MCID: IMM005
MIFTS: 25

Immature Teratoma of Ovary

Categories: Cancer diseases, Endocrine diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Immature Teratoma of Ovary

MalaCards integrated aliases for Immature Teratoma of Ovary:

Name: Immature Teratoma of Ovary 12 59 15 72
Malignant Teratoma of Ovary 12 59
Ovarian Malignant Teratoma 59
Ovarian Immature Teratoma 59

Characteristics:

Orphanet epidemiological data:

59
malignant teratoma of ovary
Age of onset: Adolescent,Adult,Childhood,Infancy;

Classifications:



External Ids:

Disease Ontology 12 DOID:6331
NCIt 50 C8111
ICD10 via Orphanet 34 C56
Orphanet 59 ORPHA398987
UMLS 72 C0346182

Summaries for Immature Teratoma of Ovary

Disease Ontology : 12 A malignant ovarian germ cell neoplasm that is a teratoma containing variable amounts of immature (typically primitive/embryonal neuroectodermal) tissues, including, in its most primitive forms, embryoid bodies.

MalaCards based summary : Immature Teratoma of Ovary, also known as malignant teratoma of ovary, is related to childhood immature teratoma of ovary and germ cells tumors. An important gene associated with Immature Teratoma of Ovary is CEACAM5 (CEA Cell Adhesion Molecule 5). The drugs Ribavirin and Palivizumab have been mentioned in the context of this disorder. Affiliated tissues include ovary, bone and bone marrow.

Related Diseases for Immature Teratoma of Ovary

Diseases related to Immature Teratoma of Ovary via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 33)
# Related Disease Score Top Affiliating Genes
1 childhood immature teratoma of ovary 12.6
2 germ cells tumors 10.5
3 teratoma, ovarian 10.4
4 ovarian germ cell teratoma 10.4
5 teratoma 10.3
6 germ cell cancer 10.3
7 mature teratoma 10.2
8 ovarian germ cell cancer 10.2
9 cystic teratoma 10.2
10 glioblastoma multiforme 10.2
11 glioblastoma 10.2
12 gliomatosis peritonei 10.0
13 growing teratoma syndrome 10.0
14 gonadoblastoma 10.0
15 ewing sarcoma 10.0
16 sexual disorder 10.0
17 respiratory failure 10.0
18 gonadal dysgenesis 10.0
19 endodermal sinus tumor 10.0
20 endometriosis 10.0
21 dysgerminoma 10.0
22 infertility 10.0
23 testicular yolk sac tumor 10.0
24 peritonitis 10.0
25 encephalitis 10.0
26 chromosomal triplication 10.0
27 embryonal sarcoma 10.0
28 ewing's family of tumors 10.0
29 ovarian epithelial cancer 10.0
30 syndrome of inappropriate antidiuretic hormone 10.0
31 extraskeletal ewing sarcoma 10.0
32 embryonal carcinoma 10.0
33 malignant teratoma 10.0

Graphical network of the top 20 diseases related to Immature Teratoma of Ovary:



Diseases related to Immature Teratoma of Ovary

Symptoms & Phenotypes for Immature Teratoma of Ovary

Drugs & Therapeutics for Immature Teratoma of Ovary

Drugs for Immature Teratoma of Ovary (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 77)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ribavirin Approved Phase 3 36791-04-5 37542
2
Palivizumab Approved, Investigational Phase 3 188039-54-5
3
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
4
Captopril Approved Phase 3 62571-86-2 44093
5
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
6
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
7
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
8
Caspofungin Approved Phase 3 179463-17-3, 162808-62-0 468682 2826718
9
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
10
Cisplatin Approved Phase 3 15663-27-1 84093 441203 2767
11
Etoposide Approved Phase 3 33419-42-0 36462
12
Carboplatin Approved Phase 3 41575-94-4 10339178 498142 38904
13
Bleomycin Approved, Investigational Phase 3 11056-06-7 5360373
14 Alkylating Agents Phase 3
15 Antineoplastic Agents, Alkylating Phase 3
16 Antibodies Phase 3
17 Antibodies, Monoclonal Phase 3
18 Immunoglobulins Phase 3
19 Antiviral Agents Phase 3
20 Antimetabolites Phase 3
21 Anti-Infective Agents Phase 3
22 Hormone Antagonists Phase 3
23 Hormones Phase 3
24 Immunosuppressive Agents Phase 3
25 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
26 Antihypertensive Agents Phase 3
27 HIV Protease Inhibitors Phase 3
28 Immunologic Factors Phase 3
29 Angiotensin-Converting Enzyme Inhibitors Phase 3
30
protease inhibitors Phase 3
31 Antirheumatic Agents Phase 3
32 14-alpha Demethylase Inhibitors Phase 3
33 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
34 Cytochrome P-450 CYP3A Inhibitors Phase 3
35 Antifungal Agents Phase 3
36 Cytochrome P-450 Enzyme Inhibitors Phase 3
37 Steroid Synthesis Inhibitors Phase 3
38
Hydroxyitraconazole Phase 3
39 Cytochrome P-450 CYP2C19 Inhibitors Phase 3
40 Liposomal amphotericin B Phase 3
41 Antiparasitic Agents Phase 3
42 Antiprotozoal Agents Phase 3
43 Antineoplastic Agents, Phytogenic Phase 3
44 Tubulin Modulators Phase 3
45 Antimitotic Agents Phase 3
46 Topoisomerase Inhibitors Phase 3
47 Etoposide phosphate Phase 3
48 Antibiotics, Antitubercular Phase 3
49 Anti-Bacterial Agents Phase 3
50 Keratolytic Agents Phase 3

