MCID: IMP006
MIFTS: 41

Impulse Control Disorder

Categories: Mental diseases

Aliases & Classifications for Impulse Control Disorder

MalaCards integrated aliases for Impulse Control Disorder:

Name: Impulse Control Disorder 12 15
Disruptive, Impulse Control, and Conduct Disorders 44 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10937
ICD10 33 F63.9
ICD9CM 35 312.30
MeSH 44 D007174
NCIt 50 C34723
SNOMED-CT 68 66347000
UMLS 73 C0021122

Summaries for Impulse Control Disorder

Disease Ontology : 12 A disease of mental health that involves a failure to resist an impulsive act or behaviour that may be harmful to self or others.

MalaCards based summary : Impulse Control Disorder, also known as disruptive, impulse control, and conduct disorders, is related to trichotillomania and oppositional defiant disorder. An important gene associated with Impulse Control Disorder is ANKK1 (Ankyrin Repeat And Kinase Domain Containing 1), and among its related pathways/superpathways are Dopamine-DARPP32 Feedback onto cAMP Pathway and Circadian rythm related genes. The drugs Methylphenidate and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and skin, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 76 Impulse-control disorder (ICD) is a class of psychiatric disorders characterized by impulsivity �??... more...

Related Diseases for Impulse Control Disorder

Diseases related to Impulse Control Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 64)
# Related Disease Score Top Affiliating Genes
1 trichotillomania 32.0 SLITRK1 DLGAP3 CLNK
2 oppositional defiant disorder 32.0 DRD4 DRD2
3 pathological gambling 31.9 DRD4 DRD3 DRD2
4 gilles de la tourette syndrome 29.8 SLITRK1 DRD4 DRD2
5 alexithymia 29.8 DRD2 ANKK1
6 substance abuse 29.5 DRD4 DRD3 DRD2
7 obsessive-compulsive disorder 29.5 SLITRK1 DRD4 DRD3 DRD2 DLGAP3
8 kleptomania 11.5
9 pyromania 11.2
10 intermittent explosive disorder 11.0
11 kluver-bucy syndrome 11.0
12 parkinson disease, late-onset 10.2
13 restless legs syndrome 10.1
14 telogen effluvium 10.1 SLITRK1 DLGAP3
15 stereotypic movement disorder 10.1 SLITRK1 CLNK
16 follicular mucinosis 10.1 SLITRK1 DLGAP3
17 taqi polymorphism 10.1 DRD2 ANKK1
18 antisocial personality disorder 10.0 DRD2 ANKK1
19 depression 10.0
20 polysubstance abuse 10.0 DRD3 DRD2
21 tardive dyskinesia 10.0 DRD3 DRD2
22 heroin dependence 10.0 DRD4 DRD2 ANKK1
23 bruxism 10.0 DRD3 DRD2
24 personality disorder 10.0 DRD4 DRD2 ANKK1
25 tic disorder 10.0 SLITRK1 DRD4 DRD2
26 conduct disorder 9.9 DRD4 DRD2
27 opiate dependence 9.9 DRD3 DRD2
28 supranuclear palsy, progressive, 1 9.9 GRN DRD2
29 cocaine dependence 9.9 DRD3 DRD2
30 drug dependence 9.9 DRD3 DRD2 ANKK1
31 delusional disorder 9.9 DRD4 DRD3 DRD2
32 migraine without aura 9.9 DRD4 DRD3 DRD2
33 substance dependence 9.9 DRD4 DRD3 DRD2
34 mood disorder 9.9 DRD4 DRD3 DRD2
35 psychotic disorder 9.9 DRD4 DRD3 DRD2
36 major depressive disorder 9.8 DRD4 DRD3 DRD2
37 perry syndrome 9.8
38 tobacco addiction 9.8
39 dystonia 3, torsion, x-linked 9.8
40 frontotemporal dementia 9.8
41 pituitary adenoma, prolactin-secreting 9.8
42 smoking as a quantitative trait locus 3 9.8
43 bipolar disorder 9.8
44 burns 9.8
45 withdrawal disorder 9.8
46 basal ganglia calcification 9.8
47 stuttering 9.8
48 social phobia 9.8
49 dementia 9.8
50 premature ejaculation 9.8

