MCID: INF057
MIFTS: 27

Inflammatory Linear Verrucous Epidermal Nevus

Categories: Cancer diseases, Rare diseases, Skin diseases

Aliases & Classifications for Inflammatory Linear Verrucous Epidermal Nevus

MalaCards integrated aliases for Inflammatory Linear Verrucous Epidermal Nevus:

Name: Inflammatory Linear Verrucous Epidermal Nevus 54 60 74
Verrucous Epidermal Nevus 54 74
Verrucous Nevus 54 60
Ilven 54 60
Inflammatory Linear Verrucous Epidermal Naevus 54
Linear Verrucose Epidermal Nevus 54
Linear Verrucous Epidermal Nevus 74

Classifications:

Orphanet: 60  
Rare skin diseases


External Ids:

ICD10 via Orphanet 35 Q82.5
UMLS via Orphanet 75 C0362030 C0473574

Summaries for Inflammatory Linear Verrucous Epidermal Nevus

NIH Rare Diseases : 54 Inflammatory linear verrucous epidermal nevus (ILVEN) is a type of skin overgrowth, called epidermal nevus. It is characterized by skin colored, brown, or reddish, wart-like papules (nevi). The nevi join to form patches or plaques that often follow a pattern on the skin known as the "lines of Blaschko". The affected areas of the skin may be red, itchy, and inflamed. ILVEN typically presents from birth to early childhood and often is limited to one side of the lower half of the body. It affects females more often than males. It usually occurs alone; however, rarely ILVEN can be associated with other symptoms as part of an epidermal nevus syndrome. Rarely, ILVEN can become cancerous (for example, basal cell carcinoma or squamous cell carcinoma). ILVEN is caused by a genetic change that occurs after conception (somatic mutation). How this alteration leads to the signs and symptoms of ILVEN is not well understood. There is no one treatment or cure for ILVEN. Products used to soften the skin (emollients), moisturizers, and topical steroids may be utilized to relieve symptoms of dryness and itching. Recently, several patients have been treated with laser therapy with good results.

MalaCards based summary : Inflammatory Linear Verrucous Epidermal Nevus, also known as verrucous epidermal nevus, is related to verrucous nevus acanthokeratolytic and linear verrucous nevus syndrome. An important gene associated with Inflammatory Linear Verrucous Epidermal Nevus is CD8A (CD8a Molecule). Affiliated tissues include skin, testes and neutrophil.

Wikipedia : 77 Inflammatory Linear Verrucous Epidermal Nevus is a rare disease of the skin that presents as multiple,... more...

Related Diseases for Inflammatory Linear Verrucous Epidermal Nevus

Diseases related to Inflammatory Linear Verrucous Epidermal Nevus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 verrucous nevus acanthokeratolytic 12.3
2 linear verrucous nevus syndrome 12.2
3 palmoplantar keratoderma, epidermolytic 11.9
4 epidermolytic nevus 11.5
5 nevus, epidermal 11.1
6 psoriasis 10.7
7 neutrophil migration 10.4
8 pustulosis of palm and sole 10.4
9 lichen amyloidosis 10.3
10 burn scar 10.2
11 basal cell carcinoma 1 10.2
12 basal cell carcinoma 10.2
13 epidermolytic hyperkeratosis 10.2
14 erythrokeratodermia variabilis et progressiva 1 10.2
15 ichthyosis vulgaris 10.2
16 mycosis fungoides 10.2
17 psoriasis 7 10.2
18 psoriasis 11 10.2
19 psoriasis 13 10.2
20 nevoid hypermelanosis, linear and whorled 10.2
21 arthritis 10.2
22 vertebral artery occlusion 10.2
23 ichthyosis 10.2
24 squamous cell carcinoma 10.2
25 epilepsy 10.2
26 lichen planus 10.2
27 regional odontodysplasia 10.2
28 acanthosis nigricans 10.1
29 cowden syndrome 1 10.1
30 scoliosis 10.1
31 clear cell acanthoma 10.1
32 acanthoma 10.1
33 calcinosis 10.1
34 epidermolytic acanthoma 10.1
35 lymphatic malformations 10.1
36 phacomatosis pigmentokeratotica 10.1
37 precocious puberty 10.1
38 spitz nevus 10.1
39 woolly hair syndrome 10.1
40 porokeratotic eccrine ostial and dermal duct nevus 10.1
41 phakomatosis pigmentokeratotica 10.1
42 neurofibromatosis, type i 10.0
43 neurofibromatosis, type iv, of riccardi 10.0
44 congenital hemidysplasia with ichthyosiform erythroderma and limb defects 10.0

