IBD25
MCID: INF162
MIFTS: 23

Inflammatory Bowel Disease 25 (IBD25)

Categories: Blood diseases, Bone diseases, Gastrointestinal diseases, Genetic diseases, Immune diseases, Rare diseases

Aliases & Classifications for Inflammatory Bowel Disease 25

MalaCards integrated aliases for Inflammatory Bowel Disease 25:

Name: Inflammatory Bowel Disease 25 12 15
Early Onset Autosomal Recessive Inflammatory Bowel Disease 25 12
Inflammatory Bowel Disease 25, Autosomal Recessive 70
Ibd25 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0110909
UMLS 70 C2675508

Summaries for Inflammatory Bowel Disease 25

Disease Ontology : 12 An inflammatory bowel disease characterized by autosomal recessive inheritance that has material basis in homozygous mutation in the IL10RB gene on chromosome 21q22.

MalaCards based summary : Inflammatory Bowel Disease 25, also known as early onset autosomal recessive inflammatory bowel disease 25, is related to inflammatory bowel disease 25, autosomal recessive and peptic esophagitis. An important gene associated with Inflammatory Bowel Disease 25 is IL10RB (Interleukin 10 Receptor Subunit Beta), and among its related pathways/superpathways are Human cytomegalovirus infection and Spinal Cord Injury. Affiliated tissues include bone.

Related Diseases for Inflammatory Bowel Disease 25

Diseases in the Inflammatory Bowel Disease family:

Inflammatory Bowel Disease 11 Inflammatory Bowel Disease 1
Inflammatory Bowel Disease 2 Inflammatory Bowel Disease 3
Inflammatory Bowel Disease 7 Inflammatory Bowel Disease 5
Inflammatory Bowel Disease 8 Inflammatory Bowel Disease 6
Inflammatory Bowel Disease 4 Inflammatory Bowel Disease 9
Inflammatory Bowel Disease 10 Inflammatory Bowel Disease 12
Inflammatory Bowel Disease 13 Inflammatory Bowel Disease 14
Inflammatory Bowel Disease 15 Inflammatory Bowel Disease 16
Inflammatory Bowel Disease 17 Inflammatory Bowel Disease 18
Inflammatory Bowel Disease 19 Inflammatory Bowel Disease 20
Inflammatory Bowel Disease 21 Inflammatory Bowel Disease 22
Inflammatory Bowel Disease 23 Inflammatory Bowel Disease 24
Inflammatory Bowel Disease 25, Autosomal Recessive Inflammatory Bowel Disease 26
Inflammatory Bowel Disease 27 Inflammatory Bowel Disease 28, Autosomal Recessive
Inflammatory Bowel Disease 29 Inflammatory Bowel Disease 30
Inflammatory Bowel Disease 28 Inflammatory Bowel Disease 25
Alpi-Related Inflammatory Bowel Disease Trim22-Related Inflammatory Bowel Disease
Rare Inflammatory Bowel Disease

Diseases related to Inflammatory Bowel Disease 25 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 29)
# Related Disease Score Top Affiliating Genes
1 inflammatory bowel disease 25, autosomal recessive 32.9 IL10RB IBD25
2 peptic esophagitis 9.8 TNF PTGS2
3 esophagitis 9.8 TNF PTGS2
4 bursitis 9.8 TNF PTGS2
5 endometrial disease 9.8 TNF PTGS2
6 cerebral artery occlusion 9.8 TNF PTGS2
7 erythema multiforme 9.8 TNF PTGS2
8 pharyngitis 9.8 TNF PTGS2
9 spotted fever 9.8 TNF PTGS2
10 oral submucous fibrosis 9.8 TNF PTGS2
11 viral encephalitis 9.8 TNF PTGS2
12 mumps 9.8 TNF IL10RB
13 pain agnosia 9.8 TNF PTGS2
14 agnosia 9.8 TNF PTGS2
15 colonic benign neoplasm 9.8 TNF PTGS2
16 gastric ulcer 9.8 TNF PTGS2
17 prostatitis 9.8 TNF PTGS2
18 peptic ulcer disease 9.8 TNF PTGS2
19 proteasome-associated autoinflammatory syndrome 1 9.8 TNF PTGS2
20 toxic encephalopathy 9.8 TNF PTGS2
21 atrophic gastritis 9.7 TNF PTGS2
22 gastritis 9.7 TNF PTGS2
23 cystitis 9.7 TNF PTGS2
24 periodontitis 9.7 TNF PTGS2
25 arthropathy 9.7 TNF PTGS2
26 bone inflammation disease 9.6 TNF PTGS2
27 colitis 9.6 TNF PTGS2 IL10RB
28 urticaria 9.6 TNF PTGS2
29 neuritis 9.5 TNF PTGS2

Graphical network of the top 20 diseases related to Inflammatory Bowel Disease 25:



Diseases related to Inflammatory Bowel Disease 25

Symptoms & Phenotypes for Inflammatory Bowel Disease 25

Drugs & Therapeutics for Inflammatory Bowel Disease 25

Search Clinical Trials , NIH Clinical Center for Inflammatory Bowel Disease 25

Genetic Tests for Inflammatory Bowel Disease 25

Anatomical Context for Inflammatory Bowel Disease 25

MalaCards organs/tissues related to Inflammatory Bowel Disease 25:

40
Bone

Publications for Inflammatory Bowel Disease 25

Articles related to Inflammatory Bowel Disease 25:

# Title Authors PMID Year
1
Pediatric Inflammatory Bowel Disease. 61
27889728 2016
2
Epidermolysis bullosa acquisita: a retrospective analysis of 12 patients evaluated in four tertiary hospitals in Spain. 61
24890437 2014

Variations for Inflammatory Bowel Disease 25

Expression for Inflammatory Bowel Disease 25

Search GEO for disease gene expression data for Inflammatory Bowel Disease 25.

Pathways for Inflammatory Bowel Disease 25

GO Terms for Inflammatory Bowel Disease 25

Biological processes related to Inflammatory Bowel Disease 25 according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.54 TNF PTGS2 IL10RB
2 regulation of inflammatory response GO:0050727 9.51 TNF PTGS2
3 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.49 TNF PTGS2
4 response to organic substance GO:0010033 9.48 TNF PTGS2
5 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 9.46 TNF PTGS2
6 response to glucocorticoid GO:0051384 9.43 TNF PTGS2
7 positive regulation of smooth muscle cell proliferation GO:0048661 9.4 TNF PTGS2
8 cytokine-mediated signaling pathway GO:0019221 9.33 TNF PTGS2 IL10RB
9 positive regulation of nitric oxide biosynthetic process GO:0045429 9.32 TNF PTGS2
10 positive regulation of JAK-STAT cascade GO:0046427 9.26 TNF IL10RB
11 positive regulation of heterotypic cell-cell adhesion GO:0034116 8.96 TNF CEACAM6
12 positive regulation of fever generation GO:0031622 8.62 TNF PTGS2

Sources for Inflammatory Bowel Disease 25

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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