Comorbidity relations with Impulse Control Disorder via Phenotypic Disease Network (PDN):


Schizophreniform Disorder

Graphical network of the top 20 diseases related to Impulse Control Disorder:



Diseases related to Impulse Control Disorder

Symptoms & Phenotypes for Impulse Control Disorder

GenomeRNAi Phenotypes related to Impulse Control Disorder according to GeneCards Suite gene sharing:

26 (show all 17)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-126 9.6 DRD4
2 Increased shRNA abundance (Z-score > 2) GR00366-A-127 9.6 DRD4
3 Increased shRNA abundance (Z-score > 2) GR00366-A-132 9.6 CLNK DRD3 DRD4
4 Increased shRNA abundance (Z-score > 2) GR00366-A-137 9.6 DRD3
5 Increased shRNA abundance (Z-score > 2) GR00366-A-158 9.6 CLNK
6 Increased shRNA abundance (Z-score > 2) GR00366-A-159 9.6 DRD3
7 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.6 DRD3
8 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.6 DRD3
9 Increased shRNA abundance (Z-score > 2) GR00366-A-172 9.6 DRD4
10 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.6 CLNK
11 Increased shRNA abundance (Z-score > 2) GR00366-A-35 9.6 DRD3
12 Increased shRNA abundance (Z-score > 2) GR00366-A-51 9.6 DRD3
13 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.6 CLNK
14 Increased shRNA abundance (Z-score > 2) GR00366-A-56 9.6 DRD4
15 Increased shRNA abundance (Z-score > 2) GR00366-A-67 9.6 DRD3
16 Increased shRNA abundance (Z-score > 2) GR00366-A-8 9.6 CLNK
17 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.6 DRD3

Drugs & Therapeutics for Impulse Control Disorder

Drugs for Impulse Control Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 89)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
2
Dopamine Approved Phase 4,Phase 3,Phase 2,Not Applicable 51-61-6, 62-31-7 681
3
Nicotine Approved Phase 4 54-11-5 942 89594
4
Topiramate Approved Phase 4 97240-79-4 5284627
5
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 16590-41-3 5360515
6
Ropinirole Approved, Investigational Phase 4 91374-21-9, 91374-20-8 497540 5095
7
Pramipexole Approved, Investigational Phase 4 104632-26-0 119570 59868
8
Levodopa Approved Phase 4,Phase 3 59-92-7 6047
9
Carbidopa Approved Phase 4 28860-95-9 34359 38101
10
Sertraline Approved Phase 4 79617-96-2 68617
11
Citalopram Approved Phase 4 59729-33-8 2771
12
Acamprosate Approved, Investigational Phase 4 77337-76-9 71158
13
Ethanol Approved Phase 4,Phase 2 64-17-5 702
14
Selegiline Approved, Investigational, Vet_approved Phase 4 14611-51-9 26757 5195
15
Varenicline Approved, Investigational Phase 4 249296-44-4 5310966
16 Central Nervous System Stimulants Phase 4
17 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
18 Neurotransmitter Uptake Inhibitors Phase 4
19 Dopamine Uptake Inhibitors Phase 4
20 Dopamine Agents Phase 4,Phase 3,Phase 2,Not Applicable
21 Nicotinic Agonists Phase 4
22 Cholinergic Agents Phase 4
23 Autonomic Agents Phase 4,Phase 3,Phase 2
24 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
25 Anti-Obesity Agents Phase 4
26 Anticonvulsants Phase 4,Phase 2
27 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
28 Neuroprotective Agents Phase 4
29 Narcotic Antagonists Phase 4,Phase 3,Phase 2
30 Narcotics Phase 4,Phase 3,Phase 2
31 Dopamine agonists Phase 4,Phase 3,Phase 2,Not Applicable
32 Sympathomimetics Phase 4,Phase 3
33 Aromatic Amino Acid Decarboxylase Inhibitors Phase 4
34 Antiparkinson Agents Phase 4,Phase 3,Phase 2
35 Cardiotonic Agents Phase 4,Phase 3
36 Serotonin Agents Phase 4,Phase 3
37 Psychotropic Drugs Phase 4,Phase 3
38 Antidepressive Agents Phase 4
39 Serotonin Uptake Inhibitors Phase 4
40 Antidepressive Agents, Second-Generation Phase 4
41 Parasympatholytics Phase 4
42 Cholinergic Antagonists Phase 4
43 Muscarinic Antagonists Phase 4
44 Monoamine Oxidase Inhibitors Phase 4
45 Antioxidants Phase 4,Phase 3,Phase 2,Phase 1
46
Serotonin Investigational, Nutraceutical Phase 4,Phase 3 50-67-9 5202
47
Rotigotine Approved Phase 3,Phase 2 99755-59-6, 92206-54-7 57537
48
Risperidone Approved, Investigational Phase 3 106266-06-2 5073
49
Acetylcysteine Approved, Investigational Phase 3,Phase 2,Phase 1 616-91-1 12035
50
Cabergoline Approved Phase 3 81409-90-7 54746

