MCID: INC030
MIFTS: 14

Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific

Categories: Genetic diseases

Aliases & Classifications for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

MalaCards integrated aliases for Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific:

Name: Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific 57 29 6
Analgesia, Increased, from Kappa-Opioid Receptor Agonist, Female-Specific 39
Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific 57

Classifications:



External Ids:

OMIM® 57 613098

Summaries for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

MalaCards based summary : Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific, is also known as analgesia, increased, from kappa-opioid receptor agonist, female-specific. An important gene associated with Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific is MC1R (Melanocortin 1 Receptor). Affiliated tissues include eye and skin.

More information from OMIM: 613098

Related Diseases for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Symptoms & Phenotypes for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Clinical features from OMIM®:

613098 (Updated 20-May-2021)

Drugs & Therapeutics for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Search Clinical Trials , NIH Clinical Center for Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific

Genetic Tests for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Genetic tests related to Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific:

# Genetic test Affiliating Genes
1 Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific 29 MC1R

Anatomical Context for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

MalaCards organs/tissues related to Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific:

40
Eye, Skin

Publications for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Articles related to Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific:

(showing 11, show less)
# Title Authors PMID Year
1
Is the MC1R variant p.R160W associated with Parkinson's? 6
26389967 2016
2
The MC1R melanoma risk variant p.R160W is associated with Parkinson disease. 6
25631192 2015
3
Susceptibility loci for pigmentation and melanoma in relation to Parkinson's disease. 6
24439955 2014
4
Genetic determinants of hair color and Parkinson's disease risk. 6
19194882 2009
5
Genetic determinants of hair, eye and skin pigmentation in Europeans. 6
17952075 2007
6
Identification of novel functional variants of the melanocortin 1 receptor gene originated from Asians. 6
16463023 2006
7
Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans. 6
15994880 2005
8
MC1R mutations modify the classic phenotype of oculocutaneous albinism type 2 (OCA2). 6
12876664 2003
9
The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans. 57
12663858 2003
10
Melanocortin 1 receptor variants in an Irish population. 6
9665397 1998
11
Human pigmentation phenotype: a point mutation generates nonfunctional MSH receptor. 6
9571181 1998

Variations for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

ClinVar genetic disease variations for Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific:

6 (showing 8, show less)
# Gene Name Type Significance ClinVarId dbSNP ID Position
1 MC1R NM_002386.3(MC1R):c.478C>T (p.Arg160Trp) SNV Affects 14310 rs1805008 GRCh37: 16:89986144-89986144
GRCh38: 16:89919736-89919736
2 MC1R NM_002386.3(MC1R):c.451C>T (p.Arg151Cys) SNV Affects 14312 rs1805007 GRCh37: 16:89986117-89986117
GRCh38: 16:89919709-89919709
3 MC1R NM_002386.3(MC1R):c.332C>T (p.Ala111Val) SNV Uncertain significance 470704 rs201489928 GRCh37: 16:89985998-89985998
GRCh38: 16:89919590-89919590
4 MC1R NM_002386.3(MC1R):c.583T>G (p.Phe195Val) SNV Uncertain significance 239157 rs377580634 GRCh37: 16:89986249-89986249
GRCh38: 16:89919841-89919841
5 MC1R NM_002386.3(MC1R):c.265G>C (p.Gly89Arg) SNV Uncertain significance 449207 rs34540312 GRCh37: 16:89985931-89985931
GRCh38: 16:89919523-89919523
6 MC1R NM_002386.3(MC1R):c.104G>A (p.Cys35Tyr) SNV Uncertain significance 430181 rs779504604 GRCh37: 16:89985770-89985770
GRCh38: 16:89919362-89919362
7 MC1R NM_002386.3(MC1R):c.766C>T (p.Pro256Ser) SNV Uncertain significance 470711 rs200215218 GRCh37: 16:89986432-89986432
GRCh38: 16:89920024-89920024
8 MC1R NM_002386.3(MC1R):c.112G>A (p.Val38Met) SNV Uncertain significance 406211 rs200050206 GRCh37: 16:89985778-89985778
GRCh38: 16:89919370-89919370

Expression for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Search GEO for disease gene expression data for Increased Analgesia from Kappa-Opioid Receptor Agonist, Female-Specific.

Pathways for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

GO Terms for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

Sources for Increased Analgesia from Kappa-Opioid Receptor Agonist,...

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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