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MCID: INT007
MIFTS: 52

Intermediate Coronary Syndrome

Categories: Cardiovascular diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Intermediate Coronary Syndrome

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MalaCards integrated aliases for Intermediate Coronary Syndrome:

Name: Intermediate Coronary Syndrome 12 15
Angina, Unstable 44 73
Myocardial Preinfarction Syndrome 73
Anginal Chest Pain at Rest 12
Impending Infarction 12
Preinfarction Angina 12
Worsening Angina 12
Unstable Angina 12
Angina at Rest 12

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases
See all MalaCards categories (disease lists)
ICD10: 33


Sources

Summaries for Intermediate Coronary Syndrome

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MalaCards based summary : Intermediate Coronary Syndrome, also known as angina, unstable, is related to angina pectoris and vascular disease, and has symptoms including angina pectoris An important gene associated with Intermediate Coronary Syndrome is UBAP1 (Ubiquitin Associated Protein 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Folate Metabolism. The drugs Ticlopidine and Clopidogrel have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and kidney, and related phenotypes are cardiovascular system and homeostasis/metabolism

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Related Diseases for Intermediate Coronary Syndrome

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Diseases related to Intermediate Coronary Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 149)
# Related Disease Score Top Affiliating Genes
1 angina pectoris 28.2 ACE CRP F3 IL6 SERPINC1
2 vascular disease 25.9 ACE CRP F3 IL6 PLAT PLG
3 acute myocardial infarction 24.4 ACE CRP F3 ITGA2B MB PIK3C2A
4 myocardial infarction 21.6 ACE CRP F3 IL6 ITGA2B MB
5 coronary heart disease 1 11.1
6 familial isolated restrictive cardiomyopathy 10.9 TNNI3 TNNT2
7 fournier gangrene 10.6 F3 SERPINC1
8 renal artery obstruction 10.6 ACE SERPINC1
9 japanese spotted fever 10.6 CRP SERPINC1
10 granulomatous hepatitis 10.6 ACE CRP ITGA2B
11 sagittal sinus thrombosis 10.6 F3 SERPINC1
12 qualitative platelet defect 10.5 F3 SELP
13 thrombocytopenia due to platelet alloimmunization 10.5 ITGA2B SELP
14 restrictive cardiomyopathy 10.5 TNNI3 TNNT1 TNNT2
15 conjugate gaze palsy 10.5 F3 PLG
16 fibrinolytic defect 10.5 PLAT SERPINC1
17 aortic valve disease 1 10.5 ACE CRP TNNI3
18 rheumatic myocarditis 10.5 CRP TNNI3
19 cerebral falx meningioma 10.5 F3 PLG
20 intrinsic cardiomyopathy 10.5 ACE TNNI3 TNNT2
21 myocardial stunning 10.5 SERPINC1 TNNI3 TNNT2
22 inherited blood coagulation disease 10.5 F3 ITGA2B SERPINC1
23 aortic valve disease 2 10.5 ACE CRP TNNI3
24 tick paralysis 10.5 PIK3C2A TNNI3
25 peripheral vertigo 10.5 CRP F3 SERPINC1
26 argentine hemorrhagic fever 10.4 PLAT SERPINC1
27 hemorrhagic disease 10.4 F3 ITGA2B SERPINC1
28 thrombasthenia 10.4 F3 ITGA2B SELP
29 cardiac rupture 10.4 CRP PLAT
30 atrial standstill 1 10.4 ACE TNNI3 TNNT2
31 generalized atherosclerosis 10.4 ACE CRP SELP
32 glanzmann thrombasthenia 10.4 F3 ITGA2B SELP
33 alpha-2-plasmin inhibitor deficiency 10.3 PLG SERPINC1
34 virus associated hemophagocytic syndrome 10.3 MB PIK3C2A
35 subendocardial myocardial infarction 10.3 MB SERPINC1
36 carotid stenosis 10.3 ACE CRP SELP
37 femoral neuropathy 10.3 F3 PLG
38 interstitial myocarditis 10.3 MB PIK3C2A
39 lemierre's syndrome 10.3 CRP F3 PLG
40 heparin-induced thrombocytopenia 10.3 F3 SELP SERPINC1
41 anterior cranial fossa meningioma 10.3 F3 PLG
42 ligneous conjunctivitis 10.3 PLAT PLG
43 systemic scleroderma 10.3 ACE CRP SELP
44 fiedler's myocarditis 10.3 ACE PIK3C2A
45 metabolic encephalomyopathic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration 10.2 MB PIK3C2A
46 venous insufficiency 10.2 CRP PLAT SELP
47 marantic endocarditis 10.2 F3 PLAT SERPINC1
48 cold agglutinin disease 10.2 CRP IL6
49 purpura 10.2 CRP F3 ITGA2B SERPINC1
50 central retinal artery occlusion 10.2 PLAT PLG

