MCID: INT046
MIFTS: 35

Intestinal Tuberculosis

Categories: Infectious diseases, Gastrointestinal diseases

Aliases & Classifications for Intestinal Tuberculosis

MalaCards integrated aliases for Intestinal Tuberculosis:

Name: Intestinal Tuberculosis 12 15
Tuberculosis of Intestines 73
Tuberculosis of Intestine 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13282
ICD9CM 35 014.8

Summaries for Intestinal Tuberculosis

Disease Ontology : 12 A gastrointestinal tuberculosis that involves diffuse mucosal fold thickening, formation of ulcers and fistulae located in intestine. The infection has symptom abdominal pain, has symptom gastrointestinal bleeding, has symptom nausea and has symptom vomiting.

MalaCards based summary : Intestinal Tuberculosis, also known as tuberculosis of intestines, is related to gastrointestinal tuberculosis and intussusception, and has symptoms including abdominal pain, gastrointestinal bleeding and nausea. An important gene associated with Intestinal Tuberculosis is NT5E (5'-Nucleotidase Ecto). The drugs Antitubercular Agents and Liver Extracts have been mentioned in the context of this disorder. Affiliated tissues include intestine, liver and colon.

Related Diseases for Intestinal Tuberculosis

Diseases related to Intestinal Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
# Related Disease Score Top Affiliating Genes
1 gastrointestinal tuberculosis 32.7 ABCB8 CD53
2 intussusception 29.3 CD79A CRP
3 abdominal tuberculosis 29.2 ABCB8 CRP
4 purpura 28.6 CD79A CRP
5 crohn's disease 10.5
6 pulmonary tuberculosis 10.0
7 peritonitis 9.9
8 lymphoma 9.9
9 colitis 9.8
10 mucositis 9.8
11 tuberculous peritonitis 9.8
12 ulcerative colitis 9.7
13 inflammatory bowel disease 9.7
14 acute maxillary sinusitis 9.7 CD79A CRP
15 rapidly progressive glomerulonephritis 9.7 CD79A CRP
16 hypersensitivity vasculitis 9.7 CD79A CRP
17 hypersensitivity reaction type iii disease 9.7 CD79A CRP
18 pyelitis 9.7 CD79A CRP
19 endocardium disease 9.6 CD79A CRP
20 dysentery 9.6 CD79A CRP
21 granulomatous hepatitis 9.6 CD79A CRP
22 lymph node disease 9.6 CD79A CRP
23 exanthem 9.6 CD79A CRP
24 reactive arthritis 9.6 CD79A CRP
25 spondyloarthropathy 1 9.6 CD79A CRP
26 primary bacterial infectious disease 9.6 CD79A CRP
27 chlamydia 9.6 CD79A CRP
28 bone inflammation disease 9.6 CD79A CRP
29 colorectal cancer 9.6
30 rheumatoid arthritis 9.6
31 anemia, autoimmune hemolytic 9.6
32 celiac disease 1 9.6
33 hypoascorbemia 9.6
34 helicobacter pylori infection 9.6
35 arthritis 9.6
36 chronic inflammatory demyelinating polyneuropathy 9.6
37 hemolytic anemia 9.6
38 small intestine lymphoma 9.6
39 secretory diarrhea 9.6
40 inguinal hernia 9.6
41 esophagitis 9.6
42 dementia 9.6
43 esophageal candidiasis 9.6
44 diarrhea 9.6
45 polyneuropathy 9.6
46 schistosomiasis 9.6
47 candidiasis 9.6
48 lymphadenitis 9.6
49 histoplasmosis 9.6
50 demyelinating polyneuropathy 9.6

Graphical network of the top 20 diseases related to Intestinal Tuberculosis:



Diseases related to Intestinal Tuberculosis

Symptoms & Phenotypes for Intestinal Tuberculosis

Symptoms:

12
  • abdominal pain
  • gastrointestinal bleeding
  • nausea
  • vomiting

Drugs & Therapeutics for Intestinal Tuberculosis

Drugs for Intestinal Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antitubercular Agents Phase 3
2 Liver Extracts
3 Cola Nutraceutical

