MCID: INC030
MIFTS: 14

Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific

Categories: Genetic diseases

Aliases & Classifications for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

MalaCards integrated aliases for Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific:

Name: Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific 56 29 6 39
Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific 56

Classifications:



External Ids:

OMIM 56 613098

Summaries for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

MalaCards based summary : Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific, is also known as analgesia from kappa-opioid receptor agonist, female-specific. An important gene associated with Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific is MC1R (Melanocortin 1 Receptor). Affiliated tissues include eye and skin.

More information from OMIM: 613098

Related Diseases for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Symptoms & Phenotypes for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Clinical features from OMIM:

613098

Drugs & Therapeutics for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Search Clinical Trials , NIH Clinical Center for Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific

Genetic Tests for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Genetic tests related to Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific:

# Genetic test Affiliating Genes
1 Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific 29 MC1R

Anatomical Context for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

MalaCards organs/tissues related to Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific:

40
Eye, Skin

Publications for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Articles related to Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific:

(show all 11)
# Title Authors PMID Year
1
Is the MC1R variant p.R160W associated with Parkinson's? 6
26389967 2016
2
The MC1R melanoma risk variant p.R160W is associated with Parkinson disease. 6
25631192 2015
3
Susceptibility loci for pigmentation and melanoma in relation to Parkinson's disease. 6
24439955 2014
4
Genetic determinants of hair color and Parkinson's disease risk. 6
19194882 2009
5
Genetic determinants of hair, eye and skin pigmentation in Europeans. 6
17952075 2007
6
Identification of novel functional variants of the melanocortin 1 receptor gene originated from Asians. 6
16463023 2006
7
Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans. 6
15994880 2005
8
MC1R mutations modify the classic phenotype of oculocutaneous albinism type 2 (OCA2). 6
12876664 2003
9
The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans. 56
12663858 2003
10
Melanocortin 1 receptor variants in an Irish population. 6
9665397 1998
11
Human pigmentation phenotype: a point mutation generates nonfunctional MSH receptor. 6
9571181 1998

Variations for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

ClinVar genetic disease variations for Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific:

6 ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 MC1R NM_002386.3(MC1R):c.478C>T (p.Arg160Trp)SNV Conflicting interpretations of pathogenicity 14310 rs1805008 16:89986144-89986144 16:89919736-89919736
2 MC1R NM_002386.3(MC1R):c.451C>T (p.Arg151Cys)SNV Conflicting interpretations of pathogenicity 14312 rs1805007 16:89986117-89986117 16:89919709-89919709
3 MC1R NM_002386.3(MC1R):c.583T>G (p.Phe195Val)SNV Uncertain significance 239157 rs377580634 16:89986249-89986249 16:89919841-89919841
4 MC1R NM_002386.3(MC1R):c.112G>A (p.Val38Met)SNV Uncertain significance 406211 rs200050206 16:89985778-89985778 16:89919370-89919370
5 MC1R NM_002386.3(MC1R):c.104G>A (p.Cys35Tyr)SNV Uncertain significance 430181 rs779504604 16:89985770-89985770 16:89919362-89919362
6 MC1R NM_002386.3(MC1R):c.265G>C (p.Gly89Arg)SNV Uncertain significance 449207 rs34540312 16:89985931-89985931 16:89919523-89919523
7 MC1R NM_002386.3(MC1R):c.332C>T (p.Ala111Val)SNV Uncertain significance 470704 rs201489928 16:89985998-89985998 16:89919590-89919590
8 MC1R NM_002386.3(MC1R):c.766C>T (p.Pro256Ser)SNV Uncertain significance 470711 rs200215218 16:89986432-89986432 16:89920024-89920024

Expression for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Search GEO for disease gene expression data for Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific.

Pathways for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

GO Terms for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Sources for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
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30 HMDB
31 HPO
32 ICD10
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50 NDF-RT
53 NINDS
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56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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