Colectomy for Diverticular Disease: A Prospective Randomized Single-Blind Trial Completed NCT00453830 Phase 4
24 Effect of Endovenous Lidocaine on Analgesia and Serum Cytokines Concentration: Randomized and Double-blind Trial Completed NCT02363699 Phase 4 Lidocaine;Saline solution
25 The Impact of Visceral Osteopathic Treatment on the Meconium Evacuation in Very Low Birth Weight Infants Completed NCT02140710 Phase 4
26 Laparoscope Subtotal Colectomy With Anti-peristaltic Ileo-sigmoid Anastomosis for the Treatment of Slow-transit Constipation:Therapeutic Evaluation Completed NCT02147574 Phase 4
27 Surgical Pain Control With Ropivacaine by Atomized Delivery Completed NCT01480089 Phase 4 Intraperitoneal Ropivacaine (AIR);Atomized Intraperitoneal Saline (AIS)
28 A Randomized Clinical Study of the Efficacy of a Formulation of Four Probiotics for the Prevention of Post-operative Complications in Patients Undergoing Colorectal Surgery Completed NCT02313519 Phase 4
29 Estimation of the Effect of Intravenous Lidocaine on BIS-guided Propofol Requirements During General Anesthesia Completed NCT01366300 Phase 4 Intravenous lidocaine infusion;Propofol 1% (intravenous infusion)
30 Randomized, Double-Blinded, Active-Controlled Study to Evaluate the Intraoperative Use of Labetalol vs. Esmolol for Maintaining Hemodynamic Stability During Laparoscopic Surgery: Effect on Recovery and Postoperative Pain Completed NCT01114971 Phase 4 Fentanyl;Labetalol;Esmolol
31 Impact of the Serratus Plane Block in Pain and the Use of Opioids in Breast Completed NCT02905149 Phase 4
32 A Comparison of Effectiveness of Oral Sucrolfate, Alginate and Hydrotalcide in Dispeptic Pain Treatment: Randomized Trial Completed NCT03635372 Phase 4 Alginate;Sucralfate;Hydrotalcite
33 A Randomized Comparison of Concomitant Incontinence Procedures Performed With Abdominal Sacral Colpopexy: the Burch Versus Mid-urethral Sling Trial Completed NCT00934999 Phase 4
34 Use of Nitrous Oxide for Analgesia During Colonoscopy - A Randomised Trial Completed NCT00318825 Phase 4 Nitrous oxide
35 Cost- Effectiveness and Cost-utility of Laparoscopic Versus Open Repair of Ventral Hernia: Randomized Clinical Trial Completed NCT01778387 Phase 4
36 A Simple Oral Nutrition Protocol Reduces Length of Stay in Patients With Regular Radical Cystectomy Completed NCT01777126 Phase 4
37 Effect of Perioperative Intravenous Lidocaine on Opioid Consumption and Pain After Laparoscopic Totally Extraperitoneal Inguinal Hernioplasty Completed NCT02601651 Phase 4 Lidocaine;Normal saline
38 Assessing the Safety of a Continuous Potassium Chloride Infusion in Critical Care: A Randomised Controlled Trial Completed NCT00718068 Phase 4 Sterile Potassium Chloride Concentrate;Sterile Potassium Chloride Concentrate
39 Adjuvant Analgesic Effects of Low Dose Tramadol/Acetaminophen Combination After Open Gynaecological Surgery Completed NCT00942565 Phase 4 tramadol/acetaminophen;acetaminophen
40 Non Operative Treatment for Acute Appendicitis: Study on Efficacy and Safety of Antibiotic Treatment (Amoxicillin and Clavulanic Acid) in Patients With Right Sided Lower Abdominal Pain Completed NCT01096927 Phase 4 Amoxicillin and Clavulanic Acid
41 PEG-Electrolyte Solution (FORTRANS®) With Mentholyptus Drops (Halls®) Versus Reduced Volume Ascorbic Acid Supplemented PEG-Electrolyte (MoviPrep®) in Colonoscopy Preparation: A Randomised Controlled Study Completed NCT01788709 Phase 4
42 A Double Blind, Randomized, Parallel Design Study to Evaluate the Effectiveness of Post-operative Dose of Alvimopan(Entereg) in Preventing Post-operative Ileus in Poly-traumatized Patients Recruiting NCT03068975 Phase 4 Alvimopan;Placebo
43 The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus Recruiting NCT03176316 Phase 4 Naloxone
44 Efficacy of the Liposomal Bupivacaine for Postoperative Pain Control in Urologic Procedures Recruiting NCT02805504 Phase 4 Exparel;Marcaine
45 Impact of the Administration of Intravenous or Paravertebral Lidocaine in Continuous Perfusion During the Intraoperative Period of Lung Resection Surgery on the Appearance of Postoperative Complications Recruiting NCT03905837 Phase 4 Lidocaine;Remifentanil
46 Multimodal Analgesia vs. Routine Care Pain Management for Lumbar Spine Fusion Surgery: A Prospective Randomized Study Recruiting NCT02202369 Phase 4
47 The Use of Gastrografin to Help Alleviate Bowel Obstruction Related to Poor Bowel Motility in Gastroschisis Patients. Recruiting NCT03334578 Phase 4 Gastrografin
48 A Prospective, Double-blind, Randomized, and Controlled Clinical Trial to Compare the Effectiveness of Intravenous Bezlotoxumab (10 mg/kg) Versus Placebo in Decreasing Morbidity and Mortality in Patients With Fulminant Clostridioides Difficile Requiring Surgical Intervention. Recruiting NCT03756454 Phase 4
49 A Prospective, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial Evaluating the Use of Perioperative Intravenous Lidocaine Infusion to Decrease Pain Scores and Opioid Consumption After Robotic-Assisted Prostatectomy and Robotic-Assisted Partial Nephrectomy Recruiting NCT03824808 Phase 4 Lidocaine Hydrochloride 0.8% in Dextrose 5% Solution;0.9% Sodium Chloride Injection
50 The Impact of the Continuous Infusion of Intraperitoneal Analgesics on Postoperative Pain After Minimally Invasive Hysterectomy: a Randomized Controlled Trial Recruiting NCT04130464 Phase 4 Ropivacaine Infusion from ON-Q Pump;Ropivacaine + Ketorolac Infusion from ON-Q Pump;Normal Saline Infusion from ON-Q Pump