Interventional clinical trials:

(show all 50)
# Name Status NCT ID Phase Drugs
1 Methylphenidate in ADHD With Trichotillomania Unknown status NCT00552266 Phase 4 Methylphenidate
2 Nicotine Treatment of Impulsivity in Parkinson's Disease Unknown status NCT01216904 Phase 4 nicotine patch;placebo
3 Topiramate in the Treatment of Pathological Gambling Unknown status NCT00245583 Phase 4 topiramate (Topomax)
4 Naltrexone for Impulse Control Disorders in Parkinson's Disease Completed NCT01052831 Phase 4 Naltrexone;Placebo
5 Remission of ICD by Switching Dopamine Agonist to Levodopa/Carbidopa Completed NCT01683253 Phase 4 Levodopa/Carbidopa(200mg/50mg);Dopaminergic Agonists
6 Sertraline and Habit Reversal in the Treatment of Patients With Trichotillomania Completed NCT00118014 Phase 4 Sertraline
7 Escitalopram for the Treatment of Self-Injurious Skin Picking Completed NCT00115011 Phase 4 Escitalopram
8 Acamprosate in the Treatment of Pathological Gambling Completed NCT00571103 Phase 4 acamprosate
9 Efficacy of Orally Disintegrating Selegiline in Parkinson's Patients Experiencing Adverse Effects With Dopamine Agonists Completed NCT00443872 Phase 4 orally disintegrating selegiline (Zelapar)
10 Study of (Mirapex) Pramipexole for the Early Treatment of Parkinsons Disease (PD) Completed NCT00321854 Phase 4 pramipexole
11 Safety And Efficacy Of 12 Weeks Of Varenicline For Smoking Cessation In Smokers With Depression Completed NCT01078298 Phase 4 varenicline;placebo
12 Drug Treatment for Pathologic Gambling Disorder Completed NCT00053677 Phase 3 Naltrexone;Placebo
13 A Long-Term Extension Trial From of SPM 962 in Advanced Parkinson's Disease Patients Completed NCT01631825 Phase 3 SPM 962
14 Study to Determine Whether There Are Any Cognitive or Motor Effects From Taking the Medicine Risperidone. Completed NCT00399698 Phase 3 Risperdal
15 Twelve Month Safety and Efficacy Study of CVT-301 In Parkinson's Disease Patients With OFF Episodes Completed NCT02242487 Phase 3 CVT-301
16 Study of the Efficacy of N-acetylcysteine (NAC) on Impulse Control Disorders Recruiting NCT03146130 Phase 3
17 Dopamine Agonist Treatment of Non-functioning Pituitary Adenomas Recruiting NCT02288962 Phase 3 cabergoline
18 Evaluation of Nalmefene in Impulse Control Disorders in Parkinson's Disease: A Prospective Open Label Study Unknown status NCT02934919 Phase 2 Nalmefene
19 Testing a New Therapy for Trichotillomania Unknown status NCT00872742 Phase 2
20 Investigating the Microstructural and Functional Alterations of Brain in Parkinson's Disease Patients Completed NCT02599753 Phase 2 18-FDTBZ
21 Double-Blind Naltrexone in Compulsive Sexual Behavior Completed NCT00467558 Phase 2 Naltrexone;Sugar pill
22 Imaging Non-motor Symptoms of Parkinson's Disease by Novel 18F-DTBZ and Florbetapir F-18 PET Completed NCT02039024 Phase 2 18F- DTBZ
23 N-Acetyl Cysteine in Pathologic Skin Picking Completed NCT01063348 Phase 2 N-Acetyl Cysteine;Placebo
24 Inositol in Trichotillomania Completed NCT01875445 Phase 2 Inositol;Placebo
25 A Long-Term Extension Trial From Late Phase II of SPM 962 in Patients With Restless Legs Syndrome Completed NCT01562743 Phase 2 SPM 962