Comorbidity relations with Intermediate Coronary Syndrome via Phenotypic Disease Network (PDN): (show top 50) (show all 104)


Acquired Thrombocytopenia Active Peptic Ulcer Disease
Acute Cystitis Acute Kidney Failure
Acute Myocardial Infarction Acute Stress Disorder
Allergic Urticaria Angina Pectoris
Anthracosis Anxiety
Aortic Aneurysm Aortic Atherosclerosis
Aortic Valve Disease 1 Aortic Valve Disease 2
Asbestosis Atrioventricular Block
Atrophic Gastritis Basilar Artery Insufficiency
Benign Essential Hypertension Benign Hypertensive Renal Disease
Bleeding Disorder, Platelet-Type, 11 Bronchitis
Cardiac Arrest Cardiac Arrhythmia
Cardiogenic Shock Cerebrovascular Disease
Chronic Intestinal Vascular Insufficiency Chronic Kidney Failure
Chronic Myocardial Ischemia Constrictive Pericarditis
Coronary Artery Aneurysm Deficiency Anemia
Diabetic Polyneuropathy Diaphragm Disease
Dressler's Syndrome Duodenitis
Dyskinesia of Esophagus Dysthymic Disorder
Esophagitis Familial Atrial Fibrillation
First-Degree Atrioventricular Block Gallbladder Disease
Gastroesophageal Reflux Generalized Atherosclerosis
Gout Heart Disease
Hemopericardium Hyperlipoproteinemia, Type I
Hyperlipoproteinemia, Type Iv Hyperlipoproteinemia, Type V

Graphical network of the top 20 diseases related to Intermediate Coronary Syndrome:



Diseases related to Intermediate Coronary Syndrome
Sources

Symptoms & Phenotypes for Intermediate Coronary Syndrome

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UMLS symptoms related to Intermediate Coronary Syndrome:


angina pectoris

MGI Mouse Phenotypes related to Intermediate Coronary Syndrome:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.25 TNNT2 SELP SERPINC1 TNNI3 IL6 PLG
2 homeostasis/metabolism MP:0005376 10.18 TNNT2 SELP SERPINC1 IL6 PLG ITGA2B
3 hematopoietic system MP:0005397 10.14 SELP SERPINC1 PLAT IL6 PLG ITGA2B
4 immune system MP:0005387 10.02 SELP SERPINC1 PLAT IL6 PLG ITGA2B
5 mortality/aging MP:0010768 10 TNNI3 TNNT2 SELP SERPINC1 PLAT IL6
6 muscle MP:0005369 9.7 TNNT1 TNNT2 TNNI3 PLAT IL6 MB
7 renal/urinary system MP:0005367 9.43 SELP SERPINC1 IL6 PLG ACE PIK3C2A
8 respiratory system MP:0005388 9.17 SELP TNNI3 PLAT IL6 PLG MB
Sources

