MCID: INT067
MIFTS: 50

Interstitial Nephritis

Categories: Nephrological diseases

Aliases & Classifications for Interstitial Nephritis

Summaries for Interstitial Nephritis

MalaCards based summary : Interstitial Nephritis, also known as nephritis, interstitial, is related to hypoaldosteronism and pyelitis. An important gene associated with Interstitial Nephritis is FAN1 (FANCD2 And FANCI Associated Nuclease 1), and among its related pathways/superpathways are Peptide hormone metabolism and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics. The drugs Pantoprazole and Cefixime have been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and bone, and related phenotypes are homeostasis/metabolism and immune system

Wikipedia : 76 Interstitial nephritis (or tubulo-interstitial nephritis) is a form of nephritis affecting the... more...

Related Diseases for Interstitial Nephritis

Diseases related to Interstitial Nephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 249)
# Related Disease Score Top Affiliating Genes
1 hypoaldosteronism 32.5 ACE REN
2 pyelitis 31.3 CRP REN
3 acute pyelonephritis 30.9 ALB CRP
4 iga glomerulonephritis 30.3 ACE ALB REN
5 pyelonephritis 29.8 ACE ALB CRP UMOD
6 acute kidney tubular necrosis 29.8 ALB UMOD
7 granulomatous hepatitis 29.6 ACE CRP PDCD1
8 microvascular complications of diabetes 3 29.0 ACE AGT ALB REN
9 hyperuricemia 28.6 CRP REN UMOD
10 nephronophthisis 28.3 ANKS6 CEP164 INVS MAPKBP1 UMOD
11 kidney disease 26.9 ACE AGT ALB CRP REN UMOD
12 end stage renal failure 26.6 ACE AGT ALB ANKS6 CRP UMOD
13 chronic kidney failure 26.4 ACE AGT ALB CRP INVS REN
14 interstitial nephritis, karyomegalic 12.7
15 megalocytic interstitial nephritis 12.5
16 danubian endemic familial nephropathy 11.3
17 nephronophthisis 2 11.0
18 nephronophthisis 15 11.0
19 nephronophthisis 16 11.0
20 nephronophthisis 20 11.0
21 infantile nephronophthisis 10.8 ANKS6 INVS
22 chronic pyelonephritis 10.8
23 hyporeninemic hypoaldosteronism 10.7 ACE REN
24 renal artery obstruction 10.6 ACE REN
25 hypertensive encephalopathy 10.6 ACE REN
26 benign essential hypertension 10.6 ALB REN
27 hypertensive retinopathy 10.6 ACE REN
28 renal artery disease 10.6 ACE REN
29 hypertensive nephropathy 10.6 ACE ALB
30 hypertension, diastolic 10.6 ACE REN
31 syndrome of inappropriate antidiuretic hormone 10.6 ACE ALB
32 kidney papillary necrosis 10.6 ALB REN
33 atrial septal defect 4 10.6 ACE REN
34 juvenile nephronophthisis 10.6 ANKS6 INVS MAPKBP1
35 malignant essential hypertension 10.6 ACE REN
36 generalized atherosclerosis 10.5 ACE CRP
37 abdominal tuberculosis 10.4 ALB CRP
38 pyuria 10.4 ALB CRP
39 angina pectoris 10.4 ACE CRP
40 chronic ulcer of skin 10.4 ALB CRP
41 decubitus ulcer 10.4 ALB CRP
42 subdural empyema 10.4 ACE CRP
43 pediatric hypertension 10.4 ACE AGT
44 hypersensitivity reaction type iii disease 10.3 ALB CRP
45 ischemic heart disease 10.3 ACE CRP
46 tuberculous peritonitis 10.3 ALB CRP
47 intermediate coronary syndrome 10.3 ACE CRP
48 hepatic vascular disease 10.3 ALB REN
49 orthostatic proteinuria 10.3 ACE ALB REN
50 posterior urethral valves 10.3 ACE AGT

Graphical network of the top 20 diseases related to Interstitial Nephritis:



Diseases related to Interstitial Nephritis

Symptoms & Phenotypes for Interstitial Nephritis

MGI Mouse Phenotypes related to Interstitial Nephritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.1 REN UMOD ACE AGT ALB APRT
2 immune system MP:0005387 9.86 ACE AGT APRT CRP INVS PDCD1
3 liver/biliary system MP:0005370 9.7 ACE AGT ALB ANKS6 FAN1 INVS
4 mortality/aging MP:0010768 9.65 ACE AGT ALB ANKS6 APRT CEP164
5 renal/urinary system MP:0005367 9.28 ACE AGT ALB APRT FAN1 INVS