26 The Use of Rotigotine for Treatment of Reducing Signs and Symptoms of Fibromyalgia in Adults. Completed NCT00464737 Phase 2 Rotigotine;Rotigotine
27 VY-AADC02 for Parkinson's Disease With Motor Fluctuations Recruiting NCT03562494 Phase 2
28 Randomized Trial Assessing Quinagolide Vaginal Ring for Endometriosis-related Pain Recruiting NCT03692403 Phase 2 Quinagolide 360 µg;Quinagolide 720 µg;Quinagolide 1080 µg;Placebo
29 A Study of Tolerability and Efficacy of Cannabidiol on Tremor in Parkinson's Disease Recruiting NCT02818777 Phase 2 cannabidiol;placebo
30 A Study of Tolerability and Efficacy of Cannabidiol on Motor Symptoms in Parkinson's Disease Recruiting NCT03582137 Phase 2 Cannabidiol
31 Study of Clonidine Efficacy for the Treatment of Impulse Control Disorders in Parkinson's Disease: Not yet recruiting NCT03552068 Phase 2 placebo;Clonidine
32 A Phase 2 Study of CX-8998 in Adults With Tremor Associated With Parkinson's Disease Not yet recruiting NCT03436953 Phase 2 CX-8998;Placebo
33 Effects of the D3 Antagonist GSK598809 on Food Reward and Reinforcement Completed NCT01039454 Phase 1 GSK598809 Capsules;GSK598809 Placebo Capsules
34 Early Study of N-Acetylcysteine to Treat Deliberate Self-Harm in Adolescents Completed NCT01111734 Phase 1 fMRI
35 Exploration of Mesocorticolimbic Pathway in Impulse Control Disorders in Parkinson's Disease: Study Using Tensor Diffusion Imaging and Tractography. Unknown status NCT02796040 Not Applicable
36 Mental Health Related to School Dropout in Luxembourg Unknown status NCT01354236
37 Impulse Control Disorders in Parkinson's Patients Treated With Pramipexole and Other Agents (DOMINION Study) Completed NCT00617019
38 Behavioural Addiction and Genetics in Parkinson's Disease Completed NCT02319395
39 Fingerprinting of Impulsivity Completed NCT02722174
40 fMRI in Impulsivity Completed NCT02755181
41 Exploration of the Reward System by Functional MRI in Parkinson's Disease Patients With and Without REM Sleep Behavior Disorder Completed NCT02824341 Not Applicable
42 Non-interventional Observational Study on the Influence of Pramipexole on Sensory Symptoms of Restless Legs Syndrome (RLS) Completed NCT00887289
43 Motor, Non-motor and Genetic Determinants of Progression in Parkinson's Disease: A Mexican Multicenter Cohort Study Completed NCT01865877
44 Freezing of Gait: Clinical, Cognitive, and Imaging Features Completed NCT02387281
45 Exploration of the Reward System by Functional MRI in Narco-cataplexy Patients With and Without REM Sleep Behavior Disorder Recruiting NCT03425214 Not Applicable
46 Assessment of Apathy in a Real-life Situation, With a Video and Sensors-based System Recruiting NCT03272230 Not Applicable
47 Temporal Relationship Between Motor Fluctuations and Nonmotor Fluctuations Recruiting NCT02060695
48 Cognitive Training in Parkinson Study Recruiting NCT02920632 Not Applicable
49 Effects of Non-invasive Brain Stimulation in Impulse Control Disorders Active, not recruiting NCT02927002 Not Applicable
50 Psychiatric and Cognitive Manifestations of Parkinson's Disease Enrolling by invitation NCT00360633