Drugs & Therapeutics for Intermediate Coronary Syndrome

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Drugs for Intermediate Coronary Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 443)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
2
Clopidogrel Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 120202-66-6, 113665-84-2 60606
3
Warfarin Approved Phase 4,Phase 3 81-81-2 6691 54678486
4
Ramipril Approved Phase 4,Not Applicable 87333-19-5 5362129
5
Hydroxocobalamin Approved Phase 4,Phase 3,Not Applicable 13422-51-0 11953898 44475014
6
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Not Applicable 58-93-5 3639
7
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-78-2 2244
8
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 22916-47-8 4189
9
Colchicine Approved Phase 4,Phase 3,Phase 2 64-86-8 6167 2833
10
Febuxostat Approved Phase 4,Phase 3,Not Applicable 144060-53-7 134018
11
Etanercept Approved, Investigational Phase 4 185243-69-0
12
Nitroglycerin Approved, Investigational Phase 4,Phase 3,Not Applicable 55-63-0 4510
13
Fosinopril Approved Phase 4 98048-97-6 55891
14
Citalopram Approved Phase 4 59729-33-8 2771
15
Everolimus Approved Phase 4,Phase 3,Phase 2,Not Applicable 159351-69-6 6442177
16
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 33069-62-4 36314
17
Pravastatin Approved Phase 4,Phase 3,Not Applicable 81093-37-0 54687
18
Rivaroxaban Approved Phase 4,Phase 3,Phase 2 366789-02-8
19
Benzocaine Approved, Investigational Phase 4,Phase 3,Not Applicable 1994-09-7, 94-09-7 2337
20
Carvedilol Approved, Investigational Phase 4,Phase 3,Not Applicable 72956-09-3 2585
21
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 274693-27-5 9871419
22
Udenafil Approved, Investigational Phase 4 268203-93-6 6918523
23
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 53123-88-9 5284616 6436030 46835353
24 Benidipine Approved, Investigational Phase 4 105979-17-7
25
Pioglitazone Approved, Investigational Phase 4,Phase 3 111025-46-8 4829
26
Nicotine Approved Phase 4,Not Applicable 54-11-5 942 89594
27
Amlodipine Approved Phase 4,Phase 3,Not Applicable 88150-42-9 2162
28
Simvastatin Approved Phase 4,Phase 3,Phase 2,Not Applicable 79902-63-9 54454
29
Metformin Approved Phase 4,Phase 3,Phase 2 657-24-9 14219 4091
30
Varenicline Approved, Investigational Phase 4 249296-44-4 5310966
31
Alvimopan Approved, Investigational Phase 4 156053-89-3 5488548
32
Ezetimibe Approved Phase 4,Phase 3 163222-33-1 150311
33
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 772 46507594
34
Dopamine Approved Phase 4,Phase 3 51-61-6, 62-31-7 681
35
Valsartan Approved, Investigational Phase 4,Phase 3 137862-53-4 60846
36
Bivalirudin Approved, Investigational Phase 4,Phase 3,Phase 2 128270-60-0 16129704
37
Bisoprolol Approved Phase 4,Not Applicable 66722-44-9 2405
38
Nitric Oxide Approved Phase 4,Not Applicable 10102-43-9 145068 160954
39
Fluvastatin Approved Phase 4,Phase 3 93957-54-1 1548972
40
Chromium Approved Phase 4,Phase 2,Phase 3,Not Applicable 7440-47-3 27668
41
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492
42
Apixaban Approved Phase 4,Phase 3,Phase 2 503612-47-3 10182969
43
Bupropion Approved Phase 4,Phase 3 34841-39-9, 34911-55-2 444
44
Saxagliptin Approved Phase 4,Phase 3 361442-04-8 11243969
45
Mycophenolic acid Approved Phase 4 24280-93-1 446541
46
Isosorbide Dinitrate Approved, Investigational Phase 4 87-33-2 6883
47
Probucol Approved, Investigational Phase 4 23288-49-5 4912
48 Fondaparinux Approved, Investigational Phase 4,Phase 3 104993-28-4
49
Nicorandil Approved, Investigational Phase 4 65141-46-0 47528
50
Lornoxicam Approved, Investigational Phase 4 70374-39-9 5282204