Drugs & Therapeutics for Interstitial Nephritis

Drugs for Interstitial Nephritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 158)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pantoprazole Approved Phase 4 102625-70-7 4679
2
Cefixime Approved, Investigational Phase 4 79350-37-1 54362 5362065
3
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
4
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2 85721-33-1 2764
5
Nitrofurantoin Approved, Vet_approved Phase 4,Phase 3 67-20-9 5353830
6
Sulfamethoxazole Approved Phase 4,Phase 3 723-46-6 5329
7
Trimethoprim Approved, Vet_approved Phase 4,Phase 3 738-70-5 5578
8
Levofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2 100986-85-4 149096
9
Ofloxacin Approved Phase 4,Phase 3,Phase 2 82419-36-1 4583
10
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613
11
Cephalexin Approved, Investigational, Vet_approved Phase 4 15686-71-2 27447
12
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 59-30-3 6037
13
leucovorin Approved, Nutraceutical Phase 4,Phase 3 58-05-9 143 6006
14 Gastrointestinal Agents Phase 4,Phase 3
15 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Not Applicable
16 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Not Applicable
17 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Not Applicable
18 Antitubercular Agents Phase 4,Phase 3,Not Applicable
19 Topoisomerase Inhibitors Phase 4,Phase 3,Phase 2
20 Fluoroquinolones Phase 4,Phase 2
21 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2
22 Antacids Phase 4
23 Anti-Ulcer Agents Phase 4
24 Proton Pump Inhibitors Phase 4
25 Cytochrome P-450 CYP1A2 Inhibitors Phase 4,Phase 3,Phase 2
26 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2
27 Antimalarials Phase 4,Phase 3
28 Antiparasitic Agents Phase 4,Phase 3
29 Antiprotozoal Agents Phase 4,Phase 3
30 Folic Acid Antagonists Phase 4,Phase 3
31 Renal Agents Phase 4,Phase 3,Phase 2
32 Trimethoprim, Sulfamethoxazole Drug Combination Phase 4,Phase 3
33 Vitamin B Complex Phase 4,Phase 3
34 Amdinocillin Pivoxil Phase 4
35 Folate Nutraceutical Phase 4,Phase 3
36 Vitamin B9 Nutraceutical Phase 4,Phase 3
37
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
38
Fosfomycin Approved Phase 2, Phase 3 23155-02-4 446987
39
Piperacillin Approved Phase 2, Phase 3,Phase 3 66258-76-2 43672
40
Tazobactam Approved Phase 2, Phase 3,Phase 3 89786-04-9 123630
41
Meropenem Approved, Investigational Phase 3,Phase 2 119478-56-7 64778 441130
42 Avibactam Approved Phase 3 1192500-31-4
43
Ceftazidime Approved Phase 3,Phase 2 78439-06-2, 72558-82-8 5481173
44
Colistin Approved Phase 3 1264-72-8, 1066-17-7 5311054
45
Minocycline Approved, Investigational Phase 3 10118-90-8 5281021
46
Tigecycline Approved Phase 3 220620-09-7 5282044
47
Prednisone Approved, Vet_approved Phase 3,Phase 2 53-03-2 5865
48
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
49
Cytarabine Approved, Investigational Phase 3 147-94-4 6253
50
Daunorubicin Approved Phase 3 20830-81-3 30323

Interventional clinical trials:

(show top 50) (show all 73)
# Name Status NCT ID Phase Drugs
1 Stress Ulcer Prophylaxis in the Intensive Care Unit Completed NCT02467621 Phase 4 Pantoprazole
2 Efficacy and Safety Study of Short-term Antibiotic for Pyelonephritis in Women Completed NCT01390623 Phase 4 Ceftriaxone
3 Treatment of Acute Pyelonephritis With Gram Negative Strains in Infants and Children Less Than 3 Years Old Completed NCT00136656 Phase 4 antibiotic;antibiotics
4 Pharmacokinetics of Ciprofloxacin in Pediatric Patients Completed NCT02598362 Phase 4 ciprofloxacin
5 A Randomized Controlled Trial on Antibiotic Prophylaxis in Children With Vesico-Ureteral Reflux Completed NCT00382343 Phase 4 Sulfamethoxazole/trimethoprim
6 Treatment's Duration of Acute Uncomplicated Pyelonephritis Completed NCT00873626 Phase 4 levofloxacin, ciprofloxacin and ofloxacin (fluoroquinolones)
7 Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication Completed NCT02246361 Phase 4
8 Impact on the Intestinal Microbiota of Treatment With Ceftriaxone in Women's Acute Community Pyelonephritis Recruiting NCT03179384 Phase 4 Ceftriaxone
9 Treating Pyelonephritis an Urosepsis With Pivmecillinam Recruiting NCT03282006 Phase 4 pivmecillinam
10 Management of Sub-Clinical Bacteriuria in Pregnancy Recruiting NCT03275623 Phase 4 Antibiotic
11 Safety and Efficacy Study of the Treatment of Kidney Infections With Short Course Levofloxacin Terminated NCT00239161 Phase 4 Levofloxacin
12 ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot Study Unknown status NCT02155803 Phase 2, Phase 3 ACTHAR Gel (adrenocorticotropic hormone)
13 Oral Omega-3 for Reduction of Kidney Scar Due to Pyelonephritis in Children Unknown status NCT02192580 Phase 3 Omega-3
14 L-carnitine on the Prevention of Renal Scarring in Acute Pyelonephritis Unknown status NCT02007889 Phase 3 L-carnitine
15 CSE-1034 (Ceftriaxone+ Sulbactam+ EDTA) Compared to Meropenem in Complicated Urinary Tract Infections (cUTIs) Caused by ESBL Producing Gram Negative Bacteria Completed NCT03477422 Phase 3 CSE-1034 (Ceftriaxone + Sulbactam + EDTA);Meropenem
16 Safety and Efficacy of ZTI-01 (IV Fosfomycin) vs Piperacillin/Tazobactam for Treatment cUTI/AP Infections Completed NCT02753946 Phase 2, Phase 3 ZTI-01;Piperacillin-tazobactam
17 Study of Ceftolozane/Tazobactam (MK-7625A) in Japanese Participants With Uncomplicated Pyelonephritis and Complicated Urinary Tract Infection (MK-7625A-014) Completed NCT02728089 Phase 3 MK-7625A 1.5 g (ceftolozane 1 g/tazobactam 0.5 g)
18 A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP) Completed NCT02486627 Phase 3 plazomicin;meropenem;levofloxacin (oral)
19 Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP Completed NCT02166476 Phase 3 Meropenem-Vaborbactam;Piperacillin-Tazobactam;Levofloxacin;Saline
20 Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections) Completed NCT01599806 Phase 3 Ceftazidime - Avibactam ( CAZ-AVI);Doripenem;Either switch to oral therapy: 500 mg of Ciprofloxacin (oral);or switch to oral therapy: 800 mg/160 mg of sulfamethoxazole/trimethoprim (oral)
21 Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections) Completed NCT01595438 Phase 3 Ceftazidime - Avibactam ( CAZ-AVI);Doripenem;Either switch to oral therapy: 500 mg of Ciprofloxacin (oral);or switch to oral therapy: 800 mg/160 mg of sulfamethoxazole/trimethoprim (oral)
22 Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Levofloxacin in Complicated Urinary Tract Infection, Including Pyelonephritis Completed NCT01345929 Phase 3 CXA-201;Levofloxacin
23 Doripenem in the Treatment of Complicated Lower Urinary Tract Infection or Pyelonephritis Completed NCT00229021 Phase 3 doripenum
24 Doripenem in the Treatment of Complicated Lower Urinary Tract Infection or Pyelonephritis Completed NCT00210990 Phase 3 doripenem
25 A Comparison of the Effectiveness and Safety of Levofloxacin to That of Ciprofloxacin in Treating Complicated Urinary Tract Infection and Acute Pyelonephritis. Completed NCT00210886 Phase 3 levofloxacin
26 A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in the Treatment of Complicated Urinary Tract Infections Completed NCT00258089 Phase 3 Levofloxacin
27 A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE) Completed NCT01970371 Phase 3 plazomicin;colistin;meropenem;tigecycline;antibiotic of Investigator's choice
28 Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults Completed NCT02168946 Phase 3 Vabomere;Best Available Therapy
29 International Collaborative Treatment Protocol For Children And Adolescents With Acute Lymphoblastic Leukemia Active, not recruiting NCT01117441 Phase 3 PEG-L-asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;etoposide;ifosfamide;mercaptopurine;methotrexate;prednisone;thioguanine;vincristine sulfate;vindesine;daunoxome;fludarabine
30 Short-term Antibiotic Therapy for Pyelonephritis in Childhood Terminated NCT00724256 Phase 3 ceftibuten;ceftibuten
31 A Safety and Tolerability Study of Doripenem Compared With Cefepime in Children Hospitalized With Complicated Urinary Tract Infections Terminated NCT01110408 Phase 3 Doripenem;Doripenem placebo;Cefepime;Cefepime placebo;Amoxicillin/clavulanate potassium
32 Antibiotic Prophylaxis in Children With Pyelonephritis Withdrawn NCT00752375 Phase 3 Trimethoprim Sulfamethoxazole;placebo
33 Renal Effects of an Angiotensin Converting Enzyme Inhibitor in Adults With Chronic Kidney Disease of Uncertain Aetiology Unknown status NCT01624064 Phase 1, Phase 2 Enalapril;Calcium Supplement
34 Sitafloxacin and Ertapenem Treatment for Acute Pyelonephritis Caused by Escherichia Coli Unknown status NCT02537847 Phase 2 Sitafloxacin;Ertapenem
35 Rituximab in IgG4-RD: A Phase 1-2 Trial Completed NCT01584388 Phase 1, Phase 2 Rituximab
36 Effect of Acetylcysteine in Pediatric Acute Pyelonephritis. Completed NCT02080182 Phase 2 Acetylcysteine;placebo acetylcysteine
37 Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract Infections Completed NCT03445195 Phase 2 Sulbactam-ETX2514;Placebo;Imipenem-cilastatin
38 A Study of Efficacy/Safety of Intravenous S-649266 Versus Imipenem/Cilastatin in Complicated Urinary Tract Infections Completed NCT02321800 Phase 2 S-649266;Imipenem/cilastatin
39 Study of the Safety, Tolerability, and Efficacy of MK-7655 + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone for the Treatment of Complicated Urinary Tract Infection (cUTI) (MK-7655-003) Completed NCT01505634 Phase 2 MK-7655 250 mg;MK-7655 125 mg;imipenem/cilastatin 500 mg;Placebo to MK-7655;Ciprofloxacin
40 Study of Plazomicin (ACHN-490) Compared With Levofloxacin for the Treatment of Complicated Urinary Tract Infection and Acute Pyelonephritis Completed NCT01096849 Phase 2 levofloxacin;plazomicin;placebo
41 Safety and Efficacy of IV CXA-101 and IV Ceftazidime in Patients With Complicated Urinary Tract Infections Completed NCT00921024 Phase 2 CXA-101;Ceftazidime
42 Finafloxacin for the Treatment of cUTI and/or Acute Pyelonephritis Completed NCT01928433 Phase 2 Finafloxacin 800 mg i.v. once daily;Finafloxacin placebo i.v. once daily;Finafloxacin 800 mg tablets once daily;Finafloxacin placebo tablets once daily;Ciprofloxacin 400 mg i.v. twice daily;Ciprofloxacin placebo i.v. twice daily;Ciprofloxacin 500 mg oral twice daily;Ciprofloxacin placebo oral twice daily
43 Xolair (Omalizumab) for Treatment of Drug-induced Acute Tubulointerstitial Nephritis (AIN) Recruiting NCT01893658 Phase 2 Omalizumab;Prednisone
44 MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034) Recruiting NCT03230838 Phase 2 Ceftolozane;Tazobactam;Meropenem
45 Phase II Clinical Trial of NIVO-IPI-TAXANE in Untreated Metastatic NSCLC Not yet recruiting NCT03573947 Phase 2 Nivolumab;Ipilimumab;Paclitaxel
46 GSK2251052 in Complicated Urinary Tract Infection Terminated NCT01381549 Phase 2 GSK2251052;imipenem-cilastatin
47 Prospective Study in the Emergency Terminated NCT01628900 Phase 2
48 Anti-BK Virus Immune Response and Kidney Transplantation Unknown status NCT01109186
49 Dexamethasone Administration in 1st Episode of Febrile Urinary Tract Infection Unknown status NCT02034851
50 Antibiotic Treatment Versus no Therapy in Kidney Transplant Recipients With Asymptomatic Bacteriuria Unknown status NCT01771432 Not Applicable Antibiotic treatment

Search NIH Clinical Center for Interstitial Nephritis

Cochrane evidence based reviews: nephritis, interstitial

Genetic Tests for Interstitial Nephritis

Anatomical Context for Interstitial Nephritis

MalaCards organs/tissues related to Interstitial Nephritis:

41
Kidney, Liver, Bone, T Cells, Thyroid, Testes, Spleen

Publications for Interstitial Nephritis

Articles related to Interstitial Nephritis:

(show top 50) (show all 676)
# Title Authors Year
1
Granulomatous interstitial nephritis associated with silica. ( 29346841 )
2018
2
Acute Kidney Injury due to granulomatous interstitial nephritis induced by tramadol administration. ( 29471961 )
2018
3
Chronic kidney disease mortality trends in selected Central America countries, 1997-2013: clues to an epidemic of chronic interstitial nephritis of agricultural communities. ( 29437864 )
2018
4
Chronic granulomatous interstitial nephritis and urothelial metaplasia associated with ritonavir-boosted atazanavir: a case study and literature review. ( 29941201 )
2018
5
Spontaneous perirenal urinoma induced by NSAID-associated acute interstitial nephritis. ( 29615838 )
2018
6
Membranoproliferative glomerulonephritis and interstitial nephritis in the setting of Epstein-Barr virus-related hemophagocytic syndromea8c. ( 29350173 )
2018
7
First case of acute granulomatous interstitial nephritis with immune reconstitution inflammatory syndrome in a patient with HIV coinfected with disseminated <i>Mycobacterium kansasii</i>. ( 29477993 )
2018
8
Acute cellular rejection with coexisting tuberculous interstitial nephritis in renal allograft. ( 29456234 )
2018
9
Drug-induced acute interstitial nephritis: Prospective randomized trial comparing oral steroids and high-dose intravenous pulse steroid therapy in guiding the treatment of this condition. ( 29970736 )
2018
10
Acute interstitial nephritis: a multifaceted disease. ( 29744094 )
2018
11
Interstitial Nephritis Secondary to Vedolizumab Treatment in Crohn Disease and Safe Rechallenge Using Steroids: A Case Report. ( 29162338 )
2018
12
Successful use of rituximab in glomerular basement membrane nephritis associated withA HIV interstitial nephritis secondary to Castleman diseasea8c. ( 29424337 )
2018
13
Granulomatous interstitial nephritis secondary to adalimumab therapy. ( 29644062 )
2018
14
Cefazolin-Related Acute Interstitial Nephritis with Associated Nephrotic-Range Proteinuria: A Case Report. ( 29633042 )
2018
15
Clinical Manifestations and Outcomes of Fluoroquinolone-Related Acute Interstitial Nephritis. ( 29157532 )
2018
16
A Case of SjAPgren's Syndrome Complicated with Interstitial Nephritis and Delayed Onset Autoimmune Hepatitis. ( 29731495 )
2018
17
Mott cell interstitial nephritis revealing WaldenstrAPm macroglobulinaemia. ( 29629483 )
2018
18
Acute Interstitial Nephritis Induced by Citrullus Colocynthis. ( 29038395 )
2017
19
A case report of zinc phosphide poisoning: complicated by acute renal failure and tubulo interstitial nephritis. ( 28545504 )
2017
20
Acute granulomatous interstitial nephritis and acute rejection in a kidney transplant recipient after zoledronic acid therapy - a case report and review of the literature. ( 28655390 )
2017
21
A case of acute kidney injury caused by granulomatous interstitial nephritis associated with sarcoidosis. ( 29181823 )
2017
22
Granulomatous interstitial nephritis due to chronic lymphocytic leukemia: a case report. ( 29197349 )
2017
23
IgG4-Related Disease Manifesting as Interstitial Nephritis Accompanied by Hypophysitis. ( 28552902 )
2017
24
A Case Report of Acute Renal Failure as a Result of Light-Chain-Mediated Acute Tubular Interstitial Nephritis in a 30-Year-Old Combat Veteran. ( 29087890 )
2017
25
Acute Interstitial Nephritis Associated with Sofosbuvir and Daclatasvir. ( 28706960 )
2017
26
The increasing rates of acute interstitial nephritis in Australia: a single centre case series. ( 29089041 )
2017
27
Drug-Induced Acute Interstitial Nephritis. ( 28893923 )
2017
28
Novel oral anticoagulant and kidney injury: apixaban-related acute interstitial nephritis. ( 28847995 )
2017
29
Clinical profile and outcome of patients with biopsy-proven acute interstitial nephritis in Cape Town: a 10-year reviewa8c. ( 28438256 )
2017
30
Severe Acute Interstitial Nephritis: Response to Therapy With AntithymocyteA Globulin. ( 29142951 )
2017
31
Case 6: Skin Discoloration, Methemoglobinemia, and Acute Interstitial Nephritis in a 15-year-old Girl. ( 28765205 )
2017
32
Acute interstitial nephritis and DRESS syndrome without eosinophilia associated with cefepime. ( 28775112 )
2017
33
Alendronate sodium-induced interstitial nephritis. ( 29105273 )
2017
34
Cyclooxygenase-2 inhibitor-induced acute interstitial nephritis. ( 28536229 )
2017
35
Acute kidney injury with granulomatous interstitial nephritis and vasculitis revealing sarcoidosis. ( 28937078 )
2017
36
Acute interstitial nephritis after sequential ipilumumab - nivolumab therapy of metastatic melanoma. ( 28716106 )
2017
37
Monoclonal gammopathy of renal significance presenting as monotypic plasma cell interstitial nephritis in two patients with SjAPgren's syndrome. ( 29147924 )
2017
38
AJKD Atlas of Renal Pathology: Chronic Interstitial Nephritis. ( 28646984 )
2017
39
Silent Acute Interstitial Nephritis: Suspicion Is the Key to Diagnosis. ( 29203249 )
2017
40
Proton Pump Inhibitor and H2 Blocker-Associated Acute Interstitial Nephritis in a Renal Allograft. ( 29023281 )
2017
41
Acute Ciprofloxacin-Induced Crystal Nephropathy with Granulomatous Interstitial Nephritis. ( 28553048 )
2017
42
Allergic Interstitial Nephritis Masquerading as Pyelonephritis in a Pediatric Patient With Crohn Disease. ( 28644363 )
2017
43
Combination Cyclophosphamide/Glucocorticoids Provide Better Tolerability and Outcomes versus Glucocorticoids Alone in Patients with Sjogren's Associated Chronic Interstitial Nephritis. ( 29241210 )
2017
44
Sunitinib-Induced Acute Interstitial Nephritis in a Thrombocytopenic Renal Cell Cancer Patient. ( 29359059 )
2017
45
Infection associated acute interstitial nephritis; a case report. ( 28491853 )
2017
46
Interstitial nephritis in melanoma patients secondary to PD-1 checkpoint inhibitor. ( 28105370 )
2017
47
Acute interstitial nephritis in the south of Iran; an observational study. ( 28975105 )
2017
48
Undiagnosed renal sarcoidosis in a patient with chronic interstitial nephritis. ( 28875342 )
2017
49
Urine Eosinophils for Acute Interstitial Nephritis. ( 28459905 )
2017
50
Effective Treatment With Everolimus for Recurrent Granulomatous Interstitial Nephritis in a Renal Transplant Recipient: A Case Report. ( 27234775 )
2016

Variations for Interstitial Nephritis

Expression for Interstitial Nephritis

Search GEO for disease gene expression data for Interstitial Nephritis.

Pathways for Interstitial Nephritis

GO Terms for Interstitial Nephritis

Cellular components related to Interstitial Nephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.17 ACE AGT ALB APRT CRP REN

Biological processes related to Interstitial Nephritis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 kidney development GO:0001822 9.58 ACE AGT REN
2 regulation of blood pressure GO:0008217 9.54 ACE AGT REN
3 positive regulation of protein tyrosine kinase activity GO:0061098 9.51 ACE AGT
4 blood vessel remodeling GO:0001974 9.49 ACE AGT
5 regulation of vasoconstriction GO:0019229 9.48 ACE AGT
6 positive regulation of superoxide anion generation GO:0032930 9.46 AGT CRP
7 amyloid-beta metabolic process GO:0050435 9.43 ACE REN
8 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9.32 ACE AGT
9 renin-angiotensin regulation of aldosterone production GO:0002018 9.26 AGT REN
10 regulation of blood volume by renin-angiotensin GO:0002016 9.16 AGT REN
11 regulation of renal output by angiotensin GO:0002019 8.96 ACE AGT
12 angiotensin maturation GO:0002003 8.8 ACE AGT REN

Sources for Interstitial Nephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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