Inflammatory Myofibroblastic Tumor disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: INF058 MIFTS: 48	Inflammatory Myofibroblastic Tumor Categories: Rare diseases, Cancer diseases
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Aliases & Classifications for Inflammatory Myofibroblastic Tumor

MalaCards integrated aliases for Inflammatory Myofibroblastic Tumor:

Name: Inflammatory Myofibroblastic Tumor ¹² ⁵³ ⁵⁹ ¹⁵ ⁷³

Inflammatory Fibrosarcoma ⁵³

Classifications:

MalaCards categories:
Global: Rare diseases Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0050905

Orphanet ⁵⁹ ORPHA178342

UMLS via Orphanet ⁷⁴ C0334121

UMLS ⁷³ C0334121

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Summaries for Inflammatory Myofibroblastic Tumor

NIH Rare Diseases : ⁵³ An inflammatory myofibroblastic tumor (IMT) is an uncommon, usually benign (non-cancerous) tumor made up of cells called myofibroblastic spindle cells. It usually develops in children or young adults, but can affect people of any age. An IMT can occur in almost any part of the body but is most commonly found in the lung, orbit (eye socket), peritoneum (lining of the abdominal cavity and internal organs), and mesentery. Signs and symptoms vary depending on the site of the tumor. Some people with an IMT are asymptomatic, while others may have nonspecific respiratory symptoms, fever, or pain. IMTs may recur, and become locally invasive and/or spread (metastasize) to other parts of the body. However, malignant (cancerous) IMTs are rare. The underlying cause of IMTs is poorly understood. Some cases have been linked to translocations involving the ALK gene. Treatment involves surgical removal when possible, although there are reports of treatment with oral steroids and radiation therapy.

MalaCards based summary : Inflammatory Myofibroblastic Tumor, also known as inflammatory fibrosarcoma, is related to infantile myofibromatosis and anaplastic large cell lymphoma, and has symptoms including fever and pain. An important gene associated with Inflammatory Myofibroblastic Tumor is ALK (ALK Receptor Tyrosine Kinase), and among its related pathways/superpathways are Innate Immune System and Endometrial cancer. The drugs Cyclophosphamide and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include lung, eye and liver, and related phenotype is Reduced mammosphere formation.

Disease Ontology : ¹² A mesenchymal cell neoplasm that has material basis in myofibroblastic cells admixed with inflammatory cells.

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Related Diseases for Inflammatory Myofibroblastic Tumor

Diseases related to Inflammatory Myofibroblastic Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 212)

#	Related Disease	Score	Top Affiliating Genes
1	infantile myofibromatosis	32.9	ACTC1 DES VIM
2	anaplastic large cell lymphoma	31.0	ALK NPM1 RNF213
3	spindle cell carcinoma	30.7	ACTC1 DES VIM
4	fibrous histiocytoma	30.5	ACTC1 DES S100B VIM
5	fibromatosis	30.4	ACTC1 DES KIT VIM
6	dedifferentiated liposarcoma	30.3	ACTC1 DES MDM2 TP53
7	liposarcoma	30.2	DES MDM2 TP53 VIM
8	histiocytoma	30.0	ALK KIT MDM2 TP53
9	dendritic cell tumor	29.9	ACTC1 CR1 CR2 S100B VIM
10	malignant fibroxanthoma	29.7	ACTC1 ALK DES MDM2 S100B VIM
11	rhabdomyosarcoma	29.6	ACTC1 ALK DES MDM2 TP53 VIM
12	gastrointestinal stromal tumor	28.7	ACTC1 CCND1 DES KIT S100B TP53
13	liver inflammatory pseudotumor	11.2
14	desmoid tumor	11.1
15	lymphangiectasis	11.0	ACTC1 VIM
16	infantile digital fibromatosis	11.0	DES VIM
17	glomangiomyoma	11.0	ACTC1 VIM
18	fibroblastic rheumatism	11.0	ACTC1 DES
19	hydromyelia	11.0	S100B VIM
20	lymphangiomatosis	11.0	DES VIM
21	intravascular papillary endothelial hyperplasia	10.9	ACTC1 VIM
22	cutaneous leiomyosarcoma	10.9	ACTC1 DES
23	bednar tumor	10.9	S100B VIM
24	primitive neuroectodermal tumor of the cervix uteri	10.9	DES VIM
25	malignant giant cell tumor of soft parts	10.9	ACTC1 S100B
26	botryoid rhabdomyosarcoma	10.9	ACTC1 DES
27	malignant triton tumor	10.9	DES S100B
28	reticular perineurioma	10.9	KIT S100B
29	angiolipoma	10.9	ACTC1 DES VIM
30	parachordoma	10.9	ACTC1 DES VIM
31	epithelioid leiomyosarcoma	10.9	ACTC1 DES VIM
32	parameningeal embryonal rhabdomyosarcoma	10.9	ALK TP53
33	benign metastasizing leiomyoma	10.9	ACTC1 DES VIM
34	congenital fibrosarcoma	10.8	ACTC1 DES VIM
35	angiocentric glioma	10.8	ACTC1 S100B VIM
36	rhabdoid cancer	10.8	ACTC1 DES VIM
37	primary hepatic neuroendocrine carcinoma	10.8	S100B VIM
38	syringoma	10.8	DES S100B VIM
39	fasciitis	10.8	ACTC1 DES VIM
40	mast-cell sarcoma	10.8	KIT VIM
41	juvenile xanthogranuloma	10.8	DES S100B VIM
42	parapharyngeal meningioma	10.8	CR1 CR2
43	glomangioma	10.8	ACTC1 DES VIM
44	myopericytoma	10.8	ACTC1 S100B
45	ovarian fibrothecoma	10.8	ACTC1 DES KIT
46	granular cell tumor	10.8	DES S100B VIM
47	gallbladder sarcoma	10.8	DES KIT
48	myoepithelioma	10.8	ACTC1 S100B VIM
49	acute myeloblastic leukemia with maturation	10.8	KIT NPM1
50	pulmonary vein stenosis	10.8	ACTC1 DES KIT