Interventional clinical trials:

(show top 50) (show all 628)
# Name Status NCT ID Phase Drugs
1 Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome Unknown status NCT01372839 Phase 4 Atorvastatin;Statin
2 Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome Unknown status NCT02037412 Phase 4 Ticagrelor;Clopidogrel
3 Small Coronary Artery Treated by TAXUS Liberté Registry in Japan Unknown status NCT00955214 Phase 4
4 Coronary Angioplasty in Octogenarians With Emergent Coronary Syndromes Unknown status NCT02126202 Phase 4
5 Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study Unknown status NCT00688922 Phase 4 Pravastatin
6 Atrial Fibrillation and Ischemic Events With Rivaroxaban in Patients With Stable Coronary Artery Disease Study Unknown status NCT02642419 Phase 4 Rivaroxaban and single antiplatelet drug (aspirin, clopidogrel or prasugrel);Rivaroxaban
7 A Trial to Evaluate Efficacy of Heart-protecting Musk Pill Unknown status NCT01897805 Phase 4 Heart-protecting Musk Pill;Placebo
8 Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance Image Unknown status NCT01769482 Phase 4 Udenafil;placebo
9 Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome Unknown status NCT00815100 Phase 4 Ivabradine;Placebo
10 DECARD: Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome Unknown status NCT00140257 Phase 4 Escitalopram
11 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
12 Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Differences Between the Loading Dose of Prasugrel and Ticagrelor . Unknown status NCT02032303 Phase 4 Ticagrelor loading;Prasugrel loading
13 Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel Unknown status NCT02032290 Phase 4 ticagrelor loading;Clopidogrel loading
14 Ischemia In Hemodialysed Patients: Ivabradine Versus Carvedilol Unknown status NCT01425164 Phase 4 Ivabradine;Carvedilol
15 The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke Trial Unknown status NCT00724724 Phase 4 Butylphthalide Soft Capsules;Aspirin
16 Colchicine for Acute Coronary Syndromes Unknown status NCT01906749 Phase 4 Colchicine;Placebo
17 Vitamin D and Inflammatory Cytokine Levels After Acute Myocardial Infraction (MI) Unknown status NCT01115842 Phase 4 Vitamin D
18 The Beneficial Role of Percutaneous Coronary Intervention Over Optimal Medical Therapy in Elderly Patients With Coronary Artery Disease Unknown status NCT01508663 Phase 4 ARB, CCB, ACE-inhibitor, statin, Nitrate, Antiplate etc.
19 Etanercept Treating Patient With Acute ST Segment Elevated Myocardial Infarction Unknown status NCT01372930 Phase 4 Etanercept;saline
20 Revascularization in Heart Failure Trial – REHEAT 2 Unknown status NCT00388245 Phase 4
21 Benidipine and Hydrochlorothiazide in Fosinopril Treated Chronic Kidney Disease Patients With Hypertension Unknown status NCT02646397 Phase 4 Fosinopril;Benidipine;Hydrochlorothiazide
22 HOPE-2 Study (Heart Outcomes Prevention Evaluation-2 Study) Unknown status NCT00106886 Phase 4 Folic acid, vitamin B6 and B12 or placebo
23 Effects of Levothyroxine Supplementation in Patients With Systolic Heart Failure and Subclinical Hypothyroidism Unknown status NCT02316743 Phase 4 Levothyroxine supplementation
24 The Effect of Tongguan Capsule for MicroRNA Profiles in Coronary Heart Disease Patients Unknown status NCT02850627 Phase 4 Tongguan capsule;placebo capsule
25 Danhong Injection in the Treatment of Unstable Angina Pectoris Completed NCT02007187 Phase 4 Danhong injection;Placebo
26 Comparison of Administration Strategies of Ticagrelor in Patients With Unstable Angina Pectoris, a Pharmacokinetic / Pharmacodynamic Study Completed NCT02612116 Phase 4 Pulverized ticagrelor sublingually;Pulverized ticagrelor orally;Integral ticagrelor
