MCID: IMM002
MIFTS: 25

Immature Cataract

Categories: Eye diseases, Genetic diseases, Neuronal diseases

Aliases & Classifications for Immature Cataract

MalaCards integrated aliases for Immature Cataract:

Name: Immature Cataract 12 15 71
Incipient Senile Cataract 12 71
Incipient Cataract 12 71
Water Clefts 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10997
SNOMED-CT 67 52421005
ICD10 32 H25.0 H25.09
UMLS 71 C0271163 C2939157 C2960113

Summaries for Immature Cataract

Disease Ontology : 12 A senile cataract that is characterized by variable opacification of the lens of the eye with some clear lens fibers remaining.

MalaCards based summary : Immature Cataract, also known as incipient senile cataract, is related to phacolytic glaucoma and cataract. An important gene associated with Immature Cataract is CRYAA (Crystallin Alpha A). The drugs Dipivefrin and tannic acid have been mentioned in the context of this disorder. Affiliated tissues include eye and endothelial.

Related Diseases for Immature Cataract

Graphical network of the top 20 diseases related to Immature Cataract:



Diseases related to Immature Cataract

Symptoms & Phenotypes for Immature Cataract

Drugs & Therapeutics for Immature Cataract

Drugs for Immature Cataract (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dipivefrin Approved 52365-63-6 3105
2
tannic acid Approved 1401-55-4
3
Benzocaine Approved, Investigational 94-09-7, 1994-09-7 2337

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Asymmetric Elongation of Foveal Tissue After Macular Hole Surgery and Its Impact on Metamorphopsia Completed NCT01471912
2 Outcomes of Resident-Performed Laser-Assisted vs Manual Traditional Phacoemulsification Completed NCT02561104

Search NIH Clinical Center for Immature Cataract

Genetic Tests for Immature Cataract

Anatomical Context for Immature Cataract

MalaCards organs/tissues related to Immature Cataract:

40
Eye, Endothelial

Publications for Immature Cataract

Articles related to Immature Cataract:

(show all 50)
# Title Authors PMID Year
1
Social impact indicators in patient diagnosed of senile cataract treated with phacoemulsification plus intraocular lens implantation. 61
32538985 2020
2
Ophthalmic examination findings and intraocular pressures in wild-caught African giant pouched rats (Cricetomys spp.). 61
29251400 2018
3
Comparative Study of Extra Capsular Cataract Extraction (ECCE) and Small Incision Cataract Surgery (SICS): Experience on Cataract Surgery in a Tertiary Center of Army Hospital, Kathmandu. 61
31056560 2018
4
Rapid macular hole formation and closure in a vitrectomized eye following rhegmatogenous retinal detachment repair. 61
29563703 2018
5
Microsporidial infection masquerading as graft rejection post-Descemet's stripping automated endothelial keratoplasty. 61
28905834 2017
6
Intracameral mydriatics versus topical mydriatics in pupil dilation for phacoemulsification cataract surgery. 61
28917402 2017
7
[The concentration of cerebral natriuretic peptide in tear and blood serum.] 61
30856302 2017
8
A case of keratitis associated with limbal relaxing incision. 61
28112139 2016
9
Phacoantigenic Reaction Masquerading as Postoperative Endophthalmitis in a Silicone Oil-filled Eye. 61
27994397 2016
10
Central corneal thickness changes in bevel-up versus bevel-down phacoemulsification cataract surgery: study protocol for a randomised, triple-blind, parallel group trial. 61
27687899 2016
11
[Intraocular pressure measurement inside the anterior chamber: a new technical solution and results]. 61
28121293 2016
12
Clinical study on evaluation of anti-cataract effect of Triphaladi Ghana Vati and Elaneer Kuzhambu Anjana in Timira (immature cataract). 61
27313415 2015
13
Manuel's asteroid disruption technique. 61
23571244 2015
14
Corneal edema after phacoemulsification surgery in patients with type II diabetes mellitus. 61
24172560 2013
15
Vacuum-assisted continuous circular capsulorhexis using bimanual irrigation and aspiration system of phaco machine in immature cataract. 61
24303209 2013
16
[Biometry of anterior segment structures: comparative study]. 61
21394995 2010
17
Phacoemulsification versus small incision cataract surgery (SICS): which one is a better surgical option for immature cataract in developing countries? 61
21141000 2009
18
[Phacoemulsification in eyes with white cataracts: results and complications]. 61
18046274 2007
19
Pattern of eye diseases and visual impairment among students in southwestern Nigeria. 61
17585376 2007
20
Management of bilateral uveitis in a Toxoplasma gondii-seropositive cat with histopathologic evidence of fungal panuveitis. 61
17565553 2007
21
The effect of a topical antioxidant formulation including N-acetyl carnosine on canine cataract: a preliminary study. 61
16939459 2006
22
[Optic coherent tomography in patients with immature cataract and pseudophakia]. 61
16927778 2006
23
Prevalence and causes of blindness and visual impairment among school children in south-western Nigeria. 61
17200795 2005
24
Incidence of and risk factors for residual posterior capsule opacification after cataract surgery. 61
15519088 2004
25
Excessive maternal caffeine exposure during pregnancy is cataractogenic for neonatal crystalline lenses in rats: a biomicroscopic and histopathologic study. 61
15453852 2004
26
Lens morphometry determined by B-mode ultrasonography of the normal and cataractous canine lens. 61
14982588 2004
27
Effect of nicotine exposure during gestation on neonatal rat crystalline lenses. 61
14707970 2004
28
Long-term management of a glaucomatous eye in a dog treated with medical therapy alone. 61
11789611 2001
29
Posterior lenticonus with congenital cataract in a Shih Tzu dog. 61
11129866 2000
30
Myopia among the Inuit population of East Greenland. Longitudinal Study 1950-1994. 61
9527340 1997
31
[Biochemical aspects in the pathogenesis of senile cataract]. 61
9409962 1997
32
Ultrasonographic abnormalities in the eyes of dogs with cataracts: 147 cases (1986-1992). 61
8226239 1993
33
Advanced versus immature cataracts--a preliminary report. 61
2764436 1989
34
New quantitative method to determine protein concentration and cell number in aqueous in vivo. 61
3054216 1988
35
Changes in the distribution of lens calcium during development of x-ray cataract. 61
6224754 1983
36
Ophthalmic technology for the clinician: direct ophthalmoscopy revisited. 61
7165227 1982
37
The Verhoeff capsule forceps: clinical and experimental results. 61
7247198 1981
38
Immune complexes in the aqueous humor and serum. 61
900214 1977
39
[Slit lamp studies on incipient senile cataract. II]. 61
5102428 1971
40
[Slit lamp studies on incipient senile cataract. I]. 61
5099710 1971
41
Use of 'Caracsol' (sodium-iodide in phospho-mono-calcic vehicle) in cases of incipient senile cataract. 61
6065036 1967
42
[Incipient senile cataract and presbyopia]. 61
5873273 1965
43
[Histopathological observations of human immature cataract]. 61
5894440 1965
44
[Remote results of the treatment of incipient senile cataract by instillation of drops containing cysteine]. 61
5887603 1965
45
Alterations in the Capsular Epithelium in Immature Cataract. 61
16693270 1941
46
Preliminary Capsulotomy in the Operation for the Extraction of Immature Cataract. 61
16692312 1914
47
The Treatment of Immature Cataract. 61
29006593 1908
48
The treatment of immature cataract. 61
16692145 1908
49
Extraction of lens in capsule as a method of procedure in cases of immature cataract. 61
16692079 1906
50
A Discussion on the Treatment of Immature Cataract. 61
20752810 1889

Variations for Immature Cataract

Expression for Immature Cataract

Search GEO for disease gene expression data for Immature Cataract.

Pathways for Immature Cataract

GO Terms for Immature Cataract

Cellular components related to Immature Cataract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integrator complex GO:0032039 8.62 INTS9 INTS12

Biological processes related to Immature Cataract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 snRNA transcription by RNA polymerase II GO:0042795 8.96 INTS9 INTS12
2 snRNA processing GO:0016180 8.62 INTS9 INTS12

Sources for Immature Cataract

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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