MCID: INF021
MIFTS: 31

Infant Gynecomastia

Categories: Fetal diseases

Aliases & Classifications for Infant Gynecomastia

MalaCards integrated aliases for Infant Gynecomastia:

Name: Infant Gynecomastia 12 71
Gynecomastia 43 71
Breast Engorgement in Newborn 12
Neonatal Gynaecomastia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11603
ICD9CM 34 778.7
MeSH 43 D006177
NCIt 49 C117312
SNOMED-CT 67 34831003
ICD10 32 P83.4
UMLS 71 C0018418 C1449721

Summaries for Infant Gynecomastia

Disease Ontology : 12 A breast disease that is characterized by benign proliferation of glandular breast tissue and occurs in children less than one year of age.

MalaCards based summary : Infant Gynecomastia, also known as gynecomastia, is related to gynecomastia and aromatase excess syndrome. The drugs Eplerenone and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include breast, prostate and liver.

Related Diseases for Infant Gynecomastia

Diseases related to Infant Gynecomastia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 342)
# Related Disease Score Top Affiliating Genes
1 gynecomastia 12.8
2 aromatase excess syndrome 12.4
3 wilson-turner x-linked mental retardation syndrome 12.3
4 17-beta hydroxysteroid dehydrogenase iii deficiency 12.3
5 spinal and bulbar muscular atrophy, x-linked 1 11.8
6 hypogonadotropic hypogonadism 11.7
7 androgen insensitivity, partial 11.6
8 androgen insensitivity syndrome 11.5
9 testicular seminoma 11.5
10 borjeson-forssman-lehmann syndrome 11.3
11 46,xx sex reversal 1 11.3
12 mental retardation, x-linked, syndromic, turner type 11.2
13 alopecia, neurologic defects, and endocrinopathy syndrome 11.1
14 48,xxxy syndrome 11.1
15 48,xxyy syndrome 11.1
16 49, xxxxy syndrome 11.1
17 49, xxxyy syndrome 11.1
18 hypogonadism 10.6
19 hypogonadotropism 10.6
20 breast cancer 10.5
21 leydig cell tumor 10.4
22 hyperthyroidism 10.4
23 galactorrhea 10.4
24 hyperprolactinemia 10.4
25 testicular cancer 10.3
26 in situ carcinoma 10.3
27 peutz-jeghers syndrome 10.3
28 ductal carcinoma in situ 10.3
29 breast disease 10.3
30 liver cirrhosis 10.3
31 ptosis 10.3
32 hypospadias 10.3
33 estrogen excess 10.3
34 liver disease 10.3
35 neurofibromatosis, type iv, of riccardi 10.2
36 impotence 10.2
37 pseudohermaphroditism 10.2
38 prostate cancer 10.2
39 leprosy 3 10.2
40 pulmonary tuberculosis 10.2
41 hansen's disease 10.2
42 papilloma 10.2
43 sertoli cell tumor 10.2
44 precocious puberty 10.2
45 lung cancer 10.2
46 mastitis 10.2
47 adrenocortical carcinoma, hereditary 10.1
48 graves disease 1 10.1
49 body mass index quantitative trait locus 1 10.1
50 adrenal cortical carcinoma 10.1

Graphical network of the top 20 diseases related to Infant Gynecomastia:



Diseases related to Infant Gynecomastia

Symptoms & Phenotypes for Infant Gynecomastia

Drugs & Therapeutics for Infant Gynecomastia

Drugs for Infant Gynecomastia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 103)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Eplerenone Approved Phase 4 107724-20-9 150310 443872
2
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
3
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
4
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
5
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
6 Antihypertensive Agents Phase 4
7 Tranquilizing Agents Phase 4
8 Psychotropic Drugs Phase 4
9 Antipsychotic Agents Phase 4
10 Antidepressive Agents Phase 4
11 Quetiapine Fumarate Phase 4 111974-72-2
12 Neurotransmitter Agents Phase 4
13 Dopamine Agents Phase 4
14 Dopamine D2 Receptor Antagonists Phase 4
15 Serotonin 5-HT1 Receptor Agonists Phase 4
16 Serotonin Agents Phase 4
17 Dopamine Antagonists Phase 4
18 Dopamine agonists Phase 4
19 Serotonin 5-HT2 Receptor Antagonists Phase 4
20 Serotonin Antagonists Phase 4
21 Serotonin Receptor Agonists Phase 4
22 Liver Extracts Phase 4
23 Protective Agents Phase 4
24 Anticholesteremic Agents Phase 4
25 Hypolipidemic Agents Phase 4
26 Antioxidants Phase 4
27 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
28 Lipid Regulating Agents Phase 4
29 Antimetabolites Phase 4
30 Central Nervous System Depressants Phase 4
31 Anesthetics, Local Phase 4
32 Anesthetics Phase 4
33
Serotonin Investigational, Nutraceutical Phase 4 50-67-9 5202
34
Anastrozole Approved, Investigational Phase 3 120511-73-1 2187
35
Tamoxifen Approved Phase 3 10540-29-1 2733526
36
Testosterone Approved, Experimental, Investigational Phase 3 58-22-0, 481-30-1 6013 10204
37
Methyltestosterone Approved Phase 3 58-18-4 6010
38
Testosterone undecanoate Approved, Investigational Phase 3 5949-44-0
39
Testosterone enanthate Approved Phase 3 315-37-7 9416
40
Letrozole Approved, Investigational Phase 3 112809-51-5 3902
41
Dutasteride Approved, Investigational Phase 3 164656-23-9 152945 6918296
42
Bicalutamide Approved Phase 3 90357-06-5 56069 2375
43
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
44
Polyestradiol phosphate Approved Phase 3 28014-46-2
45
Flutamide Approved, Investigational Phase 3 13311-84-7 3397
46
Goserelin Approved Phase 3 65807-02-5, 1233494-97-7 47725 5311128
47
Spironolactone Approved Phase 3 1952-01-7, 52-01-7 5833
48
Dihydrotestosterone Illicit, Investigational Phase 3 521-18-6 10635
49 Aromatase Inhibitors Phase 3
50 Steroid Synthesis Inhibitors Phase 3

Interventional clinical trials:

(show all 32)
# Name Status NCT ID Phase Drugs
1 Changes of Heart Rate Variability in Schizophrenic and Bipolar Patients Under the Medication of Aripiprazole and Quetiapine Unknown status NCT01047215 Phase 4 Aripiprazole; Quetiapine
2 Does Aldosterone Cause Hypertension by a Non-Renal Mechanism? Unknown status NCT00553722 Phase 4 Eplerenone;Placebo
3 The Effects of Melatonin on Elevated Liver Enzymes During Statins Treatment Completed NCT03121521 Phase 4 Melatonin 10 mg;Placebo
4 EFFICACY EVALUATION OF PRUNUS DOMESTICA EXTRACT ON BENIGN PROSTATE HYPERPLASIA (BPH): An Add on Study Completed NCT02702947 Phase 4
5 Does Stellate Ganglion Blockade (SGB) in Men Treated for Prostate Cancer Improve Hot Flashes? A Pilot Prospective Cohort Study Recruiting NCT03796195 Phase 4 .5% Bupivacaine
6 An OptioExtension of Trial 1033US/0006 to Assess Safety, Tolerability, Efficacy of Anastrozole (ZD1033, Arimidex™) in Treatment of Gynecomastia in Pubertal Boys Given Placebo and to Conduct a Long-Term Safety Follow-Up of Non-Responding Subjects Given Anastrozole in the Previous Trial Completed NCT00637182 Phase 3 Anastrozole
7 A Comparative Trial of the Efficacy of Two Different Nolvadex (NDX) Dosing and Scheduling Regimens in Preventing Gynecomastia Induced by Casodex (CDX) 150 Monotherapy in Prostate Cancer Patients. An Open, Multicenter, Phase III Trial. Completed NCT00233610 Phase 3 Bicalutamide;Tamoxifen
8 Role of Testosterone and Its Metabolites Regarding Different Physiological Functions in Subjects Affected by Gender Identity Disorder (FtM Transsexuals) Completed NCT00146146 Phase 3 testosterone undecanoate alone;testosterone undecanoate plus letrozole;testosterone undecanoate plus dutasteride
9 A Randomized-Controlled Trial of Transcutaneous Oestrogen Patches Versus LHRH Agonists in Prostate Cancer Recruiting NCT00303784 Phase 3 Goserelin;Estradiol
10 Usefulness of Spironolactone for the Prevention of Acute Kidney Injury in Critically Ill Patients With Invasive Mechanical Ventilation Not yet recruiting NCT03206658 Phase 3 Spironolactone 25 mg;Placebo oral capsule
11 An Open-Label Pharmacokinetic and Pharmacodynamic Study of Anastrozole (Arimidex™) Used to Treat Pubertal Boys With Gynecomastia of Recent Onset Completed NCT00241436 Phase 2 Anastrozole (ARIMIDEX™)
12 Randomised, Double-blind, Placebo Controlled, Parallel-group, Multicentre Phase II Study to Assess Dose Response Relationship of Nolvadex (Oral Tablet) in Prophylactic Treatment of Gynaecomastia and Breast Pain Associated With CASODEX 150 mg (Oral Tablet), and to Assess the Tumour Control….. Completed NCT00637871 Phase 2 Casodex;Tamoxifen
13 Spironolactone and Testolactone Treatment of Boys With Familial Isosexual Precocious Puberty Completed NCT00001202 Phase 2 Spironolactone;Testolactone;Deslorelin
14 5-Alpha Reductase and Anabolic Effects of Testosterone Completed NCT00475501 Phase 2 Testosterone Enanthate;Finasteride
15 Open-label Study on Treatment of Primary Aldosteronism With Everolimus Completed NCT03174171 Phase 2 Everolimus 0.75 mg
16 Phase II, Open Label, Dose Finding Study of the Effect of GTx-758 on Total and Free Testosterone Levels in Men With Prostate Cancer Compared to a Luteinizing Hormone Releasing Hormone Agonist Terminated NCT01326312 Phase 2 GTx-758;Lupron Depot;GTx-758
17 A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study of BHR-200 (0.36% Transdermal Estradiol Gel) for the Maintenance of Testosterone Suppression in Men With Advanced Androgen-Sensitive Prostate Cancer Terminated NCT02349386 Phase 2 BHR-200 (0.36% transdermal 17β-estradiol gel);Placebo
18 Transplantation of Expanded and Unexpanded Umbilical Cord Blood Units Following Myeloablative Chemotherapy for Hematologic Malignancies Terminated NCT00539656 Phase 1, Phase 2
19 A Randomized, Double-Blind Placebo-Controlled Study of 3,5-diiodothyropropionic Acid (DITPA) in Combination With Standard Therapy to Attain NCEP ATP III Goal for LDL Cholesterol in Hypercholesterolemic Patients Terminated NCT00311987 Phase 1, Phase 2 3,5-Diiodothyropropionic acid (DITPA) therapy
20 Swedish, Multicentered, Randomized Study of Eplerenone Versus Spironolactone as Treatment of Ascites Due to Liver Cirrhosis Regarding Efficacy and Side Effects Withdrawn NCT01801228 Phase 2 Eplerenone
21 A Randomized Open Label Trial of Spironolactone Versus Prednisolone in Corticosteroid-naïve Boys With DMD Recruiting NCT03777319 Phase 1 Spironolactone;Prednisolone
22 Targeted Fat Reduction of Pseudogynecomastia in the Male Breast Using the ZELTIQ Coolsculpting System Unknown status NCT01791660
23 Effect of Type and Severity of Liver Cirrhosis on Semen Parameters and Reproductive Hormones Unknown status NCT03167749
24 Post-massive Weight Loss Chest Contouring: Inferior Pedicle Technique in Pseudo-gynecomastia Correction Completed NCT03319862
25 A Randomized Controlled Trial Modified Benelli Procedure For Subcutaneous Mastectomy In Gynecomastia Completed NCT04063722
26 Adaptation Among Adolescents and Adults With Klinefelter Syndrome Completed NCT00896272
27 Changes in Hyperprolactinemia Secondary to Antipsychotics After Switching to Quetiapine: a Naturalistic, Prospective, Multicentric Observational Study of 6 Months Follow-up Completed NCT00952757
28 Delayed Puberty in Boys; Clinical and Biochemical Characteristics and Effect of Testosterone Treatment - Retrospective Experience From a Single Tertiary Referral Centre 1990-2013 Completed NCT02034487
29 Management of Azoospermic Patients With Kleinfelter Syndrome Patients With Mesenchymal Stem Cell Injection Completed NCT02414295 Mesenchymal stem cell injection
30 Spironolactone for Reducing Proteinuria in Diabetic Nephropathy Completed NCT00498537 spironolactone
31 Impact of Strength Training With Vascular Occlusion on the Syndrome Lipodystrophy in Patients Harboring With HIV/Aids Terminated NCT02783417
32 Clinical Evaluation of the UltraShape Device for Non-Invasive Fat Reduction in the Male Breast (Pseudogynecomastia) Withdrawn NCT02711605

