MCID: INF022
MIFTS: 24

Inflamed Seborrheic Keratosis

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Inflamed Seborrheic Keratosis

MalaCards integrated aliases for Inflamed Seborrheic Keratosis:

Name: Inflamed Seborrheic Keratosis 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:11685
ICD9CM 34 702.11
SNOMED-CT 67 442348004
ICD10 32 L82.0
UMLS 70 C0376117

Summaries for Inflamed Seborrheic Keratosis

MalaCards based summary : Inflamed Seborrheic Keratosis is related to keratosis, seborrheic and clear cell acanthoma. An important gene associated with Inflamed Seborrheic Keratosis is TCHH (Trichohyalin), and among its related pathways/superpathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Affiliated tissues include skin, myeloid and t cells.

Related Diseases for Inflamed Seborrheic Keratosis

Diseases related to Inflamed Seborrheic Keratosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 70)
# Related Disease Score Top Affiliating Genes
1 keratosis, seborrheic 29.1 TCHH CD1E CD1D CD1C CD1B CD1A
2 clear cell acanthoma 11.3
3 histiocytosis 10.2 CD1C CD1A
4 predominantly cortical thymoma 10.2 CD1E CD1A
5 tolosa-hunt syndrome 10.2 CD1E CD1A
6 dendritic cell thymoma 10.2 CD1E CD1A
7 multifocal motor neuropathy 10.1 CD1E CD1A
8 keratosis 10.1
9 inverted follicular keratosis 10.1
10 oral hairy leukoplakia 10.1 CD1E CD1A
11 pityriasis rosea 10.1 CD1E CD1A
12 kimura disease 10.1 CD1E CD1A
13 skin sarcoidosis 10.0 CD1C CD1B
14 mite infestation 10.0 CD1B CD1A
15 juvenile xanthogranuloma 10.0 CD1E CD1A
16 mixed type thymoma 10.0 CD1E CD1B CD1A
17 encapsulated thymoma 10.0 CD1E CD1B CD1A
18 sphenoid sinusitis 10.0 CD1E CD1B CD1A
19 epithelial malignant thymoma 10.0 CD1E CD1B CD1A
20 granulomatous orchitis 9.9 CD68 CD1E
21 multicentric reticulohistiocytosis 9.9 CD68 CD1E
22 epidermolytic acanthoma 9.9 TCHH CD68
23 dendritic cell tumor 9.8 CD68 CD1A
24 central nervous system sarcoma 9.8 CD1E CD1C CD1B CD1A
25 lichen nitidus 9.8 CD1E CD1C CD1B CD1A
26 phlyctenulosis 9.8 CD1E CD1C CD1B CD1A
27 interdigitating dendritic cell sarcoma 9.7 CD1E CD1C CD1B CD1A
28 seborrheic dermatitis 9.7 CD1E CD1C CD1B CD1A
29 diabetes insipidus, neurohypophyseal 9.7 CD1E CD1C CD1B CD1A
30 pharyngitis 9.7 PTGS2 CD1A
31 mycobacterium tuberculosis 1 9.7 CD1C CD1B CD1A CAMP
32 disease by infectious agent 9.7 CD1C CD1A CAMP
33 chronic laryngitis 9.7 CD1E CD1D CD1B CD1A
34 langerhans cell histiocytosis 9.7 CD68 CD1C CD1A
35 skin disease 9.6 TCHH CD1C CD1A CAMP
36 acanthoma 9.6 TCHH CD1E CD1C CD1B CD1A
37 necrobiosis lipoidica 9.5 CD68 CD1E CD1B CD1A
38 granulomatous dermatitis 9.5 CD68 CD1E CD1C CD1B
39 mycobacterium malmoense 9.4 CD1E CD1D CD1C CD1B CD1A
40 malignant histiocytic disease 9.4 CD1E CD1D CD1C CD1B CD1A
41 spongiotic dermatitis 9.4 CD1E CD1D CD1C CD1B CD1A
42 diencephalic astrocytoma 9.4 CD1E CD1D CD1C CD1B CD1A
43 orbital cancer 9.4 CD1E CD1D CD1C CD1B CD1A
44 marginal corneal ulcer 9.4 CD1E CD1D CD1C CD1B CD1A
45 central epithelioid sarcoma 9.4 CD1E CD1D CD1C CD1B CD1A
46 vulvar proximal-type epithelioid sarcoma 9.4 CD1E CD1D CD1C CD1B CD1A
47 polyclonal hypergammaglobulinemia 9.4 CD1E CD1D CD1C CD1B CD1A
48 diencephalic neoplasm 9.4 CD1E CD1D CD1C CD1B CD1A
49 erdheim-chester disease 9.4 CD1E CD1D CD1C CD1B CD1A
50 psoriasis 15 9.4 CD1E CD1D CD1C CD1B CD1A