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Treatment Duration for Abdominal Tuberculosis Completed NCT01124929 Phase 3 RNTCP Category I treatment for 6 months;RNTCP Category I treatment for 9months
2 Intestinal Tuberculosis Diagnostics and the Differentiation From Crohn's Disease Unknown status NCT01503099
3 Development of a Prediction Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease Completed NCT01392365
4 Prevalence of Colon Cancer in Pyogenic Liver Abscess Completed NCT02032914
5 MRI Differentiating Gut TB and Crohn's Recruiting NCT03096379

Search NIH Clinical Center for Intestinal Tuberculosis

Genetic Tests for Intestinal Tuberculosis

Anatomical Context for Intestinal Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Intestinal Tuberculosis:

19
Intestine

MalaCards organs/tissues related to Intestinal Tuberculosis:

41
Liver, Colon, Testes, Small Intestine, T Cells, Appendix, Heart

Publications for Intestinal Tuberculosis

Articles related to Intestinal Tuberculosis:

(show top 50) (show all 300)
# Title Authors Year
1
Letter: mucosal response in discriminating intestinal tuberculosis from Crohn's disease-when to look for it? ( 29446132 )
2018
2
Antibodies against glycoprotein 2 display diagnostic advantages over ASCA in distinguishing CD from intestinal tuberculosis and intestinal BehAset's disease. ( 29446764 )
2018
3
Ileum Histoplasmosis Mimicking Intestinal Tuberculosis and Crohn's Disease. ( 29515346 )
2018
4
Diagnostic Performance of a 5-Marker Predictive Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease. ( 29860270 )
2018
5
Letter: mucosal response in discriminating intestinal tuberculosis from Crohn's disease-when to look for it? Authors' reply. ( 29446137 )
2018
6
Intestinal tuberculosis simulating Crohn's disease: Differential diagnosis. ( 29548741 )
2018
7
Clinical and laboratory features of intestinal tuberculosis. ( 29559804 )
2018
8
Differentiating Crohn's disease from intestinal tuberculosis at presentation in patients with tissue granulomas. ( 29843853 )
2018
9
CD4+ CD25+ FOXP3+ T cell frequency in the peripheral blood is a biomarker that distinguishes intestinal tuberculosis from Crohn's disease. ( 29489879 )
2018
10
Intestinal tuberculosis: a diagnostic challenge. ( 28609809 )
2017
11
Development and Validation of a Novel Prediction Model for Differential Diagnosis Between Crohn's Disease and Intestinal Tuberculosis. ( 28682807 )
2017
12
Endoscopic and clinical responses to anti-tubercular therapy can differentiate intestinal tuberculosis from Crohn's disease. ( 27813111 )
2017
13
Pulmonary actinomycosis coexisting with intestinal tuberculosis as a complication of adalimumab treatment for Crohn's disease. ( 29560655 )
2017
14
Combination of Increased Visceral Fat and Long Segment Involvement: Development and Validation of an updated imaging marker for differentiating Crohn's Disease from Intestinal Tuberculosis. ( 29205485 )
2017
15
Accuracy of computed tomographic features in differentiating intestinal tuberculosis from Crohn's disease: a systematic review with meta-analysis. ( 28522943 )
2017
16
Temporal trends in the misdiagnosis rates between Crohn's disease and intestinal tuberculosis. ( 28974897 )
2017
17
Is it intestinal tuberculosis again? Case report. ( 28726436 )
2017
18
Caecal Perforation from Primary Intestinal Tuberculosis in Pregnancy. ( 28912984 )
2017
19
Multiple jejunal perforation secondary to intestinal tuberculosis infection: a case report. ( 28819499 )
2017
20
Predictive Model for Differentiating Crohn's Disease and Intestinal Tuberculosis: The Story Is Incomplete Without Imaging. ( 28050042 )
2017
21
The diagnostic value of polymerase chain reaction for Mycobacterium tuberculosis to distinguish intestinal tuberculosis from crohn's disease: A meta-analysis. ( 28139494 )
2017
22
Intestinal Tuberculosis Presenting as an Apple-Core Sign. ( 28270663 )
2017
23
Differentiation between Crohn's Disease and Intestinal Tuberculosis in Children. ( 28489674 )