27 Diagnosis and Treatment of Acute Coronary Syndrome in the ED & the Impact of Rapid Bedside cTnl on Outcome. Completed NCT00276432 Phase 4
28 Beta-cell Function in Glucose Abnormalities and Acute Myocardial Infarction Completed NCT00627744 Phase 4 Sitagliptin
29 Fondaparinux Trial With Unfractionated Heparin (UFH) During Revascularization in Acute Coronary Syndromes (ACS) Completed NCT00790907 Phase 4 fondaparinux background and standard dose UFH;Fondaparinux background and low dose heparin;Open label fondaparinux
30 Protective Effect of EPA on Cardiovascular Events Completed NCT00231738 Phase 4 Eicosapentaenoic acid ethyl ester(EPADEL Capsule 300 TM)
31 Conservative Non-Invasive Versus Routine Invasive Management in Coronary Artery Bypass Surgery Patients With Non ST Elevation Elevation Acute Coronary Syndrome Completed NCT01895751 Phase 4
32 Aspirin Non-responsiveness and Clopidogrel Endpoint Trial. Completed NCT00222261 Phase 4 aspirin;clopidogrel
33 The Effect of Pioglitazone on Neointima Volume and Characteristics Observed by Optical Coherence Tomography (OCT) Completed NCT01331967 Phase 4 Pioglitazone
34 A Randomized Evaluation of First-dollar Coverage for Post-MI Secondary Preventive Therapies Completed NCT00566774 Phase 4
35 Does Saxagliptin Reduce the Risk of Cardiovascular Events When Used Alone or Added to Other Diabetes Medications Completed NCT01107886 Phase 4 Saxagliptin;Placebo
36 Efficacy and Safety of Lornoxicam in Patients With Acute Coronary Syndrome Completed NCT00997750 Phase 4 Lornoxicam
37 Bupropion for Hospitalized Smokers With Acute Cardiovascular Disease Completed NCT00181818 Phase 4 bupropion SR (sustained-release)
38 Multiple Interventions Related to Dialysis Procedures in Order to Reduce Cardiovascular Morbidity and Mortality in HD Patients(EGESTUDY) Completed NCT00295191 Phase 4
39 Resistance to Aspirin and/or Clopidogrel Among Patients With PAD. Completed NCT00262561 Phase 4 Aspirin
40 Comparison of Post-dilution On-line Hemodiafiltration and Hemodialysis Completed NCT00411177 Phase 4
41 Prospective, Single-arm, Multicenter Study for Evaluation the Safety and Effectiveness of the ALEX Stent in a Real-world Setting of Percutaneous Coronary Interventions in Patients With Coronary Heart Disease Completed NCT01637012 Phase 4
42 Acarbose Cardiovascular Evaluation Trial Completed NCT00829660 Phase 4 Acarbose;Matching Placebo
43 The Effect of Atorvastatin and Pioglitazone on Carotid Atherosclerosis With the Use of Positron Emission Tomography-computed Tomography (PET-CT) Completed NCT01341730 Phase 4 Atorvastatin 20mg;Atorvastatin 20 mg + Pioglitazone 30 mg
44 DANish Multicenter STENT Trial Completed NCT00139802 Phase 4
45 Intensive Statin Treatment in Chinese Coronary Artery Disease Patients Undergoing PCI Completed NCT01293097 Phase 4 Atorvastatin;Statin
46 Effect of Pioglitazone on Insulin Resistance, Atherosclerosis Progression and Clinical Course of Coronary Heart Disease Completed NCT03011775 Phase 4 Pioglitazone 15 mg Tablet;Isosorbide Dinitrate 10Mg Tablet;Acetylsalicylic Acid 75Mg Tablet;Bisoprolol Fumarate 2.5 MG Oral Tablet;Rosuvastatin Calcium 20 MG Oral Tablet;ramipril 5 MG
47 Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression Completed NCT01212900 Phase 4 Statin Drugs
48 Incidence of Occluded Culprit Arteries and Impact of Coronary Collaterals on Outcome in Patients With NSTEMI Completed NCT01159366 Phase 4
49 Randomized Trial of Immediate Versus Early and Selective Invasive Percutaneous Coronary Intervention in NSTEMI Completed NCT00402675 Phase 4
50 Lipitor In The Prevention Of Stroke, For Patients Who Have Had A Previous Stroke Completed NCT00147602 Phase 4 atorvastatin