Graphical network of the top 20 diseases related to Inflammatory Linear Verrucous Epidermal Nevus:



Diseases related to Inflammatory Linear Verrucous Epidermal Nevus

Symptoms & Phenotypes for Inflammatory Linear Verrucous Epidermal Nevus

Drugs & Therapeutics for Inflammatory Linear Verrucous Epidermal Nevus

Search Clinical Trials , NIH Clinical Center for Inflammatory Linear Verrucous Epidermal Nevus

Genetic Tests for Inflammatory Linear Verrucous Epidermal Nevus

Anatomical Context for Inflammatory Linear Verrucous Epidermal Nevus

MalaCards organs/tissues related to Inflammatory Linear Verrucous Epidermal Nevus:

42
Skin, Testes, Neutrophil

Publications for Inflammatory Linear Verrucous Epidermal Nevus

Articles related to Inflammatory Linear Verrucous Epidermal Nevus:

(show top 50) (show all 121)
# Title Authors Year
1
Successful treatment of inflammatory linear verrucous epidermal nevus (ILVEN) with 308-nm excimer laser: patient patient required. ( 30648292 )
2019
2
Inflammatory linear verrucous epidermal nevus treated successfully with crisaborole ointment in a 5-year-old boy. ( 30838675 )
2019
3
A case of cutaneous horn arising in verrucous epidermal nevus. ( 29536972 )
2019
4
Successful Treatment of Inflammatory Linear Verrucous Epidermal Nevus with Concomitant Psoriasis Using Etanercept. ( 29606943 )
2018
5
Reconstruction of a buttock defect after excision of inflammatory linear verrucous epidermal nevus. ( 29624795 )
2018
6
Inflammatory linear verrucous epidermal nevus associated with erosive monoarthritis. ( 29974513 )
2018
7
Widely Spread Unilateral Inflammatory Linear Verrucous Epidermal Nevus (ILVEN). ( 30022937 )
2018
8
Treatment of inflammatory linear verrucous epidermal nevus pruritus with thalidomide. ( 30091521 )
2018
9
Inflammatory linear verrucous epidermal nevus responsive to 308-nm excimer laser treatment. ( 30235359 )
2018
10
Verruciform xanthoma overlying inflammatory linear verrucous epidermal nevus and in broad segmental distribution. ( 30337284 )
2018
11
Successful treatment of verrucous epidermal nevus with fractional micro-plasma radio-frequency technology and photodynamic therapy. ( 30130422 )
2018
12
Appearance of Verruca Over Linear Verrucous Epidermal Nevus - An Example of Locus Minoris Resistentiae: A Report of Three Cases. ( 30258804 )
2018
13
Dermoscopy of linear dermatosis along Blaschko's line in childhood: Lichen striatus versus inflammatory linear verrucous epidermal nevus. ( 28925078 )
2017
14
Is Ki-67, keratin 16, involucrin, and filaggrin immunostaining sufficient to diagnose inflammatory linear verrucous epidermal nevus? A report of eight cases and a comparison with psoriasis vulgaris. ( 29166506 )
2017
15
Inflammatory linear verrucous epidermal nevus: an unusual manifestation. ( 26426377 )
2017
16
Inflammatory Linear Verrucous Epidermal Nevus with a Postzygotic GJA1 Mutation Is a Mosaic Erythrokeratodermia Variabilis et Progressiva. ( 27890787 )
2017
17
A Case of "Inflammatory Linear Verrucous Epidermal Nevus" (ILVEN) Treated with CO2 Laser Ablation. ( 28785331 )
2017
18
Nevoid Psoriasis Coexisting with Verrucous Epidermal Nevus. ( 28405565 )
2017
19
Massive Vulvar Linear Verrucous Epidermal Nevus Presenting at Menarche. ( 28093318 )
2017
20
Dermoscopy of verrucous epidermal nevus: large brown circles as a novel feature for diagnosis. ( 26475079 )
2016
21
