MCID: INF018
MIFTS: 26

Inflammatory Liposarcoma

Categories: Cancer diseases, Rare diseases

Aliases & Classifications for Inflammatory Liposarcoma

MalaCards integrated aliases for Inflammatory Liposarcoma:

Name: Inflammatory Liposarcoma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:8233
NCIt 50 C6508
SNOMED-CT 67 28655007
UMLS 70 C1370890

Summaries for Inflammatory Liposarcoma

MalaCards based summary : Inflammatory Liposarcoma is related to pleomorphic lipoma and liposarcoma. An important gene associated with Inflammatory Liposarcoma is EIF5B (Eukaryotic Translation Initiation Factor 5B), and among its related pathways/superpathways are Oncogene Induced Senescence and TP53 Network. Affiliated tissues include breast, heart and skin, and related phenotype is neoplasm.

Related Diseases for Inflammatory Liposarcoma

Diseases in the Liposarcoma family:

Adult Liposarcoma Inflammatory Liposarcoma

Diseases related to Inflammatory Liposarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 143)
# Related Disease Score Top Affiliating Genes
1 pleomorphic lipoma 30.6 MDM2 CD34
2 liposarcoma 30.3 MDM2 CDKN2A CD34
3 lipomatosis, multiple 30.3 MDM2 CD34
4 well-differentiated liposarcoma 30.0 MDM2 CDKN2A CD34
5 inflammatory myofibroblastic tumor 29.7 MDM2 CD34 ALK
6 spindle cell sarcoma 29.3 MDM2 CD34
7 lymphoma, non-hodgkin, familial 29.2 MME MDM2 CD34 ALK
8 paratesticular lipoma 10.2 MDM2 ALK
9 lipoma of spermatic cord 10.2 MDM2 ALK
10 parameningeal embryonal rhabdomyosarcoma 10.2 MDM2 ALK
11 angiolipoma 10.2 MDM2 CD34
12 aortic malignant tumor 10.2 MDM2 CD34
13 sclerosing liposarcoma 10.2 MDM2 CD34
14 gastric liposarcoma 10.2 MDM2 CD34
15 infiltrating lipoma 10.2 MDM2 CD34
16 spindle cell liposarcoma 10.2 MDM2 CD34
17 pediatric liposarcoma 10.2 MDM2 CD34
18 liposarcoma of bone 10.2 MDM2 CD34
19 mixed liposarcoma 10.2 MDM2 CD34
20 heart sarcoma 10.2 MDM2 CD34
21 extraosseous osteosarcoma 10.2 MDM2 CD34
22 retroperitoneal sarcoma 10.2 MDM2 CD34
23 malignant mesenchymoma 10.2 MDM2 CD34
24 spindle cell lipoma 10.1 MDM2 CD34
25 heart lymphoma 10.1 MME ALK
26 benign fibrous mesothelioma 10.1 CD34 ALK
27 conventional fibrosarcoma 10.1 MDM2 CD34
28 liver leiomyoma 10.1 CD34 ALK
29 bone lymphoma 10.1 MME ALK
30 breast lymphoma 10.1 MME ALK
31 mediastinum liposarcoma 10.1 MDM2 CDKN2A
32 acantholytic acanthoma 10.1 MME ALK
33 intravascular fasciitis 10.1 CD34 ALK
34 heart cancer 10.1 MDM2 CD34
35 esophagus verrucous carcinoma 10.1 MDM2 CDKN2A
36 verrucous carcinoma 10.1 MDM2 CDKN2A
37 conventional angiosarcoma 10.1 OSCAR CD34
38 pancreas sarcoma 10.1 MDM2 CDKN2A
39 pediatric lymphoma 10.1 MME ALK
40 adult lymphoma 10.1 MME ALK
41 hereditary melanoma 10.1 MDM2 CDKN2A
42 ovarian brenner tumor 10.1 MDM2 CDKN2A
43 breast leiomyoma 10.1 MME CD34
44 breast myofibroblastoma 10.1 MME CD34
45 pacinian tumor 10.1 MME CD34
46 maxillary sinus benign neoplasm 10.1 CDKN2A ALK
47 mucocele of appendix 10.1 MME CD34
48 pediatric fibrosarcoma 10.1 CD34 ALK
49 malignant spiradenoma 10.1 MDM2 CDKN2A
50 cervical polyp 10.1 MME CD34