Search NIH Clinical Center for Intermediate Coronary Syndrome

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: angina, unstable

Sources

Genetic Tests for Intermediate Coronary Syndrome

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Sources

Anatomical Context for Intermediate Coronary Syndrome

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MalaCards organs/tissues related to Intermediate Coronary Syndrome:

41
Heart, Testes, Kidney, Endothelial, Lung, Prostate, Liver
Sources

Publications for Intermediate Coronary Syndrome

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Articles related to Intermediate Coronary Syndrome:

(show all 22)
# Title Authors Year
1
Management of intermediate coronary syndrome: role of conservative treatment, glycoprotein IIb/IIIa receptor inhibitors, and direct intervention. ( 11076127 )
2000
2
A prospective study of an algorithm using cardiac troponin I and myoglobin as adjuncts in the diagnosis of acute myocardial infarction and intermediate coronary syndromes in a veteran's hospital. ( 11129678 )
2000
3
Unstable angina pectoris. Platelet behavior and prognosis in progressive angina and intermediate coronary syndrome. ( 2136815 )
1990
4
Atenolol, heparin and the intermediate coronary syndrome. ( 6113419 )
1981
5
The intermediate coronary syndrome. ( 6971456 )
1981
6
Trial of heparin versus atenolol in prevention of myocardial infarction in intermediate coronary syndrome. ( 6112564 )
1981
7
Pathophysiologic significance of S-T and T wave abnormalities in patients with the intermediate coronary syndrome. ( 299974 )
1977
8
Long-term follow-up in patients receiving emergency revascularization for intermediate coronary syndrome. ( 4600203 )
1974
9
SURGICAL MANAGEMENT OF THE INTERMEDIATE CORONARY SYNDROME. ( 15215960 )
1974
10
Editorial: Intermediate coronary syndrome. ( 4148257 )
1973
11
The natural history of intermediate coronary syndrome. ( 4721961 )
1973
12
Bradycardia in intermediate coronary syndrome. ( 4723578 )
1973
13
Letter: Intermediate coronary syndrome. ( 4752330 )
1973
14
The intermediate coronary syndrome: clinical, angiographic and therapeutic aspects. ( 4144755 )
1973
15
Early diagnosis of acute myocardial infarction with special reference to the diagnosis of the intermediate coronary syndrome. A clinical study. ( 4586014 )
1972
16
Recognition and management of the intermediate coronary syndrome. ( 6021604 )
1967
17
Diagnosis and management of the intermediate coronary syndrome. A clinical study of 400 cases of the syndrome. ( 5932254 )
1966
18
THE INTERMEDIATE CORONARY SYNDROME. ( 14061336 )
1963
19
Intermediate coronary syndrome. ( 13779654 )
1961
20
Electrocardiographic changes in the intermediate coronary syndrome. II. Location of lesions. ( 13286446 )
1956
21
The intermediate coronary syndrome. ( 13226558 )
1955
22
I. Electrocardiographic changes in the intermediate coronary syndrome. ( 13211952 )
1954
Sources

Variations for Intermediate Coronary Syndrome

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Expression for Intermediate Coronary Syndrome