Graphical network of the top 20 diseases related to Inflammatory Myofibroblastic Tumor:

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Symptoms & Phenotypes for Inflammatory Myofibroblastic Tumor

UMLS symptoms related to Inflammatory Myofibroblastic Tumor:

fever, pain

GenomeRNAi Phenotypes related to Inflammatory Myofibroblastic Tumor according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Reduced mammosphere formation	GR00396-S	9.17	CARS CCND1 CLTC DES MDM2 RANBP2

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Drugs & Therapeutics for Inflammatory Myofibroblastic Tumor

Drugs for Inflammatory Myofibroblastic Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Cyclophosphamide

Approved, Investigational

Phase 2, Phase 3

50-18-0, 6055-19-2

2907

Synonyms:

(-)-Cyclophosphamide

(+-)-Cyclophosphamide

(RS)-Cyclophosphamide

1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine

1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin

2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide

4-Hydroxy-cyclophosphan-mamophosphatide

50-18-0

60007-95-6

6055-19-2 (monohydrate)

75526-90-8

AC1L1EQQ

AI3-26198

Anhydrous cyclophosphamide

Anhydrous, cyclophosphamide

ASTA

Asta B 518

ASTA B518

B 518

B-518

bis(2-Chloroethyl)phosphami de cyclic propanolamide

bis(2-Chloroethyl)phosphamide cyclic propanolamide ester

Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester

BRN 0011744

BSPBio_002099

C 0768

C07888

C7H15Cl2N2O2P

CB 4564

CB-4564

CCRIS 188

CHEBI:4027

CHEMBL32520

CHEMBL88

Ciclofosfamida

Ciclofosfamida [INN-Spanish]

Ciclofosfamide

Ciclophosphamide

Ciclophosphamide [INN]

CID2907

Clafen

Claphene

CPA

CTX

Cycloblastin

Cyclophosphamid

cyclophosphamide

Cyclophosphamide

Cyclophosphamide (anhydrous form)

Cyclophosphamide (anhydrous)

Cyclophosphamide (INN)

Cyclophosphamide (TN)

Cyclophosphamide anhydrous

Cyclophosphamide monohydrate

Cyclophosphamide Monohydrate

Cyclophosphamide Sterile

Cyclophosphamide, (+-)-Isomer

Cyclophosphamide, (R)-isomer

Cyclophosphamide, (S)-isomer

Cyclophosphamides

Cyclophosphamidum

Cyclophosphamidum [INN-Latin]

Cyclophosphan

Cyclophosphane

Cyclophosphanum

Cyclophosphoramide

Cyclostin

Cyklofosfamid

Cyklofosfamid [Czech]

Cytophosphan

Cytophosphane

Cytoxan

Cytoxan (TN)

Cytoxan Lyoph

D,L-Cyclophosphamide

D07760

DB00531

DivK1c_000246

EINECS 200-015-4

Endoxan

Endoxan R

Endoxana

Endoxanal

Endoxan-Asta

Endoxane

Enduxan

EU-0100238

Genoxal

Hexadrin

HMS2090A12

HSDB 3047

IDI1_000246

KBio1_000246

KBio2_001338

KBio2_003906

KBio2_006474

KBio3_001319

KBioGR_000888

KBioSS_001338

Ledoxina

Lopac0_000238

Lopac-C-0768

LS-1302

LS-99787

Lyophilized Cytoxan

Mitoxan

MolPort-001-783-420

Monohydrate, cyclophosphamide

N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide

N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

NCGC00015209-01

NCGC00015209-03

NCGC00015209-06

NCGC00091741-02

NCGC00091741-03

NCI60_002097

NCI-C04900

Neosar

NINDS_000246

NSC 26271

NSC26271

NSC-26271

NSC273033

NSC273034

Occupation, cyclophosphamide exposure

Procytox

RCRA waste no. U058

Rcra waste number U058

Rcra Waste Number U058

Revimmune

S1217_Selleck

Semdoxan

Sendoxan

Senduxan

SK 20501

SPBio_001071

Spectrum_000858

Spectrum2_001146

Spectrum3_000370

Spectrum4_000304

Spectrum5_000795

STK177249

STOCK2S-91217

UNII-6UXW23996M

WLN: T6MPOTJ BO BN2G2G

Zyklophosphamid

Zyklophosphamid [German]

Doxorubicin

Approved, Investigational

Phase 2, Phase 3

23214-92-8

31703

Synonyms:

(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranoside

(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside

(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside

(8S-cis)-10-((3-amino-2,3,6-Trideoxy-a-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

(8S-cis)-10-((3-amino-2,3,6-Trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

(8S-cis)-10-((3-amino-2,3,6-Trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

111266-55-8

14-hydroxydaunomycin

14-Hydroxydaunomycin

14-hydroxydaunorubicine

14-Hydroxydaunorubicine

23214-92-8

23257-17-2

24385-08-8

25311-50-6

25316-40-9

25316-40-9 (hydrochloride)

