MCID: INH017
MIFTS: 20

Inherited Congenital Spastic Tetraplegia

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Inherited Congenital Spastic Tetraplegia

MalaCards integrated aliases for Inherited Congenital Spastic Tetraplegia:

Name: Inherited Congenital Spastic Tetraplegia 59
Spastic Quadriplegic Cerebral Palsy 59 73
Inherited Congenital Spastic Quadriplegia 59
Quadriplegic Cerebral Palsy 73

Characteristics:

Orphanet epidemiological data:

59
inherited congenital spastic tetraplegia
Inheritance: Autosomal recessive; Prevalence: <1/1000000 (Worldwide); Age of onset: Infancy,Neonatal;

Classifications:

Orphanet: 59  
Rare neurological diseases


External Ids:

Orphanet 59 ORPHA210141
ICD10 via Orphanet 34 G11.4

Summaries for Inherited Congenital Spastic Tetraplegia

MalaCards based summary : Inherited Congenital Spastic Tetraplegia, also known as spastic quadriplegic cerebral palsy, is related to cerebral palsy and spastic quadriplegia. An important gene associated with Inherited Congenital Spastic Tetraplegia is ADD3 (Adducin 3). Affiliated tissues include bone, tongue and salivary gland.

Related Diseases for Inherited Congenital Spastic Tetraplegia

Diseases related to Inherited Congenital Spastic Tetraplegia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 cerebral palsy 30.5 ADD3 GAD1 KANK1
2 spastic quadriplegia 12.3
3 spastic paraplegia 50, autosomal recessive 11.4
4 spastic paraplegia 47, autosomal recessive 11.4
5 spastic paraplegia 52, autosomal recessive 11.4
6 hereditary spastic paraplegia 51 11.4
7 scoliosis 10.2

Graphical network of the top 20 diseases related to Inherited Congenital Spastic Tetraplegia:



Diseases related to Inherited Congenital Spastic Tetraplegia

Symptoms & Phenotypes for Inherited Congenital Spastic Tetraplegia

Drugs & Therapeutics for Inherited Congenital Spastic Tetraplegia

Search Clinical Trials , NIH Clinical Center for Inherited Congenital Spastic Tetraplegia

Genetic Tests for Inherited Congenital Spastic Tetraplegia

Anatomical Context for Inherited Congenital Spastic Tetraplegia

MalaCards organs/tissues related to Inherited Congenital Spastic Tetraplegia:

41
Bone, Tongue, Salivary Gland

Publications for Inherited Congenital Spastic Tetraplegia

Articles related to Inherited Congenital Spastic Tetraplegia:

(show all 25)
# Title Authors Year
1
ASSESSMENT OF NUTRITIONAL STATUS OF CHILDREN AND ADOLESCENTS WITH SPASTIC QUADRIPLEGIC CEREBRAL PALSY. ( 28723982 )
2017
2
Single-Trial Analysis of Inter-Beat Interval Perturbations Accompanying Single-Switch Scanning: Case Series of Three Children With Severe Spastic Quadriplegic Cerebral Palsy. ( 26068545 )
2016
3
Treatment of os odontoideum in a patient with spastic quadriplegic cerebral palsy. ( 25913747 )
2015
4
Health benefits of seated speed, resistance, and power training for an individual with spastic quadriplegic cerebral palsy: A case report. ( 26410068 )
2015
5
Autonomic responses to correct outcomes and interaction errors during single-switch scanning among children with severe spastic quadriplegic cerebral palsy. ( 24607065 )
2014
6
Disruption of Basal lamina components in neuromotor synapses of children with spastic quadriplegic cerebral palsy. ( 23976945 )
2013
7
Surgical Treatment of Scoliosis in Non-Ambulatory Spastic Quadriplegic Cerebral Palsy Patients: A Matched Cohort Comparison of Unit Rod Technique and All-Pedicle Screw Constructs. ( 27927398 )
2013
8
Client-centred development of an infrared thermal access switch for a young adult with severe spastic quadriplegic cerebral palsy. ( 20569118 )
2011
9
Lower extremity orthoses in children with spastic quadriplegic cerebral palsy: implications for nurses, parents, and caregivers. ( 21597341 )
2011
10
Determinants of ambulation in children with spastic quadriplegic cerebral palsy: a population-based study. ( 19794101 )
2010
11
A multiple camera tongue switch for a child with severe spastic quadriplegic cerebral palsy. ( 19941441 )
2010
12
Decreased fracture incidence after 1 year of pamidronate treatment in children with spastic quadriplegic cerebral palsy. ( 20573180 )
2010
13
Relationships between developmental profiles and ambulatory ability in A follow-up study of preschool children with spastic quadriplegic cerebral palsy. ( 20979703 )
2010
14
TREATMENT OF PARALYTIC HIP DISLOCATION AMONG SPASTIC QUADRIPLEGIC CEREBRAL PALSY PATIENTS BY MEANS OF FEMORAL AND PELVIC OSTEOTOMY, WITHOUT OPENING THE JOINT CAPSULE (CAPSULOPLASTY). ( 27022539 )
2010
15
Follow-up of developmental profiles in children with spastic quadriplegic cerebral palsy. ( 20035642 )
2009
16
Comorbidities and clinical determinants of outcome in children with spastic quadriplegic cerebral palsy. ( 18248493 )
2008
17
Botulinum toxin type a injections to salivary glands: combination with single event multilevel chemoneurolysis in 2 children with severe spastic quadriplegic cerebral palsy. ( 16401453 )
2006
18
Awake upper airway obstruction in children with spastic quadriplegic cerebral palsy. ( 16487389 )
2006
19
Reduced body protein in children with spastic quadriplegic cerebral palsy. ( 16522908 )
2006
20
Comparison of the ratio of upper to lower chest wall in children with spastic quadriplegic cerebral palsy and normally developed children. ( 16642554 )
2006
21
Pamidronate treatment and posttreatment bone density in children with spastic quadriplegic cerebral palsy. ( 16785077 )
2006
22
Effect of selective dorsal rhizotomy on need for orthopedic surgery for spastic quadriplegic cerebral palsy: long-term outcome analysis in relation to age. ( 16206973 )
2004
23
Motor benefit from levodopa in spastic quadriplegic cerebral palsy. ( 10805341 )
2000
24
Energy expenditure and body composition in children with spastic quadriplegic cerebral palsy. ( 8969729 )
1996
25
Body composition in children with spastic quadriplegic cerebral palsy. ( 7752019 )
1995

Variations for Inherited Congenital Spastic Tetraplegia

Expression for Inherited Congenital Spastic Tetraplegia

Search GEO for disease gene expression data for Inherited Congenital Spastic Tetraplegia.

Pathways for Inherited Congenital Spastic Tetraplegia

GO Terms for Inherited Congenital Spastic Tetraplegia

Cellular components related to Inherited Congenital Spastic Tetraplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell cortex GO:0005938 8.62 ADD3 GAD1

Sources for Inherited Congenital Spastic Tetraplegia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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