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Search GEO for disease gene expression data for Intermediate Coronary Syndrome.
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Pathways for Intermediate Coronary Syndrome

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Pathways related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1
Response to elevated platelet cytosolic Ca2+ 66
Show member pathways
 12.99 F3 ITGA2B P2RY12 PLAT PLG SELP
2
Folate Metabolism 1
Show member pathways
 12.04 CRP IL6 PLAT PLG
3
Formation of Fibrin Clot (Clotting Cascade) 66
Show member pathways
 11.82 F3 PLAT PLG SERPINC1
4
Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers 65
11.79 IL6 TNNI3 TNNT2
5
Complement and coagulation cascades 1 37
11.7 F3 PLAT PLG SERPINC1
6
Dilated cardiomyopathy (DCM) 37
Show member pathways
 11.59 ACE IL6 ITGA2B TNNI3 TNNT2
7
Striated Muscle Contraction 1 66
11.47 TNNI3 TNNT1 TNNT2
8
Overview of nanoparticle effects 1
10.76 CRP IL6
9
A-beta Pathways: Plaque Formation and APP Metabolism 65
10.69 ACE PLAT PLG
10
amb2 Integrin signaling 1
10.61 IL6 PLAT PLG SELP
11
Dissolution of Fibrin Clot 66
10.57 PLAT PLG
Sources

GO Terms for Intermediate Coronary Syndrome

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Cellular components related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.97 ACE CRP F3 ITGA2B MB PIK3C2A
2 cell surface GO:0009986 9.8 F3 ITGA2B P2RY12 PLAT PLG
3 extracellular space GO:0005615 9.76 ACE CRP F3 IL6 PLAT PLG
4 external side of plasma membrane GO:0009897 9.67 ACE ITGA2B P2RY12 SELP
5 platelet alpha granule membrane GO:0031092 9.43 ITGA2B SELP
6 cardiac myofibril GO:0097512 9.26 TNNI3 TNNT2
7 cardiac Troponin complex GO:1990584 8.96 TNNI3 TNNT2
8 troponin complex GO:0005861 8.8 TNNI3 TNNT1 TNNT2

Biological processes related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 9.71 ITGA2B PLG SELP
2 muscle contraction GO:0006936 9.7 TNNI3 TNNT1 TNNT2
3 cardiac muscle contraction GO:0060048 9.58 TNNI3 TNNT1 TNNT2
4 fibrinolysis GO:0042730 9.55 PLAT PLG
5 muscle filament sliding GO:0030049 9.54 TNNI3 TNNT1 TNNT2
6 positive regulation of leukocyte migration GO:0002687 9.51 ITGA2B SELP
7 heart contraction GO:0060047 9.49 ACE TNNI3
8 negative regulation of ATPase activity GO:0032780 9.48 TNNI3 TNNT2
9 neutrophil mediated immunity GO:0002446 9.46 ACE IL6
10 negative regulation of lipid storage GO:0010888 9.43 CRP IL6
11 skeletal muscle contraction GO:0003009 9.43 TNNI3 TNNT1 TNNT2
12 blood coagulation GO:0007596 9.35 F3 P2RY12 PLAT PLG SERPINC1
13 regulation of muscle contraction GO:0006937 9.33 TNNI3 TNNT1 TNNT2
14 slow-twitch skeletal muscle fiber contraction GO:0031444 9.32 MB TNNT1
15 hemostasis GO:0007599 8.92 F3 P2RY12 PLG SERPINC1

Molecular functions related to Intermediate Coronary Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tropomyosin binding GO:0005523 9.26 TNNT1 TNNT2
2 troponin T binding GO:0031014 9.16 TNNI3 TNNT1
3 troponin C binding GO:0030172 8.96 TNNI3 TNNT2
4 calcium-dependent ATPase activity GO:0030899 8.62 TNNT1 TNNT2
Sources

Sources for Intermediate Coronary Syndrome

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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