MCID: INH003
MIFTS: 15

Inhibited Female Orgasm

Categories: Reproductive diseases

Aliases & Classifications for Inhibited Female Orgasm

MalaCards integrated aliases for Inhibited Female Orgasm:

Name: Inhibited Female Orgasm 12 15
Female Orgasmic Disorder 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:7518
ICD10 33 F52.31
ICD9CM 35 302.73
NCIt 50 C34958
SNOMED-CT 68 191794003 60103007
UMLS 73 C0033948

Summaries for Inhibited Female Orgasm

MalaCards based summary : Inhibited Female Orgasm, also known as female orgasmic disorder, is related to hypoactive sexual desire disorder. An important gene associated with Inhibited Female Orgasm is PROS1 (Protein S). The drugs Dopamine and Bupropion have been mentioned in the context of this disorder.

Related Diseases for Inhibited Female Orgasm

Diseases related to Inhibited Female Orgasm via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 hypoactive sexual desire disorder 9.9

Symptoms & Phenotypes for Inhibited Female Orgasm

Drugs & Therapeutics for Inhibited Female Orgasm

Drugs for Inhibited Female Orgasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 2, Phase 3 51-61-6, 62-31-7 681
2
Bupropion Approved Phase 2, Phase 3 34841-39-9, 34911-55-2 444
3 Neurotransmitter Agents Phase 2, Phase 3
4 Neurotransmitter Uptake Inhibitors Phase 2, Phase 3
5 Cytochrome P-450 CYP2D6 Inhibitors Phase 2, Phase 3
6 Cytochrome P-450 Enzyme Inhibitors Phase 2, Phase 3
7 Dopamine Agents Phase 2, Phase 3
8 Dopamine Uptake Inhibitors Phase 2, Phase 3
9 Antidepressive Agents Phase 2, Phase 3
10 Antidepressive Agents, Second-Generation Phase 2, Phase 3
11 Psychotropic Drugs Phase 2, Phase 3
12
Sertraline Approved Phase 2 79617-96-2 68617
13
Testosterone undecanoate Approved, Investigational Phase 2 5949-44-0
14
Paroxetine Approved, Investigational Phase 2 61869-08-7 43815
15
Fluoxetine Approved, Vet_approved Phase 2 54910-89-3 3386
16
Testosterone Approved, Investigational Phase 2 58-22-0 6013
17
Methyltestosterone Approved Phase 2 58-18-4 6010
18
Testosterone enanthate Approved Phase 2 315-37-7 9416
19 Anabolic Agents Phase 2
20 Testosterone 17 beta-cypionate Phase 2
21 Androgens Phase 2
22 Hormone Antagonists Phase 2
23 Hormones Phase 2
24 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
25 Antineoplastic Agents, Hormonal Phase 2
26 Ginkgo Nutraceutical Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Female Orgasmic Disorder (FOD) and Wellbutrin XL Completed NCT00248209 Phase 2, Phase 3 Wellbutrin XL
2 Efficacy and Safety of TBS-2 Testosterone Gel in Women With Acquired Female Orgasmic Disorder Completed NCT01607658 Phase 2 Placebo;Low dose TBS-2;Medium dose TBS-2;High dose TBS-2
3 Ginkgo Biloba: Antidepressant-Induced Sexual Dysfunction Completed NCT00034021 Phase 2 Ginkgo Biloba
4 Platelet Rich Plasma (PRP) Peri-urethral and Clitoral Injections for the Treatment of Female Orgasmic Disorder Recruiting NCT03189238 Phase 2
5 Effects of Early Abuse on Adult Intimate Relationships Completed NCT01803802 Not Applicable

Search NIH Clinical Center for Inhibited Female Orgasm

Genetic Tests for Inhibited Female Orgasm

Anatomical Context for Inhibited Female Orgasm

Publications for Inhibited Female Orgasm

Articles related to Inhibited Female Orgasm:

# Title Authors Year
1
Validation of the Female Sexual Function Index (FSFI) in women with female orgasmic disorder and in women with hypoactive sexual desire disorder. ( 12519665 )
2003
2
Inhibited female orgasm resulting from psychotropic drugs. A five-year, updated, clinical review. ( 2405155 )
1990
3
Antidepressants and inhibited female orgasm: a literature review. ( 3066913 )
1988
4
Psychiatric drugs and inhibited female orgasm. ( 2902230 )
1988
5
Inhibited female orgasm as a side effect of alprazolam. ( 2863987 )
1985
6
Inhibited female orgasm resulting from psychotropic drugs. A clinical review. ( 6887155 )
1983
7
MAOI-induced inhibited female orgasm. ( 6614264 )
1983

Variations for Inhibited Female Orgasm

Expression for Inhibited Female Orgasm

Search GEO for disease gene expression data for Inhibited Female Orgasm.

Pathways for Inhibited Female Orgasm

GO Terms for Inhibited Female Orgasm

Sources for Inhibited Female Orgasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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