Search NIH Clinical Center for Ileus

Cochrane evidence based reviews: ileus

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Genetic Tests for Ileus

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Anatomical Context for Ileus

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MalaCards organs/tissues related to Ileus:

40
Colon, Small Intestine, Liver, Lung, Kidney, Heart, Pancreas
Sources

Publications for Ileus

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Articles related to Ileus:

(show top 50) (show all 11355)
# Title Authors PMID Year
1
A new zinc chelator, IPZ-010 ameliorates postoperative ileus. 61
31862476 2020
2
When is parenteral nutrition indicated in the hospitalized, acutely ill patient? 61
31895227 2020
3
Colectomy with ileostomy for severe ulcerative colitis-postoperative complications and risk factors. 61
31865435 2020
4
Functional outcomes after laparoscopic versus robotic-assisted rectal resection: a systematic review and meta-analysis. 61
32025924 2020
5
Cystic fibrosis in Turkey: First data from the national registry. 61
31710166 2020
6
Cystic fibrosis newborn screening in Denmark: Experience from the first 2 years. 61
31682332 2020
7
Outcomes of Open Complex Ventral Hernia Repairs With Retromuscular Placement of Poly-4-Hydroxybutyrate Bioabsorbable Mesh. 61
31617453 2020
8
Prognostic relevance of pre- and postoperative plasma l-lactate measurements in calves with acute abdominal emergencies. 61
31759607 2020
9
Clostridioides difficile Infection: Update on Management. 61
32003951 2020
10
Author response to: Comment on: Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery. 61
31971620 2020
11
Comment on: Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery. 61
31971625 2020
12
[Gallstone ileus as a cause of abdominal pain in the elderly patient]. 61
32035787 2020
13
The effects of ulimorelin, a ghrelin agonist, on liquid gastric emptying and colonic transit in humans. 61
32017341 2020
14
Impact of Preoperative Care for Rectal Adenocarcinoma on Pathologic Specimen Quality and Postoperative Morbidity: A NSQIP Analysis. 61
31672638 2020
15
Laceration of the transverse mesocolon in an old man with a habit of abdominal massage for constipation: a case report. 61
31898753 2020
16
Pre-Operative, Intra-Operative, and Post-Operative Factors Associated with Post-Discharge Venous Thromboembolism Following Colorectal Cancer Resection. 61
31420856 2020
17
American Gastroenterological Association Clinical Practice Update: Management of Pancreatic Necrosis. 61
31479658 2020
18
Ileocolic invagination in adults: A totally minimally invasive endoscopic and laparoscopic staged approach. 61
30777993 2020
19
Mesocolic hernia after laparoscopic transverse colectomy: A case report. 61
31838433 2020
20
Surgical Safety of Radical Cystectomy and Pelvic Lymph Node Dissection Following Neoadjuvant Pembrolizumab in Patients with Bladder Cancer: Prospective Assessment of Perioperative Outcomes from the PURE-01 Trial. 61
31911010 2020
21
A case of ileus surgery using the water pressure method against ileus caused by incarceration into the inverted bladder diverticulum. 61
31919696 2020
22
Meta-analysis of Enhanced Recovery After Surgery (ERAS) Protocols in Emergency Abdominal Surgery. 61
31897698 2020
23
Thirty-Day Morbidity After Simultaneous Resection of Colorectal Cancer and Colorectal Liver Metastasis: American College of Surgeons NSQIP Analysis. 61
32007534 2020
24
