Inflammatory Bowel Disease 16 disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Inflammatory Bowel Disease 16

MalaCards integrated aliases for Inflammatory Bowel Disease 16:

Name: Inflammatory Bowel Disease 16 ⁵⁸ ¹² ¹⁵ ⁷⁴

Ibd16 ⁵⁸ ¹²

Inflammatory Bowel Disease 16, Susceptibility to ¹³

Classifications:

MalaCards categories:
Global: Genetic diseases Rare diseases
Anatomical: Gastrointestinal diseases Bone diseases Immune diseases Blood diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0110896

OMIM ⁵⁸ 612259

UMLS ⁷⁴ C2677093

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Summaries for Inflammatory Bowel Disease 16

Disease Ontology : ¹² An inflammatory bowel disease that has material basis in variation in the chromosome region 9q32.

MalaCards based summary : Inflammatory Bowel Disease 16, also known as ibd16, is related to inflammatory bowel disease and t-cell adult acute lymphocytic leukemia. An important gene associated with Inflammatory Bowel Disease 16 is IBD16 (Inflammatory Bowel Disease-16), and among its related pathways/superpathways are Cell surface interactions at the vascular wall and Cell adhesion molecules (CAMs). Related phenotypes are Decreased viability in esophageal squamous lineage and Reduced mammosphere formation

Description from OMIM: 612259

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Related Diseases for Inflammatory Bowel Disease 16

Diseases in the Inflammatory Bowel Disease family:

Inflammatory Bowel Disease 11	Inflammatory Bowel Disease 1
Inflammatory Bowel Disease 2	Inflammatory Bowel Disease 3
Inflammatory Bowel Disease 7	Inflammatory Bowel Disease 5
Inflammatory Bowel Disease 8	Inflammatory Bowel Disease 6
Inflammatory Bowel Disease 4	Inflammatory Bowel Disease 9
Inflammatory Bowel Disease 10	Inflammatory Bowel Disease 12
Inflammatory Bowel Disease 13	Inflammatory Bowel Disease 14
Inflammatory Bowel Disease 15	Inflammatory Bowel Disease 16
Inflammatory Bowel Disease 17	Inflammatory Bowel Disease 18
Inflammatory Bowel Disease 19	Inflammatory Bowel Disease 20
Inflammatory Bowel Disease 21	Inflammatory Bowel Disease 22
Inflammatory Bowel Disease 23	Inflammatory Bowel Disease 24
Inflammatory Bowel Disease 25, Autosomal Recessive	Inflammatory Bowel Disease 26
Inflammatory Bowel Disease 27	Inflammatory Bowel Disease 28, Autosomal Recessive
Inflammatory Bowel Disease 29	Inflammatory Bowel Disease 28
Inflammatory Bowel Disease 25

Diseases related to Inflammatory Bowel Disease 16 via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score	Top Affiliating Genes
1	inflammatory bowel disease	9.9
2	t-cell adult acute lymphocytic leukemia	9.9	CD2 CD7
3	chronic nk-cell lymphocytosis	9.9	CD2 CD7
4	thymic dysplasia	9.9	CD2 CD7
5	follicular mucinosis	9.8	CD2 CD7
6	sezary's disease	9.8	CD2 CD7
7	hematologic cancer	9.7	CD2 CD7
8	lymphoma, non-hodgkin, familial	9.5	CD44 CD7

Graphical network of the top 20 diseases related to Inflammatory Bowel Disease 16:

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Symptoms & Phenotypes for Inflammatory Bowel Disease 16

Clinical features from OMIM:

612259

GenomeRNAi Phenotypes related to Inflammatory Bowel Disease 16 according to GeneCards Suite gene sharing:

²⁷

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Decreased viability in esophageal squamous lineage	GR00235-A	9.26	CD2 CD44 CD6 CD7
2	Reduced mammosphere formation	GR00396-S	8.8	CD44 CD6 CD7

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Drugs & Therapeutics for Inflammatory Bowel Disease 16

Search Clinical Trials , NIH Clinical Center for Inflammatory Bowel Disease 16

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Genetic Tests for Inflammatory Bowel Disease 16