Search NIH Clinical Center for Infant Gynecomastia

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Tamoxifen
Tamoxifen Citrate

Cochrane evidence based reviews: gynecomastia

Genetic Tests for Infant Gynecomastia

Anatomical Context for Infant Gynecomastia

MalaCards organs/tissues related to Infant Gynecomastia:

40
Breast, Prostate, Liver, Heart, Testis, Pituitary, Lung

Publications for Infant Gynecomastia

Articles related to Infant Gynecomastia:

(show top 50) (show all 3081)
# Title Authors PMID Year
1
Review of the microdebrider excision and liposuction technique (MELT) for the treatment of gynecomastia. 61
31672463 2020
2
Radiation Therapy for Benign Disease: Arteriovenous Malformations, Desmoid Tumor, Dupuytren Contracture, Graves Ophthalmopathy, Gynecomastia, Heterotopic Ossification, Histiocytosis. 61
31739945 2020
3
Bilateral gynecomastia secundary to extramedular plasmocytoma. 61
31928981 2020
4
Sex hormone profile in pubertal boys with gynecomastia and pseudogynecomastia. 61
31996898 2020
5
Gynecomastia after Botulinum Toxin Injections for Poststroke Spasticity. 61
31903667 2020
6
Pseudoangiomatous Stromal Hyperplasia (PASH) of the Breast: An Uncommon Finding in an Uncommon Patient. 61
31941879 2020
7
46,XX male disorder of sexual development. 61
32029971 2020
8
Effectiveness and safety of oral dutasteride for male androgenetic alopecia in real clinical practice: A descriptive monocentric study. 61
31820540 2020
9
Pain, fatigue and depression symptom cluster in survivors of prostate cancer. 61
31980895 2020
10
Frequent testicular involvement in multibacillary leprosy. 61
31634613 2020
11
[A survey of Belgian practice for non-malignant diseases]. 61
31980359 2020
12
The pleura and the endocrine system. 61
31918926 2020
13
Prospective Analysis and Comparison of Periareolar Excision (Delivery) Technique and Pull-Through Technique for the Treatment of Gynecomastia. 61
31989232 2020
14
Combined surgical and medical treatment in an adolescent with severe gynecomastia due to excessive estradiol secretion: a case report. 61
31875785 2019
15
Male Tuberous Breast: A Rare Variant of Gynecomastia. Clinical Considerations and Personal Experience: Tips and Tricks to Maximize Surgical Outcomes. 61
31218378 2019
16
Risk Factors and Treatment Outcomes of 1,375 Patients with Testicular Leydig Cell Tumors: Analysis of Published Case Series Data. 61
31845841 2019
17
Primary aldosteronism in Klinefelter's syndrome: two cases. 61
31841437 2019
18
Gynecomastia Associated With Citalopram. 61
31846239 2019
19
Detection of Nonylphenol with a Gold-Nanoparticle-Based Small-Molecule Sensing System Using an ssDNA Aptamer. 61
31892242 2019
20
A case of Kallmann syndrome associated to a novel missense mutation of the FGFR1 gene. 61
31910188 2019
21
Comparison of curative effects between mammotome-assisted minimally invasive resection (MAMIR) and traditional open surgery for gynecomastia in Chinese patients: A prospective clinical study. 61
31267613 2019
22
Adjustments to the round-the-clock technique for correction of gynecomastia. 61
31775214 2019
23
Response to Letter: Adjustments to the round-the-clock technique for correction of gynecomastia. 61
31775215 2019
24
Modified Benelli procedure for subcutaneous mastectomy in gynecomastia: A randomised controlled trial. 61
31641496 2019
25
Lavender Products Associated With Premature Thelarche and Prepubertal Gynecomastia: Case Reports and Endocrine-Disrupting Chemical Activities. 61