Intracorporeal Versus Extracorporeal Anastomosis in Laparoscopic Right Colectomy: An Updated Systematic Review and Cumulative Meta-Analysis. 61
31971867 2020
25
Safety of hospital discharge before return of bowel function after elective colorectal surgery. 61
31976560 2020
26
Acute intestinal failure: International multicenter point-of-prevalence study. 61
30683610 2020
27
Imaging and treatment of idiopathic abdominal cocoon in 9 patients. 61
31885704 2020
28
Paralytic ileus precipitating platypnoea-orthodeoxia after right pneumonectomy. 61
31363746 2020
29
Effect of Caffeine Intake on Postoperative Ileus: A Systematic Review and Meta-Analysis. 61
30636241 2020
30
Re: Reduction in Postoperative Ileus Rates Utilizing Lower Pressure Pneumoperitoneum in Robotic-Assisted Radical Prostatectomy. 61
31909660 2020
31
Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery. 61
31595986 2020
32
Risk Factors for Prolonged Postoperative Ileus in Colorectal Surgery: A Systematic Review and Meta-analysis. 61
31912254 2020
33
Like a "Rolling" Gallstone: Cholecystoduodenal Fistula as Evidence of Gallstone Ileus. 61
31989397 2020
34
Potential Association Between Perioperative Fluid Management and Occurrence of Postoperative Ileus. 61
31633601 2020
35
Endoscopic Nasoenteral Feeding Tube Fixation with Hemoclip Reduces Tube Dislodgement. 61
31367879 2020
36
Novel approach to intraoperative peritoneal lavage with an extracorporeal stirring method in laparoscopic surgery for generalized peritonitis: Preliminary results. 61
30672137 2020
37
Outcomes After Bowel Resection for Inflammatory Bowel Disease in the Era of Surgical Care Bundles and Enhanced Recovery. 61
31468328 2020
38
BEVA primary care clinical guidelines: Analgesia. 61
31657050 2020
39
Isolated myeloid sarcoma presenting with small bowel obstruction: a case report. 61
31900687 2020
40
A Study of Three-Dimensional Versus Two-Dimensional Laparoscopic Surgery in Resection of Congenital Choledochal Cyst of Children and Jejunum Roux-en-Y Anastomosis. 61
31928494 2020
41
Enhanced postoperative recovery: good from afar, but far from good? 61
31903577 2020
42
Feasibility of laparoscopy gastrectomy for gastric cancer in the patients with high body mass index: A systematic review and meta-analysis. 61
31036475 2020
43
Indications for Nonoperative Management of Uncomplicated Appendicitis in Children: A Prospective Analysis at a Single Institution. 61
31859590 2020
44
Feasibility of perioperative volatile organic compound breath testing for prediction of paralytic ileus following laparoscopic colorectal resection. 61
31344300 2020
45
Chyme Reinfusion Is Associated with Lower Rate of Postoperative Ileus in Crohn's Disease Patients After Stoma Closure. 61
31367878 2020
46
Correction to: Incidence and Risk Factors for Severity of Postoperative Ileus After Colorectal Surgery: A Prospective Registry Data Analysis. 61
31993721 2020
47
A case report and review of the literature of Bouveret syndrome. 61
31859521 2020
48
[Impact of bowel preparation on surgical site infections and anastomotic leakage after elective colon resection: results of a retrospective study with 260 patients]. 61
31915873 2020
49
Implementation of liposomal bupivacaine transversus abdominis plane blocks into the colorectal enhanced recovery after surgery protocol: a natural experiment. 61
31797098 2020
50
Tension-Free Mesh Repair for Incarcerated Groin Hernia: A Comparative Study. 61
31994450 2020
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Variations for Ileus

