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MCID: INT007
MIFTS: 47

Intermediate Coronary Syndrome

Categories: Cardiovascular diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Intermediate Coronary Syndrome

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MalaCards integrated aliases for Intermediate Coronary Syndrome:

Name: Intermediate Coronary Syndrome 12 15
Angina, Unstable 44 73
Unstable Angina 12 15
Myocardial Preinfarction Syndrome 73
Anginal Chest Pain at Rest 12
Impending Infarction 12
Preinfarction Angina 12
Worsening Angina 12
Angina at Rest 12

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:8805
ICD10 33 I20.0
ICD9CM 35 411.1
MeSH 44 D000789
NCIt 50 C66911
Sources

Summaries for Intermediate Coronary Syndrome

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MalaCards based summary : Intermediate Coronary Syndrome, also known as angina, unstable, is related to coronary heart disease 1 and ischemia, and has symptoms including angina pectoris An important gene associated with Intermediate Coronary Syndrome is UBAP1 (Ubiquitin Associated Protein 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Selenium Micronutrient Network. The drugs Clopidogrel and Ticagrelor have been mentioned in the context of this disorder. Affiliated tissues include lung, bone and brain, and related phenotypes are cardiovascular system and hematopoietic system

Sources

Related Diseases for Intermediate Coronary Syndrome

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Diseases related to Intermediate Coronary Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 194)
# Related Disease Score Top Affiliating Genes
1 coronary heart disease 1 31.8 ACE CRP IL6 PLAT SELP VWF
2 ischemia 30.7 ACE MB PLAT SELP
3 subendocardial myocardial infarction 30.1 MB SERPINC1
4 ischemic heart disease 30.1 ACE CRP IL6
5 carotid stenosis 30.0 ACE CRP SELP
6 gas gangrene 30.0 MB PIK3C2A TNNI3
7 coronary thrombosis 30.0 F3 P2RY12 PLAT SERPINC1 VWF
8 thrombosis 30.0 F3 P2RY12 PLAT SELP SERPINC1 VWF
9 maturity-onset diabetes of the young, type 1 30.0 ACE CRP IL6
10 essential thrombocythemia 30.0 F3 ITGA2B SELP VWF
11 systolic heart failure 29.9 ACE CRP IL6
12 coronary artery anomaly 29.7 ACE CRP MB PIK3C2A PLAT PLG
13 intermittent claudication 29.6 ACE CRP IL6 SELP SERPINC1 VWF
14 thrombocytosis 29.5 CRP F3 IL6 SELP SERPINC1
15 antiphospholipid syndrome 29.5 F3 PLAT SELP SERPINC1 VWF
16 coronary stenosis 29.2 ACE CRP IL6 PIK3C2A TNNI3 VWF
17 heart disease 28.9 ACE CRP F3 IL6 PIK3C2A PLAT
18 peripheral vascular disease 28.8 ACE CRP F3 IL6 PLAT SELP
19 angina pectoris 28.8 ACE CRP IL6 PIK3C2A PLAT SERPINC1
20 arteries, anomalies of 28.5 ACE CRP F3 IL6 ITGA2B MB
21 vascular disease 28.4 ACE CRP F3 IL6 PLAT PLG
22 acute myocardial infarction 28.1 ACE CRP F3 ITGA2B MB PIK3C2A
23 myocardial infarction 27.4 ACE CRP F3 IL6 ITGA2B MB
24 chlamydia 10.3
25 rheumatic myocarditis 10.2 CRP TNNI3
26 anterolateral myocardial infarction 10.2 ACE PLAT
27 aspirin allergy 10.2 ITGA2B SERPINC1
28 renal artery obstruction 10.2 ACE SERPINC1
29 fournier gangrene 10.2 F3 SERPINC1
30 heparin-induced thrombocytopenia 10.2 F3 SERPINC1
31 tick paralysis 10.2 PIK3C2A TNNI3
32 burns 10.2 CRP SERPINC1
33 diabetes mellitus 10.2
34 fibrinolytic defect 10.2 PLAT SERPINC1
35 japanese spotted fever 10.2 CRP SERPINC1
36 sagittal sinus thrombosis 10.2 F3 SERPINC1
37 virus associated hemophagocytic syndrome 10.2 MB PIK3C2A
38 interstitial myocarditis 10.2 MB PIK3C2A
39 argentine hemorrhagic fever 10.2 PLAT SERPINC1
40 thrombasthenia 10.2 F3 ITGA2B SELP
41 peripheral vertigo 10.2 CRP F3 SERPINC1
42 coronary restenosis 10.1 ACE SERPINC1
43 fiedler's myocarditis 10.1 ACE PIK3C2A
44 generalized atherosclerosis 10.1 ACE CRP SELP
45 coronary artery vasospasm 10.1
46 cold agglutinin disease 10.1 CRP IL6
47 cardiac rupture 10.1 CRP PLAT
48 pericardium disease 10.1 CRP PIK3C2A TNNI3
49 chlamydia pneumonia 10.1
50 myocardial stunning 10.1