Search NIH Clinical Center for Impulse Control Disorder

Cochrane evidence based reviews: disruptive, impulse control, and conduct disorders

Genetic Tests for Impulse Control Disorder

Anatomical Context for Impulse Control Disorder

MalaCards organs/tissues related to Impulse Control Disorder:

41
Brain, Cortex, Skin, Liver, Testes, Eye, Prefrontal Cortex

Publications for Impulse Control Disorder

Articles related to Impulse Control Disorder:

(show top 50) (show all 57)
# Title Authors Year
1
Markers of impaired motor and cognitive volition in Parkinson's disease: Correlates of dopamine dysregulation syndrome, impulse control disorder, and dyskinesias. ( 29198499 )
2018
2
Markers of impaired motor and cognitive volition in Parkinson's disease: Correlates of dopamine dysregulation syndrome, impulse control disorder, and dyskinesias. ( 29753604 )
2018
3
Compulsive Sexual Behavior as an Impulse Control Disorder: Awaiting Field Studies Data. ( 29572770 )
2018
4
A 7-year observation of the effect of subthalamic deep brain stimulation on impulse control disorder in patients with Parkinson's disease. ( 30054182 )
2018
5
Sleep in Parkinson's Disease with Impulse Control Disorder. ( 30099617 )
2018
6
Impulse Control Disorder in Parkinson's Disease: A Meta-Analysis of Cognitive, Affective, and Motivational Correlates. ( 30233478 )
2018
7
Behavioural and trait changes in parkinsonian patients with impulse control disorder after switching from dopamine agonist to levodopa therapy: results of REIN-PD trial. ( 30361296 )
2018
8
Disruption of Multiple Distinctive Neural Networks Associated With Impulse Control Disorder in Parkinson's Disease. ( 30519167 )
2018
9
Sleep and REM sleep behaviour disorder in Parkinson's disease with impulse control disorder. ( 29066517 )
2017
10
Cabergoline-related impulse control disorder in an adolescent with a giant prolactinoma. ( 28346715 )
2017
11
Impulse control disorder and response-inhibition alterations in Parkinson's disease. A rare case of totally absent functionality of the medial-prefrontal cortex and review of literature. ( 29034115 )
2017
12
A Multicenter Comparative Study of Impulse Control Disorder in Latin American Patients With Parkinson Disease. ( 28288482 )
2017
13
ISMP Adverse Drug Reactions: Pregabalin-Induced Stuttering Nitroglycerine-Induced Bradycardia Progressing to Asystole Minocycline-Induced DRESS Leading to Liver Transplantation and Type 1 Diabetes Increased Risk of Vertebral Fractures in Women Receiving Thiazide or Loop Diuretics Gambling Disorder and Impulse Control Disorder with Aripiprazole. ( 28515502 )
2017
14
Recurrent Impulse Control Disorder Associated with Rasagiline Treatment of Parkinson's Disease. ( 28767029 )
2017
15
Depression, Impulse Control Disorder, and Life Style According to Smartphone Addiction. ( 29295357 )
2017
16
Electro-acupuncture treatment for internet addiction: Evidence of normalization of impulse control disorder in adolescents. ( 28861803 )
2017
17
Impulse control disorder, lysosomal malfunction and ATP13A2 insufficiency in Parkinsonism. ( 27997702 )
2017
18
Risk of Gambling Disorder and Impulse Control Disorder With Aripiprazole, Pramipexole, and Ropinirole: A Pharmacoepidemiologic Study. ( 27930495 )
2017
19
Psychosis and concurrent impulse control disorder in Parkinson's disease: A review based on a case report. ( 29213446 )
2016
20
Tattooing as a Symptom of Impulse Control Disorder in a Parkinsonian Patient With Pramipexole. ( 27749676 )
2016
21
18F-FDG -PET Correlates of Impulse Control Disorder In A Diabetic Patient. ( 27697074 )
