MCID: INT071
MIFTS: 45

Intestinal Perforation

Categories: Gastrointestinal diseases

Aliases & Classifications for Intestinal Perforation

MalaCards integrated aliases for Intestinal Perforation:

Name: Intestinal Perforation 12 44 15 17 72
Perforation of Intestine 12 33

Classifications:



External Ids:

Disease Ontology 12 DOID:2074
ICD9CM 35 569.83
MeSH 44 D007416
NCIt 50 C39611
SNOMED-CT 68 56905009
ICD10 33 K63.1
UMLS 72 C0021845

Summaries for Intestinal Perforation

MalaCards based summary : Intestinal Perforation, also known as perforation of intestine, is related to intestinal obstruction and pleomorphic carcinoma. An important gene associated with Intestinal Perforation is PRODH (Proline Dehydrogenase 1), and among its related pathways/superpathways are Arginine and proline metabolism and Doxorubicin Pathway, Pharmacokinetics. The drugs Clavulanate and Meropenem have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and liver, and related phenotypes are homeostasis/metabolism and digestive/alimentary

Related Diseases for Intestinal Perforation

Diseases related to Intestinal Perforation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 319)
# Related Disease Score Top Affiliating Genes
1 intestinal obstruction 30.8 NOD2 KRT7
2 pleomorphic carcinoma 30.6 NKX2-1 KRT7
3 cystic teratoma 30.2 NKX2-1 KRT7
4 adenosquamous carcinoma 29.8 NKX2-1 KRT7
5 spondyloarthropathy 1 28.6 NOD2 CRP
6 perinatal intestinal perforation 12.6
7 hirschsprung disease 1 11.7
8 behcet syndrome 11.6
9 enterocolitis 10.7
10 peritonitis 10.7
11 perinatal necrotizing enterocolitis 10.7
12 typhoid fever 10.6
13 ovarian germ cell teratoma 10.5 NKX2-1 KRT7
14 solid adenocarcinoma with mucin production 10.5 NKX2-1 KRT7
15 small cell carcinoma 10.5 NKX2-1 KRT7
16 small cell carcinoma of the bladder 10.5 NKX2-1 KRT7
17 lung acinar adenocarcinoma 10.5 NKX2-1 KRT7
18 ovarian germ cell cancer 10.5 NKX2-1 KRT7
19 papillary adenoma 10.5 NKX2-1 KRT7
20 papillary serous adenocarcinoma 10.5 NKX2-1 KRT7
21 pulmonary sclerosing hemangioma 10.5 NKX2-1 KRT7
22 sclerosing hemangioma 10.5 NKX2-1 KRT7
23 alveoli adenoma 10.5 NKX2-1 KRT7
24 mucinous bronchioloalveolar adenocarcinoma 10.5 NKX2-1 KRT7
25 atypical choroid plexus papilloma 10.5 NKX2-1 KRT7
26 ovarian cystic teratoma 10.5 NKX2-1 KRT7
27 horseshoe kidney 10.5 NKX2-1 KRT7
28 hidradenocarcinoma 10.4 NKX2-1 KRT7
29 large cell neuroendocrine carcinoma 10.4 NKX2-1 KRT7
30 papillary adenocarcinoma 10.4 NKX2-1 KRT7
31 mucinous adenocarcinoma 10.4 NKX2-1 KRT7
32 bronchiolo-alveolar adenocarcinoma 10.4 NKX2-1 KRT7
33 vasculitis 10.3
34 crohn's disease 10.3
35 dyskinetic cerebral palsy 10.3 PTS NKX2-1
36 ileus 10.3
37 lung benign neoplasm 10.3 NKX2-1 KRT7
38 tetrahydrobiopterin deficiency 10.3 PTS NOS1
39 patent ductus arteriosus 1 10.3
40 cavernous hemangioma 10.3 NKX2-1 KRT7
41 inguinal hernia 10.2
42 toxic shock syndrome 10.2
43 appendicitis 10.2
44 intestinal tuberculosis 10.2
45 purpura 10.2
46 diverticulitis 10.2
47 polyarteritis nodosa 10.2
48 cytomegalovirus infection 10.2
49 intussusception 10.1
50 miliary tuberculosis 10.1