Comorbidity relations with Intermediate Coronary Syndrome via Phenotypic Disease Network (PDN): (show top 50) (show all 104)


Acquired Thrombocytopenia Active Peptic Ulcer Disease
Acute Cystitis Acute Kidney Failure
Acute Myocardial Infarction Acute Stress Disorder
Allergic Urticaria Angina Pectoris
Anthracosis Anxiety
Aortic Aneurysm Aortic Atherosclerosis
Aortic Valve Disease 1 Aortic Valve Disease 2
Asbestosis Atrioventricular Block
Atrophic Gastritis Basilar Artery Insufficiency
Benign Essential Hypertension Benign Hypertensive Renal Disease
Bleeding Disorder, Platelet-Type, 11 Bronchitis
Cardiac Arrest Cardiac Arrhythmia
Cardiogenic Shock Cerebrovascular Disease
Chronic Intestinal Vascular Insufficiency Chronic Kidney Failure
Chronic Myocardial Ischemia Constrictive Pericarditis
Coronary Artery Aneurysm Deficiency Anemia
Diabetic Polyneuropathy Diaphragm Disease
Dressler's Syndrome Duodenitis
Dyskinesia of Esophagus Dysthymic Disorder
Esophagitis Familial Atrial Fibrillation
First-Degree Atrioventricular Block Gallbladder Disease
Gastroesophageal Reflux Generalized Atherosclerosis
Gout Heart Disease
Hemopericardium Hyperlipoproteinemia, Type I
Hyperlipoproteinemia, Type Iv Hyperlipoproteinemia, Type V

Graphical network of the top 20 diseases related to Intermediate Coronary Syndrome:



Diseases related to Intermediate Coronary Syndrome
Sources

Symptoms & Phenotypes for Intermediate Coronary Syndrome

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UMLS symptoms related to Intermediate Coronary Syndrome:


angina pectoris

MGI Mouse Phenotypes related to Intermediate Coronary Syndrome:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.22 ACE CRP F3 IL6 ITGA2B MB
2 hematopoietic system MP:0005397 10.15 ACE F3 IL6 ITGA2B MB P2RY12
3 homeostasis/metabolism MP:0005376 10.13 ACE CRP F3 IL6 ITGA2B MB
4 immune system MP:0005387 10 ACE CRP F3 IL6 ITGA2B PIK3C2A
5 mortality/aging MP:0010768 9.9 ACE F3 IL6 MB PIK3C2A PLAT
6 renal/urinary system MP:0005367 9.43 ACE IL6 PIK3C2A PLG SELP SERPINC1
7 respiratory system MP:0005388 9.17 F3 IL6 MB PLAT PLG SELP
Sources

