MCID: INT046
MIFTS: 37

Intestinal Tuberculosis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Intestinal Tuberculosis

MalaCards integrated aliases for Intestinal Tuberculosis:

Name: Intestinal Tuberculosis 12 15
Tuberculosis of Intestines 74
Tuberculosis of Intestine 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13282
ICD9CM 36 014.8

Summaries for Intestinal Tuberculosis

Disease Ontology : 12 A gastrointestinal tuberculosis that involves diffuse mucosal fold thickening, formation of ulcers and fistulae located in intestine. The infection has symptom abdominal pain, has symptom gastrointestinal bleeding, has symptom nausea and has symptom vomiting.

MalaCards based summary : Intestinal Tuberculosis, also known as tuberculosis of intestines, is related to gastrointestinal tuberculosis and abdominal tuberculosis, and has symptoms including vomiting, abdominal pain and nausea. An important gene associated with Intestinal Tuberculosis is NT5E (5'-Nucleotidase Ecto). The drugs Antitubercular Agents and Liver Extracts have been mentioned in the context of this disorder. Affiliated tissues include liver, colon and testes, and related phenotype is cardiovascular system.

Related Diseases for Intestinal Tuberculosis

Diseases related to Intestinal Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
# Related Disease Score Top Affiliating Genes
1 gastrointestinal tuberculosis 31.9 ABCB8 CD53 CRP
2 abdominal tuberculosis 29.1 ABCB8 CRP
3 crohn's disease 10.7
4 mycobacterium tuberculosis 1 10.2
5 pulmonary tuberculosis 10.2
6 peritonitis 10.0
7 intussusception 10.0
8 lymphoma 10.0
9 colitis 9.9
10 tuberculous peritonitis 9.9
11 rheumatoid arthritis 9.8
12 arthritis 9.8
13 ulcerative colitis 9.8
14 inflammatory bowel disease 9.8
15 colorectal cancer 9.7
16 anemia, autoimmune hemolytic 9.7
17 celiac disease 1 9.7
18 hypoascorbemia 9.7
19 helicobacter pylori infection 9.7
20 chronic inflammatory demyelinating polyneuropathy 9.7
21 hemolytic anemia 9.7
22 secretory diarrhea 9.7
23 inguinal hernia 9.7
24 dementia 9.7
25 esophageal candidiasis 9.7
26 diarrhea 9.7
27 polyneuropathy 9.7
28 schistosomiasis 9.7
29 candidiasis 9.7
30 lymphadenitis 9.7
31 histoplasmosis 9.7
32 purpura 9.7
33 demyelinating polyneuropathy 9.7
34 actinomycosis 9.7
35 miliary tuberculosis 9.7

Graphical network of the top 20 diseases related to Intestinal Tuberculosis:



Diseases related to Intestinal Tuberculosis

Symptoms & Phenotypes for Intestinal Tuberculosis

Symptoms:

12
  • vomiting
  • abdominal pain
  • nausea
  • gastrointestinal bleeding

MGI Mouse Phenotypes related to Intestinal Tuberculosis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.02 ABCA3 ABCB8 CRP LOXL2 NT5E

Drugs & Therapeutics for Intestinal Tuberculosis

Drugs for Intestinal Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antitubercular Agents Phase 3
2 Liver Extracts
3 Cola

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Treatment Duration for Abdominal Tuberculosis Completed NCT01124929 Phase 3 RNTCP Category I treatment for 6 months;RNTCP Category I treatment for 9months
2 Intestinal Tuberculosis Diagnostics and the Differentiation From Crohn's Disease Unknown status NCT01503099
3 Development of a Prediction Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease Completed NCT01392365
4 Prevalence of Colon Cancer in Pyogenic Liver Abscess Completed NCT02032914
5 MRI Differentiating Gut TB and Crohn's Recruiting NCT03096379

Search NIH Clinical Center for Intestinal Tuberculosis

Genetic Tests for Intestinal Tuberculosis

Anatomical Context for Intestinal Tuberculosis

MalaCards organs/tissues related to Intestinal Tuberculosis:

42
Liver, Colon, Testes, Small Intestine, Kidney, Heart, Pancreas

The Foundational Model of Anatomy Ontology organs/tissues related to Intestinal Tuberculosis:

20
Intestine

Publications for Intestinal Tuberculosis

Articles related to Intestinal Tuberculosis:

(show top 50) (show all 332)
# Title Authors Year
1
Differentiating Crohn's disease from intestinal tuberculosis. ( 30700939 )
2019
2
Analysis of Phenotypic Variables and Differentiation Between Untypical Crohn's Disease and Untypical Intestinal Tuberculosis. ( 30725295 )
2019
3
Correction: Exploration of Serum Proteomic Profiling and Diagnostic Model That Differentiate Crohn's Disease and Intestinal Tuberculosis. ( 30730981 )
2019
4
Development and Validation of a Novel Diagnostic Nomogram to Differentiate Between Intestinal Tuberculosis and Crohn's Disease: A 6-year Prospective Multicenter Study. ( 30741735 )
2019
5
Letter: mucosal response in discriminating intestinal tuberculosis from Crohn's disease-when to look for it? ( 29446132 )
2018
6
Antibodies against glycoprotein 2 display diagnostic advantages over ASCA in distinguishing CD from intestinal tuberculosis and intestinal BehAset's disease. ( 29446764 )
2018
7
Ileum Histoplasmosis Mimicking Intestinal Tuberculosis and Crohn's Disease. ( 29515346 )
2018
8
Diagnostic Performance of a 5-Marker Predictive Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease. ( 29860270 )
2018
9
Letter: mucosal response in discriminating intestinal tuberculosis from Crohn's disease-when to look for it? Authors' reply. ( 29446137 )
2018
10
Intestinal tuberculosis simulating Crohn's disease: Differential diagnosis. ( 29548741 )
2018
11
Clinical and laboratory features of intestinal tuberculosis. ( 29559804 )
2018
12
Differentiating Crohn's disease from intestinal tuberculosis at presentation in patients with tissue granulomas. ( 29843853 )
2018
13
CD4+ CD25+ FOXP3+ T cell frequency in the peripheral blood is a biomarker that distinguishes intestinal tuberculosis from Crohn's disease. ( 29489879 )
2018
14
Intestinal tuberculosis in a 55-year-old woman with a 30-year history of rheumatoid arthritis. ( 30022862 )
2018
15
Intestinal tuberculosis and Crohn's disease: the importance and difficulty of a differential diagnosis. ( 30168341 )
2018
16
CD73 expression in tissue granulomas in distinguishing intestinal tuberculosis from Crohn's disease in a South African cohort. ( 30295112 )
2018
17
Selective M1 macrophage polarization in granuloma-positive and granuloma-negative Crohn's disease, in comparison to intestinal tuberculosis. ( 30090042 )
2018
18
Chicken intestine: Intestinal tuberculosis. ( 30309155 )
2018
19
Goose neck: Intestinal tuberculosis. ( 30309187 )
2018
20
Intestinal tuberculosis: clinico-pathological profile and the importance of a high degree of suspicion. ( 30338607 )
2018
21
Diagnostic Accuracy of Peritoneal Fluid GeneXpert in the Diagnosis of Intestinal Tuberculosis, Keeping Histopathology as the Gold Standard. ( 30564530 )
2018
22
Primary enterolithiasis with intestinal tuberculosis: rare presentation of a common disease. ( 30580291 )
2018
23
Intestinal tuberculosis: a diagnostic challenge. ( 28609809 )
2017
24
Development and Validation of a Novel Prediction Model for Differential Diagnosis Between Crohn's Disease and Intestinal Tuberculosis. ( 28682807 )
2017
25
Endoscopic and clinical responses to anti-tubercular therapy can differentiate intestinal tuberculosis from Crohn's disease. ( 27813111 )
2017
26
Pulmonary actinomycosis coexisting with intestinal tuberculosis as a complication of adalimumab treatment for Crohn's disease. ( 29560655 )
2017
27
Combination of Increased Visceral Fat and Long Segment Involvement: Development and Validation of an updated imaging marker for differentiating Crohn's Disease from Intestinal Tuberculosis. ( 29205485 )
2017
28
Accuracy of computed tomographic features in differentiating intestinal tuberculosis from Crohn's disease: a systematic review with meta-analysis. ( 28522943 )
2017
29
Temporal trends in the misdiagnosis rates between Crohn's disease and intestinal tuberculosis. ( 28974897 )
2017
30
Is it intestinal tuberculosis again? Case report. ( 28726436 )
2017
31
Caecal Perforation from Primary Intestinal Tuberculosis in Pregnancy. ( 28912984 )
2017
32
Multiple jejunal perforation secondary to intestinal tuberculosis infection: a case report. ( 28819499 )
2017
33
Predictive Model for Differentiating Crohn's Disease and Intestinal Tuberculosis: The Story Is Incomplete Without Imaging. ( 28050042 )
2017
34
The diagnostic value of polymerase chain reaction for Mycobacterium tuberculosis to distinguish intestinal tuberculosis from crohn's disease: A meta-analysis. ( 28139494 )
2017
35
Intestinal Tuberculosis Presenting as an Apple-Core Sign. ( 28270663 )
2017
36
Differentiation between Crohn's Disease and Intestinal Tuberculosis in Children. ( 28489674 )
2017
37
Meta-Analytic Bayesian Model For Differentiating Intestinal Tuberculosis from Crohn's Disease. ( 28045023 )
2017
38
Drug resistance in intestinal tuberculosis: A reason to worry? ( 30483528 )
2017
39
Proteome analysis of the macroscopically affected colonic mucosa of Crohn's disease and intestinal tuberculosis. ( 26988818 )
2016
40
Intestinal tuberculosis and Crohn's disease: challenging differential diagnosis. ( 26854750 )
2016
41
Endoscopic Treatment of Intussusception due to Intestinal Tuberculosis. ( 28030916 )
2016
42
Clinical and Laboratory Diagnosis of Intestinal Tuberculosis. ( 27231171 )
2016
43
The use of Masson's trichrome staining, second harmonic imaging and two-photon excited fluorescence of collagen in distinguishing intestinal tuberculosis from Crohn's disease. ( 27232282 )
2016
44
Intestinal tuberculosis versus crohn's disease: Clinical and radiological recommendations. ( 27413261 )
2016
45
Primary Enterolith in a Patient with Intestinal Tuberculosis: A Case Report. ( 27853338 )
2016
46
Predictive Factors for Differentiating Between Crohn's Disease and Intestinal Tuberculosis in Koreans. ( 27296940 )
2016
47
An Analysis of the Clinical, Endoscopic, and Pathologic Features of Intestinal Tuberculosis. ( 26974755 )
2016
48
Intestinal tuberculosis masquerading as difficult to treat Crohn disease: a case report. ( 27557645 )
2016
49
Exploration of Serum Proteomic Profiling and Diagnostic Model That Differentiate Crohn's Disease and Intestinal Tuberculosis. ( 27997555 )
2016
50
Misdiagnosis and Mistherapy of Crohn's Disease as Intestinal Tuberculosis: Case Report and Literature Review. ( 26735549 )
2016

Variations for Intestinal Tuberculosis

Expression for Intestinal Tuberculosis

Search GEO for disease gene expression data for Intestinal Tuberculosis.

Pathways for Intestinal Tuberculosis

GO Terms for Intestinal Tuberculosis

Cellular components related to Intestinal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 anchored component of membrane GO:0031225 8.62 GP2 NT5E

Molecular functions related to Intestinal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transporter activity GO:0005215 8.96 ABCA3 ABCB8
2 ATPase activity, coupled to transmembrane movement of substances GO:0042626 8.62 ABCA3 ABCB8

Sources for Intestinal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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