Comorbidity relations with Intestinal Perforation via Phenotypic Disease Network (PDN): (show all 15)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Vascular Insufficiency of Intestine
Cecal Benign Neoplasm Colorectal Cancer
Deficiency Anemia Familial Atrial Fibrillation
Heart Disease Intestinal Obstruction
Paralytic Ileus Peritonitis
Protein-Energy Malnutrition Rectosigmoid Junction Neoplasm
Respiratory Failure

Graphical network of the top 20 diseases related to Intestinal Perforation:



Diseases related to Intestinal Perforation

Symptoms & Phenotypes for Intestinal Perforation

MGI Mouse Phenotypes related to Intestinal Perforation:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.65 COL3A1 CRP KRT7 NFKB1 NKX2-1 NOD2
2 digestive/alimentary MP:0005381 9.63 COL3A1 NFKB1 NKX2-1 NOD2 NOS1 PTS
3 respiratory system MP:0005388 9.02 COL3A1 NFKB1 NKX2-1 NOS1 PRDM6

Drugs & Therapeutics for Intestinal Perforation

Drugs for Intestinal Perforation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 53)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clavulanate Approved, Vet_approved Phase 3 58001-44-8 5280980
2
Meropenem Approved, Investigational Phase 3 119478-56-7, 96036-03-2 64778 441130
3
Amoxicillin Approved, Vet_approved Phase 3 26787-78-0 33613
4
Doripenem Approved, Investigational Phase 3 148016-81-3 73303
5 Pharmaceutical Solutions Phase 2, Phase 3
6 Anti-Infective Agents Phase 3
7 Anti-Bacterial Agents Phase 3
8 Amoxicillin-Potassium Clavulanate Combination Phase 3
9 beta-Lactamase Inhibitors Phase 3
10
Cisplatin Approved Phase 2 15663-27-1 84093 441203 2767
11
Docetaxel Approved, Investigational Phase 2 114977-28-5 148124
12
Acetaminophen Approved Phase 2 103-90-2 1983
13
Indomethacin Approved, Investigational Phase 2 53-86-1 3715
14
Mupirocin Approved, Investigational, Vet_approved Phase 2 12650-69-0 446596
15
Petrolatum Approved, Investigational Phase 2 8009-03-8
16 Tubulin Modulators Phase 2
17 Antimitotic Agents Phase 2
18 Fat Emulsions, Intravenous Phase 2
19 Parenteral Nutrition Solutions Phase 2
20 Soy Bean Phase 2
21 Soybean oil, phospholipid emulsion Phase 2
22 Dermatologic Agents Phase 2
23 Emollients Phase 2
24 Antibodies Phase 1
25 Immunoglobulins Phase 1
26 Antibodies, Monoclonal Phase 1
27
Bupivacaine Approved, Investigational 2180-92-9, 38396-39-3 2474
28
Lidocaine Approved, Vet_approved 137-58-6 3676
29
Racepinephrine Approved 329-65-7 838
30
Epinephrine Approved, Vet_approved 51-43-4 5816
31
Ibuprofen Approved 15687-27-1 3672
32 Anesthetics, Local
33 Central Nervous System Depressants
34 Epinephryl borate
35 Anesthetics
36 Respiratory System Agents
37 Hormones
38 glucocorticoids
39 Hormone Antagonists
40 Anti-Asthmatic Agents
41 Hormones, Hormone Substitutes, and Hormone Antagonists
42
Beclomethasone 4419-39-0 20469
43 Lactoferrin
44 Antibiotics, Antitubercular
45 Cola
46 Liver Extracts
47 Peripheral Nervous System Agents
48 Analgesics
49 Anti-Inflammatory Agents
50 Analgesics, Non-Narcotic

Interventional clinical trials:

(show all 49)
# Name Status NCT ID Phase Drugs
1 Randomized Evaluation of the Use of Plastic Bags to Prevent Neonatal Hypothermia in Developing Countries-Part IV Completed NCT01604447 Phase 4
2 Effects of Recto-colic Enemas of Butyrate on the Digestive Disorders of Very Low Birth Weight Preterms <1250 Grams. Clinical Trial Prospective, Monocentric, Randomized in Double-blinded. Terminated NCT01536483 Phase 2, Phase 3 Butyrate enemas
3 A Prospective, Randomized, Double-Blind, Multicenter Study to Establish the Safety and Tolerability of Doripenem Compared With Meropenem in Hospitalized Children With Complicated Intra-Abdominal Infections Terminated NCT01110382 Phase 3 Doripenem;Meropenem placebo;Meropenem;Doripenem placebo;Amoxicillin/clavulanate potassium
4 Phase II Study of Salvage Therapy With Sunitinib,Docetaxel and Platinum on Metastatic or Unresectable Non Small Cell Lung Cancer Unknown status NCT01019798 Phase 2 sunitinib, docetaxel, cisplatin
5 Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus in Preterm infants-a Multicenter Trial Completed NCT01958320 Phase 2 NSAID
6 Early Supplementation of Enteral Microlipid With and Without Fish Oil in Premature Infants With Enterostomies Completed NCT01674478 Phase 2
7 Randomized Controlled Trial of Mupirocin to Reduce Staphylococcus Aureus Colonization in Infants Hospitalized in a Neonatal Intensive Care Unit Recruiting NCT02967432 Phase 2 Mupirocin Topical Ointment;Petroleum Jelly
8 A Phase II Trial of Sunitinib and Nivolumab for KIT-mutated Advanced Melanoma Withdrawn NCT02400385 Phase 2 sunitinib;nivolumab
9 An Open-Label Trial of Tocilizumab in Schizophrenia Completed NCT01696929 Phase 1 Tocilizumab
10 A Randomized Controlled Trial of Adjunctive Tocilizumab in Schizophrenia Recruiting NCT02874573 Phase 1 Tocilizumab;Normal saline
11 Immunoreactive Trypsinogen in Infants With Intestinal Perforation Unknown status NCT01530828
12 Ultrasound Guided Transversus Abdominis Plane(TAP) Block in Intensive Care Unit(ICU) for Postoperative Analgesia After Open Colon Resection: a Double Blind Randomized Controlled Trial Unknown status NCT03198338 0.25% Bupivacaine, 0.5mL/kg;Normal Saline
13 Probiotics Supplementation and Length of Hospital Stay in Neonates With Gastrointestinal Surgery Unknown status NCT03266315
14 Procalcitonin Ratio's Impact on the Decision Upon On-demand Relaparotomy in Septic Peritonitis Completed NCT01768936
15 Observational Study of Surgical Treatment of Necrotizing Enterocolotis or Isolated Intestinal Perforation Completed NCT01223261
16 Evaluation of the Ability to Detect Bowel Gas During Laparoscopic Surgery Completed NCT02679118
17 A Multi-center Randomized Trial of Laparotomy vs. Drainage as the Initial Surgical Therapy for ELBW Infants With Necrotizing Enterocolitis (NEC) or Isolated Intestinal Perforation (IP): Outcomes at 18-22 Months Adjusted Age Completed NCT01029353
18 Effect of Continuous Thoracic Epidural Analgesia on Gut Motility Following Emergency Laparotomy for Intestinal Perforation Under General Anesthesia Completed NCT03145389
19 Early Supplementation of Enteral Lipid With Combination of Microlipid and Fish Oil in Infants With Enterostomy Completed NCT01306838 Early Phase 1
20 Factors Associated With Relapses in Patients Suffering From Clostridium Difficile Infection: Immune Response Completed NCT02440438
21 Observational Study of Relationship Between Intra-abdominal Hypertension and Severe Sepsis in Surgical Patients Completed NCT01784458
22 Prediction of Feeding Problems in Prostaglandin-dependent Prematurely Born Infants With Congenital Heart Disease Completed NCT01126372
23 Splanchnic Oxygenation and Perfusion Response to Enteral Feeds in Preterm Infants With Abnormal Antenatal Doppler: Pattern Assessment and Correlation With Feeding Intolerance Completed NCT02971566
24 Evaluation of Post-Discharge Growth and Development of Infants Who Received Donor Human Milk Products in the NICU Completed NCT01483079
