MCID: INT394
MIFTS: 21

Intermittent Asthma

Categories: Respiratory diseases

Aliases & Classifications for Intermittent Asthma

MalaCards integrated aliases for Intermittent Asthma:

Name: Intermittent Asthma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0080812

Summaries for Intermittent Asthma

Disease Ontology : 12 A chronic asthma that is characterized by severity with symptoms two or fewer days per week, nighttime awakenings two or fewer times per month, use of short-acting beta agonist for symptom control two or fewer days per week and no interference with normal activity.

MalaCards based summary : Intermittent Asthma is related to asthma and allergic rhinitis. An important gene associated with Intermittent Asthma is ADORA2A (Adenosine A2a Receptor). The drugs Budesonide and Fluticasone have been mentioned in the context of this disorder. Affiliated tissues include neutrophil, lung and skin.

Related Diseases for Intermittent Asthma

Diseases related to Intermittent Asthma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 asthma 29.9 RNASE3 ADORA2A
2 allergic rhinitis 10.0
3 rhinitis 10.0
4 bronchitis 10.0
5 respiratory allergy 9.8
6 exercise-induced bronchoconstriction 9.8
7 allergic asthma 9.8
8 hypereosinophilic syndrome 9.8
9 plastic bronchitis 9.8
10 malaria 9.5 RNASE3 ADORA2A

Graphical network of the top 20 diseases related to Intermittent Asthma:



Diseases related to Intermittent Asthma

Symptoms & Phenotypes for Intermittent Asthma

Drugs & Therapeutics for Intermittent Asthma

Drugs for Intermittent Asthma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 42)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Budesonide Approved Phase 4 51333-22-3 63006 5281004
2
Fluticasone Approved, Experimental Phase 4 90566-53-3 62924
3 Respiratory System Agents Phase 4
4 Anti-Asthmatic Agents Phase 4
5 Anti-Inflammatory Agents Phase 4
6 Hormones Phase 4
7 Hormone Antagonists Phase 4
8 Dermatologic Agents Phase 4
9 Bronchodilator Agents Phase 4
10 Anti-Allergic Agents Phase 4
11 glucocorticoids Phase 4
12
mometasone furoate Approved, Investigational, Vet_approved Phase 3 83919-23-7
13
Histamine Approved, Investigational Phase 3 51-45-6, 75614-87-8 774
14
Desloratadine Approved, Investigational Phase 3 100643-71-8 124087
15
Glutaral Experimental Phase 3 111-30-8 3485
16 Neurotransmitter Agents Phase 3
17 Cholinergic Antagonists Phase 3
18 Histamine Antagonists Phase 3
19
Histamine Phosphate Phase 3 51-74-1 65513
20 Histamine H1 Antagonists Phase 3
21 Histamine H1 Antagonists, Non-Sedating Phase 3
22 Cholinergic Agents Phase 3
23
Aluminum hydroxide Approved, Investigational Phase 2 21645-51-2
24
Terbutaline Approved Phase 2 23031-25-6 5403
25
Olodaterol Approved Phase 2 868049-49-4
26 Gastrointestinal Agents Phase 2
27 Immunologic Factors Phase 2
28 Antacids Phase 2
29 Anti-Ulcer Agents Phase 2
30 Adjuvants, Immunologic Phase 2
31 Adrenergic beta-Agonists Phase 2
32
Salmeterol xinafoate Phase 2 94749-08-3 56801
33 Adrenergic Agonists Phase 2
34 Adrenergic Agents Phase 2
35 Fluticasone-Salmeterol Drug Combination Phase 2
36 Tocolytic Agents Phase 2
37 Pharmaceutical Solutions Phase 2
38 Formoterol Fumarate Phase 2
39 Sympathomimetics Phase 2
40 Vaccines Phase 2
41 Albuterol Phase 1
42 Pulmonary Surfactants

Interventional clinical trials:

(show all 15)
# Name Status NCT ID Phase Drugs
1 Does a Lipophilic Steroid Inhaled After an Early Allergic Reaction Affect the Late Reaction? Completed NCT00716963 Phase 4 Fluticasone propionate (Flovent Diskus) 250 mcg;budesonide 400 mcg
2 Multicenter, Placebo-controlled, Long-term Study of Depigoid Birch 5000 in Adults and Adolescents With Allergic Rhinitis and/or Rhinoconjunctivitis With or Without Intermittent Asthma Completed NCT01694836 Phase 3
3 An Exploratory Study of Mometasone Furoate Nasal Spray in Patients With Moderate-severe Persistent Allergic Rhinitis and Intermittent Asthma: Effects on the Quality of Life Evaluated With the Rhinasthma Questionnaire Completed NCT00599027 Phase 3 Mometasone furoate nasal spray (MFNS);Placebo nasal spray
4 A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy and Safety of Intraseasonal Specific Short-term Immunotherapy With Depigmented Glutaraldehyde Polymerized Birch Pollen Allergenic Extract (Depiquick® Birch) in Patients With Allergic Rhinitis and/or Rhinoconjunctivitis With or Without Intermittent Asthma Completed NCT01902992 Phase 3 Depiquick Birch (DPG103);Placebo
5 Evaluation of the Efficacy and Safety of Desloratadine Syrup in Children Suffering From Seasonal Allergic Rhinitis With or Without Intermittent Asthma Completed NCT00805324 Phase 3 Desloratadine
6 A Randomised, Double-Blind, Parallel Group, Multicentre Study to Assess the Efficacy and Safety of Four Concentrations of Depigoid® Phleum in Patients With Allergic Rhinitis and/or Rhinoconjunctivitis With or Without Intermittent Asthma Completed NCT01634958 Phase 2
7 A Randomised, Open Label, Five-way Crossover Study to Assess the Systemic Exposure of Fluticasone Propionate and Salmeterol From SERETIDE/ADVAIR 250HFA MDI Alone and With AeroChamber-Max Spacer and VOLUMATIC Both in Their Washed and Unwashed States in Adult Subjects With Mild or Intermittent Asthma Completed NCT00369993 Phase 2 fluticasone propionate/salmeterol
8 Randomized, DB, Parallel Group, MC Study to Evaluate the Efficacy and Safety of Four Doses of Depigmented Glutaraldehyde Polymerized Birch Pollen Allergenic Extract (Depigoid Birch) in Patients With Allergic Rhinitis and/or Rhinoconjunctivitis With or Without Intermittent Asthma Completed NCT01144429 Phase 2
9 A Randomised, Double Blind, Placebo Controlled, Parallel-group Study With Use of Budesonide/Formoterol "As-needed", or Terbutaline "As-needed" or Regular Use of Budesonide + Terbutaline "As-needed", in Patients With Mild Intermittent Asthma Completed NCT00989833 Phase 2 budesonide;terbutaline;budesonide/formoterol
10 Randomised, Double-Blind, Placebo-Controlled, 5-Way Cross-Over Study to Assess the Efficacy (Bronchoprotection) and Safety of a Single Dose of Orally Inhaled BI 1744 CL (2, 5, 10 and 20ug) in Patients With Intermittent Asthma Completed NCT00928668 Phase 2 Placebo;Olodaterol (BI1744CL);Olodaterol (BI1744CL);Olodaterol (BI1744CL);Olodaterol (BI1744CL)
11 A Randomized, Double-Blind, Chronic-Dosing (14 Days), 5-Period, 7-Treatment, Placebo-Controlled, Incomplete Block, Cross-Over, Multicenter, Dose-ranging Study to Assess the Efficacy and Safety of PT001 Relative to Placebo Metered Dose Inhaler and Open-Label Serevent® Diskus® in Adult Subjects With Intermittent Asthma or Mild to Moderate Persistent Asthma Completed NCT02433834 Phase 2 Glycopyrronium MDI;Serevent Diskus 50 μg;Placebo
12 Clinical Exploring Study of Weiyang Yuping Decoction in Preventing Acute Attacks of Mild to Moderate Intermittent Asthma Based on the Theory of "Preventing Disease From Exacerbating" in Chinese Medicine Not yet recruiting NCT04522726 Phase 2 Weiyang Yuping Fang
13 Prospective Study to Evaluate the Safety of a 4-month Treatment With Depigoid® Dermatophagoides Pteronyssinus or 50% Dermatophagoides Pteronyssinus / 50% Dermatophagoides Farinae (500 DPP/ml) in Patients With Allergic Rhinitis or Rhinoconjunctivitis With or Without Mild Persistent or Intermittent Asthma Terminated NCT01591343 Phase 2
14 A Stepwise, Rising Dose Study of Male Subjects With Mild Intermittent Asthma to Assess the Topical Safety and Tolerability of Albuterol Sulfate Acu-30™ DPI Compared With Placebo Acu-30™ DPI Completed NCT00565591 Phase 1 Albuterol sulfate
15 Ex Vivo Effect of Fragments and Modified Forms of Surfactant Protein D on Pulmonary Immune Cells Derived From Bronchoalveolar Lavage After Segmental Allergen Challenge in Patients With Asthma and Pilot Study to Assess Local Inflammation Induced by Segmental Allergen Challenge by Magnetic Resonance Imaging Completed NCT01378624

