MCID: IMP001
MIFTS: 30

Impetigo Herpetiformis

Categories: Skin diseases

Aliases & Classifications for Impetigo Herpetiformis

MalaCards integrated aliases for Impetigo Herpetiformis:

Name: Impetigo Herpetiformis 12 15 17 72

Classifications:



External Ids:

Disease Ontology 12 DOID:8503
ICD9CM 35 694.3
SNOMED-CT 68 65539006
ICD10 33 L40.1
UMLS 72 C1314968

Summaries for Impetigo Herpetiformis

Disease Ontology : 12 An impetigo that is characterized as a form of severe pustular psoriasis occurring in pregnancy.

MalaCards based summary : Impetigo Herpetiformis is related to impetigo and pustular psoriasis. An important gene associated with Impetigo Herpetiformis is IL36RN (Interleukin 36 Receptor Antagonist), and among its related pathways/superpathways are Defensins and IL-1 Family Signaling Pathways. Affiliated tissues include skin, monocytes and thyroid, and related phenotypes are hematopoietic system and immune system

Wikipedia : 75 Impetigo herpetiformis is a form of severe pustular psoriasis occurring in pregnancy which may occur... more...

Related Diseases for Impetigo Herpetiformis

Diseases related to Impetigo Herpetiformis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 87)
# Related Disease Score Top Affiliating Genes
1 impetigo 32.4 PI3 IL36RN ELANE
2 pustular psoriasis 32.1 TNF PI3 IL36RN ELANE CARD14
3 pustulosis of palm and sole 31.9 TNF IL36RN
4 psoriasis 31.4 TNF IL36RN CARD14
5 acrodermatitis 30.9 IL36RN ALB
6 skin disease 29.7 TNF PI3 IL36RN DST CARD14
7 psoriasis 14, pustular 10.6
8 hypoparathyroidism 10.6
9 bronchopneumonia 10.6 PI3 ELANE
10 pityriasis rubra pilaris 10.5 IL36RN CARD14
11 rapidly progressive glomerulonephritis 10.5 PRTN3 ELANE
12 placental insufficiency 10.5
13 dermatitis 10.4
14 irritant dermatitis 10.4 TNF PI3
15 dermatitis herpetiformis, familial 10.4
16 dermatitis herpetiformis 10.4
17 pemphigus 10.4
18 posterior scleritis 10.3 TNF PRTN3
19 arthus reaction 10.3 TNF ELANE
20 periodontosis 10.3 TNF ELANE
21 geographic tongue 10.3 TNF IL36RN
22 netherton syndrome 10.3 PI3 ELANE
23 pyoderma 10.3 TNF IL36RN
24 exanthem 10.3
25 pemphigus vegetans 10.3
26 granulomatosis with polyangiitis 10.3 SERPINB1 PRTN3 ELANE
27 bacterial sepsis 10.2 TNF ELANE
28 middle ear disease 10.2 TNF PRTN3
29 primary hypomagnesemia 10.2 PTH IL36RN
30 churg-strauss syndrome 10.2 TNF PRTN3
31 pustulosis palmaris et plantaris 10.1 TNF IL36RN ELANE
32 palindromic rheumatism 10.1 TNF PRTN3
33 farmer's lung 10.1 TNF PI3 ELANE
34 erysipelas 10.1 TNF PI3 ELANE
35 acute respiratory distress syndrome 10.1 TNF PI3 ELANE
36 mycosis fungoides 10.1
37 intrahepatic cholestasis of pregnancy 10.1
38 dermatomyositis 10.1
39 bacterial infectious disease 10.1
40 rickets 10.1
41 hyperparathyroidism 10.1
42 cholestasis 10.1
43 lymphadenitis 10.1
44 ichthyosis 10.1
45 systemic scleroderma 10.1
46 subacute delirium 10.1
47 lupus erythematosus 10.1
48 lichen disease 10.1 TNF DST
49 pasteurellosis 10.1 ELANE ALB
50 pulmonary disease, chronic obstructive 10.1 TNF SERPINB1 ELANE