Drugs & Therapeutics for Intermediate Coronary Syndrome

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Drugs for Intermediate Coronary Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 460)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clopidogrel Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 113665-84-2, 120202-66-6 60606
2
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 274693-27-5 9871419
3
Bivalirudin Approved, Investigational Phase 4,Phase 3 128270-60-0 16129704
4
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 772 46507594
5
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-78-2 2244
6
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
7
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 33069-62-4 36314
8
Pravastatin Approved Phase 4,Phase 3,Not Applicable 81093-37-0 54687
9
Rivaroxaban Approved Phase 4,Phase 3,Phase 2 366789-02-8
10
Citalopram Approved Phase 4 59729-33-8 2771
11
Carvedilol Approved, Investigational Phase 4,Phase 3,Not Applicable 72956-09-3 2585
12
Colchicine Approved Phase 4,Phase 3,Phase 2 64-86-8 6167 2833
13
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 53123-88-9 46835353 6436030 5284616
14
Everolimus Approved Phase 4,Phase 3,Phase 2,Not Applicable 159351-69-6 6442177
15
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 22916-47-8 4189
16
Etanercept Approved, Investigational Phase 4 185243-69-0
17
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Not Applicable 58-93-5 3639
18
Fosinopril Approved Phase 4 98048-97-6 55891
19
Hydroxocobalamin Approved Phase 4,Phase 3,Not Applicable 13422-51-0 11953898 44475014
20
leucovorin Approved Phase 4,Phase 3,Not Applicable 58-05-9 6006 143
21
Ramipril Approved Phase 4,Not Applicable 87333-19-5 5362129
22 Nutmeg Approved Phase 4,Phase 3,Phase 2,Not Applicable
23
Nitroglycerin Approved, Investigational Phase 4,Phase 3,Not Applicable 55-63-0 4510
24
Febuxostat Approved Phase 4,Phase 3,Not Applicable 144060-53-7 134018
25 tannic acid Approved Phase 4,Phase 3,Not Applicable
26
Benzocaine Approved, Investigational Phase 4,Phase 3,Not Applicable 94-09-7, 1994-09-7 2337
27
Warfarin Approved Phase 4,Phase 3 81-81-2 6691 54678486
28
Fondaparinux Approved, Investigational Phase 4,Phase 3 104993-28-4
29
Pioglitazone Approved, Investigational Phase 4,Phase 3 111025-46-8 4829
30
Angiotensin II Approved, Investigational Phase 4,Phase 3,Not Applicable 11128-99-7, 68521-88-0, 4474-91-3 172198 65143
31
Saxagliptin Approved Phase 4,Phase 3 361442-04-8 11243969
32
Lornoxicam Approved, Investigational Phase 4 70374-39-9 5282204
33
Piroxicam Approved, Investigational Phase 4 36322-90-4 54676228 5280452
34
Dopamine Approved Phase 4,Phase 3 51-61-6, 62-31-7 681
35
Bupropion Approved Phase 4,Phase 3 34841-39-9, 34911-55-2 444
36
Cobalt Approved, Experimental Phase 4,Phase 2,Phase 3,Not Applicable 7440-48-4 104729
37
Chromium Approved Phase 4,Phase 2,Phase 3,Not Applicable 7440-47-3 27668
38
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
39
Fenofibrate Approved Phase 4,Phase 3 49562-28-9 3339
40
Bezafibrate Approved, Investigational Phase 4 41859-67-0 39042
41
Ezetimibe Approved Phase 4,Phase 3 163222-33-1 150311
42
Fluvastatin Approved Phase 4,Phase 3 93957-54-1 1548972
43
Simvastatin Approved Phase 4,Phase 3,Phase 2,Not Applicable 79902-63-9 54454
44
AT-101 Approved, Investigational Phase 4 90141-22-3, 652-67-5 12597
45
Isosorbide Dinitrate Approved, Investigational Phase 4 87-33-2 6883
46
Bisoprolol Approved Phase 4,Not Applicable 66722-44-9 2405
47
Nitric Oxide Approved Phase 4,Phase 1,Not Applicable 10102-43-9 145068
48
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
49
Candesartan cilexetil Approved Phase 4 145040-37-5 2540
50
Glipizide Approved, Investigational Phase 4 29094-61-9 3478