29042-30-6

AC1L1M5T

AC1Q29OJ

adiblastine (hydrochloride salt)

ADM

ADR

adr iablatina (hydrochloride salt)

Adriablastin

Adriablastine

adriablastine (hydrochloride salt)

adriablatina (hydrochloride salt)

Adriacin (hydrochloride salt)

Adriamycin

Adriamycin PFS

Adriamycin PFS (hydrochloride salt)

Adriamycin RDF

Adriamycin RDF (hydrochloride salt)

Adriamycin semiquinone

Adriamycin Semiquinone

Adriblas tina

Adriblastin

Adriblastina

Adriblastina (hydrochloride salt)

Adriblastina (TN)

Adriblastine

adriblatina (hydrochloride salt)

Adrimedac

Aerosolized Doxorubicin

Baxter brand OF doxorubicin hydrochloride

Bedford brand OF doxorubicin hydrochloride

BPBio1_000502

BRD-K92093830-003-04-3

Bristol-myers squibb brand OF doxorubicin hydrochloride

BSPBio_000456

BSPBio_001031

C01661

C27H29NO11

Caelyx

CCRIS 739

Cell pharm brand OF doxorubicin hydrochloride

CHEBI:28748

CHEMBL179

CID31703

Columbia brand OF doxorubicin hydrochloride

Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74

Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120

D03899

DB00997

DM2

Doxil

Doxo

doxo Cell

doxo-Cell

Doxolem

doxorubicin

Doxorubicin

Doxorubicin (USAN/INN)

Doxorubicin [USAN:INN:BAN]

Doxorubicin citrate

Doxorubicin HCl

Doxorubicin hexal

Doxorubicin hydrochloride

Doxorubicin Hydrochloride

Doxorubicin hydrochloride (hydrochloride salt)

Doxorubicin NC

Doxorubicina

Doxorubicina [INN-Spanish]

Doxorubicina ferrer farm

Doxorubicina funk

Doxorubicina tedec

Doxorubicine

Doxorubicine [INN-French]

Doxorubicine baxter

Doxorubicin-hLL1

Doxorubicin-hLL1 conjugate

Doxorubicin-P4/D10

Doxorubicin-P4/D10 conjugate

Doxorubicinum

Doxorubicinum [INN-Latin]

Doxotec

DOX-SL

EINECS 245-495-6

Elan brand OF doxorubicin hydrochloride

Farmablastina (hydrochloride salt)

Farmiblastina

Ferrer brand OF doxorubicin hydrochloride

FI 106

Hexal brand OF doxorubicin hydrochloride

HMS2089H06

HSDB 3070

Hydrochloride, doxorubicin

Hydroxydaunomycin hydrochlor ide (hydrochloride salt)

Hydroxydaunomycin hydrochloride (hydrochloride salt)

Hydroxydaunorubicin

Hydroxydaunorubicin hydrochloride (hydrochloride salt)

JT9100000

Kenfarma brand OF doxorubicin hydrochloride

Lemery brand OF doxorubicin hydrochloride

LMPK13050001

LS-1029

LS-165655

Medac brand OF doxorubicin hydrochloride

MLS000759533

Myocet

NChemBio.2007.10-comp13

nchembio809-comp5

NCI-C01514

NDC 38242-874

Neocorp brand OF doxorubicin hydrochloride

NIOSH/JT9100000

NSC 123127

Onkodox

Onkoworks brand OF doxorubicin hydrochloride

Pfizer brand OF doxorubicin hydrochloride

Prasfarma brand OF doxorubicin hydrochloride

Prestwick0_000438

Prestwick1_000438

Prestwick2_000438

Prestwick3_000438

Probes1_000151

Probes2_000129

RDF Rubex

Resmycin

Ribodoxo

Ribosepharm brand OF doxorubicin hydrochloride

Rubex

Rubex (hydrochloride salt)

SMP1_000106

SPBio_002395

Tedec meiji brand OF doxorubicin hydrochloride

ThermoDox

TLC D-99

Triferric doxorubicin

UNII-80168379AG

Urokit doxo cell

Urokit doxo-cell

Ifosfamide

Approved

Phase 2, Phase 3

3778-73-2

3690

Synonyms:

(+-)-Ifosfamid

(+-)-Ifosphamide

(+-)-Tetrahydro-N,3-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

(D,L)-Ifosfamide

(R,S)-Ifosphamide

(R,S)-N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

{3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,

1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide

1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide

2,3-(N,N(sup 1)-Bis(2-chloroethyl)diamido)-1,3,2-oxazaphosphoridinoxyd

2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd

2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis( 2-chloroethyl)tetrahydro-, 2-oxide

2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide

2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide

2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide (8CI)

2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide

3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine oxide

3-(2-Chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide

3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorine oxide

3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide

3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2- oxide

3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide

3,} 2-oxazaphosphorine oxide

36341-88-5

3778-73-2

84711-20-6

A 4942

AB00513932

AC1L1GHW

AC-2113

Ambap3778-73-2

Asta Z 4942

ASTA Z 4942

BPBio1_000865

BRN 0611835

BSPBio_000785

C07047

CAS-3778-73-2

CCRIS 352

CHEBI:5864

CHEMBL1024

CID3690

Cyfos

D00343

D007069

DB01181

EINECS 223-237-3

HMS1570H07

HMS2090M12

HMS2093N07

Holoxan

Holoxan 1000

HSDB 7023

I06-0494

Ifex

IFEX (TN)