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Anatomical Context for Inflammatory Bowel Disease 16

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Publications for Inflammatory Bowel Disease 16

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Genes for Inflammatory Bowel Disease 16

Genes related to Inflammatory Bowel Disease 16 (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	IBD16	Inflammatory Bowel Disease-16	Genetic Locus	58.59	Susceptibility factor ⁵⁸ GeneCards inferred via : Gene name (show sections)
2	CD6	CD6 Molecule	Protein Coding	15.06	DISEASES inferred ¹⁵
3	CD2	CD2 Molecule	Protein Coding	14.76	DISEASES inferred ¹⁵
4	CD44	CD44 Molecule (Indian Blood Group)	Protein Coding	14	DISEASES inferred ¹⁵
5	CD7	CD7 Molecule	Protein Coding	4.92	DISEASES inferred ¹⁵

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Variations for Inflammatory Bowel Disease 16

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Expression for Inflammatory Bowel Disease 16

Search GEO for disease gene expression data for Inflammatory Bowel Disease 16.

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Pathways for Inflammatory Bowel Disease 16

Pathways related to Inflammatory Bowel Disease 16 according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Cell surface interactions at the vascular wall ⁶⁷ Show member pathways Fibronectin matrix formation ⁶⁷ PECAM1 interactions ⁶⁷ Tie2 Signaling ⁶⁷	11.57	CD2 CD44
2	Cell adhesion molecules (CAMs) ³⁸	11.42	CD2 CD6
3	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁶	11.22	CD2 CD44
4	Innate Lymphoid Cell Differentiation Pathways ⁶⁶	10.86	CD44 CD7
5	Hematopoietic cell lineage ³⁸	10.79	CD2 CD44 CD7

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GO Terms for Inflammatory Bowel Disease 16

Biological processes related to Inflammatory Bowel Disease 16 according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	leukocyte migration	GO:0050900	9.26	CD2 CD44
2	cell-cell adhesion	GO:0098609	9.16	CD2 CD44
3	cell adhesion	GO:0007155	9.13	CD2 CD44 CD6
4	T cell activation	GO:0042110	8.62	CD2 CD7

Molecular functions related to Inflammatory Bowel Disease 16 according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	signaling receptor activity	GO:0038023	8.62	CD2 CD7

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Sources for Inflammatory Bowel Disease 16

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia

Inflammatory Bowel Disease 16 (IBD16)

Aliases & Classifications for Inflammatory Bowel Disease 16

MalaCards integrated aliases for Inflammatory Bowel Disease 16:

Classifications:

External Ids:

Summaries for Inflammatory Bowel Disease 16

Related Diseases for Inflammatory Bowel Disease 16

Diseases in the Inflammatory Bowel Disease family:

Diseases related to Inflammatory Bowel Disease 16 via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Inflammatory Bowel Disease 16:

Symptoms & Phenotypes for Inflammatory Bowel Disease 16

Clinical features from OMIM:

GenomeRNAi Phenotypes related to Inflammatory Bowel Disease 16 according to GeneCards Suite gene sharing:

Drugs & Therapeutics for Inflammatory Bowel Disease 16

Genetic Tests for Inflammatory Bowel Disease 16

Anatomical Context for Inflammatory Bowel Disease 16

Publications for Inflammatory Bowel Disease 16

Genes for Inflammatory Bowel Disease 16

Genes related to Inflammatory Bowel Disease 16 (1 elite genes):

Variations for Inflammatory Bowel Disease 16

Expression for Inflammatory Bowel Disease 16

Pathways for Inflammatory Bowel Disease 16

Pathways related to Inflammatory Bowel Disease 16 according to GeneCards Suite gene sharing:

GO Terms for Inflammatory Bowel Disease 16

Biological processes related to Inflammatory Bowel Disease 16 according to GeneCards Suite gene sharing:

Molecular functions related to Inflammatory Bowel Disease 16 according to GeneCards Suite gene sharing:

Sources for Inflammatory Bowel Disease 16