Interventional clinical trials:

(show top 50) (show all 655)
# Name Status NCT ID Phase Drugs
1 Efficacy and Safety of Salvianolate Injection in Elderly Patients With Unstable Angina Pectoris Unknown status NCT03037047 Phase 4 0.9% Sodium Chloride Injection;salvianolate injection
2 Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome Unknown status NCT01372839 Phase 4 Atorvastatin;Statin
3 Downstream Versus Upstream Strategy for the Administration of P2Y12 Receptor Blockers Unknown status NCT02618837 Phase 4
4 Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome Unknown status NCT02037412 Phase 4 Ticagrelor;Clopidogrel
5 Small Coronary Artery Treated by TAXUS Liberté Registry in Japan Unknown status NCT00955214 Phase 4
6 Coronary Angioplasty in Octogenarians With Emergent Coronary Syndromes Unknown status NCT02126202 Phase 4
7 Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study Unknown status NCT00688922 Phase 4 Pravastatin
8 Atrial Fibrillation and Ischemic Events With Rivaroxaban in Patients With Stable Coronary Artery Disease Study Unknown status NCT02642419 Phase 4 Rivaroxaban and single antiplatelet drug (aspirin, clopidogrel or prasugrel);Rivaroxaban
9 A Trial to Evaluate Efficacy of Heart-protecting Musk Pill Unknown status NCT01897805 Phase 4 Heart-protecting Musk Pill;Placebo
10 Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance Image Unknown status NCT01769482 Phase 4 Udenafil;placebo
11 Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome Unknown status NCT00815100 Phase 4 Ivabradine;Placebo
12 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
13 DECARD: Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome Unknown status NCT00140257 Phase 4 Escitalopram
14 Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Differences Between the Loading Dose of Prasugrel and Ticagrelor . Unknown status NCT02032303 Phase 4 Ticagrelor loading;Prasugrel loading
15 Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel Unknown status NCT02032290 Phase 4 ticagrelor loading;Clopidogrel loading
16 Ischemia In Hemodialysed Patients: Ivabradine Versus Carvedilol Unknown status NCT01425164 Phase 4 Ivabradine;Carvedilol
17 The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke Trial Unknown status NCT00724724 Phase 4 Butylphthalide Soft Capsules;Aspirin
18 Colchicine for Acute Coronary Syndromes Unknown status NCT01906749 Phase 4 Colchicine;Placebo
19 Vitamin D and Inflammatory Cytokine Levels After Acute Myocardial Infraction (MI) Unknown status NCT01115842 Phase 4 Vitamin D
20 The Beneficial Role of Percutaneous Coronary Intervention Over Optimal Medical Therapy in Elderly Patients With Coronary Artery Disease Unknown status NCT01508663 Phase 4 ARB, CCB, ACE-inhibitor, statin, Nitrate, Antiplate etc.
21 Etanercept Treating Patient With Acute ST Segment Elevated Myocardial Infarction Unknown status NCT01372930 Phase 4 Etanercept;saline
22 Revascularization in Heart Failure Trial – REHEAT 2 Unknown status NCT00388245 Phase 4
23 Benidipine and Hydrochlorothiazide in Fosinopril Treated Chronic Kidney Disease Patients With Hypertension Unknown status NCT02646397 Phase 4 Fosinopril;Benidipine;Hydrochlorothiazide
24 HOPE-2 Study (Heart Outcomes Prevention Evaluation-2 Study) Unknown status NCT00106886 Phase 4 Folic acid, vitamin B6 and B12 or placebo
25 Effects of Levothyroxine Supplementation in Patients With Systolic Heart Failure and Subclinical Hypothyroidism Unknown status NCT02316743 Phase 4 Levothyroxine supplementation
26 The Effect of Tongguan Capsule for MicroRNA Profiles in Coronary Heart Disease Patients Unknown status NCT02850627 Phase 4 Tongguan capsule;placebo capsule
27 Sodium Tanshinone IIA Sulfonate in Left Ventricular Remodeling Secondary to Acute Myocardial Infarction Unknown status NCT02524964 Phase 4 sodium tanshinone IIA sulfonate
