MCID: IMM051
MIFTS: 15

Immunotactoid or Fibrillary Glomerulopathy

Categories: Immune diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Immunotactoid or Fibrillary Glomerulopathy

MalaCards integrated aliases for Immunotactoid or Fibrillary Glomerulopathy:

Name: Immunotactoid or Fibrillary Glomerulopathy 52 58
Immunotactoid or Fibrillary Glomerulonephritis 52 58
Fibrillary Glomerulonephritis and Immunotactoid Glomerulopathy 52

Characteristics:

Orphanet epidemiological data:

58
immunotactoid or fibrillary glomerulopathy
Inheritance: Not applicable; Age of onset: Adult; Age of death: adult;

Classifications:

Orphanet: 58  
Rare renal diseases


External Ids:

ICD10 via Orphanet 33 N03.6
Orphanet 58 ORPHA91137

Summaries for Immunotactoid or Fibrillary Glomerulopathy

NIH Rare Diseases : 52 Immunotactoid or fibrillary glomerulopathy is a term that includes two conditions: immunotactoid glomerulopathy and fibrillary glomerulonephritis , which are uncommon causes of glomerular disease . Most experts feel that fibrillary glomerulonephritis and immunotactoid glomerulopathy are separate disorders but they have many similarities and some experts group these disorders together. Fibrillary glomerulonephritis and immunotactoid glomerulopathy can be distinguished from each other by electron microscopy ; the 'fibrils' that characterize fibrillary glomerulonephritis are smaller and randomly oriented as opposed to the larger and organized fibrils of immunotactoid glomerulopathy which also have microtubule formations . Both disorders probably result from deposits derived from immunoglobulins but in most cases the cause is idiopathic (unknown). The signs and symptoms are similar in both diseases and may include blood (hematuria) and protein (proteinuria ) in the urine, kidney insufficiency and high blood pressure . Fibrillary glomeurlonephritis is much more common than immunotactoid glomerulopathy. Both fibrillary glomerulonephritis and immunotactoid glomerulopathy have been associated with hepatitis C virus infection and with malignancy and autoimmune disease , but immunotactoid glomerulopathy patients have a greater predisposition to chronic lymphocytic leukemia and B cell lymphomas . All patients should be screened for these conditions. It is also important to rule out another disease known as amyloidosis . When the fibrils are stained with an acid dye known as "Congo red" the results are negative. In amyloidosis the results are positive because the dye is absorbed by the amyloids. Treatment is generally determined by the severity of the kidney problems.

MalaCards based summary : Immunotactoid or Fibrillary Glomerulopathy, also known as immunotactoid or fibrillary glomerulonephritis, is related to fibrillary glomerulonephritis and immunotactoid glomerulopathy. Affiliated tissues include kidney and b cells.

Related Diseases for Immunotactoid or Fibrillary Glomerulopathy

Diseases related to Immunotactoid or Fibrillary Glomerulopathy via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 fibrillary glomerulonephritis 12.2
2 immunotactoid glomerulopathy 12.1
3 glomerulonephritis 10.7
4 lymphoma, hodgkin, classic 10.3
5 lymphoma, non-hodgkin, familial 10.3
6 hepatitis c 10.3
7 cryoglobulinemia 10.3
8 membranoproliferative glomerulonephritis 10.3
9 kidney disease 10.3
10 glomerular disease 10.3

Graphical network of the top 20 diseases related to Immunotactoid or Fibrillary Glomerulopathy:



Diseases related to Immunotactoid or Fibrillary Glomerulopathy

Symptoms & Phenotypes for Immunotactoid or Fibrillary Glomerulopathy

Drugs & Therapeutics for Immunotactoid or Fibrillary Glomerulopathy

Search Clinical Trials , NIH Clinical Center for Immunotactoid or Fibrillary Glomerulopathy

Genetic Tests for Immunotactoid or Fibrillary Glomerulopathy

Anatomical Context for Immunotactoid or Fibrillary Glomerulopathy

MalaCards organs/tissues related to Immunotactoid or Fibrillary Glomerulopathy:

40
Kidney, B Cells

Publications for Immunotactoid or Fibrillary Glomerulopathy

Articles related to Immunotactoid or Fibrillary Glomerulopathy:

(show all 12)
# Title Authors PMID Year
1
End-Stage Kidney Disease Due to Fibrillary Glomerulonephritis and Immunotactoid Glomerulopathy - Outcomes in 66 Consecutive ANZDATA Registry Cases. 61
26418732 2015
2
[Fibrillary glomerulonephritis and immunotactoid glomerulopathy: case reports]. 61
22165079 2011
3
Contribution of electron microscopy to the final diagnosis of renal biopsies in Egyptian patients. 61
20645138 2011
4
Fibrillary glomerulonephritis and immunotactoid glomerulopathy. 61
18045849 2008
5
Pathology of glomerular deposition diseases and fibrillary glomerulopathies associated with paraproteinemia and haematopoietic disorder. 61
17995523 2007
6
Pathology of glomerular deposition diseases. 61
17685926 2007
7
Fibrillary glomerulonephritis and immunotactoid glomerulopathy. 61
15299095 2004
8
Hepatitis C viral infection is associated with fibrillary glomerulonephritis and immunotactoid glomerulopathy. 61
9848778 1998
9
Monoclonal immunoglobulin G1-kappa fibrillary glomerulonephritis. 61
9556416 1998
10
Glomerulonephritis with associated hypocomplementemia and crescents: an unusual case of fibrillary glomerulonephritis. 61
7579081 1995
11
Glomerulopathies of dysproteinemias, abnormal immunoglobulin deposition, and lymphoproliferative disorders. 61
7922263 1994
12
Fibrillary glomerulonephritis and immunotactoid glomerulopathy: two entities, not one. 61
8372843 1993

Variations for Immunotactoid or Fibrillary Glomerulopathy

Expression for Immunotactoid or Fibrillary Glomerulopathy

Search GEO for disease gene expression data for Immunotactoid or Fibrillary Glomerulopathy.

Pathways for Immunotactoid or Fibrillary Glomerulopathy

GO Terms for Immunotactoid or Fibrillary Glomerulopathy

Sources for Immunotactoid or Fibrillary Glomerulopathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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