Search NIH Clinical Center for Intermittent Asthma

Genetic Tests for Intermittent Asthma

Anatomical Context for Intermittent Asthma

MalaCards organs/tissues related to Intermittent Asthma:

40
Neutrophil, Lung, Skin, Spleen, Smooth Muscle, Kidney, Thyroid

Publications for Intermittent Asthma

Articles related to Intermittent Asthma:

(show top 50) (show all 354)
# Title Authors PMID Year
1
Mental Wellbeing and General Health in Adolescents with Asthma: The PIAMA Birth Cohort Study. 61
33548259 2021
2
Inhaled corticosteroids use in childhood respiratory diseases: an italian survey on pediatricians' prescription habits. 61
33588923 2021
3
Ineffective CPAP Treatment After Effective CPAP Titration. 61
33280775 2020
4
Managing Asthma in Adolescents and Adults: 2020 Asthma Guideline Update From the National Asthma Education and Prevention Program. 61
33270095 2020
5
The Impact of Food Histamine Intake on Asthma Activity: A Pilot Study. 61
33167542 2020
6
Sublingual immunotherapy for asthma. 61
32926419 2020
7
E-cigarette or Vaping Product Use-Associated Lung Injury Presenting as Sub-Acute Hypoxemia Without Increased Work of Breathing. 61
32963897 2020
8
Identifying Psychological Difficulties in College Athletes. 61
32209401 2020
9
Prevalence of asthma at a school-based health clinic in Nicaragua. 61
32040249 2020
10
Cardiac autonomic modulation assessed by heart rate variability in children with asthma. 61
32119199 2020
11
Determinants of severe exercise-induced bronchoconstriction in Nigerian children with asthma. 61
31990143 2020
12
Assessment of The Role of Serum Neutrophil Gelatinase-Associated Lipocalin in Egyptian Childhood Bronchial Asthma: One Centre Study. 61
33548981 2020
13
Validation of the breathmobile case identification survey for asthma screening in children with sickle cell disease. 61
32160791 2020
14
Persistent Asthma Is Associated With Increased Risk for Incident Atrial Fibrillation in the MESA. 61
32013555 2020
15
Documentation of asthma control and severity in pediatrics: analysis of national office-based visits. 61
30657001 2020
16
Assessment of Asthma Control and Quality of Life among Asthmatic Patients Attending Armed Forces Referral and Teaching Hospital, Addis Ababa, Ethiopia. 61
32802503 2020
17
Asthma co-morbidities in Nigerian children: prevalence, risk factors and association with disease severity and symptoms control. 61
32636989 2020
18
Thyrotoxic periodic paralysis presenting in an African-American teenage male: case report. 61
32346386 2020
19
An online survey detected knowledge gaps and cost-saving opportunities in asthma maintenance treatment among allergists, pulmonologists, ENTs and primary care. 61
31768217 2019
20
Lessons learned from clinical trials of asthma. 61
31690382 2019
21
[A neglected bronchial foreign body for 23 years]. 61
31521433 2019
22
Monitoring of respiratory resistance in the diagnosis of mild intermittent asthma. 61
30801802 2019
23
Short-course administration of a traditional herbal mixture ameliorates asthma symptoms of the common cold in children. 61
30984577 2019
24
A 31-Year-Old Man With Airflow Obstruction, Intrathoracic Adenopathy, and Pulmonary Nodules. 61
30732704 2019
25
Association of plasma soluble CD14 level with asthma severity in adults: a case control study in China. 61
30691461 2019
26
Diagnosis and Treatment of Asthma in Nonpregnant Women. 61
30484945 2019
27
Simultaneous Bilateral Primary Spontaneous Pneumothorax: A Case Report and a Review of the Literature. 61
