MCID: INF115
MIFTS: 11

Infectious Epithelial Keratitis

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Infectious Epithelial Keratitis

MalaCards integrated aliases for Infectious Epithelial Keratitis:

Name: Infectious Epithelial Keratitis 58

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases
Orphanet: 58  
Rare eye diseases


External Ids:

Orphanet 58 ORPHA137593

Summaries for Infectious Epithelial Keratitis

MalaCards based summary : Infectious Epithelial Keratitis is related to keratitis, hereditary and blepharoconjunctivitis. The drugs Difluprednate and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include eye.

Related Diseases for Infectious Epithelial Keratitis

Diseases related to Infectious Epithelial Keratitis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 keratitis, hereditary 10.0
2 blepharoconjunctivitis 10.0
3 herpes simplex 10.0
4 blepharitis 10.0

Symptoms & Phenotypes for Infectious Epithelial Keratitis

Drugs & Therapeutics for Infectious Epithelial Keratitis

Drugs for Infectious Epithelial Keratitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Difluprednate Approved Phase 4 23674-86-4 443936
2
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
3
Acyclovir Approved Phase 4 59277-89-3 2022
4 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
5
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
6
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
7
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
8
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
9 Methylprednisolone Acetate Phase 4
10 valacyclovir Phase 4
11 Antiviral Agents Phase 4
12 Ophthalmic Solutions Phase 4
13 Anti-Infective Agents Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized Trial of Topical Corticosteroid Use in Addition to Oral Antivirals for Prevention of Recurrence of Herpes Simplex Virus (HSV) Keratitis Not yet recruiting NCT03626376 Phase 4 oral acyclovir 400 mg BID OR valacyclovir 500 mg qdaily;oral acyclovir 400 mg BID OR valacyclovir 500 mg qdaily + topical corticosteroid eye drops

Search NIH Clinical Center for Infectious Epithelial Keratitis

Genetic Tests for Infectious Epithelial Keratitis

Anatomical Context for Infectious Epithelial Keratitis

MalaCards organs/tissues related to Infectious Epithelial Keratitis:

40
Eye

Publications for Infectious Epithelial Keratitis

Articles related to Infectious Epithelial Keratitis:

# Title Authors PMID Year
1
Development of Herpes Simplex Virus Infectious Epithelial Keratitis During Oral Acyclovir Therapy and Response to Topical Antivirals. 61
26989961 2016
2
Herpes simplex and herpes zoster eye disease: presentation and management at a city hospital for the underserved in the United States. 61
23771014 2013
3
Oral acyclovir for the management of herpes simplex virus keratitis in children. 61
10690825 2000
4
Classification of herpes simplex virus keratitis. 61
10090359 1999

Variations for Infectious Epithelial Keratitis

Expression for Infectious Epithelial Keratitis

Search GEO for disease gene expression data for Infectious Epithelial Keratitis.

Pathways for Infectious Epithelial Keratitis

GO Terms for Infectious Epithelial Keratitis

Sources for Infectious Epithelial Keratitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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