MCID: INS022
MIFTS: 30

in Situ Pulmonary Adenocarcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for in Situ Pulmonary Adenocarcinoma

MalaCards integrated aliases for in Situ Pulmonary Adenocarcinoma:

Name: in Situ Pulmonary Adenocarcinoma 12 15
Bronchioloalveolar Adenocarcinoma 73
Bronchioalveolar Carcinoma 12

Classifications:



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Disease Ontology 12 DOID:0050870

Summaries for in Situ Pulmonary Adenocarcinoma

Disease Ontology : 12 A lung cancer that derives from the distal bronchioles or alveoli that initially exhibit a specific non-invasive growth pattern.

MalaCards based summary : in Situ Pulmonary Adenocarcinoma, also known as bronchioloalveolar adenocarcinoma, is related to bronchiolo-alveolar adenocarcinoma and retroperitoneal leiomyosarcoma, and has symptoms including coughing, dyspnea and fever. An important gene associated with in Situ Pulmonary Adenocarcinoma is LINC02288 (Long Intergenic Non-Protein Coding RNA 2288
LncRNAs such as AK124939 may be anticancer factors related to the progression of pulmonary adenocarcinoma
Dysfunction Pattern: Regulation), and among its related pathways/superpathways are Glioma and Pathways in cancer. Affiliated tissues include lung and thyroid, and related phenotypes are homeostasis/metabolism and mortality/aging

Related Diseases for in Situ Pulmonary Adenocarcinoma

Graphical network of the top 20 diseases related to in Situ Pulmonary Adenocarcinoma:



Diseases related to in Situ Pulmonary Adenocarcinoma

Symptoms & Phenotypes for in Situ Pulmonary Adenocarcinoma

UMLS symptoms related to in Situ Pulmonary Adenocarcinoma:


coughing, dyspnea, fever, hemoptysis

MGI Mouse Phenotypes related to in Situ Pulmonary Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.17 ALK ASPH EGFR ESR2 FGF19 HYAL2
2 mortality/aging MP:0010768 10.13 ALK ASPH EGFR ESR2 FGF19 HYAL2
3 neoplasm MP:0002006 9.76 ALK ASPH EGFR ESR2 ITGB1 LYZ
4 nervous system MP:0003631 9.65 ALK EGFR ESR2 FGF19 ITGB1 LYZ
5 no phenotypic analysis MP:0003012 9.17 SLC18A3 EGFR ESR2 HYAL2 IL33 LYZ

Drugs & Therapeutics for in Situ Pulmonary Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for in Situ Pulmonary Adenocarcinoma

Genetic Tests for in Situ Pulmonary Adenocarcinoma

Anatomical Context for in Situ Pulmonary Adenocarcinoma

MalaCards organs/tissues related to in Situ Pulmonary Adenocarcinoma:

41
Lung, Thyroid

Publications for in Situ Pulmonary Adenocarcinoma

Articles related to in Situ Pulmonary Adenocarcinoma:

# Title Authors Year
1
Bronchioloalveolar adenocarcinoma and pulmonary langerhans cell histiocytosis in a patient with MUTYH-associated polyposis. ( 21189386 )
2011
2
A single institution-based retrospective study of surgically treated bronchioloalveolar adenocarcinoma of the lung: clinicopathologic analysis, molecular features, and possible pitfalls in routine practice. ( 20521350 )
2010
3
Expression of Galectin-3, CD138, p16INK4a, and TTF-1 in mucinous bronchioloalveolar adenocarcinoma after Hodgkin lymphoma. ( 18997617 )
2009
4
Usefulness of Cdx2 in separating mucinous bronchioloalveolar adenocarcinoma of the lung from metastatic mucinous colorectal adenocarcinoma. ( 15362373 )
2004
5
Mucinous and nonmucinous bronchioloalveolar adenocarcinomas have distinct staining patterns with thyroid transcription factor and cytokeratin 20 antibodies. ( 11554157 )
2001

Variations for in Situ Pulmonary Adenocarcinoma

Expression for in Situ Pulmonary Adenocarcinoma

Search GEO for disease gene expression data for in Situ Pulmonary Adenocarcinoma.

Pathways for in Situ Pulmonary Adenocarcinoma

GO Terms for in Situ Pulmonary Adenocarcinoma

Cellular components related to in Situ Pulmonary Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 AP-2 adaptor complex GO:0030122 8.62 EGFR SLC18A3

Biological processes related to in Situ Pulmonary Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 viral entry into host cell GO:0046718 9.13 EGFR HYAL2 ITGB1
2 positive regulation of inflammatory response GO:0050729 8.92 EGFR HYAL2 IL33 S100A9

Molecular functions related to in Situ Pulmonary Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.43 ALK EGFR ESR2 LYZ MSI1 SERPINA1
2 virus receptor activity GO:0001618 8.8 EGFR HYAL2 ITGB1

Sources for in Situ Pulmonary Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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