Ifosfamid

Ifosfamida

Ifosfamida [INN-Spanish]

ifosfamide

Ifosfamide (JAN/USP/INN)

Ifosfamide [USAN:INN:BAN:JAN]

Ifosfamide sterile

Ifosfamide Sterile

Ifosfamidum

Ifosfamidum [INN-Latin]

Ifosphamide

Ifsofamide

Iphosphamid

Iphosphamid(e)

Iphosphamide

I-phosphamide

I-Phosphamide

iso Endoxan

Iso Endoxan

iso-Endoxan

Isoendoxan

Iso-Endoxan

Isofosfamide

Isophosphamide

isosfamide

Isosfamide

LS-102

LS-99799

Mitoxana

Mitoxana, Ifex, Ifosfamide

MJF 9325

MJF-9325

MLS002154021

MolPort-003-666-704

N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid

N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid [German]

N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylen ephosphoric acid diamide

N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylene phosphoric acid ester diamide

N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid diamide

N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide

N-(2-Chloroethyl)-N-(3-(2-chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amine

N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide

N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

N,N-Bis(beta-chloroethyl)-amino-N',O-propylene-phosphoric acid ester diamide

Naxamide

NCGC00016639-01

NCGC00179435-01

NCI60_000233

NCI-C01638

NPFAPI-04

NSC 109,724

NSC 109724

NSC109,724

NSC-109,724

NSC109724

NSC-109724

Prestwick0_000833

Prestwick1_000833

Prestwick2_000833

Prestwick3_000833

S1302_Selleck

SMR001233348

SPBio_002706

STL058690

UNII-UM20QQM95Y

WLN: T6NPOTJ AM2G BO B2G

Z 4942

Z4942

Z-4942

Mechlorethamine

Approved, Investigational

Phase 2, Phase 3

51-75-2

4033

Synonyms:

.Beta.,.beta.'-Dichlorodiethyl-N-methylamine

1, 5-Dichloro-3-methyl-3-azapentane hydrochloride

126-85-2 (N-oxide)

2,2'-Dichlorodiethyl-methylamine

2,2'-Dichloro-N-me

2,2'-dichloro-N-methyldiethylamine

2,2'-dichloro-N-Methyldiethylamine

2,2'-Dichloro-N-methyldiethylamine

2-Chloro-N-(2-chloroethyl)-N-methylethanamine

302-70-5 (N-oxide, hydrochloride)

51-75-2

55-86-7 (HYDROCHLORIDE)

AC1L1H9H

Antimit

b,Beta'-dichlorodiethyl-N-methylamine

beta,beta'-Dichlorodiethyl-N-methylamine

beta,Beta'-dichlorodiethyl-N-methylamine

Bis(2-chloroethyl)methylamine

Bis(b-chloroethyl)methylamine

Bis(beta-chloroethyl) methylamine

Bis(beta-chloroethyl)methylamine

Bis(β-chloroethyl)methylamine

BRN 0605323

BSPBio_001947

C07115

C5H11Cl2N

Carolysine

Caryolysin

Caryolysine

CCRIS 447

CHEBI:28925

CHEMBL427

Chloramine (the nitrogen mustard)

Chlorethazine

Chlormethine

Chlormethine (INN)

Chlormethine [INN:BAN]

Chlormethinum [INN-Latin]

CID4033

Cloramin

Clormetina

Clormetina [INN-Spanish]

D07671

DB00888

Di(2-chloroethyl)methylamine

Dichlor amine

Dichloren

DivK1c_000759

EINECS 200-120-5

Embechine

Embichin

ENT-25294

HMS1920J15

HMS2091B04

HMS502F21

HN2

HN-2

HSDB 5083

Hydrochloride N-oxide, mechlorethamine

Hydrochloride, mechlorethamine

I14-8708

IBS-L0033631

IDI1_000759

KBio1_000759

KBio2_001369

KBio2_003937

KBio2_006505

KBio3_001447

KBioGR_001448

KBioSS_001369

LS-7559

MBA

Me chloroethamine

Mebichloramine

mechlorethamine

Mechlorethamine

Mechlorethamine hydrochloride

Mechlorethamine hydrochloride N oxide

Mechlorethamine hydrochloride N-oxide

Mechlorethamine N oxide

Mechlorethamine N-oxide

Mechlorethamine oxide

Mechlorethanamine

Mechloroethamine

Mecloretamina

Mecloretamina [Italian]

Merck brand OF mechlorethamine hydrochloride

Merck frosst brand OF mechlorethamine hydrochloride

Methylbis(2-chloroethyl)amine

Methylbis(b-chloroethyl)amine

Methylbis(beta-chloroethyl)amine

Methylbis(β-chloroethyl)amine

Methylchlorethamine

Methyldi(2-chloroethyl)amine

Mitomen

Mitoxine (*Hydrochloride*)

MolPort-001-785-592

Mustargen

Mustine

Mustine note

Mutagen

N,N-Bis(2-chloroethyl)methylamine

N,N-Bis(2-chloroethyl)-N-methylamine

N,N-Di(chloroethyl)methylamine

NCGC00091835-02

NCGC00091835-03

NCGC00091835-04

NCGC00091835-05

NCI60_041682

NINDS_000759

Nitol (*Hydrochloride*)

Nitrogen mustard

Nitrogen mustard (HN-2)