28 Danhong Injection in the Treatment of Unstable Angina Pectoris Completed NCT02007187 Phase 4 Danhong injection;Placebo
29 Comparison of Administration Strategies of Ticagrelor in Patients With Unstable Angina Pectoris, a Pharmacokinetic / Pharmacodynamic Study Completed NCT02612116 Phase 4 Pulverized ticagrelor sublingually;Pulverized ticagrelor orally;Integral ticagrelor
30 Diagnosis and Treatment of Acute Coronary Syndrome in the ED & the Impact of Rapid Bedside cTnl on Outcome. Completed NCT00276432 Phase 4
31 Beta-cell Function in Glucose Abnormalities and Acute Myocardial Infarction Completed NCT00627744 Phase 4 Sitagliptin
32 Fondaparinux Trial With Unfractionated Heparin (UFH) During Revascularization in Acute Coronary Syndromes (ACS) Completed NCT00790907 Phase 4 fondaparinux background and standard dose UFH;Fondaparinux background and low dose heparin;Open label fondaparinux
33 Protective Effect of EPA on Cardiovascular Events Completed NCT00231738 Phase 4 Eicosapentaenoic acid ethyl ester(EPADEL Capsule 300 TM)
34 Conservative Non-Invasive Versus Routine Invasive Management in Coronary Artery Bypass Surgery Patients With Non ST Elevation Elevation Acute Coronary Syndrome Completed NCT01895751 Phase 4
35 Aspirin Non-responsiveness and Clopidogrel Endpoint Trial. Completed NCT00222261 Phase 4 aspirin;clopidogrel
36 The Effect of Pioglitazone on Neointima Volume and Characteristics Observed by Optical Coherence Tomography (OCT) Completed NCT01331967 Phase 4 Pioglitazone
37 A Randomized Evaluation of First-dollar Coverage for Post-MI Secondary Preventive Therapies Completed NCT00566774 Phase 4
38 Does Saxagliptin Reduce the Risk of Cardiovascular Events When Used Alone or Added to Other Diabetes Medications Completed NCT01107886 Phase 4 Saxagliptin;Placebo
39 Efficacy and Safety of Lornoxicam in Patients With Acute Coronary Syndrome Completed NCT00997750 Phase 4 Lornoxicam
40 Bupropion for Hospitalized Smokers With Acute Cardiovascular Disease Completed NCT00181818 Phase 4 bupropion SR (sustained-release)
41 Multiple Interventions Related to Dialysis Procedures in Order to Reduce Cardiovascular Morbidity and Mortality in HD Patients(EGESTUDY) Completed NCT00295191 Phase 4
42 Resistance to Aspirin and/or Clopidogrel Among Patients With PAD. Completed NCT00262561 Phase 4 Aspirin
43 Comparison of Post-dilution On-line Hemodiafiltration and Hemodialysis Completed NCT00411177 Phase 4
44 Prospective, Single-arm, Multicenter Study for Evaluation the Safety and Effectiveness of the ALEX Stent in a Real-world Setting of Percutaneous Coronary Interventions in Patients With Coronary Heart Disease Completed NCT01637012 Phase 4
45 Acarbose Cardiovascular Evaluation Trial Completed NCT00829660 Phase 4 Acarbose;Matching Placebo
46 The Effect of Atorvastatin and Pioglitazone on Carotid Atherosclerosis With the Use of Positron Emission Tomography-computed Tomography (PET-CT) Completed NCT01341730 Phase 4 Atorvastatin 20mg;Atorvastatin 20 mg + Pioglitazone 30 mg
47 DANish Multicenter STENT Trial Completed NCT00139802 Phase 4
48 Evaluation of Coronary Artery Plaque Volume Progression/Regression and Safety of Alirocumab in Japanese Patients Hospitalized for Acute Coronary Syndrome With Hypercholesterolemia Completed NCT02984982 Phase 4 alirocumab SAR236553;atorvastatin;rosuvastatin;fenofibrate;bezafibrate;ezetimibe;antiplatelets;anticoagulants
49 Intensive Statin Treatment in Chinese Coronary Artery Disease Patients Undergoing PCI Completed NCT01293097 Phase 4 Atorvastatin;Statin
50 Effect of Pioglitazone on Insulin Resistance, Atherosclerosis Progression and Clinical Course of Coronary Heart Disease Completed NCT03011775 Phase 4 Pioglitazone 15 mg Tablet;Isosorbide Dinitrate 10Mg Tablet;Acetylsalicylic Acid 75Mg Tablet;Bisoprolol Fumarate 2.5 MG Oral Tablet;Rosuvastatin Calcium 20 MG Oral Tablet;ramipril 5 MG