Squamous cell carcinoma arising in a multiple verrucous epidermal nevus. ( 28300931 )
2016
22
Basal cell carcinoma arising on a verrucous epidermal nevus: a case report. ( 25848348 )
2015
23
A Case of Inflammatory Linear Verrucous Epidermal Nevus on the Upper Eyelid. ( 26120188 )
2015
24
Genital/Perigenital Inflammatory Linear Verrucous Epidermal Nevus: A Case Series. ( 26677274 )
2015
25
Inflammatory linear verrucous epidermal nevus and regional odontodysplasia: A rare sorority. ( 26752881 )
2015
26
Precocious puberty in a 3-year-old child with systematized verrucous epidermal nevus. ( 25751347 )
2015
27
Bilateral Systematized Epidermolytic Verrucous Epidermal Nevus: A Rare Entity. ( 26288413 )
2015
28
Verrucous epidermal nevus (VEN) successfully treated with indocyanine green (ICG) photodynamic therapy (PDT). ( 27051764 )
2015
29
Treatment of inflammatory linear verrucous epidermal nevus with 2940 nm erbium fractional laser. ( 24112692 )
2014
30
Inflammatory linear verrucous epidermal nevus with psoriasiform histology. ( 24700964 )
2014
31
A novel technique used in the treatment of inflammatory linear verrucous epidermal nevus: tangential excision. ( 25192746 )
2014
32
The challenge to diagnose a clinical case of inflammatory linear verrucous epidermal nevus: is there any ILVEN associated with human papillomavirus infection? ( 25467274 )
2014
33
An atypical variant of phacomatosis pigmentokeratotica: verrucous epidermal nevus, speckled lentiginous nevus, and Spitz nevus associated with scoliosis. ( 24877171 )
2014
34
Porokeratotic eccrine ostial and dermal duct nevus with linear verrucous epidermal nevus: an unusual association. ( 24877174 )
2014
35
Linear non-epidermolytic verrucous epidermal nevus. ( 25031152 )
2014
36
A diagnostic dilemma: inflammatory linear verrucous epidermal nevus versus linear psoriasis. ( 23149170 )
2013
37
Inflammatory linear verrucous epidermal nevus and epilepsy: remission during valproic acid therapy. ( 23377323 )
2013
38
Is it inflammatory linear verrucous epidermal nevus or linear psoriasis? ( 23652072 )
2013
39
Inflammatory linear verrucous epidermal nevus: why a combined laser therapy. ( 23692514 )
2013
40
Inflammatory linear verrucous epidermal nevus in perineum and vulva: a report of two rare cases. ( 23716825 )
2013
41
Involucrin in the differential diagnosis between linear psoriasis and inflammatory linear verrucous epidermal nevus: a report of one case. ( 24068133 )
2013
42
Giant inflammatory linear verrucous epidermal nevus: successfully treated with full thickness excision and skin grafting. ( 24249899 )
2013
43
Vulvar and perianal condyloma superimposed inflammatory linear verrucous epidermal nevus: a case report and review of the literature. ( 24396613 )
2013
44
Inflammatory linear verrucous epidermal nevus. ( 24640220 )
2013
45
Treatment of verrucous epidermal nevus: experience with 71 cases. ( 23838611 )
2013
46
Analysis of mutations in the PIK3CA and FGFR3 genes in verrucous epidermal nevus. ( 24346875 )
2013
47
Verrucous epidermal nevus. ( 24364998 )
2013
48
Fatal metastatic cutaneous squamous cell carcinoma evolving from a localized verrucous epidermal nevus. ( 24403890 )
2013
49
Multiple basal cell carcinomas arising in a verrucous epidermal nevus. ( 23488626 )
2013
50
Dermacase. Can you identify this condition? Inflammatory linear verrucous epidermal nevus. ( 22423022 )
2012