25 Effect of Patent Ductus Arteriosus on Splanchnic Oxygenation at Enteral Feeding Introduction in Preterm Infants Completed NCT03723889
26 Splanchnic Tissue Oxygenation During Enteral Feedings in Anemic Premature Infants at Risk for Necrotizing Enterocolitis Completed NCT01735578
27 Intestinal Microbiota and Short Term Outcomes in Very Low Birth Weight Infants Fed Primarily Donor Human Milk Compared to Infants Fed Primarily Mother's Own Milk Completed NCT02573779
28 A Dose-Ranging Study to Assess the Effect of Inhaled Corticosteroids in Ventilated Preterm Neonates Completed NCT03503994 Inhaled Beclomethasone Dipropionate Monohydrate
29 Prospective Registry The Treatment Of Upper And Lower Intestinal Anastomotic Leaks And Perforations Recruiting NCT02477930
30 Proximal Remnant Intestinal Colonization in Newborn Infants With Enterostomy: a Longitudinal Study Recruiting NCT03340259
31 Pathophysiology of Perioperative Fluid Management in Patients Un-dergoing High Risk Emergency Laparotomy, a Prospective Descriptive Cohort Study Recruiting NCT03997721
32 Symptomatic Uncomplicated Diverticular Disease: a lactofErriN piLot studY Recruiting NCT03490279
33 A Randomized Multicenter Open-label Controlled Trial to Show That Mucous Fistula Refeeding Reduces the Time From Enterostomy Closure to Full Enteral Feeds (MUCous FIstula REfeeding ("MUC-FIRE") Trial) Recruiting NCT03469609
34 Standardised Perioperative Management of Patients Operated With Acute Abdominal Surgery in a High-risk Emergency Setting Recruiting NCT03549624
35 Extensively Hydrolyzed Liquid Human Milk Fortifier Versus Liquid Human Milk Fortifier With Supplemental Liquid Protein Recruiting NCT03001479
36 Tolerance of Early High Protein Nutrition of the Critically Ill: Comparison of a Protein-rich Enteral Formula With a Standardized High Carbohydrate Product on Total Calorie and Protein Intake Recruiting NCT02678325
37 Necrotizing Enterocolitis (NEC) & Platelet-Activating Factor (PAF)-Stimulated Protein Translation in Premature Infants Recruiting NCT00747851
38 Safeguarding the Brain of Our Smallest Children - an Investigator-initiated, Pragmatic, Open Label, Multinational Randomized Phase IIIclinical Trial Evaluating Treatment Based on Near-infrared Spectroscopy Monitoring Versus Treatment as Usual in Premature Infants Recruiting NCT03770741
39 Non-invasive Auxiliary Diagnosis of Colorectal Cancer and Advanced Adenoma by Detecting Cancer-specific Methylation Signatures in Plasma ctDNA Recruiting NCT03828396
40 Delayed Small-Bowel Anastomosis in Patients With Postoperative Peritonitis Due to Nontraumatic Small-Bowel Perforation and Anastomotic Leak: Cohort Study Active, not recruiting NCT03690687
41 Vacuum Assisted Closure Versus On-demand Relaparotomy in Patients With Fecal or Diffuse Peritonitis: A Multicenter Randomized Controlled Trial Not yet recruiting NCT03932461
42 The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery. Not yet recruiting NCT04020939 Indocyanine Green
43 Doppler Ultrasonography in Assessment of Graft Hemodynamics After Living-Donor Liver Transplantation in Al-Rajhi Liver Hospital Not yet recruiting NCT03893773
44 Continuous Versus Intermittent Bolus Feeding in Very Preterm Infants - Effects on Respiratory Morbidity: A Multicentre Randomised Controlled Clinical Trial Not yet recruiting NCT03961139
45 A Prospective Multicenter Randomized Controlled Clinical Trial to Compare the Method of Protective Diverting Loop Ileostomy With or Without the Support of a Plastic Rod Terminated NCT00959738
46 Timing of PDA Closure and Respiratory Outcome in Premature Infants Terminated NCT00802685 Early ibuprofen
47 Prospective Randomized Trial of Anterograde Single Balloon Versus Spirus Enteroscopy in Patients With Suspected Small Bowel Disease Terminated NCT01853241
48 Early Delivery in Fetal Gastroschisis: a Randomized Controlled Trial of Elective Early Delivery Versus Routine Obstetrical Care Terminated NCT01884324
49 Randomized Evaluation of the Use of Plastic Bags to Prevent Neonatal Hypothermia in Developing Countries-Part III Withdrawn NCT01604434