2016
22
Impulse control disorder related behaviours during long-term rotigotine treatment: a post hoc analysis. ( 27425586 )
2016
23
Impulse control disorder in PD: A lateralized monoaminergic frontostriatal disconnection syndrome? ( 27264342 )
2016
24
Association between REM sleep behaviour disorder and impulse control disorder in patients with Parkinson's disease. ( 27087472 )
2016
25
Repetitive urges to inflict burns: An unusual presentation of impulse control disorder. ( 28163418 )
2016
26
Impaired learning of punishments in Parkinson's disease with and without impulse control disorder. ( 27848033 )
2016
27
Incident impulse control disorder symptoms and dopamine transporter imaging in Parkinson disease. ( 26534930 )
2015
28
Impulse control disorder manifesting as hidden sexual self-injury. ( 25828732 )
2015
29
Parkinson's disease treatment may cause impulse-control disorder via dopamine D3 receptors. ( 25645960 )
2015
30
Idiopathic Basal Ganglia Calcification Presented with Impulse Control Disorder. ( 26246920 )
2015
31
Pet killing as a manifestation of impulse control disorder secondary to pramipexol. ( 25768852 )
2015
32
The addiction-related gene ANKK1 in Parkinsonian patients with impulse control disorder. ( 25447970 )
2015
33
Dopamine agonist withdrawal syndrome in a patient with restless legs syndrome without impulse control disorder or drug abuse. ( 25362251 )
2014
34
Impulse control disorder and rapid eye movement sleep behavior disorder in Parkinson's disease. ( 25283069 )
2014
35
Impulse control disorder in patients with Parkinson's disease under dopamine agonist therapy: a multicentre study. ( 24434037 )
2014
36
The role of self-awareness and cognitive dysfunction in Parkinson's disease with and without impulse-control disorder. ( 23686032 )
2013
37
Impulse control disorder in a patient on long-term treatment with bromocriptine for a macroprolactinoma. ( 24045609 )
2013
38
Three cases of impulse control disorder in Parkinson's disease patients receiving dopamine replacement therapy. ( 23472375 )
2013
39
Pathological generosity: An atypical impulse control disorder after a left subcortical stroke. ( 23962063 )
2013
40
Impulse control disorder in a patient with X-linked dystonia-parkinsonism after bilateral pallidal deep brain stimulation. ( 23920134 )
2013
41
Prevalence and pharmacological factors associated with impulse-control disorder symptoms in patients with Parkinson disease. ( 23123689 )
2012
42
Comorbid impulse control disorder in bipolar disorder: the role of antidepressants. ( 22423377 )
2012
43
Zoophilia and impulse control disorder in a patient with Parkinson disease. ( 22057400 )
2012
44
Is premature ejaculation an impulse control disorder? ( 22543077 )
2012
45
Tourette's disease with impulse control disorder. ( 21431012 )
2011
46
Dermatitis artefacta in a patient affected by impulse control disorder: case report. ( 21489363 )
2011
47
Impulse control disorder comorbidity among patients with bipolar I disorder. ( 21683175 )
2011
48
Swallowing foreign bodies as an example of impulse control disorder in a patient with intellectual disabilities: a case report. ( 20941350 )
2010
49
Pathological gambling: an impulse control disorder? Measurement of impulsivity using neurocognitive tests. ( 20803888 )
2010
50
Impulse control disorder and piribedil: report of 5 cases. ( 19959959 )
2010

Variations for Impulse Control Disorder

Expression for Impulse Control Disorder

Search GEO for disease gene expression data for Impulse Control Disorder.

