MCID: INS022
MIFTS: 37

in Situ Pulmonary Adenocarcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for in Situ Pulmonary Adenocarcinoma

MalaCards integrated aliases for in Situ Pulmonary Adenocarcinoma:

Name: in Situ Pulmonary Adenocarcinoma 12 15
Bronchioloalveolar Adenocarcinoma 73
Bronchioalveolar Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050870
UMLS 73 C0007120

Summaries for in Situ Pulmonary Adenocarcinoma

Disease Ontology : 12 A lung cancer that derives from the distal bronchioles or alveoli that initially exhibit a specific non-invasive growth pattern.

MalaCards based summary : in Situ Pulmonary Adenocarcinoma, also known as bronchioloalveolar adenocarcinoma, is related to congenital granular cell tumor and retroperitoneal leiomyosarcoma, and has symptoms including fever, dyspnea and hemoptysis. An important gene associated with in Situ Pulmonary Adenocarcinoma is LINC02288 (Long Intergenic Non-Protein Coding RNA 2288), and among its related pathways/superpathways are Glioma and Pathways in cancer. Affiliated tissues include lung, smooth muscle and kidney, and related phenotypes are homeostasis/metabolism and mortality/aging

Related Diseases for in Situ Pulmonary Adenocarcinoma

Graphical network of the top 20 diseases related to in Situ Pulmonary Adenocarcinoma:



Diseases related to in Situ Pulmonary Adenocarcinoma

Symptoms & Phenotypes for in Situ Pulmonary Adenocarcinoma

UMLS symptoms related to in Situ Pulmonary Adenocarcinoma:


fever, dyspnea, hemoptysis, coughing

MGI Mouse Phenotypes related to in Situ Pulmonary Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.21 ALK ASPH EGFR ESR2 FGF19 HYAL2
2 mortality/aging MP:0010768 10.2 ALK ASPH EGFR ESR2 FGF19 HYAL2
3 neoplasm MP:0002006 9.86 ALK ASPH EGFR ESR2 ITGB1 LYZ
4 nervous system MP:0003631 9.85 ALK EGFR ESR2 FGF19 ITGB1 LYZ
5 no phenotypic analysis MP:0003012 9.5 EGFR ESR2 HYAL2 IL33 LYZ PROM1
6 skeleton MP:0005390 9.23 ALK EGFR ESR2 HYAL2 ITGB1 LYZ

Drugs & Therapeutics for in Situ Pulmonary Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for in Situ Pulmonary Adenocarcinoma

Genetic Tests for in Situ Pulmonary Adenocarcinoma

Anatomical Context for in Situ Pulmonary Adenocarcinoma

MalaCards organs/tissues related to in Situ Pulmonary Adenocarcinoma:

41
Lung, Smooth Muscle, Kidney, Pancreas

Publications for in Situ Pulmonary Adenocarcinoma

Articles related to in Situ Pulmonary Adenocarcinoma:

# Title Authors Year
1
Bronchioloalveolar adenocarcinoma and pulmonary langerhans cell histiocytosis in a patient with MUTYH-associated polyposis. ( 21189386 )
2011
2
A single institution-based retrospective study of surgically treated bronchioloalveolar adenocarcinoma of the lung: clinicopathologic analysis, molecular features, and possible pitfalls in routine practice. ( 20521350 )
2010
3
Usefulness of Cdx2 in separating mucinous bronchioloalveolar adenocarcinoma of the lung from metastatic mucinous colorectal adenocarcinoma. ( 15362373 )
2004
4
Is high-grade adenomatous hyperplasia an early bronchioloalveolar adenocarcinoma? ( 14595748 )
2003
5
Early results of a prospective study of limited resection for bronchioloalveolar adenocarcinoma of the lung. ( 11269483 )
2001
6
Expression of alpha-smooth muscle actin in small bronchioloalveolar adenocarcinoma of the lung: assessment and comparison with noguchi criteria. ( 10523684 )
1999
7
Bronchioloalveolar adenocarcinoma of lung: monoclonal origin for multifocal disease. ( 9808126 )
1998
8
Bronchioloalveolar adenocarcinoma with myoepithelial cells. ( 1849448 )
1991

Variations for in Situ Pulmonary Adenocarcinoma

Expression for in Situ Pulmonary Adenocarcinoma

Search GEO for disease gene expression data for in Situ Pulmonary Adenocarcinoma.

Pathways for in Situ Pulmonary Adenocarcinoma

GO Terms for in Situ Pulmonary Adenocarcinoma

Biological processes related to in Situ Pulmonary Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 viral entry into host cell GO:0046718 9.13 EGFR HYAL2 ITGB1
2 positive regulation of inflammatory response GO:0050729 8.92 EGFR HYAL2 IL33 S100A9

Molecular functions related to in Situ Pulmonary Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.43 ALK EGFR ESR2 LYZ MSI1 SERPINA1
2 virus receptor activity GO:0001618 8.8 EGFR HYAL2 ITGB1

Sources for in Situ Pulmonary Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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