IBD11
MCID: INF072
MIFTS: 24

Inflammatory Bowel Disease 11 (IBD11)

Categories: Blood diseases, Bone diseases, Gastrointestinal diseases, Genetic diseases, Immune diseases, Rare diseases

Aliases & Classifications for Inflammatory Bowel Disease 11

MalaCards integrated aliases for Inflammatory Bowel Disease 11:

Name: Inflammatory Bowel Disease 11 56 12 13 15 71
Ibd11 56 12

Characteristics:

OMIM:

56
Inheritance:
multifactorial

Miscellaneous:
5-10% of patients have a first degree relative with ibd (ulcerative colitis or crohn disease)


HPO:

31
inflammatory bowel disease 11:
Inheritance multifactorial inheritance


Classifications:



External Ids:

Disease Ontology 12 DOID:0110894
OMIM 56 191390
OMIM Phenotypic Series 56 PS266600
MedGen 41 C2674051
UMLS 71 C2674051

Summaries for Inflammatory Bowel Disease 11

Disease Ontology : 12 An inflammatory bowel disease that has material basis in variation in the chromosome region 7q22.

MalaCards based summary : Inflammatory Bowel Disease 11, also known as ibd11, is related to inflammatory bowel disease, and has symptoms including abdominal pain and diarrhea. An important gene associated with Inflammatory Bowel Disease 11 is IBD11 (Inflammatory Bowel Disease 11). The drugs Prednisone and Anti-Inflammatory Agents have been mentioned in the context of this disorder. Affiliated tissues include colon and bone, and related phenotypes are abdominal pain and weight loss

More information from OMIM: 191390 PS266600

Related Diseases for Inflammatory Bowel Disease 11

Symptoms & Phenotypes for Inflammatory Bowel Disease 11

Human phenotypes related to Inflammatory Bowel Disease 11:

31
# Description HPO Frequency HPO Source Accession
1 abdominal pain 31 HP:0002027
2 weight loss 31 HP:0001824
3 inflammation of the large intestine 31 HP:0002037
4 hematochezia 31 HP:0002573

Symptoms via clinical synopsis from OMIM:

56
Abdomen Gastrointestinal:
abdominal pain
diarrhea
bloody diarrhea
mucosal and submucosal inflammation limited to colon, always involving rectum

Growth Weight:
weight loss

Clinical features from OMIM:

191390

UMLS symptoms related to Inflammatory Bowel Disease 11:


abdominal pain, diarrhea

Drugs & Therapeutics for Inflammatory Bowel Disease 11

Drugs for Inflammatory Bowel Disease 11 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
2 Anti-Inflammatory Agents Phase 4
3 Hormone Antagonists Phase 4
4 glucocorticoids Phase 4
5 Antineoplastic Agents, Hormonal Phase 4
6 Hormones Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Steroid-induced Mood Changes in Patients With Inflammatory Bowel Disease Completed NCT01981889 Phase 4 Prednisone

Search NIH Clinical Center for Inflammatory Bowel Disease 11

Genetic Tests for Inflammatory Bowel Disease 11

Anatomical Context for Inflammatory Bowel Disease 11

MalaCards organs/tissues related to Inflammatory Bowel Disease 11:

40
Colon, Bone

Publications for Inflammatory Bowel Disease 11

Articles related to Inflammatory Bowel Disease 11:

(show all 12)
# Title Authors PMID Year
1
Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL). 56
20228798 2010
2
Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease. 56
11289722 2001
3
Association of ulcerative colitis with rare VNTR alleles of the human intestinal mucin gene, MUC3. 56
9931338 1999
4
Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. 56
8841195 1996
5
Crohn's disease in patients treated with etanercept. 61
31793319 2020
6
Characteristics and outcomes of acute colitis diagnosed on cross-sectional imaging presenting via the emergency department in an Irish academic medical centre. 61
31925651 2020
7
Long-term results after endoanal advancement flap repair for fistulas-in-ano. How important is the aetiology? 61
25652877 2015
8
Clinical features of pyoderma gangrenosum and current diagnostic trends. 61
21292348 2011
9
Fluoroscopic and CT enteroclysis in children: initial experience, technical feasibility, and utility. 61
18256816 2008
10
[Current status of clinical nutrition at the network of public hospitals from Castilla y León]. 61
16771118 2006
11
Incidence and causes of rectal bleeding in general practice as detected by colonoscopy. 61
8731622 1996
12
Incidence of methanogenic bacteria in a sigmoidoscopy population: an association of methanogenic bacteria and diverticulosis. 61
3721294 1986

Variations for Inflammatory Bowel Disease 11

Expression for Inflammatory Bowel Disease 11

Search GEO for disease gene expression data for Inflammatory Bowel Disease 11.

Pathways for Inflammatory Bowel Disease 11

GO Terms for Inflammatory Bowel Disease 11

Sources for Inflammatory Bowel Disease 11

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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