Nitrogen mustard N oxide

Nitrogen mustard N-oxide

Nitrogranulogen

Nitromin

N-Lost

N-Methyl lost

N-Methyl-2,2'-dichlorodiethylamine

N-methyl-bis(2-chloroethyl)amine

N-Methyl-bis(2-chloroethyl)amine

N-Methyl-bis(b-chloroethyl)amine

N-Methyl-bis(beta-chloroethyl)amine

N-Methyl-bis(β-chloroethyl)amine

N-Methyl-bis-chloraethylamin

N-Methyl-bis-chloraethylamin [German]

N-Methyl-lost

N-Methyl-lost [German]

N-Oxide, mechlorethamine hydrochloride

N-Oxide, nitrogen mustard

NSC 762

NSC762

NSC-762

SPBio_000496

Spectrum_000889

SPECTRUM1500375

Spectrum2_000448

Spectrum3_000484

Spectrum4_000924

Spectrum5_001702

Stickstofflost (*Hydrochloride*)

Stickstofflost (ebewe)

T 1024

T-1024

thyldiethylamine

TL 146

UNII-50D9XSG0VR

β,beta'-dichlorodiethyl-N-methylamine

β,β'-dichlorodiethyl-N-methylamine

Doxil

Approved June 1999

Phase 2, Phase 3

31703

Alkylating Agents

Phase 2, Phase 3

Anti-Bacterial Agents

Phase 2, Phase 3

Antibiotics, Antitubercular

Phase 2, Phase 3

Antineoplastic Agents, Alkylating

Phase 2, Phase 3

Isophosphamide mustard

Phase 2, Phase 3

Synonyms:

Ifosfamide mustard

Ifosforamide mustard

IPAM

Iphosphoramide mustard

Isophosphamide mustard

Isophosphoramide mustard

N,N'-di-(2-chloroethyl)phosphorodiamidic acid

NN'-Bis-(2-chloroethyl)phosphate

NN'-Bis-(2-chloroethyl)phosphoric acid

Palifosfamide-tris

zio-201Isophosphamide mustard

Topoisomerase Inhibitors

Phase 2, Phase 3

Crizotinib

Approved

Phase 2

877399-52-5

11626560 10366136 10366137 10366138 10366139 10366140 10366141

Protein Kinase Inhibitors

Phase 2,Phase 1

Ceritinib

Approved

Phase 1

1032900-25-6

Antibodies

Immunoglobulin G

Immunoglobulins

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery	Recruiting	NCT02180867	Phase 2, Phase 3	Doxorubicin Hydrochloride;Ifosfamide;Pazopanib Hydrochloride
2	Phase 1/2 Study of X-396, an Oral ALK Inhibitor, in Patients With ALK-positive Non-Small Cell Lung Cancer	Recruiting	NCT01625234	Phase 1, Phase 2	X-396 (ensartinib)
3	Phase 2 Study Assessing Efficacy and Safety of Crizotinib in Patients Harboring an Alteration on ALK, MET or ROS1	Active, not recruiting	NCT02034981	Phase 2	Crizotinib
4	CREATE: Cross-tumoral Phase 2 With Crizotinib	Active, not recruiting	NCT01524926	Phase 2	Crizotinib (PF-02341066)
5	Phase I Study of LDK378 in Pediatric, Malignancies With a Genetic Alteration in Anaplastic Lymphoma Kinase (ALK)	Recruiting	NCT01742286	Phase 1	LDK378
6	A Prospective Cohort Study of IgG4RD in China	Recruiting	NCT01670695
7	Low-dose Protocol for Computed Tomography-guided Lung Biopsy	Active, not recruiting	NCT02971176	Not Applicable
8	Treatment With Crizotinib Single Patient Expanded Access IND 134375	No longer available	NCT03085186		Crizotinib

Search NIH Clinical Center for Inflammatory Myofibroblastic Tumor

Sources

Genetic Tests for Inflammatory Myofibroblastic Tumor

Sources

Anatomical Context for Inflammatory Myofibroblastic Tumor

MalaCards organs/tissues related to Inflammatory Myofibroblastic Tumor:

⁴¹

Lung, Eye, Liver, Bone, Heart, Trachea, Spleen

Sources

Publications for Inflammatory Myofibroblastic Tumor

Articles related to Inflammatory Myofibroblastic Tumor:

(show top 50) (show all 603)