Graphical network of the top 20 diseases related to Impetigo Herpetiformis:



Diseases related to Impetigo Herpetiformis

Symptoms & Phenotypes for Impetigo Herpetiformis

MGI Mouse Phenotypes related to Impetigo Herpetiformis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.56 ELANE IL1RL2 IL36RN NLRP1 PRTN3 PTH
2 immune system MP:0005387 9.23 ELANE IL1RL2 IL36RN NLRP1 PRTN3 PTH

Drugs & Therapeutics for Impetigo Herpetiformis

Search Clinical Trials , NIH Clinical Center for Impetigo Herpetiformis

Genetic Tests for Impetigo Herpetiformis

Anatomical Context for Impetigo Herpetiformis

MalaCards organs/tissues related to Impetigo Herpetiformis:

41
Skin, Monocytes, Thyroid

Publications for Impetigo Herpetiformis

Articles related to Impetigo Herpetiformis:

(show top 50) (show all 169)
# Title Authors PMID Year
1
Impetigo herpetiformis responsive to secukinumab. 38
31361940 2019
2
Treatment resistant impetigo herpetiformis treated with infliximab. 38
30693621 2019
3
An effective and promising treatment with adalimumab for impetigo herpetiformis with postpartum flare-up. 38
30028004 2019
4
Generalized pustular psoriasis: a review and update on treatment. 38
29573491 2018
5
Granulocyte/Monocyte Adsorption Apheresis as a Novel Therapeutic Approach in the Treatment of an Impetigo Herpetiformis Case. 38
29318775 2018
6
Impetigo herpetiformis with IL-36RN mutation successfully treated with secukinumab. 38
30105995 2018
7
Autoinflammatory keratinization diseases: An emerging concept encompassing various inflammatory keratinization disorders of the skin. 38
29422292 2018
8
A case of pustular psoriasis of pregnancy with positive maternal-fetal outcomes. 38
29763478 2018
9
Impetigo Herpetiformis: Review of Pathogenesis, Complication, and Treatment. 38
29849579 2018
10
Impetigo herpetiformis: a rare dermotosis of pregnancy. 38
30637058 2018
11
[Impetigo herpetiformis]. 38
30657292 2017
12
Impetigo Herpetiformis Complicated with Intrauterine Growth Restriction Treated Successfully with Granulocyte and Monocyte Apheresis. 38
27573023 2017
13
Recurrent impetigo herpetiformis: case report. 38
28979621 2017
14
Oral and vulvovaginal changes in pregnancy. 38
27265073 2016
15
Inflammatory and glandular skin disease in pregnancy. 38
27265071 2016
16
Skin disease in pregnancy: The approach of the obstetric medicine physician. 38
27265069 2016
17
Inadvertent pregnancy during ustekinumab therapy in a patient with plaque psoriasis and impetigo herpetiformis. 38
25413895 2016
18
Impetigo herpetiformis with IL36RN mutations in a Chinese patient: A founder haplotype of c.115+6T>C in East Asia. 38
26104679 2015
19
[Pregnancy-specific dermatoses]. 38
25194221 2015
20
Case report of a rare dermatosis in pregnancy: impetigo herpetiformis. 38
25303404 2015
21
Psoriasis in pregnancy: challenges and solutions. 38
29387585 2015
22
IL36RN mutations underlie impetigo herpetiformis. 38
24717243 2014
23
Pustular psoriasis of pregnancy (impetigo herpetiformis)--case report. 38
24346915 2013
24
Anesthetic management for cesarean delivery of a parturient with impetigo herpetiformis. 38
25611605 2013
25
Cyclosporine in the management of impetigo herpetiformis: a case report and review of the literature. 38
23626548 2013
26
Impetigo Herpetiformis during pregnancy: a case report and literature review. 38
23446290 2013
27
Recurrent postpartum impetigo herpetiformis presenting after a "skip" pregnancy. 38
22854922 2013
28
[What's new in dermatology?]. 38
23316658 2012
29
A case of recurrent impetigo herpetiformis treated with systemic corticosteroids and narrowband UVB. 38
22264139 2012
30
Shape and configuration of skin lesions: grouped herpetiform. 38
21855726 2011
31
[Pustular eruption of pregnancy: Impetigo herpetiformis]. 38
21334846 2011
32
Recurrent impetigo herpetiformis successfully treated with methotrexate: a case report. 38
21159049 2011
33
First trimester impetigo herpetiformis in multiparous female successfully treated with oral cyclosporine. 38
22696729 2011
34
Pregnancy dermatoses: diagnosis, management, and controversies. 38
21110524 2011
35
Impetigo herpetiformis with gestational hypertension: a case report and literature review. 38
21494028 2011
36
Ritodrine-induced pustular eruptions distinctly resembling impetigo herpetiformis. 38
22041881 2011
37
[Chronic inflammatory and autoimmune mediated dermatoses during pregnancy. Course and prognosis for mother and child]. 38
21076804 2010
38
Recurrent impetigo herpetiformis with diabetes and hypoalbuminemia successfully treated with cyclosporine, albumin, insulin and metformin. 38
20606891 2010
39
Treatment of psoriasis with anti-TNF drugs during pregnancy: case report and review of the literature. 38
19940453 2010
40
Impetigo herpetiformis during the puerperium triggered by secondary hypoparathyroidism: a case report. 38
20072676 2009
41
Impetigo herpetiformis: a rare dermatosis of pregnancy. 38
19864978 2009
42
Impetigo herpetiformis with postpartum flare-up: a case report. 38
19588063 2009
43
Postpartum impetigo herpetiformis complicated with hypovolaemic shock. 38
19521302 2009
44
Recurrent impetigo herpetiformis successfully treated with methotrexate. 38
18554218 2009
45
[Impetigo herpetiformis (two cases)]. 38
18657371 2008
46
Impetigo herpetiformis occurring during N-butyl-scopolammonium bromide therapy in pregnancy: case report. 38
18597707 2008
47
An update on the dermatoses of pregnancy. 38
18390233 2008
48
[How I explore...pruritus in a pregnant woman]. 38
18286948 2007
49
Anaesthesia for caesarean section in a patient with acute generalised pustular psoriasis. 38
17643975 2007
50
Third-trimester impetigo herpetiformis treated with cyclosporine. 38
17224395 2007