Graphical network of the top 20 diseases related to Inflammatory Liposarcoma:



Diseases related to Inflammatory Liposarcoma

Symptoms & Phenotypes for Inflammatory Liposarcoma

MGI Mouse Phenotypes related to Inflammatory Liposarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.02 ALK CD34 CDKN2A CYGB MDM2

Drugs & Therapeutics for Inflammatory Liposarcoma

Search Clinical Trials , NIH Clinical Center for Inflammatory Liposarcoma

Genetic Tests for Inflammatory Liposarcoma

Anatomical Context for Inflammatory Liposarcoma

MalaCards organs/tissues related to Inflammatory Liposarcoma:

40
Breast, Heart, Skin, Bone, Smooth Muscle, Skeletal Muscle, Liver

Publications for Inflammatory Liposarcoma

Articles related to Inflammatory Liposarcoma:

(show all 18)
# Title Authors PMID Year
1
[Dedifferentiated liposarcoma with inflammatory myofibroblastic tumor-like features: a clinicopathological analysis of five cases]. 61
30955263 2019
2
Well-differentiated inflammatory liposarcoma with metastasis in a 6-y-old cat. 61
28782430 2017
3
Surgical resection of a well-differentiated inflammatory liposarcoma of the middle mediastinum: a case report. 61
28932587 2017
4
[A Case of Perirenal Inflammatory Liposarcoma]. 61
26087820 2015
5
Giant inflammatory variant of well differentiated liposarcoma: a case report of a rare entity. 61
24086890 2013
6
Retroperitoneal inflammatory liposarcoma in a patient with non-hodgkin lymphoma: a report highlighting diagnostic pitfalls. 61
21188206 2010
7
Detection of MDM2 gene amplification or protein expression distinguishes sclerosing mesenteritis and retroperitoneal fibrosis from inflammatory well-differentiated liposarcoma. 61
18836421 2009
8
Retroperitoneal well-differentiated inflammatory liposarcoma: a diagnostic dilemma. 61
18770006 2008
9
[Retroperitoneal well-differentiated inflammatory liposarcoma]. 61
17568358 2007
10
[Well-differentiated inflammatory liposarcoma occurring in the scrotum: a case report]. 61
17252983 2006
11
Inflammatory variant of a well-differentiated retroperitoneal liposarcoma: case report of a rare giant variety. 61
16763361 2006
12
Pathologic quiz case: a large recurrent thigh mass in a 79-year-old woman. Inflammatory liposarcoma occurring as a component of a recurrent, well-differentiated, lipoma-like liposarcoma. 61
14692832 2004
13
Well-differentiated liposarcoma (atypical lipomatous tumors). 61
11757865 2001
14
Well-differentiated inflammatory liposarcoma presenting as pyrexia of unknown origin. 61
11573568 2001
15
[Well differentiated inflammatory subcutaneous liposarcoma (inflammatory atypical lipomatous tumor)]. 61
10677913 1999
16
Fine-needle aspiration cytology of well-differentiated inflammatory liposarcoma: a case report with histologic follow-up. 61
10204107 1999
17
Lymphocyte-rich well-differentiated liposarcoma: report of nine cases. 61
9255251 1997
18
Well-differentiated inflammatory liposarcoma: an uncommon and easily overlooked variant of a common sarcoma. 61
9158675 1997

Variations for Inflammatory Liposarcoma

Expression for Inflammatory Liposarcoma

Search GEO for disease gene expression data for Inflammatory Liposarcoma.

Pathways for Inflammatory Liposarcoma

Pathways related to Inflammatory Liposarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.66 MDM2 CDKN2A
2
Show member pathways
10.3 MDM2 CDKN2A
3 9.97 MDM2 CDKN2A

GO Terms for Inflammatory Liposarcoma

Biological processes related to Inflammatory Liposarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein destabilization GO:0031648 9.16 MDM2 CDKN2A
2 replicative senescence GO:0090399 8.96 MME CDKN2A
3 amyloid fibril formation GO:1990000 8.62 MDM2 CDKN2A

Molecular functions related to Inflammatory Liposarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 disordered domain specific binding GO:0097718 8.96 MDM2 CDKN2A
2 SUMO transferase activity GO:0019789 8.62 MDM2 CDKN2A

Sources for Inflammatory Liposarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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