IBD11
MCID: INF072
MIFTS: 22

Inflammatory Bowel Disease 11 (IBD11)

Categories: Blood diseases, Bone diseases, Gastrointestinal diseases, Genetic diseases, Immune diseases, Rare diseases

Aliases & Classifications for Inflammatory Bowel Disease 11

MalaCards integrated aliases for Inflammatory Bowel Disease 11:

Name: Inflammatory Bowel Disease 11 57 12 13 72
Ibd11 57 12

Characteristics:

OMIM:

57
Inheritance:
multifactorial

Miscellaneous:
5-10% of patients have a first degree relative with ibd (ulcerative colitis or crohn disease)


HPO:

32
inflammatory bowel disease 11:
Inheritance multifactorial inheritance


Classifications:



External Ids:

Disease Ontology 12 DOID:0110894
MedGen 42 C2674051
UMLS 72 C2674051

Summaries for Inflammatory Bowel Disease 11

Disease Ontology : 12 An inflammatory bowel disease that has material basis in variation in the chromosome region 7q22.

MalaCards based summary : Inflammatory Bowel Disease 11, also known as ibd11, is related to inflammatory bowel disease, and has symptoms including abdominal pain and diarrhea. An important gene associated with Inflammatory Bowel Disease 11 is IBD11 (Inflammatory Bowel Disease 11). The drugs Prednisone and Anti-Inflammatory Agents have been mentioned in the context of this disorder. Affiliated tissues include colon, and related phenotypes are abdominal pain and weight loss

More information from OMIM: 191390 PS266600

Related Diseases for Inflammatory Bowel Disease 11

Symptoms & Phenotypes for Inflammatory Bowel Disease 11

Human phenotypes related to Inflammatory Bowel Disease 11:

32
# Description HPO Frequency HPO Source Accession
1 abdominal pain 32 HP:0002027
2 weight loss 32 HP:0001824
3 inflammation of the large intestine 32 HP:0002037
4 hematochezia 32 HP:0002573

Symptoms via clinical synopsis from OMIM:

57
Abdomen Gastrointestinal:
abdominal pain
diarrhea
bloody diarrhea
mucosal and submucosal inflammation limited to colon, always involving rectum

Growth Weight:
weight loss

Clinical features from OMIM:

191390

UMLS symptoms related to Inflammatory Bowel Disease 11:


abdominal pain, diarrhea

Drugs & Therapeutics for Inflammatory Bowel Disease 11

Drugs for Inflammatory Bowel Disease 11 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
2 Anti-Inflammatory Agents Phase 4
3 glucocorticoids Phase 4
4 Hormones Phase 4
5 Antineoplastic Agents, Hormonal Phase 4
6 Hormone Antagonists Phase 4
7 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Steroid-induced Mood Changes in Patients With Inflammatory Bowel Disease Completed NCT01981889 Phase 4 Prednisone

Search NIH Clinical Center for Inflammatory Bowel Disease 11

Genetic Tests for Inflammatory Bowel Disease 11

Anatomical Context for Inflammatory Bowel Disease 11

MalaCards organs/tissues related to Inflammatory Bowel Disease 11:

41
Colon

Publications for Inflammatory Bowel Disease 11

Articles related to Inflammatory Bowel Disease 11:

# Title Authors PMID Year
1
Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL). 8
20228798 2010
2
Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease. 8
11289722 2001
3
Association of ulcerative colitis with rare VNTR alleles of the human intestinal mucin gene, MUC3. 8
9931338 1999
4
Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. 8
8841195 1996
5
Long-term results after endoanal advancement flap repair for fistulas-in-ano. How important is the aetiology? 38
25652877 2015
6
Clinical features of pyoderma gangrenosum and current diagnostic trends. 38
21292348 2011
7
Fluoroscopic and CT enteroclysis in children: initial experience, technical feasibility, and utility. 38
18256816 2008
8
[Current status of clinical nutrition at the network of public hospitals from Castilla y León]. 38
16771118 2006
9
Incidence and causes of rectal bleeding in general practice as detected by colonoscopy. 38
8731622 1996
10
Incidence of methanogenic bacteria in a sigmoidoscopy population: an association of methanogenic bacteria and diverticulosis. 38
3721294 1986

Variations for Inflammatory Bowel Disease 11

Expression for Inflammatory Bowel Disease 11

Search GEO for disease gene expression data for Inflammatory Bowel Disease 11.

Pathways for Inflammatory Bowel Disease 11

GO Terms for Inflammatory Bowel Disease 11

Sources for Inflammatory Bowel Disease 11

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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