Pathways for Impulse Control Disorder

GO Terms for Impulse Control Disorder

Cellular components related to Impulse Control Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endocytic vesicle GO:0030139 9.32 DRD2 DRD3
2 integral component of postsynaptic density membrane GO:0099061 9.26 DRD3 SLITRK1
3 dopaminergic synapse GO:0098691 9.16 DRD2 DRD3
4 GABA-ergic synapse GO:0098982 9.13 DRD2 DRD3 SLITRK1
5 glutamatergic synapse GO:0098978 9.02 DLGAP3 DRD2 DRD3 DRD4 SLITRK1

Biological processes related to Impulse Control Disorder according to GeneCards Suite gene sharing:

(show all 32)
# Name GO ID Score Top Affiliating Genes
1 synapse assembly GO:0007416 9.65 DRD2 SLITRK1
2 adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO:0007188 9.65 DRD2 DRD3
3 circadian regulation of gene expression GO:0032922 9.65 DRD2 DRD3
4 negative regulation of protein kinase B signaling GO:0051898 9.64 DRD2 DRD3
5 social behavior GO:0035176 9.64 DRD3 DRD4
6 visual learning GO:0008542 9.63 DRD2 DRD3
7 response to cocaine GO:0042220 9.63 DRD2 DRD3
8 positive regulation of cytokinesis GO:0032467 9.62 DRD2 DRD3
9 response to morphine GO:0043278 9.62 DRD2 DRD3
10 adult behavior GO:0030534 9.61 DRD2 SLITRK1
11 negative regulation of blood pressure GO:0045776 9.61 DRD2 DRD3
12 response to amphetamine GO:0001975 9.61 DRD2 DRD3 DRD4
13 adenylate cyclase-activating adrenergic receptor signaling pathway GO:0071880 9.6 DRD2 DRD3
14 synaptic transmission, dopaminergic GO:0001963 9.59 DRD2 DRD3
15 prepulse inhibition GO:0060134 9.58 DRD2 DRD3
16 positive regulation of renal sodium excretion GO:0035815 9.58 DRD2 DRD3
17 arachidonic acid secretion GO:0050482 9.58 DRD2 DRD3 DRD4
18 G protein-coupled receptor internalization GO:0002031 9.57 DRD2 DRD3
19 regulation of postsynaptic neurotransmitter receptor internalization GO:0099149 9.56 DRD3 DRD4
20 behavioral response to ethanol GO:0048149 9.55 DRD2 DRD4
21 negative regulation of voltage-gated calcium channel activity GO:1901386 9.54 DRD2 DRD4
22 behavioral response to cocaine GO:0048148 9.54 DRD2 DRD3 DRD4
23 regulation of dopamine uptake involved in synaptic transmission GO:0051584 9.52 DRD2 DRD3
24 negative regulation of dopamine receptor signaling pathway GO:0060160 9.51 DRD2 DRD3
25 dopamine receptor signaling pathway GO:0007212 9.5 DRD2 DRD3 DRD4
26 acid secretion GO:0046717 9.49 DRD2 DRD3
27 positive regulation of dopamine uptake involved in synaptic transmission GO:0051586 9.48 DRD2 DRD4
28 regulation of locomotion involved in locomotory behavior GO:0090325 9.46 DRD2 DRD3
29 negative regulation of protein secretion GO:0050709 9.43 DRD2 DRD3 DRD4
30 dopamine metabolic process GO:0042417 9.33 DRD2 DRD3 DRD4
31 adenylate cyclase-inhibiting dopamine receptor signaling pathway GO:0007195 9.13 DRD2 DRD3 DRD4
32 response to histamine GO:0034776 8.8 DRD2 DRD3 DRD4

Molecular functions related to Impulse Control Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 drug binding GO:0008144 9.43 DRD2 DRD3 DRD4
2 dopamine binding GO:0035240 9.33 DRD2 DRD3 DRD4
3 adrenergic receptor activity GO:0004935 9.32 DRD2 DRD3
4 dopamine neurotransmitter receptor activity, coupled via Gi/Go GO:0001591 9.13 DRD2 DRD3 DRD4
5 dopamine neurotransmitter receptor activity GO:0004952 8.8 DRD2 DRD3 DRD4

Sources for Impulse Control Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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