Interventional clinical trials:

(show all 17)
# Name Status NCT ID Phase Drugs
1 A Randomized Double-Blind Placebo-Controlled Phase III Study To Evaluate The Safety And Efficacy Of Palivizumab Combined With Aerosolized Ribavirin Compared To Ribavirin Alone To Treat RSV Pneumonia In Patients With Bone Marrow Transplants (BMT) Completed NCT00014391 Phase 3 ribavirin
2 Phase III Study of Captopril in Patients Undergoing Autologous Bone Marrow/Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
3 A Randomized, Comparative Study of Itraconazole Versus Fluconazole for Prevention of Aspergillus Infections in Peripheral Blood Stem Cell and Marrow Transplant Recipients Completed NCT00003883 Phase 3 fluconazole;itraconazole
4 A Multicenter, Double-Blind, Randomized, Comparative Study To Evaluate The Safety, Tolerability, And Efficacy Of MK-0991 Versus (Amphotericin B) Liposome For Injection As Empirical Therapy In Patients With Persistent Fever And Neutropenia Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
5 A Strategic Study to Determine the Optimal Moment to Initiate Systemic Antifungal Therapy With Ambisome in Granulocytopenic Cancer Patients With Unexplained Fever Refractory to Empirical Antibacterials Completed NCT00003938 Phase 3 liposomal amphotericin B
6 A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients With Germ Cell Tumors Recruiting NCT03067181 Phase 3 Bleomycin;Carboplatin;Cisplatin;Etoposide;Etoposide Phosphate
7 A Phase II Study of Sunitinib in Patients With Refractory or Relapsed Germ Cell Tumors Completed NCT00453310 Phase 2 sunitinib malate
8 Phase II Trial of Paclitaxel, Ifosfamide, and Cisplatin in Previously Untreated Intermediate and Poor Risk Germ Cell Tumor Patients Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
9 Tandem High-Dose Chemotherapy With Autologous Stem Cell Rescue for Poor-Prognosis Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
10 Oral Beclomethasone Dipropionate Capsules for Treatment of Intestinal Graft-Versus-Host Disease: Compassionate Use in Patients With Contraindictions to High-Dose Immunosuppressive Therapy Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
11 Combination of Interleukin 11 (Neumega) With G-CSF to Mobilize Autologous Peripheral Blood Stem Cells (PBSC) Completed NCT00004157 Phase 2
12 Donor Lymphocyte Infusion (DLI) as Adoptive Immunotherapy for Relapse Malignancies After Allogeneic Hematopoietic Transplantation Completed NCT00003887 Phase 2
13 Cytokine-Based Immunotherapy Following High-Dose Chemotherapy and Autologous Stem Cell Transplantation Completed NCT00003408 Phase 2
14 A PHASE II STUDY OF CELLULAR ADOPTIVE IMMUNOTHERAPY AS PROPHYLAXIS FOR CYTOMEGALOVIRUS DISEASE AFTER ALLOGENEIC BONE MARROW TRANSPLANTATION Completed NCT00002673 Phase 2
15 A Phase I Trial of Recombinant Human Interleukin-12 After High-Dose Therapy and Autologous Hematopoietic Stem Cell Support Completed NCT00003107 Phase 1
16 A Randomized, Placebo-Controlled, Blinded Study Of Acupuncture Therapy In Mucositis-Related Pain In Patients Undergoing Hematopoietic Stem Cell Transplantation Completed NCT00060021
17 Multi-Site Randomized Clinical Trial Comparing Standard Recovery Preparation to Extended Recovery Preparation to Enhance Long Term Function After Marrow or Stem Cell Transplant Completed NCT00049465

Search NIH Clinical Center for Immature Teratoma of Ovary

Genetic Tests for Immature Teratoma of Ovary

Anatomical Context for Immature Teratoma of Ovary

MalaCards organs/tissues related to Immature Teratoma of Ovary:

41
Ovary, Bone, Bone Marrow

Publications for Immature Teratoma of Ovary

Articles related to Immature Teratoma of Ovary:

# Title Authors PMID Year
1
Growing Teratoma Syndrome Following Treatment for Immature Teratoma of Ovary-A Case Report and Review of Literature. 38
28706371 2017
2
Gliomatosis Peritonei Arising in Setting of Immature Teratoma of Ovary: A Case Report and Review of Literature. 38
27298531 2016
3
Immature teratoma of ovary--outcome following primary and secondary surgery: study of a single institution cohort. 38
26142911 2015
4
Ovarian immature teratoma during pregnancy: a case report. 38
25807726 2014
5
Immature teratoma of ovary composed largely of choroid plexus. 38
20683425 2010
6
Identification of two different surface epitopes of human ovarian epithelial carcinomas by monoclonal antibodies. 38
2580620 1985
7
SOLID MALIGNANT TERATOMA OF OVARY WITH EMBRYONAL CARCINOMA. 38
14134285 1963

Variations for Immature Teratoma of Ovary

Expression for Immature Teratoma of Ovary

Search GEO for disease gene expression data for Immature Teratoma of Ovary.

Pathways for Immature Teratoma of Ovary

GO Terms for Immature Teratoma of Ovary

Sources for Immature Teratoma of Ovary

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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