MCID: INT012
MIFTS: 23

Interval Angle-Closure Glaucoma

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Interval Angle-Closure Glaucoma

MalaCards integrated aliases for Interval Angle-Closure Glaucoma:

Name: Interval Angle-Closure Glaucoma 12 15
Intermittent Angle-Closure Glaucoma 12 70
Angle-Closure Glaucoma, Subacute 12
Prodromal Angle Closure Glaucoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13549
ICD9CM 34 365.21
SNOMED-CT 67 65460003
ICD10 32 H40.23
UMLS 70 C0154945

Summaries for Interval Angle-Closure Glaucoma

Disease Ontology : 12 A primary angle-closure glaucoma characterized by acute closure of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes suddenly inappropriately elevated threatening optic nerve damage and visual field loss; but that typically resolves spontaneously after several hours, even though it may recur. Interval angle-closure glaucoma has symptom sudden pain, redness, headache, and blurry vision with haloes around lights that resolves spontaneously. Interval angle-closure glaucoma can be caused by exacerbation of chronic primary angle-closure glaucoma, typically by a medication or state that dilates the eyes and thus narrows the anterior chamber angle, blocking any aqueous outflow.

MalaCards based summary : Interval Angle-Closure Glaucoma, also known as intermittent angle-closure glaucoma, is related to migraine with or without aura 1 and intraocular pressure quantitative trait locus, and has symptoms including sudden pain An important gene associated with Interval Angle-Closure Glaucoma is RCVRN (Recoverin). Affiliated tissues include eye, brain and retina.

Related Diseases for Interval Angle-Closure Glaucoma

Diseases related to Interval Angle-Closure Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 82)
# Related Disease Score Top Affiliating Genes
1 migraine with or without aura 1 29.4 TAC1 MAOB KNG1 CRP
2 intraocular pressure quantitative trait locus 10.3
3 nonsyndromic retinitis pigmentosa 10.2 BEST1 ABCA4
4 chorioretinal scar 10.2 BEST1 ABCA4
5 macular degeneration, age-related, 6 10.2 BEST1 ABCA4
6 macular degeneration, age-related, 4 10.2 BEST1 ABCA4
7 peripheral retinal degeneration 10.2 BEST1 ABCA4
8 basal laminar drusen 10.2 BEST1 ABCA4
9 isolated macular dystrophy 10.2 BEST1 ABCA4
10 vitreoretinochoroidopathy 10.2 BEST1 ABCA4
11 scotoma 10.2 RCVRN ABCA4
12 retinal drusen 10.2 BEST1 ABCA4
13 bestrophinopathy, autosomal recessive 10.2 BEST1 ABCA4
14 hereditary retinal dystrophy 10.2 BEST1 ABCA4
15 choroid disease 10.1 BEST1 ABCA4
16 cancer-associated retinopathy 10.1 RCVRN ENO1
17 gyrate atrophy of choroid and retina 10.1 BEST1 ABCA4
18 doyne honeycomb retinal dystrophy 10.1 BEST1 ABCA4
19 acute closed-angle glaucoma 10.1
20 primary angle-closure glaucoma 10.1
21 choroideremia 10.1 BEST1 ABCA4
22 retinoschisis 1, x-linked, juvenile 10.1 BEST1 ABCA4
23 late-onset retinal degeneration 10.1 BEST1 ABCA4
24 serotonin syndrome 10.1 TAC1 MAOB
25 chorioretinitis 10.0 CRP ABCA4
26 stargardt disease 1 10.0 BEST1 ABCA4
27 atypical depressive disorder 10.0 MAOB CRP
28 macular dystrophy, dominant cystoid 10.0 RCVRN BEST1 ABCA4
29 optic nerve hypoplasia, bilateral 10.0 RCVRN BEST1 ABCA4
30 cone-rod dystrophy 6 10.0 BEST1 ABCA4
31 degeneration of macula and posterior pole 10.0 RCVRN BEST1 ABCA4
32 eye degenerative disease 10.0 RCVRN BEST1 ABCA4
33 neurogenic arthropathy 10.0 TAC1 CRP
34 plantar fasciitis 10.0 TAC1 CRP
35 arachnoiditis 10.0 TAC1 CRP
36 paralytic ileus 10.0 TAC1 CRP
37 retinal degeneration 10.0 RCVRN BEST1 ABCA4
38 autoimmune vasculitis 10.0 ENO1 CRP
39 spondylolisthesis 10.0 TAC1 CRP
40 mononeuropathy 10.0 TAC1 CRP
41 tendinitis 10.0 TAC1 CRP
42 congenital stationary night blindness 10.0 RCVRN BEST1 ABCA4
43 nerve compression syndrome 10.0 TAC1 CRP
44 relapsing polychondritis 10.0 ENO1 CRP
45 aspiration pneumonia 9.9 TAC1 CRP
46 vitelliform macular dystrophy 9.9 BEST1 ABCA4
47 chronic spontaneous urticaria 9.9 TAC1 CRP
48 neurogenic bladder 9.9 TAC1 CRP
49 nose disease 9.9 TAC1 CRP
50 meningoencephalitis 9.9 TAC1 CRP

Graphical network of the top 20 diseases related to Interval Angle-Closure Glaucoma:



Diseases related to Interval Angle-Closure Glaucoma

Symptoms & Phenotypes for Interval Angle-Closure Glaucoma

Symptoms:

12
  • sudden pain

Drugs & Therapeutics for Interval Angle-Closure Glaucoma

Search Clinical Trials , NIH Clinical Center for Interval Angle-Closure Glaucoma

Genetic Tests for Interval Angle-Closure Glaucoma

Anatomical Context for Interval Angle-Closure Glaucoma

MalaCards organs/tissues related to Interval Angle-Closure Glaucoma:

40
Eye, Brain, Retina

Publications for Interval Angle-Closure Glaucoma

Articles related to Interval Angle-Closure Glaucoma:

(show all 11)
# Title Authors PMID Year
1
Headaches attributed to visual disturbances. 61
26017519 2015
2
Ocular and orbital pain for the headache specialist. 61
21128023 2011
3
Iridoschisis: case report and review of the literature. 61
21499560 2011
4
Persistent unilateral mydriasis and headache. 61
21686386 2009
5
Management of intermittent angle closure glaucoma with Nd: YAG laser iridotomy as a primary procedure. 61
17125635 2006
6
Intermittent angle-closure glaucoma in the presence of a white eye, posing as retinal migraine. 61
16886947 2006
7
Unusual visual disturbance following laser peripheral iridotomy for intermittent angle closure glaucoma. 61
16228219 2006
8
Intermittent angle-closure glaucoma in the presence of a white eye, posing as retinal migraine. 61
16033388 2005
9
Uveal effusion and angle-closure glaucoma in primary pulmonary hypertension. 61
12719080 2003
10
Adie's tonic pupil-induced angle-closure glaucoma. 61
11901294 2002
11
Clinical findings in Brown-McLean syndrome. 61
8506907 1993

Variations for Interval Angle-Closure Glaucoma

Expression for Interval Angle-Closure Glaucoma

Search GEO for disease gene expression data for Interval Angle-Closure Glaucoma.

Pathways for Interval Angle-Closure Glaucoma

GO Terms for Interval Angle-Closure Glaucoma

Cellular components related to Interval Angle-Closure Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 photoreceptor outer segment GO:0001750 8.62 RCVRN ABCA4

Biological processes related to Interval Angle-Closure Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.33 TAC1 KNG1 CRP
2 regulation of calcium ion transport GO:0051924 8.96 RCVRN BEST1
3 visual perception GO:0007601 8.8 RCVRN BEST1 ABCA4

Sources for Interval Angle-Closure Glaucoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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