IBD9
MCID: INF092
MIFTS: 30

Inflammatory Bowel Disease 9 (IBD9)

Categories: Blood diseases, Bone diseases, Gastrointestinal diseases, Genetic diseases, Immune diseases, Rare diseases

Aliases & Classifications for Inflammatory Bowel Disease 9

MalaCards integrated aliases for Inflammatory Bowel Disease 9:

Name: Inflammatory Bowel Disease 9 56 12 13 15 71
Ibd9 56 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0110886
OMIM 56 608448
OMIM Phenotypic Series 56 PS266600
UMLS 71 C1838019

Summaries for Inflammatory Bowel Disease 9

Disease Ontology : 12 An inflammatory bowel disease that has material basis in variation in the chromosome region 3p26.

MalaCards based summary : Inflammatory Bowel Disease 9, also known as ibd9, is related to inflammatory bowel disease and inflammatory bowel disease 3. An important gene associated with Inflammatory Bowel Disease 9 is IBD9 (Inflammatory Bowel Disease 9), and among its related pathways/superpathways are Development Endothelin-1/EDNRA signaling and Immune response Fc epsilon RI pathway. The drugs Antibodies and Immunoglobulins have been mentioned in the context of this disorder. Affiliated tissues include liver and bone.

More information from OMIM: 608448 PS266600

Related Diseases for Inflammatory Bowel Disease 9

Graphical network of the top 20 diseases related to Inflammatory Bowel Disease 9:



Diseases related to Inflammatory Bowel Disease 9

Symptoms & Phenotypes for Inflammatory Bowel Disease 9

Clinical features from OMIM:

608448

Drugs & Therapeutics for Inflammatory Bowel Disease 9

Drugs for Inflammatory Bowel Disease 9 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antibodies
2 Immunoglobulins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Quantification of GADD34 Expression in Rheumatoid Arthritis Completed NCT02401165

Search NIH Clinical Center for Inflammatory Bowel Disease 9

Genetic Tests for Inflammatory Bowel Disease 9

Anatomical Context for Inflammatory Bowel Disease 9

MalaCards organs/tissues related to Inflammatory Bowel Disease 9:

40
Liver, Bone

Publications for Inflammatory Bowel Disease 9

Articles related to Inflammatory Bowel Disease 9:

(show all 18)
# Title Authors PMID Year
1
Evidence for an inflammatory bowel disease locus on chromosome 3p26: linkage, transmission/disequilibrium and partitioning of linkage. 56
12354785 2002
2
Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease. 56
11156639 2001
3
Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. 56
8841195 1996
4
[A multicenter study of the condition of children's rheumatic disease associated medical resources in Fujian province]. 61
31795556 2019
5
Lymphomatoid Papulosis Type B in a Patient with Crohn's Disease Treated with TNF-Alpha Inhibitors Infliximab and Adalimumab. 61
31542070 2019
6
The diagnostic performance of (99m)Tc-HMPAO radiolabeled leucocytes scintigraphy in the investigations of infection. A single center experience. 61
26665208 2015
7
Predicting inadequate bowel preparation for colonoscopy in participants receiving split-dose bowel preparation: development and validation of a prediction score. 61
25600879 2015
8
Reduction of CD68+ macrophages and decreased IL-17 expression in intestinal mucosa of patients with inflammatory bowel disease strongly correlate with endoscopic response and mucosal healing following infliximab therapy. 61
23448791 2013
9
Infliximab safety profile and long-term applicability in inflammatory bowel disease: 9-year experience in clinical practice. 61
20002026 2010
10
Evaluation of the MLH1 I219V alteration in DNA mismatch repair activity and ulcerative colitis. 61
18200512 2008
11
Immune system alterations in patients with inflammatory bowel disease during remission. 61
18277086 2008
12
Novel genetic markers in inflammatory bowel disease. 61
17948929 2007
13
Clinical utility of wireless capsule endoscopy: experience with 200 cases. 61
16394875 2006
14
Association of cystic fibrosis with abnormalities in fatty acid metabolism. 61
14762183 2004
15
Autoimmunity in Wiskott-Aldrich syndrome: risk factors, clinical features, and outcome in a single-center cohort of 55 patients. 61
12728121 2003
16
[Social consequences and quality of life in patients with chronic inflammatory bowel disease]. 61
8701273 1996
17
Prospective study of the effect of resection of the rectum on male sexual function. 61
7190753 1980
18
Liver copper content in patients with inflammatory bowel disease and associated liver disorders. 61
531503 1979

Variations for Inflammatory Bowel Disease 9

Expression for Inflammatory Bowel Disease 9

Search GEO for disease gene expression data for Inflammatory Bowel Disease 9.

