MCID: INT050
MIFTS: 22

Intestinal Impaction

Categories: Gastrointestinal diseases
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Aliases & Classifications for Intestinal Impaction

MalaCards integrated aliases for Intestinal Impaction:

Name: Intestinal Impaction 11 14

Classifications:



External Ids:

Disease Ontology 11 DOID:8448
ICD9CM 34 560.39
SNOMED-CT 68 197540000
ICD10 31 K56.4
UMLS 71 C0029640

Summaries for Intestinal Impaction

MalaCards based summary: Intestinal Impaction is related to complex partial epilepsy and thelaziasis. An important gene associated with Intestinal Impaction is SLC4A5 (Solute Carrier Family 4 Member 5), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Proximal tubule transport. Related phenotypes are homeostasis/metabolism and renal/urinary system

Related Diseases for Intestinal Impaction

Graphical network of the top 20 diseases related to Intestinal Impaction:



Diseases related to Intestinal Impaction

Symptoms & Phenotypes for Intestinal Impaction

MGI Mouse Phenotypes related to Intestinal Impaction:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.56 AHCYL1 CLCN4 SLC26A3 SLC4A4 SLC4A5 SLC4A7
2 renal/urinary system MP:0005367 9.55 CLCN4 SLC4A4 SLC4A5 SLC9A3 TAGLN
3 digestive/alimentary MP:0005381 9.02 AHCYL1 SLC26A3 SLC4A4 SLC9A3 TAGLN

Drugs & Therapeutics for Intestinal Impaction

Search Clinical Trials, NIH Clinical Center for Intestinal Impaction

Genetic Tests for Intestinal Impaction

Anatomical Context for Intestinal Impaction

Publications for Intestinal Impaction

Articles related to Intestinal Impaction:

(show all 14)
# Title Authors PMID Year
1
Toxocara vitulorum intestinal impaction in male White Fulani calves: a case report from Nigeria. 62
31749530 2019
2
Mortality associated with ingestion of sea urchins in loggerhead sea turtles (Caretta caretta): A case series. 62
31442294 2019
3
Biliary ileus: case report. 62
28732000 2017
4
Healthcare Utilization and Spending for Constipation in Children With Versus Without Complex Chronic Conditions. 62
27070656 2017
5
Biphasic appearance of corticated and decorticated ascarid egg shedding in untreated horse foals. 62
26391818 2015
6
Prevalence and risk of developing comorbid conditions in patients with chronic constipation. 62
25215427 2014
7
Use of health care resources and cost of care for adults with constipation. 62
17625982 2007
8
An adenovirus associated with intestinal impaction and mortality of male common eiders (Somateria mollissima) in the Baltic Sea. 62
12685074 2003
9
Analysis of hemostasis in horses with colic. 62
8407538 1993
10
Feeding and digestive problems in horses. Physiologic responses to a concentrated meal. 62
2202501 1990
11
Ascarids. Recent advances. 62
3527375 1986
12
A method of electro-acupuncture treatment for equine intestinal impaction. 62
7345923 1981
13
Amitraz induced large intestinal impaction in the horse. 62
543829 1979
14
The use of cholinergic drugs in treating intestinal impaction in the horse. 62
4483119 1972

Variations for Intestinal Impaction

Expression for Intestinal Impaction

Search GEO for disease gene expression data for Intestinal Impaction.

Pathways for Intestinal Impaction

Pathways related to Intestinal Impaction according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.24 SLC9A3 SLC4A7 SLC4A5 SLC4A4 SLC26A3 CLCN4
2 10.71 SLC9A3 SLC4A4

GO Terms for Intestinal Impaction

Cellular components related to Intestinal Impaction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 basolateral plasma membrane GO:0016323 9.43 SLC4A7 SLC4A5 SLC4A4
2 apical plasma membrane GO:0016324 9.32 SLC9A3 SLC4A7 SLC4A5 SLC26A3 AHCYL1

Biological processes related to Intestinal Impaction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium ion transmembrane transport GO:0035725 10 SLC9A3 SLC4A7 SLC4A5 SLC4A4
2 transmembrane transport GO:0055085 9.97 CLCN4 SLC26A3 SLC4A4 SLC4A5 SLC4A7 SLC9A3
3 inorganic anion transport GO:0015698 9.95 SLC4A7 SLC4A5 SLC4A4
4 anion transmembrane transport GO:0098656 9.91 SLC4A7 SLC4A5 SLC4A4
5 ion transport GO:0006811 9.86 SLC9A3 SLC4A7 SLC4A5 SLC4A4 SLC26A3 CLCN4
6 ion homeostasis GO:0050801 9.85 SLC4A7 SLC4A5 SLC4A4
7 sodium ion transport GO:0006814 9.8 SLC9A3 SLC4A7 SLC4A5 SLC4A4
8 regulation of intracellular pH GO:0051453 9.76 SLC9A3 SLC4A7 SLC4A5 SLC4A4
9 bicarbonate transport GO:0015701 9.56 SLC4A7 SLC4A5 SLC4A4 SLC26A3
10 anion transport GO:0006820 9.02 SLC4A7 SLC4A5 SLC4A4 SLC26A3

Molecular functions related to Intestinal Impaction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane transporter activity GO:0022857 9.88 SLC4A7 SLC4A5 SLC4A4
2 antiporter activity GO:0015297 9.56 SLC9A3 SLC26A3 CLCN4
3 solute:proton antiporter activity GO:0015299 9.5 SLC9A3 CLCN4
4 sodium:bicarbonate symporter activity GO:0008510 9.43 SLC4A7 SLC4A5 SLC4A4
5 triplet codon-amino acid adaptor activity GO:0030533 9.37 MT-TY MT-TN
6 anion transmembrane transporter activity GO:0008509 9.33 SLC4A7 SLC4A5 SLC4A4
7 solute:inorganic anion antiporter activity GO:0005452 9.23 SLC4A7 SLC4A5 SLC4A4 SLC26A3

Sources for Intestinal Impaction

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 24-Oct-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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