Search NIH Clinical Center for Intermediate Coronary Syndrome

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: angina, unstable

Sources

Genetic Tests for Intermediate Coronary Syndrome

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Anatomical Context for Intermediate Coronary Syndrome

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MalaCards organs/tissues related to Intermediate Coronary Syndrome:

41
Lung, Bone, Brain, Kidney, Heart, Thyroid, Bone Marrow
Sources

Publications for Intermediate Coronary Syndrome

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Articles related to Intermediate Coronary Syndrome:

(show all 24)
# Title Authors Year
1
Management of intermediate coronary syndrome: role of conservative treatment, glycoprotein IIb/IIIa receptor inhibitors, and direct intervention. ( 11076127 )
2000
2
Comparison of the histopathology of culprit lesions in chronic stable angina, unstable angina, and myocardial infarction. ( 9220182 )
1997
3
Unstable angina pectoris. Platelet behavior and prognosis in progressive angina and intermediate coronary syndrome. ( 2136815 )
1990
4
A review of nitrate therapy in stable angina, variant angina, unstable angina and myocardial infarction. ( 3913176 )
1985
5
Atenolol, heparin and the intermediate coronary syndrome. ( 6113419 )
1981
6
The intermediate coronary syndrome. ( 6971456 )
1981
7
Trial of heparin versus atenolol in prevention of myocardial infarction in intermediate coronary syndrome. ( 6112564 )
1981
8
Pathophysiologic significance of S-T and T wave abnormalities in patients with the intermediate coronary syndrome. ( 299974 )
1977
9
Long-term follow-up in patients receiving emergency revascularization for intermediate coronary syndrome. ( 4600203 )
1974
10
SURGICAL MANAGEMENT OF THE INTERMEDIATE CORONARY SYNDROME. ( 15215960 )
1974
11
Editorial: Intermediate coronary syndrome. ( 4148257 )
1973
12
The natural history of intermediate coronary syndrome. ( 4721961 )
1973
13
Bradycardia in intermediate coronary syndrome. ( 4723578 )
1973
14
Letter: Intermediate coronary syndrome. ( 4752330 )
1973
15
The intermediate coronary syndrome: clinical, angiographic and therapeutic aspects. ( 4144755 )
1973
16
Early diagnosis of acute myocardial infarction with special reference to the diagnosis of the intermediate coronary syndrome. A clinical study. ( 4586014 )
1972
17
Recognition and management of the intermediate coronary syndrome. ( 6021604 )
1967
18
Diagnosis and management of the intermediate coronary syndrome. A clinical study of 400 cases of the syndrome. ( 5932254 )
1966
19
THE INTERMEDIATE CORONARY SYNDROME. ( 14061336 )
1963
20
"Minor" infarction. (The so-called "intermediate coronary syndrome"). ( 14498476 )
1962
21
Intermediate coronary syndrome. ( 13779654 )
1961
22
Electrocardiographic changes in the intermediate coronary syndrome. II. Location of lesions. ( 13286446 )
1956
23
The intermediate coronary syndrome. ( 13226558 )
1955
24
I. Electrocardiographic changes in the intermediate coronary syndrome. ( 13211952 )
1954
Sources