2017
24
Meta-Analytic Bayesian Model For Differentiating Intestinal Tuberculosis from Crohn's Disease. ( 28045023 )
2017
25
Proteome analysis of the macroscopically affected colonic mucosa of Crohn's disease and intestinal tuberculosis. ( 26988818 )
2016
26
Intestinal tuberculosis and Crohn's disease: challenging differential diagnosis. ( 26854750 )
2016
27
Endoscopic Treatment of Intussusception due to Intestinal Tuberculosis. ( 28030916 )
2016
28
Clinical and Laboratory Diagnosis of Intestinal Tuberculosis. ( 27231171 )
2016
29
The use of Masson's trichrome staining, second harmonic imaging and two-photon excited fluorescence of collagen in distinguishing intestinal tuberculosis from Crohn's disease. ( 27232282 )
2016
30
Intestinal tuberculosis versus crohn's disease: Clinical and radiological recommendations. ( 27413261 )
2016
31
Primary Enterolith in a Patient with Intestinal Tuberculosis: A Case Report. ( 27853338 )
2016
32
Predictive Factors for Differentiating Between Crohn's Disease and Intestinal Tuberculosis in Koreans. ( 27296940 )
2016
33
An Analysis of the Clinical, Endoscopic, and Pathologic Features of Intestinal Tuberculosis. ( 26974755 )
2016
34
Intestinal tuberculosis masquerading as difficult to treat Crohn disease: a case report. ( 27557645 )
2016
35
Exploration of Serum Proteomic Profiling and Diagnostic Model That Differentiate Crohn's Disease and Intestinal Tuberculosis. ( 27997555 )
2016
36
Misdiagnosis and Mistherapy of Crohn's Disease as Intestinal Tuberculosis: Case Report and Literature Review. ( 26735549 )
2016
37
Development and validation of visceral fat quantification as a surrogate marker for differentiation of Crohn's disease and Intestinal tuberculosis. ( 27532624 )
2016
38
Differences in Clinical Manifestations according to the Positivity of Interferon-I^ Assay in Patients with Intestinal Tuberculosis. ( 27282272 )
2016
39
Perforated Intestinal Tuberculosis in a Non-AIDS Immunocompromised Patient. ( 26451879 )
2015
40
Evaluation of intestinal tuberculosis by multi-slice computed tomography enterography. ( 26695641 )
2015
41
Subcutaneous abscess at epidural catheter insertion site in a patient with intestinal tuberculosis. ( 26111664 )
2015
42
Differences in clinical features of Crohn's disease and intestinal tuberculosis. ( 25834333 )
2015
43
Combined identifying granuloma and biopsy culture is useful for diagnosing intestinal tuberculosis. ( 25868516 )
2015
44
High faecal calprotectin levels in intestinal tuberculosis are associated with granulomas in intestinal biopsies. ( 25522183 )
2015
45
Intestinal tuberculosis previously mistreated as Crohn's disease and complicated with perforation: a case report and literature review. ( 26180746 )
2015
46
P139. Predictive Factors for Differentiating between Crohn's disease and Intestinal tuberculosis in Korea. ( 25717600 )
2015
47
Seminar Report From the 2014 Taiwan Society of Inflammatory Bowel Disease (TSIBD) Spring Forum (May 24th, 2014): Crohn's Disease Versus Intestinal Tuberculosis Infection. ( 25691838 )
2015
48
Extraintestinal manifestations of inflammatory bowel disease and intestinal tuberculosis: Frequency and relation with disease phenotype. ( 25663290 )
2015
49
Critical complications of intestinal tuberculosis--a case report. ( 26305349 )
2015
50
Granulomas as the Most Useful Histopathological Feature in Distinguishing between Crohn's Disease and Intestinal Tuberculosis in Endoscopic Biopsy Specimens. ( 26656343 )
2015

Variations for Intestinal Tuberculosis

Expression for Intestinal Tuberculosis

Search GEO for disease gene expression data for Intestinal Tuberculosis.

Pathways for Intestinal Tuberculosis

GO Terms for Intestinal Tuberculosis

Cellular components related to Intestinal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 anchored component of membrane GO:0031225 8.62 GP2 NT5E

Sources for Intestinal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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