MCID: INT012
MIFTS: 20

Interval Angle-Closure Glaucoma

Categories: Eye diseases

Aliases & Classifications for Interval Angle-Closure Glaucoma

MalaCards integrated aliases for Interval Angle-Closure Glaucoma:

Name: Interval Angle-Closure Glaucoma 12 15
Intermittent Angle-Closure Glaucoma 12 73
Angle-Closure Glaucoma, Subacute 12
Prodromal Angle Closure Glaucoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13549
ICD10 33 H40.23
ICD9CM 35 365.21
SNOMED-CT 68 65460003
UMLS 73 C0154945

Summaries for Interval Angle-Closure Glaucoma

MalaCards based summary : Interval Angle-Closure Glaucoma, also known as intermittent angle-closure glaucoma, is related to adult oligodendroglioma and enchondroma. An important gene associated with Interval Angle-Closure Glaucoma is IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial), and among its related pathways/superpathways are Glucose / Energy Metabolism and Carbon metabolism. Affiliated tissues include eye.

Related Diseases for Interval Angle-Closure Glaucoma

Diseases related to Interval Angle-Closure Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
# Related Disease Score Top Affiliating Genes
1 adult oligodendroglioma 9.8 IDH1 IDH2
2 enchondroma 9.8 IDH1 IDH2
3 intracranial chondrosarcoma 9.8 IDH1 IDH2
4 cytogenetically normal acute myeloid leukemia 9.8 IDH1 IDH2
5 chondroblastic osteosarcoma 9.8 IDH1 IDH2
6 intraductal papilloma 9.8 IDH1 IDH2
7 multiple enchondromatosis, maffucci type 9.8 IDH1 IDH2
8 pilocytic astrocytoma of cerebellum 9.8 IDH1 IDH2
9 spindle cell hemangioma 9.8 IDH1 IDH2
10 glioma susceptibility 1 9.8 IDH1 IDH2
11 periosteal chondrosarcoma 9.8 IDH1 IDH2
12 adult astrocytic tumour 9.8 IDH1 IDH2
13 fibrillary astrocytoma 9.8 IDH1 IDH2
14 undifferentiated pleomorphic sarcoma 9.8 IDH1 IDH2
15 drug-induced mental disorder 9.8 IDH1 IDH2
16 drug psychosis 9.8 IDH1 IDH2
17 diffuse infiltrative lymphocytosis syndrome 9.7 IDH1 IDH2
18 2-hydroxyglutaric aciduria 9.7 IDH1 IDH2
19 brain stem glioma 9.7 IDH1 IDH2
20 breast papillary carcinoma 9.7 IDH1 IDH2
21 d-2-hydroxyglutaric aciduria 1 9.7 IDH1 IDH2
22 enchondromatosis, multiple, ollier type 9.7 IDH1 IDH2
23 bile duct adenocarcinoma 9.7 IDH1 IDH2
24 intrahepatic cholangiocarcinoma 9.7 IDH1 IDH2
25 oligodendroglioma 9.6 IDH1 IDH2
26 chondrosarcoma 9.6 IDH1 IDH2
27 essential thrombocythemia 9.6 IDH1 IDH2
28 myelofibrosis 9.6 IDH1 IDH2
29 myeloma, multiple 9.6 IDH1 IDH2
30 brain cancer 9.5 IDH1 IDH2
31 cholangiocarcinoma 9.5 IDH1 IDH2
32 glioma 9.4 IDH1 IDH2
33 leukemia, acute myeloid 9.3 IDH1 IDH2
34 myelodysplastic syndrome 9.2 IDH1 IDH2
35 glioblastoma 9.0 IDH1 IDH2

Graphical network of the top 20 diseases related to Interval Angle-Closure Glaucoma:



Diseases related to Interval Angle-Closure Glaucoma

Symptoms & Phenotypes for Interval Angle-Closure Glaucoma

Drugs & Therapeutics for Interval Angle-Closure Glaucoma

Search Clinical Trials , NIH Clinical Center for Interval Angle-Closure Glaucoma

Genetic Tests for Interval Angle-Closure Glaucoma

Anatomical Context for Interval Angle-Closure Glaucoma

MalaCards organs/tissues related to Interval Angle-Closure Glaucoma:

41
Eye

Publications for Interval Angle-Closure Glaucoma

Variations for Interval Angle-Closure Glaucoma

Expression for Interval Angle-Closure Glaucoma

Search GEO for disease gene expression data for Interval Angle-Closure Glaucoma.

Pathways for Interval Angle-Closure Glaucoma

GO Terms for Interval Angle-Closure Glaucoma

Cellular components related to Interval Angle-Closure Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peroxisome GO:0005777 8.62 IDH1 IDH2

Biological processes related to Interval Angle-Closure Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tricarboxylic acid cycle GO:0006099 9.26 IDH1 IDH2
2 2-oxoglutarate metabolic process GO:0006103 9.16 IDH1 IDH2
3 isocitrate metabolic process GO:0006102 8.96 IDH1 IDH2
4 glyoxylate cycle GO:0006097 8.62 IDH1 IDH2

Molecular functions related to Interval Angle-Closure Glaucoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.37 IDH1 IDH2
2 magnesium ion binding GO:0000287 9.32 IDH1 IDH2
3 NAD binding GO:0051287 9.26 IDH1 IDH2
4 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 9.16 IDH1 IDH2
5 isocitrate dehydrogenase activity GO:0004448 8.96 IDH1 IDH2
6 isocitrate dehydrogenase (NADP+) activity GO:0004450 8.62 IDH1 IDH2

Sources for Interval Angle-Closure Glaucoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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