31393563 2019
26
Vacuum-assisted minimally invasive surgery-An innovative method for the operative treatment of gynecomastia. 61
31248653 2019
27
Clinical and Biochemical Phenotype of Adolescent Males with Gynecomastia 61
31117335 2019
28
EAA clinical practice guidelines-gynecomastia evaluation and management. 61
31099174 2019
29
Barriers to the Effective Management of Gynecomastia in Adolescents. 61
31592845 2019
30
Breast Cancer in a 53-year-old Obese Male. 61
31890398 2019
31
Incidental Uptake in Benign Gynecomastia on 68Ga-DOTATATE PET/CT. 61
30985420 2019
32
Idiopathic prepubertal unilateral gynecomastia: Case report and literature review. 61
31577740 2019
33
Liposuction in Gynecomastia: An Assessment of the Suction-assisted Arthroscopic Shaver Versus Open Disc Excision Techniques. 61
31772867 2019
34
Klinefelter's syndrome with systemic lupus erythematosus and atrial fibrillation. 61
31551034 2019
35
Stabilization of Early Duchenne Cardiomyopathy With Aldosterone Inhibition: Results of the Multicenter AIDMD Trial. 61
31549577 2019
36
Indirect clinical markers for the detection of anabolic steroid abuse beyond the conventional doping control in athletes. 61
30880613 2019
37
Trends in Imaging Workup of the Male Breast: Experience from a Single Center. 61
31599508 2019
38
Analysis of Data From Breast Diseases Treated With 5-Alpha Reductase Inhibitors for Benign Prostatic Hyperplasia. 61
31126837 2019
39
Correction of Tuberous Nipple Areolar Complex Deformity in Gynecomastia: The Deformity That Can Get Forgotten. 61
30161048 2019
40
Anabolic-androgenic Steroid Use Among Gynecomastia Patients: Prevalence and Relevance to Surgical Management. 61
31021838 2019
41
Endoscopic Axillary Approach Improves Patient Satisfaction of Gynecomastia Subcutaneous Mastectomy: A Cross-Sectional Study Using the BODY-Q Chest Module. 61
31555872 2019
42
Influence of Postoperative Finasteride Therapy on Recurrence of Gynecomastia After Mastectomy in Men Taking Finasteride for Alopecia. 61
31552775 2019
43
Male Breast Disease: What the Radiologist Needs to Know. 61
30122313 2019
44
Gynecomastia or rare malignancy? A young man with an unremarkable history proves to have adenoid cystic carcinoma of the breast. 61
31493308 2019
45
Reply: Treatment of Severe Gynecomastia after Massive Weight Loss: Analysis of Long-Term Outcomes Measured with the Italian Version of the BODY-Q. 61
31348386 2019
46
Reply: Treatment of Severe Gynecomastia after Massive Weight Loss: Analysis of Long-Term Outcomes Measured with the Italian Version of the BODY-Q. 61
31348388 2019
47
Closed-Suction Drains After Subcutaneous Mastectomy for Gynecomastia: Do they Reduce Complications? 61
29302730 2019
48
Gynecomastia in HIV-positive adult men receiving efavirenz-based antiretroviral therapy at Newlands clinic, Harare, Zimbabwe. 61
31409277 2019
49
Innovative Technique to Improve Chest Shape following Gynecomastia Correction in Post-Bariatric Surgery Patients. 61
31348385 2019
50
Treatment of Gynecomastia by Endoscopic Subcutaneous Mastectomy in Adolescents. 61
31216208 2019

Variations for Infant Gynecomastia

Expression for Infant Gynecomastia

Search GEO for disease gene expression data for Infant Gynecomastia.

Pathways for Infant Gynecomastia

GO Terms for Infant Gynecomastia

Sources for Infant Gynecomastia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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