Search NIH Clinical Center for Intestinal Perforation

Cochrane evidence based reviews: intestinal perforation

Genetic Tests for Intestinal Perforation

Anatomical Context for Intestinal Perforation

MalaCards organs/tissues related to Intestinal Perforation:

41
Colon, Small Intestine, Liver, Lung, Bone, T Cells, Kidney

Publications for Intestinal Perforation

Articles related to Intestinal Perforation:

(show top 50) (show all 2102)
# Title Authors PMID Year
1
Surgical Outcomes in Patients with Abdominal Cocoon: Series of 15 Patients. 38
31011822 2019
2
Safety of Endoscopy in Heritable Connective Tissue Disorders. 38
31185005 2019
3
Intraperitoneal α-Emitting Radioimmunotherapy with 211At in Relapsed Ovarian Cancer: Long-Term Follow-up with Individual Absorbed Dose Estimations. 38
30683761 2019
4
Pseudoprogression presenting as intestinal perforation in non-small cell lung cancer treated with anti-PD-1: A case report. 38
31281646 2019
5
Dosing and Safety of Off-label Use of Caffeine Citrate in Premature Infants. 38
31101409 2019
6
Granulomatosis with polyangiitis with intestinal involvement successfully treated with rituximab and surgery. 38
31401575 2019
7
Synergistic effect of enteral nutrition on remission induction in a patient with penetrating Crohn disease: A case report. 38
31393390 2019
8
Efficacy and safety of systemic hydrocortisone for the prevention of bronchopulmonary dysplasia in preterm infants: a systematic review and meta-analysis. 38
31144162 2019
9
Methicillin-Resistant Staphylococcus aureus Meningitis from Transanal Migration of a Ventriculoperitoneal Shunt. 38
31402070 2019
10
Microbiological epidemiology of preservation fluids in transplanted kidney: a nationwide retrospective observational study. 38
31382016 2019
11
Fragility of Life: Recurrent Intestinal Perforation Due to Vascular Ehlers-Danlos Syndrome. 38
30656563 2019
12
Outcome and risk factors associated with perirenal subcapsular fluid collections in extremely preterm infants with acute kidney injury. 38
30715587 2019
13
Re-feeding versus discarding gastric residuals to improve growth in preterm infants. 38
31283000 2019
14
Complications associated with the current sequential pharmacological management of early postnatal hypotension in extremely premature infants. 38
31384186 2019
15
Intestinal Behçet's Disease with Primary Myelofibrosis Involving Trisomy 8. 38
31291615 2019
16
Pneumatosis intestinalis: cost paid for rheumatoid arthritis treatment. 38
31366614 2019
17
Early experiences with PD-1 inhibitor treatment of platinum resistant epithelial ovarian cancer. 38
31074244 2019
18
A multi-institutional experience in vascular Ehlers-Danlos syndrome diagnosis. 38
31353273 2019
19
Intestinal Perforation in Children as an Important Differential Diagnosis of Vascular Ehlers-Danlos Syndrome. 38
31324749 2019
20
[Chilaiditi sign and differential diagnosis with intestinal perforation]. 38
30755331 2019
21
Multicenter retrospective comparison of spontaneous intestinal perforation outcomes between primary peritoneal drain and primary laparotomy. 38
31383579 2019
22
Scrotal ulcerations in a newborn secondary to unnoticed prenatal intestinal perforation. 38
31273008 2019
23
Successful conservative treatment of intestinal perforation in VLBW and ELBW neonates: a single centre case series and review of the literature. 38
31345184 2019
24
Blowhole tangential cecostomy and transanal tube insertion for neonatal cecal perforation in a patient with Hirschsprung's disease in the earlier definitive operation era. 38
31292778 2019
25
What Do Saudi Children Ingest?: A 10-Year Retrospective Analysis of Ingested Foreign Bodies From a Tertiary Care Center. 38
31348207 2019
26
Complications of Long-Term Indwelling Transmural Double Pigtail Stent Placement for Symptomatic Peripancreatic Fluid Collections. 38
30725302 2019
27
Small bowel perforation secondary to foreign body ingestion mimicking acute appendicitis: Case report. 38
31348257 2019
28
