MCID: IMM053
MIFTS: 23

Immunotactoid Glomerulopathy

Categories: Rare diseases, Nephrological diseases, Immune diseases

Aliases & Classifications for Immunotactoid Glomerulopathy

MalaCards integrated aliases for Immunotactoid Glomerulopathy:

Name: Immunotactoid Glomerulopathy 53 59
Immunotactoid Glomerulonephritis 53 59
Fibrillary Glomerulonephritis 73

Characteristics:

Orphanet epidemiological data:

59
immunotactoid glomerulopathy
Inheritance: Not applicable; Age of onset: Adult;

Classifications:

Orphanet: 59  
Rare renal diseases


External Ids:

Orphanet 59 ORPHA97567
UMLS via Orphanet 74 C0268749 C2242534
ICD10 via Orphanet 34 N03.6
UMLS 73 C0268749

Summaries for Immunotactoid Glomerulopathy

NIH Rare Diseases : 53 Immunotactoid glomerulopathy, also known as glomerulonephritis with organized monoclonal microtubular immunoglobulin deposits (GOMMID),  is a very uncommon cause of glomerular disease. It is related to a similar disease known as fibrillary glomerulopathy, which is more common. Both disorders probably result from deposits derived from immunoglobulins, but in most cases the cause is idiopathic (unknown). On electron microscopy, immunotactoid glomerulopathy is characterized by the formation of microtubules which are much larger than the fibrils observed in fibrillary glomerulonephritis (30 to 50 versus 16 to 24 nm in diameter). The signs and symptoms include blood (hematuria) and protein (proteinuria) in the urine, kidney insufficiency and high blood pressure. Both fibrillary glomerulonephritis and immunotactoid glomerulopathy have been associated with hepatitis C virus infection and with malignancy and autoimmune disease. Also, patients with immunotactoid glomerulopathy have a greater risk to have chronic lymphocytic leukemia and B cell lymphomas and should be screened for all of these conditions. Treatment is generally determined by the severity of the kidney problems.

MalaCards based summary : Immunotactoid Glomerulopathy, also known as immunotactoid glomerulonephritis, is related to immunotactoid or fibrillary glomerulopathy and fibrillary glomerulonephritis. An important gene associated with Immunotactoid Glomerulopathy is ALB (Albumin). Affiliated tissues include kidney, b cells and bone.

Related Diseases for Immunotactoid Glomerulopathy

Diseases related to Immunotactoid Glomerulopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 27)
# Related Disease Score Top Affiliating Genes
1 immunotactoid or fibrillary glomerulopathy 12.3
2 fibrillary glomerulonephritis 11.8
3 glomerulopathy with fibronectin deposits 2 11.2
4 glomerulonephritis 10.4
5 hepatitis 10.1
6 lymphoma 10.1
7 hepatitis c 10.1
8 vasculitis 10.1
9 leukemia, chronic lymphocytic 2 10.0
10 leukemia, chronic lymphocytic 10.0
11 down syndrome 10.0
12 lymphoma, hodgkin, classic 10.0
13 mycosis fungoides 10.0
14 sickle cell anemia 10.0
15 lymphoma, non-hodgkin, familial 10.0
16 hypereosinophilic syndrome, idiopathic 10.0
17 b-cell lymphomas 10.0
18 diffuse large b-cell lymphoma 10.0
19 liver disease 10.0
20 heavy chain disease 10.0
21 nephrotic syndrome 10.0
22 poems syndrome 10.0
23 kidney disease 10.0
24 amyloidosis 10.0
25 hypereosinophilic syndrome 10.0
26 leukemia, b-cell, chronic 10.0
27 cytomegalovirus infection 10.0

Graphical network of the top 20 diseases related to Immunotactoid Glomerulopathy:



Diseases related to Immunotactoid Glomerulopathy

Symptoms & Phenotypes for Immunotactoid Glomerulopathy

Drugs & Therapeutics for Immunotactoid Glomerulopathy

Search Clinical Trials , NIH Clinical Center for Immunotactoid Glomerulopathy

Genetic Tests for Immunotactoid Glomerulopathy

Anatomical Context for Immunotactoid Glomerulopathy

MalaCards organs/tissues related to Immunotactoid Glomerulopathy:

41
Kidney, B Cells, Bone, Skin, Liver, Bone Marrow

Publications for Immunotactoid Glomerulopathy

Articles related to Immunotactoid Glomerulopathy:

(show top 50) (show all 58)
# Title Authors Year
1
A case of immunotactoid glomerulopathy with false-negative IgG staining. ( 29907095 )
2018
2
A case report of POEMS syndrome with renal involvement as immunotactoid glomerulopathy. ( 29489695 )
2018
3
Immunotactoid glomerulopathy leading to the discovery of POEMS syndromea8c. ( 28291506 )
2017
4
Immunotactoid glomerulopathy in a patient with hepatitis C viral infection. ( 28230481 )
2017
5
Immunotactoid Glomerulopathy of 10-Years' Duration: Insights Gained From Sequential Biopsies. ( 29270507 )
2017
6
A case report of unusually long lag time between immunotactoid glomerulopathy (itg) diagnosis and diffuse large B-cell lymphoma (DLBCL) development. ( 27686684 )
2016
7
Immunotactoid glomerulopathy with IGM positivity and associated IGM paraprotein. ( 27772927 )
2016
8
Immunotactoid Glomerulopathy and Cryoglobulinemic Nephropathy: Two Entities with Many Similarities. A Unified Conceptual Approach. ( 26270724 )
2015
9
AJKD Atlas of Renal Pathology: Immunotactoid Glomerulopathy. ( 26408243 )
2015
10
End-Stage Kidney Disease Due to Fibrillary Glomerulonephritis and Immunotactoid Glomerulopathy - Outcomes in 66 Consecutive ANZDATA Registry Cases. ( 26418732 )
2015
11
Laser microdissection and proteomic analysis of amyloidosis, cryoglobulinemic GN, fibrillary GN, and immunotactoid glomerulopathy. ( 23411427 )
2013
12
Immunotactoid glomerulopathy: clinicopathologic and proteomic study. ( 22872726 )
2012
13
Chronic lymphocytic leukemia associated with immunotactoid glomerulopathy: a case report of successful treatment with high-dose methylprednisolone in combination with rituximab followed by alemtuzumab. ( 22335532 )
2012
14
Spontaneous remission of immunotactoid glomerulopathy. ( 21934180 )
2011
15
Immunotactoid glomerulopathy and tuberculosis: a novel association. ( 21629347 )
2011
16
A case of immunotactoid glomerulopathy with rapid progression to end-stage renal disease. ( 20024509 )
2009
17
A case of recurrent immunotactoid glomerulopathy in an allograft treated with rituximab. ( 19917422 )
2009
18
A case of immunotactoid glomerulopathy exhibiting nephrotic syndrome successfully treated with corticosteroids and antihypertensive therapy. ( 19367362 )
2009
19
Plasma cell dyscrasia; LCDD vs Immunotactoid glomerulopathy. ( 18711301 )
2008
20
Fibrillary glomerulonephritis and immunotactoid glomerulopathy. ( 18045849 )
2008
21
Long-term remission of paraprotein-induced immunotactoid glomerulopathy after high-dose therapy and autologous blood stem cell transplantation. ( 17605010 )
2007
22
Immunotactoid glomerulopathy with microtubular deposits, with reference to the characteristics of Japanese cases. ( 15909596 )
2005
23
A 59-year-old woman with immunotactoid glomerulopathy, heavy-chain disease, and non-hodgkin lymphoma. ( 15163227 )
2004
24
Fibrillary glomerulonephritis and immunotactoid glomerulopathy. ( 15299095 )
2004
25
Immunotactoid glomerulopathy in an HIV-positive African-American man. ( 14655225 )
2003
26
Images in cardiovascular medicine. Fibrillary/immunotactoid glomerulopathy with cardiac involvement. ( 11956134 )
2002
27
Immunotactoid glomerulopathy. ( 11961029 )
2002
28
Immunotactoid glomerulopathy in sickle cell anemia. ( 11198611 )
2001
29
Immunotactoid glomerulopathy characterized by steroid-responsive massive subendothelial deposition. ( 11228198 )
2001
30
Immunotactoid glomerulopathy with massive bone marrow deposits in a patient with IgM kappa monoclonal gammopathy and hypocomplementemia. ( 11479168 )
2001
31
One case of immunotactoid glomerulopathy: morphological-ultrastructural aspects. ( 11846092 )
2001
32
Successful treatment of recurrence of immunotactoid glomerulopathy in a kidney allograft recipient. ( 10831649 )
2000
33
Fibrillary-immunotactoid glomerulopathy with renal deposits of IgAlambda: a rare cause of glomerulonephritis. ( 10604647 )
1999
34
Immunotactoid glomerulopathy--an unusual deposition disease: report of the first Malaysian case. ( 10879280 )
1999
35
A case of immunotactoid glomerulopathy with unusual microtubular deposits. ( 9617498 )
1998
36
Successful treatment with steroid pulse therapy in a case of immunotactoid glomerulopathy with hypocomplementemia. ( 10074587 )
1998
37
Immunotactoid glomerulopathy associated with idiopathic hypereosinophilic syndrome. ( 9653841 )
1998
38
Hepatitis C viral infection is associated with fibrillary glomerulonephritis and immunotactoid glomerulopathy. ( 9848778 )
1998
39
Immunotactoid glomerulopathy: report of a case. ( 9214417 )
1997
40
Immunotactoid glomerulopathy with extrarenal deposits in the bone, and chronic cholestatic liver disease. ( 8856222 )
1996
41
Clinical features, predictors of disease progression and results of renal transplantation in fibrillary/immunotactoid glomerulopathy. ( 8671905 )
1996
42
Immunotactoid glomerulopathy with unusually thick extracellular microtubules and nodular glomerulosclerosis in a diabetic patient. ( 7479381 )
1995
43
De novo immunotactoid glomerulopathy of the renal allograft: possible association with cytomegalovirus infection. ( 8023832 )
1994
44
Immunotactoid glomerulopathy: the case for Occam's razor. ( 8372842 )
1993
45
Immunotactoid glomerulopathy in a child with Down syndrome. ( 8439490 )
1993
46
Morphologic and clinical features of fibrillary glomerulonephritis versus immunotactoid glomerulopathy. ( 8372831 )
1993
47
Fibrillary glomerulonephritis and immunotactoid glomerulopathy: two entities, not one. ( 8372843 )
1993
48
Immunotactoid glomerulopathy (ITGP): a not fully defined clinicopathologic entity. ( 8516498 )
1993
49
Immunotactoid glomerulopathy. ( 1496977 )
1992
50
Nonamyloidotic fibrillary glomerulopathy, immunotactoid glomerulopathy, and the differential diagnosis of filamentous glomerulopathies. ( 2020659 )
1991

Variations for Immunotactoid Glomerulopathy

Expression for Immunotactoid Glomerulopathy

Search GEO for disease gene expression data for Immunotactoid Glomerulopathy.

Pathways for Immunotactoid Glomerulopathy

GO Terms for Immunotactoid Glomerulopathy

Sources for Immunotactoid Glomerulopathy

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