Pathways for Inflammatory Bowel Disease 9

Pathways related to Inflammatory Bowel Disease 9 according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.29 PLA2G4F PLA2G4E PLA2G4B
2
Show member pathways
12.24 PLA2G4F PLA2G4E PLA2G4B
3
Show member pathways
12.11 PLA2G4F PLA2G4E PLA2G4B
4
Show member pathways
12.02 PLA2G4F PLA2G4E PLA2G4B
5
Show member pathways
11.85 PLA2G4F PLA2G4E PLA2G4B
6
Show member pathways
11.78 PLA2G4F PLA2G4E PLA2G4B
7 11.64 PLA2G4F PLA2G4E PLA2G4B
8
Show member pathways
11.57 PLA2G4F PLA2G4E PLA2G4B
9 11.49 PLA2G4F PLA2G4E PLA2G4B
10 11.3 PLA2G4F PLA2G4E PLA2G4B
11
Show member pathways
11.21 PLA2G4F PLA2G4E
12 11.18 MST1 IL12B
13 10.91 PLA2G4F PLA2G4E PLA2G4B
14 10.49 PLA2G4F PLA2G4E PLA2G4B

GO Terms for Inflammatory Bowel Disease 9

Biological processes related to Inflammatory Bowel Disease 9 according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 lipid catabolic process GO:0016042 9.61 PLA2G4F PLA2G4E PLA2G4B
2 cellular response to organic cyclic compound GO:0071407 9.54 PLA2G4F NOD2
3 phospholipid metabolic process GO:0006644 9.54 PLA2G4F PLA2G4E PLA2G4B
4 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.52 NOD2 IL12B
5 positive regulation of tumor necrosis factor production GO:0032760 9.51 NOD2 IL12B
6 phosphatidylcholine acyl-chain remodeling GO:0036151 9.5 PLA2G4F PLA2G4E PLA2G4B
7 positive regulation of interleukin-10 production GO:0032733 9.49 NOD2 IL12B
8 phosphatidylinositol acyl-chain remodeling GO:0036149 9.48 PLA2G4F PLA2G4E
9 phosphatidylglycerol acyl-chain remodeling GO:0036148 9.46 PLA2G4F PLA2G4B
10 phosphatidylethanolamine acyl-chain remodeling GO:0036152 9.43 PLA2G4F PLA2G4E PLA2G4B
11 positive regulation of interleukin-17 production GO:0032740 9.4 NOD2 IL12B
12 phosphatidylserine acyl-chain remodeling GO:0036150 9.33 PLA2G4F PLA2G4E PLA2G4B
13 phospholipid catabolic process GO:0009395 9.13 PLA2G4F PLA2G4E PLA2G4B
14 glycerophospholipid catabolic process GO:0046475 8.8 PLA2G4F PLA2G4E PLA2G4B

Molecular functions related to Inflammatory Bowel Disease 9 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calcium-dependent phospholipid binding GO:0005544 9.5 PLA2G4F PLA2G4E PLA2G4B
2 phospholipase A2 activity GO:0004623 9.43 PLA2G4F PLA2G4E PLA2G4B
3 lysophospholipase activity GO:0004622 9.37 PLA2G4F PLA2G4B
4 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) GO:0102568 9.33 PLA2G4F PLA2G4E PLA2G4B
5 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) GO:0102567 9.13 PLA2G4F PLA2G4E PLA2G4B
6 calcium-dependent phospholipase A2 activity GO:0047498 8.8 PLA2G4F PLA2G4E PLA2G4B

Sources for Inflammatory Bowel Disease 9

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....