#	Title	Authors	Year
1	Inflammatory myofibroblastic tumor of heart in a 4-month-old infant. ( 29058974 )	Syed A.U....Al Najjar A.	2018
2	Inflammatory Myofibroblastic Tumor Driven by Novel<i>NUMA1-ALK</i>Fusion Responds to ALK Inhibition. ( 29439172 )	Rao N....Liebner D.A.	2018
3	The Clinical and Radiological Characteristics of Inflammatory Myofibroblastic Tumor Occurring at Unusual Sites. ( 29888269 )	Zeng X....Zhang J.	2018
4	Inflammatory myofibroblastic tumor of the esophagus presenting with hematemesis and melaena: a case report and review of literature. ( 29375843 )	Jayarajah U....Samarasekera D.N.	2018
5	An interesting case of inflammatory myofibroblastic tumor presenting as cholangiocarcinoma. ( 29705678 )	Karimi M....Shabestanipour G.	2018
6	Anaplastic lymphoma kinase-negative uterine inflammatory myofibroblastic tumor containing the ETV6-NTRK3 fusion gene: a case report. ( 29900760 )	Takahashi A....Hayashi Y.	2018
7	Inflammatory Myofibroblastic Tumor Associated With the Placenta: Short Tandem Repeat Genotyping Confirms Uterine Site of Origin. ( 29505427 )	Ladwig N.R....Umetsu S.E.	2018
8	Inflammatory myofibroblastic tumor of the orbit: A clinico-pathological study of 25 cases. ( 29755269 )	Strianese D....Mariniello G.	2018
9	Pulmonary inflammatory myofibroblastic tumor: a case report. ( 29649880 )	Tsuchiya T....Tanaka M.	2018
10	Inflammatory myofibroblastic tumor mimicking lymphoma on <sup>18</sup>F-FDG PET/CT. Report of a case and review of the literature. ( 29550850 )	Ma C....Su X.	2018
11	Neoadjuvant crizotinib in ALK-rearranged inflammatory myofibroblastic tumor of the urinary bladder: A case report. ( 29758320 )	Nagumo Y....Fujimoto H.	2018
12	An Unusual Case of Inflammatory Myofibroblastic Tumor of the Appendix Masquerading as Acute Appendicitis. ( 29896334 )	Bashir M.R....Al-Rikabi A.C.	2018
13	Uterine metastases originating from a pulmonary inflammatory myofibroblastic tumor. ( 29578184 )	Zhang J....Lou L.	2018
14	A dedifferentiated liposarcoma with inflammatory myofibroblastic tumor-like features. ( 29446522 )	Kai K....Aishima S.	2018
15	Inflammatory Myofibroblastic Tumor of the Mid Common Bile Duct Masquerading as Cholangiocarcinoma. ( 29453762 )	Verma R....Saha K.	2018
16	Cytodiagnosis of inflammatory myofibroblastic tumor: A report of three cases in infants. ( 29673102 )	Ghosh M....Chatterjee U.	2018
17	Inflammatory Myofibroblastic Tumor Arising in the Cul-De-Sac, Mimicking Ectopic Decidua. ( 29620583 )	Ioannidis I....Huang J.H.	2018
18	Inflammatory myofibroblastic tumor of the lung. ( 29490419 )	Khatri A....Meena N.	2018
19	Pulmonary Inflammatory Myofibroblastic Tumor in Children: A Case Report and Brief Review of Literature. ( 29535991 )	Camela F....Pession A.	2018
20	Inflammatory Myofibroblastic Tumor of the Tongue. Report of a Pediatric Case and Review of the Literature. ( 29336647 )	Caporalini C....Buccoliero A.M.	2018
21	Inflammatory myofibroblastic tumor of the prostate after transurethral resection of the prostate with negative expression of anaplastic lymphoma kinase: a case report. ( 29898011 )	Zeng J....Hu X.H.	2018
22	Plaque-like ALK-positive cutaneous inflammatory myofibroblastic tumor. ( 29564876 )	Diani M....Altomare G.	2018
23	Clinical and Histopathologic Correlates and Management Strategies for Inflammatory Myofibroblastic tumor of the lung. A case series and review of the literature. ( 29869302 )	Sagar A.E.S....Shannon V.R.	2018
24	A Case Report of Paraneoplastic Pemphigus Associated With Retroperitoneal Inflammatory Myofibroblastic Tumor. ( 28724275 )	Balighi K....Saeidi V.	2017
25	A case report of recurrent thyroid inflammatory myofibroblastic tumor and its metastasis in soft tissue. ( 29137037 )	Duan J....Wang Y.	2017
26	Relapsed and unresectable inflammatory myofibroblastic tumor responded to chemotherapy: A case report and review of the literature. ( 29046787 )	Maruyama Y....Koizumi T.	2017
27	Gastric inflammatory myofibroblastic tumor presenting as fever of unknown origin in a 9-year-old girl. ( 27748672 )	Jumanne S....McDERMOTT M.	2017
28	A novel fusion of HNRNPA1-ALK in inflammatory myofibroblastic tumor of urinary bladder. ( 28504207 )	Inamura K....Ishikawa Y.	2017
29	A case report of tracheal inflammatory myofibroblastic tumor in a 34-week pregnant woman misdiagnosed with asthma. ( 28816991 )	Li X....Xie M.	2017
30	Inflammatory myofibroblastic tumor of the lacrimal gland: case report of an exceptional location. ( 28824333 )	Boudhas A....Oukabli M.	2017
31	ALK-positive gastric inflammatory myofibroblastic tumor in an adult with familial adenomatous polyposis and diffuse fundic polyposis. ( 28923119 )	Fan J....Nie X.	2017
32	Inflammatory Myofibroblastic Tumor Diagnosed by Transbronchial Needle Aspiration. ( 28645432 )	VA!zquez I....Pijuan L.	2017
33	Inflammatory myofibroblastic tumor involving liver, gallbladder, pylorus &amp; duodenum: A rare case presentation. ( 28092784 )	Sinha L....Kumar M.	2017
34	Synchronous Inflammatory Myofibroblastic Tumor in Lung and Brain: A Case Report and Review of Literature. ( 28533999 )	Jehangir M....Mamoon N.	2017
35	Imaging findings of inflammatory myofibroblastic tumor from the greater omentum: One case report. ( 29019904 )	Liang W....Chen Z.	2017
36	Inflammatory Myofibroblastic Tumor of the Breast Mimicking Malignancy in an Elderly Male. ( 29026362 )	Siraj F....Sonam J.	2017
37	Inflammatory myofibroblastic tumor: An unusual hepatic tumor mimicking liver abscess. ( 28089176 )	Jin Y.W....Cheng N.S.	2017
38	Efficiency of Crizotinib on an ALK-Positive Inflammatory Myofibroblastic Tumor of the Central Nervous System: A Case Report. ( 28409069 )	Chennouf A....Wong P.	2017
39	Gastric inflammatory myofibroblastic tumor identified as ectopic pancreas and treated by endoscopic submucosal dissection. ( 28587772 )	Ning X....Xu M.	2017
40	Inflammatory myofibroblastic tumor of mandible: A rare case report and review of literature. ( 28479702 )	Korlepara R....Taneeru S.	2017
41	Targeting ALK With Crizotinib in Pediatric Anaplastic Large Cell Lymphoma and Inflammatory Myofibroblastic Tumor: A Children's Oncology Group Study. ( 28787259 )	MossAc Y.P....Weigel B.J.	2017
42	Inflammatory myofibroblastic tumor of kidney together with ipsilateral perinephric and periureteric fibrosis: A case report and literature review. ( 29245241 )	Sun Z....Jing C.	2017
43	Inflammatory myofibroblastic tumor of the lumbar spinal canal: A Case Report With Literature Review. ( 28658093 )	Wang S....Wang B.	2017
44	Central Nervous System Inflammatory Myofibroblastic Tumor Masquerading as Chronic Suppurative Otitis Media. ( 28904584 )	Singhal N....Tangri R.	2017
45	Dramatic response to alectinib in inflammatory myofibroblastic tumor with anaplastic lymphoma kinase fusion gene. ( 28977547 )	Saiki M....Nishio M.	2017
46	Rare Endobronchial Inflammatory Myofibroblastic Tumor in Pediatric Patient Detected on PET/CT Imaging. ( 28639954 )	Kara P.O....Kara T.	2017
47	Pulmonary inflammatory myofibroblastic tumor: report of 2 cases with radiologic-pathologic correlation. ( 28491163 )	Carvalho A....Pereira J.M.	2017
48	Successful Preservation of the Bladder in a Case of Inflammatory Myofibroblastic Tumor with the Diagnostic Efficacy of ALK/p80 Immunohistochemistry and FISH Analysis: Case Report and Review of the Literature. ( 28083479 )	Kato M....Sugimura Y.	2017
49	Pulmonary inflammatory Myofibroblastic tumor indistinguishable from tuberculosis: a case report in a five-year-old child with hemoptysis. ( 29216875 )	Zuo T....Chen B.	2017
50	Inflammatory Myofibroblastic Tumor of the Liver: Challenges in the Preoperative Diagnosis and Treatment. ( 29235003 )	Liu F....Li F.Y.	2017

