MCID: INF036
MIFTS: 23

Inflammatory and Toxic Neuropathy

Categories: Neuronal diseases

Aliases & Classifications for Inflammatory and Toxic Neuropathy

MalaCards integrated aliases for Inflammatory and Toxic Neuropathy:

Name: Inflammatory and Toxic Neuropathy 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:2537
ICD9CM 34 357
SNOMED-CT 67 193172009
UMLS 70 C0154758

Summaries for Inflammatory and Toxic Neuropathy

MalaCards based summary : Inflammatory and Toxic Neuropathy is related to type 1 diabetes mellitus 23 and necrobiosis lipoidica. An important gene associated with Inflammatory and Toxic Neuropathy is INS (Insulin), and among its related pathways/superpathways are Insulin resistance and AGE-RAGE signaling pathway in diabetic complications. Affiliated tissues include liver, lung and bone, and related phenotype is liver/biliary system.

Related Diseases for Inflammatory and Toxic Neuropathy

Diseases related to Inflammatory and Toxic Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 353)
# Related Disease Score Top Affiliating Genes
1 type 1 diabetes mellitus 23 10.3 TNF INS
2 necrobiosis lipoidica 10.3 TNF INS
3 neurotic disorder 10.3 TNF INS
4 severe nonproliferative diabetic retinopathy 10.3 INS ALB
5 marasmus 10.3 INS ALB
6 kidney hypertrophy 10.3 INS ALB
7 polyneuropathy due to drug 10.3 RPRD1B MIDN
8 jejunoileitis 10.2 TNF ALB
9 peptic esophagitis 10.2 TNF ALB
10 pasteurellosis 10.2 TNF ALB
11 malignant otitis externa 10.2 INS CRP
12 otitis externa 10.2 INS CRP
13 uvulitis 10.2 INS CRP
14 miller fisher syndrome 10.2 TNF ALB
15 cavernous sinus thrombosis 10.2 INS CRP
16 silent myocardial infarction 10.2 INS CRP
17 neurogenic arthropathy 10.2 INS CRP
18 external ear disease 10.2 INS CRP
19 balanitis 10.2 INS CRP
20 acute insulin response 10.2 INS CRP
21 drug reaction with eosinophilia and systemic symptoms 10.2 TNF CRP
22 functional gastric disease 10.2 INS ALB
23 anterior scleritis 10.1 TNF CRP
24 rheumatoid arthritis interstitial lung disease 10.1 TNF CRP
25 posterior scleritis 10.1 TNF CRP
26 macular retinal edema 10.1 TNF INS ALB
27 esophageal varix 10.1 INS ALB
28 skeletal tuberculosis 10.1 TNF CRP
29 tuberculous epididymitis 10.1 TNF CRP
30 taeniasis 10.1 TNF ALB
31 louse-borne relapsing fever 10.1 TNF CRP
32 opportunistic bacterial infectious disease 10.1 TNF CRP
33 hypotrichosis 2 10.1 TNF INS ALB
34 tertiary syphilis 10.1 TNF CRP
35 nocardiosis 10.1 TNF CRP
36 arachnoiditis 10.1 TNF CRP
37 lens disease 10.1 TNF INS ALB
38 chronic duodenal ileus 10.1 CRP ALB
39 hypotrichosis 1 10.1 TNF INS ALB
40 hair disease 10.1 TNF INS ALB
41 retinal vascular disease 10.1 TNF INS ALB
42 soft tissue sarcoma 10.1 TNF CRP
43 oral tuberculosis 10.1 TNF CRP
44 cerebritis 10.1 TNF CRP
45 portal hypertension 10.1 TNF INS ALB
46 tracheitis 10.1 TNF CRP
47 viral exanthem 10.1 TNF CRP
48 mononeuritis of upper limb and mononeuritis multiplex 10.1 TNF CRP
49 mononeuritis multiplex 10.1 TNF CRP
50 lymph node tuberculosis 10.1 TNF CRP

Graphical network of the top 20 diseases related to Inflammatory and Toxic Neuropathy:



Diseases related to Inflammatory and Toxic Neuropathy

Symptoms & Phenotypes for Inflammatory and Toxic Neuropathy

MGI Mouse Phenotypes related to Inflammatory and Toxic Neuropathy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 liver/biliary system MP:0005370 9.1 ALB ALDH2 INS SELE TNF UROS

Drugs & Therapeutics for Inflammatory and Toxic Neuropathy

Search Clinical Trials , NIH Clinical Center for Inflammatory and Toxic Neuropathy

Genetic Tests for Inflammatory and Toxic Neuropathy

Anatomical Context for Inflammatory and Toxic Neuropathy

MalaCards organs/tissues related to Inflammatory and Toxic Neuropathy:

40
Liver, Lung, Bone, Heart, Kidney, Lymph Node, Skin

Publications for Inflammatory and Toxic Neuropathy

Articles related to Inflammatory and Toxic Neuropathy:

# Title Authors PMID Year
1
The accuracy of discharge diagnosis coding for Amyotrophic Lateral Sclerosis in a large teaching hospital. 61
19657715 2009

Variations for Inflammatory and Toxic Neuropathy

Expression for Inflammatory and Toxic Neuropathy

Search GEO for disease gene expression data for Inflammatory and Toxic Neuropathy.

Pathways for Inflammatory and Toxic Neuropathy

Pathways related to Inflammatory and Toxic Neuropathy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.47 TNF PRKCE INS
2 11.33 TNF SELE PRKCE
3
Show member pathways
11.26 TNF INS CRP ALB
4
Show member pathways
11.11 TNF PRKCE INS
5 10.6 TNF CRP

GO Terms for Inflammatory and Toxic Neuropathy

Biological processes related to Inflammatory and Toxic Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 leukocyte tethering or rolling GO:0050901 9.26 TNF SELE
2 negative regulation of lipid catabolic process GO:0050995 9.16 TNF INS
3 regulation of protein secretion GO:0050708 8.96 TNF INS
4 negative regulation of lipid storage GO:0010888 8.62 TNF CRP

Sources for Inflammatory and Toxic Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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