MCID: INF184
MIFTS: 17

Infective Keratitis

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Infective Keratitis

MalaCards integrated aliases for Infective Keratitis:

Name: Infective Keratitis 58

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases
Orphanet: 58  
Rare eye diseases


External Ids:

Orphanet 58 ORPHA519278

Summaries for Infective Keratitis

MalaCards based summary : Infective Keratitis is related to keratitis, hereditary and yemenite deaf-blind hypopigmentation syndrome. The drugs Dexamethasone acetate and Tacrolimus have been mentioned in the context of this disorder. Affiliated tissues include eye and endothelial.

Related Diseases for Infective Keratitis

Diseases related to Infective Keratitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 21)
# Related Disease Score Top Affiliating Genes
1 keratitis, hereditary 10.5
2 yemenite deaf-blind hypopigmentation syndrome 10.1
3 endophthalmitis 10.0
4 corneal ulcer 10.0
5 hypopyon 9.9
6 panophthalmitis 9.9
7 macular dystrophy, corneal 9.8
8 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.8
9 branchiootic syndrome 1 9.8
10 granulomatous amebic encephalitis 9.8
11 corneal disease 9.8
12 chlamydia 9.8
13 corneal abscess 9.8
14 ichthyosis 9.8
15 corneal dystrophy 9.8
16 pneumonia 9.8
17 herpes simplex 9.8
18 mycobacterium chelonae 9.8
19 fungal keratitis 9.8
20 erythrokeratoderma 9.8
21 stromal corneal dystrophy 9.8

Graphical network of the top 20 diseases related to Infective Keratitis:



Diseases related to Infective Keratitis

Symptoms & Phenotypes for Infective Keratitis

Drugs & Therapeutics for Infective Keratitis

Drugs for Infective Keratitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone acetate Approved, Investigational, Vet_approved 1177-87-3
2
Tacrolimus Approved, Investigational 104987-11-3 445643 439492 6473866
3
Dexamethasone Approved, Investigational, Vet_approved 50-02-2 5743
4
Tobramycin Approved, Investigational 32986-56-4 5496 36294
5 Tobramycin, Dexamethasone Drug Combination
6 Pharmaceutical Solutions
7 Anti-Infective Agents
8 Hormone Antagonists
9 Ophthalmic Solutions
10 BB 1101
11 Anti-Inflammatory Agents
12 Immunosuppressive Agents
13 glucocorticoids
14 Anti-Bacterial Agents
15 Calcineurin Inhibitors
16 Immunologic Factors
17 Hormones

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Asia Cornea Society Infectious Keratitis Study Unknown status NCT01560208
2 Prospective Study of Deep Anterior Lamellar Keratoplasty Using Acellular Porcine Cornea Recruiting NCT03105466 Tacrolimus eye drops;Tobradex eyedrops

Search NIH Clinical Center for Infective Keratitis

Genetic Tests for Infective Keratitis

Anatomical Context for Infective Keratitis

MalaCards organs/tissues related to Infective Keratitis:

40
Eye, Endothelial

Publications for Infective Keratitis

Articles related to Infective Keratitis:

(show top 50) (show all 87)
# Title Authors PMID Year
1
Femtosecond Laser-Assisted Penetrating Keratoplasty for Treating Infective Keratitis. 61
31574048 2020
2
Infectious Keratitis Caused by Rare and Emerging Micro-Organisms. 61
31870176 2020
3
Could aflatoxin B1 production by Aspergillus flavus affect the severity of keratitis: an experience in two tertiary health care centers, Egypt. 61
31332609 2019
4
Complications and Explantation Reasons in Intracorneal Ring Segments (ICRS) Implantation: A Systematic Review. 61
31710377 2019
5
Clinical Profile, Etiology, and Outcome of Infantile Ocular Trauma: A Developing Country Perspective. 61
28632575 2019
6
Successful Treatment of Mycobacterium chelonae Keratitis Within a Corneal Transplant Using Intrastromal Amikacin Injections-A Case Report Demonstrating the Fundamental Principles and Challenges of Infective Keratitis Management and Novel Therapeutic Approaches. 61
31660386 2019
7
Microbial Keratitis in Stevens-Johnson Syndrome: A Prospective Study. 61
30998617 2019
8
Causes and Management Outcomes of Acquired Corneal Opacity in a Preschool Age (0-5 Years) Group: A Hospital-Based Study. 61
31045962 2019
9
In vivo confocal microscopy of the inflamed anterior segment: A review of clinical and research applications. 61
30953391 2019
10
Pearls and paradigms in Infective Keratitis. 61
31334389 2019
11
Interferon Alfa 2b for Ocular Surface Squamous Neoplasia: Factors Influencing the Treatment Response. 61
31370766 2019
12
Clinical Characteristics and Outcomes of Moraxella Keratitis. 61
30222715 2018
13
Indications, Clinical Outcomes, and Survival Rate of Pediatric Penetrating Keratoplasty in Suburban Malaysia: A 10-year Experience. 61
30800554 2018
14
Isolated severe microblepharon in a neonate: a rare case. 61
28803395 2018
15
Infective keratitis in Indian patients with corneal dystrophies. 61
29041837 2018
16
Boston keratoprosthesis type 1: outcomes of the first 38 cases performed at Moorfields Eye Hospital. 61
29440740 2018
17
Immune stromal keratitis: a rare ocular presentation of tuberculosis. 61
29622703 2018
18
Microbial characteristics of post-traumatic infective keratitis. 61
28708218 2018
19
Alcohol delamination of the corneal epithelium for recurrent corneal erosion syndrome. 61
30046528 2018
20
A Review of Corneal Collagen Cross-linking - Current Trends in Practice Applications. 61
30123383 2018
21
Tenon patch graft for corneal fistula: a rare entity treated by a simple technique. 61
29170188 2017
22
Bilateral simultaneous infective keratitis. 61
28359825 2017
23
Corneal Collagen Cross-linking for Treatment of Bacterial and Herpetic Keratitis. 61
28892949 2017
24
Current approaches to myopia control. 61
28212157 2017
25
Cylindrocarpon lichenicola keratomycosis in Nigeria: the challenge of limited access to effective antimicrobials. 61
28879155 2017
26
Epidemiological, clinical and laboratory findings of infectious keratitis at Mansoura Ophthalmic Center, Egypt. 61
28149778 2017
27
Urgent Therapeutic Grafting of Platelet-Rich Fibrin Membrane in Descemetocele. 61
27362878 2016
28
Direct microscopy in suppurative keratitis: a report from tertiary level hospital in Nepal. 61
28478466 2016
29
Indications and Visual Outcome of Penetrating Keratoplasty in Tertiary Eye Care Institute in Uttarakhand. 61
27504319 2016
30
Type 1 Boston keratoprosthesis: outcomes at two Canadian centres. 61
27085262 2016
31
Quantitative & qualitative analysis of endothelial cells of donor cornea before & after penetrating keratoplasty in different pathological conditions. 61
27121519 2016
32
Mechanical epithelial removal followed by corneal collagen crosslinking in progressive keratoconus: short-term complications. 61
26432132 2015
33
Severe microbial keratitis and associated perforation after corneal crosslinking for keratoconus. 61
25435381 2015
34
Corneal epithelial debridement for diagnosis and therapy of ocular surface disease. 61
25331183 2015
35
Outcome of therapeutic penetrating keratoplasty in a tertiary eye care center in Nepal. 61
26673279 2015
36
Epidemiology and etiological diagnosis of infective keratitis in eastern region of Nepal. 61
26695600 2015
37
Retrospective observational study of penetrating keratoplasty in the management of non-responsive microbial keratitis. 61
25935945 2014
38
Profile of sight-threatening infectious keratitis: a prospective study. 61
22863376 2013
39
Demographics and behaviour of patients with contact lens-related infectious keratitis in singapore. 61
24254236 2013
40
Indications for keratoplasty in Nepal: 2005 - 2010. 61
24172556 2013
41
Prevalence of ocular abnormalities in adults with Down syndrome in Hong Kong. 61
23376568 2013
42
Evaluation and management of corneal abrasions. 61
23317075 2013
43
Polymerase chain reaction-guided diagnosis of infective keratitis - a hospital-based study. 61
22746322 2012
44
Therapeutic penetrating keratoplasty in severe infective keratitis using glycerol-preserved donor corneas. 61
22854559 2012
45
Bacillus cereus infection after Descemet stripping endothelial keratoplasty. 61
22262217 2012
46
Epidemiological and microbiological profile of infective keratitis in Ahmedabad. 61
22824594 2012
47
Non-viral microbial keratitis: etiology, clinical features and visual outcome. 61
22414354 2012
48
Causative organisms in microbial keratitis, their sensitivity pattern and treatment outcome in western Nepal. 61
22344009 2012
49
New treatments for bacterial keratitis. 61
22991650 2012
50
Steroid associated infective keratitis - case studies for caution. 61
22059219 2011

Variations for Infective Keratitis

Expression for Infective Keratitis

Search GEO for disease gene expression data for Infective Keratitis.

Pathways for Infective Keratitis

GO Terms for Infective Keratitis

Sources for Infective Keratitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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