MCID: INF018
MIFTS: 27

Inflammatory Liposarcoma

Categories: Cancer diseases, Rare diseases

Aliases & Classifications for Inflammatory Liposarcoma

MalaCards integrated aliases for Inflammatory Liposarcoma:

Name: Inflammatory Liposarcoma 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:8233
NCIt 51 C6508
SNOMED-CT 69 28655007
UMLS 74 C1370890

Summaries for Inflammatory Liposarcoma

MalaCards based summary : Inflammatory Liposarcoma is related to liposarcoma and sclerosing liposarcoma. An important gene associated with Inflammatory Liposarcoma is MDM2 (MDM2 Proto-Oncogene), and among its related pathways/superpathways are Viral carcinogenesis and Cellular senescence (KEGG). Affiliated tissues include bone, skin and t cells, and related phenotype is neoplasm.

Related Diseases for Inflammatory Liposarcoma

Diseases in the Liposarcoma family:

Adult Liposarcoma Inflammatory Liposarcoma

Diseases related to Inflammatory Liposarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
# Related Disease Score Top Affiliating Genes
1 liposarcoma 30.0 CD34 CDKN2A MDM2
2 sclerosing liposarcoma 10.1 CD34 MDM2
3 conventional fibrosarcoma 10.1 CD34 MDM2
4 mixed liposarcoma 10.1 CD34 MDM2
5 spindle cell liposarcoma 10.1 CD34 MDM2
6 periosteal osteogenic sarcoma 10.1 CD34 MDM2
7 infiltrating lipoma 10.1 CD34 MDM2
8 muscle cancer 10.0 CD34 MDM2
9 connective tissue cancer 10.0 CD34 MDM2
10 vulvar dystrophy 10.0 CD34 CDKN2A
11 infiltrating angiolipoma 10.0 CDKN2A MDM2
12 atypical lipomatous tumor 10.0 CDKN2A MDM2
13 atypical neurofibroma 10.0 CD34 CDKN2A
14 neurofibroma 10.0 CD34 CDKN2A
15 periosteal chondrosarcoma 10.0 CDKN2A MDM2
16 pleomorphic liposarcoma 10.0 CDKN2A MDM2
17 well-differentiated liposarcoma 10.0 CDKN2A MDM2
18 dedifferentiated liposarcoma 10.0 CDKN2A MDM2
19 verrucous carcinoma 10.0 CDKN2A MDM2
20 fibrosarcoma of bone 10.0 CDKN2A MDM2
21 retinal cancer 10.0 CDKN2A MDM2
22 supratentorial cancer 10.0 CDKN2A MDM2
23 cerebrum cancer 10.0 CDKN2A MDM2
24 ocular cancer 10.0 CDKN2A MDM2
25 cell type benign neoplasm 10.0 CD34 CDKN2A
26 grade iii astrocytoma 10.0 CDKN2A MDM2
27 skin melanoma 9.9 CDKN2A MDM2
28 salivary gland carcinoma 9.9 CDKN2A MDM2
29 malignant peripheral nerve sheath tumor 9.9 CDKN2A MDM2
30 li-fraumeni syndrome 9.9 CDKN2A MDM2
31 gastrointestinal system cancer 9.9 CD34 CDKN2A
32 adult medulloblastoma 9.9 EIF5B MDM2
33 precursor t-cell acute lymphoblastic leukemia 9.9 CD34 CDKN2A
34 meningioma, familial 9.9 CD34 CDKN2A
35 mantle cell lymphoma 9.8 CDKN2A MDM2
36 lipomatosis, multiple 9.8
37 lymphoma, hodgkin, classic 9.8
38 lymphoma, non-hodgkin, familial 9.8
39 lymphoma 9.8
40 pleomorphic lipoma 9.8
41 sarcoma 9.8
42 gastrointestinal stromal tumor 9.8 CD34 CDKN2A
43 ischemic fasciitis 9.7 CD34 CDKN2A MDM2
44 cellular schwannoma 9.7 CD34 CDKN2A MDM2
45 nervous system cancer 9.7 CD34 CDKN2A MDM2
46 adamantinoma of long bones 9.7 CDKN2A MDM2
47 large intestine cancer 9.7 CD34 CDKN2A MDM2
48 ewing sarcoma 9.6 CD34 CDKN2A MDM2
49 myeloma, multiple 9.6 CD34 CDKN2A

Graphical network of the top 20 diseases related to Inflammatory Liposarcoma:



Diseases related to Inflammatory Liposarcoma

Symptoms & Phenotypes for Inflammatory Liposarcoma

MGI Mouse Phenotypes related to Inflammatory Liposarcoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.8 CD34 CDKN2A MDM2

Drugs & Therapeutics for Inflammatory Liposarcoma

Search Clinical Trials , NIH Clinical Center for Inflammatory Liposarcoma

Genetic Tests for Inflammatory Liposarcoma

Anatomical Context for Inflammatory Liposarcoma

MalaCards organs/tissues related to Inflammatory Liposarcoma:

42
Bone, Skin, T Cells, Salivary Gland

Publications for Inflammatory Liposarcoma

Articles related to Inflammatory Liposarcoma:

# Title Authors Year
1
Well-differentiated inflammatory liposarcoma with metastasis in a 6-y-old cat. ( 28782430 )
2017
2
Surgical resection of a well-differentiated inflammatory liposarcoma of the middle mediastinum: a case report. ( 28932587 )
2017
3
Retroperitoneal inflammatory liposarcoma in a patient with non-hodgkin lymphoma: a report highlighting diagnostic pitfalls. ( 21188206 )
2010
4
Retroperitoneal well-differentiated inflammatory liposarcoma: a diagnostic dilemma. ( 18770006 )
2008
5
Pathologic quiz case: a large recurrent thigh mass in a 79-year-old woman. Inflammatory liposarcoma occurring as a component of a recurrent, well-differentiated, lipoma-like liposarcoma. ( 14692832 )
2004
6
Well-differentiated inflammatory liposarcoma presenting as pyrexia of unknown origin. ( 11573568 )
2001
7
Fine-needle aspiration cytology of well-differentiated inflammatory liposarcoma: a case report with histologic follow-up. ( 10204107 )
1999
8
Well-differentiated inflammatory liposarcoma: an uncommon and easily overlooked variant of a common sarcoma. ( 9158675 )
1997

Variations for Inflammatory Liposarcoma

Expression for Inflammatory Liposarcoma

Search GEO for disease gene expression data for Inflammatory Liposarcoma.

Pathways for Inflammatory Liposarcoma

GO Terms for Inflammatory Liposarcoma

Biological processes related to Inflammatory Liposarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.43 CD34 CDKN2A MDM2
2 protein destabilization GO:0031648 9.16 CDKN2A MDM2
3 protein sumoylation GO:0016925 8.96 CDKN2A MDM2
4 amyloid fibril formation GO:1990000 8.62 CDKN2A MDM2

Molecular functions related to Inflammatory Liposarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 disordered domain specific binding GO:0097718 8.96 CDKN2A MDM2
2 SUMO transferase activity GO:0019789 8.62 CDKN2A MDM2

Sources for Inflammatory Liposarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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