Variations for Intermediate Coronary Syndrome

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Expression for Intermediate Coronary Syndrome

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Search GEO for disease gene expression data for Intermediate Coronary Syndrome.
Sources

Pathways for Intermediate Coronary Syndrome

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Pathways related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Response to elevated platelet cytosolic Ca2+ 66
Show member pathways
 12.94 F3 ITGA2B P2RY12 PLAT PLG SELP
2
Selenium Micronutrient Network 1
Show member pathways
 12.07 CRP IL6 PLAT PLG
3
Dilated cardiomyopathy (DCM) 37
Show member pathways
 11.91 ACE IL6 ITGA2B TNNI3
4
Microglia Activation During Neuroinflammation: Overview 65
Show member pathways
 11.77 IL6 PLAT PLG
5
Formation of Fibrin Clot (Clotting Cascade) 66
Show member pathways
 11.76 F3 PLAT PLG SERPINC1 VWF
6
Platelet activation 37
11.74 ITGA2B P2RY12 VWF
7
Platelet Aggregation Inhibitor Pathway, Pharmacodynamics 61
11.29 ITGA2B P2RY12 VWF
8
Complement and coagulation cascades 1 37
11.16 F3 PLAT PLG SERPINC1 VWF
9
amb2 Integrin signaling 1
10.94 IL6 PLAT PLG SELP
10
A-beta Pathways: Plaque Formation and APP Metabolism 65
10.86 ACE PLAT PLG
11
Overview of nanoparticle effects 1
10.79 CRP IL6
12
Dissolution of Fibrin Clot 66
10.57 PLAT PLG
Sources

GO Terms for Intermediate Coronary Syndrome

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Cellular components related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.97 ACE CRP F3 IL6 PLAT PLG
2 extracellular exosome GO:0070062 9.86 ACE ITGA2B MB PIK3C2A PLAT PLG
3 external side of plasma membrane GO:0009897 9.73 ACE ITGA2B P2RY12 SELP
4 cell surface GO:0009986 9.72 F3 ITGA2B P2RY12 PLAT PLG
5 extracellular space GO:0005615 9.56 ACE CRP F3 IL6 PLAT PLG
6 platelet alpha granule membrane GO:0031092 9.4 ITGA2B SELP
7 troponin complex GO:0005861 9.16 TNNI3 TNNT1
8 collagen-containing extracellular matrix GO:0062023 9.02 F3 PLAT PLG SERPINC1 VWF

Biological processes related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 platelet activation GO:0030168 9.63 IL6 P2RY12 VWF
2 platelet degranulation GO:0002576 9.56 ITGA2B PLG SELP VWF
3 fibrinolysis GO:0042730 9.49 PLAT PLG
4 regulation of muscle contraction GO:0006937 9.48 TNNI3 TNNT1
5 heart contraction GO:0060047 9.43 ACE TNNI3
6 blood coagulation GO:0007596 9.43 F3 P2RY12 PLAT PLG SERPINC1 VWF
7 positive regulation of leukocyte migration GO:0002687 9.4 ITGA2B SELP
8 negative regulation of lipid storage GO:0010888 9.37 CRP IL6
9 neutrophil mediated immunity GO:0002446 9.32 ACE IL6
10 slow-twitch skeletal muscle fiber contraction GO:0031444 9.16 MB TNNT1
11 hemostasis GO:0007599 9.02 F3 P2RY12 PLG SERPINC1 VWF

Molecular functions related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 9.13 F3 SERPINC1 VWF
2 troponin T binding GO:0031014 8.62 TNNI3 TNNT1
Sources

Sources for Intermediate Coronary Syndrome

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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