MCID: INT005
MIFTS: 22

Intermediate Malignant Teratoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Intermediate Malignant Teratoma

MalaCards integrated aliases for Intermediate Malignant Teratoma:

Name: Intermediate Malignant Teratoma 12 15
Malignant Teratoma, Intermediate 12 70
Intermediate Immature Teratoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7202
NCIt 50 C4288
SNOMED-CT 67 21912003
UMLS 70 C0334522

Summaries for Intermediate Malignant Teratoma

Disease Ontology : 12 A malignant teratoma characterized by the presence of an intermediate amount of undifferentiated tissues.

MalaCards based summary : Intermediate Malignant Teratoma, also known as malignant teratoma, intermediate, is related to triploidy and chromosomal triplication. An important gene associated with Intermediate Malignant Teratoma is AFP (Alpha Fetoprotein), and among its related pathways/superpathways is Glucocorticoid receptor regulatory network. Affiliated tissues include testis, placenta and lymph node.

Related Diseases for Intermediate Malignant Teratoma

Diseases in the Teratoma family:

Benign Teratoma Malignant Teratoma
Adult Teratoma Intermediate Malignant Teratoma

Diseases related to Intermediate Malignant Teratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 32)
# Related Disease Score Top Affiliating Genes
1 triploidy 10.1 PAPPA AFP
2 chromosomal triplication 10.1 PAPPA AFP
3 cystic lymphangioma 10.1 PAPPA AFP
4 patau syndrome 10.1 PAPPA AFP
5 orofaciodigital syndrome viii 10.1 PAPPA AFP
6 placenta accreta 10.1 PAPPA AFP
7 gestational trophoblastic neoplasm 10.1 PAPPA AFP
8 oligohydramnios 10.1 PAPPA AFP
9 malignant teratoma 10.0 TNFRSF8 AFP
10 ovarian solid teratoma 10.0 TNFRSF8 AFP
11 ovarian embryonal carcinoma 10.0 TNFRSF8 AFP
12 placental insufficiency 10.0 PAPPA AFP
13 testicular infarct 10.0 TNFRSF8 AFP
14 infected hydrocele 10.0 TNFRSF8 AFP
15 intratubular embryonal carcinoma 10.0 TNFRSF8 AFP
16 ectopic pregnancy 10.0 PAPPA AFP
17 mixed germ cell cancer 10.0 TNFRSF8 AFP
18 testicular malignant germ cell cancer 10.0 TNFRSF8 AFP
19 ovarian gonadoblastoma 10.0 TNFRSF8 AFP
20 mediastinal cancer 10.0 TNFRSF8 AFP
21 embryonal testis carcinoma 10.0 TNFRSF8 AFP
22 crigler-najjar syndrome, type i 10.0 CNDP2 AFP
23 mature teratoma 10.0 TNFRSF8 AFP
24 placenta disease 10.0 PAPPA AFP
25 endodermal sinus tumor 10.0 TNFRSF8 AFP
26 testicular disease 10.0 TNFRSF8 AFP
27 chromosomal duplication syndrome 9.9 PAPPA AFP
28 seminoma 9.8 TNFRSF8 AFP
29 chromosomal disease 9.8 PAPPA AFP
30 afibrinogenemia, congenital 9.7 FGG F10
31 hemorrhagic disease 9.6 FGG F10 AFP
32 thrombophilia 9.6 FGG F10

Graphical network of the top 20 diseases related to Intermediate Malignant Teratoma:



Diseases related to Intermediate Malignant Teratoma

Symptoms & Phenotypes for Intermediate Malignant Teratoma

Drugs & Therapeutics for Intermediate Malignant Teratoma

Search Clinical Trials , NIH Clinical Center for Intermediate Malignant Teratoma

Genetic Tests for Intermediate Malignant Teratoma

Anatomical Context for Intermediate Malignant Teratoma

MalaCards organs/tissues related to Intermediate Malignant Teratoma:

40
Testis, Placenta, Lymph Node

Publications for Intermediate Malignant Teratoma

Articles related to Intermediate Malignant Teratoma:

(show all 25)
# Title Authors PMID Year
1
Kit expression in male germ cell tumors. 61
17595797 2007
2
A 7-year audit in a single centre of the results of the modified template retroperitoneal lymph node dissection for testicular teratoma. 61
10510113 1999
3
Sequential resection of residual abdominal and thoracic masses after chemotherapy for metastatic non-seminomatous germ cell tumours. 61
7524606 1994
4
The superior mediastinal approach to hepatic malignancy. 61
8076713 1994
5
Results of the surveillance policy of stage I non-seminomatous germ cell testicular tumours. 61
1333336 1992
6
Glutathione S-transferase expression in the human testis and testicular germ cell neoplasia. 61
1355663 1992
7
Surgery following chemotherapy for metastatic testicular teratoma. 61
1913071 1991
8
Excision of residual masses after platinum based chemotherapy for non-seminomatous germ cell tumours. 61
2561098 1989
9
Findings in lymph nodes of patients with germ cell tumours after chemotherapy and their relation to prognosis. 61
2584406 1989
10
Testicular cancer in three brothers. 61
2608605 1989
11
Diagnosis of metastases from testicular germ cell tumours using fine needle aspiration cytology. 61
3693570 1987
12
[Experiences in the treatment of advanced nonseminomatous testicular tumor]. 61
2429460 1986
13
Pregnancy-associated plasma protein-A concentrations in men with testicular and prostatic tumors. 61
2427047 1986
14
Non-seminoma testis treated by irradiation at the Rotterdamsch Radio-Therapeutisch Instituut: the risk of metastasis. 61
6505280 1984
15
Orchiectomy alone for Stage I testicular non-seminoma. A progress report on the Royal Marsden Hospital study. 61
6317135 1983
16
The prevalence and prognostic significance of trophoblastic proteins in testicular teratoma. 61
6676077 1983
17
Orchidectomy alone in testicular stage I non-seminomatous germ-cell tumours. 61
6126625 1982
18
Radiation therapy of testicular non-seminomas. 61
6177670 1982
19
Non-seminoma germ cell tumours (malignant teratoma) of the testis. Results of treatment and an analysis of prognostic factors. 61
6165424 1981
20
Tumour-marker levels and prognosis in malignant teratoma of the testis. 61
6161630 1980
21
Seven cases of testicular tumors with two cryptorchidism. 61
6105754 1980
22
[Aspiration biopsy cytology in malignant tumors of the testis? (author's transl)]. 61
505689 1979
23
The staging of testicular tumors. 61
455237 1979
24
[Secreting tumors of the testis (author's transl)]. 61
878751 1977
25
Intracerebral metastatic malignant teratoma in the region of the optic chiasm. 61
1275862 1976

Variations for Intermediate Malignant Teratoma

Expression for Intermediate Malignant Teratoma

Search GEO for disease gene expression data for Intermediate Malignant Teratoma.

Pathways for Intermediate Malignant Teratoma

Pathways related to Intermediate Malignant Teratoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.54 FGG AFP

GO Terms for Intermediate Malignant Teratoma

Cellular components related to Intermediate Malignant Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum lumen GO:0005788 8.8 FGG F10 AFP

Biological processes related to Intermediate Malignant Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hemostasis GO:0007599 8.96 FGG F10
2 cellular protein metabolic process GO:0044267 8.8 PAPPA FGG AFP

Molecular functions related to Intermediate Malignant Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase activity GO:0008233 8.8 PAPPA F10 CNDP2

Sources for Intermediate Malignant Teratoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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