MCID: INT047
MIFTS: 21

Internal Hordeolum

Categories: Endocrine diseases, Eye diseases, Infectious diseases, Skin diseases

Aliases & Classifications for Internal Hordeolum

MalaCards integrated aliases for Internal Hordeolum:

Name: Internal Hordeolum 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:9908
ICD9CM 34 373.12
SNOMED-CT 67 397514009
ICD10 32 H00.02
UMLS 70 C0085690

Summaries for Internal Hordeolum

MalaCards based summary : Internal Hordeolum is related to meibomian cyst and hordeolum. An important gene associated with Internal Hordeolum is MTRNR2L6 (MT-RNR2 Like 6), and among its related pathways/superpathways is all-trans-Retinoic Acid Mediated Apoptosis. Related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 73 Chalazion (also known as Meibomian cyst) is a cyst in the eyelid due to a blocked oil gland. They are... more...

Related Diseases for Internal Hordeolum

Graphical network of the top 20 diseases related to Internal Hordeolum:



Diseases related to Internal Hordeolum

Symptoms & Phenotypes for Internal Hordeolum

GenomeRNAi Phenotypes related to Internal Hordeolum according to GeneCards Suite gene sharing:

26 (show all 14)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-105 9.55 GUK1
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-115 9.55 IFNA1
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.55 IFNA1
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-142 9.55 GK
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-162 9.55 GK
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-178 9.55 IFNA1 IFNA2
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-195 9.55 IFNA1
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-20 9.55 IFNA2
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-214 9.55 GUK1 IFNA1
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-34 9.55 IFNA1
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-63 9.55 GUK1 IFNA1
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-73 9.55 IFNA1
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.55 GK
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-88 9.55 IFNA1

Drugs & Therapeutics for Internal Hordeolum

Search Clinical Trials , NIH Clinical Center for Internal Hordeolum

Genetic Tests for Internal Hordeolum

Anatomical Context for Internal Hordeolum

Publications for Internal Hordeolum

Articles related to Internal Hordeolum:

# Title Authors PMID Year
1
Acupuncture for acute hordeolum. 61
28181687 2017
2
Non-surgical interventions for acute internal hordeolum. 61
28068454 2017
3
Hemorrhagic pyogenic granuloma after internal hordeolum. 61
25625065 2014
4
Interventions for acute internal hordeolum. 61
23633345 2013
5
Interventions for acute internal hordeolum. 61
20824865 2010
6
Extensive corneal epithelial defect associated with internal hordeolum after uneventful laser in situ keratomileusis. 61
12231335 2002
7
[Studies on fortimicin in the field of ophthalmology]. 61
7131765 1982
8
[Ophthalmic application of intravenous cephradine (author's transl)]. 61
1003679 1976

Variations for Internal Hordeolum

Expression for Internal Hordeolum

Search GEO for disease gene expression data for Internal Hordeolum.

Pathways for Internal Hordeolum

Pathways related to Internal Hordeolum according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.3 IFNA2 IFNA1

GO Terms for Internal Hordeolum

Biological processes related to Internal Hordeolum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to cytokine GO:0034097 9.48 TYMS REL
2 humoral immune response GO:0006959 9.46 IFNA2 IFNA1
3 negative regulation of signaling receptor activity GO:2000272 9.43 MTRNR2L6 MTRNR2L5
4 response to exogenous dsRNA GO:0043330 9.4 IFNA2 IFNA1
5 B cell proliferation GO:0042100 9.37 IFNA2 IFNA1
6 nucleobase-containing small molecule interconversion GO:0015949 9.32 TYMS GUK1
7 T cell activation involved in immune response GO:0002286 9.26 IFNA2 IFNA1
8 positive regulation of peptidyl-serine phosphorylation of STAT protein GO:0033141 9.16 IFNA2 IFNA1
9 negative regulation of execution phase of apoptosis GO:1900118 8.96 MTRNR2L6 MTRNR2L5
10 natural killer cell activation involved in immune response GO:0002323 8.62 IFNA2 IFNA1

Molecular functions related to Internal Hordeolum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine receptor binding GO:0005126 9.16 IFNA2 IFNA1
2 receptor antagonist activity GO:0048019 8.96 MTRNR2L6 MTRNR2L5
3 type I interferon receptor binding GO:0005132 8.62 IFNA2 IFNA1

Sources for Internal Hordeolum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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