Variations for Inflammatory Linear Verrucous Epidermal Nevus

Cosmic variations for Inflammatory Linear Verrucous Epidermal Nevus:

9 (show top 50) (show all 689)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM6926860 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.5825G>A p.G1942E 16:72796857-72796857 0
2 COSM6969201 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.11050G>A p.D3684N 16:72787226-72787226 0
3 COSM6953811 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.1991C>T p.S664F 16:72958155-72958155 0
4 COSM6926862 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.1261G>A p.G421R 16:72958885-72958885 0
5 COSM6936924 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.10847C>T p.S3616F 16:72787429-72787429 0
6 COSM3691166 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.2084C>T p.P695L 16:72958062-72958062 0
7 COSM6926861 ZFHX3 skin,NS,carcinoma,basal cell carcinoma c.1655C>T p.S552F 16:72958491-72958491 0
8 COSM212945 XPO1 skin,NS,carcinoma,basal cell carcinoma c.782G>A p.R261Q 2:61496985-61496985 0
9 COSM6936922 TSC2 skin,NS,carcinoma,basal cell carcinoma c.2060C>T p.S687F 16:2071897-2071897 0
10 COSM6926855 TSC2 skin,NS,carcinoma,basal cell carcinoma c.679T>A p.C227S 16:2056674-2056674 0
11 COSM6953809 TSC2 skin,NS,carcinoma,basal cell carcinoma c.869C>T p.P290L 16:2058767-2058767 0
12 COSM6912933 TRAF7 skin,NS,carcinoma,basal cell carcinoma c.1802C>T p.T601I 16:2176104-2176104 0
13 COSM6949578 TP63 skin,NS,carcinoma,basal cell carcinoma c.1922C>T p.A641V 3:189894381-189894381 0
14 COSM44071 TP53 skin,NS,carcinoma,basal cell carcinoma c.955A>G p.K319E 17:7673573-7673573 0
15 COSM44097 TP53 skin,NS,carcinoma,basal cell carcinoma c.530C>T p.P177L 17:7675082-7675082 0
16 COSM10812 TP53 skin,NS,carcinoma,basal cell carcinoma c.722C>T p.S241F 17:7674241-7674241 0
17 COSM10988 TP53 skin,NS,carcinoma,basal cell carcinoma c.772G>A p.E258K 17:7674191-7674191 0
18 COSM45074 TP53 skin,NS,carcinoma,basal cell carcinoma c.829T>G p.C277G 17:7673791-7673791 0
19 COSM10728 TP53 skin,NS,carcinoma,basal cell carcinoma c.839G>A p.R280K 17:7673781-7673781 0
20 COSM45739 TP53 skin,NS,carcinoma,basal cell carcinoma c.677G>C p.G226A 17:7674286-7674286 0
21 COSM44295 TP53 skin,NS,carcinoma,basal cell carcinoma c.993+1G>A p.? 17:7673534-7673534 0
22 COSM10939 TP53 skin,NS,carcinoma,basal cell carcinoma c.832C>T p.P278S 17:7673788-7673788 0
23 COSM10650 TP53 skin,NS,carcinoma,basal cell carcinoma c.529C>T p.P177S 17:7675083-7675083 0
24 COSM10662 TP53 skin,NS,carcinoma,basal cell carcinoma c.743G>A p.R248Q 17:7674220-7674220 0
25 COSM43665 TP53 skin,NS,carcinoma,basal cell carcinoma c.746G>C p.R249T 17:7674217-7674217 0
