MCID: IMM039
MIFTS: 28

Immune Hydrops Fetalis

Categories: Fetal diseases, Rare diseases, Immune diseases

Aliases & Classifications for Immune Hydrops Fetalis

MalaCards integrated aliases for Immune Hydrops Fetalis:

Name: Immune Hydrops Fetalis 59 73
Immune Fetal Hydrops 59
Immune Fetal Edema 59
Immune Hf 59
Ihf 59

Characteristics:

Orphanet epidemiological data:

59
immune hydrops fetalis
Inheritance: Not applicable; Prevalence: 1-5/10000 (United Kingdom); Age of onset: Antenatal,Neonatal; Age of death: embryofetal,infantile,stillbirth;

Classifications:



External Ids:

Orphanet 59 ORPHA364013
UMLS via Orphanet 74 C0455990
ICD10 via Orphanet 34 P56.0
UMLS 73 C0455990

Summaries for Immune Hydrops Fetalis

MalaCards based summary : Immune Hydrops Fetalis, also known as immune fetal hydrops, is related to hydrops fetalis and lysosomal storage disease. An important gene associated with Immune Hydrops Fetalis is GUSB (Glucuronidase Beta), and among its related pathways/superpathways are Porphyrin and chlorophyll metabolism and Lysosome. Affiliated tissues include pituitary, lung and bone, and related phenotype is mortality/aging.

Related Diseases for Immune Hydrops Fetalis

Graphical network of the top 20 diseases related to Immune Hydrops Fetalis:



Diseases related to Immune Hydrops Fetalis

Symptoms & Phenotypes for Immune Hydrops Fetalis

MGI Mouse Phenotypes related to Immune Hydrops Fetalis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.02 GBA GUSB HBA2 PIEZO1 UROS

Drugs & Therapeutics for Immune Hydrops Fetalis

Search Clinical Trials , NIH Clinical Center for Immune Hydrops Fetalis

Genetic Tests for Immune Hydrops Fetalis

Anatomical Context for Immune Hydrops Fetalis

MalaCards organs/tissues related to Immune Hydrops Fetalis:

41
Pituitary, Lung, Bone

Publications for Immune Hydrops Fetalis

Articles related to Immune Hydrops Fetalis:

(show top 50) (show all 85)
# Title Authors Year
1
Thymic teratoma presenting as non-immune hydrops fetalis. ( 29515979 )
2018
2
Inborn errors of metabolism in a cohort of pregnancies with non-immune hydrops fetalis: a single center experience. ( 28822227 )
2017
3
Non-Immune Hydrops Fetalis: Do Placentomegaly and Polyhydramnios Matter? ( 29076544 )
2017
4
Perinatal and one-year outcomes of non-immune hydrops fetalis by etiology and age at diagnosis. ( 26712114 )
2016
5
A Rare Association of Non-Compaction of the Ventricular Myocardium, and Non-Immune Hydrops Fetalis. ( 27328555 )
2016
6
Congenital Disorder of Glycosylation (CDG) Presenting as Non-immune Hydrops Fetalis. ( 26365158 )
2015
7
Maternal and fetal capillary malformation-arteriovenous malformation (CM-AVM) due to a novel RASA1 mutation presenting with prenatal non-immune hydrops fetalis. ( 26096958 )
2015
8
Etiology of non-immune hydrops fetalis: An update. ( 25712632 )
2015
9
Non-immune Hydrops fetalis due to Parvovirus B19 Infection in 2 Extremely Preterm Infants: Perinatal Management and Long-term Neurodevelopmental Outcome. ( 25830498 )
2015
10
Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis. ( 26333996 )
2015
11
Non-immune hydrops fetalis without anemia due to parvovirus B19. ( 24140219 )
2014
12
Non-immune hydrops fetalis as a diagnostic and survival problems: what do we tell the parents? ( 25294712 )
2014
13
Accessory diaphragm associated with non-immune hydrops fetalis. ( 25100808 )
2014
14
Transient myeloproliferative disorder and non-immune hydrops fetalis in a neonate with trisomy 21. ( 24473698 )
2014
15
Non-immune hydrops fetalis. ( 24283082 )
2013
16
Cholestasis in infants with immune hydrops fetalis. ( 24577980 )
2013
17
Non-immune hydrops fetalis: A prospective study of 53 cases. ( 24039125 )
2013
18
Non-immune hydrops fetalis caused by herpes simplex virus type 2 in the setting of recurrent maternal infection. ( 24071962 )
2013
19
Intrauterine blood transfusion in immune hydrops fetalis, corrects middle cerebral artery Doppler velocimetry very quickly. ( 22364302 )
2012
20
CCBE1 mutations can cause a mild, atypical form of generalized lymphatic dysplasia but are not a common cause of non-immune hydrops fetalis. ( 22239599 )
2012
21
Are alanine, cysteine, glycine and valine amino acids the cause of non-immune hydrops fetalis? ( 23157039 )
2012
22
Non-immune hydrops fetalis: a short review of etiology and pathophysiology. ( 22302731 )
2012
23
Short-term and long-term outcomes of 214 cases of non-immune hydrops fetalis. ( 21592689 )
2011
24
Amniotic fluid amino acid levels in non-immune hydrops fetalis: a case-control study. ( 21833460 )
2011
25
Prenatal diagnosis of non-immune hydrops fetalis: what do we tell the parents? ( 21268039 )
2011
26
Immunohistochemistry in non-immune hydrops fetalis: a single center experience in 79 fetuses. ( 20425823 )
2010
27
Acute non-immune hydrops fetalis caused by intrauterine echovirus infection. ( 22791477 )
2010
28
Successful outcome with intrauterine transfusion in non-immune hydrops fetalis secondary to congenital syphilis. ( 21050519 )
2010
29
Zellweger syndrome with unusual findings: non-immune hydrops fetalis, dermal erythropoiesis and hypoplastic toe nails. ( 20033294 )
2009
30
A diagnostic flow chart for non-immune hydrops fetalis. ( 19334092 )
2009
31
Recurrent non-immune hydrops fetalis with gracile bones and dysmorphic features in siblings. ( 18478587 )
2008
32
Fetal cerebellar hemorrhage in parvovirus-associated non-immune hydrops fetalis. ( 17763280 )
2007
33
Right-sided diaphragmatic eventration: a rare cause of non-immune hydrops fetalis. ( 17596732 )
2007
34
Lysosomal storage diseases in non-immune hydrops fetalis pregnancies. ( 16674934 )
2006
35
Severity of non-immune hydrops fetalis at birth continues to predict survival despite advances in perinatal care. ( 16757915 )
2006
36
Non-immune hydrops fetalis: prenatal diagnosis and perinatal outcomes. ( 15895940 )
2005
37
Etiology and outcome of non-immune hydrops fetalis in southern Thailand. ( 15637431 )
2005
38
Autosomal recessive non-immune hydrops fetalis caused by systemic lymphangiectasia. ( 15690379 )
2005
39
Pearson's syndrome: a rare cause of non-immune hydrops fetalis. ( 14986619 )
2003
40
A new case of mucopolysaccharidosis VII presenting as non immune hydrops fetalis. ( 12748853 )
2003
41
Mucopolysaccharidosis type VII as a cause of recurrent non-immune hydrops fetalis. ( 14711113 )
2003
42
A transgenic mouse model for non-immune hydrops fetalis induced by the NS1 gene of human parvovirus B19. ( 11807219 )
2002
43
A rare case of non-immune hydrops fetalis: double-chambered right ventricle. A case report. ( 11399891 )
2001
44
In utero erythrocyte transfusion for fetal xerocytosis associated with severe anemia and non-immune hydrops fetalis. ( 11483935 )
2001
45
Prenatal diagnosis of intrauterine cytomegalovirus infection in a fetus with non-immune hydrops fetalis. ( 11531622 )
2001
46
Non-immune hydrops fetalis in the first trimester: a review of 30 cases. ( 11530871 )
2001
47
Familial congenital pulmonary lymphangectasia, non-immune hydrops fetalis, facial and lower limb lymphedema: confirmation of Njolstad's report. ( 10946350 )
2000
48
A case of non-immune hydrops fetalis with congenital cystic adenomatoid malformation of the left lung in a twin. ( 11085057 )
2000
49
Direct intrauterine fetal therapy in a case of bronchopulmonary sequestration associated with non-immune hydrops fetalis. ( 10341405 )
1999
50
Long-term outcome of 51 liveborn neonates with non-immune hydrops fetalis. ( 10090542 )
1999

Variations for Immune Hydrops Fetalis

Expression for Immune Hydrops Fetalis

Search GEO for disease gene expression data for Immune Hydrops Fetalis.

Pathways for Immune Hydrops Fetalis

GO Terms for Immune Hydrops Fetalis

Cellular components related to Immune Hydrops Fetalis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lysosomal lumen GO:0043202 8.62 GBA GUSB

Molecular functions related to Immune Hydrops Fetalis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity, acting on glycosyl bonds GO:0016798 8.62 GBA GUSB

Sources for Immune Hydrops Fetalis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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