30809412 2019
28
Leukotriene E4 induces airflow obstruction and mast cell activation through the cysteinyl leukotriene type 1 receptor. 61
29518425 2018
29
The effect of balance training intervention on postural stability in children with asthma. 61
28699850 2018
30
Short-term respiratory effects of e-cigarettes in healthy individuals and smokers with asthma. 61
28944531 2018
31
Asthma exacerbations: risk factors for hospital readmissions. 61
28593573 2018
32
Four Months of a School-Based Exercise Program Improved Aerobic Fitness and Clinical Outcomes in a Low-SES Population of Normal Weight and Overweight/Obese Children With Asthma. 61
30619785 2018
33
Safety Review of 5-Grass Pollen Tablet from Pooled Data of Clinical Trials. 61
28734858 2017
34
The Differences in Serum Quantitative Specific IgE Levels Induced by Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis Sensitization in Intermittent and Persistent Allergic Asthma. 61
29348379 2017
35
The Role of Oxidative Stress in the Clinical Manifestations of Childhood Asthma. 61
28481134 2017
36
Inhaled corticosteroids improve lung function, airway hyper-responsiveness and airway inflammation but not symptom control in patients with mild intermittent asthma: A meta-analysis. 61
28810625 2017
37
Perceptions of asthma control in the United Kingdom: a cross-sectional study comparing patient and healthcare professionals' perceptions of asthma control with validated ACT scores. 61
28801654 2017
38
Risk factors hindering asthma symptom control in Saudi children and adolescents. 61
28218986 2017
39
Estimate of the total costs of allergic rhinitis in specialized care based on real-world data: the FERIN Study. 61
27886391 2017
40
Association Between Migraine and Atopic Diseases in Childhood: A Potential Protective Role of Anti-Allergic Drugs. 61
28160287 2017
41
Factors associated with childhood asthma control in a resource-poor center. 61
29302522 2017
42
[Socioeconomic Costs of Asthma in the European Union, United States and Canada: A Systematic Review]. 61
28278149 2017
43
Bifidobacterium mixture (B longum BB536, B infantis M-63, B breve M-16V) treatment in children with seasonal allergic rhinitis and intermittent asthma. 61
28270216 2017
44
House dust mite sublingual tablet is effective and safe in patients with allergic rhinitis. 61
27471838 2017
45
Should recommendations about starting inhaled corticosteroid treatment for mild asthma be based on symptom frequency: a post-hoc efficacy analysis of the START study. 61
27912982 2017
46
Exposure to secondhand smoke and asthma severity among children in Connecticut. 61
28362801 2017
47
Epidemiology, triggers, and severity of childhood asthma in Ilesa, Nigeria: Implications for management and control. 61
29238123 2017
48
Asthma Severity and the Controller Prescription in Children at 12 Tertiary Hospitals. 61
27826962 2017
49
Prevalence and determinants of asthma in adults in Kinshasa. 61
28464036 2017
50
[Quality of life and associated factors in asthma in a Primary Care Center. Application of the reduced version of the Asthma Quality of Life Questionnaire]. 61
26858229 2016

Variations for Intermittent Asthma

Expression for Intermittent Asthma

Search GEO for disease gene expression data for Intermittent Asthma.

Pathways for Intermittent Asthma

GO Terms for Intermittent Asthma

Sources for Intermittent Asthma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....