Graphical network of the top 20 diseases related to Inflamed Seborrheic Keratosis:



Diseases related to Inflamed Seborrheic Keratosis

Symptoms & Phenotypes for Inflamed Seborrheic Keratosis

Drugs & Therapeutics for Inflamed Seborrheic Keratosis

Search Clinical Trials , NIH Clinical Center for Inflamed Seborrheic Keratosis

Genetic Tests for Inflamed Seborrheic Keratosis

Anatomical Context for Inflamed Seborrheic Keratosis

MalaCards organs/tissues related to Inflamed Seborrheic Keratosis:

40
Skin, Myeloid, T Cells

Publications for Inflamed Seborrheic Keratosis

Articles related to Inflamed Seborrheic Keratosis:

# Title Authors PMID Year
1
Epithelial sheath neuroma: A case report and literature review. 61
32383640 2020
2
Hypergranulotic dyscornification: 30 cases of a striking epithelial reaction pattern. 61
31157457 2019
3
Verrucous melanoma masquerading as a seborrheic keratosis. 61
30865414 2019
4
Dermatologic toxicity from novel therapy using antimicrobial peptide LL-37 in melanoma: A detailed examination of the clinicopathologic features. 61
29665030 2018
5
Overexpression of linker for activated T cells, cyclooxygenase-2, CD1a, CD68 and myeloid/histiocyte antigen in an inflamed seborrheic keratosis. 61
22540084 2011
6
Epidermal panfolliculoma: A report of 2 cases. 61
21294291 2011
7
The significance of reflectance confocal microscopy in the assessment of solitary pink skin lesions. 61
19398144 2009
8
Herpesvirus infection of seborrheic keratoses. 61
11285412 2001

Variations for Inflamed Seborrheic Keratosis

Expression for Inflamed Seborrheic Keratosis

Search GEO for disease gene expression data for Inflamed Seborrheic Keratosis.

Pathways for Inflamed Seborrheic Keratosis

GO Terms for Inflamed Seborrheic Keratosis

Cellular components related to Inflamed Seborrheic Keratosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.8 CD1E CD1D CD1C CD1B CD1A CAMP
2 lysosome GO:0005764 9.65 CD68 CD1E CD1D CD1C CD1B
3 external side of plasma membrane GO:0009897 9.55 CD1E CD1D CD1C CD1B CD1A
4 lysosomal membrane GO:0005765 9.54 CD68 CD1D CD1B
5 endosome GO:0005768 9.43 CD68 CD1E CD1D CD1C CD1B CD1A
6 endosome membrane GO:0010008 9.02 CD68 CD1D CD1C CD1B CD1A

Biological processes related to Inflamed Seborrheic Keratosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.8 LAT CD1E CD1D CD1C CD1B CD1A
2 adaptive immune response GO:0002250 9.77 LAT CD1E CD1C CD1B CD1A
3 immune response GO:0006955 9.73 LAT CD1E CD1D CD1C CD1B CD1A
4 regulation of immune response GO:0050776 9.71 CD1D CD1C CD1B CD1A
5 positive regulation of T cell mediated cytotoxicity GO:0001916 9.55 CD1E CD1D CD1C CD1B CD1A
6 antigen processing and presentation, exogenous lipid antigen via MHC class Ib GO:0048007 9.35 CD1E CD1D CD1C CD1B CD1A
7 antigen processing and presentation, endogenous lipid antigen via MHC class Ib GO:0048006 9.02 CD1E CD1D CD1C CD1B CD1A

Molecular functions related to Inflamed Seborrheic Keratosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipopeptide binding GO:0071723 9.55 CD1E CD1D CD1C CD1B CD1A
2 exogenous lipid antigen binding GO:0030884 9.35 CD1E CD1D CD1C CD1B CD1A
3 endogenous lipid antigen binding GO:0030883 9.02 CD1E CD1D CD1C CD1B CD1A

Sources for Inflamed Seborrheic Keratosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....