MCID: IND001
MIFTS: 16

Indian Tick Typhus

Categories: Infectious diseases

Aliases & Classifications for Indian Tick Typhus

MalaCards integrated aliases for Indian Tick Typhus:

Name: Indian Tick Typhus 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050042

Summaries for Indian Tick Typhus

Disease Ontology : 12 A spotted fever that has material basis in Rickettsia conorii subsp indica, which is transmitted by ticks (Rhipicephalus sanguineus). The infection has symptom fever, has symptom eschar, has symptom regional adenopathy, and has symptom maculopapular rash on extremities.

MalaCards based summary : Indian Tick Typhus is related to boutonneuse fever and purpura fulminans, and has symptoms including fever, eschar and regional adenopathy. An important gene associated with Indian Tick Typhus is PLEKHG4 (Pleckstrin Homology And RhoGEF Domain Containing G4). Related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Related Diseases for Indian Tick Typhus

Diseases related to Indian Tick Typhus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 boutonneuse fever 11.3
2 purpura fulminans 10.1
3 purpura 10.1
4 myositis 9.9
5 hepatitis 9.9
6 rocky mountain spotted fever 9.9
7 meningoencephalitis 9.9
8 spotted fever 9.9
9 choroiditis 9.9
10 hepatitis a 9.9
11 flinders island spotted fever 9.2 CD40LG PLEKHG4
12 japanese spotted fever 9.0 CD40LG PLEKHG4

Graphical network of the top 20 diseases related to Indian Tick Typhus:



Diseases related to Indian Tick Typhus

Symptoms & Phenotypes for Indian Tick Typhus

Symptoms:

12
  • fever
  • eschar
  • regional adenopathy
  • maculopapular rash on extremities

GenomeRNAi Phenotypes related to Indian Tick Typhus according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.23 CD40LG PLEKHG4
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.23 CD40LG PLEKHG4

Drugs & Therapeutics for Indian Tick Typhus

Search Clinical Trials , NIH Clinical Center for Indian Tick Typhus

Genetic Tests for Indian Tick Typhus

Anatomical Context for Indian Tick Typhus

Publications for Indian Tick Typhus

Articles related to Indian Tick Typhus:

(show all 13)
# Title Authors Year
1
Indian Tick Typhus Presenting as Purpura Fulminans with Review on Rickettsial Infections. ( 28216718 )
2017
2
Bevacizumab in choroidal neovascularization secondary to Indian tick typhus: A rare case report. ( 27905346 )
2016
3
Meningoencephalitis, myositis, and rash-neurological presentation of Indian tick typhus. ( 27365979 )
2016
4
Indian tick typhus presenting with gangrene: a case report from an urban slum of delhi. ( 23783766 )
2014
5
Indian tick typhus - an uncommon cause of hepatitis: a case report. ( 24995203 )
2014
6
Indian tick typhus presenting as Purpura fulminans. ( 25097365 )
2014
7
Genome sequence of Rickettsia conorii subsp. indica, the agent of Indian tick typhus. ( 22628514 )
2012
8
Rickettsia conorii Indian tick typhus strain and R. slovaca in humans, Sicily. ( 22608066 )
2012
9
Indian tick typhus mimicking as Rocky Mountain Spotted Fever: a case report. ( 19127676 )
2008
10
First documentation of Rickettsia conorii infection (strain Indian tick typhus) in a Traveler. ( 11747712 )
2001
11
Cutaneous eruptions in Indian tick typhus. ( 1757181 )
1991
12
The Distribution of Indian Tick Typhus with Notes on Laboratory Findings. ( 29012994 )
1936
13
Indian Tick-Typhus. ( 29010413 )
1925

Variations for Indian Tick Typhus

Expression for Indian Tick Typhus

Search GEO for disease gene expression data for Indian Tick Typhus.

Pathways for Indian Tick Typhus

GO Terms for Indian Tick Typhus

Sources for Indian Tick Typhus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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