Sources

Genes for Inflammatory Myofibroblastic Tumor

Genes related to Inflammatory Myofibroblastic Tumor (6 elite genes):

(show all 24)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ALK	ALK Receptor Tyrosine Kinase	Protein Coding	377.75	Gene fusion ⁵⁹ DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	RANBP2	RAN Binding Protein 2	Protein Coding	373.93	Gene fusion ⁵⁹ DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	TPM3	Tropomyosin 3	Protein Coding	373.86	Gene fusion ⁵⁹ DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	CARS	Cysteinyl-TRNA Synthetase	Protein Coding	362.64	Gene fusion ⁵⁹ DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	CLTC	Clathrin Heavy Chain	Protein Coding	356.95	Gene fusion ⁵⁹ DISEASES inferred ¹⁵
6	TPM4	Tropomyosin 4	Protein Coding	356.61	Gene fusion ⁵⁹ DISEASES inferred ¹⁵
7	RNF213	Ring Finger Protein 213	Protein Coding	26.91	GeneCards inferred via : Publications Summaries (show sections)
8	SEC31A	SEC31 Homolog A, COPII Coat Complex Component	Protein Coding	23.46	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
9	KIT	KIT Proto-Oncogene Receptor Tyrosine Kinase	Protein Coding	22.39	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
10	CR2	Complement C3d Receptor 2	Protein Coding	22	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
11	NPM1	Nucleophosmin 1	Protein Coding	21.51	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
12	CR1	Complement C3b/C4b Receptor 1 (Knops Blood Group)	Protein Coding	21.38	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
13	MDM2	MDM2 Proto-Oncogene	Protein Coding	20.81	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
14	TP53	Tumor Protein P53	Protein Coding	20.63	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
15	CCND1	Cyclin D1	Protein Coding	20.6	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
16	HNRNPA1	Heterogeneous Nuclear Ribonucleoprotein A1	Protein Coding	20.02	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
17	ACTC1	Actin, Alpha, Cardiac Muscle 1	Protein Coding	18.17	GeneCards inferred via : Publications (show sections)
18	VIM	Vimentin	Protein Coding	17.76	GeneCards inferred via : Publications (show sections)
19	DES	Desmin	Protein Coding	17.68	GeneCards inferred via : Publications (show sections)
20	S100B	S100 Calcium Binding Protein B	Protein Coding	17.59	GeneCards inferred via : Publications (show sections)
21	PPFIBP1	PPFIA Binding Protein 1	Protein Coding	12.67	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
22	EML4	Echinoderm Microtubule Associated Protein Like 4	Protein Coding	10.89	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
23	ACVRL1	Activin A Receptor Like Type 1	Protein Coding	7.48	GeneCards inferred via : Publications (show sections)
24	MKI67	Marker Of Proliferation Ki-67	Protein Coding	7.33	GeneCards inferred via : Publications (show sections)

Sources

Variations for Inflammatory Myofibroblastic Tumor

Sources

Expression for Inflammatory Myofibroblastic Tumor

Search GEO for disease gene expression data for Inflammatory Myofibroblastic Tumor.

