MCID: INT046
MIFTS: 37

Intestinal Tuberculosis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Intestinal Tuberculosis

MalaCards integrated aliases for Intestinal Tuberculosis:

Name: Intestinal Tuberculosis 12 15
Tuberculosis of Intestines 74
Tuberculosis of Intestine 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13282
ICD9CM 36 014.8

Summaries for Intestinal Tuberculosis

Disease Ontology : 12 A gastrointestinal tuberculosis that involves diffuse mucosal fold thickening, formation of ulcers and fistulae located in intestine. The infection has symptom abdominal pain, has symptom gastrointestinal bleeding, has symptom nausea and has symptom vomiting.

MalaCards based summary : Intestinal Tuberculosis, also known as tuberculosis of intestines, is related to gastrointestinal tuberculosis and abdominal tuberculosis, and has symptoms including vomiting, abdominal pain and nausea. An important gene associated with Intestinal Tuberculosis is NT5E (5'-Nucleotidase Ecto), and among its related pathways/superpathways is Development_Leptin signaling via JAK/STAT and MAPK cascades. The drugs Antitubercular Agents and Cola have been mentioned in the context of this disorder. Affiliated tissues include liver, colon and small intestine, and related phenotype is cardiovascular system.

Related Diseases for Intestinal Tuberculosis

Graphical network of the top 20 diseases related to Intestinal Tuberculosis:



Diseases related to Intestinal Tuberculosis

Symptoms & Phenotypes for Intestinal Tuberculosis

Symptoms:

12
  • vomiting
  • abdominal pain
  • nausea
  • gastrointestinal bleeding

MGI Mouse Phenotypes related to Intestinal Tuberculosis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.02 ABCA3 ABCB8 CRP NT5E PLA2G4A

Drugs & Therapeutics for Intestinal Tuberculosis

Drugs for Intestinal Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antitubercular Agents Phase 3
2 Cola
3 Liver Extracts

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Treatment Duration for Abdominal Tuberculosis Completed NCT01124929 Phase 3 RNTCP Category I treatment for 6 months;RNTCP Category I treatment for 9months
2 Intestinal Tuberculosis Diagnostics and the Differentiation From Crohn's Disease Unknown status NCT01503099
3 Development of a Prediction Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease Completed NCT01392365
4 MRI Differentiating Gut TB and Crohn's Completed NCT03096379
5 Prevalence of Colon Cancer in Pyogenic Liver Abscess Completed NCT02032914

Search NIH Clinical Center for Intestinal Tuberculosis

Genetic Tests for Intestinal Tuberculosis

Anatomical Context for Intestinal Tuberculosis

MalaCards organs/tissues related to Intestinal Tuberculosis:

42
Liver, Colon, Small Intestine, Testes, Kidney, Heart, Pancreas

The Foundational Model of Anatomy Ontology organs/tissues related to Intestinal Tuberculosis:

20
Intestine

Publications for Intestinal Tuberculosis

Articles related to Intestinal Tuberculosis:

(show top 50) (show all 335)
# Title Authors Year
1
Differentiating Crohn's disease from intestinal tuberculosis. ( 30700939 )
2019
2
Intestinal tuberculosis: clinico-pathological profile and the importance of a high degree of suspicion. ( 30338607 )
2019
3
Intestinal Tuberculosis: A Rare Case of Massive Gastrointestinal Bleed in a Post-Renal Transplant Recipient. ( 30983756 )
2019
4
Making a Positive Diagnosis of Intestinal Tuberculosis with the Aid of New Biologic and Histologic Features: How Far Have We Reached? ( 31111030 )
2019
5
Ten Cases of Intestinal Tuberculosis which Were Initially Misdiagnosed as Inflammatory Bowel Disease. ( 30918188 )
2019
6
Intestinal tuberculosis simulating Crohn's disease: Differential diagnosis. ( 29548741 )
2019
7
Development and Validation of a Novel Diagnostic Nomogram to Differentiate Between Intestinal Tuberculosis and Crohn's Disease: A 6-year Prospective Multicenter Study. ( 30741735 )
2019
8
Correction: Exploration of Serum Proteomic Profiling and Diagnostic Model That Differentiate Crohn's Disease and Intestinal Tuberculosis. ( 30730981 )
2019
9
Analysis of Phenotypic Variables and Differentiation Between Untypical Crohn's Disease and Untypical Intestinal Tuberculosis. ( 30725295 )
2019
10
All that fistulises is not Crohn's disease: Multiple entero-enteric fistulae in intestinal tuberculosis. ( 30919818 )
2019
11
The Polymorphism rs17525495 of LTA4H Is Associated with Susceptibility of Crohn's Disease instead of Intestinal Tuberculosis in a Chinese Han Population. ( 31093505 )
2019
12
CD73 expression in tissue granulomas in distinguishing intestinal tuberculosis from Crohn's disease in a South African cohort. ( 30295112 )
2018
13
Antibodies against glycoprotein 2 display diagnostic advantages over ASCA in distinguishing CD from intestinal tuberculosis and intestinal Behçet's disease. ( 29446764 )
2018
14
Clinical and laboratory features of intestinal tuberculosis. ( 29559804 )
2018
15
Intestinal tuberculosis in a 55-year-old woman with a 30-year history of rheumatoid arthritis. ( 30022862 )
2018
16
Chicken intestine: Intestinal tuberculosis. ( 30309155 )
2018
17
Goose neck: Intestinal tuberculosis. ( 30309187 )
2018
18
Diagnostic Accuracy of Peritoneal Fluid GeneXpert in the Diagnosis of Intestinal Tuberculosis, Keeping Histopathology as the Gold Standard. ( 30564530 )
2018
19
Primary enterolithiasis with intestinal tuberculosis: rare presentation of a common disease. ( 30580291 )
2018
20
Combination of increased visceral fat and long segment involvement: Development and validation of an updated imaging marker for differentiating Crohn's disease from intestinal tuberculosis. ( 29205485 )
2018
21
CD4+ CD25+ FOXP3+ T cell frequency in the peripheral blood is a biomarker that distinguishes intestinal tuberculosis from Crohn's disease. ( 29489879 )
2018
22
Letter: mucosal response in discriminating intestinal tuberculosis from Crohn's disease-when to look for it? Authors' reply. ( 29446137 )
2018
23
Letter: mucosal response in discriminating intestinal tuberculosis from Crohn's disease-when to look for it? ( 29446132 )
2018
24
Ileum Histoplasmosis Mimicking Intestinal Tuberculosis and Crohn's Disease. ( 29515346 )
2018
25
Diagnostic Performance of a 5-Marker Predictive Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease. ( 29860270 )
2018
26
Differentiating Crohn's disease from intestinal tuberculosis at presentation in patients with tissue granulomas. ( 29843853 )
2018
27
Intestinal tuberculosis and Crohn's disease: the importance and difficulty of a differential diagnosis. ( 30168341 )
2018
28
Selective M1 macrophage polarization in granuloma-positive and granuloma-negative Crohn's disease, in comparison to intestinal tuberculosis. ( 30090042 )
2018
29
Differentiation Between Crohn Disease and Intestinal Tuberculosis in Children. ( 28489674 )
2018
30
Pulmonary actinomycosis coexisting with intestinal tuberculosis as a complication of adalimumab treatment for Crohn's disease. ( 29560655 )
2017
31
Development and Validation of a Novel Prediction Model for Differential Diagnosis Between Crohn's Disease and Intestinal Tuberculosis. ( 28682807 )
2017
32
Accuracy of computed tomographic features in differentiating intestinal tuberculosis from Crohn's disease: a systematic review with meta-analysis. ( 28522943 )
2017
33
Multiple jejunal perforation secondary to intestinal tuberculosis infection: a case report. ( 28819499 )
2017
34
Caecal Perforation from Primary Intestinal Tuberculosis in Pregnancy. ( 28912984 )
2017
35
Drug resistance in intestinal tuberculosis: A reason to worry? ( 30483528 )
2017
36
Development and validation of visceral fat quantification as a surrogate marker for differentiation of Crohn's disease and intestinal tuberculosis. ( 27532624 )
2017
37
Endoscopic and clinical responses to anti-tubercular therapy can differentiate intestinal tuberculosis from Crohn's disease. ( 27813111 )
2017
38
The diagnostic value of polymerase chain reaction for Mycobacterium tuberculosis to distinguish intestinal tuberculosis from crohn's disease: A meta-analysis. ( 28139494 )
2017
39
Predictive Model for Differentiating Crohn's Disease and Intestinal Tuberculosis: The Story Is Incomplete Without Imaging. ( 28050042 )
2017
40
Meta-Analytic Bayesian Model For Differentiating Intestinal Tuberculosis from Crohn's Disease. ( 28045023 )
2017
41
Temporal trends in the misdiagnosis rates between Crohn's disease and intestinal tuberculosis. ( 28974897 )
2017
42
Endoscopic Treatment of Intussusception due to Intestinal Tuberculosis. ( 28030916 )
2017
43
Intestinal Tuberculosis Presenting as an Apple-Core Sign. ( 28270663 )
2017
44
Intestinal tuberculosis: a diagnostic challenge. ( 28609809 )
2017
45
Is it intestinal tuberculosis again? Case report. ( 28726436 )
2017
46
Intestinal tuberculosis versus crohn's disease: Clinical and radiological recommendations. ( 27413261 )
2016
47
The use of Masson's trichrome staining, second harmonic imaging and two-photon excited fluorescence of collagen in distinguishing intestinal tuberculosis from Crohn's disease. ( 27232282 )
2016
48
Misdiagnosis and Mistherapy of Crohn's Disease as Intestinal Tuberculosis: Case Report and Literature Review. ( 26735549 )
2016
49
Intestinal tuberculosis and Crohn's disease: challenging differential diagnosis. ( 26854750 )
2016
50
Proteome analysis of the macroscopically affected colonic mucosa of Crohn's disease and intestinal tuberculosis. ( 26988818 )
2016

Variations for Intestinal Tuberculosis

Expression for Intestinal Tuberculosis

Search GEO for disease gene expression data for Intestinal Tuberculosis.

Pathways for Intestinal Tuberculosis

Pathways related to Intestinal Tuberculosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.1 CRP PLA2G4A

GO Terms for Intestinal Tuberculosis

Cellular components related to Intestinal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 anchored component of membrane GO:0031225 8.62 GP2 NT5E

Molecular functions related to Intestinal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transporter activity GO:0005215 8.96 ABCA3 ABCB8
2 ATPase activity, coupled to transmembrane movement of substances GO:0042626 8.62 ABCA3 ABCB8

Sources for Intestinal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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