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Expression for Ileus

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Search GEO for disease gene expression data for Ileus.
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Pathways for Ileus

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Pathways related to Ileus according to GeneCards Suite gene sharing:

(show all 20)
# Super pathways Score Top Affiliating Genes
1
Signaling by GPCR 65
Show member pathways
 13.94 VIP TNF SST OPRM1 MLN INS
2
Peptide ligand-binding receptors 65
Show member pathways
 13.14 VIP SST OPRM1 MLN GHSR GHRL
4
cAMP signaling pathway 36
12.1 VIP SST GHSR GHRL CFTR
5
Folate Metabolism 1
Show member pathways
 12.05 TNF INS IL6 F2 CRP
6
Interleukin-4 and 13 signaling 65
11.81 TNF OPRM1 IL6 IL10
7
Pertussis 36
11.65 TNF IL6 IL10
8
Dendritic Cells Developmental Lineage Pathway 64
11.63 TNF IL6 IL10
9
Microglia Activation During Neuroinflammation: Microglia Polarization 64
11.6 TNF IL6 IL10
10
Lung fibrosis 1
11.53 TNF IL6 CALCA
11
Malaria 36
11.41 TNF IL6 IL10
12
Interleukin-10 signaling 65
11.39 TNF IL6 IL10
13
Transcription_Role of VDR in regulation of genes involved in osteoporosis 22
11.34 TNF IL6 CALCA
14
African trypanosomiasis 36
11.24 TNF IL6 IL10
15
Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 1
11.23 TNF SST SLC9A3 IL6 IL10
16
IL-10 Pathway 63
11.2 TNF IL6 IL10
17
Cytokines and Inflammatory Response 1
11.07 TNF IL6 IL10
18
Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics 60
10.73 INS GHSR GHRL
19
Overview of nanoparticle effects 1
10.41 TNF IL6 CRP
20
Gastric acid production 1
10.39 VIP CCK
Sources

GO Terms for Ileus

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Cellular components related to Ileus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.7 TNF SST INS IL6 IL10 GHRL
2 perikaryon GO:0043204 9.46 VIP OPRM1 CRH CCK
3 extracellular region GO:0005576 9.44 VIP TNF SST MLN INS IL6

Biological processes related to Ileus according to GeneCards Suite gene sharing:

(show all 41)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.16 VIP OPRM1 INS IL6 IL10 GUCY2C
2 positive regulation of cell proliferation GO:0008284 10.08 VIP INS IL6 F2 CRH CCK
3 cellular protein metabolic process GO:0044267 9.98 INS IL6 F2 CALCA
4 positive regulation of gene expression GO:0010628 9.97 TNF SLC26A9 INS IL6 CRP CRH
5 cellular response to lipopolysaccharide GO:0071222 9.94 TNF IL6 IL10 GHSR
6 inflammatory response GO:0006954 9.91 TNF IL6 IL10 CRP CRH CALCA
7 response to glucocorticoid GO:0051384 9.84 TNF IL6 IL10
8 glucose metabolic process GO:0006006 9.83 TNF INS GHRL
9 learning or memory GO:0007611 9.83 VIP GHSR CRH
10 positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 9.77 GHRL CRH CFTR
11 digestion GO:0007586 9.73 SST GUCY2C CCK
12 positive regulation of cytokine secretion GO:0050715 9.72 TNF INS IL10
13 positive regulation of sprouting angiogenesis GO:1903672 9.71 IL10 GHSR GHRL
14 negative regulation of blood vessel diameter GO:0097756 9.68 INS CRP
15 negative regulation of appetite GO:0032099 9.68 GHSR CCK
16 adult feeding behavior GO:0008343 9.68 GHSR GHRL
17 postsynaptic modulation of chemical synaptic transmission GO:0099170 9.67 GHSR GHRL
18 negative regulation of interleukin-6 biosynthetic process GO:0045409 9.67 GHSR GHRL
19 endothelial cell apoptotic process GO:0072577 9.66 TNF IL10
20 negative regulation of norepinephrine secretion GO:0010700 9.66 GHSR CRH
21 positive regulation of behavioral fear response GO:2000987 9.65 CRH CCK
22 positive regulation of blood vessel diameter GO:0097755 9.65 VIP INS CALCA
23 growth hormone secretion GO:0030252 9.64 GHSR GHRL
24 negative regulation of cytokine secretion involved in immune response GO:0002740 9.63 TNF IL10
25 positive regulation of corticotropin secretion GO:0051461 9.63 GHRL CRH
26 hormone-mediated apoptotic signaling pathway GO:0008628 9.62 SST CRH
27 regulation of transmission of nerve impulse GO:0051969 9.62 GHSR GHRL
28 acute-phase response GO:0006953 9.62 INS IL6 F2 CRP
29 positive regulation of cortisol secretion GO:0051464 9.61 GHRL CRH
30 regulation of gastric motility GO:1905333 9.59 GHSR GHRL
31 positive regulation of small intestine smooth muscle contraction GO:1904349 9.58 GHSR GHRL
32 positive regulation of eating behavior GO:1904000 9.58 GHSR GHRL
33 negative regulation of tumor necrosis factor biosynthetic process GO:0042536 9.58 IL10 GHSR GHRL
34 receptor biosynthetic process GO:0032800 9.57 TNF IL10
35 regulation of sensory perception of pain GO:0051930 9.56 VIP OPRM1 IL10 CCK
36 negative regulation of lipid storage GO:0010888 9.54 TNF IL6 CRP
37 positive regulation of small intestinal transit GO:0120058 9.52 GHSR GHRL
38 negative regulation of circadian sleep/wake cycle, REM sleep GO:0042322 9.51 GHRL CRH
39 positive regulation of JAK-STAT cascade GO:0046427 9.46 TNF IL6 IL10 F2
40 G protein-coupled receptor signaling pathway GO:0007186 9.36 VIP SST OPRM1 MLN INS GHSR
41 positive regulation of appetite GO:0032100 9.13 OPRM1 GHSR GHRL

Molecular functions related to Ileus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.23 VIP SST MLN INS GHRL CRH
2 peptide hormone receptor binding GO:0051428 9.16 VIP CCK
3 neuropeptide hormone activity GO:0005184 9.13 VIP CRH CCK
Sources

Sources for Ileus

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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