Sources

Pathways for Inflammatory Myofibroblastic Tumor

Pathways related to Inflammatory Myofibroblastic Tumor according to GeneCards Suite gene sharing:

(show all 17)

#	Super pathways	Score	Top Affiliating Genes
1	Innate Immune System ⁶⁶ Show member pathways Immune System ⁶⁶ Neutrophil degranulation ⁶⁶	13.88	CCND1 CLTC CR1 KIT MDM2 RANBP2
2	Endometrial cancer ³⁷ Show member pathways Acute myeloid leukemia ³⁷ Binding of TCF/LEF-CTNNB1 to target gene promoters ⁶⁶ Chronic myeloid leukemia ³⁷ Colorectal cancer ³⁷ Pancreatic cancer ³⁷ Prostate cancer ³⁷ Signal transduction PTEN pathway ²² Thyroid cancer ³⁷	12.71	CCND1 KIT MDM2 TP53 TPM3
3	Pathways in cancer ³⁷	12.15	ALK CCND1 KIT MDM2 TP53 TPM3
4	Cytoskeletal Signaling ⁴	12.14	ACTC1 CLTC DES SEC31A VIM
5	Epstein-Barr virus infection ³⁷	12.08	CR2 MDM2 TP53 VIM
6	DNA Damage ⁴	12.02	CCND1 MDM2 NPM1 TP53 VIM
7	Dilated cardiomyopathy (DCM) ³⁷ Show member pathways Hypertrophic cardiomyopathy (HCM) ³⁷	11.94	ACTC1 DES TPM3 TPM4
8	Hematopoietic cell lineage ³⁷	11.72	CR1 CR2 KIT
9	Retinoblastoma (RB) in Cancer ¹	11.66	CCND1 MDM2 TP53
10	Cardiac muscle contraction ³⁷	11.58	ACTC1 TPM3 TPM4
11	Bladder cancer ³⁷ ¹	11.53	CCND1 MDM2 TP53
12	Copper homeostasis ¹	11.37	CCND1 MDM2 TP53
13	Proteolysis Putative SUMO-1 pathway ²² Show member pathways DNA damage Role of SUMO in p53 regulation ²²	11.34	MDM2 RANBP2 TP53
14	Aurora B signaling ¹ Show member pathways Aurora C signaling ¹ Signaling by Aurora kinases ¹	11.2	DES NPM1 VIM
15	DNA damage_ATM/ATR regulation of G1/S checkpoint ²²	11.14	CCND1 MDM2 TP53
16	Striated Muscle Contraction ¹ ⁶⁶	10.88	ACTC1 DES TPM3 TPM4 VIM
17	Sumoylation by RanBP2 regulates transcriptional repression ¹	10.57	MDM2 RANBP2

Sources

GO Terms for Inflammatory Myofibroblastic Tumor

Cellular components related to Inflammatory Myofibroblastic Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cytoskeleton	GO:0005856	9.95	ACTC1 CLTC DES NPM1 TPM3 TPM4
2	cytosol	GO:0005829	9.8	ACTC1 CARS CCND1 CLTC DES MDM2
3	focal adhesion	GO:0005925	9.65	ACTC1 CLTC NPM1 TPM4 VIM
4	cytoplasm	GO:0005737	9.58	ACTC1 ALK CARS CCND1 CLTC DES
5	actin filament	GO:0005884	9.54	ACTC1 TPM3 TPM4
6	muscle thin filament tropomyosin	GO:0005862	9.16	TPM3 TPM4
7	extracellular exosome	GO:0070062	10.02	ACTC1 ALK CLTC CR1 CR2 DES

Biological processes related to Inflammatory Myofibroblastic Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of cell proliferation	GO:0008284	9.88	CCND1 KIT MDM2 NPM1 S100B
2	negative regulation of apoptotic process	GO:0043066	9.73	ACTC1 ALK KIT MDM2 NPM1 TP53
3	positive regulation of gene expression	GO:0010628	9.72	ACTC1 KIT MDM2 TP53 VIM
4	viral process	GO:0016032	9.56	CR1 CR2 HNRNPA1 MDM2 NPM1 RANBP2
5	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	GO:0006977	9.54	MDM2 NPM1 TP53
6	response to magnesium ion	GO:0032026	9.46	CCND1 MDM2
7	complement receptor mediated signaling pathway	GO:0002430	9.43	CR1 CR2
8	mitotic G1 DNA damage checkpoint	GO:0031571	9.4	CCND1 TP53
9	cellular response to actinomycin D	GO:0072717	9.16	MDM2 TP53
10	muscle filament sliding	GO:0030049	9.02	ACTC1 DES TPM3 TPM4 VIM

Molecular functions related to Inflammatory Myofibroblastic Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protein homodimerization activity	GO:0042803	9.63	CARS CR2 KIT NPM1 S100B TPM4
2	identical protein binding	GO:0042802	9.5	ALK DES MDM2 S100B TP53 TPM4
3	disordered domain specific binding	GO:0097718	8.8	CLTC MDM2 TP53
4	protein binding	GO:0005515	10.19	ALK CARS CCND1 CLTC CR2 DES

Sources

Sources for Inflammatory Myofibroblastic Tumor

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia