MCID: INT046
MIFTS: 37

Intestinal Tuberculosis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Intestinal Tuberculosis

MalaCards integrated aliases for Intestinal Tuberculosis:

Name: Intestinal Tuberculosis 12 15
Tuberculosis of Intestines 73
Tuberculosis of Intestine 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13282
ICD9CM 35 014.8

Summaries for Intestinal Tuberculosis

Disease Ontology : 12 A gastrointestinal tuberculosis that involves diffuse mucosal fold thickening, formation of ulcers and fistulae located in intestine. The infection has symptom abdominal pain, has symptom gastrointestinal bleeding, has symptom nausea and has symptom vomiting.

MalaCards based summary : Intestinal Tuberculosis, also known as tuberculosis of intestines, is related to gastrointestinal tuberculosis and abdominal tuberculosis, and has symptoms including vomiting, abdominal pain and nausea. An important gene associated with Intestinal Tuberculosis is NT5E (5'-Nucleotidase Ecto). The drugs Antitubercular Agents and Cola have been mentioned in the context of this disorder. Affiliated tissues include liver, colon and testes, and related phenotype is cardiovascular system.

Related Diseases for Intestinal Tuberculosis

Graphical network of the top 20 diseases related to Intestinal Tuberculosis:



Diseases related to Intestinal Tuberculosis

Symptoms & Phenotypes for Intestinal Tuberculosis

Symptoms:

12
  • vomiting
  • abdominal pain
  • nausea
  • gastrointestinal bleeding

MGI Mouse Phenotypes related to Intestinal Tuberculosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.02 ABCA3 ABCB8 CRP LOXL2 NT5E

Drugs & Therapeutics for Intestinal Tuberculosis

Drugs for Intestinal Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antitubercular Agents Phase 3
2 Cola
3 Liver Extracts

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Treatment Duration for Abdominal Tuberculosis Completed NCT01124929 Phase 3 RNTCP Category I treatment for 6 months;RNTCP Category I treatment for 9months
2 Intestinal Tuberculosis Diagnostics and the Differentiation From Crohn's Disease Unknown status NCT01503099
3 Development of a Prediction Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease Completed NCT01392365
4 Prevalence of Colon Cancer in Pyogenic Liver Abscess Completed NCT02032914
5 MRI Differentiating Gut TB and Crohn's Recruiting NCT03096379

Search NIH Clinical Center for Intestinal Tuberculosis

Genetic Tests for Intestinal Tuberculosis

Anatomical Context for Intestinal Tuberculosis

MalaCards organs/tissues related to Intestinal Tuberculosis:

41
Liver, Colon, Testes, Small Intestine, Kidney, Heart, Lung

The Foundational Model of Anatomy Ontology organs/tissues related to Intestinal Tuberculosis:

19
Intestine

Publications for Intestinal Tuberculosis

Articles related to Intestinal Tuberculosis:

(show top 50) (show all 325)
# Title Authors Year
1
Letter: mucosal response in discriminating intestinal tuberculosis from Crohn's disease-when to look for it? ( 29446132 )
2018
2
Antibodies against glycoprotein 2 display diagnostic advantages over ASCA in distinguishing CD from intestinal tuberculosis and intestinal BehAset's disease. ( 29446764 )
2018
3
Ileum Histoplasmosis Mimicking Intestinal Tuberculosis and Crohn's Disease. ( 29515346 )
2018
4
Diagnostic Performance of a 5-Marker Predictive Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease. ( 29860270 )
2018
5
Letter: mucosal response in discriminating intestinal tuberculosis from Crohn's disease-when to look for it? Authors' reply. ( 29446137 )
2018
6
Intestinal tuberculosis simulating Crohn's disease: Differential diagnosis. ( 29548741 )
2018
7
Clinical and laboratory features of intestinal tuberculosis. ( 29559804 )
2018
8
Differentiating Crohn's disease from intestinal tuberculosis at presentation in patients with tissue granulomas. ( 29843853 )
2018
9
CD4+ CD25+ FOXP3+ T cell frequency in the peripheral blood is a biomarker that distinguishes intestinal tuberculosis from Crohn's disease. ( 29489879 )
2018
10
CD73 expression in tissue granulomas in distinguishing intestinal tuberculosis from Crohn's disease in a South African cohort. ( 30295112 )
2018
11
Selective M1 macrophage polarization in granuloma-positive and granuloma-negative Crohn's disease, in comparison to intestinal tuberculosis. ( 30090042 )
2018
12
Intestinal tuberculosis and Crohn's disease: the importance and difficulty of a differential diagnosis. ( 30168341 )
2018
13
Differentiation Between Crohn Disease and Intestinal Tuberculosis in Children. ( 28489674 )
2018
14
Intestinal tuberculosis in a 55-year-old woman with a 30-year history of rheumatoid arthritis. ( 30022862 )
2018
15
Chicken intestine: Intestinal tuberculosis. ( 30309155 )
2018
16
Goose neck: Intestinal tuberculosis. ( 30309187 )
2018
17
Intestinal tuberculosis: clinico-pathological profile and the importance of a high degree of suspicion. ( 30338607 )
2018
18
Intestinal tuberculosis: a diagnostic challenge. ( 28609809 )
2017
19
Development and Validation of a Novel Prediction Model for Differential Diagnosis Between Crohn's Disease and Intestinal Tuberculosis. ( 28682807 )
2017
20
Endoscopic and clinical responses to anti-tubercular therapy can differentiate intestinal tuberculosis from Crohn's disease. ( 27813111 )
2017
21
Pulmonary actinomycosis coexisting with intestinal tuberculosis as a complication of adalimumab treatment for Crohn's disease. ( 29560655 )
2017
22
Combination of Increased Visceral Fat and Long Segment Involvement: Development and Validation of an updated imaging marker for differentiating Crohn's Disease from Intestinal Tuberculosis. ( 29205485 )
2017
23
Accuracy of computed tomographic features in differentiating intestinal tuberculosis from Crohn's disease: a systematic review with meta-analysis. ( 28522943 )
2017
24
Temporal trends in the misdiagnosis rates between Crohn's disease and intestinal tuberculosis. ( 28974897 )
2017
25
Is it intestinal tuberculosis again? Case report. ( 28726436 )
2017
26
Caecal Perforation from Primary Intestinal Tuberculosis in Pregnancy. ( 28912984 )
2017
27
Multiple jejunal perforation secondary to intestinal tuberculosis infection: a case report. ( 28819499 )
2017
28
Predictive Model for Differentiating Crohn's Disease and Intestinal Tuberculosis: The Story Is Incomplete Without Imaging. ( 28050042 )
2017
29
The diagnostic value of polymerase chain reaction for Mycobacterium tuberculosis to distinguish intestinal tuberculosis from crohn's disease: A meta-analysis. ( 28139494 )
2017
30
Intestinal Tuberculosis Presenting as an Apple-Core Sign. ( 28270663 )
2017
31
Meta-Analytic Bayesian Model For Differentiating Intestinal Tuberculosis from Crohn's Disease. ( 28045023 )
2017
32
Drug resistance in intestinal tuberculosis: A reason to worry? ( 30483528 )
2017
33
Proteome analysis of the macroscopically affected colonic mucosa of Crohn's disease and intestinal tuberculosis. ( 26988818 )
2016
34
Intestinal tuberculosis and Crohn's disease: challenging differential diagnosis. ( 26854750 )
2016
35
Endoscopic Treatment of Intussusception due to Intestinal Tuberculosis. ( 28030916 )
2016
36
Clinical and Laboratory Diagnosis of Intestinal Tuberculosis. ( 27231171 )
2016
37
The use of Masson's trichrome staining, second harmonic imaging and two-photon excited fluorescence of collagen in distinguishing intestinal tuberculosis from Crohn's disease. ( 27232282 )
2016
38
Intestinal tuberculosis versus crohn's disease: Clinical and radiological recommendations. ( 27413261 )
2016
39
Primary Enterolith in a Patient with Intestinal Tuberculosis: A Case Report. ( 27853338 )
2016
40
Predictive Factors for Differentiating Between Crohn's Disease and Intestinal Tuberculosis in Koreans. ( 27296940 )
2016
41
An Analysis of the Clinical, Endoscopic, and Pathologic Features of Intestinal Tuberculosis. ( 26974755 )
2016
42
Intestinal tuberculosis masquerading as difficult to treat Crohn disease: a case report. ( 27557645 )
2016
43
Exploration of Serum Proteomic Profiling and Diagnostic Model That Differentiate Crohn's Disease and Intestinal Tuberculosis. ( 27997555 )
2016
44
Misdiagnosis and Mistherapy of Crohn's Disease as Intestinal Tuberculosis: Case Report and Literature Review. ( 26735549 )
2016
45
Development and validation of visceral fat quantification as a surrogate marker for differentiation of Crohn's disease and Intestinal tuberculosis. ( 27532624 )
2016
46
Genome-wide gene expression analysis for target genes to differentiate patients with intestinal tuberculosis and Crohn's disease and discriminative value of FOXP3 mRNA expression. ( 25969456 )
2016
47
Differences in Clinical Manifestations according to the Positivity of Interferon-γ Assay in Patients with Intestinal Tuberculosis. ( 27282272 )
2016
48
Perforated Intestinal Tuberculosis in a Non-AIDS Immunocompromised Patient. ( 26451879 )
2015
49
Evaluation of intestinal tuberculosis by multi-slice computed tomography enterography. ( 26695641 )
2015
50
Subcutaneous abscess at epidural catheter insertion site in a patient with intestinal tuberculosis. ( 26111664 )
2015

Variations for Intestinal Tuberculosis

Expression for Intestinal Tuberculosis

Search GEO for disease gene expression data for Intestinal Tuberculosis.

Pathways for Intestinal Tuberculosis

GO Terms for Intestinal Tuberculosis

Cellular components related to Intestinal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 anchored component of membrane GO:0031225 8.62 GP2 NT5E

Molecular functions related to Intestinal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transporter activity GO:0005215 8.96 ABCA3 ABCB8
2 ATPase activity, coupled to transmembrane movement of substances GO:0042626 8.62 ABCA3 ABCB8

Sources for Intestinal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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