Variations for Impetigo Herpetiformis

Expression for Impetigo Herpetiformis

Search GEO for disease gene expression data for Impetigo Herpetiformis.

Pathways for Impetigo Herpetiformis

Pathways related to Impetigo Herpetiformis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.66 PRTN3 PI3 ELANE
2
Show member pathways
11.38 TNF IL36RN IL1RL2
3 9.97 TNF NLRP1

GO Terms for Impetigo Herpetiformis

Cellular components related to Impetigo Herpetiformis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.5 TNF SERPINB1 PTH PRTN3 IL36RN ELANE
2 extracellular region GO:0005576 9.23 TNF SERPINB1 PTH PRTN3 PI3 IL36RN

Biological processes related to Impetigo Herpetiformis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.67 TNF NLRP1 IL36RN IL1RL2
2 cytokine-mediated signaling pathway GO:0019221 9.56 TNF PRTN3 IL36RN IL1RL2
3 negative regulation of interleukin-6 production GO:0032715 9.43 TNF IL36RN
4 negative regulation of growth of symbiont in host GO:0044130 9.4 TNF ELANE
5 regulation of inflammatory response GO:0050727 9.33 TNF NLRP1 IL1RL2
6 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.32 TNF ELANE
7 positive regulation of interleukin-6 production GO:0032755 9.13 TNF IL36RN IL1RL2
8 antimicrobial humoral response GO:0019730 8.8 PRTN3 PI3 ELANE

Sources for Impetigo Herpetiformis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....