Steel rod impalement injuries involving the spine: A case report and literature review. 38
31297784 2019
29
Transumbilical minilaparotomy in low-birthweight newborns for complicated conditions. 38
30145106 2019
30
Short- and Long-Term Outcomes of Extremely Preterm Infants in Japan According to Outborn/Inborn Birth Status. 38
31232855 2019
31
Anaplastic Large T-Cell Lymphoma in the Intestine of Dogs. 38
31170900 2019
32
Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial. 38
31003911 2019
33
A Catastrophic Case of Idiopathic Cholesterol Crystal Embolism with Multiple Lethal Complications: A Labyrinth Underneath the Diagnosis of Skin Ulcers in Chronic Kidney Disease Patients. 38
30713332 2019
34
Analysis of the use of upright abdominal radiography for evaluating intestinal perforations in handlebar traumas: Three case reports. 38
31169697 2019
35
Prolonged duration of early antibiotic therapy in extremely premature infants. 38
30737489 2019
36
Monomicrobial non-neutrocytic bacterascites caused by aeromonas hydrophila in a patient with liver cirrhosis. 38
31124459 2019
37
Early post-liver transplant surgical morbidity in HIV-infected recipients: risk factor for overall survival? A nationwide retrospective study. 38
31050044 2019
38
Staging of necrotising enterocolitis by Bell's criteria is supported by a statistical pattern analysis of clinical and radiological variables. 38
29926969 2019
39
The role of magnesium sulfate (MgSO4) in fetal neuroprotection. 38
31092073 2019
40
Spontaneous pneumothorax and hemothorax frequently precede the arterial and intestinal complications of vascular Ehlers-Danlos syndrome. 38
30793832 2019
41
[A case of multiple intestinal perforation secondary to paclitaxel and carboplatin combined chemotherapy for lung cancer]. 38
31137178 2019
42
Pneumoperitoneum after Endoscopic Duodenal Stent Insertion in a Patient with Percutaneous Transhepatic Biliary Drainage and Biliary Stent: A Case Report. 38
30153723 2019
43
Lymphangiomatosis of the ileum with perforation: A case report and review of the literature. 38
30992989 2019
44
Successful staged repair of pulmonary atresia, ventricular septal defect, and major aortopulmonary collateral arteries in an extremely low birth weight infant. 38
31147961 2019
45
Intestinal Perforation Secondary to Pits of Jujube Ingestion: A Single-Center Experience with 18 Cases. 38
30659341 2019
46
Ongoing Computed Tomography Appraisal of Intestinal Perforation Due to an Ingested Foreign Body. 38
31043580 2019
47
Impact of practice change on intestinal perforation risk for pediatric gastrojejunostomy tube placement. 38
30819544 2019
48
Rectovaginal fistula during treatment with axitinib in a patient with renal cell carcinoma: a case report and review of the literature. 38
30640790 2019
49
Prolonged early antenatal indomethacin exposure is safe for fetus and neonate. 38
30905227 2019
50
Outcomes of infants born at 23 and 24 weeks' gestation with gut perforation. 38
31072679 2019

Variations for Intestinal Perforation

Expression for Intestinal Perforation

Search GEO for disease gene expression data for Intestinal Perforation.

Pathways for Intestinal Perforation

Pathways related to Intestinal Perforation according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.01 PRODH NOS1
2
Show member pathways
10.76 NOS1 NFKB1
3 10.4 NOS1 NFKB1
4 9.98 NOD2 NFKB1

GO Terms for Intestinal Perforation

Cellular components related to Intestinal Perforation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrion GO:0005739 9.02 PTS PRODH NOS1 NOD2 NFKB1

Biological processes related to Intestinal Perforation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 interleukin-1-mediated signaling pathway GO:0070498 8.96 NOD2 NFKB1
2 cellular response to lipopolysaccharide GO:0071222 8.8 NOD2 NFKB1 DEFA4

Molecular functions related to Intestinal Perforation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977 8.8 PRDM6 NKX2-1 NFKB1

Sources for Intestinal Perforation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....