26 COSM45774 TP53 skin,NS,carcinoma,basal cell carcinoma c.899C>G p.P300R 17:7673721-7673721 0
27 COSM10749 TP53 skin,NS,carcinoma,basal cell carcinoma c.830G>T p.C277F 17:7673790-7673790 0
28 COSM10660 TP53 skin,NS,carcinoma,basal cell carcinoma c.818G>A p.R273H 17:7673802-7673802 0
29 COSM11449 TP53 skin,NS,carcinoma,basal cell carcinoma c.388C>T p.L130F 17:7675224-7675224 0
30 COSM10771 TP53 skin,NS,carcinoma,basal cell carcinoma c.749C>T p.P250L 17:7674214-7674214 0
31 COSM44068 TP53 skin,NS,carcinoma,basal cell carcinoma c.532C>A p.H178N 17:7675080-7675080 0
32 COSM11152 TP53 skin,NS,carcinoma,basal cell carcinoma c.700T>C p.Y234H 17:7674263-7674263 0
33 COSM10768 TP53 skin,NS,carcinoma,basal cell carcinoma c.535C>T p.H179Y 17:7675077-7675077 0
34 COSM45834 TP53 skin,NS,carcinoma,basal cell carcinoma c.409C>A p.L137M 17:7675203-7675203 0
35 COSM10654 TP53 skin,NS,carcinoma,basal cell carcinoma c.637C>T p.R213* 17:7674894-7674894 0
36 COSM10905 TP53 skin,NS,carcinoma,basal cell carcinoma c.451C>T p.P151S 17:7675161-7675161 0
37 COSM6932 TP53 skin,NS,carcinoma,basal cell carcinoma c.733G>A p.G245S 17:7674230-7674230 0
38 COSM10648 TP53 skin,NS,carcinoma,basal cell carcinoma c.524G>A p.R175H 17:7675088-7675088 0
39 COSM45424 TP53 skin,NS,carcinoma,basal cell carcinoma c.781A>T p.S261C 17:7674182-7674182 0
40 COSM10656 TP53 skin,NS,carcinoma,basal cell carcinoma c.742C>T p.R248W 17:7674221-7674221 0
41 COSM10659 TP53 skin,NS,carcinoma,basal cell carcinoma c.817C>T p.R273C 17:7673803-7673803 0
42 COSM10794 TP53 skin,NS,carcinoma,basal cell carcinoma c.796G>A p.G266R 17:7673824-7673824 0
43 COSM43582 TP53 skin,NS,carcinoma,basal cell carcinoma c.454C>T p.P152S 17:7675158-7675158 0
44 COSM10704 TP53 skin,NS,carcinoma,basal cell carcinoma c.844C>T p.R282W 17:7673776-7673776 0
45 COSM6549 TP53 skin,NS,carcinoma,basal cell carcinoma c.743G>T p.R248L 17:7674220-7674220 0
46 COSM10726 TP53 skin,NS,carcinoma,basal cell carcinoma c.856G>A p.E286K 17:7673764-7673764 0
47 COSM45304 TP53 skin,NS,carcinoma,basal cell carcinoma c.375+1G>A p.? 17:7675993-7675993 0
48 COSM10867 TP53 skin,NS,carcinoma,basal cell carcinoma c.797G>A p.G266E 17:7673823-7673823 0
49 COSM43714 TP53 skin,NS,carcinoma,basal cell carcinoma c.836G>A p.G279E 17:7673784-7673784 0
50 COSM44226 TP53 skin,NS,carcinoma,basal cell carcinoma c.380C>T p.S127F 17:7675232-7675232 0

Expression for Inflammatory Linear Verrucous Epidermal Nevus

Search GEO for disease gene expression data for Inflammatory Linear Verrucous Epidermal Nevus.

Pathways for Inflammatory Linear Verrucous Epidermal Nevus

GO Terms for Inflammatory Linear Verrucous Epidermal Nevus

Sources for Inflammatory Linear Verrucous Epidermal Nevus

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